#include "phylip.h" #include "disc.h" #include "dollo.h" /* version 3.6. (c) Copyright 1993-2004 by the University of Washington. Written by Joseph Felsenstein, Akiko Fuseki, Sean Lamont, and Andrew Keeffe. Permission is granted to copy and use this program provided no fee is charged for it and provided that this copyright notice is not removed. */ #define maxtrees 100 /* maximum number of tied trees stored */ #ifndef OLDC /* function prototypes */ void getoptions(void); void allocrest(void); void doinit(void); void inputoptions(void); void doinput(void); void dollop_count(node *, steptr, steptr); void preorder(node *, steptr, steptr, long, boolean, long, bitptr, pointptr); void evaluate(node *); void savetree(void); void dollop_addtree(long *); void tryadd(node *, node **, node **); void addpreorder(node *, node *, node *); void tryrearr(node *, node **, boolean *); void repreorder(node *, node **, boolean *); void rearrange(node **); void describe(void); void initdollopnode(node **, node **, node *, long, long, long *, long *, initops, pointarray, pointarray, Char *, Char *, FILE *); void maketree(void); void reallocchars(void); /* function prototypes */ #endif Char infilename[FNMLNGTH], outfilename[FNMLNGTH], intreename[FNMLNGTH], outtreename[FNMLNGTH], weightfilename[FNMLNGTH], ancfilename[FNMLNGTH]; node *root; long col, msets, ith, j, l, njumble, jumb; long inseed, inseed0; boolean jumble, usertree, weights, thresh, ancvar, questions, dollo, trout, progress, treeprint, stepbox, ancseq, mulsets, firstset, justwts; boolean *ancone, *anczero, *ancone0, *anczero0; pointptr treenode; /* pointers to all nodes in tree */ double threshold; double *threshwt; longer seed; long *enterorder; double **fsteps; steptr numsteps; bestelm *bestrees; Char *guess; gbit *garbage; char *progname; /* Variables for treeread */ boolean goteof, firsttree, haslengths, phirst; pointarray nodep; node *grbg; long *zeros; /* Local variables for maketree, propagated globally for C version: */ long minwhich; double like, bestyet, bestlike, bstlike2, minsteps; boolean lastrearr; double nsteps[maxuser]; node *there; long fullset; long shimotrees; bitptr zeroanc, oneanc; long *place; Char ch; boolean *names; steptr numsone, numszero; bitptr steps; void getoptions() { /* interactively set options */ long loopcount, loopcount2; Char ch, ch2; fprintf(outfile,"\nDollo and polymorphism parsimony algorithm,"); fprintf(outfile," version %s\n\n",VERSION); putchar('\n'); ancvar = false; dollo = true; jumble = false; njumble = 1; thresh = false; threshold = spp; trout = true; usertree = false; goteof = false; weights = false; justwts = false; printdata = false; progress = true; treeprint = true; stepbox = false; ancseq = false; loopcount = 0; for (;;) { cleerhome(); printf("\nDollo and polymorphism parsimony algorithm, version %s\n\n", VERSION); printf("Settings for this run:\n"); printf(" U Search for best tree? %s\n", (usertree ? "No, use user trees in input file" : "Yes")); printf(" P Parsimony method? %s\n", dollo ? "Dollo" : "Polymorphism"); if (!usertree) { printf(" J Randomize input order of species?"); if (jumble) printf(" Yes (seed =%8ld,%3ld times)\n", inseed0, njumble); else printf(" No. Use input order\n"); } printf(" T Use Threshold parsimony?"); if (thresh) printf(" Yes, count steps up to%4.1f per char.