Lecture 1

 

Section 1 : Biology : An Introduction

 

            Modules

            1a) Observing life

            1b) Biology as Science

            1c) Themes and concepts

 

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Complementary Material in Campbell (ed. 7)

 

Chap 1.

 Concept 1.1

            -A hierarchy of Biological Organization

 Concept 1.2

            -Emergent Properties of Systems

            -The Power and Limitations of Reductionism

            -Systems Biology

 Concept 1.3 (all)

 Concept 1.5

            -Discovery Science

            -Hypothesis Based Science

            -Limitations in Science

            -Theories in Science

 Concept 1.6 (all)

 

Relevant pages in the text : 2-6, 9-15, 19-21, 24-27

 

Relevant figures and tables : Figs 1.2, 1.3, 1.8, 1.10, 1.15, 1.16, 1.25                                                                                    Tables 1.1

 

 

 

 

 

Lecture 2

 

Section 2 : The Chemistry of Life

 

Modules

2a) Atoms of life

2b) From Atoms to Molecules

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 2

 Concept 2.1

-elements and compounds

-essential elements of life

 Concept 2.2

-subatomic particles

-Atomic number and atomic mass

-Electron configuration and chemical properties

-electron orbitals

 Concept 2.3

-covalent bonds

-molecular shape and function

 Concept 2.4 (all)

 

Relevant pages in the text : 32-34,37-40,43,44

 

Relevant figures and tables : Figs 2.2, 2.4, 2.8, 2.9, 2.10, 2.11, 2.12, 2.15, 2.16, 4.4

                                                Tables 2.1

 

 

 

Lecture 3

 

Section 2 : The Chemistry of Life

 

Modules

2c) Molecules Interacting with Molecules

2d) Water

 

Section 3 : Organic chemistry

 

Modules

3a) Building a Carbon Skeleton

 

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Complementary Material in Campbell (ed. 7)

 

 

Chap. 2

 Concept 2.3

-ionic bond

-Weak chemical bonds

 

 

Chap. 3

 Concept 3.1 (all)

 Concept 3.2

-Cohesion

-solvent of life

 Concept 3.3

-Effect of change in pH

 

Chap. 4

 Concept 4.1 (all)

 Concept 4.2

-Formation of bonds with carbon

 

Relevant Pages in the text : 41, 42, 47, 48, 51-54, 58-61

 

Relevant figures : 2.2, 2.13, 2.15, .3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 4.3, 4.5

 

 

 

Lecture 4

 

Section 3 : Organic chemistry

Modules

3b) Functional groups

3c) Structural Variation

 

Section 4 : Biochemistry of Life

            Modules

4a) From monomers to polymers

 

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Complementary Material in Campbell (ed. 7)

 

Chap.4

 Concept 4.2

-molecular diversity arising from carbon skeleton variation

 Concept 4.3 (all)

 

Chap. 5

 Concept 5.1

-Most macromolecules are polymers, built from monomers

 

Relevant pages in the text : 62-66, 68, 69

 

Relevant figures and tables : Figs. 4.7, 4.8, 5.2

                                                Table 4.10

Lecture 5

 

Section 4 : Biochemistry of Life

            Modules

            4b) Carbohydrates

            4c) Lipids (start)

 

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Complementary Material in Campbell (ed. 7)

 

Chap 5.

 Concept 5.2 (all)

 Concept 5.3

-Fats

 

Relevant pages in the text : 69-76

 

Relevant figures : 5.3, 5.4, 5.5, 5.6, 5.7, 5.8, 5.11, 5.12

 

 

Lecture 6

 

Section 4 : Biochemistry of Life

Modules

4c) Lipids (end)

4d) Proteins

 

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Complementary Material in Campbell (ed. 7)

 

Chap.5

 Concepts 5.3

-phospholipids

-steroids

 Concept 5.4

-polypeptides

-protein conformation and function

 

Relevant pages in the text : 76-83

 

Relevant figures and tables : Figs 5.13, 5.14, 5.15, 5.16, 5.17, 5.18, 5.19, 5.20

                                                Table 5.1

 

 

 

 

Lecture 7

 

Section 4: Biochemistry of life

            Module

            4e) Nucleotides and nucleic acids

 

Section 5: from Biochemistry to Biology

            Module

            5a) The origin of life

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 5

 Concept 5.4

-protein conformation and function

 Concept 5.5

            -Role of nucleic acids

            -Structure of nucleic acids

            -the DNA double helix

 

Chap 8

 Concept 8.3

-The structure and hydrolysis of ATP

 

Chap. 26

 Concept 26.1 (all)

 Concept 26.3

-The first prokaryotes

 

Relevant pages in the text : 84, 86-89, 148, 163, 512-516, 521, 522

 

Relevant figures : 5.21, 5.25, 5.26, 5.27, 8.8, 9.4, 26.2, 26.4, 26.5, 26.10, 26.11

 

 

 

 

Lecture 8

 

Section 6 : A Tour of the Cell

            Modules

            6a) The Prokaryotic cell

            6b) The Eukaryotic cell (Introduction)

            6c) The Nucleus

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 27

 Concept 27.1

-Cell surface structures

-Motility

-Internal and genomic organization

 

Chap. 6

 Concept 6.2 (all)

 Concept 6.3 (all)

 

Relevant pages in the text : 95, 98-103, 534, 536, 537

 

Relevant figures : 6.1, 6.6, 6.7, 6.9a, 6.9b, 6.10, 6.11, 27.2, 27.5, 27.6, 27.7, 27.8

 

 

Lecture 9

 

