LOCUS       NZ_ABVG02000008        27404 bp    DNA     linear   CON 10-NOV-2010
DEFINITION  Clostridium thermocellum JW20 ctg275, whole genome shotgun
            sequence.
ACCESSION   NZ_ABVG02000008 NZ_ABVG00000000
VERSION     NZ_ABVG02000008.1  GI:281419513
DBLINK      Project: 55013
KEYWORDS    WGS.
SOURCE      Clostridium thermocellum JW20
  ORGANISM  Clostridium thermocellum JW20
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (bases 1 to 27404)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Saunders,E., Brettin,T., Detter,J.C., Han,C., Bruce,D., Goodwin,L.,
            Pitluck,S., Larimer,F., Land,M.L., Hauser,L., Kyrpides,N.,
            Mikhailova,N., Hemme,C.L., He,Q., Wiegel,J., Tanner,R., Lynd,L.,
            Lawson,P., Fields,M.W., He,Z., Arkin,A., Schadt,C., Stevenson,B.S.,
            McInerney,M., Yang,Y., Dong,H., Huhnke,R., Mielenz,J.R.,
            Ding,S.-Y., Himmel,M., Taghavi,S., van der Lelie,D. and Zhou,J.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF) and the Clostridium
            Sequencing Consortium
  TITLE     The draft genome of Clostridium thermocellum JW20
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27404)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Saunders,E., Brettin,T., Detter,J.C., Han,C., Bruce,D., Goodwin,L.,
            Pitluck,S., Larimer,F., Land,M.L., Hauser,L., Kyrpides,N.,
            Mikhailova,N. and Hemme,C.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2009) US DOE Joint Genome Institute, 2800
            Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
REFERENCE   3  (bases 1 to 27404)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L.,
            Hauser,L. and Hemme,C.L.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUL-2008) US DOE Joint Genome Institute, 2800
            Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     PREDICTED REFSEQ: This record has not been reviewed and the
            function is unknown. The reference sequence was derived from
            ABVG02000008.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4043105
            Source DNA available from Christopher L. Hemme (hemmecl@ou.edu)
            Organism available from DSMZ: DSM 4150
            Contacts: Christopher L. Hemme (hemmecl@ou.edu)
              Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            We are labeling this project as Permanent Draft. No further work is
            planned for this project at this time.
            
            ##Metadata-START##
            Organism Display Name :: Clostridium thermocellum JW 20, DSM 4150
            Culture Collection ID :: DSM 2360, ATCC 31549
            GOLD Stamp ID         :: Gi02003
            Isolation Site        :: cotton bale in Louisiana
            Isolation Country     :: USA
            Oxygen Requirement    :: Anaerobe
            Cell Shape            :: Rod-shaped
            Motility              :: Motile
            Sporulation           :: Sporulating
            Temperature Range     :: Thermophile
            Temperature Optimum   :: 60C
            Gram Staining         :: gram+
            Biotic Relationship   :: Free living
            Diseases              :: None
            Energy Source         :: Chemoorganotroph
            ##Metadata-END##
FEATURES             Location/Qualifiers
     source          1..27404
                     /organism="Clostridium thermocellum JW20"
                     /mol_type="genomic DNA"
                     /strain="JW20"
                     /isolation_source="cotton bale"
                     /db_xref="taxon:492476"
                     /country="USA: Louisiana"
     gene            complement(<1..146)
                     /locus_tag="Cther_0097"
     CDS             complement(<1..146)
                     /locus_tag="Cther_0097"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250527.1"
                     /db_xref="GI:281419514"
                     /translation="MATITLYAGKINQMPGLINEVKKSVVDYKSELSALRKKTLNINR
                     TEVYA"
     gene            complement(289..446)
                     /locus_tag="Cther_0098"
                     /pseudo
     gene            complement(542..1347)
                     /locus_tag="Cther_0099"
                     /pseudo
     gene            complement(1472..1609)
                     /locus_tag="Cther_0100"
     CDS             complement(1472..1609)
                     /locus_tag="Cther_0100"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: cbb:CLD_2459 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250528.1"
                     /db_xref="GI:281419515"
                     /translation="MSKKKYIVRCPHCNHRVFDADYADVEIKCPVCRKVFEVKLEKKA
                     G"
     gene            complement(1602..1991)
                     /locus_tag="Cther_0101"
     CDS             complement(1602..1991)
                     /locus_tag="Cther_0101"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250529.1"
                     /db_xref="GI:281419516"
                     /translation="MSTEKDSMLRVRLTQRQSDELDAIIGELQAQMPEASVTTSSIAR
                     YALEKYVSDHIAKRDGTKIFIEINTADATEEDIKNLYDLLSKLFDETKENYSPMVHYM
                     VGEILEPLMMKMARLMKLKKPEVKANE"
     gene            complement(2177..2617)
                     /locus_tag="Cther_0102"
     CDS             complement(2177..2617)
                     /locus_tag="Cther_0102"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: gau:GAU_3372 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250530.1"
                     /db_xref="GI:281419517"
                     /translation="MPSFDTDFQNAKGNPVKYKNLELIRVDRIPVKRGITGWLKVIST
                     NSEWKQGIRIKIDGLMSINSCEGNDFIIWADDVDGDVPFKVISGKTLMVWNAWDTGGG
                     RVDAWLNGAAMILEINGKSRRYKCNDSHPDENFDDIIFEVVINE"
     gene            complement(2622..2942)
                     /locus_tag="Cther_0103"
                     /pseudo
     mobile_element  complement(2954..4348)
                     /mobile_element_type="insertion sequence:ISCth6 element
                     like, family IS110"
     gene            complement(3059..4282)
                     /locus_tag="Cther_0104"
     CDS             complement(3059..4282)
                     /locus_tag="Cther_0104"
                     /inference="protein motif:PFAM:PF02371"
                     /note="PFAM: transposase IS116/IS110/IS902 family protein;
                     transposase IS111A/IS1328/IS1533;
                     KEGG: bcx:BCA_2283 transposase, IS110 family, OrfB"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS110 family protein"
                     /protein_id="ZP_06250531.1"
                     /db_xref="GI:281419518"
                     /db_xref="InterPro:IPR002525"
                     /db_xref="InterPro:IPR003346"
                     /translation="MYHKRNTCFVGIDMHKDAHCAVVIDCWMNKLGEVNFENRPSRFP
                     AFVEDVRKICGIKEIVFGLEDTRGFGRNLAAYLVGRKFEVKHVNPAYTSAVRLANPII
                     YKDDSYDAYCVARVLRDMVDTLQDAKHEDIFWTIRQMVKRRDLIVKSNVMNKNQLHSQ
                     LAYSYPSYRKFFAMVDSKSALCFWENYPSPEYIWNTTPEEIYQTIKPVHQALKIQRIH
                     EIISMIERDGDTRKDYQPERDFIVRNIVKDIRNKKELIAEIDDELRKLIPLTGYKLHT
                     MPGIDLVTEVQIISEIGDINRFPDSDKLARFMGLAPVQFSSAGKGKDQRCRNGNRALN
                     AIFHFLAIQMVAVSASGKPRHPVFREYFEQKVKEGKNKPQALVCVARRLVRIIYGMMK
                     TRIEYRPFEKADDKN"
     misc_feature    complement(3764..4054)
                     /locus_tag="Cther_0104"
                     /note="Transposase; Region: Transposase_9; pfam01548"
                     /db_xref="CDD:144952"
     misc_feature    complement(3194..3463)
                     /locus_tag="Cther_0104"
                     /note="Transposase IS116/IS110/IS902 family; Region:
                     Transposase_20; pfam02371"
                     /db_xref="CDD:145490"
     gene            complement(4669..5034)
                     /locus_tag="Cther_0105"
     CDS             complement(4669..5034)
                     /locus_tag="Cther_0105"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250532.1"
                     /db_xref="GI:281419519"
                     /translation="MVQSDECYCGIKALTVGRGESVRAKITTTIEEALLNKAKALAKQ
                     EGLSGANAIIERALELYFTSIQSEVWEKSLSSGWIKKLVLKGDSILYENIKCRKTLEN
                     CRPEDYTQERLKAKGWKKV"
     gene            complement(5197..6510)
                     /locus_tag="Cther_0106"
     CDS             complement(5197..6510)
                     /locus_tag="Cther_0106"
                     /inference="protein motif:PFAM:PF05065"
                     /note="PFAM: major capsid protein HK97;
                     KEGG: dat:HRM2_48020 phage major capsid protein, HK97
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein HK97"
                     /protein_id="ZP_06250533.1"
                     /db_xref="GI:281419520"
                     /db_xref="InterPro:IPR006444"
                     /translation="MRFIADLVHEKKQLVEKAEAILNEAEKAGGSLTKEQERQFNRYT
                     DKIKSINESIDEELLNIRTSEPILNMPQKAVSPVEETKTPVTKAISKSFRGMFYGNET
                     VKLSNNGFHSMDEFLRTLHSGRADNRLINASMVEGIPEFGGYSVPEEYGAFLMDKSLE
                     NEIIRPRATVWAMGSETKKVPAFDGADRTNNLFGGISGEWLEEGQTGTRKTAKLRLIQ
                     LKAKKLACFSQASNELIADGMSFEEMLAGALIKGLGWYMDYAFINGTGEGQPLGIIND
                     PALITVNKEDSQAAATITYQNVVNMFSRLAPSCFTNAVWLANPSVIPQLLTMTITIGT
                     GGAQIPVFREESGKFTLLGKEVLFTEKCPALGAKGDLILADLSQYAIGMRKEIALDRS
                     NVPGWMEDMTDYRVIVRVDGQGTWDKPITPKNGATLSWAVALEAR"
     misc_feature    complement(5275..6501)
                     /locus_tag="Cther_0106"
                     /note="phage major capsid protein, HK97 family; Region:
                     major_cap_HK97; TIGR01554"
                     /db_xref="CDD:162419"
     misc_feature    complement(5251..6087)
                     /locus_tag="Cther_0106"
                     /note="Phage capsid family; Region: Phage_capsid;
                     pfam05065"
                     /db_xref="CDD:147312"
     gene            complement(6781..8940)
                     /locus_tag="Cther_0107"
     CDS             complement(6781..8940)
                     /locus_tag="Cther_0107"
                     /inference="protein motif:TFAM:TIGR01613"
                     /note="TIGRFAM: phage/plasmid primase, P4 family;
                     PFAM: primase P4 ; Bifunctional DNA primase/polymerase ;
                     Primase 1; D5 protein;
                     KEGG: afl:Aflv_0784 phage associated DNA primase"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="ZP_06250534.1"
                     /db_xref="GI:281419521"
                     /db_xref="InterPro:IPR004968"
                     /db_xref="InterPro:IPR006500"
                     /db_xref="InterPro:IPR014015"
                     /db_xref="InterPro:IPR014818"
                     /db_xref="InterPro:IPR014820"
                     /db_xref="InterPro:IPR015330"
                     /translation="MKVTMMDAALKYAEANIPVIPLHWICEDGSCSCKVGSNCDSKGK
                     HPLYTGWYKNSTADVEQIRKWWTKTPYANIGIPTGEKSGWLVLDVDDGGDETISALEA
                     THGKLPDTVTAVTGSGGRHYIFKYPEGRSIPNKTKFAPGLDTRSTGGLIVVAPSIHVS
                     GNRYEWIKDHSPFDRTLAEAPEWLLKLMERVEVLLTPFEGSSIAAEIKEGSRNSTLTS
                     LAGTMRVRGMTEESIYAALLAENNARCNPPLDEAEVKKIAHSVSRYQPNPPMKKHYHR
                     TDSGNAERLRDRFGSIIRYCPAFKYWLVYDGCCWRKETGELMQFAIKTARDMLAEASR
                     IEDEAMRKELVRHAMQSENAGRLKAMIDVASNLEGLVIMPDELDADIWKLNCKNGVVN
                     LKTGELLPHKREYYMSKICPVEYKPSSKAPRWMDFLNTITGGSKELVRYLQKAVGSSL
                     SGDISEQALFVLYGTGANGKSTFLNTISELLGDYARNTPSETFMAKRIEAIGNDIARL
                     QGARLVTAIEINEGQRLSEALIKSFTGGDRITARFLYGEYFDFQPQFTPFLVVNHRPV
                     IRDTSHSIWRRIKLIPFTVTIPEDKKDKQLPAKLREELPGILSWAVEGCLLWQKEGLE
                     MPDEVKEATEGYREEMDTFSSFIEECCIVEEGRKVSNRSIRYAYETWCRENGDYPLGQ
                     KLFNAKMTERGFAVKRSGANGSRDWHGIGLADEGILL"
     misc_feature    complement(8380..8826)
                     /locus_tag="Cther_0107"
                     /note="Prim_Pol: Primase-polymerase (primpol) domain of
                     the type found in bifunctional replicases from archaeal
                     plasmids, including ORF904 protein of the crenarchaeal
                     plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol).
