LOCUS NZ_ACVX01000002 157709 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00038, whole genome shotgun sequence. ACCESSION NZ_ACVX01000002 NZ_ACVX00000000 VERSION NZ_ACVX01000002.1 GI:256003301 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 157709) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 157709) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000002. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..157709 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene <1..261 /locus_tag="ClothDRAFT_0260" CDS <1..261 /locus_tag="ClothDRAFT_0260" /inference="similar to AA sequence:KEGG:LPC_2299" /note="KEGG: lpc:LPC_2299 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428293.1" /db_xref="GI:256003302" /translation="NNYPVVDMEFAEFMVERKIKILGMDTPSPDKPPFPVHRLLLKNE IFILENLANLEALLDVEKFEVIALPLNIKADSSILRVVAKVV" misc_feature <4..258 /locus_tag="ClothDRAFT_0260" /note="Putative cyclase; Region: Cyclase; cl00814" /db_xref="CDD:154016" gene complement(330..938) /locus_tag="ClothDRAFT_0261" CDS complement(330..938) /locus_tag="ClothDRAFT_0261" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428294.1" /db_xref="GI:256003303" /translation="MRRNLTIVFTILLCVIISISCVAFGNSQDNDKQEEKDVLLSHVE YEKEYGKSDIIALVDEGPLTDEYYFDEGSLIVKGKLKGIKGVAFTVGEVPCMVYELEV TDTIVNGTGKKHKTVNLAVSEMIIDYVEDKLQMNQESVFYLTLNDGAFPHLKEDYYGL VSYTGGIVPFNGDKESYNRLKKNLRERKKDFDNKNRKIEKNQ" sig_peptide complement(861..938) /locus_tag="ClothDRAFT_0261" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.879 at residue 26" gene complement(1179..1553) /locus_tag="ClothDRAFT_0262" CDS complement(1179..1553) /locus_tag="ClothDRAFT_0262" /EC_number="2.5.1.7" /inference="protein motif:PRIAM:2.5.1.7" /note="KEGG: glo:Glov_0818 UDP-N-acetylglucosamine 1-carboxyvinyltransferase" /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine 1-carboxyvinyltransferase" /protein_id="ZP_05428295.1" /db_xref="GI:256003304" /translation="MSKLIVTGGRKLKGEIVVEGSKNAVLPILAATVLNDGISVIKNC PKLRDVEIMLEILRKLGCKVKFEEDVVTIDSSTINSTEIPEDLATEMRSSIIFLGPLL SRFKKVTISYPGGCESLLAHFN" misc_feature complement(<1206..1520) /locus_tag="ClothDRAFT_0262" /note="This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats with a...; Region: EPT_RTPC-like; cl00288" /db_xref="CDD:185884" gene complement(1751..2860) /locus_tag="ClothDRAFT_0263" CDS complement(1751..2860) /locus_tag="ClothDRAFT_0263" /inference="protein motif:TFAM:TIGR01133" /note="TIGRFAM: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: glycosyl transferase family 28; Glycosyltransferase 28 domain; KEGG: gbm:Gbem_0491 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase" /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase" /protein_id="ZP_05428296.1" /db_xref="GI:256003305" /db_xref="InterPro:IPR004276" /db_xref="InterPro:IPR006009" /db_xref="InterPro:IPR007235" /translation="MKVIISGGGTAGHINPGLAIAKYIKKREPDTEILFIGTERGLEA RLVPRENFEIKMIKVRGFKRKLSMDTLVAVKELFQGLAEARKIIKDYKPDLVIGTGGY VCGPVLFNASRMKIPTLVHEQNAFPGVTNKILSKFVDRVAISFKEAEKYFKDKSKVVF TGNPIRSEMLEVSRETARKKLGIPKDMPLVVIFGGSRGAENINSTVAELIKRHKSDLG FYLIYATGEAQYDGIMKKIGEVKSPNINILPYIFDMANAMAAADLVVCRAGAITVSEL TALGVPSILIPSPYVTANHQEHNARALERQGASVVILEKNLRPDILYEEITTLLKDRN KLSQMAKNAKSIGITNATERIYEIIKDIMKNKAAG" misc_feature complement(1766..2860) /locus_tag="ClothDRAFT_0263" /note="undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726" /db_xref="CDD:179100" misc_feature complement(1787..2857) /locus_tag="ClothDRAFT_0263" /note="MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl...; Region: GT1_MurG; cd03785" /db_xref="CDD:99961" misc_feature complement(order(1964..1966,1973..1978,1997..1999, 2036..2038,2045..2056,2099..2101,2111..2113,2189..2191, 2273..2275,2489..2491,2825..2827)) /locus_tag="ClothDRAFT_0263" /note="active site" /db_xref="CDD:99961" misc_feature complement(order(2447..2449,2522..2524,2606..2608, 2639..2641,2648..2650)) /locus_tag="ClothDRAFT_0263" /note="homodimer interface; other site" /db_xref="CDD:99961" gene complement(2873..4024) /locus_tag="ClothDRAFT_0264" CDS complement(2873..4024) /locus_tag="ClothDRAFT_0264" /inference="protein motif:TFAM:TIGR02615" /note="TIGRFAM: stage V sporulation protein E; cell division protein FtsW; PFAM: cell cycle protein; KEGG: gbm:Gbem_0490 cell division protein FtsW" /codon_start=1 /transl_table=11 /product="stage V sporulation protein E" /protein_id="ZP_05428297.1" /db_xref="GI:256003306" /db_xref="InterPro:IPR001182" /db_xref="InterPro:IPR013437" /db_xref="InterPro:IPR013438" /translation="MKAAAIKSSTMKSAITTKKPFDFLIFLTVLIMLTIGSIMVFSSS APHAYNYMKGDSYHFLKKQLLYVPVGLFAMFVTMNIDYRKLGKLSPIIMLVSLGMLSV VWIDGIGATRNNATRWFDLGFVDFQPSEFAKLAMILFLSYSLSKRQDSLKYFFRGLVP YLILIGIHALLLLLEPHMSATIIIGLVSCVILFCAGAKIKHFVLMGVPAVAAVSYLIF TSEYRMKRVLSFLNPWEDPKGAGWQVIQSLYAIGSGGLFGRGLGNSLQKFLYIPEPYN DFILAVLAEELGFIGVALVLLLFLIFIWRGVKVSMNAPDVFGSLVAIGITSLIAFQAI INVAVVTSSMPVTGMPLPFFSYGGTSLIFLMAGVGILLNISKYANYERI" sig_peptide complement(3878..4024) /locus_tag="ClothDRAFT_0264" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.928 at residue 49" misc_feature complement(2897..3961) /locus_tag="ClothDRAFT_0264" /note="Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511" /db_xref="CDD:186047" gene complement(4105..5091) /locus_tag="ClothDRAFT_0265" CDS complement(4105..5091) /locus_tag="ClothDRAFT_0265" /inference="protein motif:TFAM:TIGR00445" /note="TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: glycosyl transferase family 4; KEGG: mca:MCA2432 phospho-N-acetylmuramoyl-pentapeptide-transferase" /codon_start=1 /transl_table=11 /product="phospho-N-acetylmuramoyl-pentapeptide- transferase" /protein_id="ZP_05428298.1" /db_xref="GI:256003307" /db_xref="InterPro:IPR000715" /db_xref="InterPro:IPR003524" /translation="MNLPFNISPHVFVFILSFAFSLILGPVLIPMLTRLKFGQTVRDD GPKTHYKKTGTPTMGGMIFLIPVTVLAAFYAGHDRRILPLIFVTLGFGLIGFIDDFIK VVKKRKDGLYWNQKMFGLLLVAVTFAVYLSHTHTSDIIIPFMGMDKTVSLGWLFVPFV VLVLIASTNAVNITDGLDGLAAGVTLIVTVFFTIVAMTRSEWEYIKMFSAMVAGGCLG FLTFNAYPARIFMGDTGSLALGGAVGAIAILMKMPLILLIVGGIYVVEALSVMIQVLS FKLTGKRVFKMAPIHHHFELSGWKEVKVVLVFWTITVLLCILGFFALRLKFY" misc_feature complement(4117..5061) /locus_tag="ClothDRAFT_0265" /note="phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108" /db_xref="CDD:178869" misc_feature complement(4126..4959) /locus_tag="ClothDRAFT_0265" /note="Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of undecaprenyl-pyrophosphoryl-N-...; Region: GT_MraY; cd06852" /db_xref="CDD:133462" misc_feature complement(4795..4800) /locus_tag="ClothDRAFT_0265" /note="Mg++ binding site; other site" /db_xref="CDD:133462" misc_feature complement(4393..4404) /locus_tag="ClothDRAFT_0265" /note="putative catalytic motif; other site" /db_xref="CDD:133462" misc_feature complement(order(4213..4227,4243..4245)) /locus_tag="ClothDRAFT_0265" /note="putative substrate binding site; other site" /db_xref="CDD:133462" gene complement(5179..6552) /locus_tag="ClothDRAFT_0266" CDS complement(5179..6552) /locus_tag="ClothDRAFT_0266" /inference="protein motif:TFAM:TIGR01143" /note="TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: gur:Gura_3978 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase" /codon_start=1 /transl_table=11 /product="UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase" /protein_id="ZP_05428299.1" /db_xref="GI:256003308" /db_xref="InterPro:IPR000713" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR005863" /db_xref="InterPro:IPR013221" /translation="MEILKCEEVVKAVGGTLISGEVNTVFYNISTDSRNIKQGDLFIP LIGERFDGHNYIASALEHGALGSLTQKETEPFPGKVLIKVSDTLKALRDLAVYYRQKF KIPFVGITGSVGKTSTKEMVAAVLSKGFKVLKNQGNFNNEIGVPLTIFNLDKSHEAAV VEMGMSGFGEISRLTSIVKPDIAIITNIGVSHIEKLGSKNNILKAKMEIFEGLNEKGL AILNGDDKLLYGLNNLLKFRTVFYGMEEGLDLRAYNVESLGEKGSTFDIEIRGKEYRV RIPVPGIHNVYNALAGIAVGIELGIPPEKIVEGIEEFSPGKMRLDIINYNGLKIINDA YNASPQSMEAAIDVLKDISGEGRTFAVLGDMLELGEFSKSAHMEVGKYAASKGIDYIV AVGEYRSNIVRGAVEAGAKEEKVFEFKDNMDAAKFLKEFVKSGDVLLVKGSRGMKMEE IVNILTG" misc_feature complement(6256..6480) /locus_tag="ClothDRAFT_0266" /note="Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225" /db_xref="CDD:144716" misc_feature complement(5188..6462) /locus_tag="ClothDRAFT_0266" /note="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143" /db_xref="CDD:162224" misc_feature complement(5665..6228) /locus_tag="ClothDRAFT_0266" /note="Mur ligase middle domain; Region: Mur_ligase_M; pfam08245" /db_xref="CDD:149357" misc_feature complement(5377..5604) /locus_tag="ClothDRAFT_0266" /note="Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875" /db_xref="CDD:145824" gene complement(6574..8031) /locus_tag="ClothDRAFT_0267" CDS complement(6574..8031) /locus_tag="ClothDRAFT_0267" /inference="protein motif:TFAM:TIGR01085" /note="TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: geo:Geob_0775 UDP-N-acetylmuramyl-tripeptide synthetase" /codon_start=1 /transl_table=11 /product="UDP-N-acetylmuramyl-tripeptide synthetase" /protein_id="ZP_05428300.1" /db_xref="GI:256003309" /db_xref="InterPro:IPR000713" /db_xref="InterPro:IPR001645" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR005761" /db_xref="InterPro:IPR013221" /translation="MKLKDLVKGLNVLEVEGDMDVEIKDIAYDSRKAKAGSLFVCIEG FKVDGHKFIPQAIENGTRAFLVQKDVDVPDDATVVRVKDTRYALASVADIFFGHPSSK FNLVGITGTKGKTTTTYMIKSILEAFGQKVGLVGTIANMIGHEVLPTDRTTPESYDLQ ELFSEMVQKNVNSVVMEVSSHALELHRVSCCEYEIGVFTNLSRDHLDFHKTFENYLNA KIKLFGMCKKGLINIDNEFGPKVVDSARCEVYTMGIDNKADLRAVDIVHHPDSVDFTV VSPWFTGDVRVNIPGKFSVYNALAAIGTCALMGVPFEYIKKGLEKVTVPGRAEVLDIK KDYTVMIDYAHSPDSLENILTTVKAYAPGRVVCVFGCGGDRDKTKRPIMGRISGQLAD FTIITSDNPRTEDPDAIIRDIEEGIKQTGGLYTTITDRREAIKYALMNAKPKDIILLA GKGHETYIILKDKTIHFDEREVVRDILKELDSGNN" misc_feature complement(6592..8031) /locus_tag="ClothDRAFT_0267" /note="UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139" /db_xref="CDD:178894" misc_feature complement(7744..7968) /locus_tag="ClothDRAFT_0267" /note="Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225" /db_xref="CDD:144716" misc_feature complement(7117..7677) /locus_tag="ClothDRAFT_0267" /note="Mur ligase middle domain; Region: Mur_ligase_M; pfam08245" /db_xref="CDD:149357" misc_feature complement(6802..7062) /locus_tag="ClothDRAFT_0267" /note="Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875" /db_xref="CDD:145824" gene complement(8109..10280) /locus_tag="ClothDRAFT_0268" CDS complement(8109..10280) /locus_tag="ClothDRAFT_0268" /EC_number="2.4.1.129" /inference="protein motif:PRIAM:2.4.1.129" /note="KEGG: gme:Gmet_0406 penicillin-binding protein, transpeptidase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; Penicillin-binding protein dimerisation domain; SMART: PASTA domain containing protein" /codon_start=1 /transl_table=11 /product="Peptidoglycan glycosyltransferase" /protein_id="ZP_05428301.1" /db_xref="GI:256003310" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /db_xref="InterPro:IPR005543" /translation="MAGTTLVMKKRLLAVLLIFTFLIIALLGRVGWLQIVRGEELQRK AYEQQNSDREIPPRRGSILDRNGKQLAISATVDRIVVNPTEIDKSPEVREQIAKKLAE FLDLDEEAVLKKINKTNSRYEIIKKRVEKSIGDQIRQWKSEEKIKGLYIDEDTKRYYP KGNLAAHVIGFVGEDNQGLDGIEKTMEKYLKGVPGKILSEVDAQGRQMPNYENKRIDP QDGLNVVLTIDENIQYFAEEALQKAIEDNKVANGAFAIVMDPRNGEILALVSKPDFNL NDPRACPPSEDPATWTGTSQKDVETLYRTVWRNKAVSDTYEPGSTFKAITTAIGFEEG VVTPETRTSDRTITVQGHNIKCWKENFHGEESFREAVYNSCNPAFVKVALDIGVDKFY NYLRAFGFYDKTGIELPGEAQGNFHAKPTDIDLAVASFGQRFKVTPLEMIAAYGAIAN GGKLIKPHLVKEIVDSEGNVVEKFEPQVVRNVISKETCQTLLDVLEGVVSEGTGRNAY VKGYRVAGKTGTSETDVEGVYVASFAAIAPADNPRICVLVALDNPRGESYYGGTIAAP VAGKIVEETLSYLGVERRYTDKDMEMIAEEVYVPDVRDKTIDEAKKILKEYGLEYRIE GDSTDGNAIIKEQTPKPGAQLAKKSVVIMYTYEPEEQIMVEVPDVTNKTIDEATKALN AAGLNIKVVGNGNAVKQSVEPGTKIPQGEVVEVEFVFLDTH" sig_peptide complement(10188..10280) /locus_tag="ClothDRAFT_0268" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.740) with cleavage site probability 0.287 at residue 31" misc_feature complement(8316..10199) /locus_tag="ClothDRAFT_0268" /note="stage V sporulation protein D; Region: spoVD_pbp; TIGR02214" /db_xref="CDD:131269" misc_feature complement(9651..10118) /locus_tag="ClothDRAFT_0268" /note="Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717" /db_xref="CDD:146381" misc_feature complement(8562..9524) /locus_tag="ClothDRAFT_0268" /note="Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01039" /db_xref="CDD:154162" misc_feature complement(8316..8486) /locus_tag="ClothDRAFT_0268" /note="PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576" /db_xref="CDD:119327" misc_feature complement(8130..8285) /locus_tag="ClothDRAFT_0268" /note="PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575" /db_xref="CDD:119326" gene complement(10481..10969) /locus_tag="ClothDRAFT_0269" CDS complement(10481..10969) /locus_tag="ClothDRAFT_0269" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: glo:Glov_0677 septum formation initiator" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428302.1" /db_xref="GI:256003311" /translation="MLEDKNYINGTAARKLVYDVYEENAVLNAKKKQRNNNKVKRKIV LCLLLVFAMGSLAMYRYSRITEMNYEIDKQLKAYNELKNENIRIKVEIENSIDIQKIK EFAEKELGMHKPDKHQITYVRVPQTDLTIVSEAAKEEEMKNAGIFSVIINKVNLLANL LY" gene complement(11408..12349) /locus_tag="ClothDRAFT_0270" CDS complement(11408..12349) /locus_tag="ClothDRAFT_0270" /inference="protein motif:TFAM:TIGR00006" /note="TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: geo:Geob_0772 S-adenosyl-methyltransferase MraW" /codon_start=1 /transl_table=11 /product="S-adenosyl-methyltransferase MraW" /protein_id="ZP_05428303.1" /db_xref="GI:256003312" /db_xref="InterPro:IPR002903" /translation="MEFQHKPVLLEETISNLAIKPDGVYIDGTVGGAGHSGEILKRLD ESGTLIGLDQDEFAIKTSQEKLAQINSKAKIILVNTNFVNIKEVCQKNNIESVDGILL DLGVSSHQLDEASRGFSYNKDAPLDMRMDRRGELTAKKIVNEYGREEIKRIIRDYGEE KWASRIAEFIVEARKKKEIETTGELVDIIKAAIPSSARRGGPHPAKRTFQALRIAVNN ELGILAKTIEDGTELLKPGGRFCIITFHSLEDRIVKDEFNKKVNPCICPKQFPVCTCG RKPEGVLVNRKPIVPKEKELEENPRARSAKLRVLEKI" misc_feature complement(11411..12343) /locus_tag="ClothDRAFT_0270" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene complement(12399..12830) /locus_tag="ClothDRAFT_0271" CDS complement(12399..12830) /locus_tag="ClothDRAFT_0271" /inference="protein motif:TFAM:TIGR00242" /note="TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: sat:SYN_01736 cell division protein" /codon_start=1 /transl_table=11 /product="MraZ protein" /protein_id="ZP_05428304.1" /db_xref="GI:256003313" /db_xref="InterPro:IPR003444" /translation="MFYGEYQHSVDAKGRVIIPSKFREGLGEKFILTKGLDNCLFAYS LEEWSNLEAKLRSLPFTDKDVRAFVRFFFAGAAEVEVDKQGRILIPQNLREYAGLEKD VYIIGVSTRVEVWDKSKWESYSGDENMSAESIAEKMAMLGI" misc_feature complement(12462..12830) /locus_tag="ClothDRAFT_0271" /note="cell division protein MraZ; Reviewed; Region: PRK00326" /db_xref="CDD:178978" misc_feature complement(12639..12830) /locus_tag="ClothDRAFT_0271" /note="MraZ protein; Region: MraZ; pfam02381" /db_xref="CDD:111290" misc_feature complement(12414..12587) /locus_tag="ClothDRAFT_0271" /note="MraZ protein; Region: MraZ; pfam02381" /db_xref="CDD:111290" gene complement(13079..14209) /locus_tag="ClothDRAFT_0272" CDS complement(13079..14209) /locus_tag="ClothDRAFT_0272" /inference="protein motif:TFAM:TIGR02210" /note="TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: sfu:Sfum_2588 rod shape-determining protein RodA" /codon_start=1 /transl_table=11 /product="rod shape-determining protein RodA" /protein_id="ZP_05428305.1" /db_xref="GI:256003314" /db_xref="InterPro:IPR001182" /db_xref="InterPro:IPR011923" /translation="MYFVEKTKNFNILKRFDYFLFSAVTLLSIIGAFVLRSAVATMPG GRRMFLVQMGSIAVGTVLALIISLLDYKDFKVLGIPFYIFTVALLVLVLFIGTGEKLG SRSWLNIMGFSFQPSELAKISMVLVSSIFLERIYDGQKNKTANMIKFFVYSGIPIALV LAQKDFGTTLVFIFAVFVMLFVSGISYKYILMLMGVAVASFPVMWFFVLNDKRKDRIR VFFNPELDPLGAGWNVIRSKIAIGSGKIFGKGLFKGIQTQNSMVPVKESDFIFSVVGE ELGFVGAIIIVALVFCILMRCLYILKNARDRYGTFVVAGITAFFAIHFIENIGMSIGL LPVTGIPLPFVSQGGSAMLTNYIAIGVVLSVSARRQKSFYSG" sig_peptide complement(14096..14209) /locus_tag="ClothDRAFT_0272" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.981) with cleavage site probability 0.469 at residue 38" misc_feature complement(13100..14161) /locus_tag="ClothDRAFT_0272" /note="Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511" /db_xref="CDD:186047" gene complement(14419..14571) /locus_tag="ClothDRAFT_0273" CDS complement(14419..14571) /locus_tag="ClothDRAFT_0273" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428306.1" /db_xref="GI:256003315" /translation="MQLKIQDLQSQLNDMIDNGDDYSKIYELSVKLDMLIVQYYNELL GRKNSN" gene complement(14754..15716) /locus_tag="ClothDRAFT_0274" CDS complement(14754..15716) /locus_tag="ClothDRAFT_0274" /inference="protein motif:TFAM:TIGR00544" /note="TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; KEGG: dat:HRM2_24910 Lgt" /codon_start=1 /transl_table=11 /product="prolipoprotein diacylglyceryl transferase" /protein_id="ZP_05428307.1" /db_xref="GI:256003316" /db_xref="InterPro:IPR001640" /translation="METVNVVKFPKLGLEFTINNVAFRIFGIPVYWYGIIIAAGFFLA VVLGLRNSEKFGIKSDDAIDLVLWGAPIAVIGARLYYVVFNWHEFNGDLKKIINIRTG GLAIYGGLIAAVITAYFFARVKKIDFLLLADLGSPYFVLAQAIGRWGNFVNQEAFGTN TNLPWGMHSEAIESYLRTLGDSSIDPAMPVHPTFLYESLWNFGVFFFLIWYRKRYRVR GELFSFYMLLYGIGRAWIEGLRTDSLYLGPFRISQVLAVVFAITFAVIIIVRHRTSKG EPVYNALGHSCDTVSDAKDFANETECDTENQNKEESVEENQGLQ" misc_feature complement(14952..15665) /locus_tag="ClothDRAFT_0274" /note="Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478" /db_xref="CDD:186023" gene complement(15734..17011) /locus_tag="ClothDRAFT_0275" CDS complement(15734..17011) /locus_tag="ClothDRAFT_0275" /inference="protein motif:PFAM:PF00675" /note="PFAM: peptidase M16 domain protein; KEGG: wsu:WS2220 putative zinc protease" /codon_start=1 /transl_table=11 /product="peptidase M16 domain protein" /protein_id="ZP_05428308.1" /db_xref="GI:256003317" /db_xref="InterPro:IPR007863" /db_xref="InterPro:IPR011765" /translation="MKVVEYKNIDETVYVHEHSSGLKSFVVPKKGYSKKYANFATHYG SINNEFVVPGEKDSIRVPDGIAHFLEHKLFEQKDGSVMDKFSQLGSNPNAYTSFAQTV YLFSCTDRFEDNFRLLLDFVQNPFITEESVEKEKDIIAQEIRMYEDDPNWRVFFNLLD AFYVNNPVKIDIAGTVESISKINRDILYKCYNTFYHPSNMMILVVGDVEPKEVFGQIE ESIDAKSSKPEIKRIFPEEPKTINRDYVEQKLAVAMPMFQMGFKDNDFNSKGIECLKR EVAVKLILEMIMGRSSSLYNELYNEGLINNTFDFDYTIEENYAYSAFGGESKDPLMVK ERVVDEIRKIQANGLDKNSYERIKRAMKGRFIKQLNSVERISHMFISVYFKDVSMFDY PDVYDNMTFDYVKEVFENHFNLDNLAVSVVNPV" misc_feature complement(15740..16996) /locus_tag="ClothDRAFT_0275" /note="Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612" /db_xref="CDD:30957" misc_feature complement(16487..>16822) /locus_tag="ClothDRAFT_0275" /note="Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675" /db_xref="CDD:144319" misc_feature complement(15929..16471) /locus_tag="ClothDRAFT_0275" /note="Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193" /db_xref="CDD:147402" gene complement(17054..18346) /locus_tag="ClothDRAFT_0276" CDS complement(17054..18346) /locus_tag="ClothDRAFT_0276" /inference="protein motif:PFAM:PF05193" /note="PFAM: peptidase M16 domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="peptidase M16 domain protein" /protein_id="ZP_05428309.1" /db_xref="GI:256003318" /db_xref="InterPro:IPR007863" /translation="MDTVISENKVSEVASFNGIKIYTIKSKKFKTNSINIFFYDDLTR ENATKNAMIPAVLRRGCEGYPTIRDISLYLEELYGSVFDCGVTKKGEHQIIQFYVEYI SNKYAQPDIDLTKKNFDLLLNIITRPVLENNAFKKEYVEQEVQNLKELIESRVNDKMQ YVIEKCLEEMCKDEPFGIYDYGSVEDLRGIDEKNLYEHYKYFLETLPVYVFISGDVDD EGIKYITDGLAKIKRGNVKSLAKTKVEVNTGEVRNIIERVSVNQGKLCLGFRTNTPPG SKDYYKLLVYNSILGGGLHSKLFQNVREKAGLAYYAFSRLEKFKGLMVVSCGIEIKNK DKALEIIYKQLDEIKNGNISDYEYEASIKSIETGIKSLKDSQLQIVDFYLSQYIAETD DTPDDVIENVKKVTKKDVVDIAERIKLDTVYFLTSKEE" misc_feature complement(17078..18298) /locus_tag="ClothDRAFT_0276" /note="Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612" /db_xref="CDD:30957" misc_feature complement(17252..17764) /locus_tag="ClothDRAFT_0276" /note="Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193" /db_xref="CDD:147402" gene 18517..18684 /locus_tag="ClothDRAFT_0277" CDS 18517..18684 /locus_tag="ClothDRAFT_0277" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428310.1" /db_xref="GI:256003319" /translation="MNQVRYYRKYQRTHSKQNEQNIAPTIDLSIAQAAGILALAFATG ILSGCLLKRLR" gene complement(18731..19669) /locus_tag="ClothDRAFT_0278" CDS complement(18731..19669) /locus_tag="ClothDRAFT_0278" /inference="protein motif:TFAM:TIGR00083" /note="TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: dvl:Dvul_2486 riboflavin biosynthesis protein RibF" /codon_start=1 /transl_table=11 /product="riboflavin biosynthesis protein RibF" /protein_id="ZP_05428311.1" /db_xref="GI:256003320" /db_xref="InterPro:IPR002606" /db_xref="InterPro:IPR015864" /db_xref="InterPro:IPR015865" /translation="MRVIYGAESNYNFTRSTGVGLGNFDGLHVGHMALIDKLIKESES NSLDSVVYTFSKHPENIIRKELFTPLITSTRKKVELLEKTRLDYLYFEKFDETFSRMR PEDFVKDILVERLNMKLAVAGFNYRFGYRGMGDTELLRKLGRKYGFRVIVIEPVMLGD EVVSSTKIRNYILEGDMERVFAFLGRHYSVAGKVEKGRRVGNTIGFPTANIYPEDYLV LPCHGVYITRTLVDGKMYHSITNVGNNPTFGGVDRISVETYIFDFEKDIYGKEIEVFF ISKIREEMRFGSVEELIEQIHKDIEIAKKVLAEDLA" misc_feature complement(19079..19621) /locus_tag="ClothDRAFT_0278" /note="FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064" /db_xref="CDD:185679" misc_feature complement(18743..19609) /locus_tag="ClothDRAFT_0278" /note="bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627" /db_xref="CDD:180171" misc_feature complement(order(19175..19183,19205..19207,19295..19297, 19577..19579,19586..19588,19595..19606)) /locus_tag="ClothDRAFT_0278" /note="active site" /db_xref="CDD:185679" misc_feature complement(18746..19123) /locus_tag="ClothDRAFT_0278" /note="Riboflavin kinase; Region: Flavokinase; pfam01687" /db_xref="CDD:145043" gene complement(19736..20629) /locus_tag="ClothDRAFT_0279" CDS complement(19736..20629) /locus_tag="ClothDRAFT_0279" /inference="protein motif:TFAM:TIGR00431" /note="TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; KEGG: pca:Pcar_1559 tRNA pseudouridine synthase B" /codon_start=1 /transl_table=11 /product="tRNA pseudouridine synthase