Section 6 : A Tour of the Cell

            Module

            6d) The Endomembrane System

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 6

 Concept 6.4 (all)

 

Chap. 7

 Concept 7.1

-Synthesis and sidedness of the membrane

 

Relevant pages in the text : 104-108, 129

 

Relevant figures : 6.10, 6.11, 6.12, 6.13, 6.14, 6.15, 6.16, 7.10

 

 

Lecture 10

 

Section 6: A tour of the Cell

            Module

            6e) Cellular Organelles

            6f) the Cytoskeleton

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 6

 Concept 6.5 (all)

 Concept 6.6 (all)

 Concept 6.7

-the Cell wall of plants

 

Chap 26

 Concept 26.4

-Endosymbiotic origin of mitochondria and chloroplasts

 

Relevant pages in the text : 109-118, 523, 524

 

Relevant figures and tables :

Figs 6.16, 6.18, 6.20, 6.21, 6.22, 6.23, 6.24, 6.25, 6.26, 6.27, 26.13

                                    Table 6.1

 

 

Lecture 11

 

Section 6: a Tour of the Cell

            Module

6g) The exterior of the cell

 

Section 7: Plasma Membrane Structure and Function

            Module

            7a) Membrane Structure

 

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Complementary Material in Campbell (ed. 7)

 

Chap 6

 Concept 6.7

            -Extracellular matrix of Animal Cells

 

Chap. 7

 Concept 7.1

-membrane Models : Scientific Enquiry

-Membrane Fluidity

-membrane proteins and their function

 Concept 7.2

            -Permeability of the lipid bilayer

 Concept 7.3

            -Effect of osmosis on water balance

 

Relevant pages in the text : 119-121, 124-127, 130-132

 

Relevant figures : 6.28, 6.29, 6.30, 6.31, 7.1, 7.2, 7.3, 7.5, 7.6, 7.7, 7.8, 7.11, 7.12

 

 

 

Lecture 12

 

Section 7 Plasma Membrane Structure and Function

            Module

            7b) Passive Diffusion and Osmosis

            7c) Membrane Function : Transport

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 7

 Concept 7.1

            -Membrane Protein and their Function

 Concept 7.2

            -Transport Protein

 Concept 7.3 (all)

 Concept 7.4 (all)

 Concept 7.5 (all)

 

Relevant pages in the text : 127, 128, 130-138

 

Relevant figures : 7.9, 7.12, 7.13, 7.15, 7.17, 7.18, 7.19, 7.20

 

 

Lecture 13

 

Section 7 : Plasma Membrane Structure and Function

            Module

            7d) Membrane Function: sensing the environment

 

Section 8 : Foundations of Metabolism

            Module

            8a) Energy and Thermodynamics

           

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Complementary Material in Campbell (ed. 7)

 

Chap. 11

 Concept 11.1 (all)

 

Chap. 8

 Concept 8.1 (all)

 

Relevant pages in the text : 141-144, 201-205

Relevant figures : 8.2, 8.3, 8.4, 11.3, 11.4, 11.5

 

 

Lecture 14

 

Section 8 : Foundation of Metabolism

            Module

            8b) Energy and chemical reactions

            8c) Free energy and Metabolism

            8d) Energy of Activation and Enzymes

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 8

 Concept 8.2 (all)

 Concept 8.3 (all)

 Concept 8.4

            -Activation energy barrier

            -How enzymes lower Ea barrier

            -Substrate specificity of Enzymes

            -Catalysis in an enzymeÕs active site

 

Relevant pages in the text : 145-153

 

Relevant figures : 8.5, 8.6, 8.7, 8.8, 8.9, 8.10, 8.11, 8.12, 8.14, 8.15, 8.16, 8.17

 

 

Lecture 15

 

Section 9: Energy Conservation

            Module

            9a) General Strategy

            9b) Harvesting Chemical Energy

                        9bi) Glycolysis overview

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 9

 Concept 9.1 (all)

 Concept 9.2 (all)

 

Relevant pages in the text : 160-165

 

Relevant figures : 9.2, 9.3, 9.4, 9.5, 9.6, 9.7, 9.8, 9.14

 

 

Lecture 16

 

Section 9: Energy Conservation

            Module

            9b) Harvesting Chemical Energy

                        9bii) Glycolysis

                        9biii) Citric Acid Cycle

                        9biv) Electron transport and chemiosmotic ATP synthesis

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 9

 Concept 9.2 (all)

 Concept 9.3 (all)

 Concept 9.4 (all)

 

Relevant pages in the text : 164-174

 

Relevant figures : 9.8, 9.9, 9.10, 9.11, 9.12, 9.13, 9.14, 9.15, 9.16

 

 

Lecture 17

 

Section 9: Energy Conservation

            Module

            9b) Harvesting Chemical Energy

                        9bv) Fermentation

            9c) Harvesting Light Energy

 

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Complementary Material in Campbell (ed. 7)

 

Chap. 9

 Concept 9.5

            -Types of fermentation

            -fermentation and respiration compared

 

Chap. 10

 Concept 10.1

            -Chloroplasts : the sites of photosynthesis in plants

            -The 2 stages of photosynthesis ; a preview

 

 

 Concept 10.2

            -Excitaton of chlorophyll by light

            -non-cyclic electron flow

            -cyclic electron flow

            -comparison of chemiosmosis in chloroplasts and mitochondria

Concept 10.3 (all)

 

Relevant pages in the text : 174-176, 181-185, 188, 190-193

 

Relevant figures : 9.17, 9.18, 10.3, 10.4, 10.5,10.7, 10.9, 10.14, 10.16, 10.17, 10.18, 10.21