                     These primpol domains belong to the...; Region: Prim_Pol;
                     cd04859"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(8512..8514,8578..8580,8671..8673,
                     8677..8679,8809..8811))
                     /locus_tag="Cther_0107"
                     /note="polymerase nucleotide-binding site; other site"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(8473..8475,8491..8493,8794..8796,
                     8806..8808))
                     /locus_tag="Cther_0107"
                     /note="DNA-binding residues; DNA binding site"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(8491..8493,8512..8514,8578..8580,
                     8584..8589,8596..8598,8671..8673,8677..8679,8716..8718))
                     /locus_tag="Cther_0107"
                     /note="nucleotide binding site; other site"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(8512..8514,8578..8580,8671..8673,
                     8677..8679))
                     /locus_tag="Cther_0107"
                     /note="primase nucleotide-binding site; other site"
                     /db_xref="CDD:80309"
     misc_feature    complement(8149..8334)
                     /locus_tag="Cther_0107"
                     /note="Primase C terminal 1 (PriCT-1); Region: PriCT_1;
                     pfam08708"
                     /db_xref="CDD:149687"
     misc_feature    complement(6805..8112)
                     /locus_tag="Cther_0107"
                     /note="hypothetical protein; Provisional; Region:
                     PRK14709"
                     /db_xref="CDD:173172"
     misc_feature    complement(7642..8097)
                     /locus_tag="Cther_0107"
                     /note="D5 N terminal like; Region: D5_N; pfam08706"
                     /db_xref="CDD:149685"
     misc_feature    complement(6886..7797)
                     /locus_tag="Cther_0107"
                     /note="C-terminal domain; Region: primase_Cterm;
                     TIGR01613"
                     /db_xref="CDD:130674"
     gene            complement(9061..9198)
                     /locus_tag="Cther_0108"
     CDS             complement(9061..9198)
                     /locus_tag="Cther_0108"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: cbb:CLD_2459 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250535.1"
                     /db_xref="GI:281419522"
                     /translation="MSKKKYIVRCPHCNHRVFDADYADAEIKCPVCKKVFEVKLEKKA
                     G"
     gene            complement(9191..9569)
                     /locus_tag="Cther_0109"
                     /pseudo
     gene            complement(9689..10057)
                     /locus_tag="Cther_0110"
     CDS             complement(9689..10057)
                     /locus_tag="Cther_0110"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250536.1"
                     /db_xref="GI:281419523"
                     /translation="MIFDKFTIHKIQDFNLHDAEVAKVICDYNMHRIEIPLKLYKCNN
                     SVKEVTITCEDVQYADISFYEPWGAGIYVDEVSINDGADIINRLVEYQSNNESFCLSI
                     LLNSGDRINILTSKVIYSET"
     gene            complement(10073..10942)
                     /locus_tag="Cther_0111"
     CDS             complement(10073..10942)
                     /locus_tag="Cther_0111"
                     /inference="protein motif:SMART:SM00306"
                     /note="SMART: Hedgehog/intein hint domain protein;
                     KEGG: ate:Athe_2571 transglutaminase domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hedgehog/intein hint domain protein"
                     /protein_id="ZP_06250537.1"
                     /db_xref="GI:281419524"
                     /db_xref="InterPro:IPR003587"
                     /db_xref="InterPro:IPR006141"
                     /translation="MTTALSFSMDGFDMLAMGISLFEPSNALVEFNRKLHSNALYNGF
                     QIAVNALAVFSAGAASTMKCFVAGTMILTVAGLVAIENIKAGDKVIATNPETFEVAEK
                     TVLETYVRETTELLHLTINGEVIKTTFEHPFYVKDVGFVEAGKLQVGDKLVDSRGNVL
                     VVEEKKLEITDKPVKVYNFKVDNFHTYHVGENRVLVHNANKYVKGTSSTVFPEDPKTF
                     NPDGLVRKEYNNGKIIKWHDPKTGKAVYEWNADPKYGNHYHVTPDGKNRIPHPDTGDT
                     HIRPGESVPKINK"
     misc_feature    complement(10349..10753)
                     /locus_tag="Cther_0111"
                     /note="Hedgehog/Intein domain, found in Hedgehog proteins
                     as well as proteins which contain inteins and undergo
                     protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In
                     protein splicing an intervening polypeptide sequence - the
                     intein - is excised from a...; Region: Hint; cd00081"
                     /db_xref="CDD:73181"
     misc_feature    complement(order(10349..10354,10550..10552,10751..10753))
                     /locus_tag="Cther_0111"
                     /note="protein-splicing catalytic site; other site"
                     /db_xref="CDD:73181"
     misc_feature    complement(order(10550..10552,10559..10561,10751..10753))
                     /locus_tag="Cther_0111"
                     /note="thioester formation/cholesterol transfer; other
                     site"
                     /db_xref="CDD:73181"
     misc_feature    complement(10346..10735)
                     /locus_tag="Cther_0111"
                     /note="Protein of unknown function (DUF1557); Region:
                     DUF1557; pfam07591"
                     /db_xref="CDD:148935"
     gene            complement(11156..11773)
                     /locus_tag="Cther_0112"
     CDS             complement(11156..11773)
                     /locus_tag="Cther_0112"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: bcz:BCZK2568 phosphoesterase-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250538.1"
                     /db_xref="GI:281419525"
                     /translation="MIDLIKLEITRTKFIKIYLPCEKKNIKPFDIISIKYLKDQIEYD
                     LYVDDFATEAIQILKNLLKKALNFDLQIQRKYIDKGIGYYYNIYANELWTTDDENVIQ
                     SLVDPSQNFSLWSTPTHIGIETFMYNIDDKIYIEISPIYKWNCDYPENESEYETFDNF
                     LNNYKPIDIVSIDRSVAERWLDFCCDMIKIFKENDKKYLKEDNTN"
     gene            complement(11877..13609)
                     /locus_tag="Cther_0113"
                     /pseudo
     gene            complement(13755..13909)
                     /locus_tag="Cther_0114"
                     /pseudo
     gene            complement(14005..14811)
                     /locus_tag="Cther_0115"
     CDS             complement(14005..14811)
                     /locus_tag="Cther_0115"
                     /inference="protein motif:PFAM:PF09250"
                     /note="PFAM: Bifunctional DNA primase/polymerase ; Primase
                     1;
                     KEGG: ate:Athe_0745 bifunctional DNA primase/polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Bifunctional DNA primase/polymerase"
                     /protein_id="ZP_06250539.1"
                     /db_xref="GI:281419526"
                     /db_xref="InterPro:IPR014820"
                     /db_xref="InterPro:IPR015330"
                     /translation="MKMTMMDAAIKYAEANIPVIPLHWICEDGSCSCKAGSDCDSKGK
                     HPLYTGWYKNSTTDVEQIKKWWTKTPNANIGIPTGEKSGWLVLDVDDGGDETLSALEA
                     THGKLPDTVTAVTGSGGRHYVFIYPKGRSIPNKTKFAPGLDTRSTGGLIAVAPSIHVS
                     GNRYEWIKDHSPFDRTPAEAPAWLLKLMEKEEVLLTPFEGSSIIAEIKEGSRNSTLTS
                     LAGSMRARGMTEEGIYTALLAENNARCNPPLDEAEIKKIYSLGFQRVSSL"
     misc_feature    complement(14263..14697)
                     /locus_tag="Cther_0115"
                     /note="Prim_Pol: Primase-polymerase (primpol) domain of
                     the type found in bifunctional replicases from archaeal
                     plasmids, including ORF904 protein of the crenarchaeal
                     plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol).