B" /protein_id="ZP_05428312.1" /db_xref="GI:256003321" /db_xref="InterPro:IPR002501" /db_xref="InterPro:IPR014780" /translation="MNGILNVLKPPGMTSFDVVAYLRGILKIKKIGHTGTLDPGAAGV LPVCTGKATKAIEYLSDKDKVYRAELLLGVSTDTQDSYGEVIREQEVKASVEDIEKVI KSFEGDYSQLPPMYSAVKMNGKKLYELARSGIEVERTPRKVKIHFINILSIRGNRVVF DVGCSKGTYIRTLCSDVGDKLGCGGHMGFLVRLKSGSFDIKNALTLEEIKETAEKGNP EEILTSIDKVFSDYDKIYLNEKDKKRFLNGGFVTLGKYGKFALTQKVRVYDKDGAFLA LGEAVLNKSEELSLKIDKLFV" misc_feature complement(19739..20629) /locus_tag="ClothDRAFT_0279" /note="tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130" /db_xref="CDD:178886" misc_feature complement(19790..20623) /locus_tag="ClothDRAFT_0279" /note="PseudoU_synth_EcTruB: Pseudouridine synthase, Escherichia coli TruB like. This group consists of bacterial pseudouridine synthases similar to E. coli TruB and Mycobacterium tuberculosis TruB. Pseudouridine synthases catalyze the isomerization of...; Region: PseudoU_synth_EcTruB; cd02573" /db_xref="CDD:30022" misc_feature complement(order(20054..20056,20117..20134,20207..20209, 20270..20284,20432..20434,20438..20440,20450..20452, 20459..20464,20471..20473,20513..20527,20531..20539, 20573..20575,20582..20584,20588..20590)) /locus_tag="ClothDRAFT_0279" /note="RNA binding site; other site" /db_xref="CDD:30022" misc_feature complement(order(20117..20119,20516..20527)) /locus_tag="ClothDRAFT_0279" /note="active site" /db_xref="CDD:30022" gene complement(20633..21589) /locus_tag="ClothDRAFT_0280" CDS complement(20633..21589) /locus_tag="ClothDRAFT_0280" /inference="protein motif:PFAM:PF01368" /note="PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: nam:NAMH_1550 MgpA protein" /codon_start=1 /transl_table=11 /product="phosphoesterase RecJ domain protein" /protein_id="ZP_05428313.1" /db_xref="GI:256003322" /db_xref="InterPro:IPR001667" /db_xref="InterPro:IPR003156" /translation="MIENEIISLITKANKIAILPHVSADGDALGSSLALALALNTLNK KPIIYFEEDIPSIYGFLPGREFVRIYDEKPDKYELVIALDTGDLQRLGKRVEIFNDAD MTVNIDHHPTNTYFAQLNLVNTNSAAVGEMIYRLLKKMEINLDRDMATCLYVAIATDT GGFRYGNTTTVTHQITADLINNGVDVSYISQTVFETVSLPKVKLMGKAIENLELFENG KLAVIKITDDLLRSVGAKEEDCEGIVNIGRNIEGVEVAVAIRERPGGELKINFRSKNY VDVSAIANRHSGGGHKRAAGCTIKGDINDVKEMLIKEISEVL" misc_feature complement(20636..21589) /locus_tag="ClothDRAFT_0280" /note="Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618" /db_xref="CDD:30963" misc_feature complement(21122..21565) /locus_tag="ClothDRAFT_0280" /note="DHH family; Region: DHH; pfam01368" /db_xref="CDD:144819" gene complement(21640..22011) /locus_tag="ClothDRAFT_0281" CDS complement(21640..22011) /locus_tag="ClothDRAFT_0281" /inference="protein motif:TFAM:TIGR00082" /note="TIGRFAM: ribosome-binding factor A; PFAM: ribosome-binding factor A; KEGG: tgr:Tgr7_1004 ribosome-binding factor A" /codon_start=1 /transl_table=11 /product="ribosome-binding factor A" /protein_id="ZP_05428314.1" /db_xref="GI:256003323" /db_xref="InterPro:IPR000238" /translation="MERIERISEEIKREISDIIQNELKDPRLSKLISITEVNVTKDLR YAKVYVSVMGSKEEKANSLEGLKSAAGFIRREIGRRVQLRYTPEIHFELDNSIERGAY ITKLINETSAQNKGSKDPEDT" misc_feature complement(21667..21954) /locus_tag="ClothDRAFT_0281" /note="Ribosome-binding factor A; Region: RBFA; cl00542" /db_xref="CDD:186071" gene complement(22075..25215) /locus_tag="ClothDRAFT_0282" CDS complement(22075..25215) /locus_tag="ClothDRAFT_0282" /inference="protein motif:TFAM:TIGR00487" /note="TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; translation initiation factor IF-2 domain protein; Miro domain protein; GTP-binding protein HSR1-related; elongation factor Tu domain 2 protein; KEGG: gbm:Gbem_1302 translation initiation factor IF-2" /codon_start=1 /transl_table=11 /product="translation initiation factor IF-2" /protein_id="ZP_05428315.1" /db_xref="GI:256003324" /db_xref="InterPro:IPR000178" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR001806" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR004161" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006847" /db_xref="InterPro:IPR013684" /translation="MKQKSDAGVKLLAKKRVYELAKELNTTSKRLMEKLEEINIVVKN HMSFLEEDELEALYDHIGVIRHKDDKSNTDDNKTASAHSVAQHSSEAMKELKKEAKKA PRIIRTTEIYLDSKDEEIKEIKANDAKSQKKPEEKRKKNDFVRVETETSGLRPGLVRE TKPEYMRILEEQKKSEASKAQTNEKKDAEKNSVKEVVKKEEGSKQTAEIKDGSVNMEG KVLEEVKATVADSATNVNLNESIDKDKKTNDNRQVSTDNSAVNNEENAADTLNKKDMD KKNNNKKNEAKKNAEKKNEAKKNEKNDNKGGNAKKNEHRSPDMKKNDSNRPQDANKQN SKAAADKNREEGRTGSKKSLEIPKVELTTSQKEEFNSQRAERREYNKDAEKDSKRELR KEQPRSAISGGRNKNHKVIKNVFNSRKGVSEVLSDDFEMDDFYFGGSKKSRKIKKKKE EKKEEKPAPPKPVVTSIKIAAPITVKELAEALKKTSAEVIKKLMSLGIMATLNQELDF DTAAIVADEFGVKAEEEVVVSEEDILFDDSDDPNDPEAVPRPPVVVVMGHVDHGKTSL LDAIKKTNVTEKEAGGITQHIGAYMVKINNRNITFLDTPGHEAFTAMRARGAQVTDIA VLVVAADDGVMPQTIEAINHAKAANVTIIVAINKIDKPTANPEKVKQELTEYGLIPEE WGGDTIFVEVSAKKGVNIDYLLEMILLAADMLELKANPNKQAKGTVIEAKLDKDKGPV VTVLVQRGTLCVGDSIIVGTTTGRIRAMTDDKGHRIKKAGPSTPVEILGLHEVPEAGE TFYVITDEKTAKQLIEKRKLKQREQLLKASARVTLDDLFNQIKEGKVKELNIIVKADV QGSVEALKQSLEKLSNDEVRVKIIHGGVGSVTETDVTLAQVSNAIIIGFNVRPPANVI DAAKKAGVDLRLYTIIYNAIEDIEAAMKGMLEPTYKEVVIGHVEIRQIFKVSGVGTVG GGYVTDGKITRNANIRLVRDGIVVHEGKLGSLKRFKDDVREVAEGYECGLSIEKFNDI KEGDVVEVYVMEEVKE" misc_feature complement(25027..25179) /locus_tag="ClothDRAFT_0282" /note="Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760" /db_xref="CDD:147093" misc_feature complement(22123..23820) /locus_tag="ClothDRAFT_0282" /note="translation initiation factor IF-2; Region: IF-2; TIGR00487" /db_xref="CDD:161900" misc_feature complement(23653..23805) /locus_tag="ClothDRAFT_0282" /note="Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760" /db_xref="CDD:147093" misc_feature complement(23074..23550) /locus_tag="ClothDRAFT_0282" /note="IF2/eIF5B (initiation factors 2/ eukaryotic initiation factor 5B) subfamily. IF2/eIF5B contribute to ribosomal subunit joining and function as GTPases that are maximally activated by the presence of both ribosomal subunits. As seen in other GTPases...; Region: IF2_eIF5B; cd01887" /db_xref="CDD:133287" misc_feature complement(23524..23547) /locus_tag="ClothDRAFT_0282" /note="G1 box; other site" /db_xref="CDD:133287" misc_feature complement(order(23203..23205,23215..23217,23320..23325, 23392..23397,23449..23454,23500..23505,23512..23514, 23521..23526,23536..23538,23542..23544)) /locus_tag="ClothDRAFT_0282" /note="putative GEF interaction site; other site" /db_xref="CDD:133287" misc_feature complement(order(23131..23139,23233..23238,23242..23247, 23392..23394,23521..23541)) /locus_tag="ClothDRAFT_0282" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133287" misc_feature complement(23452..23472) /locus_tag="ClothDRAFT_0282" /note="Switch I region; other site" /db_xref="CDD:133287" misc_feature complement(23464..23466) /locus_tag="ClothDRAFT_0282" /note="G2 box; other site" /db_xref="CDD:133287" misc_feature complement(23398..23409) /locus_tag="ClothDRAFT_0282" /note="G3 box; other site" /db_xref="CDD:133287" misc_feature complement(23347..23403) /locus_tag="ClothDRAFT_0282" /note="Switch II region; other site" /db_xref="CDD:133287" misc_feature complement(23236..23247) /locus_tag="ClothDRAFT_0282" /note="G4 box; other site" /db_xref="CDD:133287" misc_feature complement(23131..23139) /locus_tag="ClothDRAFT_0282" /note="G5 box; other site" /db_xref="CDD:133287" misc_feature complement(22777..23046) /locus_tag="ClothDRAFT_0282" /note="This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the...; Region: IF2_mtIF2_II; cd03702" /db_xref="CDD:58093" misc_feature complement(22399..22725) /locus_tag="ClothDRAFT_0282" /note="Translation-initiation factor 2; Region: IF-2; pfam11987" /db_xref="CDD:152422" misc_feature complement(22123..22353) /locus_tag="ClothDRAFT_0282" /note="mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation...; Region: mtIF2_IVc; cd03692" /db_xref="CDD:58083" gene complement(25160..25513) /locus_tag="ClothDRAFT_0283" CDS complement(25160..25513) /locus_tag="ClothDRAFT_0283" /inference="protein motif:PFAM:PF01248" /note="PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: gbm:Gbem_1301 protein of unknown function DUF448" /codon_start=1 /transl_table=11 /product="ribosomal protein L7Ae/L30e/S12e/Gadd45" /protein_id="ZP_05428316.1" /db_xref="GI:256003325" /db_xref="InterPro:IPR004038" /translation="MLENRIYSFLGLARKANKLAAGYESCERLLKAGKAELVIVAEDA SQNTKKKFIDACNYRKVDIRIFGKKELLGKFIGKDIRSVIAVLDRGFAKRTIELIDEA KIGCGGEAIGKKESL" misc_feature complement(25214..25513) /locus_tag="ClothDRAFT_0283" /note="Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600" /db_xref="CDD:186100" gene complement(25500..25778) /locus_tag="ClothDRAFT_0284" CDS complement(25500..25778) /locus_tag="ClothDRAFT_0284" /inference="protein motif:PFAM:PF04296" /note="PFAM: protein of unknown function DUF448; KEGG: gbm:Gbem_1301 protein of unknown function DUF448" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF448" /protein_id="ZP_05428317.1" /db_xref="GI:256003326" /db_xref="InterPro:IPR007393" /translation="MKQKKIPMRMCLGCQEMKPKKELIRVVKNKENEISLDFTGKKPG RGAYICKNVSCFEKAKKGRKFERAFETSIGEEIYELLRKELEEGHAGE" misc_feature complement(25527..25760) /locus_tag="ClothDRAFT_0284" /note="Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279" /db_xref="CDD:29345" misc_feature complement(order(25635..25637,25704..25706,25752..25754)) /locus_tag="ClothDRAFT_0284" /note="putative RNA binding cleft; other site" /db_xref="CDD:29345" gene complement(25861..27075) /locus_tag="ClothDRAFT_0285" CDS complement(25861..27075) /locus_tag="ClothDRAFT_0285" /inference="protein motif:TFAM:TIGR01953" /note="KEGG: gme:Gmet_1584 transcription elongation factor NusA; TIGRFAM: transcription termination factor NusA; PFAM: NusA domain protein; RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KH domain protein" /codon_start=1 /transl_table=11 /product="NusA antitermination factor" /protein_id="ZP_05428318.1" /db_xref="GI:256003327" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR004087" /db_xref="InterPro:IPR004088" /db_xref="InterPro:IPR010213" /db_xref="InterPro:IPR013735" /translation="MSADLIHALEQLEKEKGIDKDTLIEAIEAALISAYKRSFGSSQN VKVSIDRETGDFKVYALKKVTANPQNELLEISIENAKKINPDFEENDIVEIEVTPRKF GRIAAQTAKQVVVQRIREAERGIIYNEFSNKEGEIVTGVVQRIERKNVIIDLGKAEAI LAPSEQIPGEEYKFNDRIKTYIIEVKKTTKGPQILVSRTHPGIIKRLFELEVPEIYEG IVEIKSIAREPGSRTKIAVYSKDENVDPVGACVGQKGTRVQAVVDELRGEKIDIIKWS SNPEEYISSSLSPAKVIRVDINEEEKSAKVTVPDFQLSLAIGKEGQNARLAAKLTGWK IDIKSESQLRAAIEQQLLNFNGSYSTEKQDTPITPDQLFKTNVEESSNDTVDDNAENA ADDVVEDTMDDV" misc_feature complement(26041..27075) /locus_tag="ClothDRAFT_0285" /note="transcription elongation factor NusA; Provisional; Region: nusA; PRK12327" /db_xref="CDD:183442" misc_feature complement(26707..27066) /locus_tag="ClothDRAFT_0285" /note="NusA N-terminal domain; Region: NusA_N; pfam08529" /db_xref="CDD:149546" misc_feature complement(26482..26682) /locus_tag="ClothDRAFT_0285" /note="S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and...; Region: S1_NusA; cd04455" /db_xref="CDD:88421" misc_feature complement(order(26590..26592,26596..26598,26623..26625, 26647..26649)) /locus_tag="ClothDRAFT_0285" /note="RNA binding site; other site" /db_xref="CDD:88421" misc_feature complement(order(26497..26499,26596..26598,26602..26604, 26629..26631,26641..26643)) /locus_tag="ClothDRAFT_0285" /note="homodimer interface; other site" /db_xref="CDD:88421" misc_feature complement(26062..26241) /locus_tag="ClothDRAFT_0285" /note="NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134" /db_xref="CDD:48406" misc_feature complement(26113..26124) /locus_tag="ClothDRAFT_0285" /note="G-X-X-G motif; other site" /db_xref="CDD:48406" gene complement(27163..27627) /locus_tag="ClothDRAFT_0286" CDS complement(27163..27627) /locus_tag="ClothDRAFT_0286" /inference="protein motif:PFAM:PF02576" /note="PFAM: protein of unknown function DUF150; KEGG: gsu:GSU1585 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF150" /protein_id="ZP_05428319.1" /db_xref="GI:256003328" /db_xref="InterPro:IPR003728" /translation="MTRKEIEEIVTEIANPVVNKHSFELVDVEFIKEGSSWYLRIYID KPGGITIDDCQVVSEEISDILDKEDPIPHSYFLEVSSPGLDRPLKKESDFERFKGELV EVKVFKPIEGKKIFEGELVGYKDNKIIIKKNGNELMEFERDKVALVRRVIKF" misc_feature complement(27166..27612) /locus_tag="ClothDRAFT_0286" /note="ribosome maturation protein RimP; Reviewed; Region: PRK00092" /db_xref="CDD:178857" misc_feature complement(<27274..27612) /locus_tag="ClothDRAFT_0286" /note="The eukaryotic Sm and Sm-like (LSm) proteins associate with RNA to form the core domain of the ribonucleoprotein particles involved in a variety of RNA processing events including pre-mRNA splicing, telomere replication, and mRNA degradation. Members...; Region: Sm_like; cl00259" /db_xref="CDD:185869" misc_feature complement(27166..27405) /locus_tag="ClothDRAFT_0286" /note="YxlS is a Bacillus subtilis gene of unknown function with two domains that each have an alpha/beta fold. The N-terminal domain is composed of two alpha-helices and a three-stranded beta-sheet, while the C-terminal domain is composed of one alpha-helix...; Region: YlxS_C; cd01734" /db_xref="CDD:99771" misc_feature complement(order(27235..27288,27304..27324)) /locus_tag="ClothDRAFT_0286" /note="Sm1 motif; other site" /db_xref="CDD:99771" misc_feature complement(order(27181..27198,27202..27207,27211..27219, 27241..27243,27262..27264,27280..27282,27286..27288, 27304..27309,27313..27315)) /locus_tag="ClothDRAFT_0286" /note="predicted subunit interaction site; other site" /db_xref="CDD:99771" misc_feature complement(order(27205..27207,27250..27252,27256..27258)) /locus_tag="ClothDRAFT_0286" /note="RNA binding pocket; other site" /db_xref="CDD:99771" misc_feature complement(27184..27219) /locus_tag="ClothDRAFT_0286" /note="Sm2 motif; other site" /db_xref="CDD:99771" gene complement(27979..32307) /locus_tag="ClothDRAFT_0287" CDS complement(27979..32307) /locus_tag="ClothDRAFT_0287" /EC_number="2.7.7.7" /inference="protein motif:TFAM:TIGR01405" /note="KEGG: gur:Gura_2507 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; DNA polymerase III, epsilon subunit; PFAM: DNA polymerase III alpha subunit; Exonuclease RNase T and DNA polymerase III; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: Exonuclease; phosphoesterase PHP domain protein" /codon_start=1 /transl_table=11 /product="DNA polymerase III, alpha subunit" /protein_id="ZP_05428320.1" /db_xref="GI:256003329" /db_xref="InterPro:IPR003141" /db_xref="InterPro:IPR004013" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR006054" /db_xref="InterPro:IPR006055" /db_xref="InterPro:IPR006308" /db_xref="InterPro:IPR011708" /db_xref="InterPro:IPR013520" /translation="MQSVLVKERKLSELFPEVINNENERELFDTARIQNINVYKKSRK LEIFIVSDTLIPAKTLDSVEQSFKKLFELEQVHLRVSFNVELSIEEALEKYWDSILYI VKKNIALCRGILSGCKWKIEDKKLYIYLKTKGTEILKCKSCDTLIENIIKECFGLEIK VEFKDFEIDEDKINEYIEFKENEEAKIVTDTVIKNNEKTQKTEKSEKTSGESKSNVSS AGGEKSEVIFGKNFNDSVMNMSEVTQDSGRVVVKGEIIRTEARELKSGKLLYVFDVTD FTNSLTVKIFLDKDKSGSVIERLKEKANVKIRGEAQYDKFSRELSILASDIVEVPVQV RTDNAAEKRVELHLHTQMSAMDGVTSVGELIKRAAQWGHKAIAVTDHGVVQAYPEACE AAKKNKIKVIYGIEAYLLDDSVPIVYHANGHPVDGEFVVFDIETTGLSADKDKITEIG AVKIKEGKIVDTFSTFVNPEIPIPEFVVKLTGITDDMVSDAPTIDKVLPEFLEFVGTS PLVAHNAVFDTGFIRHNARLINRNVDNPVIDTLELSRQMFPELKKHKLDVVAKHLGVS LENHHRALDDAKACGEIFIKCLEILAEKNVKTIDDIQNVFEGCWNYQKANSYHAIILV KNYVGLRNLYKIVSKTHLEYFHKRPRLPRKLLMMHREGLILGSACEAGELYRAILENK DEDEISRIVKFYDYLEIQPLGNNRFLVESGKVNSEEDLKNINRKIVALGEKYNKPVVA TCDVHFMDPQDEVFRRILMAGQGFSDADNQAPLYFRTTDEMLEEFEYLGREKCYEVVV TNTNLIADMCEDILPIPEGTFPPKIEGAEEEIRMLAENKAREIYGDPLPEIVEKRMEK ELNSIIKNGFSVMYIIAQKLVWKSLSDGYLVGSRGSVGSSFVAYLIGITEVNSLPPHY ICENCKYSEFIEDGSYGCGFDMPEKECPRCGKILKKDGYDIPFETFLGFEGDKEPDID LNFSGEYQPIAHKYTEELFGVGHVYRAGTIGTIAEKTAYGFVKNYLDERGIVATNAEI NRLVKGCTGVKRTTGQHPGGVMIVPQDREIYEFCPIQYPADDPDSGTITTHFDYHSIS GRLLKLDILGHDDPTVIKMLEDLTGVNARTIPIGEKRTMGIFSSTEPLGIRPEDINCP VGTFAIPEFGTKFVRQMLVDTKPKTFSELIRISGLSHGTDVWLNNAQDLVRNNIASLS EVICTRDDIMLNLIHYGLPNKTAFKIMEDVRKGKGLKEEYEQIMREKKVPDWYIESCK KIKYMFPKAHAAAYVMMAFRIAWFKVYYPEAFYATYFTVRADEFDASMMCHGKEKVKN KIKEYELKGNNMTQKEKNTLTILEVANEMYARGIKFLPIDIYKSDAVKFKIEKDGLRP PLNALQGLGVSAAHSIAEARNQGEFLSVDDLRIRAKVSKTVIEILQQNGCLDGLPESN QISLFG" misc_feature complement(27982..32295) /locus_tag="ClothDRAFT_0287" /note="DNA polymerase III PolC; Validated; Region: polC; PRK00448" /db_xref="CDD:179031" misc_feature complement(31729..32214) /locus_tag="ClothDRAFT_0287" /note="DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490" /db_xref="CDD:151927" misc_feature complement(31318..31566) /locus_tag="ClothDRAFT_0287" /note="polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484" /db_xref="CDD:72956" misc_feature complement(order(31324..31326,31384..31386,31390..31392, 31558..31560)) /locus_tag="ClothDRAFT_0287" /note="generic binding surface II; other site" /db_xref="CDD:72956" misc_feature complement(order(31345..31353,31372..31380,31396..31398, 31450..31452,31456..31464,31480..31482,31486..31497, 31537..31545)) /locus_tag="ClothDRAFT_0287" /note="generic binding surface I; other site" /db_xref="CDD:72956" misc_feature complement(31075..31275) /locus_tag="ClothDRAFT_0287" /note="DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481" /db_xref="CDD:128757" misc_feature complement(30553..31020) /locus_tag="ClothDRAFT_0287" /note="DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127" /db_xref="CDD:176648" misc_feature complement(order(30580..30582,30595..30597,30754..30762, 30766..30771,30994..30996,31000..31011)) /locus_tag="ClothDRAFT_0287" /note="active site" /db_xref="CDD:176648" misc_feature complement(order(30580..30582,30595..30597,30757..30762, 30766..30771,30994..30996,31000..31011)) /locus_tag="ClothDRAFT_0287" /note="substrate binding site; other site" /db_xref="CDD:176648" misc_feature complement(order(30580..30582,30595..30597,30754..30756, 31003..31005,31009..31011)) /locus_tag="ClothDRAFT_0287" /note="catalytic site; other site" /db_xref="CDD:176648" misc_feature complement(28555..29826) /locus_tag="ClothDRAFT_0287" /note="Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733" /db_xref="CDD:149024" gene complement(32325..33383) /locus_tag="ClothDRAFT_0288" CDS complement(32325..33383) /locus_tag="ClothDRAFT_0288" /EC_number="1.17.7.1" /inference="protein motif:TFAM:TIGR00612" /note="KEGG: gsu:GSU1459 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: IspG family protein" /codon_start=1 /transl_table=11 /product="1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase" /protein_id="ZP_05428321.1" /db_xref="GI:256003330" /db_xref="InterPro:IPR004588" /translation="MEYIKRKKTRKVRVGDIYIGGDAKITVQSMTNTDTRDVEATVNQ IKMLEDIGCDIIRVAVVDQEAAEAIKEIKKSIKIPLVADIHFDYRLAISSMENGADKI RLNPGNIGDRERVRKVVEVAKSRQIPIRIGVNSGSLEKNVIEKYGGITPEAMVESALQ HVRILEELDFYDIVISLKASSVPMTIAAYRLMSEKTDYPLHIGVTEAGTVFKGTIKSC AGLGCLLAEGIGDTIRVSLTGDPKEEVLVGHELLRALGIEKGGIELVSCPTCGRCQID LIGIAEKVEERLEGLDKNIKVAIMGCAVNGPGEAKEADIGIAGGKGEVLLFKKGVIVR KIPQERAVEELMEEILRM" misc_feature complement(32328..33374) /locus_tag="ClothDRAFT_0288" /note="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366" /db_xref="CDD:178989" misc_feature complement(32337..33368) /locus_tag="ClothDRAFT_0288" /note="1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Region: ispG_gcpE; TIGR00612" /db_xref="CDD:161958" gene complement(33614..34888) /locus_tag="ClothDRAFT_0289" CDS complement(33614..34888) /locus_tag="ClothDRAFT_0289" /inference="protein motif:TFAM:TIGR00054" /note="KEGG: pca:Pcar_1914 putative membrane-associated Zn-dependent protease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein" /codon_start=1 /transl_table=11 /product="membrane-associated zinc metalloprotease" /protein_id="ZP_05428322.1" /db_xref="GI:256003331" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR004387" /db_xref="InterPro:IPR008915" /translation="MRFLLVILAFDFIIIIHELGHFIVAKLSGIKVEEFSLFVGPKLF SVTIGETAYTLRLFPILAYVKMEGEEEESDSERAFNNKPVWVRAAVVAAGPLANLISA FLIISVVYYTTGYTTRTVGLVQKDSPAYNVGIREGDVIVGYDGKRIYDPLEVIQFLYV SKGKETTIEFVRNGKEIKKDIKPKVERTYQLGYYSSASGENSNVIGELIYGGALEKAG AKPGDKIVKLNDVEVESIDEIKNFLQENKNQPVKVTVLRDGNEIVFNVVPQFVENYSL GISFSRAKGGNILNVLKNGAMFTYSNIRMVPYSLYWLVTGQVSINQMTGPVGIVSTMN DVAQQSDTFKDAVLNILLWTALISAAIGATNLVPFPALDGSKLLILAIEAISRRKIPV EKEAIITSIGFIILIGLSIFVMANDIIRFIIK" misc_feature complement(33629..34888) /locus_tag="ClothDRAFT_0289" /note="RIP metalloprotease RseP; Region: TIGR00054" /db_xref="CDD:161683" misc_feature complement(<34568..34882) /locus_tag="ClothDRAFT_0289" /note="RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163" /db_xref="CDD:100084" misc_feature complement(order(34826..34828,34835..34840)) /locus_tag="ClothDRAFT_0289" /note="active site" /db_xref="CDD:100084" misc_feature complement(34340..>34522) /locus_tag="ClothDRAFT_0289" /note="PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most...; Region: PDZ_metalloprotease; cd00989" /db_xref="CDD:29046" misc_feature complement(34085..34285) /locus_tag="ClothDRAFT_0289" /note="PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most...; Region: PDZ_metalloprotease; cd00989" /db_xref="CDD:29046" misc_feature complement(33629..