\n", threshold); else printf(" No, use ordinary parsimony\n"); printf(" A Use ancestral states in input file? %s\n", ancvar ? "Yes" : "No"); printf(" W Sites weighted? %s\n", (weights ? "Yes" : "No")); printf(" M Analyze multiple data sets?"); if (mulsets) printf(" Yes, %2ld %s\n", msets, (justwts ? "sets of weights" : "data sets")); else printf(" No\n"); printf(" 0 Terminal type (IBM PC, ANSI, none)? %s\n", ibmpc ? "IBM PC" : ansi ? "ANSI" : "(none)"); printf(" 1 Print out the data at start of run %s\n", printdata ? "Yes" : "No"); printf(" 2 Print indications of progress of run %s\n", progress ? "Yes" : "No"); printf(" 3 Print out tree %s\n", treeprint ? "Yes" : "No"); printf(" 4 Print out steps in each character %s\n", stepbox ? "Yes" : "No"); printf(" 5 Print states at all nodes of tree %s\n", ancseq ? "Yes" : "No"); printf(" 6 Write out trees onto tree file? %s\n", trout ? "Yes" : "No"); if(weights && justwts){ printf( "WARNING: W option and Multiple Weights options are both on. "); printf( "The W menu option is unnecessary and has no additional effect. \n"); } printf("\nAre these settings correct? "); printf("(type Y or the letter for one to change)\n"); #ifdef WIN32 phyFillScreenColor(); #endif fflush(stdout); scanf("%c%*[^\n]", &ch); getchar(); uppercase(&ch); if (ch == 'Y') break; if (((!usertree) && (strchr("WAPJTUM1234560", ch) != NULL)) || (usertree && ((strchr("WAPTUM1234560", ch) != NULL)))){ switch (ch) { case 'A': ancvar = !ancvar; break; case 'P': dollo = !dollo; break; case 'J': jumble = !jumble; if (jumble) initjumble(&inseed, &inseed0, seed, &njumble); else njumble = 1; break; case 'W': weights = !weights; break; case 'T': thresh = !thresh; if (thresh) initthreshold(&threshold); break; case 'U': usertree = !usertree; break; case 'M': mulsets = !mulsets; if (mulsets){ printf("Multiple data sets or multiple weights?"); loopcount2 = 0; do { printf(" (type D or W)\n"); #ifdef WIN32 phyFillScreenColor(); #endif fflush(stdout); scanf("%c%*[^\n]", &ch2); getchar(); if (ch2 == '\n') ch2 = ' '; uppercase(&ch2); countup(&loopcount2, 10); } while ((ch2 != 'W') && (ch2 != 'D')); justwts = (ch2 == 'W'); if (justwts) justweights(&msets); else initdatasets(&msets); if (!jumble) { jumble = true; initjumble(&inseed, &inseed0, seed, &njumble); } } break; case '0': initterminal(&ibmpc, &ansi); break; case '1': printdata = !printdata; break; case '2': progress = !progress; break; case '3': treeprint = !treeprint; break; case '4': stepbox = !stepbox; break; case '5': ancseq = !ancseq; break; case '6': trout = !trout; break; } } else printf("Not a possible option!\n"); countup(&loopcount, 100); } } /* getoptions */ void reallocchars() { long i; free(extras); free(weight); free(threshwt); free(numsteps); free(ancone); free(anczero); free(ancone0); free(anczero0); free(numsone); free(numszero); free(guess); if (usertree) { for (i = 1; i <= maxuser; i++){ free(fsteps); fsteps[i - 1] = (double *)Malloc(chars*sizeof(double)); } } extras = (steptr)Malloc(chars*sizeof(long)); weight = (steptr)Malloc(chars*sizeof(long)); threshwt = (double *)Malloc(chars*sizeof(double)); numsteps = (steptr)Malloc(chars*sizeof(long)); ancone = (boolean *)Malloc(chars*sizeof(boolean)); anczero = (boolean *)Malloc(chars*sizeof(boolean)); ancone0 = (boolean *)Malloc(chars*sizeof(boolean)); anczero0 = (boolean *)Malloc(chars*sizeof(boolean)); numsone = (steptr)Malloc(chars*sizeof(long)); numszero = (steptr)Malloc(chars*sizeof(long)); guess = (Char *)Malloc(chars*sizeof(Char)); } void allocrest() { long i; extras = (steptr)Malloc(chars*sizeof(long)); weight = (steptr)Malloc(chars*sizeof(long)); threshwt = (double *)Malloc(chars*sizeof(double)); if (usertree) { fsteps = (double **)Malloc(maxuser*sizeof(double *)); for (i = 1; i <= maxuser; i++) fsteps[i - 1] = (double *)Malloc(chars*sizeof(double)); } bestrees = (bestelm *) Malloc(maxtrees*sizeof(bestelm)); for (i = 1; i <= maxtrees; i++) bestrees[i - 1].btree = (long *)Malloc(nonodes*sizeof(long)); numsteps = (steptr)Malloc(chars*sizeof(long)); nayme = (naym *)Malloc(spp*sizeof(naym)); enterorder = (long *)Malloc(spp*sizeof(long)); place = (long *)Malloc(nonodes*sizeof(long)); ancone = (boolean *)Malloc(chars*sizeof(boolean)); anczero = (boolean *)Malloc(chars*sizeof(boolean)); ancone0 = (boolean *)Malloc(chars*sizeof(boolean)); anczero0 = (boolean *)Malloc(chars*sizeof(boolean)); numsone = (steptr)Malloc(chars*sizeof(long)); numszero = (steptr)Malloc(chars*sizeof(long)); guess = (Char *)Malloc(chars*sizeof(Char)); zeroanc = (bitptr)Malloc(words*sizeof(long)); oneanc = (bitptr)Malloc(words*sizeof(long)); steps = (bitptr)Malloc(words*sizeof(long)); } /* allocrest */ void doinit() { /* initializes variables */ inputnumbers(&spp, &chars, &nonodes, 1); words = chars / bits + 1; getoptions(); alloctree(&treenode); setuptree(treenode); allocrest(); } /* doinit */ void inputoptions() { /* input the information on the options */ long i; if(justwts){ if(firstset){ scan_eoln(infile); if (ancvar) { inputancestors(anczero0, ancone0); } } for (i = 0; i < (chars); i++) weight[i] = 1; inputweights(chars, weight, &weights); } else { if (!firstset) { samenumsp(&chars, ith); reallocchars(); } scan_eoln(infile); for (i = 0; i < (chars); i++) weight[i] = 1; if (ancvar) inputancestors(anczero0, ancone0); if (weights) inputweights(chars, weight, &weights); } if ((weights || justwts) && printdata) printweights(outfile, 0, chars, weight, "Characters"); for (i = 0; i < (chars); i++) { if (!ancvar) { anczero[i] = true; ancone[i] = false; } else { anczero[i] = anczero0[i]; ancone[i] = ancone0[i]; } } if (ancvar && printdata) printancestors(outfile, anczero, ancone); questions = false; for (i = 0; i < (chars); i++) { questions = (questions || (ancone[i] && anczero[i])); threshwt[i] = threshold * weight[i]; } } /* inputoptions */ void doinput() { /* reads the input data */ inputoptions(); if(!justwts || firstset) inputdata(treenode, dollo, printdata, outfile); } /* doinput */ void dollop_count(node *p, steptr numsone, steptr numszero) { /* counts the number of steps in a fork of the tree. The program spends much of its time in this PROCEDURE */ long i, j, l; if (dollo) { for (i = 0; i < (words); i++) steps[i] = (treenode[p->back->index - 1]->stateone[i] & p->statezero[i] & zeroanc[i]) | (treenode[p->back->index - 1]->statezero[i] & p->stateone[i] & fullset & (~zeroanc[i])); } else { for (i = 0; i < (words); i++) steps[i] = treenode[p->back->index - 1]->stateone[i] & treenode[p->back->index - 1]->statezero[i] & p->stateone[i] & p->statezero[i]; } j = 1; l = 0; for (i = 0; i < (chars); i++) { l++; if (l > bits) { l = 1; j++; } if (((1L << l) & steps[j - 1]) != 0) { assert(j <= words); /* checking array