                     These primpol domains belong to the...; Region: Prim_Pol;
                     cd04859"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(14383..14385,14449..14451,14542..14544,
                     14548..14550,14680..14682))
                     /locus_tag="Cther_0115"
                     /note="polymerase nucleotide-binding site; other site"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(14344..14346,14362..14364,14665..14667,
                     14677..14679))
                     /locus_tag="Cther_0115"
                     /note="DNA-binding residues; DNA binding site"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(14362..14364,14383..14385,14449..14451,
                     14455..14460,14467..14469,14542..14544,14548..14550,
                     14587..14589))
                     /locus_tag="Cther_0115"
                     /note="nucleotide binding site; other site"
                     /db_xref="CDD:80309"
     misc_feature    complement(order(14383..14385,14449..14451,14542..14544,
                     14548..14550))
                     /locus_tag="Cther_0115"
                     /note="primase nucleotide-binding site; other site"
                     /db_xref="CDD:80309"
     misc_feature    complement(14014..14205)
                     /locus_tag="Cther_0115"
                     /note="Primase C terminal 1 (PriCT-1); Region: PriCT_1;
                     pfam08708"
                     /db_xref="CDD:149687"
     gene            complement(14936..15074)
                     /locus_tag="Cther_0116"
                     /pseudo
     gene            complement(15067..15456)
                     /locus_tag="Cther_0117"
     CDS             complement(15067..15456)
                     /locus_tag="Cther_0117"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250540.1"
                     /db_xref="GI:281419527"
                     /translation="MSTEKDSMLRVRLTQRQSDELDAIVGELQAQMPEASVTTSSIAR
                     YALEKYVSDHIAKRDGTKIFIEVSTGDATDEDIKNLYDLLSRLFDETKENYSPMVHYM
                     VGEILEPVMMKMARLMKLKKPEVKAGE"
     misc_feature    complement(<15202..15432)
                     /locus_tag="Cther_0117"
                     /note="6-phosphogluconate dehydrogenase-like protein;
                     Reviewed; Region: PRK12490"
                     /db_xref="CDD:139015"
     gene            complement(15651..15929)
                     /locus_tag="Cther_0118"
     CDS             complement(15651..15929)
                     /locus_tag="Cther_0118"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250541.1"
                     /db_xref="GI:281419528"
                     /translation="MNDILKQIDNVLHDLGFEVVEINGNKLYHNKNKGSYYRFTFIEA
                     FRAYVIESASNYEEAKNNLFEDGDLFSIDVDEKDFVEKLRADLIKYYC"
     gene            complement(15943..16239)
                     /locus_tag="Cther_0119"
                     /pseudo
     mobile_element  complement(16254..17625)
                     /mobile_element_type="insertion sequence:ISCth14 element
                     like, family IS110"
     gene            complement(16333..17562)
                     /locus_tag="Cther_0120"
     CDS             complement(16333..17562)
                     /locus_tag="Cther_0120"
                     /inference="protein motif:PFAM:PF02371"
                     /note="PFAM: transposase IS116/IS110/IS902 family protein;
                     transposase IS111A/IS1328/IS1533;
                     KEGG: bcx:BCA_2283 transposase, IS110 family, OrfB"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS110 family protein"
                     /protein_id="ZP_06250542.1"
                     /db_xref="GI:281419529"
                     /db_xref="InterPro:IPR002525"
                     /db_xref="InterPro:IPR003346"
                     /translation="MYNKRNICFVGVDMHKEKHCAVVIDCWMEKIGEVNFENKPSKFP
                     AFVEEIRKICGTKDFVFGLEDTRGFGRNLASYLTGRKFEVKHVNPVYTSAIRLSNPII
                     YKDDSYDAYCVARVLRDMVDTLQDAKHEDIYWAIRQLVKRREIIVKYNVMNKNQLHSQ
                     LSYGYPSYKKFFSQIDGKSALCFWENYPSPEHIWCTTPEQIYETIKAVHQAFKIERVH
                     AIIDMIKKDGNTQKGYQEERDTIVRNIVKDIKNNQELLKDIEKQLRKLLPQTGYKLQT
                     MPGIDLITEAKIVSEIGDINRFPNSDKLARFMGLAPVHFSSAGKGKEERCRNGNRELN
                     AIFHFLAIQMVAVSPSGKPRHPVFREYFEQKVKEGKNKPQALICISRTLVRLIYGMMK
                     TKTEYRPYEKKEEEGNN"
     misc_feature    complement(17044..17334)
                     /locus_tag="Cther_0120"
                     /note="Transposase; Region: Transposase_9; pfam01548"
                     /db_xref="CDD:144952"
     misc_feature    complement(16474..16743)
                     /locus_tag="Cther_0120"
                     /note="Transposase IS116/IS110/IS902 family; Region:
                     Transposase_20; pfam02371"
                     /db_xref="CDD:145490"
     gene            complement(18009..18566)
                     /locus_tag="Cther_0121"
     CDS             complement(18009..18566)
                     /locus_tag="Cther_0121"
                     /inference="protein motif:PFAM:PF02796"
                     /note="PFAM: Resolvase helix-turn-helix domain protein;
                     KEGG: mmz:MmarC7_1490 resolvase domain-containing protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Resolvase helix-turn-helix domain protein"
                     /protein_id="ZP_06250543.1"
                     /db_xref="GI:281419530"
                     /db_xref="InterPro:IPR006119"
                     /db_xref="InterPro:IPR006120"
                     /db_xref="InterPro:IPR009057"
                     /translation="MVYAYFIENTGGEFKDNSCLFRYIKEQNISEDNIYIDTADNKDE
                     LDALLENIEPGDAIVLRTVTDLAEKRSELLHLLKELQDFGILIHSIMEPFLNGLEYFD
                     RLQGSIEISKYYAEKKRRLAFEEARKQGVVGRPKIPQEQIETALKLYASKLFTTEEIA
                     KLSGVSSSTLYRALKEQGQLFRIYE"
     misc_feature    complement(18027..18566)
                     /locus_tag="Cther_0121"
                     /note="multiple promoter invertase; Provisional; Region:
                     mpi; PRK13413"
                     /db_xref="CDD:184041"
     misc_feature    complement(18174..18509)
                     /locus_tag="Cther_0121"
                     /note="Serine Recombinase family, catalytic domain; a DNA
                     binding domain may be present either N- or C-terminal to
                     the catalytic domain. These enzymes perform site-specific
                     recombination of DNA molecules by a concerted, four-strand
                     cleavage and rejoining...; Region: Ser_Recombinase;
                     cl02788"
                     /db_xref="CDD:155104"
     misc_feature    complement(18045..18170)
                     /locus_tag="Cther_0121"
                     /note="Helix-turn-helix domain of Hin and related
                     proteins, a family of DNA-binding domains unique to
                     bacteria and represented by the Hin protein of Salmonella.
                     The basic HTH domain is a simple fold comprised of three
                     core helices that form a right-handed...; Region:
                     HTH_Hin_like; cd00569"
                     /db_xref="CDD:119388"
     misc_feature    complement(order(18048..18056,18060..18065,18162..18167))
                     /locus_tag="Cther_0121"
                     /note="DNA-binding interface; DNA binding site"
                     /db_xref="CDD:119388"
     gene            complement(18833..19183)
                     /locus_tag="Cther_0122"
     CDS             complement(18833..19183)
                     /locus_tag="Cther_0122"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250544.1"
                     /db_xref="GI:281419531"
                     /translation="MSKDIRTVRPPVQLLPKAIIAVRPASTAKADLEVMAAQVAQLTT
                     ACCQENIQVDSIIITFGGIKDITKRVKQLTEQKDISYLIIYSGKQIAENESEYVNFKR
                     DMQDWYYLKVVCYR"
     gene            complement(19176..19364)
                     /locus_tag="Cther_0123"
     CDS             complement(19176..19364)
                     /locus_tag="Cther_0123"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250545.1"
                     /db_xref="GI:281419532"
                     /translation="MTGKMTLPLTLDKADIDILRILNKYCYLIMEFKFVTDDMILLDV
                     SAFTNVADAVKREGSNNE"
     gene            complement(20130..20372)
                     /locus_tag="Cther_0124"
     CDS             complement(20130..20372)
                     /locus_tag="Cther_0124"