>33841) /locus_tag="ClothDRAFT_0289" /note="Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020" /db_xref="CDD:127338" misc_feature complement(33785..33796) /locus_tag="ClothDRAFT_0289" /note="putative substrate binding region; other site" /db_xref="CDD:100078" gene complement(35070..36215) /locus_tag="ClothDRAFT_0290" CDS complement(35070..36215) /locus_tag="ClothDRAFT_0290" /EC_number="1.1.1.267" /inference="protein motif:TFAM:TIGR00243" /note="KEGG: glo:Glov_2714 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain protein" /codon_start=1 /transl_table=11 /product="1-deoxy-D-xylulose 5-phosphate reductoisomerase" /protein_id="ZP_05428323.1" /db_xref="GI:256003332" /db_xref="InterPro:IPR003821" /db_xref="InterPro:IPR013512" /db_xref="InterPro:IPR013644" /translation="MVNRISILGSTGSIGVQTLDVARNLNIKVDGLAANKNIDLLEKQ AREFQPKIVAVKDEERARILRDRLSDTDCKVVGGVEGLKMVASIETVETVVTSIVGIA GLIPTMEAIKHKKNIALANKETLVTAGHIVMSEAARMGVKILPVDSEHSAVFQSLMGN NKKDVAKIILTASGGPFRGRKKEELRNVTLREALNHPNWSMGSKITIDSATMMNKGLE VIEAHWLFEIPQDDIEVLVHPQSIIHSMVEYKDGSIIAQLGSPDMRLPIQFALTYPDR KQNNFSKLDIVKIGSLTFEAPDLEAFPCLGLAFEALRAGGTMPAVLNAANEKAVGLFL QEKIRFLDIPEIIEKVMGRHSVKPDPDIDDIIDVDLWARKIVEEIVK" misc_feature complement(35073..36206) /locus_tag="ClothDRAFT_0290" /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447" /db_xref="CDD:180089" misc_feature complement(35829..36203) /locus_tag="ClothDRAFT_0290" /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670" /db_xref="CDD:111556" misc_feature complement(35538..35789) /locus_tag="ClothDRAFT_0290" /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436" /db_xref="CDD:149483" gene complement(36248..37084) /locus_tag="ClothDRAFT_0291" CDS complement(36248..37084) /locus_tag="ClothDRAFT_0291" /inference="protein motif:PFAM:PF01148" /note="PFAM: phosphatidate cytidylyltransferase; KEGG: sat:SYN_00917 phosphatidate cytidylyltransferase" /codon_start=1 /transl_table=11 /product="phosphatidate cytidylyltransferase" /protein_id="ZP_05428324.1" /db_xref="GI:256003333" /db_xref="InterPro:IPR000374" /translation="MLKTRVISALVGVILLIAVVCSGQMVLGTAVFFVSMLAMYEYFR SLTNAGYRPVKAVGYISCAAVLFLSWSEVLKNSFFQQIISLKSLLFAVFAMIVVLFSF IIFLHGKYNIVDISLTFFGVFYITFLLSFIVLTRNLKSGFLFVWLIFIGAFSTDTMAY FSGLFFGKHKLMPAISPKKTVEGAIGGVIGCALATFLYGLYLNKSGSIEFIPYFHFFV MGILCGIISQIGDWAASAIKRYVKVKDFGSIMPGHGGALDRFDSILFTAPVVYFYLSW II" sig_peptide complement(37013..37084) /locus_tag="ClothDRAFT_0291" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.985) with cleavage site probability 0.633 at residue 24" misc_feature complement(36263..37024) /locus_tag="ClothDRAFT_0291" /note="Cytidylyltransferase family; Region: CTP_transf_1; cl00347" /db_xref="CDD:185926" gene complement(37087..37845) /locus_tag="ClothDRAFT_0292" CDS complement(37087..37845) /locus_tag="ClothDRAFT_0292" /EC_number="2.5.1.31" /inference="protein motif:TFAM:TIGR00055" /note="KEGG: gur:Gura_3729 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase" /codon_start=1 /transl_table=11 /product="undecaprenyl diphosphate synthase" /protein_id="ZP_05428325.1" /db_xref="GI:256003334" /db_xref="InterPro:IPR001441" /translation="MGFWKNIFKAKKWKKGNIDYSKLPTHIAIIMDGNGRWAKKRALP RSMGHREGAKILKEITTFCGEIGIKYLTVYAFSTENWKRPKSEVDALMSLLLDYLKNA ETHIGGKDVRIQVIGDTSVFDDEIKKEIDRVTKLTSKNNGLILNIALNYGSRAEIVHA AKRMAKEVLEGKLKPDDINEEVLNDRLYTAKIPDPDLLIRPGGEKRLSNFLLWQSAYT ELWYTDVLWPDFKKEHIVEAILDYQRRNRRFGGI" misc_feature complement(37114..37776) /locus_tag="ClothDRAFT_0292" /note="Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475" /db_xref="CDD:29593" misc_feature complement(37750..37752) /locus_tag="ClothDRAFT_0292" /note="catalytic residue; other site" /db_xref="CDD:29593" misc_feature complement(37738..37749) /locus_tag="ClothDRAFT_0292" /note="putative FPP diphosphate binding site; other site" /db_xref="CDD:29593" misc_feature complement(order(37405..37407,37411..37413,37456..37458, 37477..37479,37558..37566,37570..37575,37615..37629)) /locus_tag="ClothDRAFT_0292" /note="putative FPP binding hydrophobic cleft; other site" /db_xref="CDD:29593" misc_feature complement(order(37186..37188,37198..37200,37207..37209, 37219..37221,37228..37233,37312..37314,37339..37341, 37348..37350,37360..37362,37384..37386)) /locus_tag="ClothDRAFT_0292" /note="dimer interface; other site" /db_xref="CDD:29593" misc_feature complement(order(37228..37230,37246..37248)) /locus_tag="ClothDRAFT_0292" /note="putative IPP diphosphate binding site; other site" /db_xref="CDD:29593" gene complement(37967..38167) /locus_tag="ClothDRAFT_0293" CDS complement(37967..38167) /locus_tag="ClothDRAFT_0293" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428326.1" /db_xref="GI:256003335" /translation="MRAENVIGFTLKEARNMLNDAGEKIASVKLTSPPKAELTDIDDY CRVIKAIDKGEEGIELIVCKPL" gene complement(38170..38721) /locus_tag="ClothDRAFT_0294" CDS complement(38170..38721) /locus_tag="ClothDRAFT_0294" /inference="protein motif:TFAM:TIGR00496" /note="TIGRFAM: ribosome recycling factor; PFAM: ribosome recycling factor; KEGG: pca:Pcar_1918 ribosome recycling factor" /codon_start=1 /transl_table=11 /product="ribosome recycling factor" /protein_id="ZP_05428327.1" /db_xref="GI:256003336" /db_xref="InterPro:IPR002661" /translation="MDEYKNIEEKMKKTVSVLKDELNTVRAGRANAAILDRITVDYYG VPTPINQLGTISVPEPRVIVIQPWDAQILKEIEKEIQKSDIGINPNNDGKVIRLVFPP LTEERRKELTKLAKKYGEDAKVAIRSIRRDGIEKMKAMKKNGEITEDDLKSAEKDIQN LTDKYIAEIDKLIEIKEKEILEV" misc_feature complement(38227..38712) /locus_tag="ClothDRAFT_0294" /note="Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are 'recycled' and ready for another round of...; Region: RRF; cd00520" /db_xref="CDD:29621" misc_feature complement(order(38413..38424,38632..38643)) /locus_tag="ClothDRAFT_0294" /note="hinge region; other site" /db_xref="CDD:29621" gene complement(38741..39448) /locus_tag="ClothDRAFT_0295" CDS complement(38741..39448) /locus_tag="ClothDRAFT_0295" /EC_number="2.7.4.22" /inference="protein motif:TFAM:TIGR02075" /note="KEGG: bba:Bd3783 hypothetical protein; TIGRFAM: uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase" /codon_start=1 /transl_table=11 /product="uridylate kinase" /protein_id="ZP_05428328.1" /db_xref="GI:256003337" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR001057" /db_xref="InterPro:IPR015963" /translation="MQKPKYKRIMLKISGEALAGEKKLGLDTDTINEISRNIKEVYDL GVEIAIVVGGGNFWRGRSGKGMDRTTADYMGMLATVINALGLQDALESQGMPTRVQTA IEMRQIAEPYIRRKAVRHLEKKRIVIFACGTGNPFFSTDTTAALRAAEIDAEVILLAK KVDGVYDSDPNINPNAKKFDKLSFMDVINKGLGVMDSTAASLCKDNNIPIIVFGLNEP GNIVKAVMGEKIGTIVM" misc_feature complement(38747..39430) /locus_tag="ClothDRAFT_0295" /note="UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control...; Region: AAK_UMPK-PyrH-Ec; cd04254" /db_xref="CDD:58620" misc_feature complement(order(38942..38947,38951..38953,38957..38959, 38966..38971,39026..39031,39284..39292,39401..39406, 39413..39415)) /locus_tag="ClothDRAFT_0295" /note="putative nucleotide binding site; other site" /db_xref="CDD:58620" misc_feature complement(order(39029..39037,39041..39046,39050..39052, 39221..39226,39233..39235,39269..39274,39284..39292)) /locus_tag="ClothDRAFT_0295" /note="uridine monophosphate binding site; other site" /db_xref="CDD:58620" misc_feature complement(order(38831..38833,38999..39004,39011..39013, 39038..39046,39050..39052,39074..39076,39092..39094, 39101..39103,39113..39115,39155..39157,39185..39187, 39206..39208,39227..39232,39254..39256)) /locus_tag="ClothDRAFT_0295" /note="homohexameric interface; other site" /db_xref="CDD:58620" gene complement(39589..40236) /locus_tag="ClothDRAFT_0296" CDS complement(39589..40236) /locus_tag="ClothDRAFT_0296" /inference="protein motif:TFAM:TIGR00116" /note="TIGRFAM: translation elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; KEGG: gsu:GSU1920 elongation factor Ts" /codon_start=1 /transl_table=11 /product="translation elongation factor Ts" /protein_id="ZP_05428329.1" /db_xref="GI:256003338" /db_xref="InterPro:IPR000449" /db_xref="InterPro:IPR001816" /db_xref="InterPro:IPR014039" /translation="MVTAEMVKELRERTGAGMMECKKALTEANGDMEKAIEILRERGL AAAAKKAGRIAAEGVVDAYIHGDGRIGVLVEINTETDFAAKNEDFRTFVKDIAMHIAA SKPEYISRDEVPAERVEKEKEILRAQALNEGKPEKIVEKMVEGRLEKFYKEICLLEQP FIKDPDKTVQQLLNEKIAIIGENINIRRFVRFERGEGIQKKEENFAEEVMKQING" misc_feature complement(39646..40236) /locus_tag="ClothDRAFT_0296" /note="elongation factor Ts; Reviewed; Region: tsf; PRK12332" /db_xref="CDD:183447" misc_feature complement(40123..40233) /locus_tag="ClothDRAFT_0296" /note="Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153" /db_xref="CDD:153548" misc_feature complement(39649..>40062) /locus_tag="ClothDRAFT_0296" /note="Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153" /db_xref="CDD:153548" gene complement(40432..41190) /locus_tag="ClothDRAFT_0297" CDS complement(40432..41190) /locus_tag="ClothDRAFT_0297" /inference="protein motif:TFAM:TIGR01011" /note="TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: pca:Pcar_1921 30S ribosomal protein S2" /codon_start=1 /transl_table=11 /product="ribosomal protein S2" /protein_id="ZP_05428330.1" /db_xref="GI:256003339" /db_xref="InterPro:IPR001865" /db_xref="InterPro:IPR005706" /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAEYIFTERNGIYIIDLQ KTVKKVEEAYYFLREVAMNGQGVLFVGTKKQAQDSIREEAQRADQYYVNARWLGGMLT NFKTIKGRINRLKELTKMEEEGVFDVLPKKEVTKLRAEKEKLEKYLGGIKEMKELPGA LFVVDPRKERIAVLEARRLGIPVVAIVDTNCDPDEVDYVIPGNDDAIRAVKLIASKMA DAIIEGRQGEQLSVESTAQEQVEETAQEETAVEA" misc_feature complement(40522..41166) /locus_tag="ClothDRAFT_0297" /note="Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425" /db_xref="CDD:100106" misc_feature complement(order(40657..40659,40666..40668,40882..40887, 40894..40902,40906..40908,41080..41088,41113..41118)) /locus_tag="ClothDRAFT_0297" /note="rRNA interaction site; other site" /db_xref="CDD:100106" misc_feature complement(order(40600..40611,40651..40653,40657..40662)) /locus_tag="ClothDRAFT_0297" /note="S8 interaction site; other site" /db_xref="CDD:100106" misc_feature complement(40540..40557) /locus_tag="ClothDRAFT_0297" /note="putative laminin-1 binding site; other site" /db_xref="CDD:100106" gene 41484..43328 /locus_tag="ClothDRAFT_0298" CDS 41484..43328 /locus_tag="ClothDRAFT_0298" /inference="protein motif:TFAM:TIGR01394" /note="TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: pca:Pcar_1211 GTP-binding protein TypA" /codon_start=1 /transl_table=11 /product="GTP-binding protein TypA" /protein_id="ZP_05428331.1" /db_xref="GI:256003340" /db_xref="InterPro:IPR000640" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR004161" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006298" /translation="MENAGEYIRENIRNVAIIAHVDHGKTTLVDAMLKQSGIFRENEQ VQERVMDSNDLERERGITILAKNTAITYKNIKINIVDTPGHADFGGEVERVLGMVDGV LLLVDSFEGTMPQTRFVLRKALQANLKPIVVINKIDRPEARPVEVVDEVLELFIELGA DDEQLDFPVVYASAREGYALYNLNDDPKNLEPLFETLINHIPAPKGFMDKPLQLLVSN IDYDDYVGRIAVGRIERGMIKTGQQAALCKKDGSIENVKISRLYVFSGLKRIEADSAM MGDIVAVSGISNINIGETICNVDAPEPLPFIEIEEPTITMTFSVNNSPFAGREGTFVT SRHLRERLFKELETNVSLRVEETDSPDSFKVSGRGELHLSILIETMRREGYEFQVSKP NVILKEIDGVLCEPVEYLIIDVPEEFMGVVMEKLGSRKAEMVNMHSSHQGYMRLEFKI PSRGLIGYRSEFLTDTKGNGIMNHIFHGFEPFKGEIPKRQRGSMVAWEDGEAVTYGLY NAQERGTLFITPGTKVYEGMIVGENSRPEDIVINVCKKKHVTNMRAAGSDEALRLTPP VILSLEQCLEFIEDDELVEVTPKNIRLRKKILDTELRAKTKARKKEQP" misc_feature 41514..42095 /locus_tag="ClothDRAFT_0298" /note="TypA (tyrosine phosphorylated protein A)/BipA subfamily. BipA is a protein belonging to the ribosome-binding family of GTPases and is widely distributed in bacteria and plants. BipA was originally described as a protein that is induced in Salmonella...; Region: TypA_BipA; cd01891" /db_xref="CDD:133291" misc_feature 41517..43298 /locus_tag="ClothDRAFT_0298" /note="GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394" /db_xref="CDD:162336" misc_feature 41538..41561 /locus_tag="ClothDRAFT_0298" /note="G1 box; other site" /db_xref="CDD:133291" misc_feature order(41541..41543,41547..41549,41559..41564,41571..41573, 41580..41585,41679..41684,41736..41741,41808..41813, 41919..41921,41931..41933) /locus_tag="ClothDRAFT_0298" /note="putative GEF interaction site; other site" /db_xref="CDD:133291" misc_feature order(41547..41564,41886..41891,41895..41897,42000..42008) /locus_tag="ClothDRAFT_0298" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133291" misc_feature 41646..41681 /locus_tag="ClothDRAFT_0298" /note="Switch I region; other site" /db_xref="CDD:133291" misc_feature 41667..41669 /locus_tag="ClothDRAFT_0298" /note="G2 box; other site" /db_xref="CDD:133291" misc_feature 41724..41735 /locus_tag="ClothDRAFT_0298" /note="G3 box; other site" /db_xref="CDD:133291" misc_feature 41730..41786 /locus_tag="ClothDRAFT_0298" /note="Switch II region; other site" /db_xref="CDD:133291" misc_feature 41886..41897 /locus_tag="ClothDRAFT_0298" /note="G4 box; other site" /db_xref="CDD:133291" misc_feature 42000..42008 /locus_tag="ClothDRAFT_0298" /note="G5 box; other site" /db_xref="CDD:133291" misc_feature 42117..42374 /locus_tag="ClothDRAFT_0298" /note="BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu. BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691" /db_xref="CDD:58082" misc_feature 42696..42932 /locus_tag="ClothDRAFT_0298" /note="BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants. BipA is a...; Region: BipA_TypA_C; cd03710" /db_xref="CDD:58063" gene 43489..44610 /locus_tag="ClothDRAFT_0299" CDS 43489..44610 /locus_tag="ClothDRAFT_0299" /inference="protein motif:PFAM:PF02618" /note="PFAM: aminodeoxychorismate lyase; KEGG: dal:Dalk_3985 aminodeoxychorismate lyase" /codon_start=1 /transl_table=11 /product="aminodeoxychorismate lyase" /protein_id="ZP_05428332.1" /db_xref="GI:256003341" /db_xref="InterPro:IPR003770" /translation="MSGNGAAVSKNKTKKRKNRLASLFLYFLVFLIIFTVSTLASYTY FINEKEINYEEVMAKIDPENGIQVEIPRGANTDDIANILREHGVIKYPFWFKFVSKFN GYDGRYKSGKHIVNKDLKYKEIMEILCSNPVTTTVTIIEGKNTDQIADILSEKKVIDK EAFLEACNTEKFDYEFLKDIPENPQRENKLEGYLFPDTYFFDPKAGERAIIEKFLDNF DAKFKPEFYERAKELNMTVDEVIILASIIERETALPEERPIVSSVFHNRLKSSDPNLK KLESCATVQYVLYKTQGKMKEKLSDEDTKIDHPYNTYLYEGLPPGPICCPGLASIEAA LYPDEESEYLYFVAKGDGSHEFSRTLAEHLEAVKKYQSN" sig_peptide 43489..43611 /locus_tag="ClothDRAFT_0299" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.895 at residue 41" misc_feature 43684..44598 /locus_tag="ClothDRAFT_0299" /note="YceG-like family; Region: YceG; pfam02618" /db_xref="CDD:145655" misc_feature 43813..44589 /locus_tag="ClothDRAFT_0299" /note="proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010" /db_xref="CDD:153433" misc_feature order(43816..43833,43858..43860,43870..43872,43891..43893, 43900..43902,44323..44325,44329..44331,44389..44391, 44398..44400,44542..44547,44566..44568,44575..44580, 44587..44589) /locus_tag="ClothDRAFT_0299" /note="dimerization interface; other site" /db_xref="CDD:153433" gene 44794..45369 /locus_tag="ClothDRAFT_0300" CDS 44794..45369 /locus_tag="ClothDRAFT_0300" /inference="protein motif:PFAM:PF01596" /note="PFAM: O-methyltransferase family 3; Methyltransferase type 11; KEGG: neu:NE1681 methyltransferase" /codon_start=1 /transl_table=11 /product="O-methyltransferase family 3" /protein_id="ZP_05428333.1" /db_xref="GI:256003342" /db_xref="InterPro:IPR002935" /db_xref="InterPro:IPR013216" /translation="MAELEEFAKENHVPIVHPEVASLLRVIGLTLRPSRVLEVGTAIG YSAILFSTFLEPGGRIDTIDRYELMLEKARANVKKAGLQDVINIIEGDALEVLKCLEH KYDMIFLDAAKGQYPEFLPECLRLLRSGGLLISDNILYKGMVAKDELVVRRKKTIVKR LRNYLETICNTDELETSILPVGDGLAISFKK" misc_feature 44797..45366 /locus_tag="ClothDRAFT_0300" /note="Predicted O-methyltransferase [General function prediction only]; Region: COG4122" /db_xref="CDD:33879" misc_feature 44896..>45129 /locus_tag="ClothDRAFT_0300" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature order(44908..44928,44983..44988,45064..45072,45121..45123) /locus_tag="ClothDRAFT_0300" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" gene 45431..46666 /locus_tag="ClothDRAFT_0301" CDS 45431..46666 /locus_tag="ClothDRAFT_0301" /inference="protein motif:PFAM:PF01136" /note="PFAM: peptidase U32; KEGG: gur:Gura_3693 peptidase U32" /codon_start=1 /transl_table=11 /product="peptidase U32" /protein_id="ZP_05428334.1" /db_xref="GI:256003343" /db_xref="InterPro:IPR001539" /translation="MKKVELLAPAGNLEKLKMAVLYGADAVYLGGEEFSLRAYAENFT LDELKAGVEFAHSKGKKVYVTINIFPHNDDLKKIPEYIKEVAGIGVDAIILSDPGILS IVKEIAPDMEIHLSTQANNTNFMSARFWHNHGVKRIILARELSLEEIREIREKTPDSL ELEVFVHGAMCISYSGRCLLSNYMAGRDSNRGLCAHPCRWKYYLMEEKRPGEYYPVYE NERGTFIFNSRDLCMIEHIPELVESGVSSFKIEGRMKSSFYVATVVKAYREAIDAYYE DKDNYKFDPRLLEEVCKVSHREFTTGFFFNKPGPKDQIYATSSYIREYDFVGVVQKYD KATKIATVEQRNRMYKGEEIEVVNPKGNFFVQKIEWMKNADGEDIDVAPHPQMTVYMP MKEDVEEFAMLRRKSSPNK" misc_feature 45431..46645 /locus_tag="ClothDRAFT_0301" /note="putative protease; Provisional; Region: PRK15452" /db_xref="CDD:185349" misc_feature <45431..45724 /locus_tag="ClothDRAFT_0301" /note="Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl12019" /db_xref="CDD:187164" misc_feature order(45551..45553,45623..45628,45710..45712,45716..45721) /locus_tag="ClothDRAFT_0301" /note="active site" /db_xref="CDD:29612" misc_feature 45653..46357 /locus_tag="ClothDRAFT_0301" /note="Peptidase family U32; Region: Peptidase_U32; cl03113" /db_xref="CDD:186550" gene 46964..48619 /locus_tag="ClothDRAFT_0302" CDS 46964..48619 /locus_tag="ClothDRAFT_0302" /EC_number="2.4.1.129" /inference="protein motif:PRIAM:2.4.1.129" /note="PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: gbm:Gbem_2460 penicillin-binding protein 2" /codon_start=1 /transl_table=11 /product="Peptidoglycan glycosyltransferase" /protein_id="ZP_05428335.1" /db_xref="GI:256003344" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /translation="MFIKRNKIILAVFTLSIILLFSRVIYIQFILGEKLFIQATAQKV SELTVDVPRGNILDRNLIPLTNRKKKVDVVIQPLYLKDNSSDLQKISNILGLNFNEIK RQVEIKKEPIKITIDENKKETLIKEKVQGISFIHSLERYDENTLAKHVLGYLNKIDIR GETGIEKAYDSYLKLNSKSSVAVITDARDNPVKGLGYRFINSAKTGKMLNVKLTIDYN IQKTAEEVMDKYNLKGAVVIEEVSSGDIVAMVSKPDFNPNEIEKYLDSPDNELFNRAV ASYNLGSIFKIIDLACAYSKNINPSMYYFCPGYVILGDKEFRCSAYGKGGHGLIDLHE AFASSCNPYFIELGIKIGPNNIIETANKFGFGKITGIDSQGVEESAGNLPKTGSFTYG DTANISIGQGDVLATPLQVADMVATIANGGIKNNVNIVDSIVDSKGNTVKVIRKDKGE RIIEKEVCDKIKQLMEEVTVSGTGTRANLSEYGGAGGKTGSAETGQFINGEKVVHAWF AGYFPRLDPKYSVAVFIEDGKSGGAIAAPVFEEIAKTILKKGL" misc_feature 46973..48604 /locus_tag="ClothDRAFT_0302" /note="penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423" /db_xref="CDD:163256" misc_feature 47108..47551 /locus_tag="ClothDRAFT_0302" /note="Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717" /db_xref="CDD:146381" misc_feature 47663..48595 /locus_tag="ClothDRAFT_0302" /note="Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01039" /db_xref="CDD:154162" gene 48698..49408 /locus_tag="ClothDRAFT_0303" CDS 48698..49408 /locus_tag="ClothDRAFT_0303" /inference="protein motif:TFAM:TIGR02846" /note="TIGRFAM: RNA polymerase sigma-K factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: noc:Noc_1702 RpoS" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma 28 subunit, SigK" /protein_id="ZP_05428336.1" /db_xref="GI:256003345" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR014209" /db_xref="InterPro:IPR014284" /translation="MFYILISSVFEILNNIFFLLGYISNVNSFPQPLSPEEEQHYLDL LKKGDEEARNILIERNLRLVAHIVKKYSSTINDSDDLISIGTIGLIKAISTFNHEKGT RLATYAARCIENEILMHIRSNKKTQSEVSLQDPIGVDRDGNEIALIDVIGNESESVVE EVELKMQVKRLYNKMKDVLKAREKMVLELRYGLLNGTGKTQREIAKMLGISRSYVSRI EKKAIKKLGKELKSESFK" misc_feature 48701..49348 /locus_tag="ClothDRAFT_0303" /note="sporulation sigma factor SigK; Reviewed; Region: PRK05803" /db_xref="CDD:180266" misc_feature 48863..49075 /locus_tag="ClothDRAFT_0303" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature 49226..>49348 /locus_tag="ClothDRAFT_0303" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cl01055" /db_xref="CDD:186312" gene complement(49473..50555) /locus_tag="ClothDRAFT_0304" CDS complement(49473..50555) /locus_tag="ClothDRAFT_0304" /inference="protein motif:TFAM:TIGR02872" /note="TIGRFAM: sporulation integral membrane protein YtvI; PFAM: protein of unknown function UPF0118; KEGG: rco:RC0978 putative permease PerM-like protein" /codon_start=1 /transl_table=11 /product="sporulation integral membrane protein YtvI" /protein_id="ZP_05428337.1" /db_xref="GI:256003346" /db_xref="InterPro:IPR002549" /db_xref="InterPro:IPR014227" /translation="MDKRIKLVIRLVLIFGGTVIGILLGLRLAIYFAPFLIAFAISSM IEPVVRFLMKKLKFRRKFAALVSLLLGLSMIAILLLMLFSKLYNEITSLSSSQPEFWK EAYQNISNLINRGLNIYFGLPSEVTAQISNMVSSLSNSVSSLVDSFVKGIYNTAISIP QMVIFIFVTILSTYFISSDRDRIYDYIKDNVPDALLNKIIDIKDSMFTALFGYVKAQL ILMTITFCELSLGFTIIGVKRPILLGLVISFIDAFPVLGTGGVLVPWAIYEFLTKDIR MGVSLLILYVIVLVIRQMIEPKVVGEQIGLHPLMTLITMYLGMKFFGLPGLILGPIVT LIFKNIISGMIKHKNLKELINEFIKK" misc_feature complement(49533..50528) /locus_tag="ClothDRAFT_0304" /note="Domain of unknown function DUF20; Region: UPF0118; cl00465" /db_xref="CDD:186015" gene complement(50885..53266) /locus_tag="ClothDRAFT_0305" CDS complement(50885..53266) /locus_tag="ClothDRAFT_0305" /inference="protein motif:TFAM:TIGR01069" /note="KEGG: pca:Pcar_2680 mismatch repair ATPase; TIGRFAM: MutS2 family protein; PFAM: Smr protein/MutS2; DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; Smr protein/MutS2" /codon_start=1 /transl_table=11 /product="MutS2 family protein" /protein_id="ZP_05428338.1" /db_xref="GI:256003347" /db_xref="InterPro:IPR000432" /db_xref="InterPro:IPR002625" /db_xref="InterPro:IPR005747" /db_xref="InterPro:IPR007696" /translation="MNEKTLKILEFNKIIDKLVSLATSSLGKELAEKLVPDTDLNRVE RAQKETSDAVAFIARRGTPPMGGIHDIRDSLKRVEIGAILNPGELLKTADVLRAVRNL KSYASNDRIKTDEDNIVSELIGCLESNKRIEDRIYMSILSEDEIADNASPTLANIRRQ IRNAQESIKDKLNDIIRSSRYQKYIQEPIVTLRGDRYVIPVKQEYRTEIPGLIHDSSA SGATIFIEPMAVVEANNHIRELKIKEQAEIEKILGELTGEIRGIVDSLKSNVSILGRL DFIFAKARLSLDYNCVCPVLNDEHKILIKKGRHPLLDKKTVVPIDFWIGEDFNTLVVT GPNTGGKTVTLKTVGLFTLMTQAGLHIPANEGTKMSIFKKVYADIGDEQSIEQSLSTF SSHMKNIVGILKDVDEDSLVLFDELGAGTDPTEGAALAMSILEYLRNKGSTTVATTHY SQLKAYAVTTKFVENACCEFNVETLRPTYRLLIGVPGKSNAFAISKRLGLFDDIIEKA KEFLTQDDIKFEDMLMSIEKNLNQSENEKMKAESYRLEAEKLKKELEEQKRKLAENRE RLIQEARAEARKILLEARKEAEEIISKMRRLEQEVHNAQRQKEAEELRLKLKRKVDSI EETLELPLAPKNALVKPPENLKPGDSVLIVNLDQKGTIITPPDKDGEVVVQAGIMKIN VHISNLKLVDEQKIVLSNSGIGKIGMSKAKSISTEIDVRGYNLEEAIESVDKYLDDAY LSGLTEVSIIHGKGTGVLRSGIQKFLKSDSRVKSFRLGKYGEGESGVTIVELR" misc_feature complement(50888..53266) /locus_tag="ClothDRAFT_0305" /note="recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409" /db_xref="CDD:179009" misc_feature complement(51767..52357) /locus_tag="ClothDRAFT_0305" /note="MutS2 homologs in bacteria and eukaryotes. The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also...; Region: ABC_MutS2; cd03280" /db_xref="CDD:73039" misc_feature complement(52241..52264) /locus_tag="ClothDRAFT_0305" /note="Walker A/P-loop; other site" /db_xref="CDD:73039" misc_feature complement(order(51920..51922,52019..52024,52127..52129, 52238..52246,52250..52255)) /locus_tag="ClothDRAFT_0305" /note="ATP binding site; other site" /db_xref="CDD:73039" misc_feature complement(52127..52138) /locus_tag="ClothDRAFT_0305" /note="Q-loop/lid; other site" /db_xref="CDD:73039" misc_feature complement(52073..52114) /locus_tag="ClothDRAFT_0305" /note="ABC transporter signature motif; other site" /db_xref="CDD:73039" misc_feature complement(52019..52036) /locus_tag="ClothDRAFT_0305" /note="Walker B; other site" /db_xref="CDD:73039" misc_feature complement(52001..52012) /locus_tag="ClothDRAFT_0305" /note="D-loop; other site" /db_xref="CDD:73039" misc_feature complement(51914..51934) /locus_tag="ClothDRAFT_0305" /note="H-loop/switch region; other site" /db_xref="CDD:73039" misc_feature complement(50888..51115) /locus_tag="ClothDRAFT_0305" /note="Smr domain; Region: Smr; cl02619" /db_xref="CDD:186529" gene 53496..53708 /locus_tag="ClothDRAFT_0306" CDS 53496..53708 /locus_tag="ClothDRAFT_0306" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428339.1" /db_xref="GI:256003348" /translation="MTNEKKLEIIRSYIEEIKAYEESQDLPFSKKQHLKRAREAYMNL YRDAEKGKLDPDLLHENITSFMYMLQ" gene complement(53762..54184) /locus_tag="ClothDRAFT_0307" CDS complement(53762..54184) /locus_tag="ClothDRAFT_0307" /inference="similar to AA sequence:KEGG:Dalk_3712" /note="KEGG: dal:Dalk_3712 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428340.1" /db_xref="GI:256003349" /db_xref="InterPro:IPR002347" /translation="MKIAVVDGQGGGIGKAVVEKLRKELPEDTQIIALGTNALATTLM LKAGANEGASGENAIVFNAPKVDIIVGPIGIISANSMMGELTPLMAAAIAESPARKIL IPLNRCNIEIAGVKNEPLPYYIEHAVEMVKKYVEGHIA" misc_feature complement(<54113..