BLASTP 2.2.30+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: Non-redundant UniProtKB/SwissProt sequences
462,819 sequences; 173,567,248 total letters
Query= gi|33862495|ref|NP_894055.1| Amino acid permease:Permease for amino
acids and related comp... [Prochlorococcus marinus str. MIT 9313]
Length=615
Score E
Sequences producing significant alignments: (Bits) Value
sp|P96589.1|YDAO_BACSU RecName: Full=Uncharacterized amino acid ... 374 3e-119
sp|P0AA48.1|PLAP_ECO57 RecName: Full=Low-affinity putrescine imp... 54.3 2e-06
sp|P76037.2|PUUP_ECOLI RecName: Full=Putrescine importer PuuP [E... 47.8 2e-04
sp|P63116.1|AAA1_RAT RecName: Full=Asc-type amino acid transport... 41.6 0.016
sp|Q9NS82.1|AAA1_HUMAN RecName: Full=Asc-type amino acid transpo... 41.6 0.020
sp|Q9WVR6.1|LAT2_RAT RecName: Full=Large neutral amino acids tra... 39.7 0.062
sp|Q9QXW9.1|LAT2_MOUSE RecName: Full=Large neutral amino acids t... 39.3 0.084
sp|Q8DHB0.1|KUP_THEEB RecName: Full=Probable potassium transport... 38.9 0.11
sp|Q9N1Q4.1|LAT2_RABIT RecName: Full=Large neutral amino acids t... 38.9 0.14
sp|Q5RAE3.2|LAT2_PONAB RecName: Full=Large neutral amino acids t... 37.7 0.24
sp|Q9UHI5.1|LAT2_HUMAN RecName: Full=Large neutral amino acids t... 37.7 0.25
sp|Q2K2I9.1|KUP3_RHIEC RecName: Full=Probable potassium transpor... 36.6 0.61
sp|Q9ZCD6.1|Y821_RICPR RecName: Full=Uncharacterized protein RP8... 35.4 1.5
sp|Q0AIM8.1|KUP_NITEC RecName: Full=Probable potassium transport... 35.0 2.2
sp|Q17CE7.1|S35B3_AEDAE RecName: Full=Adenosine 3'-phospho 5'-ph... 34.7 2.3
sp|Q2NQ98.1|KUP_SODGM RecName: Full=Low affinity potassium trans... 34.7 2.4
sp|P0C5Y8.1|ALS2_RAT RecName: Full=Alsin; AltName: Full=Amyotrop... 34.3 3.7
sp|B0BNA1.1|SH3Y1_RAT RecName: Full=SH3 domain-containing YSC84-... 33.1 6.3
sp|O08641.1|SH3Y1_MOUSE RecName: Full=SH3 domain-containing YSC8... 33.1 6.7
sp|Q9VVD9.2|S35B3_DROME RecName: Full=Adenosine 3'-phospho 5'-ph... 33.1 7.5
sp|A7MKK9.1|CYSG2_CROS8 RecName: Full=Siroheme synthase 2; Inclu... 32.7 9.6
>sp|P96589.1|YDAO_BACSU RecName: Full=Uncharacterized amino acid permease YdaO
Length=607
Score = 374 bits (959), Expect = 3e-119, Method: Compositional matrix adjust.