                     /inference="similar to AA sequence:KEGG:BALH_0941"
                     /note="KEGG: btl:BALH_0941 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250546.1"
                     /db_xref="GI:281419533"
                     /translation="MKKYKCVCCGYYTMESEPPGTFEICPVCFWEDDGVQYEDPDYEG
                     GANGISLNKARENYKKIGAISEKYLENVRKPFNDEI"
     gene            complement(20387..22021)
                     /locus_tag="Cther_0125"
     CDS             complement(20387..22021)
                     /locus_tag="Cther_0125"
                     /inference="protein motif:SMART:SM00306"
                     /note="SMART: Hedgehog/intein hint domain protein;
                     KEGG: ate:Athe_2571 transglutaminase domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hedgehog/intein hint domain protein"
                     /protein_id="ZP_06250547.1"
                     /db_xref="GI:281419534"
                     /db_xref="InterPro:IPR003587"
                     /db_xref="InterPro:IPR006141"
                     /translation="MATITLYAGKINQMPGLINEVKKSVVDYKSELSALRKKTLNINR
                     SVCNLDEVISSIQASSQTQDRKIDSLEKFCSESEKFISEVIRIDEEVAELINKRKENF
                     YKEYYYLKPESEKSGWEKIKDGLKAVAEWCKENWKSIAKIVAAAVVITGLGIAAALTG
                     GILGVILAGAFWGALAGGLIGGAVGGIAAAINGGSFLEGFADGALSGAISGAVTGAAC
                     AGLGALGALAGKSIQCMSTVGKAINVTSKVTAALSFGMDGFDMLAMGISLFDPSNALV
                     EFNRKLHSNALYNGFQIAVNALAVFSAGAASTMKCFVAGTMILTVAGLVAIENIKAGD
                     KVIATNPETFEVAEKTVLETYVRETTELLHLTINGEVIKTTFEHPFYVKDVGFVEAGK
                     LQVGDKLVDSRGNVLVVEEKKLEITDKPVKVYNFKVDNFHTYHVGENRVLVHNANKYV
                     KGTSKAGFKTQELLDSHFKKHAAEFGNITKEQYLKGAQDLVSSKPGGNILTKVRPNGD
                     TIFYNKISNEFAVKTSDGIIRTYFKPTDGINYFNRQ"
     misc_feature    complement(20687..21091)
                     /locus_tag="Cther_0125"
                     /note="Hedgehog/Intein domain, found in Hedgehog proteins
                     as well as proteins which contain inteins and undergo
                     protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In
                     protein splicing an intervening polypeptide sequence - the
                     intein - is excised from a...; Region: Hint; cd00081"
                     /db_xref="CDD:73181"
     misc_feature    complement(order(20687..20692,20888..20890,21089..21091))
                     /locus_tag="Cther_0125"
                     /note="protein-splicing catalytic site; other site"
                     /db_xref="CDD:73181"
     misc_feature    complement(order(20888..20890,20897..20899,21089..21091))
                     /locus_tag="Cther_0125"
                     /note="thioester formation/cholesterol transfer; other
                     site"
                     /db_xref="CDD:73181"
     misc_feature    complement(20684..21073)
                     /locus_tag="Cther_0125"
                     /note="Protein of unknown function (DUF1557); Region:
                     DUF1557; pfam07591"
                     /db_xref="CDD:148935"
     misc_feature    complement(20390..>20686)
                     /locus_tag="Cther_0125"
                     /note="Pyocin large subunit [General function prediction
                     only]; Region: COG5529"
                     /db_xref="CDD:35088"
     gene            complement(22164..22511)
                     /locus_tag="Cther_0126"
     CDS             complement(22164..22511)
                     /locus_tag="Cther_0126"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250548.1"
                     /db_xref="GI:281419535"
                     /translation="MECFALFRSIINELVDENRCKVYDSGREIDFKYYSDNNTLTFTL
                     GKGWHNVGIVLVDMAGNVNNIQEIRNIHVGFFWLWVIAAVSAVLIAAIVAAVIHNIRK
                     RRKEEKENELAAA"
     mobile_element  22923..24435
                     /mobile_element_type="insertion sequence:ISCth4 element
                     like, family IS256"
     gene            22997..24221
                     /locus_tag="Cther_0127"
                     /pseudo
     gene            complement(24494..24964)
                     /locus_tag="Cther_0128"
     CDS             complement(24494..24964)
                     /locus_tag="Cther_0128"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: sew:SeSA_A2876 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250549.1"
                     /db_xref="GI:281419536"
                     /translation="MAMEDIVGIIFEDIEEVKPILSDSEGNDLEGNDLSEAILEYGIS
                     EGKFLCVDYGGEEGSEIINYIMDYEFSHGIELATQEELEELDEMEYDDLTDKIKEVNK
                     ILEKAGYGLFCFPTGSDFYELFIAKLEDKEKLLEEKIVDDEELPLEERYIQYYV"
     gene            complement(24977..25288)
                     /locus_tag="Cther_0129"
     CDS             complement(24977..25288)
                     /locus_tag="Cther_0129"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: xcb:XC_2059 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250550.1"
                     /db_xref="GI:281419537"
                     /translation="MIDKMILYHSVLVSDIDNEPEFGDYTYGFYPYEILFLMHIRRKL
                     GLPVPDKFEDLLMNTPEAKVVINEPEPYPEWDPLLRAIDEFYRKNYPNYIPNKHGKLF
                     E"
     gene            complement(25368..25505)
                     /locus_tag="Cther_0130"
     CDS             complement(25368..25505)
                     /locus_tag="Cther_0130"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_06250551.1"
                     /db_xref="GI:281419538"
                     /translation="MVVNVNIINVNIINVKRYRNRTIAGESQNVHLAVKDKLKKRGAF
                     I"
     gene            complement(25714..26952)
                     /locus_tag="Cther_0131"
     CDS             complement(25714..26952)
                     /locus_tag="Cther_0131"
                     /inference="protein motif:PFAM:PF08928"
                     /note="PFAM: Domain of unknown function DUF1910; Domain of
                     unknown function DUF1911;
                     KEGG: bcg:BCG9842_B2211 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="protein of unknown function DUF1910"
                     /protein_id="ZP_06250552.1"
                     /db_xref="GI:281419539"
                     /db_xref="InterPro:IPR015024"
                     /db_xref="InterPro:IPR015025"
                     /translation="MRDPLCNKEDLIETIEFNQQTICEMKEEIEELKADIENGIQRYP
                     RDNQSIIYITFADMFRYGMDMLLAKYSLGNHPDTMIDDYLDNITYLENCGEEEAGYIN
                     LLWMVGLGILLEMDKEVLKRLARVIERQRIEDALMDFLLKACDIGWNHSTTKYEKKNP
                     YEKTAEIIKIALHDKDKEAASKRLEKYMGKEWFKGHYDFGWRNAHKEPGYYGFWSFDT
                     AALAKILGLDDSALKDNNHYPYDLAHYKNGMTFDLSWYSVPKEEEDKEEETVVYGIPG
                     NPELERIIPGKFHSFVNEIINDYKTLPDEEFWKKYNLKEIWFDVEEYKEDNKDKNLLG
                     TIIVFMLVDKDYILQLDYKEELIDYIENIHNYWAKKEVKLISFELDNDQQYYAYVPKD
                     AEVGSLYEVKLTEVEKIEEV"
     misc_feature    complement(26572..26949)
                     /locus_tag="Cther_0131"
                     /note="Domain of unknown function (DUF1910); Region:
                     DUF1910; pfam08928"
                     /db_xref="CDD:149863"
     misc_feature    complement(26227..26568)
                     /locus_tag="Cther_0131"
                     /note="Domain of unknown function (DUF1911); Region:
                     DUF1911; pfam08929"
                     /db_xref="CDD:149864"
     gene            complement(26976..27404)
                     /locus_tag="Cther_0132"
     CDS             complement(26976..27404)
                     /locus_tag="Cther_0132"
                     /inference="similar to AA sequence:KEGG:BCG9842_B2210"
                     /note="KEGG: bcg:BCG9842_B2210 hypothetical cytosolic
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical cytosolic protein"
                     /protein_id="ZP_06250553.1"
                     /db_xref="GI:281419540"
                     /translation="MADDNLINNPKLKEAGYDLERIGGKVPTSPDDKITKGIDGIYIN
                     KNPNSNIKYVIDEAKFGKAGLSAKTRDGKQMSDSWLKGVRSGDNRILKAVNNDKQLAR
                     DIMRALRNNRIERVLSKVDANGKVTTYRLDSSGNIIGIWP"
ORIGIN      
        1 gcatacactt ctgttctgtt gatgttcaaa gttttctttc tcaatgcgga taattctgac
       61 ttgtaatcca ccacagattt cttgacttca tttatcaatc cgggcatttg gttgattttt
      121 ccggcatata acgttatagt tgccatttta tcacctcaaa attatcatcc caatgcttgc
      181 aatccgtggt tgccttataa taatgccagg aaacttttct gccttttcct ggcattatta
      241 tattatttct attctgaaaa agcaagtaga acgtacctat tttacaaatc aagccgccgc
