H AZAE970102 D The substitution matrix derived from spatially conserved motifs (Azarya-Sprinzak et al., 1997) R PMID:9488136 A Azarya-Sprinzak, E., Naor, D., Wolfson, H.J. and Nussinov, R. T Interchanges of spatially neighbouring residues in structurally conserved environments. J Protein Engineering 10, 1109-1122 (1997) M rows = ARNDCQEGHILKMFPSTWYV, cols = ARNDCQEGHILKMFPSTWYV 8 1 11 0 7 11 0 9 12 16 2 -7 -5 -8 14 1 12 10 13 -9 17 1 10 8 10 -6 13 8 1 0 7 8 0 0 0 18 -2 2 2 4 -1 2 1 5 5 -3 -10 -11 -12 4 -12 -10 -8 -3 11 0 -7 -9 -10 2 -9 -7 -8 -4 8 10 1 14 10 11 -10 16 13 0 2 -12 -9 20 1 -2 -4 -6 1 -3 0 -5 -2 3 6 -5 4 -2 -8 -9 -9 3 -10 -7 -3 -1 7 6 -10 3 8 -1 1 8 7 -2 0 0 10 3 -9 -9 1 -9 -5 33 0 4 6 6 -2 4 3 6 2 -7 -6 4 -5 -5 5 7 -2 2 2 3 -3 2 1 1 3 -2 -4 2 -3 -3 3 4 6 -1 -4 -4 -4 0 -5 -5 -1 -1 4 3 -7 2 4 -4 -3 -1 6 -1 -3 -4 -5 0 -4 -1 -1 0 3 2 -4 2 3 -4 -1 0 2 3 -4 -10 -11 -12 5 -12 -11 -7 -3 11 6 -13 1 7 -5 -5 -1 4 2 12 //