>54181) /locus_tag="ClothDRAFT_0307" /note="short chain dehydrogenase; Validated; Region: PRK08324" /db_xref="CDD:181389" gene complement(54558..55616) /locus_tag="ClothDRAFT_0308" CDS complement(54558..55616) /locus_tag="ClothDRAFT_0308" /inference="protein motif:PFAM:PF01520" /note="PFAM: cell wall hydrolase/autolysin; copper amine oxidase domain protein; SMART: cell wall hydrolase/autolysin; KEGG: pca:Pcar_1511 N-acetylmuramoyl-L-alanine amidase" /codon_start=1 /transl_table=11 /product="cell wall hydrolase/autolysin" /protein_id="ZP_05428341.1" /db_xref="GI:256003350" /db_xref="InterPro:IPR002508" /db_xref="InterPro:IPR012854" /translation="MKKPVILLTVLILVILMTVPGFAANGQYYSGYWGVTSNALIAVN GKVLTLERNPVIIEGRILVPARTTFQVLGVTTEWYSSSGVVKMVKGNKAVKMTVGSKV AHSGGSVKYMEAPPILVNGTVMVPMRFVAETFGENVGWDAKNEMAYIGNKPAEIPSRS GLKSNRTYKVVIDAGHGGSQSGAVYGGVKEKDLNLDIAKRLNTLLKAEGIKTYMTREK DITVGLYTRSDLANKEKADLFVSIHNNAGNSKTSGSMTLYHPDSGKKKGNLTAYEFAQ IVQKNLNKTLGSKNMGVIQRPNLAVLRTTNMPAVIAEIGYMSNSAELAKLKTDSYRQK AAEALRDAVIESLEKMYK" sig_peptide complement(55545..55616) /locus_tag="ClothDRAFT_0308" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 at residue 24" misc_feature complement(55170..55448) /locus_tag="ClothDRAFT_0308" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature complement(54582..55220) /locus_tag="ClothDRAFT_0308" /note="N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860" /db_xref="CDD:31201" misc_feature complement(54585..55112) /locus_tag="ClothDRAFT_0308" /note="N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696" /db_xref="CDD:119407" misc_feature complement(order(54678..54680,54888..54890,55047..55049, 55089..55091)) /locus_tag="ClothDRAFT_0308" /note="active site" /db_xref="CDD:119407" misc_feature complement(order(54888..54890,55047..55049,55089..55091)) /locus_tag="ClothDRAFT_0308" /note="metal-binding site" /db_xref="CDD:119407" gene complement(56348..57217) /locus_tag="ClothDRAFT_0309" CDS complement(56348..57217) /locus_tag="ClothDRAFT_0309" /inference="protein motif:PFAM:PF00528" /note="PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_0352 binding-protein-dependent transport systems inner membrane component" /codon_start=1 /transl_table=11 /product="binding-protein-dependent transport systems inner membrane component" /protein_id="ZP_05428342.1" /db_xref="GI:256003351" /db_xref="InterPro:IPR000515" /translation="MAKIGYFESMKRKKKIKDTIANIILAILVVLTLGPIVFMVLTSL MDHNAIARGKWIAPTRFSNYVEVFQKLPFGIYFRNSLIVCSIVMVVALVIATLAGYSL AKYKFPGSGFFGILILATQLLPGMMFLLPLYLDFVKIKQATGIQLINSIPGLVIVYSA FFVPFSIWIIRGFFASIPGELEEAARIDGCNKFTAFLRVMLPLAVPGIVATAIYIFLT AWDELIFAWVLLKDTKVTTIPAGIRGFIAYTTARYDLLMAAGTIVTIPVLIMFFTMQK KFISGMTAGAVKG" sig_peptide complement(57089..57217) /locus_tag="ClothDRAFT_0309" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.611) with cleavage site probability 0.317 at residue 43" misc_feature complement(56414..56989) /locus_tag="ClothDRAFT_0309" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature complement(order(56414..56419,56426..56431,56438..56443, 56447..56452,56459..56464,56492..56497,56534..56539, 56546..56557,56576..56578,56585..56590,56630..56632, 56681..56683,56690..56695,56705..56707,56711..56716, 56723..56725,56729..56731,56735..56740,56819..56821, 56825..56830,56837..56866,56870..56881,56909..56911, 56924..56929,56936..56941)) /locus_tag="ClothDRAFT_0309" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature complement(order(56540..56557,56819..56863)) /locus_tag="ClothDRAFT_0309" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature complement(order(56462..56464,56492..56494,56501..56503, 56537..56539,56753..56755,56819..56821)) /locus_tag="ClothDRAFT_0309" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature complement(order(56609..56611,56621..56626,56642..56680)) /locus_tag="ClothDRAFT_0309" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" gene complement(57217..58200) /locus_tag="ClothDRAFT_0310" CDS complement(57217..58200) /locus_tag="ClothDRAFT_0310" /inference="protein motif:PFAM:PF00528" /note="PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bba:Bd1227 maltose/maltodextrin transport permease homologue" /codon_start=1 /transl_table=11 /product="binding-protein-dependent transport systems inner membrane component" /protein_id="ZP_05428343.1" /db_xref="GI:256003352" /db_xref="InterPro:IPR000515" /translation="MDIQLKKSGIGVKEKKSKNHLLYSIKQNLFAYAMLIPTFVCMMC IHFIPMLQGIYMSLLDLNQLTMTKFLNAPFIGLKNYYEILFDEKSLIRRGFWFALRNT AIYTVVVTFATFALGIILAMLVNREFKGRGIVRTALLMPWVVPSYVVGMTWGFLWRQD SGLINIILCDILHILPEKPYWLVGPNQIWAIIIPTIWRGLPLSMILMLAGLQSISPDY YEAADIDGANGWQKFWHITLPLLKPILAINVMFSLISNIYSFNIVSMMFGNGAGIPGE WGDLLMTYIQRNTFQMWRFGPGAAALMIVMFFVLGIVALWYTLFKDDLVVK" misc_feature complement(57271..57906) /locus_tag="ClothDRAFT_0310" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature complement(order(57271..57276,57283..57288,57295..57300, 57304..57309,57316..57321,57349..57354,57406..57411, 57418..57429,57448..57450,57457..57462,57502..57504, 57553..57555,57562..57567,57577..57579,57583..57588, 57595..57597,57601..57603,57610..57615,57739..57741, 57745..57750,57757..57786,57790..57801,57826..57828, 57841..57846,57853..57858)) /locus_tag="ClothDRAFT_0310" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature complement(order(57412..57429,57739..57783)) /locus_tag="ClothDRAFT_0310" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature complement(order(57319..57321,57349..57351,57358..57360, 57409..57411,57628..57630,57739..57741)) /locus_tag="ClothDRAFT_0310" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature complement(order(57481..57483,57493..57498,57514..57552)) /locus_tag="ClothDRAFT_0310" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" gene complement(58352..59731) /locus_tag="ClothDRAFT_0311" CDS complement(58352..59731) /locus_tag="ClothDRAFT_0311" /inference="protein motif:PFAM:PF01547" /note="PFAM: extracellular solute-binding protein family 1; KEGG: oan:Oant_3895 extracellular solute-binding protein family 1" /codon_start=1 /transl_table=11 /product="extracellular solute-binding protein family 1" /protein_id="ZP_05428344.1" /db_xref="GI:256003353" /db_xref="InterPro:IPR006059" /translation="MLKKVIALMLVAVMALSLAACGGGGGNTTTSPQPNDSQNSPDSG TKKDPVKLTMWIMPNSDTPDQDLLKVVKPFTDANPHITVEPTVVDWSAALTKITAAAT SGEAPDITQVGSTWTAAIGAMEGALVELTGKIDTSAFVESTLQSAYIKGTDKMFGMPW FTETRALFYRKDACEKAGVNPETDFATWDKFKDALKKLNGIEVDGKKLAALGMPGKND WNVVHNFSWWIYGAGGDFVNEEGTQATFSSENALKGIKFYSELAVEGLMDEPSLEKNT SDIESAFGDGAYATAFMGPWVISSYTKNKEENGNDLIDKIGVTMVPEGPAGRYAFMGG SNLVIFNSSKNKDEALELLKFFASKEAQVEYSKVSKMLPVVKAAYEDPYFEDSLMKVF KEQVDKYGKHYASVPGWASAEVIFSEGLSKIWDNVMEVDGAYSYDKTVQIVKDVESQI NQILQETSK" sig_peptide complement(59663..59731) /locus_tag="ClothDRAFT_0311" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.525 at residue 23" misc_feature complement(58364..59608) /locus_tag="ClothDRAFT_0311" /note="ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653" /db_xref="CDD:31839" misc_feature complement(58646..59548) /locus_tag="ClothDRAFT_0311" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398" /db_xref="CDD:187020" gene complement(60413..61891) /locus_tag="ClothDRAFT_0312" CDS complement(60413..61891) /locus_tag="ClothDRAFT_0312" /inference="protein motif:TFAM:TIGR02836" /note="TIGRFAM: stage IV sporulation protein A; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="stage IV sporulation protein A" /protein_id="ZP_05428345.1" /db_xref="GI:256003354" /db_xref="InterPro:IPR014201" /translation="MEKYNIYQQIAERTQGDIYIGVVGPVRTGKSTFIKRFMDLLVIP NIENEFSRARAKDELPQSASGRTIMTTEPKFVPNEAIKIELDENVHFKVRLVDCVGYM VKGAIGHMENDMPRMVSTPWFDEQIPFVQAAEIGTKKVITDHSTIGFVVTTDGSITDI AREDYVEAEERVVKELKEINKPFVILLNSINPSNPETESLRQELEAKYNVPVIGVNCA QLRIEDLNNIMERVLLEFPINEIGVNIPKWIESLDDNHWLKVDIINAVKEAFRGITRI REIRGSVNRFDEFEFIKRAYIDHINLGSGTAYVEINEQDGLFYRILSEMTGLEIDGEH RLISLMTELARIKKEYDKVQYALHEVKLKGYGIVSPQIEEMSLEEPEIIKQGSRFGVK LRASAPSIHMIRADIETEIAPLVGTEKQSEELVSYLLKEFENEPEKLWQSNIFGKSLH ELVSEGLQNKLYRMPEDAQLKLQETLQKIINEGSGGLICIIL" misc_feature complement(60416..61891) /locus_tag="ClothDRAFT_0312" /note="Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; cl09772" /db_xref="CDD:158689" gene complement(62238..63257) /locus_tag="ClothDRAFT_0313" CDS complement(62238..63257) /locus_tag="ClothDRAFT_0313" /EC_number="1.1.1.94" /inference="protein motif:PRIAM:1.1.1.94" /note="PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; Ketopantoate reductase ApbA/PanE domain protein; UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: gme:Gmet_0008 NAD-dependent glycerol-3-phosphate dehydrogenase-like" /codon_start=1 /transl_table=11 /product="Glycerol-3-phosphate dehydrogenase (NAD(P)(+))" /protein_id="ZP_05428346.1" /db_xref="GI:256003355" /db_xref="InterPro:IPR001732" /db_xref="InterPro:IPR004455" /db_xref="InterPro:IPR006109" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR006168" /db_xref="InterPro:IPR011128" /db_xref="InterPro:IPR013332" /translation="MNKKISIIGAGSWGTALAVLLANNGMSVTMWSIFEDEIKMLNEK REHVHKLPGVIVPENVTFTSDLEKAVCDAEVVVVVVPSQTVRQTAKDISKYIRDDTVI VSCSKGLEEGTGLRMSEVIGQEIKDAKTVILSGPSHAEEVGRGVPTAIVAASCDIKAA ELIQDIFMSPEFRVYTNTDVVGVELGGALKNVIALCAGISDGLGFGDNTKAALMTRGI TEISRLGVSMGANPQTFAGLTGIGDLIVTCTSMHSRNRRAGILIGQGKSPQEAMDEVK MVVEGVTTTKAAYELARKMDVAMPITFEAYEVLFNGKNPRQAVYDLMMRNKKNEVEEL DAKWL" sig_peptide complement(63201..63257) /locus_tag="ClothDRAFT_0313" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.302 at residue 19" misc_feature complement(62283..63251) /locus_tag="ClothDRAFT_0313" /note="NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094" /db_xref="CDD:178859" misc_feature complement(62775..63251) /locus_tag="ClothDRAFT_0313" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" misc_feature complement(62292..62726) /locus_tag="ClothDRAFT_0313" /note="NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479" /db_xref="CDD:116100" gene complement(63271..63921) /locus_tag="ClothDRAFT_0314" CDS complement(63271..63921) /locus_tag="ClothDRAFT_0314" /inference="protein motif:PFAM:PF02660" /note="PFAM: protein of unknown function DUF205; KEGG: gur:Gura_3922 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF205" /protein_id="ZP_05428347.1" /db_xref="GI:256003356" /db_xref="InterPro:IPR003811" /translation="MVWPVLKAVVAALIGYLLGSANTSLIVGKFYGVDVRKHGSGNAG MTNTLRTLGKFPAFLVILGDTLKGILACVIGYYIFKIGFDSSELNFTVELDRAGLLAG GLGAILGHNWPLYFGFKGGKGVLTTFAVIMLAGPYQGLILLGVFLVVVVLTRYVSLGS ITAALCFPFLVAFMEKDIIYIVFAVFVSLLVIIRHRSNIVRLCKGTENKLGAKKNE" misc_feature complement(63316..63885) /locus_tag="ClothDRAFT_0314" /note="Domain of unknown function (DUF205); Region: DUF205; cl00410" /db_xref="CDD:185978" gene complement(63927..65249) /locus_tag="ClothDRAFT_0315" CDS complement(63927..65249) /locus_tag="ClothDRAFT_0315" /inference="protein motif:TFAM:TIGR00231" /note="TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Miro domain protein; KEGG: ppd:Ppro_1727 GTP-binding protein EngA" /codon_start=1 /transl_table=11 /product="small GTP-binding protein" /protein_id="ZP_05428348.1" /db_xref="GI:256003357" /db_xref="InterPro:IPR001806" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR013684" /translation="MPKPVVAVVGRPNVGKSTFFNYLVGKRISIVEDTPGVTRDRIYA EVEWRNKKFTLIDTGGIEPYSEDKIMQQMKRQAEIAIETADIIIFMVDVKDGVTASDK EVATLLRKTKKPVIVAVNKVDKIGELPADFYEFYNLGFGELMAISSIHGLGMGDLLDE IFKYFPEEDAEDYDEDVIKVAVVGKPNVGKSSLINRILGEERVIVSDIPGTTRDAIDT FVENEHGKFVFIDTAGIRRQSKINEKIEKYSIIRSWTAIERADVCLILIDAKEGVTEQ DTKIAGYAHEQGKASIIVVNKWDLIEKQTGTLEEYRRTVHEKLGFMLYAPVIFISALT GQRVDRIYGLIKHVADQAAMRISTGVLNDLLNEATAMVQPPSDKGKRLKIYYMTQSSV KPPSFVLFINNMELMHYSYERYLENQLRKSFGFEGTPIKFILREKEKE" misc_feature complement(63930..65243) /locus_tag="ClothDRAFT_0315" /note="GTP-binding protein Der; Reviewed; Region: PRK00093" /db_xref="CDD:178858" misc_feature complement(64755..65231) /locus_tag="ClothDRAFT_0315" /note="EngA1 subfamily. This CD represents the first GTPase domain of EngA and its orthologs, which are composed of two adjacent GTPase domains. Since the sequences of the two domains are more similar to each other than to other GTPases, it is likely that...; Region: EngA1; cd01894" /db_xref="CDD:133294" misc_feature complement(65199..65222) /locus_tag="ClothDRAFT_0315" /note="G1 box; other site" /db_xref="CDD:133294" misc_feature complement(order(64803..64811,64881..64883,64887..64892, 65196..65207,65211..65213)) /locus_tag="ClothDRAFT_0315" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133294" misc_feature complement(order(65127..65138,65148..65168)) /locus_tag="ClothDRAFT_0315" /note="Switch I region; other site" /db_xref="CDD:133294" misc_feature complement(65136..65138) /locus_tag="ClothDRAFT_0315" /note="G2 box; other site" /db_xref="CDD:133294" misc_feature complement(order(64998..65003,65067..65084)) /locus_tag="ClothDRAFT_0315" /note="Switch II region; other site" /db_xref="CDD:133294" misc_feature complement(65070..65081) /locus_tag="ClothDRAFT_0315" /note="G3 box; other site" /db_xref="CDD:133294" misc_feature complement(64881..64892) /locus_tag="ClothDRAFT_0315" /note="G4 box; other site" /db_xref="CDD:133294" misc_feature complement(64803..64811) /locus_tag="ClothDRAFT_0315" /note="G5 box; other site" /db_xref="CDD:133294" misc_feature complement(64206..64724) /locus_tag="ClothDRAFT_0315" /note="EngA2 subfamily. This CD represents the second GTPase domain of EngA and its orthologs, which are composed of two adjacent GTPase domains. Since the sequences of the two domains are more similar to each other than to other GTPases, it is likely that...; Region: EngA2; cd01895" /db_xref="CDD:133295" misc_feature complement(64677..64700) /locus_tag="ClothDRAFT_0315" /note="G1 box; other site" /db_xref="CDD:133295" misc_feature complement(order(64251..64259,64353..64355,64359..64364, 64674..64685,64689..64691)) /locus_tag="ClothDRAFT_0315" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133295" misc_feature complement(order(64605..64646,64653..64655)) /locus_tag="ClothDRAFT_0315" /note="Switch I region; other site" /db_xref="CDD:133295" misc_feature complement(64614..64616) /locus_tag="ClothDRAFT_0315" /note="G2 box; other site" /db_xref="CDD:133295" misc_feature complement(64548..64559) /locus_tag="ClothDRAFT_0315" /note="G3 box; other site" /db_xref="CDD:133295" misc_feature complement(order(64470..64475,64545..64550)) /locus_tag="ClothDRAFT_0315" /note="Switch II region; other site" /db_xref="CDD:133295" misc_feature complement(64353..64364) /locus_tag="ClothDRAFT_0315" /note="G4 box; other site" /db_xref="CDD:133295" misc_feature complement(64251..64259) /locus_tag="ClothDRAFT_0315" /note="G5 box; other site" /db_xref="CDD:133295" gene complement(65299..66621) /locus_tag="ClothDRAFT_0316" CDS complement(65299..66621) /locus_tag="ClothDRAFT_0316" /inference="protein motif:PFAM:PF04459" /note="PFAM: protein of unknown function DUF512; KEGG: ppd:Ppro_2966 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF512" /protein_id="ZP_05428349.1" /db_xref="GI:256003358" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR007549" /translation="MKYRPVPIKRVLPGSIAQESDLQEGDLILSINGQKISDIFDYRF LIADENLVLEVQKKNGEIWEIEIEKDEYEDLGIEFENLMIDDTKSCRNKCIFCFIDQL PKGMRETLYFKDDDSRLSFFMGNYVTLTNMSYDDIDRIIKYKMSPINVSVHTSNPELR VYMLRNKTAGDVMDKIKRLIEGGIKVNAQIVLVRGVNDGKELDRTLKDLSALYPGLNS ISVVPVGITKYREGLYELKPFDMESSREVIKQVEAWQMELLSKYGSRIVFIADEFYIM AGLEIPDYCVYEDFPQIENGVGLVAMLKKEFDDYFEELELKLENKREVSIATGVSSYK YIKEMIDILENKYKNLYVHVYKIKNNFFGENVTVTGLLTGQDIERQLSGKNLGRELLL SESMLKSGERVFLDDYTVEMLEDKLKTKITIVRNNGKDFIEKVLGIVL" misc_feature complement(65311..66600) /locus_tag="ClothDRAFT_0316" /note="putative FeS-containing Cyanobacterial-specific oxidoreductase; Region: cyano_FeS_chp; TIGR03279" /db_xref="CDD:132322" misc_feature complement(66412..66600) /locus_tag="ClothDRAFT_0316" /note="PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most...; Region: PDZ_metalloprotease; cd00989" /db_xref="CDD:29046" misc_feature complement(65995..66363) /locus_tag="ClothDRAFT_0316" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cl14056" /db_xref="CDD:187212" misc_feature complement(65335..65958) /locus_tag="ClothDRAFT_0316" /note="Protein of unknown function (DUF512); Region: DUF512; pfam04459" /db_xref="CDD:146883" gene complement(66727..66927) /locus_tag="ClothDRAFT_0317" CDS complement(66727..66927) /locus_tag="ClothDRAFT_0317" /inference="protein motif:TFAM:TIGR01031" /note="TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: dal:Dalk_3305 ribosomal protein L32" /codon_start=1 /transl_table=11 /product="ribosomal protein L32" /protein_id="ZP_05428350.1" /db_xref="GI:256003359" /db_xref="InterPro:IPR002677" /translation="MANPKRKWSKARTGKRRSQWKLTVPNLVECPHCHSLKLLHRVCK ECGHYTVRHKGERKSIEVLSVE" misc_feature complement(66781..66927) /locus_tag="ClothDRAFT_0317" /note="Ribosomal L32p protein family; Region: Ribosomal_L32p; cl09115" /db_xref="CDD:186829" gene complement(67030..67533) /locus_tag="ClothDRAFT_0318" CDS complement(67030..67533) /locus_tag="ClothDRAFT_0318" /inference="protein motif:PFAM:PF02620" /note="PFAM: protein of unknown function DUF177; KEGG: gsu:GSU1598 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF177" /protein_id="ZP_05428351.1" /db_xref="GI:256003360" /db_xref="InterPro:IPR003772" /translation="MKIDISDILKHSGASLRLDFSESIKINDFIAEDFDFAKPVTFKG TLVNAGGIIKLDGELWADYRAKCSRCLKDIESKMHIDVKENFVEEGSNKTDEEYYTYH GKFLELEKVMIDNIILNLPAKQVCDEACKGYCPKCGADLNNDECKCVNEDIDPRLEVF KNFFTDN" misc_feature complement(67042..67371) /locus_tag="ClothDRAFT_0318" /note="Uncharacterized ACR, COG1399; Region: DUF177; cl00616" /db_xref="CDD:186109" gene complement(67774..68973) /locus_tag="ClothDRAFT_0319" CDS complement(67774..68973) /locus_tag="ClothDRAFT_0319" /inference="protein motif:TFAM:TIGR00016" /note="TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: hhe:HH1308 acetate kinase" /codon_start=1 /transl_table=11 /product="acetate kinase" /protein_id="ZP_05428352.1" /db_xref="GI:256003361" /db_xref="InterPro:IPR000890" /db_xref="InterPro:IPR004372" /translation="MNILVINTGSSSLKYQLIDMTNESVLAKGVCDRIGLEHSFLKHT KTGGETVVIEKDLYNHKLAIQEVISALTDEKIGVIKSMSEISAVGHRIVHGGEKFKES AIIDEDVMKAIRDCVELAPLHNPSNIIGIEACKQILPDVPMVAVFDTAFHQTMPRHAY IYALPYEIYEKYKLRKYGFHGTSHKYVAHRAAQMLGKPIESLKLITCHLGNGASICAV KGGKSVDTSMGFTPLQGLCMGTRSGNVDPAVITYLMEKEKMNINDINNFLNKKSGVLG ISGVSSDFRDVQDAAEKGDDRAQLALDIFCYGVRKYIGKYIAVLNGVDAVVFTAGIGE NNAYIRREVLKDMDFFGIKIDLDKNEVKGKEADISAPDAKVKTLVIPTNEELEIARET LRLVKNL" misc_feature complement(67777..68973) /locus_tag="ClothDRAFT_0319" /note="Acetokinase family; Region: Acetate_kinase; cl01029" /db_xref="CDD:186303" gene complement(69090..70166) /locus_tag="ClothDRAFT_0320" CDS complement(69090..70166) /locus_tag="ClothDRAFT_0320" /inference="protein motif:TFAM:TIGR00651" /note="TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: hhe:HH1309 phosphotransacetylase" /codon_start=1 /transl_table=11 /product="phosphate acetyltransferase" /protein_id="ZP_05428353.1" /db_xref="GI:256003362" /db_xref="InterPro:IPR002505" /db_xref="InterPro:IPR004614" /translation="MIIYSYKYYKYSFYDNSFGIMKGEEFMSFLEQIIERAKSDVKTI VLPESTDLRVIKAASMIVKKGIAKVVLIGNEKEIKSLAGDIDLEGVMIEDSLNSEKLE DYANTLYELRKSKGMTIEAARETIKDPLYYGVMMVKKGEADGMVAGAVNSTANTLRPA LQILKTAPGTKLVSSFFVMVVPNCEYGHNGTFVYADCGLVENPDADQLSEIAISASKS FEMLVGAKPQVAMLSYSSYGSAKSELTEKVIKATQLAKEKAPHLAIDGELQVDAAIVP EVAKSKAKGSSVAGKANVLIFPDLDAGNIAYKLTQRLAKAEAYGPITQGLARPVNDLS RGCSAEDIVGVAAITAVQAQYVKA" misc_feature complement(69105..70088) /locus_tag="ClothDRAFT_0320" /note="Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl00390" /db_xref="CDD:185961" gene complement(70357..71181) /locus_tag="ClothDRAFT_0321" CDS complement(70357..71181) /locus_tag="ClothDRAFT_0321" /inference="protein motif:PFAM:PF07719" /note="PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: TPR Domain containing protein" /codon_start=1 /transl_table=11 /product="Tetratricopeptide TPR_2 repeat protein" /protein_id="ZP_05428354.1" /db_xref="GI:256003363" /db_xref="InterPro:IPR001440" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR013105" /translation="MEKNTPVKYAICMVLIILAFLVHKTAGYLLFLAFLIYILYSQRS IFYQVLATRAYKKGDMDRASGWLEKACSAAKGRPSVKILYGYLLLKTGKLEEAEKVFE ELLNSNIDNAGLLQAKSNYALVLWKKGQLKDGIKMLEDVFSNYKNTTIYGSLGYLLIL DGDMNKALNFNKEAYEYNSSDPVILDNLGYTYYKIGNIKKAEEIYRKLIGLNPNFPEA