      301 cagctcgttt tccttctctt cttttctcct ttttcttata ttataatcat agcaacaact
      361 attgacgtga ttaatactgc agacaccgct gcaataaccc acagccagaa aaatccaaca
      421 tgtatattcc ttatctcctg aaagctgaat tgttcaggca atatgtaaat actttatgac
      481 tgtacaaagc tcctttgcaa aaatcaagcg gctttgtgcg tatatcgtat atattaattc
      541 tttacaagct actaactctt tgaaaaccta aactatatat tttcttaatt tccgcttcat
      601 caagcggagg attgcacctt gcgttgtttt ctgcaagcaa tgccgcatag atgctctctt
      661 ctgtcattcc ttttgccctc atggttccgg caaggcttgt cagggtactg ttgcggtttc
      721 cttccttaat ctcggcaata atactgctac cttcaaaggg tgtaagcaat acttccaccc
      781 tttccatgag cttcaacaac catgctggag cttctgccgg gattctctca aagggagaat
      841 gtccttctaa ccattcatac cgattaccgc ttacatgaat gcttggagct acgacaatca
      901 gaccacctgt tgaacgcgta tcaagacccg atgcaaactt ggtcttattt ggaatactcc
      961 ggcctttagg gtatttaaag acatagtgcc gacctcctct tccagtaaca gcagtaaccg
     1021 tatccggaag ttttccatgt gttgcttcaa gtgcagatat ggtttcattg ccaccatgtc
     1081 cacatcaagc gccagccagc cggacttttc gcctgtagta atgcctatat tggcattggg
     1141 ggtttttctc caccatttgt ttatttgctt aacatcagta gtggaattct tgtaccagcc
     1201 ggtatatagc ggatgctttc ccttgctgtc gcattgttgt cccttcttgc aggagcagga
     1261 gccatcctca caaatccagt gcagaggtat aaccgggata ttggcttctg catattttaa
     1321 tgctgcgtcc atcattgtca ctttcaaatt ctcacctcct gtcgtgctgg aaataaattg
     1381 agcctgacaa atagttttta agactatctg ccaggctcta taggtgagtc attcgctccc
     1441 tttgcggctc tgtgccagat ttattcactt ttcaccccgc ctttttctcc agctttactt
     1501 caaaaacctt tctgcacacc gggcatttga tttcaacatc agcataatcg gcatcaaata
     1561 ctctgtgatt gcagtgagga cagcggacaa tgtacttctt cttactcatt cgccttcacc
     1621 tccggcttct ttagcttcat gagtcttgcc atcttcatca tcagaggctc taatatctct
     1681 ccaaccatgt aatgaaccat tggtgagtaa ttctcctttg tttcgtcaaa caacttggaa
     1741 agaaggtcgt agagattctt tatgtcctct tctgtggcat cagcagtgtt gatttcaatg
     1801 aaaatcttgg taccgtcacg cttggcgata tggtcgctca catacttctc cagagcgtat
     1861 cttgctatgc ttgatgtggt aacacttgcc tccggcattt gtgcttgaag ctcaccaata
     1921 atcgcatcca attcatccga ctgcctttgt gtaagcctta cccgtaacat actatccttt
     1981 tctgtagaca ttattgcacc tcctgtattt cttgttggtt ttatagtatc acattgtatt
     2041 acgatatgtc aagcgcagat aaaaagaaaa cccgacttgc cgttatattg gcttgccggg
     2101 tattgctttt tctacactat ttaatactgt aaaagataaa tctgaacaaa ttcataatca
     2161 ggttttcaaa tttttgctat tcattaatta ctacttcaaa tattatgtcg tcaaaatttt
     2221 catccggatg tgagtcatta catttatacc ttctggattt tccgttgatt tccagaatca
     2281 ttgctgctcc atttaaccat gcatcaactc gtcctccacc tgtatcccaa gcattccaaa
     2341 ccattaatgt tttacctgat attactttaa aaggaacatc tccatcaaca tcatctgccc
     2401 aaataatgaa atcattgcct tcacatgagt taatactcat taatccatca atttttatac
     2461 gtattccttg tttccattct gaattagttg aaataacttt caaccaacca gttatacccc
     2521 tttttacagg tatacgatca actcttataa gttctaaatt cttatattta actggattcc
     2581 ctttagcatt ttggaaatct gtatcaaaac ttggcataaa tctacctccc tgtttttcta
     2641 aatggatcaa tcaattgatg ttcatctggc caaactggtt ttaagttatc ataagtatta
     2701 atgcctggca agttagatct ctgcgggatt acatgatgta attccattga ttccattttc
     2761 ccagtcaatt cattatatct ttgtggtgct aatccttttt tcattcttgc aatattctcc
     2821 ggagaataat tttgagaatt ataatatgct tcatttttcc aatacctttg tcttacagta
     2881 ctccatgaag gctcttttcc tgctttcgtt aggttatcga tcgggtcacc gactttccat
     2941 ccttttgtag tactacgcgt tccctcacta caaggactat aactattata taattcctgc
     3001 taccatatct caatcaaaaa agaattatct tccattgctt tgcttccaga atatgaaatc
     3061 agttcttgtc gtcagccttc tcaaatggcc tgtattctat tctggttttc atcatgccgt
     3121 aaataatcct cacaagccgc cttgccacgc acacaagcgc ctgtggcttg ttcttgccct
     3181 ctttgacctt ctgctcaaaa tactccctga ataccgggtg tcttggcttt cctgacgccg
     3241 atactgctac catctggatt gcgagaaagt gaaatatcgc atttagtgcc ctgttgccat
     3301 tcctgcatct ttggtcttta ccctttccgg cagagctgaa ttgcaccggt gccaagccca
     3361 taaaccgagc cagcttgtct gagtcaggga aacggttaat atccccgatt tcagatataa
     3421 tctgcacttc tgtaacaagg tcgatacccg gcattgtatg tagcttataa cctgtcaaag
     3481 gtatcagctt tcttagttca tcgtcaattt cggctatcaa ctcctttttg ttcctgatat
     3541 cctttacaat gtttctgact ataaaatccc tttcgggctg atagtccttt cttgtgtctc
     3601 catccctttc aatcatggat ataatctcat gaatacgctg tattttaagc gcctgatgca
     3661 caggctttat cgtctgatat atttcttccg gtgttgtgtt ccatatatac tccggtgaag
     3721 ggtagttctc ccagaagcat aaggcactct tggaatcaac catggcaaag aatttcctgt
     3781 aggatgggta gctataagca agctggctgt ggagctggtt cttgttcatc acattgctct
     3841 ttacaatcaa atcccgtctt ttcaccattt gccgtattgt ccagaatata tcctcatgct
     3901 tggcatcctg caaagtgtcc accatatccc tgagcaccct tgccacacaa taggcatcat
     3961 aggagtcatc cttgtaaata atggggtttg caagccttac agcgcttgta taggcagggt
     4021 taacgtgctt tacttcaaac ttcctgccca ccagataggc agcaaggttt ctgccaaagc
     4081 ctctggtatc ttcaagtccg aatacaattt cctttatccc gcaaatcttc cttacatcct
     4141 caacgaatgc agggaatctg gatggcctgt tttcaaagtt aacctcaccc agtttattca
     4201 tccaacaatc aattacaact gcacaatgtg cgtccttgtg catatcaatt ccaacaaagc
     4261 aggtgtttcg tttatgataa atgtctatcc tctccttttt ccaatgtctc caccactcat
     4321 accggcaacc tcaatttaag agcgttagat tcgattaggg acatttcttg taaagaagtg
     4381 tcccttaacc ttaatcctcg caagggaacg ccaacctatc tattcctggt gtgacaaatt
     4441 acgtgatttc aggcatcacg agccttagtt caaatttctt aatgttcttt tactgcttcg
     4501 ctaggataca aatttcttaa catttctgac tgatataatt tctgtactaa taactgcagc
     4561 agcctttcaa attcctcttt acttgcccct tctgtttcaa caaagcttac ggctgcaacc
     4621 tacgctttta cgtttcaggg agcaatacag aggccttttc cccggccgct aaaccttctt
     4681 ccagcctttt gcttttagtc tttcctgtgt gtaatcttcc ggcctgcagt tctccaaggt
     4741 ttttctgcac ttgatgtttt cgtacagaat tgaatcccct ttgagaacca gcttctttat
     4801 ccagccgctg gacaacgatt tttcccatac ttcactttga atactggtaa aatacaactc
     4861 cagcgccctt tcaataatgg cattggcacc agacaagccc tcctgtttag caagtgcctt
     4921 agctttgttc aataaggctt cctctatggt tgtggtaatc tttgctctca cgctttcacc
     4981 ccttcctacg gttaaagcct ttattccgca gtaacattca tcactctgaa ccactgatat
     5041 agcaagtcaa ttatgcttta gaaagcagta tttctatcag ttttagaatt gagcaccgcc
     5101 cctgccaaag cctcttgtag gaggagcagc acttccaatt tgctcatttc accctaagta
     5161 ttgcttagcc tcagacttgg ctcaaatctg agcaaattat ctcgcttcca aagctactgc
     5221 ccatgagagc gttgctccgt ttttcggtgt tataggttta tcccaggtac cctgaccatc
     5281 tacacgcact atcaccctgt agtcggtcat atcctccatc cagccgggaa cattggagcg
     5341 atctagagca atctctttcc tcatgcctat ggcatactgg ctaaggtctg cgaggattaa
     5401 atctccctta gcacccaatg cggggcattt ctcagtgaat aagacctcct tacccagaag
     5461 cgtgaatttc ccgctctctt ccctgaacac cggtatctga gcgccaccgg taccaatggt
     5521 gatagtcatg gtaagcaatt gtggtattac cgatggattg gcaagccata ccgcattggt
     5581 aaaacaggac ggagcaagcc ttgaaaacat attgaccacg ttttgatagg taattgtggc
     5641 tgctgcttga gagtcctctt tatttacagt aatcagtgcc gggtcattta taataccaag
     5701 aggctgacct tcaccggttc cattgataaa ggcatagtcc atgtaccagc ccaagccttt
     5761 aatgagtgct ccagctaaca tttcttcaaa ggacatccca tctgcaataa gttcattgga
     5821 tgcctgtgag aaacaagcca gcttcttggc tttcagttga atcagcctta acttggctgt
     5881 ttttcgtgtg cctgtctgtc cttcttcaag ccattcgccc gagatgccgc cgaataggtt
     5941 gttggttctg tctgctccgt caaaggctgg tactttcttt gtttcacttc ccattgccca
     6001 taccgttgct cttggacgga tgatttcatt ctccagggat ttatccatca ggaaggctcc
     6061 gtattcctcc ggtacggaat atccgccgaa ttcgggtatt ccttccacca tactggcatt
     6121 tattagcctg ttgtcggctc tgcctgagtg aagtgttctc aggaattcat ccatggaatg
     6181 aaaaccattg ttgctgagtt ttactgtttc attgccatag aacatccctc tgaatgattt
     6241 tgatatagcc tttgtaaccg gagtttttgt ttcttccaca ggagatacag ctttttgtgg
     6301 catattcagt attggctcag aggttctgat atttaataat tcctcgtcaa tgctttcatt
     6361 aatgctcttt attttgtctg tgtagcgatt aaactgtcgc tcctgttcct ttgtcaaact
     6421 tccacccgct ttttccgctt cgtttaaaat agcttctgct ttctccacca attgcttttt
     6481 ctcatgtacc aaatctgcta taaatctcat gcttaaatcc ttcattttct taatattttt
     6541 ttgtaaatat ggtctggggt taataccccg tttgaatctg cattttttca tgcggcgctg
     6601 ccagcccgtt gtctttatgc tttgctgtag agatttgacc tccccctccc tctaaatcag
     6661 gatactgaga gtttactgac gaactgactc ttactgactc ttttttcaca aatttcacat
     6721 aagaaaaaat atatataaaa atttacggaa ttgacgtcag aagccgtcag tcgtcagtaa
     6781 tcacaaaagt atcccctcat ccgcaagacc aatgccatgc cagtccctgc tgccattggc
     6841 tccgctgcgt ttgacagcaa agccgcgctc cgtcattttt gcattaaata gcttttgtcc
     6901 aagtggataa tccccattct cccggcacca tgtttcataa gcatacctga tgcttctatt
     6961 ggaaactttc ctgccctcct ccacaatgca gcattcctct ataaaacttg agaaggtatc
     7021 catttcctcc cggtaacctt ctgtagcttc tttgacttca tcaggcattt caagtccttc
