H WEIL970101 D WAC matrix constructed from amino acid comparative profiles (Wei et al., 1997) R PMID:9390315 A Wei, L., Altman, R.B. and Chang, J.T. T Using the radial distributions of physical features to compare amino acid environments and align amino acid sequences. J Pac. Symp. Biocomput. 1997 5, 465-476 (1997) M rows = ARNDCQEGHILKMFPSTWYV, cols = ARNDCQEGHILKMFPSTWYV 4 -1 4 0 0 4 -2 -1 0 4 0 -1 0 -2 4 0 0 1 -1 0 4 -3 -1 0 0 -2 0 4 -1 -1 0 -2 0 0 -2 4 0 0 0 -1 0 0 -1 -1 4 0 -2 -1 -4 0 0 -4 -2 -1 4 0 -1 -1 -3 0 0 -3 -1 -1 1 4 -1 2 0 -1 -2 0 -1 -1 0 -2 -2 4 1 0 0 -1 1 1 -1 0 0 2 2 0 4 0 -2 -1 -4 0 0 -4 -2 0 0 1 -2 2 4 0 0 0 -1 -1 0 -1 0 0 0 0 0 1 0 4 0 -1 1 -1 0 0 -2 0 -1 -1 -1 0 0 -2 0 4 0 0 1 -1 0 1 -1 0 -1 0 0 0 0 -2 0 1 4 0 0 -1 -3 0 0 -2 -2 0 0 1 -2 2 2 0 -1 -1 4 0 -1 0 -3 0 1 -4 -2 0 0 0 -2 0 1 -1 -1 -1 1 4 1 -2 -1 -3 0 -1 -4 -2 -1 2 1 -3 1 0 0 -1 0 0 0 4 //