This file is a Amino-acid similarity file for use with BOX. Is resembles the GCG simplify.txt, but similarities contained in this file are not automatically set-forming. This means: The line I LVM means that I is similar to L,V and M and also that L,V,M are similar to I. It does not imply that L is similar to V or to M. For achieving this, more lines (the next ones) are necessary. Although is seems weird, this feature has been chosen DELIBERATELY because I think it could be helpful in some cases. Other format requirements are the same as for SIMPLIFY.TXT in the GCG-package. .. F YW Y WF W YF I LVM L VMI V MVI R KH K HR H RK G A A GS T S S TA D EN E DQ N QD Q NE