     7081 cttctgccaa agaaggcagc cctctactgc ccatgacaat atgccaggca gctcctctct
     7141 cagcttagcc ggtaactgct tatccttttt gtcctctgga atggtaacgg taaagggaat
     7201 cagcttaatg cgccgccata tgctgtgact ggtatctctt atgacaggtc tgtggtttac
     7261 tacgagaaat ggggtgaact gtggctggaa atcaaagtat tctccataaa ggaaccttgc
     7321 tgtgattctg tctccgcctg taaagctctt aatcaatgcc tcagagagcc tttgtccctc
     7381 atttatttct atggcagtaa cgagccttgc accctgaagc cttgcaatat catttcctat
     7441 cgcttctatc ctttttgcca taaaggtttc ggacggagta tttcttgcat aatctcccaa
     7501 cagttcggag atggtgttta gaaatgtgct ttttccgttt gctcctgttc cataaaggac
     7561 gaataaggct tgctctgaaa tatctccgct taaagatgag cctacagctt tttgaaggta
     7621 tcttacaagc tccttgcttc ctcccgtaat agtattcaga aaatccatcc atctgggagc
     7681 cttgctgctt ggtttatatt caacaggaca gattttgctc atatagtact cccgcttatg
     7741 aggaaggagc tcccctgtct ttaaatttac gacaccattc ttacagttca gcttccatat
     7801 atctgcatcc agctcatctg gcatgattac caagccttca aggtttgaag caacatcaat
     7861 catggcttta agcctgcctg cgttttcaga ctgcatggca tggcgcacta attctttcct
     7921 catggcttca tcttctatcc ggcttgcttc tgcgagcatg tctcttgctg tttttatagc
     7981 aaactgcata agttctccgg tttctttcct ccagcaacag ccgtcatata ccaaccagta
     8041 tttgaaagcc ggacaatacc ttatgattga accaaaccgg tcacgcagcc tttctgcatt
     8101 accgctgtct gtcctgtggt aatgcttctt catcggagga tttggctggt atcggctgac
     8161 actgtgcgct atctttttaa cttccgcttc atcaagcgga ggattgcacc ttgcgttgtt
     8221 ttcagcaagc aatgctgcat agatgctctc ttctgtcatt cctcttaccc tcatggttcc
     8281 tgcaaggctt gtcagggtac tgtttcggct gccttcctta atctcggctg caatactgct
     8341 accttcaaag ggtgtaagca atacttccac cctttccatg agctttaata accactccgg
     8401 agcttctgcc agggttctgt caaagggaga atgatccttt atccattcat accgattacc
     8461 gcttacatga atgcttggag ctacgacaat cagaccacct gttgaacggg tatcaagacc
     8521 cggtgcaaac tttgttttat taggaatgct cctgccttct gggtatttga agatatagtg
     8581 ccgacctcca cttcctgtaa cagcagtaac cgtatccgga agttttccat gtgttgcttc
     8641 aagtgcagat atggtttcat caccgccatc gtccacatca agcaccagcc agccggactt
     8701 ctcacctgta ggaattccga tattggcata aggggttttc gtccaccatt tccttatttg
     8761 ctcaacatca gcagtggaat tcttgtacca gccggtatat agcggatgct ttcccttgct
     8821 gtcgcaatta ctccctacct tgcaggagca tgagccatcc tcacaaatcc aatgcagagg
     8881 tataaccggg atattggctt ctgcatattt taatgctgcg tccatcattg tcactttcaa
     8941 attctcacct cctccgagaa aataaataga gcccgacaaa tagtttttta gactatctgc
     9001 caggctctat aggtgagtca ttcgctccct ttgtggctct gtgccagatt tattcacttt
     9061 ttaccccgcc tttttctcca gcttcacttc aaaaaccttt ttgcataccg ggcatttgat
     9121 ttcagcatca gcataatcgg catcaaatac tctgtgattg caatgaggac agcggacaat
     9181 gtactttttc ttactcacct gccttcatct ccggcttctt tagcttcatg agtcttgcca
     9241 tcttcatcat cactggctct aatatctctc caaccatgta atgaaccgtt ggtgagtaat
     9301 tctcctttgt ttcgtcaaac agcttcgaga gaaggtcgta gagattcttt atgtcctctt
     9361 ctgtggcatc tgcggtactg atttcaataa aaatcttggt tccgtcacgc ttagcaatat
     9421 ggccgctcac atacttctcc agagcatatc ttgctatgct tgatgtggta acgcttgctt
     9481 ccggcatttg tgcttgtaac tcatcaatga tagcatccaa ttctttgtgt aagccttacc
     9541 cgtagcatac tatccttttc tgtagacatt attgcacccc ctgtatttct tgctggtttt
     9601 attgtatcac gatgtattac actttgtcaa gcatggataa gaaaaaaggc cacgccagcc
     9661 gaaactgtgt gacccatatt tatttttact atgtttctga ataaattact ttagaagtca
     9721 atatgttaat tctatcacct gagtttaata atatactcag acaaaagctc tcattattgc
     9781 tttgatattc aacaagtcta ttaataatat cagctccatc attaatacta acttcatcta
     9841 catatatacc tgctccccaa ggctcataaa agctaatatc tgcatactgg acatcttcac
     9901 aggtaattgt cacctcttta acgctgttat tacatttata taactttaaa ggtatttcta
     9961 ttctgtgcat gttataatca caaataactt tagcaacttc agcatcatgt aagttaaaat
    10021 cttgtatttt atggattgta aatttatcaa aaatcaatat tttcacctct tcttacttat
    10081 ttattttagg aacactttcc cctggtctta tatgtgtgtc tcctgtatca ggatgcggta
    10141 ttctattctt tccgtcagga gttacatgat aatgattacc atacttaggg tctgcattcc
    10201 attcatatac agctttccct gttttggggt catgccattt aattatttta ccattattat
    10261 actccttacg aaccaaacca tctggattaa acgttttggg gtcttcagga aaaacagtgc
    10321 tactcgttcc cttaacatac ttattcgcat tatgaaccaa taccctattt tcgccaacat
    10381 gatacgtatg aaaattatcg accttaaaat tgtaaacctt tacaggctta tctgttattt
    10441 caagcttttt ctcttccacc accaaaacat tgcctcttga atcaaccaac ttatctccta
    10501 cttgcagttt tcccgcttca acaaaaccca catctttaac ataaaacgga tgctcaaagg
    10561 ttgtcttgat tacctctcca ttgattgtca aatgcaaaag ctccgttgtt tctctcacat
    10621 atgtctcaag caccgtcttc tcggctactt caaaagtctc cggattcgtc gcaattacct
    10681 tgtcccctgc cttgatattc tctatcgcaa ccaagcctgc cacagtcaat atcattgtac
    10741 ctgcaacaaa gcacttcatt gtcgatgccg ccccggcact gaaaacagcc agcgcgttta
    10801 cagcaatctg gaatccgtta taaagtgcat tggaatgcag cttccggtta aattcaacca
    10861 atgcattgga tggttcaaac aacgatattc ccattgccag catgtcaaat ccatccatac
    10921 taaaagaaag tgctgtggtc atataacata aaacattcca ctacctttgt acaacttgta
    10981 atgtgtttcc tgtctctgaa tataattgaa ttaatatata aatataatat atattaaaca
    11041 aaaaggtcac attagttgaa attacgtgac ctgcaaattc tccctatccc ttaagcttaa
    11101 gttttttatg attcgttagt agctttgtac aaataaaaaa ttgccatata aaaagctaat
    11161 ttgtgttatc ttcttttaag tactttttat cgttttcttt aaatatcttt atcatatcac
    11221 aacaaaagtc tagccatctc tcagcaacac ttctgtcaat tgaaacaata tcaattggtt
    11281 tgtaattatt tagaaaattg tcaaaagttt catattcact ttcattctca ggataatcgc
    11341 agttccactt gtaaattgga cttatttcaa tatatatttt atcatcaata ttatacataa
    11401 aagtttcaat acctatatga gttggagttg accaaaggct aaaattttgt gatggatcaa
    11461 caagactttg aataacattt tcgtcatcag ttgtccacaa ttcatttgca taaatattat
    11521 agtaatatcc aattccctta tctatatatt ttctctgtat ttgtaagtca aaatttaatg
    11581 ctttctttag taaattcttt aatatttgta ttgcctccgt tgcaaaatca tcaacatata
    11641 aatcatattc tatttggtct ttcagatact ttatagatat aatatcaaat ggctttatat
    11701 ttttcttttc acatggtaag tatattttaa taaattttgt tcttgtaatt tctaatttaa
    11761 ttaaatcaat catttcttca atcatccttt actttttatt tgcacgaatt tcgtaaattt
    11821 cataaactac tgctgaatta ctctattatt gttgtaattc ggaaaacgtt ttgtttttaa
    11881 tttgattttg atatttcatt tatcatatca attattttac ttgtcaactt aggtttttta
    11941 gctacctcct taacatatcc tgcctttttg agagcatttt tcatcctgtc agtcaaaggc
    12001 ggaagatctg gagtaccttt actccaaggt ctaacatgtc catgaaactt ttcaccacct
    12061 gtatgatcta acacaacaaa atctccattt atgtcaattc caactcttct ttttgatgta
    12121 tctcttatat caacagagtt gtctaaagca aactgaccgt cttgcggttt tttacttttt
    12181 atactatcat caacttttcc gtgataatca gcatcttcat atattccatt tttatatgtg
    12241 tatttaccat ctggtgaatt atactttacg ttatgaacca gcacttcatt attgccaaca
    12301 tgataagtat gaaaatcagc tacttgaaag ttgtaaactt taatcggttt atcagttatt
    12361 tttatttttt tctcttccac caccaaaaca ttgccttttg aatctagcag cttatctcct
    12421 acttgcagtt ttcccgcttc aacaaaaccc acatctttaa cataaaacgg atgctcaaag
    12481 gttgtcttga ttacctctcc attgattgcc aaatgcaaaa gctccgtcgt atctctcaca
    12541 tatgtctcaa gcactgtctt ttccgctact tcaaaagtct ccggattcgt cgcaattacc
    12601 ttgtcccctg ccttgatatt ctctatcgca accaagcctg ccacagtcaa tatcattgta
    12661 cctgcaacaa agcacttcat tgtagatgcc gccccggcac tgaaaacagc cagcgcgttt
    12721 acagcaatct ggaatccgtt gtgaagtgca ctggaatgca gctttcggtt aaattcaacc
    12781 aatgcattgg atggatcaaa caacgatatt cccattgcca gcatgtcaaa tccgtccata
    12841 ccaaacgaga gtgctgccgt aacctttgat gtaacattta tcgcttttcc cactgtgctc
    12901 atacattgga tgcttttccc tgcagctgct cccaaagcac caagcccggc acatgccgct
    12961 cctgtcaccg ctccggaaat cgctccgctc aatgctccgt ccgcaaatcc ttccagaaac
    13021 gaacctccat ttatcgccgc ggctattcct ccaaccgctc cccctatcaa tcctccggcc
    13081 aatgctcccc agaatgctcc tgccagtatg actcccaata taccgcctgt caatgccgcc
    13141 gctatcccca acccggtaat aactactgcg gcagccacta tcttggcaat ggatttccaa
    13201 ttctctttac accactccgc aaccgccttt aagccgtccc tgattttttc ccagccgctt
    13261 ttctcgcttt ccggttttaa ataataatat tctttgtaaa aattttcttt ccgtttattg
    13321 ataagctcag ccacttcttc atcgatacgt actacttccg atataaactt ctcgctttcg
    13381 ctgcagaatt tctcaagtga atcaattttt ctatcctgag tctgggaaga tgcctgtatg
    13441 gaacttatta cttcatccaa attgcataca cttctgttct gttgatgttc aaagttttct
    13501 ttctcaatgc ggataattct gacttgtaat ccaccacaga tttcttgact tcatttatca
    13561 atccgggcat ttggttgatt ttcccggcat ataacgttat agttgccatt ttattaactc
    13621 aaaattatca tcccaatgct tgcaatccgt ggttgcatta taataatgcc aggaaacttt
    13681 tctgcctttt cctggcatta ttatattatt tctattctga aaaagcaagt agaacgtacc
    13741 tattttacaa atcaagcggc cgccagctcg ttttccttct cttcttttct cctttttctt
    13801 atattataat catagcaaca actattgacg tgattaatac tgcagacacc gctgcaataa