Identities = 226/595 (38%), Positives = 346/595 (58%), Gaps = 21/595 (4%)
Query 7 LLGHPLLRKKVDDERLPSVQALPILSSDALSSVAYATEAALGVLILGGSGALGLSVPITL 66
L+G PL + +++L ++AL +LSSDALSSVAY TE L +L + A S+PI +
Sbjct 9 LIGKPLKSQAAGEQKLTKLKALAMLSSDALSSVAYGTEQILIILATISAAAFWYSIPIAV 68
Query 67 AIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVGLIAAAALLIDYTLTAGVSLMA 126
++ L+ ++LSYRQ I AYP+GGG+Y+V+++NLG GLIA +LL+DY LT VS+ A
Sbjct 69 GVLILLLALILSYRQIIYAYPQGGGAYIVSKENLGEKPGLIAGGSLLVDYILTVAVSISA 128
Query 127 GTQALSSLVPSMLDHEVSLALLLLALIGWANLRGLKETGRLFSLPTYAFVVMVALLILAG 186
GT A++S P++ D+ V +A+ L+ +I NLRGL E+ + + P Y FVV + +LI G
Sbjct 129 GTDAITSAFPALHDYHVPIAIFLVLVIMILNLRGLSESASILAYPVYLFVVALLVLIAVG 188
Query 187 LKDLIFEHGFVPDMPPAV-QAVQPLGWFLILRAFSSGCSAMTGIESIANGVKVFQEPAVV 245
L L+ P ++ V + FL+L+AFSSGCSA+TG+E+I+N + F+ P
Sbjct 189 LFKLMTGQIDQPAHHTSLGTPVAGITLFLLLKAFSSGCSALTGVEAISNAIPAFKNPPAR 248
Query 246 NARRTLLVMGVLLAAMFLAVSGLGYMYGIAPNDRVTVLAQIGSRAFGSGSVLLWALQLST 305
NA RTL +MG+LLA +F ++ L Y YG AP TV++QI S FG +V + +Q T
Sbjct 249 NAARTLAMMGILLAILFSGITVLAYGYGTAPKPDETVVSQIASETFGR-NVFYYVIQGVT 307
Query 306 LLILVLAANTAFAGFPRLAAMLAEDHCLPRQLSWIGDRLVYQNGIGVLLLVTALIIVICK 365
LILVLAANT F+ FP+LA LA D +PR + GDRL + NGI L + ++I++
Sbjct 308 SLILVLAANTGFSAFPQLAFNLARDQYMPRMFTVRGDRLGFSNGIIFLGFASIVLIILFG 367
Query 366 GDTTVAVNLYALGVFTAFTLSQLGLVRRWWRLRGNGWQGRLLMNALGAVTTFVVLVVIVV 425
G T + LYA+GVF FTLSQ G+ +W + + GW G++L+N+ GA+ +F+VL ++ V
Sbjct 368 GQTEHLIPLYAVGVFIPFTLSQTGMCMKWIKQKPKGWIGKMLINSCGALISFMVLSILFV 427
Query 426 SKFQEGAWTVVIAIPALVWGLAQIRRRYRKAYAALALEPDFGPLQVEPRQPPLGNHCIVW 485
+KF W V+I +P +V I+ Y L + D P +++ G IV
Sbjct 428 TKFNV-VWPVLIFMPIVVLLFFAIKNHYTAVGEQLRIV-DKEPEEIK------GTVVIVP 479
Query 486 IPGLWRASMEALRYGCSIADSVTAVFVLGDDDDPDAIRTAWDRLVGDHPGELELRLLESH 545
+ G+ +++ Y S++D V AV V D + W+ L + L L S
Sbjct 480 VAGVTTVVQKSIHYAKSLSDQVIAVHVSFDREQEKKFEKRWEELNNG----VRLVTLHSS 535
Query 546 FSSVIDPFCDYVVEQEELHPERTTTVVMAL----VITRDWLDQTLLNQRAVYLFK 596
+ S++ PF D +E E ++ VM L + + W T+L+ ++ +L +
Sbjct 536 YRSLVHPF-DKFLETVEAKAKKEQFSVMVLFPQFITKKRW--HTILHNQSAFLLR 587
>sp|P0AA48.1|PLAP_ECO57 RecName: Full=Low-affinity putrescine importer PlaP
sp|P0AA47.1|PLAP_ECOLI RecName: Full=Low-affinity putrescine importer PlaP
Length=452
Score = 54.3 bits (129), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 48/364 (13%)
Query 55 SGALGLSVPITLAIIALVAIVV--LSYRQAIEAYPKGGGSYVVARDNLGRNVGLIAAAAL 112
SG VP A AL+AI+ LSY + + YP G +Y A+ ++ VG + +
Sbjct 44 SGLTDGHVPTAYAF-ALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS 102
Query 113 LIDYTLTAGVSLMAGTQALSSLVPSMLDHEVSLALLLLALIGWANLRGLKETGRLFSLPT 172
L+DY ++++ +LVPS+ +A L+A + NLR LK F+
Sbjct 103 LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVA--LVAFMTAFNLRSLKSVAN-FNTVI 159
Query 173 YAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSSG---------- 222
V++ +IL + +FE + G R F SG
Sbjct 160 VVLQVVLIAVILGMVVYGVFEG-------------EGAGTLASTRPFWSGDAHVIPMITG 206
Query 223 ----CSAMTGIESIANGVKVFQEPAVVNARRTLLV-----MGVLLAAMFLAVSGLGYMYG 273
C + TG + I+N + ++ V R L M + A FL +
Sbjct 207 ATILCFSFTGFDGISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRF 266
Query 274 IAPN-DRVTVLAQIGSRAFGSGSVLLWALQLSTLLILVLAANTAFAGFPRLAAMLAEDHC 332
P+ + ++ + +AF G AL ST+ +L + A AG RL ++ D
Sbjct 267 KDPDASQPEIMLYVAGKAFQVG-----ALIFSTITVLA-SGMAAHAGVARLMYVMGRDGV 320
