Hélène 2015Hélène Perreault, Ph.D.


Chemistry Department

University of Manitoba


Room 550 Parker Building

Tel (204) 474-7418             

Fax (204) 474-7608









Bioanalytical Chemistry

Proteins play very important roles in all types of organisms. They can act as enzymes, catalysts, oxygen carriers, structure building blocks, among many other possible roles. Normal protein function results of a combination of amino acid sequence, 3-D structure and sometimes aggregation with other proteins or biomolecules. If sequence (thus often structure) is altered, protein function changes, possibly causing diseases or other problems.

Over the past twenty years, we have been interested in characterizing glycoproteins from several sources, using mass spectrometry as our main analytical tool. Because proteins in cells always occur in very complex mixtures, preliminary steps such as electrophoresis and chromatography are often required in sample preparation. The mass spectrometer in our laboratory is equipped with matrix-assisted laser desorption/ionization (MALDI), and we also have HPLC systems for sample preparation.


We have projects on the characterization of antibodies and other glycoproteins, we work in collaboration with medical researchers, microbiologists, biochemists and government researchers. We also analyze samples as a service to our Department and to the scientific community.



TEACHING in 2018-2019 (winter):

ACT, CHEM 4610 (Advanced Mass Spectrometry)

Instrumental Analysis, CHEM 3590

Bioanalytical Chemistry, CHEM 4590




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