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Hélène 2015Hélène Perreault, Ph.D.

Professor

Chemistry Department

University of Manitoba

 

Room 550 Parker Building

Tel (204) 474-7418             

Fax (204) 474-7608
E-mail                          

 

 

 

 

 

                                               

 

RESEARCH INTERESTS

Bioanalytical Chemistry

Proteins play very important roles in all types of organisms. They can act as enzymes, catalysts, oxygen carriers, structure building blocks, among many other possible roles. Normal protein function results of a combination of amino acid sequence, 3-D structure and sometimes aggregation with other proteins or biomolecules. If sequence (thus often structure) is altered, protein function changes, possibly causing diseases or other problems.

Over the past twenty years, we have been interested in characterizing glycoproteins from several sources, using mass spectrometry as our main analytical tool. Because proteins in cells always occur in very complex mixtures, preliminary steps such as electrophoresis and chromatography are often required in sample preparation. The mass spectrometer in our laboratory is equipped with matrix-assisted laser desorption/ionization (MALDI), and we also have HPLC systems for sample preparation.

See a list of recent publications.

We have projects on the characterization of antibodies and other glycoproteins, we work in collaboration with medical researchers, microbiologists, biochemists and government researchers. We also analyze samples as a service to our Department and to the scientific community.

For pictures of our group click here.

 

 

TEACHING in 2017 (winter):

 

Bioanalytical Chemistry, CHEM 4590.

This is a half-year, 3 credit-hour fall course. Visit the course web site for schedule and content.

ACT, CHEM 4610 (Advanced Mass Spectrometry)

 

 

Chemistry Department page