Query 333 LPRQ-LSWIGDRLVYQNGIGVLLLVTALIIVICKGDTTVAVNLYALGVFTAFTLSQLGLV 391
P+ ++ + ++ ++LV A+ ++ D +A L G AFT L ++
Sbjct 321 FPKSFFGYVHPK--WRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVI 378
Query 392 RRWW 395
++W
Sbjct 379 SQFW 382
>sp|P76037.2|PUUP_ECOLI RecName: Full=Putrescine importer PuuP
Length=461
Score = 47.8 bits (112), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 92/413 (22%), Positives = 168/413 (41%), Gaps = 54/413 (13%)
Query 69 IALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVGLIAAAALLIDYTLTAGVSLMAGT 128
+A V +SY + + +P+ G +Y A+ ++ +VG + + L+DY ++++
Sbjct 63 LAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMVGWSSLLDYLFLPMINVLLAK 122
Query 129 QALSSLVPSMLDHEVSLALLLLALIGWANLRGLK---ETGRLFSLPTYAFVVMVALLILA 185
LS+L P + + +A++ ANL+ + LF L + +V+ L++
Sbjct 123 IYLSALFPEV--PPWVWVVTFVAILTAANLKSVNLVANFNTLFVLVQISIMVVFIFLVVQ 180
Query 186 GLKDLIFEH-----GFVPDMPPAVQAVQPLGWFLILRAFSSGCSAMTGIESIANGVKVFQ 240
GL H G V + P + L I+ + C + G +++ +
Sbjct 181 GL------HKGEGVGTVWSLQPFISENAHL--IPIITGATIVCFSFLGFDAVTTLSEETP 232
Query 241 EPAVVNARRTLLVMGVLLAAMFLAVSGLGYMYGIAPN-----DRVTVLAQIGSRAFGSGS 295
+ A V + + + V +F+A S +M P+ D L +I A G
Sbjct 233 DAARV-IPKAIFLTAVYGGVIFIAASF--FMQLFFPDISRFKDPDAALPEI---ALYVGG 286
Query 296 VLLWALQLSTLLILVLAANTA-FAGFPRLAAMLAEDHCLP-RQLSWIGDRLVYQNGIGVL 353
L ++ L T + LA+ A A RL ++ D+ P R ++ + ++ +
Sbjct 287 KLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVHPK--WRTPALNV 344
Query 354 LLVTALIIVICKGDTTVAVNLYALGVFTAFTLSQLGLVRRWWRLRG--NGWQGR---LLM 408
++V + + D A L G AFT L + +WR +G W+ LLM
Sbjct 345 IMVGIVALSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMNKSWKDHFHYLLM 404
Query 409 NALGAVTTFVVLVVIVVSKFQEGAWTVVIAIPALVWG------LAQIRRRYRK 455
+GA+T V+ V + + G LVW L + RRYRK
Sbjct 405 PLVGALTVGVLWVNLESTSLTLG----------LVWASLGGAYLWYLIRRYRK 447
>sp|P63116.1|AAA1_RAT RecName: Full=Asc-type amino acid transporter 1; Short=Asc-1;
AltName: Full=D-serine transporter; AltName: Full=Solute carrier
family 7 member 10
sp|P63115.1|AAA1_MOUSE RecName: Full=Asc-type amino acid transporter 1; Short=Asc-1;
AltName: Full=D-serine transporter; AltName: Full=Solute carrier
family 7 member 10
Length=530
Score = 41.6 bits (96), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 84/361 (23%), Positives = 150/361 (42%), Gaps = 27/361 (7%)
Query 51 ILGGSGALGLSVPITLAIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVG--LIA 108
+L SG++GL++ + + + A+ L Y + A PK GG Y + G G L+
Sbjct 71 VLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLW 130
Query 109 AAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHEVS---LALLLLALIGWANLRGLKETG 165
+A L++ T A +S+ L + P+ + + L++ L L+ W N ++
Sbjct 131 SAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWAT 190
Query 166 RLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQA--VQPLGWFLILRAFSSGC 223
R+ + T ++ ++L+I G IF+ F P A + P L L AF G
Sbjct 191 RIQVIFTGGKLLALSLIITVGFVQ-IFQGHFEELRPTNAFAFWMTPSVGHLAL-AFLQGS 248
Query 224 SAMTGIESIANGVKVFQEPAVVNARRTL---LVMGVLLAAMFLAVSGLGYMYGIAPNDRV 280
A +G + + +V+ R+ L + + + L + + Y ++P + +
Sbjct 249 FAFSGWNFLN-----YVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELL 303
Query 281 T---VLAQIGSRAFGSGSVLLWALQLSTLLILVLAANTAFAGFPRLAAMLAEDHCLPRQL 337
+ V G + G S W + +S L N RL A + LP L
Sbjct 304 SSNAVAVTFGEKLLGYFS---WVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFL 360