indexing */ if (((1L << l) & zeroanc[j - 1]) != 0) numszero[i] += weight[i]; else numsone[i] += weight[i]; } } } /* dollop_count */ void preorder(node *p, steptr numsone, steptr numszero, long words, boolean dollo, long fullset, bitptr zeroanc, pointptr treenode) { /* go back up tree setting up and counting interior node states */ if (!p->tip) { correct(p, fullset, dollo, zeroanc, treenode); preorder(p->next->back, numsone,numszero, words, dollo, fullset, zeroanc, treenode); preorder(p->next->next->back, numsone,numszero, words, dollo, fullset, zeroanc, treenode); } if (p->back != NULL) dollop_count(p, numsone,numszero); } /* preorder */ void evaluate(node *r) { /* Determines the number of losses or polymorphisms needed for a tree. This is the minimum number needed to evolve chars on this tree */ long i, stepnum, smaller; double sum, term; sum = 0.0; for (i = 0; i < (chars); i++) { numszero[i] = 0; numsone[i] = 0; } for (i = 0; i < (words); i++) zeroanc[i] = fullset; postorder(r); preorder(r, numsone, numszero, words, dollo, fullset, zeroanc, treenode); for (i = 0; i < (words); i++) zeroanc[i] = 0; postorder(r); preorder(r, numsone, numszero, words, dollo, fullset, zeroanc, treenode); for (i = 0; i < (chars); i++) { smaller = spp * weight[i]; numsteps[i] = smaller; if (anczero[i]) { numsteps[i] = numszero[i]; smaller = numszero[i]; } if (ancone[i] && numsone[i] < smaller) numsteps[i] = numsone[i]; stepnum = numsteps[i] + extras[i]; if (stepnum <= threshwt[i]) term = stepnum; else term = threshwt[i]; sum += term; if (usertree && which <= maxuser) fsteps[which - 1][i] = term; guess[i] = '?'; if (!ancone[i] || (anczero[i] && numszero[i] < numsone[i])) guess[i] = '0'; else if (!anczero[i] || (ancone[i] && numsone[i] < numszero[i])) guess[i] = '1'; } if (usertree && which <= maxuser) { nsteps[which - 1] = sum; if (which == 1) { minwhich = 1; minsteps = sum; } else if (sum < minsteps) { minwhich = which; minsteps = sum; } } like = -sum; } /* evaluate */ void savetree() { /* record in place where each species has to be added to reconstruct this tree */ long i, j; node *p; boolean done; for (i = 0; i < (nonodes); i++) place[i] = 0; place[root->index - 1] = 1; for (i = 1; i <= (spp); i++) { p = treenode[i - 1]; while (place[p->index - 1] == 0) { place[p->index - 1] = i; p = p->back; if (p != NULL) p = treenode[p->index - 1]; } if (i > 1) { place[i - 1] = place[p->index - 1]; j = place[p->index - 1]; done = false; while (!done) { place[p->index - 1] = spp + i - 1; p = treenode[p->index - 1]; p = p->back; done = (p == NULL); if (!done) done = (place[p->index - 1] != j); } } } } /* savetree */ void dollop_addtree(long *pos) { /*puts tree from ARRAY place in its proper position in ARRAY bestrees */ long i; for (i =nextree - 1; i >= (*pos); i--) { memcpy(bestrees[i].btree, bestrees[i - 1].btree, spp*sizeof(long)); bestrees[i].gloreange = bestrees[i - 1].gloreange; bestrees[i].locreange = bestrees[i - 1].locreange; bestrees[i].collapse = bestrees[i - 1].collapse; } for (i = 0; i < (spp); i++) bestrees[(*pos) - 1].btree[i] = place[i]; nextree++; } /* dollop_addtree */ void tryadd(node *p, node **item, node **nufork) { /* temporarily adds one fork and one tip to the tree. if the location where they are added yields greater "likelihood" than other locations tested up to that time, then keeps that location