YYNYSCVLKDLGMTESALEMAKKAKNYRLSYLSNLKEEELDNYLEELQSLIATKSE" misc_feature complement(70528..71034) /locus_tag="ClothDRAFT_0321" /note="type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521" /db_xref="CDD:131573" misc_feature complement(70450..70734) /locus_tag="ClothDRAFT_0321" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature complement(order(70495..70500,70507..70512,70519..70524, 70600..70605,70612..70617,70621..70626,70711..70716, 70723..70728,70732..70734)) /locus_tag="ClothDRAFT_0321" /note="binding surface" /db_xref="CDD:29151" misc_feature complement(order(70456..70458,70465..70467,70477..70479, 70513..70515,70558..70560,70567..70569,70579..70581, 70615..70617,70660..70662,70669..70671,70681..70683, 70717..70719)) /locus_tag="ClothDRAFT_0321" /note="TPR motif; other site" /db_xref="CDD:29151" gene complement(71241..72674) /locus_tag="ClothDRAFT_0322" CDS complement(71241..72674) /locus_tag="ClothDRAFT_0322" /inference="protein motif:TFAM:TIGR00133" /note="TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB region; GatB/Yqey domain protein; GatB central domain protein; KEGG: sat:SYN_00309 aspartyl/glutamyl-tRNA amidotransferase subunit B" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase, B subunit" /protein_id="ZP_05428355.1" /db_xref="GI:256003364" /db_xref="InterPro:IPR003789" /db_xref="InterPro:IPR004413" /db_xref="InterPro:IPR006075" /db_xref="InterPro:IPR006107" /translation="MEYEIIVGLEVHVELSTKSKIYCSCTTDFGGEPNTHICPVCTGM PGVLPVLNKKVVEYAVKTGLATNCSIAKYSKQDRKNYFYPDLPKAYQISQYDLPLCRD GYIDIEVEGRTKRIGITRIHIEEDAGKLVHDQNETGTLIDYNRCGVPLIEIVTEPDMR SAQEARAFVESLRNILRYIDVSDCKMQEGSLRVDVNLSVRPKGQKEFGTRTEMKNLNS IRSMVRAIESEAKRQIEVIESGGIIVQETRRWDEHKGVSCSMRTKEEAHDYRYFPEPD LMPIVVDEEWKEEIKRSLPELPDARRKRYVNEYGLPGHDAFILTSSKALADFFEEAAG KCNNAKAVSNFILGDVSRILNDKGMEAEDIPFPAEYLAKLVKLVDQGTISTTIAKKVL EIMFEQKKDPQEIVREEGLEVVSDEKALAEVVKKVISNNTKLVEDYKKGKDKVFGFLV GQAMKETKGKANPRLLNKILKEELDKI" misc_feature complement(71253..72674) /locus_tag="ClothDRAFT_0322" /note="aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477" /db_xref="CDD:180111" misc_feature complement(71805..72665) /locus_tag="ClothDRAFT_0322" /note="GatB/GatE catalytic domain; Region: GatB_N; pfam02934" /db_xref="CDD:145865" misc_feature complement(71253..71693) /locus_tag="ClothDRAFT_0322" /note="GatB domain; Region: GatB_Yqey; cl11497" /db_xref="CDD:159498" gene complement(72688..74148) /locus_tag="ClothDRAFT_0323" CDS complement(72688..74148) /locus_tag="ClothDRAFT_0323" /EC_number="3.5.1.4" /inference="protein motif:TFAM:TIGR00132" /note="KEGG: gur:Gura_4324 aspartyl/glutamyl-tRNA amidotransferase subunit A; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, A subunit; PFAM: Amidase" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase, A subunit" /protein_id="ZP_05428356.1" /db_xref="GI:256003365" /db_xref="InterPro:IPR000120" /db_xref="InterPro:IPR004412" /translation="MELYELTVHEMSDFIKNRKVSAVELVQSVLDRINAIDEKIGSYI TVLEEEALEQAKEVQERIDKGEAKSPLAGIPMALKDNICTKNVKTTCASKMLGSFIPP YDATVSKKLYNEGAVLLGKLNMDEFAMGASTENSYFKITRNPWDLERVPGGSSGGSAA AVAAGMAGFALGSDTGGSIRQPASFCGIVGMKPTYGAVSRFGLVAFASSMDQIGPLTK DVTDCAMVLNAITGYDPMDSTSADVKYPDYSKALINDVKGIRIGIPKEYIGDNTNLDV KKAVLDAAKTLKELGAQVAECSLPLTEYAIPAYYIISSAEASSNLARYDGIKYGYRAK EYTDLMDLYVRTRSEGFGVEVKRRILLGTYALSSGYYDQYYKKALQVRTLIKNAFNEV FEKYDVLLGPAAPTTAFKIGEKKEKPLEMYLGDIYTVSVNIAGLPALTIPCGFDGNNL PIGLQLIGKPFDESTLLRVGYTFEQNTEFHKKRAGI" misc_feature complement(72694..74148) /locus_tag="ClothDRAFT_0323" /note="Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154" /db_xref="CDD:30503" misc_feature complement(72727..74106) /locus_tag="ClothDRAFT_0323" /note="GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cl11426" /db_xref="CDD:187035" gene complement(74190..74477) /locus_tag="ClothDRAFT_0324" CDS complement(74190..74477) /locus_tag="ClothDRAFT_0324" /inference="protein motif:TFAM:TIGR00135" /note="TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; KEGG: pca:Pcar_2167 glutamyl-tRNA (Gln) amidotransferase, C subunit, GatC-like" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase, C subunit" /protein_id="ZP_05428357.1" /db_xref="GI:256003366" /db_xref="InterPro:IPR003837" /translation="MKVDKETIEYVANLARLRLSEKEKEKLALDLESIISYVDKLNEL DTSKIIPTDHVIPIKNVFRDDEVRDSYPKDKMLMNAPEKEDGCFKVPKVVE" misc_feature complement(74193..74477) /locus_tag="ClothDRAFT_0324" /note="Glu-tRNAGln amidotransferase C subunit; Region: Glu-tRNAGln; cl00495" /db_xref="CDD:186035" gene complement(74713..75270) /locus_tag="ClothDRAFT_0325" CDS complement(74713..75270) /locus_tag="ClothDRAFT_0325" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428358.1" /db_xref="GI:256003367" /translation="MEDRFLMYLFYGSAIVLILILVFILLVVKRKNKLKKAVNKTSIN YGNVCVFFDEDNNVTVIPYKKDKHGIGRAVENPMFLKAPYKPLELGSLVRSSMAMCSG KIIHSDSQLMSKLKCKSWDEFAKGKRNISIYYKEALGIVLNTTKRKPDGTYSFNFRGY EKVLKKDVSDEELGIVIMSLLERCR" gene complement(75288..75407) /locus_tag="ClothDRAFT_0326" CDS complement(75288..75407) /locus_tag="ClothDRAFT_0326" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428359.1" /db_xref="GI:256003368" /translation="MLRTGIRCNLEGKKSKNTLKKVMVNLLAAIAVKCRTVED" gene complement(75543..77534) /locus_tag="ClothDRAFT_0327" CDS complement(75543..77534) /locus_tag="ClothDRAFT_0327" /EC_number="6.5.1.2" /inference="protein motif:TFAM:TIGR00575" /note="KEGG: gur:Gura_1305 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase OB-fold; SMART: NAD-dependent DNA ligase ; BRCT domain protein; Helix-hairpin-helix DNA-binding class 1" /codon_start=1 /transl_table=11 /product="DNA ligase, NAD-dependent" /protein_id="ZP_05428360.1" /db_xref="GI:256003369" /db_xref="InterPro:IPR001357" /db_xref="InterPro:IPR001679" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR004149" /db_xref="InterPro:IPR004150" /db_xref="InterPro:IPR013839" /db_xref="InterPro:IPR013840" /translation="MDIEKRILELREILNYHSHKYYVEDAPEISDFEYDELYRELEKL EQERPDLITPDSPTQRIGGKPLEGFKKVVHAVQMQSLSDVFSREELLAFDRRVREAVG DDVEYVVEKKIDGLSVSLVYENGVFTRGATRGDGLVGEDVTQNLKTIRTIPLRLKRDL PLLEVRGEVFISKKDFIKINEEQEAAGQQLFANPRNAAAGSLRQLDPKVTSQRKLDIF VFNIQRIEGQSFKTHSETLEFLKELGFKTSPGYKVCKDINAVWEEINRIGEERGEIDF EIDGAVVKVNSLEQREILGSTIKAPRWAVAYKYPAEVKETVVKKITVNVGRTGVLTPI AIFDPVRLAGSTVSRATLHNMDYIKEKDIRIGDTVRIRKAGDIIPEVVDVVFEKRSGN EAEFNMPEQCPVCGADVVREEGEAAYRCTGIECSAQLYRKIVHFASRDAMNIEGLGPA IIEVLLEKGLIKEIADLYYLHKEKETLVNIERMGKKSVENLLASIEKSKQNNIDRLIF GFGIRHIGLRAAQLLSENFESLDALMNASAEDIMAIPEFGEKMAKSVEQFFRQKQNRD TVEKLKAAGVNTVSFGKKKIKDNRFEGKTFVLTGTLPSFTRKEAEEIIKSFGGKTSGS VSKKTDYVLAGEDAGSKLQKAKELGIEIIDEDKFRKMIE" misc_feature complement(75546..77534) /locus_tag="ClothDRAFT_0327" /note="NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956" /db_xref="CDD:181181" misc_feature complement(76602..77522) /locus_tag="ClothDRAFT_0327" /note="NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114" /db_xref="CDD:29013" misc_feature complement(order(76683..76685,76689..76691,76875..76877, 77031..77033,77136..77138,77199..77201,77205..77207, 77292..77294)) /locus_tag="ClothDRAFT_0327" /note="nucleotide binding pocket; other site" /db_xref="CDD:29013" misc_feature complement(order(77190..77195,77199..77201)) /locus_tag="ClothDRAFT_0327" /note="K-X-D-G motif; other site" /db_xref="CDD:29013" misc_feature complement(77199..77201) /locus_tag="ClothDRAFT_0327" /note="catalytic site; other site" /db_xref="CDD:29013" misc_feature complement(76350..76559) /locus_tag="ClothDRAFT_0327" /note="NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120" /db_xref="CDD:145978" misc_feature complement(76254..76334) /locus_tag="ClothDRAFT_0327" /note="NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119" /db_xref="CDD:145977" misc_feature complement(75546..75758) /locus_tag="ClothDRAFT_0327" /note="Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo/...; Region: BRCT; cd00027" /db_xref="CDD:28909" misc_feature complement(order(75675..75677,75681..75683,75690..75692, 75699..75701,75711..75713)) /locus_tag="ClothDRAFT_0327" /note="Dimer interface; other site" /db_xref="CDD:28909" misc_feature complement(order(75552..75554,75564..75566)) /locus_tag="ClothDRAFT_0327" /note="BRCT sequence motif; other site" /db_xref="CDD:28909" gene complement(77641..78336) /locus_tag="ClothDRAFT_0328" CDS complement(77641..78336) /locus_tag="ClothDRAFT_0328" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: mxa:MXAN_2497 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428361.1" /db_xref="GI:256003370" /translation="MKTIGKYLAILIAVVLLWNQVILKPFRVLSMLFHKMGHAVVAFL FGYGSNAFEAAFGSMGDSMVGAQGWFPSFMISSGGYLGSILFFALIMFLKKTNAKKYL LGSLAIIYLFISISVPALRGTVLYAAVFTAIAILLYMIQRGGVEEIAIDVVAMSSVAY IIYETLVDTVLFKINQQFSIIKGWNTGIPLDMARLKNITGLPELLWAVVWIVIAVLVI NAVVLKMGGTGKR" gene complement(78571..79419) /locus_tag="ClothDRAFT_0329" CDS complement(78571..79419) /locus_tag="ClothDRAFT_0329" /inference="protein motif:PFAM:PF01520" /note="PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; KEGG: cff:CFF8240_1209 N-acetylmuramoyl-L-alanine amidase" /codon_start=1 /transl_table=11 /product="cell wall hydrolase/autolysin" /protein_id="ZP_05428362.1" /db_xref="GI:256003371" /db_xref="InterPro:IPR002508" /translation="MNKKSVVKKMQKRYLHIPPAKRIILLVMGILILTVVGIGIGSKI VSKGSGRGNDYLTDNSNEVVNAGDTDGTSHAGEIKPKEVIVVIDPGHGGEDWGAYSGT LYEKDINLDISLKLGKLLEDLGVKVVYTRETDVFVDLDPRVELANRLDATLFISVHSN SLPDNSEYKGTETLYCPSSNPRYSKMDGKKLATIVQKELINALGTVDNGIIERPNLVV LRKTVMPAVIAEIAYISNPSDRAKLADDAFRQKAAQALANAVMKALDEMGMVKDENGN YMIIPN" sig_peptide complement(79306..79419) /locus_tag="ClothDRAFT_0329" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.671) with cleavage site probability 0.394 at residue 38" misc_feature complement(78640..79170) /locus_tag="ClothDRAFT_0329" /note="N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696" /db_xref="CDD:119407" misc_feature complement(order(78730..78732,78946..78948,79105..79107, 79147..79149)) /locus_tag="ClothDRAFT_0329" /note="active site" /db_xref="CDD:119407" misc_feature complement(order(78946..78948,79105..79107,79147..79149)) /locus_tag="ClothDRAFT_0329" /note="metal-binding site" /db_xref="CDD:119407" gene complement(79647..80636) /locus_tag="ClothDRAFT_0330" CDS complement(79647..80636) /locus_tag="ClothDRAFT_0330" /EC_number="3.4.24.78" /inference="protein motif:TFAM:TIGR01441" /note="TIGRFAM: spore protease; PFAM: peptidase M63 germination protease" /codon_start=1 /transl_table=11 /product="spore protease" /protein_id="ZP_05428363.1" /db_xref="GI:256003372" /db_xref="InterPro:IPR005080" /translation="MERNIRTDLVLEAHELLKENEFKNERREPPGVDVENDGTEDIRI TRVRVTSPTGEAAIGKPMGNYITLEVPRLKENDQELYEETCKALAKELTRVLNLKDDS TILVIGLGNWNVTPDALGPKVVSRLMVTRHLLEYVPDQVDEGVRPVCAVSPGVLGITG IETGEIVRGIVDRVKPDVVIAIDALASRKMERVNTTIQIADTGISPGSGVGNKRMELS RETLGVPVIAIGVPTVVDAATMANDTIDLVIDNLIREAKEDSHFYNMLKNIDRNEKYQ LIQEVLQPYVGNLVVTPKEIDDVVDRIAKVIANGLNIALHQGITLNDVNRYVQ" misc_feature complement(79674..80627) /locus_tag="ClothDRAFT_0330" /note="Germination protease; Region: Peptidase_A25; cl04057" /db_xref="CDD:186613" gene 80871..81140 /locus_tag="ClothDRAFT_0331" CDS 80871..81140 /locus_tag="ClothDRAFT_0331" /inference="protein motif:TFAM:TIGR00029" /note="TIGRFAM: ribosomal protein S20; PFAM: ribosomal protein S20; KEGG: glo:Glov_2108 30S ribosomal protein S20" /codon_start=1 /transl_table=11 /product="ribosomal protein S20" /protein_id="ZP_05428364.1" /db_xref="GI:256003373" /db_xref="InterPro:IPR002583" /translation="MPNIKSAIKRVRISKKKTLQNSMRKSILKTNIKKCKQAIANNEP NAVEALKLAIKTIDKAAAKNIIHKNTAARKKSKLVKALNTALKQQ" misc_feature 80871..81131 /locus_tag="ClothDRAFT_0331" /note="Ribosomal protein S20; Region: Ribosomal_S20p; cl00384" /db_xref="CDD:185957" gene complement(81226..82236) /locus_tag="ClothDRAFT_0332" CDS complement(81226..82236) /locus_tag="ClothDRAFT_0332" /inference="protein motif:TFAM:TIGR01128" /note="TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: gur:Gura_3132 DNA polymerase III, delta subunit" /codon_start=1 /transl_table=11 /product="DNA polymerase III, delta subunit" /protein_id="ZP_05428365.1" /db_xref="GI:256003374" /db_xref="InterPro:IPR005790" /db_xref="InterPro:IPR010372" /translation="MSIDKLKLEVKNKSLGKLYLFYGEEEYLKKFYLGKIEEIILSRD QTGLNKIVIEGKAEASKIIEACETMPFFAEKKLVVVKKSELFNSKKSGSSNNKNDELI TYLQNIPEHTCLVFYEENIDNRLKITSAVKKYGMVVEFPFQKPAELVKWAIKVFKSYG KAIDENTASYLIDTCEEGMTEILNEINKVVLYLGESQKVTVDSIKKVCTKSIKSRIFD LIDAIAERKLDLALKLLNDMIILKEPMPKILFMIAKQLKQLLELKLLCSKGMDAKEAC SKMGINPYAAKKMVRQTDCFSLEKLKEAIRQALELDLSIKTGQINDRTAVEILICSLA AE" misc_feature complement(81232..82236) /locus_tag="ClothDRAFT_0332" /note="DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574" /db_xref="CDD:180139" misc_feature complement(81664..82182) /locus_tag="ClothDRAFT_0332" /note="DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144" /db_xref="CDD:148006" gene 82464..82540 /locus_tag="ClothDRAFT_R0007" /note="tRNA-Met2" tRNA 82464..82540 /locus_tag="ClothDRAFT_R0007" /product="tRNA-Met" gene 82555..82630 /locus_tag="ClothDRAFT_R0008" /note="tRNA-Phe2" tRNA 82555..82630 /locus_tag="ClothDRAFT_R0008" /product="tRNA-Phe" gene 82684..82769 /locus_tag="ClothDRAFT_R0009" /note="tRNA-Tyr1" tRNA 82684..82769 /locus_tag="ClothDRAFT_R0009" /product="tRNA-Tyr" gene complement(82842..84146) /locus_tag="ClothDRAFT_0333" CDS complement(82842..84146) /locus_tag="ClothDRAFT_0333" /inference="protein motif:TFAM:TIGR01087" /note="TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: gur:Gura_3976 UDP-N-acetylmuramoylalanine--D-glutamate ligase" /codon_start=1 /transl_table=11 /product="UDP-N-acetylmuramoylalanine/D-glutamate ligase" /protein_id="ZP_05428366.1" /db_xref="GI:256003375" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR005762" /db_xref="InterPro:IPR013221" /translation="MYRLGADITAFDKADEVKLKSTLEQFKGMDIKYSLGEGYLDNLK GFDILFRTPGMRYDIPEILAAKEEGTEVTSEMEVFFELCPAEIFAVTGSDGKTTTTTL IYNMLKEQGYKCWLGGNIGIPLLSKIEEIKDTDKVVLELSSFQLHTMTKSPNVAVVTN VSPNHLDVHKSMEEYVSAKKNIFRYQSAEDRLVLNFDNDITREFAGEAKGDVVYFSRK TVLEKGAMLKDDMLVFRDGETETEIAKASDIVIPGVHNVENFLAATAAVIDCVDRDVI RKVATTFTGVEHRIELVREINGVKFYNDSIASSPTRTIAGLNSFKDKVILIAGGYDKK IPYDALGPVIAEKVKCLVLIGQTAPKIEKALRDETERSGKGSDIPIKKCTSLEEAVKV AYRFASVGDVVILSPASASFDMFKNFEERGNRFKEIVNSIEA" misc_feature complement(82851..84146) /locus_tag="ClothDRAFT_0333" /note="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01710" /db_xref="CDD:179323" misc_feature complement(83346..83879) /locus_tag="ClothDRAFT_0333" /note="Mur ligase middle domain; Region: Mur_ligase_M; pfam08245" /db_xref="CDD:149357" misc_feature complement(83061..83291) /locus_tag="ClothDRAFT_0333" /note="Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875" /db_xref="CDD:145824" gene complement(84388..84927) /locus_tag="ClothDRAFT_0334" CDS complement(84388..84927) /locus_tag="ClothDRAFT_0334" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428367.1" /db_xref="GI:256003376" /translation="MRSVSLTNDRGLKRILDIMERCSEKVDVKIMSIVLYGARAKGDK TSQSVYEFLVLSNNDTPLDKFILFNETVKLELLSEKYLNVNILNYTPEIFEEILYKDE MVGTFLYMICRENIILYDRYGTFMSIKERMLNSKIKSEEIFLRQCIEFSKKIGSEKWV RKFDKTLMHYMYRNNRKRL" gene 85257..85343 /locus_tag="ClothDRAFT_R0010" /note="tRNA-Leu4" tRNA 85257..85343 /locus_tag="ClothDRAFT_R0010" /product="tRNA-Leu" gene 85483..85725 /locus_tag="ClothDRAFT_0335" CDS 85483..85725 /locus_tag="ClothDRAFT_0335" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428368.1" /db_xref="GI:256003377" /translation="MLTFKFEFDVLKSREELNIKTITVTNRKETIFTGENSLYKLTHE DLRSLIFKVAEKINERKTLKSGDIDKIFEVLNTVFE" gene 85787..86116 /locus_tag="ClothDRAFT_0336" CDS 85787..86116 /locus_tag="ClothDRAFT_0336" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428369.1" /db_xref="GI:256003378" /translation="MTLQERIEKFEKEGWKYEPEFRLHTRGNTIIQFMALTKDGYYRK IQSGKIGPAKKYTSDEDIEFMKNSWGGAREGAGRKPTGRKKKVYYVTDEEDVQIREYL QKLRNKQ" gene 86308..86634 /locus_tag="ClothDRAFT_0337" CDS 86308..86634 /locus_tag="ClothDRAFT_0337" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428370.1" /db_xref="GI:256003379" /translation="MAKRYLIYQEFYFADMVRDGWMEYISPEVAALCPTGIGGWFSFL REDENGKTIDEILDDWKNNYDFVKYILKIKRFPINDREEVIRISYVDEHDELCECIYV LEKETV" gene complement(86997..88337) /locus_tag="ClothDRAFT_0338" CDS complement(86997..88337) /locus_tag="ClothDRAFT_0338" /inference="protein motif:PFAM:PF01547" /note="PFAM: extracellular solute-binding protein family 1; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="extracellular solute-binding protein family 1" /protein_id="ZP_05428371.1" /db_xref="GI:256003380" /db_xref="InterPro:IPR006059" /translation="MKNTAVKLLLVFPVLLAYIFFTGCSKKPAKAEENTQIQISSTPQ QDFDLGGYTVRIAQWWDASPNDRSSIARHKAAEEKYNCKIEYITITWDQIVSKFTSSV LSGEPIADIVLFEMTRALPVLAESDLIIPVDDYFDFNDRKWPPIIRQIGRYKGKQYGF TNYCWTVTGIFYNKVLFDRLGLPDPYMLQENGDWTWEKFAEIAQMATRDEDGDGENDL WGLVIQGHNLYSPLILSNNANIINFDENGRAIYALDDPNAIEALQFFEDLHNKYKVVA PVEDPTDWYEAPRKFSEGNIAMFFGHGWDGQELKNTMKDDFGFVFFPKGPKASDYIVP VQQECKIYVMPKYAKHPREVAKVFEEISPFYNDNVGFESWINTFLDTDGEKNTARMML EKGKVSLHQAYPTFDNLLFNKIAREIIIDNISVEDFAKNFKDEAQKAIDSEYER" misc_feature complement(87015..88181) /locus_tag="ClothDRAFT_0338" /note="ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653" /db_xref="CDD:31839" misc_feature complement(87261..88109) /locus_tag="ClothDRAFT_0338" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398" /db_xref="CDD:187020" gene complement(88623..89168) /locus_tag="ClothDRAFT_0339" CDS complement(88623..89168) /locus_tag="ClothDRAFT_0339" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428372.1" /db_xref="GI:256003381" /translation="MEGLFSEGLYTGGFTEAVCNNALLKSINELDSITNVDDYLKNLE NIVHLIMEEIKQVNSETRHLFGKPGDTTPWILNENIRLKTYKMVQRLADFLPENEDVR IKKETVAQPVNTYIGILKLKLCMTAIQIFATSFKAVLPMKSEYSRFQSSLTYIFNTAL EIDNELGRALDSNRVKNFIQN" gene complement(89412..90947) /locus_tag="ClothDRAFT_0340" CDS complement(89412..90947) /locus_tag="ClothDRAFT_0340" /inference="protein motif:PFAM:PF01694" /note="PFAM: Rhomboid family protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="Rhomboid family protein" /protein_id="ZP_05428373.1" /db_xref="GI:256003382" /db_xref="InterPro:IPR002610" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR013105" /translation="MIIKALSRLLIERGNYFPVIDENGNVVIDDNRAMLHRYGPEGYV VAEIVSGDLLTPEQIKTGLEMVRSRQEQIKERFNTYYFKVFVFSSDLPEDKLEILASE NYNEGINGNYLCCISVNVEKKEFAKYYEYPRISYGIHNQIQYFFSNDFDSDYGNVDFK ELAKKNEKGYKIEIKDKKPWVTYVLIAVNILVWLLIEIYARSKGVDSSSLLVDFGAKE NTHIMMGEYWRFVTPMFLHNGITHLVVNSYSLYVLGTTVEMIMGKGRFLFIYLMAGLM GSIVSFIFSIAPSVGASGAIFGLLGALIYYGTEHRELFKKGFGRGILTTLLINIVYGL SVPRIDNFGHFGGLLGGFLASGVVGLPSFRRSLKKKTVFMVAAAVILSTSLYYGFTNT QNQSLKKLELMSGFLNERNWVESEKLGEEIIKMHPKNEAILFNALWNLAMSEAKQGKY DEAVEHAQMLTEVDPANGHFLLGIIYNDAGNVEMSKKELEEAVKIDPRLRNKVESILN TIK" misc_feature complement(89925..90275) /locus_tag="ClothDRAFT_0340" /note="Rhomboid family; Region: Rhomboid; cl11446" /db_xref="CDD:187043" misc_feature complement(89457..89732) /locus_tag="ClothDRAFT_0340" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature complement(order(89472..89474,89481..89483,89493..89495, 89529..89531,89568..89570,89577..89579,89589..89591, 89625..89627,89682..89684,89691..89693,89703..89705)) /locus_tag="ClothDRAFT_0340" /note="TPR motif; other site" /db_xref="CDD:29151" misc_feature complement(order(89511..89516,89523..89528,89535..89540, 89610..89615,89622..89627,89631..89636)) /locus_tag="ClothDRAFT_0340" /note="binding surface" /db_xref="CDD:29151" gene complement(90984..91604) /locus_tag="ClothDRAFT_0341" CDS complement(90984..91604) /locus_tag="ClothDRAFT_0341" /inference="protein motif:PFAM:PF02631" /note="PFAM: regulatory protein RecX; KEGG: mmw:Mmwyl1_3631 regulatory protein RecX" /codon_start=1 /transl_table=11 /product="regulatory protein RecX" /protein_id="ZP_05428374.1" /db_xref="GI:256003383" /db_xref="InterPro:IPR003783" /translation="MMITSVEKDTKNRGMLSVFIDEKYAFSIPEEDYFRLCLYDKKEL SSDEIEEIKKGVSQRTAKYKAVKYLSYRYMTEAELSQKLRKDGYDEDVILNVVTELKS MGYINDLIYAQKYVYDRIKLKPKAKKMLKRELNQKGVSDEIADQVLSELDFDEDVVIE RLIRKKFGKYDMKDPKIQKRIYSFLLHRGFDFENIKRVLRTITHLD" misc_feature complement(91005..91427) /locus_tag="ClothDRAFT_0341" /note="RecX family; Region: RecX; cl00936" /db_xref="CDD:186270" gene complement(92018..93067) /locus_tag="ClothDRAFT_0342" CDS complement(92018..93067) /locus_tag="ClothDRAFT_0342" /inference="protein motif:TFAM:TIGR02012" /note="KEGG: glo:Glov_3161 recombinase A; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="recA protein" /protein_id="ZP_05428375.1" /db_xref="GI:256003384" /db_xref="InterPro:IPR001553" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013765" /translation="MIEKKKALEMVLGQIEKQFGKGAVMKLGENTHMNIETIPTGALG LDIALGVGGVPRGRIVEIFGPESSGKTTVALHIIAEAQKAGGEAAFIDAEHALDPVYA KNLGVDIENLIVSQPDTGEQALEIAEALVRSGAIDVIVIDSVAALVPKAEIDGEMGDS HVGLQARLMSQALRKLAGVINKSRTTAIFINQLREKVGVMFGNPETTPGGRALKFYAS VRLDVRRLESIKQGNEVIGSRTKVKVVKNKVAPPFKEAEFDIIYGQGISKEGNILDVA VNLDIVNKSGAWFSYNGQKIGQGRENAKQFLKENPEIAKEIETKIRENYNQTFLMSIN AQVDTDDEVDLEDEE" misc_feature complement(92090..93061) /locus_tag="ClothDRAFT_0342" /note="RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983" /db_xref="CDD:29984" misc_feature complement(92090..93061) /locus_tag="ClothDRAFT_0342" /note="recombinase A; Provisional; Region: recA; PRK09354" /db_xref="CDD:181793" misc_feature complement(order(92141..92143,92279..92281,92423..92425, 92435..92437,92738..92743,92756..92776,92780..92785, 92990..93004,93014..93016,93023..93028,93032..93037)) /locus_tag="ClothDRAFT_0342" /note="hexamer interface; other site" /db_xref="CDD:29984" misc_feature complement(92855..92878) /locus_tag="ClothDRAFT_0342" /note="Walker A motif; other site" /db_xref="CDD:29984" misc_feature complement(order(92279..92290,92354..92356,92393..92395, 92492..92494,92642..92644,92765..92767,92774..92776, 92786..92788,92852..92872)) /locus_tag="ClothDRAFT_0342" /note="ATP binding site; other site" /db_xref="CDD:29984" misc_feature complement(92642..92656) /locus_tag="ClothDRAFT_0342" /note="Walker B motif; other site" /db_xref="CDD:29984" gene