Query 338 SWIGDRLVYQNGIGVLLLVT-ALIIVICKGDTTVAVNLYALGVFTAFTLSQLG-LVRRWW 395
+ I R I LL+ A +++ GDT +N + + + ++ LG LV RW
Sbjct 361 AMIHVRRC--TPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLVLRWR 418
Query 396 R 396
R
Sbjct 419 R 419
>sp|Q9NS82.1|AAA1_HUMAN RecName: Full=Asc-type amino acid transporter 1; Short=Asc-1;
AltName: Full=Solute carrier family 7 member 10
Length=523
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 81/337 (24%), Positives = 143/337 (42%), Gaps = 26/337 (8%)
Query 51 ILGGSGALGLSVPITLAIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVG--LIA 108
+L SG++GL++ + + + A+ L Y + A PK GG Y + G G L+
Sbjct 65 VLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLW 124
Query 109 AAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHEVS---LALLLLALIGWANLRGLKETG 165
+A L++ T A +S+ L + P+ + + L++ L L+ W N ++
Sbjct 125 SAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWAT 184
Query 166 RLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQA--VQPLGWFLILRAFSSGC 223
R+ + T ++ ++L+I GL IF+ F P A + P L L AF G
Sbjct 185 RIQDMFTGGKLLALSLIIGVGLLQ-IFQGHFEELRPSNAFAFWMTPSVGHLAL-AFLQGS 242
Query 224 SAMTGIESIANGVKVFQEPAVVNARRTL---LVMGVLLAAMFLAVSGLGYMYGIAPNDRV 280
A +G N + E +V+AR+ L + + + L + + Y ++P + +
Sbjct 243 FAFSGW----NFLNYVTE-EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELL 297
Query 281 T---VLAQIGSRAFGSGSVLLWALQLSTLLILVLAANTAFAGFPRLAAMLAEDHCLPRQL 337
+ V G + G S W + +S L N + RL A + LP L
Sbjct 298 SSNAVAVTFGEKLLGYFS---WVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLL 354
Query 338 SWIGDRLVYQNGIGVLLLVT-ALIIVICKGDTTVAVN 373
+ I R + I LL+ A +++ GDT +N
Sbjct 355 AMIHVR--HCTPIPALLVCCGATAVIMLVGDTYTLIN 389
>sp|Q9WVR6.1|LAT2_RAT RecName: Full=Large neutral amino acids transporter small subunit
2; AltName: Full=L-type amino acid transporter 2; AltName:
Full=Solute carrier family 7 member 8
Length=533
Score = 39.7 bits (91), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 68/305 (22%), Positives = 121/305 (40%), Gaps = 26/305 (9%)
Query 51 ILGGSGALGLSVPITLAIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVGLIA-- 108
+L +G++GL++ + + + A+ L Y + PK GG Y +D G G +
Sbjct 66 VLENAGSVGLALIVWIVTGVITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLW 125
Query 109 AAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHE---VSLALLLLALIGWANLRGLKETG 165
A L+I T A ++L L L P+ E LA + L L+ W N ++
Sbjct 126 IAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWAT 185
Query 166 RLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSSGCSA 225
R+ + T ++ +AL+I+ G+ + F + A + Q L+ AF G A
Sbjct 186 RVQDIFTAGKLLALALIIIMGVVQICKGEFFWLEPKNAFENFQEPDIGLVALAFLQGSFA 245
Query 226 MTGIESIANGVKVFQEPAVVNARRTLLVMGVLLAAMFLAVSGLGYMYGIAPNDRV---TV 282
G + + +P N R + + + L + + Y+ ++P + + V
Sbjct 246 YGGWNFLNYVTEELVDP-YKNLPRAIFI-SIPLVTFVYVFANIAYVTAMSPQELLASNAV 303
Query 283 LAQIGSRAFGSGSVLLWALQLSTLLILVLAANTA--------FAG-----FPRLAAMLAE 329
G + G V+ W + +S L N + FAG P + AM+
Sbjct 304 AVTFGEKLLG---VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHV 360
Query 330 DHCLP 334
C P
Sbjct 361 KRCTP 365
>sp|Q9QXW9.1|LAT2_MOUSE RecName: Full=Large neutral amino acids transporter small subunit
2; AltName: Full=L-type amino acid transporter 2; Short=mLAT2;
AltName: Full=Solute carrier family 7 member 8
Length=531
Score = 39.3 bits (90), Expect = 0.084, Method: Compositional matrix adjust.
