prev  page PLNT3140 Introductory Cytogenetics
Lecture 16, part 2 of 3
next page

E. Genetic maps

Undisplayed Graphic
From left to right, the number of transcripts in chromosomal region, the genetic distance encompassed in that intervel (cM), mapped markers, and a cytologic idiograph are shown.

Genetic distances, measured by recombination, are not always linearly-related to actual physical distance. For example, a comparison of physical and genetic distances on human chromosome 16 shows that the physical distance corresponding to 1 cM (map unit) varies along the length of chromosome 16.
D165S309 -D16S83 - practically next to each other on the chromosome, but very high frequency of recombination between them.
SPN - D16S300 : ~25Mb between them, and almost no recombination.


Undisplayed Graphic

Unless otherwise cited or referenced, all content on this page is licensed under the Creative Commons License Attribution Share-Alike 2.5 Canada

prev  page PLNT3140 Introductory Cytogenetics
Lecture 16, part 2 of 3
next page