complement(93168..94745) /locus_tag="ClothDRAFT_0343" CDS complement(93168..94745) /locus_tag="ClothDRAFT_0343" /inference="protein motif:TFAM:TIGR01695" /note="TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; multi antimicrobial extrusion protein MatE; KEGG: sat:SYN_00104 virulence factor protein" /codon_start=1 /transl_table=11 /product="integral membrane protein MviN" /protein_id="ZP_05428376.1" /db_xref="GI:256003385" /db_xref="InterPro:IPR002528" /db_xref="InterPro:IPR004268" /translation="MGKNKKLTGAALIVMSSIIVSRITGFVREMLVPNLIGVNEEGDA YTVAFKITGLMYDMLVGGAVSAALIPVLSGYIARDDEETGWKVVGTFINTVIVAMVAV CFLGIIFAPQVVSLIGAGFETDAQKQLTVDLIRILFPSVAFLMMAGLCNGVLNSYNRF AAAAYGPSLYNIGSALSIIVFSVSRWGVRGVAFGVMLSSLVYFLFQLSFAVKNLKLYR FKFYLKHEGSKKLFKLAIPSLISSAIVQINAVISSTFATLFGVGGATALNIGDRTWQL PYGVFAQGMGIAMLPSLSSNIAKGEVDEYKNTLIKGIKTVLFFTIPSGVGFIVLKEPV IRTIFKFTSRFDEGAVSVAANVLMFFSIALLSQSIVTVTNRAFYAINDTLTPLLVGGS TIIINILLSIVFYKMTNLGVAGMALAYSLASAVNAFLLLSILNRKMKGIYIDRLLRFL FKVVPSAMIMGMVLFITNACFVPDTSAKVVQLLNLIFQIALGVLVYFAAVLVLKVEEA LYFKDMALSRLKKIVKK" sig_peptide complement(94680..94745) /locus_tag="ClothDRAFT_0343" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.752) with cleavage site probability 0.594 at residue 22" misc_feature complement(93222..94730) /locus_tag="ClothDRAFT_0343" /note="integral membrane protein MviN; Region: mviN; TIGR01695" /db_xref="CDD:162493" misc_feature complement(93537..94037) /locus_tag="ClothDRAFT_0343" /note="MatE; Region: MatE; pfam01554" /db_xref="CDD:144956" gene complement(94790..96031) /locus_tag="ClothDRAFT_0344" CDS complement(94790..96031) /locus_tag="ClothDRAFT_0344" /inference="protein motif:TFAM:TIGR00200" /note="TIGRFAM: competence/damage-inducible protein CinA; molybdenum cofactor synthesis domain protein; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: dds:Ddes_1466 competence/damage-inducible protein CinA" /codon_start=1 /transl_table=11 /product="competence/damage-inducible protein CinA" /protein_id="ZP_05428377.1" /db_xref="GI:256003386" /db_xref="InterPro:IPR001453" /db_xref="InterPro:IPR008135" /db_xref="InterPro:IPR008136" /translation="MNAEILAVGTELLMGQIANTNAQYISKRLNDIGVNVYYHSVVGD NSVRLKKCLLAALERCDLVIMTGGLGPTQDDLTKETVAEVLGKKLVLHEESLERIKTF FTRINRKMTDNNVKQAYLPEGCTVVENNSGTAPGCIIEDKGKIVVMLPGPPPEMMPML DDTVIPYLAEKSGYRIVSKYLRVFGIGESQLEEMIMDLVDKQDRVTIATYAKDGQVTV RLTTKARTEEEGFREILPLQNEIASRLKEALYSTEDEELEYVAAKILIDNNITIATAE SCTGGLISARLTDVPGISKVFNRGIVSYSNEAKMENLGVKPETLEKYGAVSSRTAMEM AEGVRKIASTDIGLAVTGIAGPDGGTDEKPVGLVYVALAHSLGTEVRELRLAGNRNRI RNLTVLNAFDMVRRYVMKLKG" misc_feature complement(94799..96031) /locus_tag="ClothDRAFT_0344" /note="competence damage-inducible protein A; Provisional; Region: PRK00549" /db_xref="CDD:179060" misc_feature complement(95519..96028) /locus_tag="ClothDRAFT_0344" /note="Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885" /db_xref="CDD:58166" misc_feature complement(order(95558..95560,95567..95569,95579..95584, 95822..95830)) /locus_tag="ClothDRAFT_0344" /note="putative MPT binding site; other site" /db_xref="CDD:58166" misc_feature complement(94808..95272) /locus_tag="ClothDRAFT_0344" /note="Competence-damaged protein; Region: CinA; cl00666" /db_xref="CDD:186135" gene 96268..97221 /locus_tag="ClothDRAFT_0345" CDS 96268..97221 /locus_tag="ClothDRAFT_0345" /inference="protein motif:TFAM:TIGR01771" /note="TIGRFAM: L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; KEGG: L-lactate dehydrogenase (predicted); K00016 L-lactate dehydrogenase" /codon_start=1 /transl_table=11 /product="L-lactate dehydrogenase" /protein_id="ZP_05428378.1" /db_xref="GI:256003387" /db_xref="InterPro:IPR001236" /db_xref="InterPro:IPR001557" /db_xref="InterPro:IPR001732" /db_xref="InterPro:IPR011304" /translation="MNNNKVIKKVTVVGAGFVGSTTAYTLMLSGLISEIVLIDINAKK ADGEVMDLNHGMPFVRPVEIYRGDYKDCAGSDIVIITAGANQKEGETRIDLVKRNTEV FKNIINEIVKYNNDCILLVVTNPVDILTYVTYKLSGFPKNKVIGSGTVLDTARFRYLL SEHVKVDARNVHAYIIGEHGDTEVAAWSLANIAGIPMDRYCDECHQCEEQISRNKIYE SVKNAAYEIIRNKGATYYAVALAVRRIVEAIVRNENSILTVSSLLEGQYGLSDVCLSV PTIVGVNGIEEILNVPFNDEEIQLLRKSGNTLKEIIKTLDI" sig_peptide 96268..96345 /locus_tag="ClothDRAFT_0345" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.916) with cleavage site probability 0.465 at residue 26" misc_feature 96307..97212 /locus_tag="ClothDRAFT_0345" /note="A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292" /db_xref="CDD:133428" misc_feature 96307..97212 /locus_tag="ClothDRAFT_0345" /note="L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066" /db_xref="CDD:178836" misc_feature order(96313..96321,96382..96387,96397..96399,96514..96516, 96562..96564,96637..96639,96964..96969) /locus_tag="ClothDRAFT_0345" /note="NAD binding site; other site" /db_xref="CDD:133428" misc_feature order(96325..96330,96337..96339,96352..96354,96409..96411, 96415..96420,96427..96432,96934..96936,96943..96948, 96958..96960,96970..96978,96985..96987) /locus_tag="ClothDRAFT_0345" /note="dimer interface; other site" /db_xref="CDD:133428" misc_feature order(96637..96639,96802..96804,96937..96939,96949..96951) /locus_tag="ClothDRAFT_0345" /note="substrate binding site; other site" /db_xref="CDD:133428" misc_feature order(96766..96768,96775..96777,96781..96783,96787..96789, 96838..96840,96844..96849,97024..97029,97033..97035, 97123..97128,97132..97134) /locus_tag="ClothDRAFT_0345" /note="tetramer (dimer of dimers) interface; other site" /db_xref="CDD:133428" gene 97343..98299 /locus_tag="ClothDRAFT_0346" CDS 97343..98299 /locus_tag="ClothDRAFT_0346" /inference="protein motif:PFAM:PF07726" /note="PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: gur:Gura_0187 ATPase" /codon_start=1 /transl_table=11 /product="ATPase associated with various cellular activities AAA_3" /protein_id="ZP_05428379.1" /db_xref="GI:256003388" /db_xref="InterPro:IPR011703" /db_xref="InterPro:IPR011704" /translation="MNNSVEILNKIVSNIEKVIVGKKKAIELILISLICDGHVLIEDV PGVGKTSIVSSLAKSVNASFKRIQFTPDILPSDITGFTMYNQKEGKFEYHPGSIMSQI ILADEINRTSPKTQASLLEAMEEKQVTVDGVTYNLPRPFMVLATQNPVEYLGTYPLPE AQLDRFFMKVSIGYPEKFEESEILSRFHDENPLETLKPVADSSDILNIQSEVKKVYVD RSINNYIVDIVSRTRFHSEISLGSSPRGSLSLYRASQAWALYNERNFVIPEDVKLMSI PVLSHRIILKQEARLKKISPEEIIDTIIKSVNVPAVDKYAKK" misc_feature 97358..98272 /locus_tag="ClothDRAFT_0346" /note="MoxR-like ATPases [General function prediction only]; Region: COG0714" /db_xref="CDD:31058" misc_feature 97400..97864 /locus_tag="ClothDRAFT_0346" /note="The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes...; Region: AAA; cd00009" /db_xref="CDD:99707" misc_feature 97469..97492 /locus_tag="ClothDRAFT_0346" /note="Walker A motif; other site" /db_xref="CDD:99707" misc_feature order(97472..97495,97658..97660,97784..97786) /locus_tag="ClothDRAFT_0346" /note="ATP binding site; other site" /db_xref="CDD:99707" misc_feature 97646..97663 /locus_tag="ClothDRAFT_0346" /note="Walker B motif; other site" /db_xref="CDD:99707" misc_feature <97829..98248 /locus_tag="ClothDRAFT_0346" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature 97835..97837 /locus_tag="ClothDRAFT_0346" /note="arginine finger; other site" /db_xref="CDD:99707" gene 98286..99494 /locus_tag="ClothDRAFT_0347" CDS 98286..99494 /locus_tag="ClothDRAFT_0347" /inference="protein motif:PFAM:PF01882" /note="PFAM: protein of unknown function DUF58; KEGG: gur:Gura_0188 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF58" /protein_id="ZP_05428380.1" /db_xref="GI:256003389" /db_xref="InterPro:IPR002881" /translation="MQRNRILYSFLYVLSLIFIYFYGGKIPYMLFYTVLLLPFVSIAI TSIAFVRFKYVQDIDKRSVVKGEEINYTLSIHNEDFFLYPYIKINFFNNDTIFSNQFE PQCFSLLPFKKKTFSYKLCCKYRGDFFVGVKSIEFEDYLGIVKFVHEPISIKEITVYP RLIKLDSLKLKTDYLSESHALSNSRFENTLTFSDVRKYTYGDSMKKIHWKLSSKMNEL LVKNFEGSSHASSAILLDLKKSNRSFEENSIIEDMLIEASIAVIYYCLVNWIPINFIY YNSKGFNTIEAKNALEFKEIYEILSGIKFENTMDIKDVLNIYVKNSVLKKTSILLFTS NLDYGLYDEIYKTKLMGYDINLVYVCPKHVVNTASFEVNNILNELLEIGVMVYKIQTE DDIKNVLEYR" misc_feature 98286..>99083 /locus_tag="ClothDRAFT_0347" /note="Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721" /db_xref="CDD:31907" misc_feature 98859..99107 /locus_tag="ClothDRAFT_0347" /note="Protein of unknown function DUF58; Region: DUF58; pfam01882" /db_xref="CDD:145184" gene 99528..102200 /locus_tag="ClothDRAFT_0348" CDS 99528..102200 /locus_tag="ClothDRAFT_0348" /inference="protein motif:PFAM:PF01841" /note="PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: scl:sce8271 hypothetical protein" /codon_start=1 /transl_table=11 /product="transglutaminase domain protein" /protein_id="ZP_05428381.1" /db_xref="GI:256003390" /db_xref="InterPro:IPR002931" /translation="MDGKKILDYLAGFVLAALMSFSLVYPLTTTLGFPYSSFRILGLV IFILFIYSVLFANRNVSRISVPLAIISMAAGIVFLAVKKDLAYIIQPFQWFTKYIYDE AILPDNYYPLFITVILALSLTLLVFIFTMKKFNFIIILSSGTAIFVSQWILNFFVPSA YISFYTFVISILAYYLVHIYRKKSLENSNNDFASPSKFILGIAPICVVIVFLANSIPV RSKPIEWKWLDNKINSFYNQLGFGTLGKGSAGFDSDYFSFYSTAGFGNDSNLGGNITP NDIKIMEVTTDRSIYLRGRACNLYTGNSWLNSQPDNIPLDGTNKMSFDILEMKTGLPL LVNKLNPENNTYKLSDTDGIIPNIISKHNVKVKYENVRTKSLFVPLKSENFIFPSKVA DAVLINQDGILTSNKFLKKDFTYSFESYSLNTVSEDFKNLLRQSMRGLYSVELNRLTD EIYEHLYSEYLKDLLDEAERIYNSDLFILNRYSVQFPIKNIIRNTPDNITLSDLLYEY LVNVFIDEFNLDRVFEREDLEGYFQMIINELNNSEDIKKLAQLRSLSSNSVYIYNTYL NIPSELPQRVKDLAVSITANETNNFDRAKAIEKYLSANYGYTLTPGDTPPDRDFVDYF LFEQKEGYCVYFASAMVILARSIGLPARYVEGFVLPVRSKDGVYEVTNKQAHAWPEIY FEGFGWVSFEPTPVYQQNSFYSSGSFRPNMSGMLPQTNGTGLQNQNNDEGNKPDMAPQ PVQNQNPFINILLITAGILAGLVSFVLIIVGINKIRKKHWLKSILNMSPKEAVIKLYE TYLNHLLYQYMPVRPAETPLEYAKRLDDYGYFAPRKFTDVASIFVKARYSQNEVTEAD RASALEFYKPIVLKTRSSMGRLKYFFLAHILGKI" sig_peptide 99528..99602 /locus_tag="ClothDRAFT_0348" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.731) with cleavage site probability 0.706 at residue 25" misc_feature 101256..101606 /locus_tag="ClothDRAFT_0348" /note="Transglutaminase-like superfamily; Region: Transglut_core; cl10469" /db_xref="CDD:176834" gene complement(102336..102530) /locus_tag="ClothDRAFT_0349" CDS complement(102336..102530) /locus_tag="ClothDRAFT_0349" /inference="protein motif:PFAM:PF04024" /note="PFAM: PspC domain protein; KEGG: cbc:CbuK_0644 stress-responsive transcriptional regulator" /codon_start=1 /transl_table=11 /product="phage shock protein C, PspC" /protein_id="ZP_05428382.1" /db_xref="GI:256003391" /db_xref="InterPro:IPR007168" /translation="MKKLYLSNSDKIIGGVCGGVAEYFEIDPTLIRLIAVIATVLTGF VGGIIIYIVAMIIIPKRPFF" misc_feature complement(<102399..102530) /locus_tag="ClothDRAFT_0349" /note="PspC domain; Region: PspC; cl00864" /db_xref="CDD:186227" gene complement(102666..103904) /locus_tag="ClothDRAFT_0350" CDS complement(102666..103904) /locus_tag="ClothDRAFT_0350" /EC_number="2.1.2.1" /inference="protein motif:PRIAM:2.1.2.1" /note="PFAM: glycine hydroxymethyltransferase; Orn/Lys/Arg decarboxylase major region; KEGG: gur:Gura_1881 serine hydroxymethyltransferase" /codon_start=1 /transl_table=11 /product="Glycine hydroxymethyltransferase" /protein_id="ZP_05428383.1" /db_xref="GI:256003392" /db_xref="InterPro:IPR000310" /db_xref="InterPro:IPR001085" /translation="MFNLNEISKIDPEVAKAIELEVNRQRNKIELIASENFVSKAVIE AMGTPLTNKYAEGYPGKRYYGGCEFVDIIENLAIERAKKIFGAEHANVQPHSGAQANM AVFFAVLNPGDTILGMNLSHGGHLSHGSPVNMSGKYYNVISYGVRKEDCRIDYDEVRK LAKEHRPKLIVAGASAYPRIIDFKAFRDIADEVGAYLMVDIAHIAGLVAAGLHPNPVP YAHFVTTTTHKTLRGPRGGLILCGNEHAKMIDKAVFPGIQGGPLMHVIAAKAVSFAEV LTDEFKQYQQQIVKNAKTLANALMEKGIDLVSGGTDNHLMLVDLRNKGLTGKYVQHIL DEVCITVNKNGIPFDPESPFVTSGIRIGTPAVTARGMKEEDMVEIADLINLTITDYEN SKEKVKERVRMLCEKYPLYQ" misc_feature complement(102693..103880) /locus_tag="ClothDRAFT_0350" /note="Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of...; Region: SHMT; cd00378" /db_xref="CDD:99733" misc_feature complement(order(103065..103067,103119..103121, 103491..103496,103599..103601,103620..103622, 103665..103667,103689..103694,103746..103748, 103800..103802,103815..103817,103842..103847, 103866..103868,103872..103874)) /locus_tag="ClothDRAFT_0350" /note="dimer interface; other site" /db_xref="CDD:99733" misc_feature complement(order(102825..102827,103200..103202, 103218..103223,103296..103298,103305..103307, 103380..103382,103530..103532,103611..103616, 103713..103715,103743..103745,103803..103805)) /locus_tag="ClothDRAFT_0350" /note="glycine-pyridoxal phosphate binding site; other site" /db_xref="CDD:99733" misc_feature complement(order(102825..102827,103218..103220, 103530..103532,103803..103805)) /locus_tag="ClothDRAFT_0350" /note="active site" /db_xref="CDD:99733" misc_feature complement(order(102873..102875,103143..103145, 103527..103529,103533..103535,103545..103547, 103716..103718,103737..103739)) /locus_tag="ClothDRAFT_0350" /note="folate binding site; other site" /db_xref="CDD:99733" gene complement(104337..105320) /locus_tag="ClothDRAFT_0351" CDS complement(104337..105320) /locus_tag="ClothDRAFT_0351" /inference="protein motif:PFAM:PF02769" /note="PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: aeh:Mlg_2063 AIR synthase-like protein" /codon_start=1 /transl_table=11 /product="AIR synthase related protein domain protein" /protein_id="ZP_05428384.1" /db_xref="GI:256003393" /db_xref="InterPro:IPR000728" /db_xref="InterPro:IPR010918" /translation="MDIGKVPNSVLTELIINKIKANRKEILIRPKVGEDCCAVDFGKD VCVLSSDPITGAVNEVGRLAVHVSCNDVASCGAEPLGLLMTILAPEGTKEKDIENVMT QIVDTANSLNVDIIGGHTEITTAVNRIVIISTAVGKVLKDKLVTTSGAKPGDDIIVTK AAGIEGTAIIAHDKEKELVDIIGKEAVERAKTFINYVSVLKEGIIAGTFGVNSMHDVT EGGILGAVWEVTEASETGAVIYKSKVPVKDETQKICKVYGIDPLRLISSGCMIITCKN GRELVKELENNGIEAAVIGKITADLGRKLVCEDNQVIDISEPGSDELYKVV" misc_feature complement(104340..105320) /locus_tag="ClothDRAFT_0351" /note="Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypE; COG0309" /db_xref="CDD:30657" misc_feature complement(104430..105317) /locus_tag="ClothDRAFT_0351" /note="AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like1; cd06061" /db_xref="CDD:100037" misc_feature complement(order(104637..104639,104913..104915, 104925..104930,104964..104966,105060..105062, 105069..105071,105078..105080,105108..105110, 105165..105167,105171..105173,105177..105188)) /locus_tag="ClothDRAFT_0351" /note="dimerization interface; other site" /db_xref="CDD:100037" misc_feature complement(order(104964..104972,105108..105110)) /locus_tag="ClothDRAFT_0351" /note="putative ATP binding site; other site" /db_xref="CDD:100037" gene complement(105462..106148) /locus_tag="ClothDRAFT_0352" CDS complement(105462..106148) /locus_tag="ClothDRAFT_0352" /inference="protein motif:COG:COG1655" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428385.1" /db_xref="GI:256003394" /translation="MLDSLYNKSVVCPVCQNKIEVTKVKSKDCVVASRDSDFCVYYES VNPLFYEVWVCEHCGYAALQERFENISPIEAKIVKENISKYWKPRSFCGERDVDKAIE AFKLALYNLCKISPKPIEYAKVCLRIAWLYRMKKDEQQEIKFLNHALRYYRETYENEP FPVGKLDEHTCVYMIGELSRRVGNYDDAIFWFNKIISSPGARENKALIDSTREQYHLA KEAKEAKEKA" misc_feature complement(105531..106148) /locus_tag="ClothDRAFT_0352" /note="Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655" /db_xref="CDD:31841" misc_feature complement(105498..106136) /locus_tag="ClothDRAFT_0352" /note="Uncharacterized protein conserved in bacteria (DUF2225); Region: DUF2225; pfam09986" /db_xref="CDD:150637" gene complement(106166..107590) /locus_tag="ClothDRAFT_0353" CDS complement(106166..107590) /locus_tag="ClothDRAFT_0353" /inference="protein motif:PFAM:PF04294" /note="PFAM: VanW family protein; G5 domain protein; KEGG: scl:sce5267 vancomycin resistance gene" /codon_start=1 /transl_table=11 /product="VanW family protein" /protein_id="ZP_05428386.1" /db_xref="GI:256003395" /db_xref="InterPro:IPR007391" /db_xref="InterPro:IPR011098" /translation="MLLDFFSKNKTKILIFAASLLLLVIASVSTYVVVVLNRKTFYDG IAVEGIDVSGLTVDEAREKVEKKLDRIVYENSLLLNYEGMTWRIGLSDISYDFLVDDA IKRAYSIGREGSVLKRLKTIRNLKSDKKNVLAKVVFSRPLLEEYITSIKKQVDENPKD ATVTYQNGNIMFEKEIIGRFVDVDKNLGLLENKLIKRDFSPFELEVTNVYPKIMYKDI SHIEEVISSFSTVFNSANVNRSHNIKLACERINNTVLLPGETFSMDASLGSRTKENGY KDAPVIVKGRLIEGVGGGVCQVTSTLYVAVLKAKLEVVERVKHSMPLGYVEPGQDATI SEGYIDFKFRNNTDRACLISASVVGNRIDIKLLGAKRNSNYDVRLKSVVVERISPPED EIIVDKSLPKGAVKIEREPVQGLKVIVYRETYENNRLIEREKISEDIYKPVQGLKRVG PYDSNDTEGGEETVKEEAMEEQTI" sig_peptide complement(107492..107590) /locus_tag="ClothDRAFT_0353" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.502 at residue 33" misc_feature complement(107003..107311) /locus_tag="ClothDRAFT_0353" /note="Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229" /db_xref="CDD:152664" misc_feature complement(106487..106879) /locus_tag="ClothDRAFT_0353" /note="VanW like protein; Region: VanW; pfam04294" /db_xref="CDD:146762" misc_feature complement(106238..106462) /locus_tag="ClothDRAFT_0353" /note="G5 domain; Region: G5; pfam07501" /db_xref="CDD:148868" gene complement(107711..108889) /locus_tag="ClothDRAFT_0354" CDS complement(107711..108889) /locus_tag="ClothDRAFT_0354" /inference="protein motif:TFAM:TIGR00342" /note="TIGRFAM: thiamine biosynthesis/tRNA modification protein ThiI; PFAM: thiamine biosynthesis protein; THUMP domain protein; ExsB family protein; KEGG: cbd:CBUD_1272 thiamine biosynthesis protein" /codon_start=1 /transl_table=11 /product="thiamine biosynthesis/tRNA modification protein ThiI" /protein_id="ZP_05428387.1" /db_xref="GI:256003396" /db_xref="InterPro:IPR003720" /db_xref="InterPro:IPR004114" /db_xref="InterPro:IPR004479" /translation="MKKVILVRYGEILLKGLNRPIFEDKLMSNIKRAIHKLGKVRITK SQARIYIEPLEENYDFDEALKLLSKVFGIVSVSTVWKIDSDFECIKENSVKMVKDLIN REGYKTFKVETKRGNKRFPMDSPEISRQLGGYILRNVPELSVDVKNPDFILYVEVREF TYIYSEIIQAVCGMPLGSNGKAVLLLSGGIDSPVAGWMIAKRGVEIEAVHFYSYPYTS ERAKEKVIELTKILATYCQKINLHIVPFTEIQLEINEKCPHEELTIIMRRAMMRIAEI IANKTGALALVTGESVGQVASQTIQSLVVTNAVVSLPVFRPLIGMDKNEVVDIAKKIG TFETSILPYEDCCTVFVAKHPTTKPKLERIQLSESRLNMEELINKAVENTEVLTITRD " misc_feature complement(107720..108889) /locus_tag="ClothDRAFT_0354" /note="thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565" /db_xref="CDD:179303" misc_feature complement(108407..108649) /locus_tag="ClothDRAFT_0354" /note="THUMP domain; Region: THUMP; cl12076" /db_xref="CDD:159736" misc_feature complement(107819..108349) /locus_tag="ClothDRAFT_0354" /note="ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712" /db_xref="CDD:30167" misc_feature complement(order(108251..108253,108257..108259, 108314..108325,108329..108337)) /locus_tag="ClothDRAFT_0354" /note="Ligand Binding Site; other site" /db_xref="CDD:30167" gene complement(108886..110049) /locus_tag="ClothDRAFT_0355" CDS complement(108886..110049) /locus_tag="ClothDRAFT_0355" /EC_number="2.8.1.7" /inference="protein motif:PRIAM:2.8.1.7" /note="PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cbc:CbuK_1045 cysteine desulfhydrase" /codon_start=1 /transl_table=11 /product="Cysteine desulfurase" /protein_id="ZP_05428388.1" /db_xref="GI:256003397" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR001597" /translation="MSREIYLDNSATTRPYDEVIDFVNHISREVYGNPSSLHTKGIEA ERMVRNAREIVAKSLGVSRDEIYFTSGGTEANNLAIAGYLFANPRKGKHIITTKIEHP SVLEVFNNLSQHGYKVDFIDVDKNGIVIVDDLRKKINEETSLISVIYINNETGAVQPI DKIVEVKNSINKDIVLHVDAVQAYGKIRIAPEKQGIDLLTMSSHKIHGPKGVGALYTR RDIKLKPIIFGGGQESQLRSGTENVPGICGFGAAVDITFRKMEESSKYCEKLKSMLLD MLKKEVEDVVIVSPEGSSPYILNAAFPNVRAEVLLHHLETKNIFVSTGAACSSRKQVL SHVLRAMGIKPEIIEGAIRFSFSSFNNEEDIIKTVEAIKDILPKIRIKRGGRR" misc_feature complement(108922..110037) /locus_tag="ClothDRAFT_0355" /note="Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520" /db_xref="CDD:30866" misc_feature complement(108934..110037) /locus_tag="ClothDRAFT_0355" /note="Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321" /db_xref="CDD:185903" misc_feature complement(order(109435..109437,109444..109446, 109504..109506,109513..109515,109603..109605, 109822..109824,109831..109836)) /locus_tag="ClothDRAFT_0355" /note="pyridoxal 5'-phosphate binding pocket; other site" /db_xref="CDD:99742" misc_feature complement(109435..109437) /locus_tag="ClothDRAFT_0355" /note="catalytic residue; other site" /db_xref="CDD:99742" gene complement(110325..110987) /locus_tag="ClothDRAFT_0356" CDS complement(110325..110987) /locus_tag="ClothDRAFT_0356" /inference="protein motif:PFAM:PF07238" /note="PFAM: type IV pilus assembly PilZ; KEGG: wri:WRi_001450 hypothetical protein" /codon_start=1 /transl_table=11 /product="type IV pilus assembly PilZ" /protein_id="ZP_05428389.1" /db_xref="GI:256003398" /db_xref="InterPro:IPR009875" /translation="MARYNLDGGTGLFNALGNRNPAKVVKLGSGVDIKHFKMFEYINA EVLGKTDDSIKVEAKDVLKETLFFPGDHVVVNYSNTQDLFVMDGNINHVYDINPLIID VKINKVEKLKDLRKHERFYVSLMANIRVCGTSKLVFAVVKNMSSGGIKINCNEQLTTE DVLEVEILLDRTNKLVFSGAVVRKNKVNDYYEYGIEIRGISENNLKCLYHYLKWLDSD YR" misc_feature complement(110352..110651) /locus_tag="ClothDRAFT_0356" /note="PilZ domain; Region: PilZ; cl01260" /db_xref="CDD:163963" gene complement(111527..112282) /locus_tag="ClothDRAFT_0357" CDS complement(111527..112282) /locus_tag="ClothDRAFT_0357" /inference="protein motif:TFAM:TIGR00613" /note="TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O RecO; KEGG: sat:SYN_01535 DNA repair protein" /codon_start=1 /transl_table=11 /product="DNA repair protein RecO" /protein_id="ZP_05428390.1" /db_xref="GI:256003399" /db_xref="InterPro:IPR003717" /translation="MNYLKTSGIVIKEVNTGEADRIITIFSKNKGKISALAKGARRPK SHLVAGTQLLCYSEFVLFKGKDMYTVNSCDVIESFYDIRNDLERLTYAAHMMDIVNDV ILENQPASRLLQLFLNSLYMLSKTDRSPLQIVRVFEIRLLSTMGYAPWVSSCIKCGST VFDSMYFSFLKCGFLCSKCLENDKGALKISEGAAKALNYIVHSKMSNLFSFEVSESVL DELGKVSQRYMKERLEKNYTKLDFIKTLDRIKC" misc_feature complement(112046..112282) /locus_tag="ClothDRAFT_0357" /note="Recombination protein O N terminal; Region: RecO_N; pfam11967" /db_xref="CDD:152402" misc_feature complement(111545..112273) /locus_tag="ClothDRAFT_0357" /note="DNA repair protein RecO; Region: reco; TIGR00613" /db_xref="CDD:161959" misc_feature complement(111578..112036) /locus_tag="ClothDRAFT_0357" /note="Recombination protein O C terminal; Region: RecO_C; pfam02565" /db_xref="CDD:145610" gene complement(112298..112441) /locus_tag="ClothDRAFT_0358" CDS complement(112298..112441) /locus_tag="ClothDRAFT_0358" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428391.1" /db_xref="GI:256003400" /translation="MLKEFAWKAFENTGDITTYMFFKEIEEKTKAARENEITRDEVAT