Identities = 68/305 (22%), Positives = 121/305 (40%), Gaps = 26/305 (9%)
Query 51 ILGGSGALGLSVPITLAIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVGLIA-- 108
+L +G++GL++ + + + A+ L Y + PK GG Y +D G G +
Sbjct 64 VLENAGSVGLALIVWIVTGIITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLW 123
Query 109 AAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHE---VSLALLLLALIGWANLRGLKETG 165
A L+I T A ++L L L P+ E LA + L L+ W N ++
Sbjct 124 IAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWAT 183
Query 166 RLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSSGCSA 225
R+ + T ++ +AL+I+ G+ + F + A + Q L+ AF G A
Sbjct 184 RVQDIFTAGKLLALALIIIMGIVQICKGEFFWLEPKNAFENFQEPDIGLVALAFLQGSFA 243
Query 226 MTGIESIANGVKVFQEPAVVNARRTLLVMGVLLAAMFLAVSGLGYMYGIAPNDRV---TV 282
G + + +P N R + + + L + + Y+ ++P + + V
Sbjct 244 YGGWNFLNYVTEELVDP-YKNLPRAIFI-SIPLVTFVYVFANIAYVTAMSPQELLASNAV 301
Query 283 LAQIGSRAFGSGSVLLWALQLSTLLILVLAANTA--------FAG-----FPRLAAMLAE 329
G + G V+ W + +S L N + FAG P + AM+
Sbjct 302 AVTFGEKLLG---VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHV 358
Query 330 DHCLP 334
C P
Sbjct 359 KRCTP 363
>sp|Q8DHB0.1|KUP_THEEB RecName: Full=Probable potassium transport system protein kup
Length=625
Score = 38.9 bits (89), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 78/177 (44%), Gaps = 27/177 (15%)
Query 9 GHPLLRKKVDDERLPSVQALPILSSDALSSVAYATEAA---LGVLILGGSGALGLSVPIT 65
GHP RL + AL ++ D +S YA E L VL + + G+ ++
Sbjct 7 GHP-------PSRLLMLGALGVVYGDLGTSPLYAFEETFNPLHVLAVTPANIYGI---LS 56
Query 66 LAIIALVAIVVLSYRQ-AIEAYPKGGG------SYVVARDNLGRN-------VGLIAAAA 111
L + LV I L Y A+ A G G + V++R L + GL+ AA
Sbjct 57 LILWGLVLIPTLKYATFALRADNDGEGGIFPLMALVLSRIRLSSHWRRRVIIFGLVGAAM 116
Query 112 LLIDYTLTAGVSLMAGTQALSSLVPSMLDHEVSLALLLLALIGWANLRGLKETGRLF 168
D T+T +S+++ + L L P + V L +++L + W RG + G++F
Sbjct 117 FYGDSTITPAISVLSAIEGLEVLSPQLGSWTVPLTVVILVGLFWFQHRGTTQVGQVF 173
>sp|Q9N1Q4.1|LAT2_RABIT RecName: Full=Large neutral amino acids transporter small subunit
2; AltName: Full=4F2-LC5; AltName: Full=L-type amino acid
transporter 2; AltName: Full=Solute carrier family 7 member
8
Length=535
Score = 38.9 bits (89), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 69/305 (23%), Positives = 120/305 (39%), Gaps = 26/305 (9%)
Query 51 ILGGSGALGLSVPITLAIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVGLIA-- 108
+L +G++GL+V + + + A+ L Y + PK GG Y +D G G +
Sbjct 65 VLENAGSVGLAVIVWIVTGLITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLW 124
Query 109 AAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHE---VSLALLLLALIGWANLRGLKETG 165
A L+I T A ++L L L P+ + LA + L L+ W N ++
Sbjct 125 IAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPDSGLRLLAAICLLLLTWVNCSSVRWAT 184
Query 166 RLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSSGCSA 225
R+ + T ++ +AL+I+ G+ + F + A Q LI AF G A
Sbjct 185 RVQDIFTAGKLLALALIIIMGVVQICKGEYFWLEPKNAFDNFQEPDIGLIALAFLQGSFA 244
Query 226 MTGIESIANGVKVFQEPAVVNARRTLLVMGVLLAAMFLAVSGLGYMYGIAPNDRV---TV 282
G + + +P N R + + + L + + Y+ ++P + + V