as there */ long pos; boolean found; add(p, *item, *nufork, &root, treenode); evaluate(root); if (lastrearr) { if (like >= bstlike2) { savetree(); if (like > bstlike2) { bestlike = bstlike2 = like; pos = 1; nextree = 1; dollop_addtree(&pos); } else { pos = 0; findtree(&found, &pos, nextree, place, bestrees); /* findtree calls for a bestelm* but is getting */ /* a long**, LM */ if (!found) { if (nextree <= maxtrees) dollop_addtree(&pos); } } } } if (like > bestyet) { bestyet = like; there = p; } re_move(item, nufork, &root, treenode); } /* tryadd */ void addpreorder(node *p, node *item_, node *nufork_) { /* traverses a binary tree, calling PROCEDURE tryadd at a node before calling tryadd at its descendants */ node *item= item_; node *nufork = nufork_; if (p == NULL) return; tryadd(p, &item,&nufork); if (!p->tip) { addpreorder(p->next->back, item, nufork); addpreorder(p->next->next->back, item, nufork); } } /* addpreorder */ void tryrearr(node *p, node **r, boolean *success) { /* evaluates one rearrangement of the tree. if the new tree has greater "likelihood" than the old one sets success := TRUE and keeps the new tree. otherwise, restores the old tree */ node *frombelow, *whereto, *forknode; double oldlike; if (p->back == NULL) return; forknode = treenode[p->back->index - 1]; if (forknode->back == NULL) return; oldlike = bestyet; if (p->back->next->next == forknode) frombelow = forknode->next->next->back; else frombelow = forknode->next->back; whereto = forknode->back; re_move(&p, &forknode, &root, treenode); add(whereto, p, forknode, &root, treenode); evaluate(*r); if (oldlike - like < LIKE_EPSILON) { re_move(&p, &forknode, &root, treenode); add(frombelow, p, forknode, &root, treenode); } else { (*success) = true; bestyet = like; } } /* tryrearr */ void repreorder(node *p, node **r, boolean *success) { /* traverses a binary tree, calling PROCEDURE tryrearr at a node before calling tryrearr at its descendants */ if (p == NULL) return; tryrearr(p, r,success); if (!p->tip) { repreorder(p->next->back, r,success); repreorder(p->next->next->back, r,success); } } /* repreorder */ void rearrange(node **r_) { /* traverses the tree (preorder), finding any local rearrangement which decreases the number of steps. if traversal succeeds in increasing the tree's "likelihood", PROCEDURE rearrange runs traversal again */ node **r = r_; boolean success = true; while (success) { success = false; repreorder(*r, r,&success); } } /* rearrange */ void describe() { /* prints ancestors, steps and table of numbers of steps in each character */ if (treeprint) fprintf(outfile, "\nrequires a total of %10.3f\n", -like); if (stepbox) { putc('\n', outfile); writesteps(weights, dollo, numsteps); } if (questions) guesstates(guess); if (ancseq) { hypstates(fullset, dollo, guess, treenode, root, garbage, zeroanc, oneanc); putc('\n', outfile); } putc('\n', outfile); if (trout) { col = 0; treeout(root, nextree, &col, root); } } /* describe */ void initdollopnode(node **p, node **grbg, node *q, long len, long nodei, long *ntips, long *parens, initops whichinit, pointarray treenode, pointarray nodep, Char *str, Char *ch, FILE *intree) { /* initializes a node */ /* LM 7/27 I added this function and the commented lines around */ /* treeread() to get the program running, but all 4 move programs*/ /* are improperly integrated into