    13861 cccacagcca gaaaaatcca acatgtatat tccttatctc ctgaaagctg aattgttcag
    13921 gcaatacgta aatactttat gactgtacaa agctcctttg caaaaatcaa gcggctttgt
    13981 gcgtatatcg tatatattaa ttctttacaa gctactaact ctttgaaaac ctaaactata
    14041 tattttctta atttccgctt catcaagcgg aggattgcac cttgcgttgt tttctgcaag
    14101 taatgccgta tagatgcctt cctccgtcat tcctcttgct ctcatactcc cggcaaggct
    14161 cgtcagggtg ctattgcggc tgccttcctt aatctctgct ataatactgc taccttcaaa
    14221 gggtgtaagc aatacttcct ccttttccat aagctttaat aaccatgctg gagcttctgc
    14281 cggggttctg tcaaagggag aatgatcctt tatccattca taccgattac cgcttacatg
    14341 aatgcttgga gctacggcaa tcaatccacc tgttgaacgc gtatcaagac ccggtgcaaa
    14401 cttggtctta ttaggaatac tccggccttt agggtatata aatacatagt gccgacctcc
    14461 acttcctgta acagcagtaa ccgtatccgg aagttttcca tgtgttgctt caagtgcaga
    14521 tagggtttca tcaccaccat cgtccacatc aagcaccagc cagccggact tctctcctgt
    14581 aggaatgcca atattggcat taggtgtttt cgtccaccat ttctttattt gctcaacatc
    14641 agtagtggaa ttcttgtacc agccggtata tagcggatgc tttcccttgc tgtcgcaatc
    14701 gctccctgcc ttgcaggagc aggagccatc ctcacaaatc cagtgcagag gtataaccgg
    14761 gatattggct tctgcgtatt ttattgctgc gtccatcatt gtcattttca aacttctcac
    14821 ctcctgtcgt gctgaaaata aacagagcct gacaaatagt ttttagacta tctgccaggc
    14881 tctataggtg agtcattcgc tccctttttg gctctgtgcc agatttattc actttttacc
    14941 ccgccttttt ctccagcttc acttcaaaaa cctttctgca caccgggcat ttgatttcaa
    15001 catcagcata atcggcattc aaatactctg tgattacagt gagggcagcg gacaatgtac
    15061 tttttcttac tcacctgcct tcacctccgg cttttttagc ttcatgagtc ttgccatctt
    15121 catcatcaca ggctctaata tctctccaac catgtaatga accattggtg agtaattctc
    15181 ctttgtttcg tcaaacagcc tggaaagaag gtcgtagaga ttctttatgt cctcatctgt
    15241 ggcatctccg gtagaaactt caataaaaat cttggtacca tcacgcttgg cgatatggtc
    15301 gctcacatac ttctccagag cgtatcttgc tatgcttgat gtggtaacac ttgcttccgg
    15361 catttgtgct tgaagctcac caacaatagc gtccaattca tccgactgcc tttgtgtaag
    15421 ccttacccgt aacatactat ccttttctgt agacatcatt gcgcctcctg tatttctcat
    15481 tggttttatt gtatcacttt gtattacttg ttgtcaagta tagataaaaa gaaacccagc
    15541 ttaccgtttt agtggtttgc taggtattaa gtattaattg tgctttacga ttcaggtaag
    15601 tgaagctact tcatgttaaa tctgtctaaa cataaacaat gatcaacctt ttaacaataa
    15661 tattttatta aatcagctct aagtttctca acaaaatcct tctcatccac atctattgaa
    15721 aacaggtcac catcttcaaa tagattattt ttagcctctt catagttact agcagattca
    15781 ataacataag ctctaaaagc ctctataaaa gtaaatctat aatagcttcc tttgttttta
    15841 ttatgataca atttattacc gttaatctcc acaacctcga atcctagatc atgtaaaaca
    15901 ttatcaattt gtttcaaaat atcattcata accccacctt ctttacttaa gtatgttgcc
    15961 attcatatca taacgtattg tccctgttga acctgatgat aatttccaat atgcatttcc
    16021 accatggtga cctgaacctg ctggatgata ctgcaggagt ttgtctccac cccaattgac
    16081 cttaaatcct ccaccatctt caaaaagtat tccttttaaa gagccatcac ttagcggctg
    16141 agggttatat ccgttgtttt ttaaataatt atataactcg tcaggagtta aattctttag
    16201 tttactcggg tcattaataa aatcatctaa gctatcaagg ttttttagag tactactcgt
    16261 tccctcacta cagggattat atatagtata taatccctgt taccatttat caatttaaat
    16321 ttacaaatat tcctaattat ttccttcttc ttctttcttc tcatacggtc tatactctgt
    16381 ctttgtcttc atcataccgt agattaatct tacaagcgtt cttgatatac atataagagc
    16441 ctgtggcttg tttttaccct ctttgacctt ctgttcaaaa tactctctga atactggatg
    16501 ccttggcttt cctgaaggtg atacagctac catttgtata gccaaaaaat gaaatatagc
    16561 atttaactct ctgtttccat ttctacacct ttcttcctta cctttacctg ctgaactaaa
    16621 atgtacaggc gctaacccca taaaacgagc taacttatct gaatttggaa atctgttaat
    16681 atcaccaatt tcagacacaa tctttgcttc tgtgataagg tctatccctg gcatagtttg
    16741 cagcttatac cctgtctgtg gcaataattt tcttaactgc ttttctatgt cttttaatag
    16801 ctcttgattg ttcttaatat cttttacgat gtttcttact attgtatctc tttcttcctg
    16861 ataccccttc tgtgtatttc catccttttt aatcatatca ataattgcat gaacacgctc
    16921 tatcttgaat gcctgatgta ctgcttttat tgtttcataa atttgttctg gtgtagtaca
    16981 ccaaatatgc tctggtgaag gatagttctc ccagaaacac aatgcacttt ttccatcaat
    17041 ttgtgaaaag aacttcttat aggatgggta accataagac aactgactat gtaattgatt
    17101 tttgttcata acattatatt tgactattat ttctcttctt tttaccaact gtctgattgc
    17161 ccaatatata tcctcatgtt ttgcatcctg taatgtatcc accatatccc ttaataccct
    17221 tgcaacacaa taggcatcat aagaatcatc cttgtatata ataggatttg aaagtcttat
    17281 tgcactggta tatactggat tcacatgttt gacttcaaac tttcttcctg taagatatga
    17341 agccagatta cggccaaaac ctctggtatc ctcaagccca aatacaaagt cctttgtacc
    17401 gcatattttc ctaatctcct caacaaatgc tggaaacttg gatggtttgt tttcaaagtt
    17461 gacttctccg attttttcca tccagcaatc aatcacaact gcacaatgct tttccttgtg
    17521 catatctacc cctacaaagc atatatttct tttattataa atatgtatcc tctccttttc
    17581 ttatctccac taagcacatc ggcaacctca atttaagaac gttagctttt tacagcccgc
    17641 aagggaacga cagcctatct gttcttcgtg tgacaaatta cgtgattaaa gcatcacgag
    17701 cctttattga ctacactttt ttgatgatga taccgtcacc attcactaaa gtccagtctt
    17761 tttaattttt tacttgctta tataccttaa tctgtcacta tttttgttca cataaaaacc
    17821 ataactgtta gtgattatct gatttatgcc ctactcttaa tttataactg cccttttttc
    17881 cttgtcgctc aatgcttttc tgacttatat aaatttgagg ttaatgctta aaaaaatttt
    17941 taactacaaa aagagaccga acataatcgt ccaatctctt cccgttaatc catctttata
    18001 tgtttatact attcataaat acgaaacaac tgcccctgct cctttaatgc tctgtaaagg
    18061 gtgctactgc ttaccccaga taactttgca atttcctctg tggtaaataa cttgcttgca
    18121 tacagcttta atgctgtttc tatctgttcc tgaggtatct ttggtcttcc tactacccct
    18181 tgctttcttg cctcttcaaa ggctaatctt cttttcttct cagcataata tttactgatt
    18241 tctattgaac cttgaagtct gtcgaaatac tctaaaccat ttagaaatgg ctccattata
    18301 ctatgtatca agataccaaa gtcttgcagt tcctttagta gatgtaatag ttcacttcgc
    18361 ttttctgcta aatctgttac tgttcttaat actattgcat cccctggctc aatattctct
    18421 aaaagcgcat ctaattcatc tttattatct gctgtatcaa tgtatatgtt atcttctgat
    18481 atattctgtt cttttatata tctaaacaag caactgttat ctttgaactc accgcctgta
    18541 ttttcaataa aatatgcgta taccattatt cctctccccc ctttgtcaaa acctcttaca
    18601 atttaggaat atatataccc tttgagatta aatcaatttc ttataattct tatctactta
    18661 ttgccaaaat tactccttat tcttttttct tcataaacta tctctatatc aaccgttttg
    18721 agtaatagat aaacttgaag tattttggga atgaacttgt tttataccca aaacatatat
    18781 ttatgtattc cttaaaccac ctgagatatt ttctttccca aaacctcaac tatcacctgt
    18841 aacaaacaac ctttaagtaa taccaatcct gcatatctct cttgaaattc acgtattcac
    18901 tttcattttc tgcaatctgc ttaccactgt atatgataag atagcttata tccttttgct
    18961 ctgtgagctg ttttactctt tttgtaatat cttttatacc cccaaaagtt ataatgatac
    19021 tgtctacttg gatattctcc tgacaacatg ctgttgttaa ttgcgctacc tgtgctgcca
    19081 ttacttcaag gtctgctttt gccgtactcg ctggtcttac tgctattatt gctttaggca
    19141 acaactgcac aggtggtctt actgttctta tatctttact cattattact cccctctctt
    19201 ttaactgcat ctgctacatt agtaaatgcg ctcacatcta ataaaatcat atcatctgtt
    19261 acaaatttaa attccattat caaatagcag tatttattaa gtatcctcag aatatcaata
    19321 tctgccttat ctaatgtgag cggtaaagtc atctttcctg tcatttgatt tacccccttc
    19381 ttttttactt ggatacttat attacttttt tctgttagtt gatgaacttt tcatgttcaa
    19441 aattttttta tttgtccaat taagatttat ttttctacac atcagacaaa acatcataaa
    19501 aaaagatagt gccttataca ctacccttgt ttaccactta cttataccgc tatattagaa
    19561 tacttgatgc tatcaaccat ctttatcttt actttatgtt ttctttactc ttattttctt
    19621 tactcttatt ttctttttct tgttcttgtc tttattcaac tacttttaac ttttttccac
    19681 caccaacaac cttccctaat agattcacat atatgcatcc atttatgcat atatgtgaat
    19741 cttaactgta gaatttggtt tttaactccc atttttacat tgatattact ggatttaaaa
    19801 attataaaaa aattttttta agttttttta ttaaaaatct cttatcagta cattatcaaa
    19861 taagcgggtg atataaaata gtgcactctt ttttatttat aaaacccttg cacctactta
    19921 atatcccaat ttcctgatgc ataaattata ataaaaatag cagatatact aaaatactgg
    19981 acaacgtgta taataagttg aacatgtttt ataaattcaa aatgcacgac ataacaatat
    20041 aaaatttatc tgttttcatt aactatccat attgcatata taggaaaagg tcacatcagc
    20101 ataagctgtg tgaccctttg gatttaaagt caaatctcat cattaaatgg tttacgtaca
    20161 ttttccaaat acttttctga aattgctcct atttttttat agttttctct tgctttattc
    20221 aaactaattc catttgctcc tccttcataa tctgggtctt catattgaac accatcatct
    20281 tcccagaaac atactggaca aatttcaaat gttcctggcg gttcactttc cattgtatag
    20341 taaccacaac atacacattt gtactttttc aatttaaact ccctccttat tgtctattaa
    20401 aataattaat accatcagta ggtttaaaat atgttcttat tattccatca gaggttttaa
    20461 cagcaaattc atttgaaatt ttgttataga agatagtatc accgtttggt ctaactttag
    20521 ttaaaatatt gcctccaggc ttagaactca ctaaatcctg agcacctttc aaatattgtt
    20581 ccttcgttat atttccaaac tcagcagcat gctttttaaa gtgactatct aataattcct