Sbjct 245 YGGWNFLNYVTEELVDP-YKNLPRAIFI-SIPLVTFVYVFANVAYITAMSPQELLASNAV 302
Query 283 LAQIGSRAFGSGSVLLWALQLSTLLILVLAANTA--------FAG-----FPRLAAMLAE 329
G + G V+ W + +S L N + FAG P + AM+
Sbjct 303 AVTFGEKLLG---VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHV 359
Query 330 DHCLP 334
C P
Sbjct 360 KRCTP 364
>sp|Q5RAE3.2|LAT2_PONAB RecName: Full=Large neutral amino acids transporter small subunit
2; AltName: Full=L-type amino acid transporter 2; AltName:
Full=Solute carrier family 7 member 8
Length=535
Score = 37.7 bits (86), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 74/308 (24%), Positives = 118/308 (38%), Gaps = 28/308 (9%)
Query 48 GVLILGGSGALGLSVPITLAIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVGLI 107
GVL GS L L V I I +V L Y + PK GG Y +D G G +
Sbjct 64 GVLENAGSVGLALIVWIVTGFITVVG--ALCYAELGVTIPKSGGDYSYVKDIFGGLAGFL 121
Query 108 A--AAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHE---VSLALLLLALIGWANLRGLK 162
A L+I T A ++L L L P+ E LA + L L+ W N ++
Sbjct 122 RLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVR 181
Query 163 ETGRLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSSG 222
R+ + T ++ +AL+I+ G+ + F + A + Q L+ AF G
Sbjct 182 WATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQG 241
Query 223 CSAMTGIESIANGVKVFQEPAVVNARRTLLVMGVLLAAMFLAVSGLGYMYGIAPNDRV-- 280
A G + + +P N R + + + L + + Y+ ++P + +
Sbjct 242 SFAYGGWNFLNYVTEELVDP-YKNLPRAIFI-SIPLVTFVYVFANVAYVTAMSPQELLAS 299
Query 281 -TVLAQIGSRAFGSGSVLLWALQLSTLLILVLAANTA--------FAG-----FPRLAAM 326
V G + G V+ W + +S L N + FAG P + AM
Sbjct 300 NAVAVTFGEKLLG---VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM 356
Query 327 LAEDHCLP 334
+ C P
Sbjct 357 IHVKRCTP 364
>sp|Q9UHI5.1|LAT2_HUMAN RecName: Full=Large neutral amino acids transporter small subunit
2; AltName: Full=L-type amino acid transporter 2; Short=hLAT2;
AltName: Full=Solute carrier family 7 member 8
Length=535
Score = 37.7 bits (86), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 74/308 (24%), Positives = 118/308 (38%), Gaps = 28/308 (9%)
Query 48 GVLILGGSGALGLSVPITLAIIALVAIVVLSYRQAIEAYPKGGGSYVVARDNLGRNVGLI 107
GVL GS L L V I I +V L Y + PK GG Y +D G G +
Sbjct 64 GVLENAGSVGLALIVWIVTGFITVVG--ALCYAELGVTIPKSGGDYSYVKDIFGGLAGFL 121
Query 108 A--AAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHE---VSLALLLLALIGWANLRGLK 162
A L+I T A ++L L L P+ E LA + L L+ W N ++
Sbjct 122 RLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVR 181
Query 163 ETGRLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSSG 222
R+ + T ++ +AL+I+ G+ + F + A + Q L+ AF G
Sbjct 182 WATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQG 241
Query 223 CSAMTGIESIANGVKVFQEPAVVNARRTLLVMGVLLAAMFLAVSGLGYMYGIAPNDRV-- 280
A G + + +P N R + + + L + + Y+ ++P + +
Sbjct 242 SFAYGGWNFLNYVTEELVDP-YKNLPRAIFI-SIPLVTFVYVFANVAYVTAMSPQELLAS 299
Query 281 -TVLAQIGSRAFGSGSVLLWALQLSTLLILVLAANTA--------FAG-----FPRLAAM 326
V G + G V+ W + +S L N + FAG P + AM
Sbjct 300 NAVAVTFGEKLLG---VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM 356