the v4.0 support files. As is */ /* this is a patchwork function */ boolean minusread; double valyew, divisor; switch (whichinit) { case bottom: gnutreenode(grbg, p, nodei, chars, zeros); treenode[nodei - 1] = *p; break; case nonbottom: gnutreenode(grbg, p, nodei, chars, zeros); break; case tip: match_names_to_data (str, treenode, p, spp); break; case length: /* if there is a length, read it and discard value */ processlength(&valyew, &divisor, ch, &minusread, intree, parens); break; default: /*cases hslength,hsnolength,treewt,unittrwt,iter,*/ break; } } /* initdollopnode */ void maketree() { /* constructs a binary tree from the pointers in treenode. adds each node at location which yields highest "likelihood" then rearranges the tree for greatest "likelihood" */ long i, j, numtrees, nextnode; double gotlike; node *item, *nufork, *dummy, *p; fullset = (1L << (bits + 1)) - (1L << 1); if (!usertree) { for (i = 1; i <= (spp); i++) enterorder[i - 1] = i; if (jumble) randumize(seed, enterorder); root = treenode[enterorder[0] - 1]; add(treenode[enterorder[0] - 1], treenode[enterorder[1] - 1], treenode[spp], &root, treenode); if (progress) { printf("Adding species:\n"); writename(0, 2, enterorder); #ifdef WIN32 phyFillScreenColor(); #endif } lastrearr = false; for (i = 3; i <= (spp); i++) { bestyet = -350.0 * spp * chars; item = treenode[enterorder[i - 1] - 1]; nufork = treenode[spp + i - 2]; addpreorder(root, item, nufork); add(there, item, nufork, &root, treenode); like = bestyet; rearrange(&root); if (progress) { writename(i - 1, 1, enterorder); #ifdef WIN32 phyFillScreenColor(); #endif } lastrearr = (i == spp); if (lastrearr) { if (progress) { printf("\nDoing global rearrangements\n"); printf(" !"); for (j = 1; j <= (nonodes); j++) if ( j % (( nonodes / 72 ) + 1 ) == 0 ) putchar('-'); printf("!\n"); #ifdef WIN32 phyFillScreenColor(); #endif } bestlike = bestyet; if (jumb == 1) { bstlike2 = bestlike; nextree = 1; } do { if (progress) printf(" "); gotlike = bestlike; for (j = 0; j < (nonodes); j++) { bestyet = - 350.0 * spp * chars; item = treenode[j]; if (item != root) { nufork = treenode[j]->back; re_move(&item, &nufork, &root, treenode); there = root; addpreorder(root, item, nufork); add(there, item, nufork, &root, treenode); } if (progress) { if ( j % (( nonodes / 72 ) + 1 ) == 0 ) putchar('.'); fflush(stdout); } } if (progress) { putchar('\n'); #ifdef WIN32 phyFillScreenColor(); #endif } } while (bestlike > gotlike); } } if (progress) putchar('\n'); for (i = spp - 1; i >= 1; i--) re_move(&treenode[i], &dummy, &root, treenode); if (jumb == njumble) { if (treeprint) { putc('\n', outfile); if (nextree == 2) fprintf(outfile, "One most parsimonious tree found:\n"); else fprintf(outfile, "%6ld trees in all found\n", nextree - 1); } if (nextree > maxtrees + 1) { if (treeprint) fprintf(outfile, "here are the first%4ld of them\n", (long)maxtrees); nextree = maxtrees + 1; } if (treeprint) putc('\n', outfile); for (i = 0; i <= (nextree - 2); i++) { root = treenode[0]; add(treenode[0], treenode[1], treenode[spp], &root, treenode); for (j = 3; j <= spp; j++) { add(treenode[bestrees[i].btree[j - 1] - 1], treenode[j - 1], treenode[spp + j - 2], &root, treenode);} evaluate(root); printree(1.0, treeprint, root); describe(); for (j = 1; j < (spp); j++) re_move(&treenode[j], &dummy, &root, treenode); } } } else { /* Open in binary: ftell() is broken for UNIX line-endings under WIN32 */ openfile(&intree,INTREE,"input tree file", "rb",progname,intreename); numtrees = countsemic(&intree); if (numtrees > 2){ initseed(&inseed, &inseed0, seed); printf("\n"); } if (treeprint) { fprintf(outfile, "User-defined tree"); if (numtrees > 1) putc('s', outfile); fprintf(outfile, ":\n"); } names = (boolean *)Malloc(spp*sizeof(boolean)); which = 1; firsttree = true; /**/ nodep = NULL; /**/ nextnode = 0; /**/ haslengths = 0; /**/ phirst = 0; /**/ zeros = (long *)Malloc(chars*sizeof(long)); /**/ for (i = 0; i < chars; i++) /**/ zeros[i] = 0; /**/ while (which <= numtrees) { treeread(intree, &root, treenode, &goteof, &firsttree, nodep, &nextnode, &haslengths, &grbg, initdollopnode,false,nonodes); for (i = spp; i < (nonodes); i++) { p = treenode[i]; for (j = 1; j <= 3; j++) { p->stateone = (bitptr)Malloc(words*sizeof(long)); p->statezero = (bitptr)Malloc(words*sizeof(long)); p = p->next; } } /* debug: see comment at initdollopnode() */ if (treeprint) fprintf(outfile, "\n\n"); evaluate(root); printree(1.0, treeprint, root); describe(); which++; } FClose(intree); fprintf(outfile, "\n\n"); if (numtrees > 1 && chars > 1) standev(numtrees, minwhich, minsteps, nsteps, fsteps, seed); free(names); } if (jumb == njumble) { if (progress) { printf("Output written to file \"%s\"\n\n", outfilename); if (trout) printf("Trees also written onto file \"%s\"\n\n", outtreename); } if (ancseq) freegarbage(&garbage); } } /* maketree */ int main(int argc, Char *argv[]) { /* Dollo or polymorphism parsimony by uphill search */ #ifdef MAC argc = 1; /* macsetup("Dollop",""); */ argv[0] = "Dollop"; #endif init(argc, argv); /* reads in spp, chars, and the data. Then calls maketree to construct the tree */ progname = argv[0]; openfile(&infile,INFILE,"input file", "r",argv[0],infilename); openfile(&outfile,OUTFILE,"output file", "w",argv[0],outfilename); ibmpc = IBMCRT; ansi = ANSICRT; garbage = NULL; mulsets = false; msets = 1; firstset = true; bits = 8*sizeof(long) - 1; doinit(); if (weights || justwts) openfile(&weightfile,WEIGHTFILE,"weights file","r",argv[0],weightfilename); if (trout) openfile(&outtree,OUTTREE,"output tree file", "w",argv[0],outtreename); if(ancvar) openfile(&ancfile,ANCFILE,"ancestors file", "r",argv[0],ancfilename); if (dollo) fprintf(outfile, "Dollo"); else fprintf(outfile, "Polymorphism"); fprintf(outfile, " parsimony method\n\n"); if (printdata && justwts) fprintf(outfile, "%2ld species, %3ld characters\n\n", spp, chars); for (ith = 1; ith <= (msets); ith++) { if (msets > 1 && !justwts) { fprintf(outfile, "Data set # %ld:\n\n",ith); if (progress) printf("\nData set # %ld:\n",ith); } if (justwts){ fprintf(outfile, "Weights set # %ld:\n\n", ith); if (progress) printf("\nWeights set # %ld:\n\n", ith); } if (printdata && !justwts) fprintf(outfile, "%2ld species, %3ld characters\n\n", spp, chars); doinput(); if (ith == 1) firstset = false; for (jumb = 1; jumb <= njumble; jumb++) maketree(); } /* this would be an appropriate place to deallocate memory, including these items: free(steps); */ FClose(infile); FClose(outfile); FClose(outtree); #ifdef MAC fixmacfile(outfilename); fixmacfile(outtreename); #endif #ifdef WIN32 phyRestoreConsoleAttributes(); #endif return 0; } /* Dollo or polymorphism parsimony by uphill search */