    20641 gtgttttaaa tccagcctta ctcgttccct taacatactt attcgcatta tgaaccaata
    20701 ccctattttc gccaacatga tacgtatgaa aattatcgac cttaaaattg taaaccttta
    20761 caggcttatc tgttatttca agctttttct cttccaccac caaaacattg cctcttgaat
    20821 caaccaactt atctcctact tgcagttttc ccgcttcaac aaaacccaca tctttaacat
    20881 aaaacggatg ctcaaaggtt gtcttgatta cctctccatt gattgtcaaa tgcaaaagct
    20941 ccgttgtttc tctcacatat gtctcaagca ccgtcttttc cgctacttca aaagtctccg
    21001 gattcgtcgc aattaccttg tcccctgcct tgatattctc tatcgcaacc aagcctgcca
    21061 cagtcaatat cattgtacct gcaacaaagc acttcattgt cgatgccgcc ccggcactga
    21121 aaacagccag cgcgtttaca gcaatctgga atccgttata aagtgcattg gaatgcagct
    21181 tccggttaaa ttcaaccaat gcattggatg gatcaaacaa tgatattccc attgccagca
    21241 tgtcaaatcc atccatacca aaagaaagtg ctgccgtaac ctttgacgta acatttatcg
    21301 cttttcccac tgtgctcata cattggatgc ttttccctgc tagagctcct aaagcaccaa
    21361 gcccggcaca tgccgctcct gtcaccgctc cggaaatcgc tccgctcaat gctccgtccg
    21421 caaatccttc cagaaacgaa cctccattta tcgccgcggc tattcctcca accgctcccc
    21481 ctatcaatcc tccggccaat gctccccaga atgctcctgc cagtatgact cccaatatac
    21541 cgcctgtcaa tgccgccgct atccccaacc cggtaataac tactgcggca gccactatct
    21601 tggcaatgga tttccaattc tctttacacc actccgcaac cgcctttaag ccgtccttga
    21661 ttttttccca gccgcttttc tcgctttccg gttttaaata ataatattct ttgtaaaaat
    21721 tttctttccg tttattgata agctcagcaa cttcttcatc gatacgtatt acttccgata
    21781 taaacttctc gctttcactg cagaatttct caagtgaatc aatttttcta tcctgagtct
    21841 gggaagatgc ctgtatggaa cttattactt catccaaatt gcatacactt ctgttgatgt
    21901 tcaaagtttt ctttctcaat gcggataatt ctgacttgta atccaccaca gatttcttga
    21961 cttcatttat caatccgggc atttggttga ttttcccggc atataacgtt atagttgcca
    22021 ttttattaac tcaaaattat catcccaatg cttgcaatcc gtggttgcct tataataatg
    22081 ccaggaaact tttctgcctt ttcctggcat tattatatta tttctattct gaaaaagcaa
    22141 gtagaacgta cctattttac aaatcaagcg gccgccagct cgttttcctt ctcttctttt
    22201 ctcctttttc ttatattatg aatcacagca gcaactattg ccgcaattaa tactgcagac
    22261 accgctgcaa taacccacag ccagaaaaat ccaacatgta tattccttat ctcctgaata
    22321 ttgtttacat ttcccgccat atccacaagg acaattccaa cgttgtgcca accctttccg
    22381 agggtaaaag ttaatgtatt gttatcactg taatatttga aatctatttc cctgccgcta
    22441 tcatatacct tgcaccggtt ttcgtcaacc aattcgttga taattgagcg aaaaagggca
    22501 aaacactcca ttataaataa ttatagacga attaaatcaa atttatgtgt aaaacttagc
    22561 aaaaccggca ataatatata atattgaagt gatttaggat ttacattctg taaactttga
    22621 aaacttaaaa tttcttgcca ggaagaactg aaaaattttt aatacatgaa attatttata
    22681 ctcccattgg attcaataaa gaacattacc cttaagtatt tgcctcctta tagctccgag
    22741 ttgaattcaa tcgatcacct tttgaaagac atccgaatga atgtaacgca taacaacttg
    22801 tttgaatcta tagctgaaat tgtgcaggca atatctaaat actttatgat tatacaaaga
    22861 tcttttgcaa aaattaagcg actttgtaca tatatattat attataattc tttacaagct
    22921 aagagactgt aaaatattta tgtaaactaa ttgactcctt ctatgataga atactaaagt
    22981 ataggaggag ttttttatgg caagaaaaag aataataaca ccagaaaaga aagagcttat
    23041 cagaaatctc atttctgagt acaacatcac ttgagcaaag aatttgcagg aagcattgaa
    23101 ggatctgctc ggagatacga tacaaaatat gttggaagca gagctggatg aacatctcgg
    23161 atatgaaaag tacgaatcaa ctgaagaagc gaaatcaaat taccgtaacg ggtacacatc
    23221 aaaaacatta aagtcaagtg tagggcaagt agaaatagat atcccgcggg accggaatgc
    23281 agaattcgag ccgaaaattg ttcccaagta taaaagggac atttcagaaa ttgaaaataa
    23341 aataatagca atgtatgcgc gtgggatgtc taccagagaa atcaacgagc agatacagga
    23401 aatctatggg ttcgaagtat ctgctgaaat ggtaagtaag atcactgata aaatactacc
    23461 tcagatagaa gagtggcaga aaaggcctct gggagaggtt tatccgatag tatttattga
    23521 cgcaattcat ttttcagtaa aaaatgacgg cattgtttcg aagaaggccg tatatattgt
    23581 gctggcaatt gatatagaag ggcagaaaga tgttatcggc atttatgtag gagaaaaatg
    23641 agagctcaaa attctggctg agtgtcttaa aagaccttaa aaacagagga gttaaagaca
    23701 tcctgattct ctgtgctgat gcactttcag ggataaagga tgcaatcaat gcggcttttc
    23761 cgaatactga atatcagagg tgtatagtac accagataag aaacacgcta aagtatgtgt
    23821 cagataaaga ccgaaaggaa tttgccaggg acttgaaacg gatatatacg gctccgaatg
    23881 agaaggcagg gtacgaccag atgcttgagg tttcagagaa atgggagaag aaatacccgg
    23941 cagctatgaa gagctggaag agcaattggg atgttatttg tccatttttt aagtattcgg
    24001 aggaactacg taaaatcatg tatacgacca atactattga gagcctgaat agcagttata
    24061 gaaggataaa caaatcaagg acagtatttc ctggcgacca gtcactttta aagagcatat
    24121 atttagctac agtaaagatt acttcaaaat ggacgatgcg ttacaaaaac tggggtttga
    24181 tactgggaca gctacagatt atgttcgaag ggcgtatata gtataatcaa ggggttcagg
    24241 gaaactctgg tttcctgaac ccctctgtaa tattttatac gcatcatctt tgtcaaattt
    24301 ttcttttgta agaatttctt atcagaaatt cttttgaatc tataaaattt gacaaagcag
    24361 actttcgagt cttaaaatat atttaaacac taacatagaa ggaaaattag tttacacaaa
    24421 aatatttaca ctgccaatat ttttataaaa gccatattct tatccaaaac tctaaatact
    24481 gcagattatc cccttacaca taatactgaa tatacctctc ttccaatggc aactcctcat
    24541 catcaactat cttttcctcc aataacttct ctttatcctc caacttcgct ataaacaact
    24601 cataaaaatc acttcctgtt ggaaagcaaa acagtccata ccctgctttc tccaatatct
    24661 tgttcacttc ttttatctta tctgtcaaat catcatactc catctcgtcc agctcttcca
    24721 actcctcctg tgttgcaagc tctattccat gactgaattc ataatccatt atataattta
    24781 ttatctcgct cccctcttct ccaccataat caacacacag aaacttccct tccgatatcc
    24841 cgtattccaa tatcgcctca ctcaaatcat ttccttccaa atcatttcct tccgaatcac
    24901 ttaaaattgg tttcacttcc tcaatgtctt caaatataat cccaactata tcttccattg
    24961 ccataacagt ttcctcctat tcaaacagtt ttccatgctt gttgggaatg taatttggat
    25021 aattctttcg gtaaaactca tctatggctc tcaacaaagg atcccactcc ggatatggct
    25081 ccggctcatt aatcaccacc ttcgcttccg gtgtgttcat cagcaagtct tcaaatttat
    25141 ccggtaccgg caaacctaat ttcctcctta tatgcattaa aaacaatatc tcatatggat
    25201 aaaatccata cgtgtaatca ccaaattccg gttcgttatc aatgtccgaa actaatacgg
    25261 aatgatacaa tatcatttta tcaatcacgc ttttaacctc ttccaaattt ggactcaacc
    25321 ataaatccaa tgcttcttta taaacatcaa gatcttcagg aattaattca aatgaacgcc
    25381 cctctttttt tcagcttatc tttcactgcc aaatgtacat tttgactctc ccctgctatg
    25441 gttctgttcc tatacctttt aacattgatt atattaacat tgattatatt aacattgaca
    25501 accataaaca atcctaataa aacttcttat tattctcaat acaatattat cttccccaaa
    25561 aaaaataaca caaaaaatac tccttcccaa atactgtcct atagtttttg tttcgccagg
    25621 aaggagattc ccaaaatcaa actatatata tccaattata cagcagattc ttcataaaca
    25681 actcatcttc ttcacactat tacacaataa acactaaacc tcctctattt tctccacttc
    25741 tgtcagtttt acctcataca acgaaccaac ctccgcatcc ttcggcacat atgcatagta
    25801 ctgctggtca ttgtctaatt caaagcttat aagcttaact tctttcttgg cccagtaatt
    25861 atgtatattc tctatatagt ctattaactc ttctttataa tccaactgca aaatataatc
    25921 tttgtccaca agcatgaata ctataatcgt tcctagcaaa ttcttatctt tattatcctc
    25981 cttatactcc tccacatcaa accagatttc tttcaaattg tatttcttcc aaaattcttc
    26041 gtccggcagt gttttataat catttattat ctcatttaca aaactgtgaa acttcccagg
    26101 tattatcctc tccaactcag gattacccgg tataccatat accaccgttt cttcttcctt
    26161 atcttcctct tcctttggta cactatacca actcaaatca aaggtcattc catttttata
    26221 gtgtgccaaa tcataaggat aatggttgtt gtcttttaac gcactgtcgt ccagccccag
    26281 tatcttggcc agtgccgctg tatcaaaact ccaaaaacca taatagccag gttccttatg
    26341 ggcattcctc cacccaaagt cgtaatgtcc cttgaaccat tcttttccca tgtatttttc
    26401 aagccttttt gatgccgctt ccttgtcttt gtcgtgtaat gctattttta taatctctgc
    26461 tgtcttttca tacgggttct ttttttcata tttcgttgta ctgtggttcc aacctatatc
    26521 acaagctttc aatagaaaat ccataagtgc gtcttctatt ctttgccttt ctataactct
    26581 tgccagtctt tttaacactt ctttatccat ttccaaaagg atacccagtc caaccatcca
    26641 taaaaggtta atgtagccgg cctcttcctc accgcaattc tctaaatatg ttatgttgtc
    26701 taaatagtca tctatcattg tatcggggtg attgcccaag gaatattttg ctaaaagcat
    26761 gtccatacca tacctaaaca tgtcagcaaa cgtaatataa attatactct gattatctct
    26821 tggatatctt tgtataccat tttcgatatc agcttttagt tcctctattt cttctttcat
    26881 ctcgcaaata gtctgttggt taaattctat cgtctctatc aagtcttctt tattacataa
    26941 cggatctctc attatcgtaa cctccttcga attacttatg gccaaattcc aattatatta
    27001 ccactgctat ccagtctata tgttgttact tttccatttg catctacttt ggataatact
    27061 ctttctattc tgttatttct taatgccctc attatgtcac gtgctaattg tttatcatta
    27121 ttcactgctt ttaaaattct attatcccct gatctaacac cctttagcca agaatctgac
    27181 atttgttttc catctcttgt ctttgcactc agtcctgctt ttccaaattt ggcttcatca
    27241 atcacatatt taatatttga attaggattc ttgtttatat atataccgtc tatccctttt
    27301 gtaattttat catccggtga ggtcggaacc ttacctccta tccgctccaa atcataccct
    27361 gcttctttca attttggatt attaataaga ttatcatctg ccag
//