Query 327 LAEDHCLP 334
+ C P
Sbjct 357 IHVKRCTP 364
>sp|Q2K2I9.1|KUP3_RHIEC RecName: Full=Probable potassium transport system protein kup
3
Length=632
Score = 36.6 bits (83), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 30/101 (30%), Positives = 52/101 (51%), Gaps = 7/101 (7%)
Query 104 VGLIAAAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHEVSLALLLLALIGWANLRGLKE 163
+GL+ AA L D +T +S+++ + L + PS+ D+ V +++++LAL+ RG
Sbjct 112 LGLMGAALFLGDAMITPALSVLSAVEGLKLVTPSLSDYIVPISVVILALLFVVQSRGTGA 171
Query 164 TGRLFSLPTYA--FVVMVALLILAGLKDLIFEHGFVPDMPP 202
R F P A F+VM A AG+ + + G + P
Sbjct 172 VARFFG-PITAVWFLVMAA----AGISHISDDFGILAAFNP 207
>sp|Q9ZCD6.1|Y821_RICPR RecName: Full=Uncharacterized protein RP821
Length=492
Score = 35.4 bits (80), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 24/39 (62%), Gaps = 0/39 (0%)
Query 361 IVICKGDTTVAVNLYALGVFTAFTLSQLGLVRRWWRLRG 399
IV+ KG T V+ Y LG++ +S+ L+ RW +LRG
Sbjct 163 IVVTKGPTKDRVDHYNLGIYRMQVVSENKLLMRWLKLRG 201
>sp|Q0AIM8.1|KUP_NITEC RecName: Full=Probable potassium transport system protein kup
Length=641
Score = 35.0 bits (79), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 26/90 (29%), Positives = 43/90 (48%), Gaps = 4/90 (4%)
Query 102 RNV----GLIAAAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHEVSLALLLLALIGWAN 157
RNV GL AA L D +T +S+++ + L P + + + ++L L+
Sbjct 118 RNVLIVLGLFGAALLYGDGMITPAISVLSAMEGLEVAAPQLTSYIIPATTVILVLLFMVQ 177
Query 158 LRGLKETGRLFSLPTYAFVVMVALLILAGL 187
RG GR+F + V++ALL L G+
Sbjct 178 KRGTARIGRVFGPIMLVWFVVIALLGLNGI 207
>sp|Q17CE7.1|S35B3_AEDAE RecName: Full=Adenosine 3'-phospho 5'-phosphosulfate transporter
2; AltName: Full=PAPS transporter 2; AltName: Full=Solute
carrier family 35 member B3 homolog
Length=382
Score = 34.7 bits (78), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 49/110 (45%), Gaps = 4/110 (4%)
Query 162 KETGRLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSS 221
KE LF TY LL AG+ L +G++ ++ + +P GWFL L F
Sbjct 36 KEVKILFFDLTYYNTTTKFLLCCAGVFVLYLLYGYMQELIFTLDGFKPYGWFLTLVQF-- 93
Query 222 GCSAMTGIESIANGVKVFQEPAVVNARRTLLVMGVLLAAMFLAVSGLGYM 271
+ T + ++ + P + + +L+ + L M L+ S LGY+
Sbjct 94 --AYYTVFGYVERSLESKRVPRCIPMKTYVLLAFLTLGTMGLSNSSLGYL 141
>sp|Q2NQ98.1|KUP_SODGM RecName: Full=Low affinity potassium transport system protein
kup; AltName: Full=Kup system potassium uptake protein
Length=622
Score = 34.7 bits (78), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 0/66 (0%)
Query 104 VGLIAAAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHEVSLALLLLALIGWANLRGLKE 163
+GLI + + +T VS+M+ + L + PS+ + V L++++L L+ + +G
Sbjct 105 IGLIGGSFFYGEVVITPAVSVMSAIEGLQIVAPSLQEFIVPLSVVVLTLLFFIQKKGTGS 164
Query 164 TGRLFS 169
G+LF+
Sbjct 165 VGKLFA 170
>sp|P0C5Y8.1|ALS2_RAT RecName: Full=Alsin; AltName: Full=Amyotrophic lateral sclerosis
2 protein homolog
Length=1651
Score = 34.3 bits (77), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 23/86 (27%), Positives = 39/86 (45%), Gaps = 0/86 (0%)
Query 2 SFFQKLLGHPLLRKKVDDERLPSVQALPILSSDALSSVAYATEAALGVLILGGSGALGLS 61