THH" gene complement(112590..113483) /locus_tag="ClothDRAFT_0359" CDS complement(112590..113483) /locus_tag="ClothDRAFT_0359" /inference="protein motif:TFAM:TIGR00436" /note="TIGRFAM: GTP-binding protein Era; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; KEGG: gme:Gmet_2315 GTP-binding protein Era" /codon_start=1 /transl_table=11 /product="GTP-binding protein Era" /protein_id="ZP_05428392.1" /db_xref="GI:256003401" /db_xref="InterPro:IPR001547" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR004044" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR005662" /db_xref="InterPro:IPR006073" /translation="MAFKSGFVSIVGRPNVGKSTLLNKFTGEKIAIMSDKPQTTRNTI RAIDTGEDYQIIYIDTPGIHKPKTKLGDFMVNIALDSLNEVDLVLFLVEATCPQPGPG DLYIIEQLKNLKTPVFCLINKIDLVEKEQILPIIAAYKDTMEFSQIIPISALEYESVE VVKNEIKKVLPEGPKYFPDDMITDQPEKVIAAELIREKILHLLSDEVPHGVGVEVVTF KKRDDKDILDIQATIYCEKESHKGILIGKEGKMLKKIGSLSRAEIEGLFGTKVFLELW VKVKPDWRNNEFMLKTLGYKK" misc_feature complement(112599..113483) /locus_tag="ClothDRAFT_0359" /note="GTPase Era; Reviewed; Region: era; PRK00089" /db_xref="CDD:178854" misc_feature complement(112974..113477) /locus_tag="ClothDRAFT_0359" /note="Era subfamily. Era (E. coli Ras-like protein) is a multifunctional GTPase found in all bacteria except some eubacteria. It binds to the 16S ribosomal RNA (rRNA) of the 30S subunit and appears to play a role in the assembly of the 30S subunit...; Region: Era; cd04163" /db_xref="CDD:133363" misc_feature complement(113427..113450) /locus_tag="ClothDRAFT_0359" /note="G1 box; other site" /db_xref="CDD:133363" misc_feature complement(order(113025..113030,113109..113111, 113115..113120,113298..113300,113364..113372, 113382..113384,113424..113444)) /locus_tag="ClothDRAFT_0359" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133363" misc_feature complement(order(113355..113399,113403..113405)) /locus_tag="ClothDRAFT_0359" /note="Switch I region; other site" /db_xref="CDD:133363" misc_feature complement(113364..113366) /locus_tag="ClothDRAFT_0359" /note="G2 box; other site" /db_xref="CDD:133363" misc_feature complement(order(113232..113237,113295..113312)) /locus_tag="ClothDRAFT_0359" /note="Switch II region; other site" /db_xref="CDD:133363" misc_feature complement(113298..113309) /locus_tag="ClothDRAFT_0359" /note="G3 box; other site" /db_xref="CDD:133363" misc_feature complement(113109..113120) /locus_tag="ClothDRAFT_0359" /note="G4 box; other site" /db_xref="CDD:133363" misc_feature complement(113022..113030) /locus_tag="ClothDRAFT_0359" /note="G5 box; other site" /db_xref="CDD:133363" misc_feature complement(112599..112793) /locus_tag="ClothDRAFT_0359" /note="K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains...; Region: KH-I; cl00098" /db_xref="CDD:153510" gene complement(113539..113925) /locus_tag="ClothDRAFT_0360" CDS complement(113539..113925) /locus_tag="ClothDRAFT_0360" /inference="protein motif:TFAM:TIGR01354" /note="TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; KEGG: similar to cytidine deaminase ; K01489 cytidine deaminase" /codon_start=1 /transl_table=11 /product="cytidine deaminase" /protein_id="ZP_05428393.1" /db_xref="GI:256003402" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR006262" /db_xref="InterPro:IPR016192" /translation="MDDRKLLAMAEDIKKNSYSPYSKFRVGAAVLAKSGKVFTGVNIE NASFGATVCAERTAVFKAVSEGEREIAAVAISSDSDEYTFPCGICRQVLREFGDDDTK VICGNKNGEFTVFRLGELLPNAFFKF" misc_feature complement(113572..113907) /locus_tag="ClothDRAFT_0360" /note="Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283" /db_xref="CDD:29826" misc_feature complement(order(113659..113661,113668..113670, 113761..113769,113794..113796,113800..113802, 113848..113850,113854..113856)) /locus_tag="ClothDRAFT_0360" /note="active site" /db_xref="CDD:29826" misc_feature complement(order(113659..113661,113668..113673, 113761..113769)) /locus_tag="ClothDRAFT_0360" /note="catalytic motif; other site" /db_xref="CDD:29826" misc_feature complement(order(113659..113661,113668..113670, 113761..113763,113767..113769)) /locus_tag="ClothDRAFT_0360" /note="Zn binding site; other site" /db_xref="CDD:29826" gene complement(114141..114629) /locus_tag="ClothDRAFT_0361" CDS complement(114141..114629) /locus_tag="ClothDRAFT_0361" /inference="protein motif:PFAM:PF02130" /note="PFAM: protein of unknown function UPF0054; KEGG: sun:SUN_1265 putative metalloprotease" /codon_start=1 /transl_table=11 /product="protein of unknown function UPF0054" /protein_id="ZP_05428394.1" /db_xref="GI:256003403" /db_xref="InterPro:IPR002036" /translation="MEIFIENIQDKIEITDEILELMEKAIKMCLEHEKFEYPYEVSII LTDNEKIREINYEQRNIDKPTDVLSFPIVDMYDGVIKSSQGDFDLDEGRIILGDILIS MEKAKEQSMEYGHSFERELIFLLTHGVFHLLGYDHDTPEREKKMFEKQEAILKSLNLE RN" misc_feature complement(114147..114626) /locus_tag="ClothDRAFT_0361" /note="Uncharacterized protein family UPF0054; Region: UPF0054; cl00402" /db_xref="CDD:185971" gene complement(114730..116931) /locus_tag="ClothDRAFT_0362" CDS complement(114730..116931) /locus_tag="ClothDRAFT_0362" /inference="protein motif:TFAM:TIGR00277" /note="KEGG: pca:Pcar_1232 HD superfamily hydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase 7TM intracellular region; metal-dependent phosphohydrolase 7TM extracellular region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region" /codon_start=1 /transl_table=11 /product="7TM receptor with intracellular metal dependent phosphohydrolase" /protein_id="ZP_05428395.1" /db_xref="GI:256003404" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /db_xref="InterPro:IPR011621" /db_xref="InterPro:IPR011624" /translation="MTKDKDRSNNGSKKAFYKNKRIQRLFIAAAAIVLAFLIVLNGAT PRKYRVTLGAISEYDIISPRDIVNTVKTEENARKAASQVSPVMRDIPNAPIEVINLVD KLFFLINDAQNTYKSKISSITGSRRYEELASNALSETKAAFVESIGELGIKLEDAQID YLISNAGEEDINSLEVVIRSKVNDIMRKDITEDNLEERKNELKDAIFNSEIKYELKNV GLTVSDFVLKPNRTIDEELTKARRDAAYNDPRNIETIKKGQKILSAGDIVTEDKLQVL EDLNLLETTSRFDFAFAGGILAIILFLSLLLILYMHNFCKKVYYNRTDLILLSVVILM ILFIARWVHEYSPLIIPIFIATMLISILLDLRLAIMVNVVLTVAISLMINNDFKFIYM ALVTGTFSAFIVSKANKRNRLSLAGIIVSAINVLLVAAINIMYKTGWEILLKECALVF ANGIMSMVITIGLLPFLESTFNVITPLRLLELANPNQPLLKRLLMEAPGTYHHSLMVG NLAEAATEAIGGNALLARVGAYFHDIGKLKRPNFFMENQMSGNPHDDMTANLSALVIT SHIHDGNEMAKKYKIPLPIRDIILQHHGTTLVKYFYHKAKTTEKLENVEEENFRYDGV KPTTKEAAVVMLADSVEAAVRSMPDKTEAKIEELIRKIIKDKLDDGQLDNCSLTLKDL DSIAKAFMKVFSGVFHSREEYPDIKKKEDSVEDVNNENEQKDQNPKTESLE" sig_peptide complement(116803..116931) /locus_tag="ClothDRAFT_0362" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.760 at residue 43" misc_feature complement(114805..116799) /locus_tag="ClothDRAFT_0362" /note="Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480" /db_xref="CDD:31669" misc_feature complement(116080..116784) /locus_tag="ClothDRAFT_0362" /note="7TM-HD extracellular; Region: 7TMR-HDED; pfam07697" /db_xref="CDD:148996" misc_feature complement(115507..116004) /locus_tag="ClothDRAFT_0362" /note="7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698" /db_xref="CDD:148997" misc_feature complement(114943..115440) /locus_tag="ClothDRAFT_0362" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077" /db_xref="CDD:28958" misc_feature complement(order(115018..115020,115333..115338, 115423..115425)) /locus_tag="ClothDRAFT_0362" /note="Zn2+ binding site; other site" /db_xref="CDD:28958" misc_feature complement(115333..115335) /locus_tag="ClothDRAFT_0362" /note="Mg2+ binding site; other site" /db_xref="CDD:28958" gene complement(116975..117976) /locus_tag="ClothDRAFT_0363" CDS complement(116975..117976) /locus_tag="ClothDRAFT_0363" /inference="protein motif:PFAM:PF02562" /note="PFAM: PhoH family protein; KEGG: dal:Dalk_3324 PhoH family protein" /codon_start=1 /transl_table=11 /product="PhoH family protein" /protein_id="ZP_05428396.1" /db_xref="GI:256003405" /db_xref="InterPro:IPR003714" /translation="MESLVEVSLEFDRIEHAMNLFGNFDENINIIEDAFNVKIISRDN EIRVVGYSDAVYKAQTVLQRLIAMAAQGDIISKQNVSYFVQLAEENQLDKIKGFTADF VCLTARGRQIKAKTHGQKVYVDAIKENDIVFGIGPAGTGKTFLAVAMAVNAFRNKEVN RIVLTRPAVEAGEKLGFLPGDLQNKVDPYLRPLYDALYEMMGAETYHKYLEKGMIEVA PLAYMRGRTLDDSFIILDEAQNTTPEQMKMFLTRIGFGSKAVITGDITQIDLPGEKKS GLVEVMKVLKDVKGISFVHLSDMDVVRHELVQRIIQAYERYDREKKEKGKKESKETN" misc_feature complement(117020..117964) /locus_tag="ClothDRAFT_0363" /note="Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702" /db_xref="CDD:31888" misc_feature complement(117032..117643) /locus_tag="ClothDRAFT_0363" /note="PhoH-like protein; Region: PhoH; cl12134" /db_xref="CDD:187188" gene complement(117977..119173) /locus_tag="ClothDRAFT_0364" CDS complement(117977..119173) /locus_tag="ClothDRAFT_0364" /inference="protein motif:TFAM:TIGR02876" /note="TIGRFAM: sporulation protein YqfD; PFAM: putative stage IV sporulation YqfD" /codon_start=1 /transl_table=11 /product="sporulation protein YqfD" /protein_id="ZP_05428397.1" /db_xref="GI:256003406" /db_xref="InterPro:IPR010690" /translation="MLIFRLWNYIRGYVIIFVEGYFLEKFVNICTRRQILLWDIQRDR NSKMTLKVSIRGFKMLKPVAKKTGCRVKILEKRGLPFLLNRYRHRKTFLLGAAVFVVL FYIMTSFVWSVEVVGNKKIETDGILKCLEKYGVKPGVLKYRINPEEVANGVILDIDGL SYVNVLVRGTKVKVEVAEGVKRPSIIPLNVPCDIVAKKDGVIKSVIVKIGQAQVKEGD TVKKGQLLVSGSIPIKGAEDNPKRVHAMAEVLARTWYEGRQPVELKAVEKIRTGRKKD NVTLVLFSKKINLFHKEIDFKDFEKVEIKKNLSIGEEFVLPFGLVIERYYENDLVEAD ISLEDAKENAAGIAYRKAAENIPEGATIVDKRVNFIENENGEIIADVIIECLEDIGVA KENGGE" misc_feature complement(118001..119158) /locus_tag="ClothDRAFT_0364" /note="sporulation protein YqfD; Region: spore_yqfD; TIGR02876" /db_xref="CDD:163055" misc_feature complement(118004..119158) /locus_tag="ClothDRAFT_0364" /note="Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898" /db_xref="CDD:148491" gene complement(119189..119506) /locus_tag="ClothDRAFT_0365" CDS complement(119189..119506) /locus_tag="ClothDRAFT_0365" /inference="protein motif:TFAM:TIGR02856" /note="TIGRFAM: sporulation protein YqfC; PFAM: protein of unknown function DUF1429" /codon_start=1 /transl_table=11 /product="sporulation protein YqfC" /protein_id="ZP_05428398.1" /db_xref="GI:256003407" /db_xref="InterPro:IPR009877" /translation="MPGKRKKSAKKRKEEEQKINLKEKMAELLELPKEIVLDLPKITM FGNKNLIVENYKGIIEYDNSRIRVNTGKGIIRVTGEGLIIKEITSEDLMIDGEILSLE FLK" misc_feature complement(119195..119446) /locus_tag="ClothDRAFT_0365" /note="YabP family; Region: YabP; cl06766" /db_xref="CDD:164089" gene complement(119602..120564) /locus_tag="ClothDRAFT_0366" CDS complement(119602..120564) /locus_tag="ClothDRAFT_0366" /inference="protein motif:TFAM:TIGR02884" /note="TIGRFAM: delta-lactam-biosynthetic de-N-acetylase; PFAM: polysaccharide deacetylase; KEGG: swd:Swoo_4312 polysaccharide deacetylase" /codon_start=1 /transl_table=11 /product="delta-lactam-biosynthetic de-N-acetylase" /protein_id="ZP_05428399.1" /db_xref="GI:256003408" /db_xref="InterPro:IPR002509" /db_xref="InterPro:IPR014235" /translation="MIKRRVIRGAIVLTIMLALLLSIRFLATREQENLKLPDMGGVFS VRLENLDFTTEITGMLSDGVIDEVPYEEYEDVFAEVEAIPVSGGYSNKVLRWGILRKG YGETPQADPGAPELLAKYGGVYLGDTSKKVIYLTFDEGYENGYTSKILDVLRDNNVKA VFFITGPYLNEHEDLVRRMVEEGHVVGNHTVHHPSLPSLSDKELEEEILGLDRAFHEK FGINMKFLRPPKGEYSERTLAITQKLGYTNLFWSFAYDDWHRDKIRGPQYAYDKVMNN LHNGAVLLLHAVSKDNADALDMIIKGARERGFEFGDVNDLILEK" sig_peptide complement(120478..120564) /locus_tag="ClothDRAFT_0366" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.918) with cleavage site probability 0.505 at residue 29" misc_feature complement(119617..120279) /locus_tag="ClothDRAFT_0366" /note="Polysaccharide deacetylase; Region: Polysacc_deac_1; cl12061" /db_xref="CDD:164326" gene complement(120797..121498) /locus_tag="ClothDRAFT_0367" CDS complement(120797..121498) /locus_tag="ClothDRAFT_0367" /inference="protein motif:PFAM:PF05949" /note="PFAM: protein of unknown function DUF881" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF881" /protein_id="ZP_05428400.1" /db_xref="GI:256003409" /db_xref="InterPro:IPR010273" /translation="MKFSRNISITIICIILGIMLSWQYKSIESNKRVSASQTKNLYDL QKELLEEKKNNENLRARNEELEKQLAQYIDAAGNNKQIEESIKEQLTRARMLAGLVDV QGPGVEIVLDDGEYDYQKVYDIDLLKLVNELRAAEAQAISINGERIVAMTEIRYADPY MVINGRQIFPPYVVKAIADPEKLDYALNMLGGVVEIFRDSFGYKISVTKVDKITIPKV RDDGSVLKYNLLTPL" misc_feature complement(120800..121240) /locus_tag="ClothDRAFT_0367" /note="Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949" /db_xref="CDD:147869" gene complement(121498..122211) /locus_tag="ClothDRAFT_0368" CDS complement(121498..122211) /locus_tag="ClothDRAFT_0368" /inference="protein motif:PFAM:PF05949" /note="PFAM: protein of unknown function DUF881" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF881" /protein_id="ZP_05428401.1" /db_xref="GI:256003410" /db_xref="InterPro:IPR010273" /translation="MKKNDKSYILALLFLVFGILLSVQFRSVLNSKKNKPSIAYQIEN LQNEIKTEKLKGSKLREEIDQNIKKQDEYIKMFMERKNDDEFAREWEKAKLVAGLTDV VGNGVIVYLADAPQQYGGKLEYYVVHDVEIMEVLNELKKAGAQAISVNNERIISTSEI ICLGPTVRINRNRYPVPYEIKAIGDPKKLYEALVNSPIAGEFQMFNKKFEVRMAKDIV IPKYGGDIDDLVSGLEVVE" sig_peptide complement(122143..122211) /locus_tag="ClothDRAFT_0368" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.893) with cleavage site probability 0.363 at residue 23" misc_feature complement(121531..121950) /locus_tag="ClothDRAFT_0368" /note="Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949" /db_xref="CDD:147869" gene 122441..123070 /locus_tag="ClothDRAFT_0369" CDS 122441..123070 /locus_tag="ClothDRAFT_0369" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428402.1" /db_xref="GI:256003411" /translation="MLWSLLMPKLVFRDISVSFDNVLDVAKASSGGQRDVNFLKFLVD SKLLVQEEAILARTITDFKEETYMQKYKKMRDESTRHYLCRAILTEELDKLGIDVVPG TDVGNMNILRANANYDIAAKDLSFIMDIGFTPARNFFRGLTDTRVKYYLVTTYFDDYM DDIIFCCLKRADDEAFLDAVKDYEDGFKMFIPEDSLSAGTENFDTDTLP" gene 123207..123524 /locus_tag="ClothDRAFT_0370" CDS 123207..123524 /locus_tag="ClothDRAFT_0370" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428403.1" /db_xref="GI:256003412" /translation="MFYQIRYQTGEIEDMVAEMKKGNIPCMDVDNMDEFNWVVKKLEE YNIYLAKNIPFDKNARDRVKEPEFEFRAAFSSSKDSEDNLMYIDFYFEPYVEKDYDPI FGD" gene complement(123584..126046) /locus_tag="ClothDRAFT_0371" CDS complement(123584..126046) /locus_tag="ClothDRAFT_0371" /inference="protein motif:PFAM:PF00483" /note="PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; KEGG: geo:Geob_1007 nucleotidyl transferase" /codon_start=1 /transl_table=11 /product="Nucleotidyl transferase" /protein_id="ZP_05428404.1" /db_xref="GI:256003413" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR005844" /translation="MKAVIMAGGEGTRLRPLTCNRPKPMVPVVNKPVMEHIIELLKKH GFTDIAVTLQYLPDMIKDYFGDGSDFGINLRYYVEDKPMGTAGSVKNAEEFLDDTFLV ISGDALTDIDLGKAVEYHYSKGSMATLVLKKVDIPLEYGVVVTDENGRITRFLEKPSW GEVFSDTVNTGIYILSPEVLKYFNKNEMFDFSKDLFPMLLKENKPMYGYITDEYWCDI GDLMAYSKAHMDVLDGKVKINIPGNKIKDRVWVGEGTVIEENVVIEEPCVIGANTRIK KDSVIGSYSVLGDNNIIGERSGIKRSILWKNNVLETNTQLRGTVVCSKVNIKEGVFAF ENSVIGDDTQIGKNAVIKPSIKIWPNKIVEGGTEVNSNLVWGSKFVRSIFGFRGVAGE INVDITPEYASKLGAAYGAIFKGKGKIGVSSDDSAAAKMLKMSFMSGLLSAGLKVLDF GVLHLPVARSAVRFYGADGGIHISTSSTNFGRLTVDFLDKNGSNIKREVERKIENAFQ REDFSRCEGEAIKDVEVIPDYTKYYLRNIINNTRSKDFGYRIALNSLSGFILETVGNL LETFGCTVEKTSLDLRNAKTMRNGNKSAEMTYFTDMIKMGNYDLGVSIEDTSEKMMLV DNNGRIVSDDMFTALISLIVFKTVQGGTVVVPISTSSVVDKLAEQNNGKVIRTKTSPQ DIMNKMLGNETKENVYEQFTLHFDAIAGLVKILDFMKSENYSLSDLVNMIPDFYVSEK EVECSWNVKGKVIRQIIQENEGQSIETLEGVKIFKDGGWVLVLPDAEQPVCRIKSESY SAEFAEELTNFYVNKVREISQK" misc_feature complement(124940..126046) /locus_tag="ClothDRAFT_0371" /note="Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208" /db_xref="CDD:31401" misc_feature complement(125390..126040) /locus_tag="ClothDRAFT_0371" /note="NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181" /db_xref="CDD:133024" misc_feature complement(order(125540..125542,125726..125731, 125735..125737,125810..125812,125975..125980, 126020..126031)) /locus_tag="ClothDRAFT_0371" /note="active site" /db_xref="CDD:133024" misc_feature complement(order(125729..125731,125735..125737, 125891..125893,126023..126031)) /locus_tag="ClothDRAFT_0371" /note="Substrate binding site; other site" /db_xref="CDD:133024" misc_feature complement(order(125390..125392,125396..125398, 125729..125731)) /locus_tag="ClothDRAFT_0371" /note="Mg++ binding site; other site" /db_xref="CDD:133024" misc_feature complement(124940..125326) /locus_tag="ClothDRAFT_0371" /note="Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160" /db_xref="CDD:107413" misc_feature complement(order(124943..124945,124949..124951, 124961..124963,124991..124993,124997..125002, 125015..125017,125078..125080,125084..125086, 125102..125104)) /locus_tag="ClothDRAFT_0371" /note="putative trimer interface; other site" /db_xref="CDD:100038" misc_feature complement(order(124955..124957,124991..124993, 125006..125011,125015..125017)) /locus_tag="ClothDRAFT_0371" /note="putative CoA binding site; other site" /db_xref="CDD:100038" misc_feature complement(123596..124921) /locus_tag="ClothDRAFT_0371" /note="Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109" /db_xref="CDD:31306" misc_feature complement(123605..124900) /locus_tag="ClothDRAFT_0371" /note="GTP-mannose-1-phosphate guanyltransferase (MPG1 transferase), also known as GDP-mannose pyrophosphorylase, is a bifunctional enzyme with both phosphomannose isomerase (PMI) activity and GDP-mannose phosphorylase (GMP) activity. The protein contains an...; Region: MPG1_transferase; cd05805" /db_xref="CDD:100097" gene 126417..126740 /locus_tag="ClothDRAFT_0372" CDS 126417..126740 /locus_tag="ClothDRAFT_0372" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428405.1" /db_xref="GI:256003414" /translation="MPRSTKVNNDYMSNGITIKPAVPTAGENLTVMYDGLLSKSGASH VYAHVGFDRDWKHVYDYPMKRTSIGFEATIPVMEADTLNICFKDCANNWDNNSGANYT FDISK" misc_feature 126534..126725 /locus_tag="ClothDRAFT_0372" /note="Carbohydrate binding domain (family 25); Region: CBM_25; pfam03423" /db_xref="CDD:146190" gene 126950..127417 /locus_tag="ClothDRAFT_0373" CDS 126950..127417 /locus_tag="ClothDRAFT_0373" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: viral A-type inclusion protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428406.1" /db_xref="GI:256003415" /translation="MMFYNRRMYINRYPVPQNQIAANDSEEVQKDSETKRDDNTEDNK KLILDAFKSINDTLMENIKELNRLISKLAERVENLENQIFALESQIESEKSGRNQIPQ SEISNITTELELLKRNSSVIQPEENKEPSNKPIMPGCGFSAITPEYLRSLYKR" misc_feature <126998..>127303 /locus_tag="ClothDRAFT_0373" /note="chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168" /db_xref="CDD:162739" gene 127581..127838 /locus_tag="ClothDRAFT_0374" CDS 127581..127838 /locus_tag="ClothDRAFT_0374" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428407.1" /db_xref="GI:256003416" /translation="MKYQEDFFGTKTELADFVKKVVPELFAGKLTVEGKNVVIPSDRQ VDYKIKYSEDEEGAAVTLKISWDFETATEEEEEEGIELDVE" gene 127953..129002 /locus_tag="ClothDRAFT_0375" CDS 127953..129002 /locus_tag="ClothDRAFT_0375" /inference="protein motif:TFAM:TIGR02906" /note="TIGRFAM: spore coat protein, CotS family; PFAM: aminoglycoside phosphotransferase" /codon_start=1 /transl_table=11 /product="spore coat protein, CotS family" /protein_id="ZP_05428408.1" /db_xref="GI:256003417" /db_xref="InterPro:IPR002575" /db_xref="InterPro:IPR014255" /translation="MPINHEPLFDVLSQYDIKVVSIRNESYKDKKGVWWIQTPDEYKI LKKISNSEDTFKYILSAAEHLRKNGVNIPAVYKTKDGKDYVNINGTCYVLYEAVEGKN PSYNSPEDFRAIVRELAGFHAASVGFSPPDNTKPKIHLGKWVEQYTEQVEDMNRFYQT ELEKSENDRIGKVIIEEFPAFYERAKQAIEGLKGKEYQDWVEKVKSRGGLCHQDFAAG NLLKNPSGKIFVLDTDSITIDIPARDIRKLLNKIMKKNGKWDLEILRKFIRIYQSENP LSFSEWTVVKFDLMFPHLFLGAMNKFYYKRDKEWSFEKYLKRINEMTALEKTITPVLE NFDSIVYEEINQRKD" misc_feature 128049..128798 /locus_tag="ClothDRAFT_0375" /note="Phosphotransferase enzyme family; Region: APH; pfam01636" /db_xref="CDD:145007" misc_feature 128103..>128354 /locus_tag="ClothDRAFT_0375" /note="Protein Kinases, catalytic domain; Region: PKc_like; cl09925" /db_xref="CDD:186871" misc_feature <128277..128774 /locus_tag="ClothDRAFT_0375" /note="Protein Kinases, catalytic domain; Region: PKc_like; cl09925" /db_xref="CDD:186871" gene 129008..130045 /locus_tag="ClothDRAFT_0376" CDS 129008..130045 /locus_tag="ClothDRAFT_0376" /inference="protein motif:TFAM:TIGR02906" /note="TIGRFAM: spore coat protein, CotS family; PFAM: aminoglycoside phosphotransferase; KEGG: pau:PA14_35990 FadE36, aminoglycoside phosphotransferase" /codon_start=1 /transl_table=11 /product="spore coat protein, CotS family" /protein_id="ZP_05428409.1" /db_xref="GI:256003418" /db_xref="InterPro:IPR002575" /db_xref="InterPro:IPR014255" /translation="MNEVGKNPNMDLSKLASSVLEEYGIEPENISVVQSANIKTVWRI KTKDRELCLKRLKHPLDKALFSVNAQDFIYNHGGNVAGIIRDKEGNLIHSFNDQLFVV YEWLYGRDLSFVNADDLKSALHGLAKFHIASKGYVAPEGAKVSSKLGRWPEQYKSMAD KLSSWKEASLGKPASASVNAYLKNVDEMLDICHRAMELLNASKYAELAGENSKSAVLC HQDYGKGNALFTDNGVYVIDLDGVTWDHPGRDLRKIIGKLSENRGAWSLDQIEKILDW YSEINPLSTADRELIYIDLMYPHWFFGLVKNIFKNNKSESPSKIEKTARLETSKVPLL AEKLRDIKSQG" misc_feature 129056..129886 /locus_tag="ClothDRAFT_0376" /note="Protein Kinases, catalytic domain; Region: PKc_like; cl09925" /db_xref="CDD:186871" misc_feature order(129116..129118,129128..129130,129161..129163, 129170..129172,129248..129250,129314..129325, 129668..129670,129680..129685,129689..129691, 129716..129721,129776..129778) /locus_tag="ClothDRAFT_0376" /note="active site" /db_xref="CDD:88612" misc_feature order(129116..129118,129668..129670,129776..129778) /locus_tag="ClothDRAFT_0376" /note="substrate binding site; other site" /db_xref="CDD:88612" misc_feature order(129128..129130,129161..129163,129170..129172, 129248..129250,129314..129325,129668..129670, 129680..129685,129689..129691,129716..129721) /locus_tag="ClothDRAFT_0376" /note="ATP binding site; other site" /db_xref="CDD:88612" gene 130062..131354 /locus_tag="ClothDRAFT_0377" CDS 130062..131354 /locus_tag="ClothDRAFT_0377" /inference="protein motif:PFAM:PF00534" /note="PFAM: glycosyl transferase group 1; KEGG: eck:EC55989_4090 lipopolysaccharide 1,2-N-acetylglucosaminetransferase" /codon_start=1 /transl_table=11 /product="glycosyl transferase group 1" /protein_id="ZP_05428410.1" /db_xref="GI:256003419" /db_xref="InterPro:IPR001296" /translation="MKIALICTEKLPVPPVAGGAVQLYISEILPYLKERHNITVFSKI HPGLSPDEVVDNVRYIRVPAANASKYVKNVKDLLDESFELIHIFNRPKWVLDFSEKLP SAKFSLSLHNEMFLPDKIPYEKAVECINRVEFINTVSKFIADGVKQLYPMAEDKLRVV YSGVNIEKYKPNWSPEGICNKELLKKKLGIENKRVILHVSRLSPKKGTHIVLSAMKKV MDCFDDVALVIIGSKWYGKNEEDDYTKQCKALAEQLSGPVVFTGFIPPSEIPPYYNVG DIFVCASQWNEPLARIHYEAMAAGLPIITTDRGGNAEIFEDNVNGIIIKDYKNPDSFA DNIIYLLNNPHTALEMGKKAFESALSRFTWKRVADEVLAPIQNFDQRITVNDNKTQSG LAKENIIEEDIMKENNDEKATEEKSTEEIETFFDDTNF" misc_feature 130062..131204 /locus_tag="ClothDRAFT_0377" /note="Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438" /db_xref="CDD:30787" misc_feature 130065..131180 /locus_tag="ClothDRAFT_0377" /note="This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801" /db_xref="CDD:99974" gene 131426..132412 /locus_tag="ClothDRAFT_0378" CDS 131426..132412 /locus_tag="ClothDRAFT_0378" /inference="protein motif:PFAM:PF01370" /note="PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: geo:Geob_1870 dTDP-glucose 4,6-dehydratase" /codon_start=1 /transl_table=11 /product="NAD-dependent epimerase/dehydratase" /protein_id="ZP_05428411.1" /db_xref="GI:256003420" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR002225" /db_xref="InterPro:IPR003869" /db_xref="InterPro:IPR005913" /db_xref="InterPro:IPR013120" /translation="MKVMLVTGGAGFVGSNFIRFFLRRNKNFIIINMDNLSSTSNLEN VKDLEKSPRYHFVKGSITNHELVNYVIKRHRPDCIINFASESSLDNCANNPLNFTQTN VLGTQTLLESARYFWGKNKFQGNLFIQVSTGEVYGSTPANDVFFSEEAPLLSDNPFSA SKAGADMLVKSYTITYGFPAIITRCCPTYGPCQHIGNFIPKCIINALSDKPITVCENK VREWIYVLDHCIALTKILFYGRTGEIYNISSGNEISDFDVAKKILGLVGKPDSAIEKA DDSSLPTKRCILNSYKLKSNLNWSIKFKLEEGLRETILWYKQNPDRWKNVEL" misc_feature 131438..132394 /locus_tag="ClothDRAFT_0378" /note="dTDP-glucose 4,6-dehydratase; Region: dTDP_gluc_dehyt; TIGR01181" /db_xref="CDD:130249" misc_feature 131441..