++ QKL H + +E+LP VQ L + L S + +AL L++ + A+G+
Sbjct 341 AYLQKLSEHSVKENHEREEKLPQVQPLVEEAVPDLHSPPTTSTSALNSLVVSCASAVGVR 400
Query 62 VPITLAIIALVAIVVLSYRQAIEAYP 87
V T AL V+++ P
Sbjct 401 VAATYEAGALSLKKVMNFYSTAPCEP 426
>sp|B0BNA1.1|SH3Y1_RAT RecName: Full=SH3 domain-containing YSC84-like protein 1
Length=340
Score = 33.1 bits (74), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 24/63 (38%), Positives = 37/63 (59%), Gaps = 12/63 (19%)
Query 74 IVVLSYRQAIEAYPKG-----GGSYVVARDNLGR----NVGLIAAAALLI---DYTLTAG 121
+++L+Y +A+EA+ KG GG++ VA LGR NV L ++AA+ L AG
Sbjct 102 VIILNYDRAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAG 161
Query 122 VSL 124
+SL
Sbjct 162 ISL 164
>sp|O08641.1|SH3Y1_MOUSE RecName: Full=SH3 domain-containing YSC84-like protein 1
Length=340
Score = 33.1 bits (74), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 24/63 (38%), Positives = 37/63 (59%), Gaps = 12/63 (19%)
Query 74 IVVLSYRQAIEAYPKG-----GGSYVVARDNLGR----NVGLIAAAALLI---DYTLTAG 121
+++L+Y +A+EA+ KG GG++ VA LGR NV L ++AA+ L AG
Sbjct 102 VIILNYDRAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAG 161
Query 122 VSL 124
+SL
Sbjct 162 ISL 164
>sp|Q9VVD9.2|S35B3_DROME RecName: Full=Adenosine 3'-phospho 5'-phosphosulfate transporter
2; AltName: Full=PAPS transporter 2; AltName: Full=Solute
carrier family 35 member B3 homolog; AltName: Full=dPAPST2
Length=396
Score = 33.1 bits (74), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 11/100 (11%)
Query 181 LLILAGLKDLIFEHGFVPDMPPAVQAVQPLGWFLILRAFSSGCSAMTG-IESIANGVKVF 239
LL AG+ L +G++ ++ V+ +P GWFL L F G G +E G ++
Sbjct 63 LLSCAGVFFLYILYGYLQELIFTVEGFKPYGWFLTLVQF--GYYIGFGLVERRLEGYRIS 120
Query 240 --------QEPAVVNARRTLLVMGVLLAAMFLAVSGLGYM 271
EP + R L++ + L M L+ S LGY+
Sbjct 121 GGSFWNIEPEPRCIPMRTYLILAALTLGTMGLSNSSLGYL 160
>sp|A7MKK9.1|CYSG2_CROS8 RecName: Full=Siroheme synthase 2; Includes: RecName: Full=Uroporphyrinogen-III
C-methyltransferase 2; Short=Urogen III methylase
2; AltName: Full=SUMT 2; AltName: Full=Uroporphyrinogen
III methylase 2; Short=UROM 2; Includes: RecName: Full=Precorrin-2
dehydrogenase 2; Includes: RecName: Full=Sirohydrochlorin
ferrochelatase 2
Length=457
Score = 32.7 bits (73), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 30/122 (25%), Positives = 52/122 (43%), Gaps = 19/122 (16%)
Query 88 KGGGSYVVARDNLGRNVGLIAAAALLIDYTLTAGVSLMAGTQALSSLVPSMLDHEVSLAL 147
KGG ++ R G + + A I +++ G++ +G A + L + D+ S+ L
Sbjct 300 KGGDPFIFGRG--GEELETLCDAG--IPFSVVPGITAASGCSAYAGLPLTHRDYAQSVRL 355
Query 148 LLLAL-----IGWANLRGLKETGRLFSLPTYAFVVMVALLILAGLKDLIFEHGFVPDMPP 202
+ L W NL K+T V + L A +++ + EHG P MP
Sbjct 356 ITGHLKNGGEFDWHNLAAEKQT----------LVFYMGLNQAAAIQEKLIEHGMDPQMPV 405
Query 203 AV 204
A+
Sbjct 406 AL 407
Lambda K H a alpha
0.326 0.140 0.423 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 57387131412
Database: Non-redundant UniProtKB/SwissProt sequences
Posted date: Feb 17, 2016 6:10 AM
Number of letters in database: 173,567,248
Number of sequences in database: 462,819
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40