>131980 /locus_tag="ClothDRAFT_0378" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" gene complement(132490..132753) /locus_tag="ClothDRAFT_0379" CDS complement(132490..132753) /locus_tag="ClothDRAFT_0379" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428412.1" /db_xref="GI:256003421" /translation="MYYYVGLESRTHAFLLEHRMKSEGMKTCEITYMPREIMIDLCNI GVRFKENELPKAIELLRRFNLQGLKLYKEVVRPDRYYYHEISY" misc_feature complement(132538..132753) /locus_tag="ClothDRAFT_0379" /note="Protein of unknown function (DUF3343); Region: DUF3343; pfam11823" /db_xref="CDD:152259" gene complement(132822..133562) /locus_tag="ClothDRAFT_0380" CDS complement(132822..133562) /locus_tag="ClothDRAFT_0380" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428413.1" /db_xref="GI:256003422" /translation="MHAHGPKIEAGQILNPECFPPPTELVCVQVPKVFDQVALRDCVT RTVCLKKGGDHCHSVFAFEGATDFDIVEVKVISKTDSLTKPGYKKLKLFVKIRYKIHY SDGSEQLSQTDEATFNLTVNEIYCPSCIAQVGVIKSNDDFWEGPTKTKDPDGTMIKVE ALAEAFNDVINPNTGVLSLDIGVFFIVKCECVVQLLIPSYGYCPVPPEQVNPAVQNCK TFNDRTKTPFPTKFFPDQKWNPLDQRSE" gene complement(133833..134099) /locus_tag="ClothDRAFT_0381" CDS complement(133833..134099) /locus_tag="ClothDRAFT_0381" /inference="protein motif:PFAM:PF04232" /note="PFAM: Stage V sporulation protein S; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="Stage V sporulation protein S" /protein_id="ZP_05428414.1" /db_xref="GI:256003423" /db_xref="InterPro:IPR007347" /translation="MSVLKVSAKSNPNSIAGALAGFVRENGTVEIQAIGAGALNQAIK AIAIARGFVAPSGIELICIPAFTDVEIDGVQKTAMKLIVEPRRR" misc_feature complement(133842..134099) /locus_tag="ClothDRAFT_0381" /note="Stage V sporulation protein S (SpoVS); Region: SpoVS; cl01005" /db_xref="CDD:154140" gene complement(134263..135045) /locus_tag="ClothDRAFT_0382" CDS complement(134263..135045) /locus_tag="ClothDRAFT_0382" /inference="protein motif:PFAM:PF00149" /note="PFAM: metallophosphoesterase; KEGG: gme:Gmet_1181 hypothetical protein" /codon_start=1 /transl_table=11 /product="metallophosphoesterase" /protein_id="ZP_05428415.1" /db_xref="GI:256003424" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR005235" /db_xref="InterPro:IPR006056" /translation="MKILFIGDIFGNPGRKAAKEMVQKLKKERQIDFCIANGENAAGG SGITYVVAQELYKYGIDAITLGNHTWSKKEIMNFIDSDSNIVRPANYPVELPGRGSTV ICGENGKVGILNLMGRIYMDSIDCPFKAAERELEYLKNNCKVIIVDMHAEATSEKCAL AWYLDGRVSCVLGTHTHVQTADERILPFGTAFISDVGMTGPYDGIIGVNREIVIQKFL THMPVRFEVATGRVQFNAVYLEIDEKTGKTTGIERIYEILEV" misc_feature complement(134509..135045) /locus_tag="ClothDRAFT_0382" /note="Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149" /db_xref="CDD:143917" misc_feature complement(134278..135042) /locus_tag="ClothDRAFT_0382" /note="Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382" /db_xref="CDD:163625" misc_feature complement(order(134515..134517,134521..134523, 134596..134598,134842..134847,134926..134931, 135016..135018,135022..135024)) /locus_tag="ClothDRAFT_0382" /note="putative active site; other site" /db_xref="CDD:163625" misc_feature complement(order(134515..134517,134521..134523, 134596..134598,134845..134847,134926..134931, 135022..135024)) /locus_tag="ClothDRAFT_0382" /note="metal-binding site" /db_xref="CDD:163625" misc_feature complement(order(134281..134283,134287..134289, 134392..134397,134404..134406,134416..134418, 134428..134436,134464..134466,134494..134496, 134500..134514,134518..134520,134557..134562, 134569..134574,134578..134586,134590..134592, 134650..134652,134659..134664,134668..134670, 134686..134688,134692..134694)) /locus_tag="ClothDRAFT_0382" /note="homodimer binding site; other site" /db_xref="CDD:163625" gene complement(135170..136744) /locus_tag="ClothDRAFT_0383" CDS complement(135170..136744) /locus_tag="ClothDRAFT_0383" /EC_number="3.1.4.16" /inference="protein motif:TFAM:TIGR03319" /note="KEGG: sfu:Sfum_2578 metal dependent phosphohydrolase; TIGRFAM: YmdA/YtgF protein; metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KH type 1 domain protein; SMART: metal-dependent phosphohydrolase HD region; KH domain protein" /codon_start=1 /transl_table=11 /product="RNA binding metal dependent phosphohydrolase" /protein_id="ZP_05428416.1" /db_xref="GI:256003425" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR004087" /db_xref="InterPro:IPR004088" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /db_xref="InterPro:IPR017705" /translation="MCAIAYLGGLLTGIVIAIIASIIASVISYRKGIEFRKKKAEAEI GSAEQEAERIISEAQKIAEAKKREVLLEAKEEIHKSRLELDREIKERRNEIQRLERRL VQKEEALDRKVESLEQKEELLNKKTKEIQELYEQTLETQRQQVAELERISGLSVDEAK EVLLKNVENEVKHEMAILIKDIEAKAKEEAEIRAKNIIAMAIQKCAADHVSEVTVSVV PLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARITLEK LILDGRIHPARIEEMVEKARKEVENTIRQEGENATFETGVHGLHPEIVRLLGKLKFRT SYGQNVLSHSIEVARLAGLMAAELGVDVNLAKRAGLLHDIGKAVDHEVEGSHVTIGAD IAKKYKESNEVVNAIASHHGDVEATSIIAVLVQAADSISAARPGARRETLESYIKRLE KLEEIANSFDGVDKCFAIQAGREIRIMVKPEDVSDSDIALIARDIVKRIENELDYPGQ IKVNVIRETRYIEYAK" misc_feature complement(135173..136651) /locus_tag="ClothDRAFT_0383" /note="phosphodiesterase; Provisional; Region: PRK12704" /db_xref="CDD:183692" misc_feature complement(<136388..136633) /locus_tag="ClothDRAFT_0383" /note="ATP synthase B/B' CF(0); Region: ATP-synt_B; cl07975" /db_xref="CDD:186725" misc_feature complement(135506..135739) /locus_tag="ClothDRAFT_0383" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076" /db_xref="CDD:185790" gene complement(136862..137539) /locus_tag="ClothDRAFT_0384" CDS complement(136862..137539) /locus_tag="ClothDRAFT_0384" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: nam:NAMH_1040 ATPase" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428417.1" /db_xref="GI:256003426" /translation="MEPGTLARYRSNIENFKQRYEKAKMYYYNQKGKMDQLTEQKTSL GTQLRKALYNIDVLEKVRLLLQKVSEYAREQSRVQIESLVTHCLQYIFDSNIEFKIEI NEVRGRPEAEFYVVSNFGGTQIKTKPQEARGGGVIDIISLAIRIAMLECSNLEIKGPI ILDEPAKHVSDDYITHVAEFLKQVTHMFQRQVIMVTHNRHLSEMADRWYRVEMKDGIS VVTGEES" misc_feature complement(136868..>137524) /locus_tag="ClothDRAFT_0384" /note="ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419" /db_xref="CDD:30768" misc_feature complement(136892..>137140) /locus_tag="ClothDRAFT_0384" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature complement(137117..137140) /locus_tag="ClothDRAFT_0384" /note="ABC transporter signature motif; other site" /db_xref="CDD:72971" misc_feature complement(137048..137065) /locus_tag="ClothDRAFT_0384" /note="Walker B; other site" /db_xref="CDD:72971" misc_feature complement(137030..137041) /locus_tag="ClothDRAFT_0384" /note="D-loop; other site" /db_xref="CDD:72971" misc_feature complement(136943..136963) /locus_tag="ClothDRAFT_0384" /note="H-loop/switch region; other site" /db_xref="CDD:72971" gene complement(137634..138491) /locus_tag="ClothDRAFT_0385" CDS complement(137634..138491) /locus_tag="ClothDRAFT_0385" /EC_number="1.5.1.5" /inference="protein motif:PRIAM:1.5.1.5" /note="PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: geo:Geob_1799 methylenetetrahydrofolate dehydrogenase (NADP(+))" /codon_start=1 /transl_table=11 /product="Methylenetetrahydrofolate dehydrogenase (NADP(+))" /protein_id="ZP_05428418.1" /db_xref="GI:256003427" /db_xref="InterPro:IPR000672" /translation="MEAKVLNGKELSTKIKEELKIEVEDLKKNNINPGLAVIIVGNDP ASRVYVNSKKKACAEIGIESFEYALEENTTQEELIELIHKLNKDDKVSGILVQLPLPK HIDEEKVIYAIDPSKDVDAFHPVNVGKLMIGNPDFLPCTPAGVMELIKESGIDITGKE CVVVGRSNIVGKPMAMLLLAQNGTVTVCHSRTQNIDEVCKRADILVVAVGKPEFIKGS SIKPGAVVIDVGINRLENKKLVGDVEYESASRVASAITPVPGGVGPMTIAMLMKNTVK AAKLQAKMK" misc_feature complement(137643..138491) /locus_tag="ClothDRAFT_0385" /note="bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190" /db_xref="CDD:184560" misc_feature complement(138132..138482) /locus_tag="ClothDRAFT_0385" /note="Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763" /db_xref="CDD:144385" misc_feature complement(137655..138149) /locus_tag="ClothDRAFT_0385" /note="NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080" /db_xref="CDD:133448" misc_feature complement(order(137889..137891,137916..137921, 137925..137927,137931..137948,137955..137957, 137964..137969,137994..137996,138012..138014, 138018..138020,138108..138110,138117..138122)) /locus_tag="ClothDRAFT_0385" /note="homodimer interface; other site" /db_xref="CDD:133448" misc_feature complement(order(137694..137696,137703..137705, 137799..137801,137805..137807,137850..137852, 137859..137861,137865..137867,137922..137927, 137991..137996,138069..138071)) /locus_tag="ClothDRAFT_0385" /note="NADP binding site; other site" /db_xref="CDD:133448" misc_feature complement(order(137691..137693,137712..137717)) /locus_tag="ClothDRAFT_0385" /note="substrate binding site; other site" /db_xref="CDD:133448" gene complement(138600..140519) /locus_tag="ClothDRAFT_0386" CDS complement(138600..140519) /locus_tag="ClothDRAFT_0386" /inference="protein motif:PFAM:PF08497" /note="PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gme:Gmet_0609 radical SAM family protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05428419.1" /db_xref="GI:256003428" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013704" /translation="MAFLPITREDMKNRGWDELDFLYISGDAYVDHPSFGHAIITRLL ESEGYRVGIVAQPDWRKDDDFLALGKPRLAVLISSGVIDSMVNHYTASKKPRSDDLYS PGGKSHRRPDRAVIVYTNKARQLFRDVPVIIGGIEASLRRFAHYDYWDDRVRRSILVD SKADLLIYGMGEKPILEIARYLSMGVPIKKIQNVRGTAFLARKEDLHGELRKFIDNSE DKPEKGYILLPSFEEVSTSKRKYAEAFMIQYNEQDPYTGSVLVQPHGDRFVAQNPPAY PLSEKEMDRIYSLPYERTYHPVYDKDGGVPAIEEVQFSITSHRGCYGGCSFCALNFHQ GRIIQKRSQASIINEARKLTWLPGFKGYIHDVGGPTANFRNKACKKQEISGACKERQC LYPKPCKNLIVDHSEYLELLRKLREIPEIKKVFIRSGIRYDYLMLDKNDDFFVELCRH HVSGQLKVAPEHVVDRVLEKMGKPQREVYDRFVKKFYEINRKIGKEQYLVPYLISSHP GSDLNAAIELAEYLRDINYTPQQVQDFYPTPGTLSTCMFYTGLDPRTMKKVYVPRSPK EKAMQRALLQFRRKENYKLVYEALKLAHREDLIGYGRKCLIKPPANLSKNNLKKDSSK RKLKKAGKSRRKSSR" misc_feature complement(139578..140513) /locus_tag="ClothDRAFT_0386" /note="B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase...; Region: B12-binding_like; cl00293" /db_xref="CDD:185888" misc_feature complement(138693..140504) /locus_tag="ClothDRAFT_0386" /note="hypothetical protein; Provisional; Region: PRK00955" /db_xref="CDD:179180" misc_feature complement(<138693..138929) /locus_tag="ClothDRAFT_0386" /note="Domain of unknown function (DUF3362); Region: DUF3362; pfam11842" /db_xref="CDD:152278" gene complement(140611..142071) /locus_tag="ClothDRAFT_0387" CDS complement(140611..142071) /locus_tag="ClothDRAFT_0387" /inference="protein motif:PFAM:PF01580" /note="PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: sat:SYN_01274 cell division protein" /codon_start=1 /transl_table=11 /product="cell divisionFtsK/SpoIIIE" /protein_id="ZP_05428420.1" /db_xref="GI:256003429" /db_xref="InterPro:IPR002543" /db_xref="InterPro:IPR003593" /translation="MQDNVEYRYPHTGLLDDNKMSLGNAENYRNSALKGAKKLEETLK SFGVDAKVVNVSVGPAVTRYELQPSPGVKVSKIVSLSDDISLNLAASGVRIEAPIPGK AAVGIEVPNKEVVPVFLKDVLDSKEFKEYNSKLAFALGKDISGQNVVADIAKMPHLLV AGATGSGKSVCINSLIISLLFKASPNEVKLLMVDPKVVELGIYNGIPHLLIPVVTDPK KAAGALNWAVQEMVNRYKLFADRGVRDIKGYNALLAKNGETEILPHIVIIIDELADLM MVAPNDVEDAICRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRIAFAVSSQVD SRTIIDMAGAEKLLGKGDMLFYPVGASKPIRVKGAFVSDGEVERVVEYIKSQGNAEYN ESIIDEINSEKENKNSDPGDNDELLPQAIELVVDAGQASVSLIQRKFKVGYARAARII DQMEARGIVGPFEGSKPRQVLITKQQLHEMNMKSEE" misc_feature complement(141142..141717) /locus_tag="ClothDRAFT_0387" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature complement(140647..140847) /locus_tag="ClothDRAFT_0387" /note="Ftsk gamma domain; Region: Ftsk_gamma; cl09645" /db_xref="CDD:158603" gene complement(142011..143036) /locus_tag="ClothDRAFT_0388" CDS complement(142011..143036) /locus_tag="ClothDRAFT_0388" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: mxa:MXAN_1460 FtsK/SpoIIIE family protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428421.1" /db_xref="GI:256003430" /translation="MKAKKTQKKKLTKKKSGIKKYNNEIVGIILLALGLLTVFGLFAE DSIGIFGTFIKTLILGLMGWLGYVVPLFIIFYSILVIFRKNNERVNSKIRYIFVLILI MSAMVQTLFYNEQDYINKGAVECIKKFFNDGAAMHGGGVLGGIISIPFLLLFKNLGTV IILTTIALIDIIIITDISIAGVFLRIKNDVAAIAAKVENRFKITKSELKEKLREEEEP ENETETEPETETEPDIDVVMNGKKISKILDFKKRKPPGKAGAAKRQTAILPNRLMIPV KMLKSMKSSLKTMKWILLCRILRKMALPKQKLRKIWTMSVWKSHQRCRTMLNTGIPIQ DFWMTTR" sig_peptide complement(142905..143036) /locus_tag="ClothDRAFT_0388" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 44" gene complement(143210..143434) /locus_tag="ClothDRAFT_0389" CDS complement(143210..143434) /locus_tag="ClothDRAFT_0389" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428422.1" /db_xref="GI:256003431" /translation="MILYSIVPPEIVFGNFDWCENQKQNYIEVDYCGEKVVVMPLSNN RYMISRVISTSPKAFLNPKLMPGNIITGTF" misc_feature complement(<143288..>143413) /locus_tag="ClothDRAFT_0389" /note="Trans-activating transcriptional regulator; Region: TATR; pfam03430" /db_xref="CDD:146193" gene complement(143431..144204) /locus_tag="ClothDRAFT_0390" CDS complement(143431..144204) /locus_tag="ClothDRAFT_0390" /inference="protein motif:PFAM:PF00574" /note="PFAM: peptidase S14 ClpP; KEGG: apl:APL_1268 protease 4" /codon_start=1 /transl_table=11 /product="peptidase S14 ClpP" /protein_id="ZP_05428423.1" /db_xref="GI:256003432" /db_xref="InterPro:IPR001907" /translation="MIEENKITVGRASVDETVSENEKKPEFEEIKELGKTSISSSKGN IHCLTVIGQIEGHMVLPPQNKTTKYEHVIPQLVAIEESEEIDGLLLILNTVGGDVEAG LAIAEMIASMSKPTVSLVLGGGHSIGVPMAVATNYSFIAPSATMTIHPIRLNGMVIGV PQTYEYFDRMQDRVVQFVTKNSNISKERFRELMLKTGELANDVGTILFGEEAVKYGLI DEMGGLKEALKKLYELIAKRKKNKNSISQGTVQKPEGLQ" misc_feature complement(143542..144051) /locus_tag="ClothDRAFT_0390" /note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase...; Region: crotonase-like; cl11392" /db_xref="CDD:187017" misc_feature complement(143827..143829) /locus_tag="ClothDRAFT_0390" /note="active site" /db_xref="CDD:132923" gene complement(144355..145644) /locus_tag="ClothDRAFT_0391" CDS complement(144355..145644) /locus_tag="ClothDRAFT_0391" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428424.1" /db_xref="GI:256003433" /translation="MNKKLKILAVSTLITATVFSTGCSVLFNKPPATDTEPPKIETPD TSAEEDKKVQEFMTEYFGALFGQNVESYKNNLLTGEIPANIKNYIAERTIKEGDKNPE VGIHFPRFVEVNGMTMLNYEILKDANNNPVIESDFIGKNGDAYLYYVRVGLKAKGLPN SLFHKYYVLNNETNVYEKIKENGVDKVVPEEDYDYIKVTAKYDVEVVKEGDGYKVLTQ KEADFKSPLSKRISKLNNEFIEKRQYLDENIPEEKQQLDNEKALLEQFFKNLLALDRE RMALLRAKWYEGYTGFMEFLSGLGINKVNDKEILFTDANYTQKFNIMSFPLQVNMERI ESIDNIKIIQHPGYTQKNKMYFVIFDASVVKANGMIGDKVVYKYDYTVSMKNKDNKLM IDEIKLNEFYQKKDTKQSEKKDEKKEEKRKEDTIDLM" sig_peptide complement(145558..145644) /locus_tag="ClothDRAFT_0391" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.681 at residue 29" gene complement(145672..148221) /locus_tag="ClothDRAFT_0392" CDS complement(145672..148221) /locus_tag="ClothDRAFT_0392" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428425.1" /db_xref="GI:256003434" /translation="MLRLLKKERGAALVTVIIITAVLTTLSVVLLNSAIQGLSLSKRQ SNIKLTYFAGQSAIEKWFNIIQKESEDQNIGAGFPDEVNATNVDRYVEMILDKVKLKL NDTEYIDVVSKAPTVAGLSGDDYSEIKLKALEVIGTPQLIEGGKKVKVVIGIEAEASF NNPNSPYGNTRQPLYAEKEFVFEVPQNDFKLTFAIATAADLYASTRSYHFNEEEENRN RNYVGDLRAAVPEFKVDIKGDVSAFGTFPKDILWPEQFYYGGIMAMHGAQVDIKGNAY SRAFIRTGPYRDVYRGLSEPAVFSDESRINIYRDAVAQCIQVFGNDNIISVFRNAYTF DDIEMNGERSIIAINGSAIGLSHYFESRNHDALSAIISSAPVHNLLSDDSLLSTIAVN GDVIIPGGTFRVDDDGIFTGLLEDASVFWYEDPNGIRIPFYKMYQWTEDDILNPDKYH AELRERLRNLSAAYLNGPFNLFQLWPSRERVNDDIETGGGLYDYVTNDFINSIKAVWG KRNAAEAGVSVPGAVSGAWSYELAANWRYYAGRLSTEGRDYEAVGVKGIDYVKRPGFA IDNIYKKDSYGNIIGLKFDFNLWNDVPEADDPSYTHKVFTKLDMSGEIGDPDNVKNNL LDYTQLLANRKYPTSGSEWDISGEHGIVKLIQKAKSQFSAYTANEYYIQVNPGLSKGQ YNLAALAGFDLYGRCQESRTGGTFESDTEYFLVFNENPEIDLIVDGTFNGIILTAGSV ILNGGADIRGAIISGGGGDRSAGEYELKLNRLDRDTFQAVALDRGRYAGVKMVPASNS DPGIVKVDFYLGLTTESEIIEKGRNDYLNMAARNNLLNKFAELGIYLYNIF" sig_peptide complement(148120..148221) /locus_tag="ClothDRAFT_0392" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.883) with cleavage site probability 0.273 at residue 34" gene complement(148298..148819) /locus_tag="ClothDRAFT_0393" CDS complement(148298..148819) /locus_tag="ClothDRAFT_0393" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: neu:NE1746 fimbrial protein pilin" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428426.1" /db_xref="GI:256003435" /db_xref="InterPro:IPR012902" /translation="MVRLFRKLNNNKGMTLVEVVVALALLGILVVPITIGFMNTIRIA KLIERQTEVNAVSEVVKDQVAEALIQQNYPLTLLESAPTGTEWYLRPFIADAKSTPDV EKKSPNLAVVYSSGAKNEKYFYTVSYKHESCYDPEYPYTYHVIVNILTKNNKGEIKTL NTFKIAANVNTTL" gene complement(148865..150157) /locus_tag="ClothDRAFT_0394" CDS complement(148865..150157) /locus_tag="ClothDRAFT_0394" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: similar to viral A-type inclusion protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428427.1" /db_xref="GI:256003436" /translation="MGKDKGKIALLIVLLLVLYGVIYYQFIWTPKFSLDIEDINSKIE TAQKQKQKLDNDLANIETLKRNLEMKTVQNERLETYLLNDSNVSDGFEYIEKLGKLFK NKLYNVKVKRPAEKKIGNSKDDKNAQSYYEIQIDFDATMTYREIMELVDYLEGGTRKV KITKFEVSPLGNKQANATPTPQNTAEPQTESDEQNAQNALAKAIFDPNEVLDLGMTVC MYSMNRENADKIYDFSRQNFQRYFEGDQVFFDDTGVALNSGEDSENISAGGSGGASGG SSGSGTDTVAVTGNAKPFGGDLGIYMQSFLTGGQNFYTYDNTTNKTINFRTKITPKVT MTFNGDTVDINVVGNAGNTYDMTGHVPKDTVEMHIVLNYNLTPIENKDLGVNVQIINN TDKQININLYDKVRRAKITDRNGNSIYKSSSVEKVTIV" gene complement(150157..150708) /locus_tag="ClothDRAFT_0395" CDS complement(150157..150708) /locus_tag="ClothDRAFT_0395" /inference="protein motif:PFAM:PF05137" /note="PFAM: Fimbrial assembly family protein; KEGG: ppw:PputW619_0384 fimbrial assembly family protein" /codon_start=1 /transl_table=11 /product="Fimbrial assembly family protein" /protein_id="ZP_05428428.1" /db_xref="GI:256003437" /db_xref="InterPro:IPR007813" /translation="MKGDINLLPEEIMSTTSYERPSSGSGVIKLVIGLILVGVVIGCS ILAPVLHIKMLERELAQLEKEITSEKYAEVKKVNADLASIDGVLAKKKTVLNQIDSTS YPINDIFVALKNAEPVGCTLTNIEFKNNKLKLTGIAKDNFVIAEFVSAIQRLSFLTLD SEVNVQNGNIFSFTLRVGGKDGN" misc_feature complement(<150232..>150555) /locus_tag="ClothDRAFT_0395" /note="Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166" /db_xref="CDD:32979" gene complement(150749..151309) /locus_tag="ClothDRAFT_0396" CDS complement(150749..151309) /locus_tag="ClothDRAFT_0396" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428429.1" /db_xref="GI:256003438" /db_xref="InterPro:IPR012902" /translation="MFKNNCKGVTLVEMIVVIALMGIMAPIIYAVLIGGLNNFAQGCN FIDQQYDIQDVIRQVRHDVQDAKTVEMWMTGDVAARGEEKLSSLVFTMNLPGEPEIKK EWKFEDDSLQLRIVNSGVAGEFVKVVDNIDISKSYFEYYENGDVKQLILHILPKQNDR IVNKAGNVQEEIITEYSVRYKSIVRY" misc_feature complement(<151112..151303) /locus_tag="ClothDRAFT_0396" /note="Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165" /db_xref="CDD:32348" gene complement(151417..151923) /locus_tag="ClothDRAFT_0397" CDS complement(151417..151923) /locus_tag="ClothDRAFT_0397" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: dps:DP1455 prepilin peptidase dependent protein D [precursor]" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428430.1" /db_xref="GI:256003439" /db_xref="InterPro:IPR001120" /db_xref="InterPro:IPR002416" /db_xref="InterPro:IPR012902" /translation="MKKMLKNQKGFSLVELLIVIAIMGVLAAIAFSMFAGVLGNAKRR ADERTADQIAKALSLYMTDSGDVNLTAFEDNSDPKVIIRQLQEKIAYTPVDEEGNPVG DEKYYGPYLTPKEGDTPAYENFAPQFKNHLGYKIVYYPSLQKADVKPVEEGNENGDEV GVFNGEEE" sig_peptide complement(151804..151923) /locus_tag="ClothDRAFT_0397" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.453 at residue 40" misc_feature complement(<151702..151920) /locus_tag="ClothDRAFT_0397" /note="Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165" /db_xref="CDD:32348" misc_feature complement(151831..151902) /locus_tag="ClothDRAFT_0397" /note="Prokaryotic N-terminal methylation motif; Region: N_methyl; cl06830" /db_xref="CDD:141948" gene complement(152078..153292) /locus_tag="ClothDRAFT_0398" CDS complement(152078..153292) /locus_tag="ClothDRAFT_0398" /inference="protein motif:PFAM:PF00482" /note="PFAM: type II secretion system protein; KEGG: geo:Geob_3372 type II secretion system protein" /codon_start=1 /transl_table=11 /product="type II secretion system protein" /protein_id="ZP_05428431.1" /db_xref="GI:256003440" /db_xref="InterPro:IPR001992" /db_xref="InterPro:IPR003004" /translation="MPLYSYKVKNEAGKLFTGEAKVDSEEELRRLLLDKGYTPVEIVE KNVINDISQIRLFKPRVKVKDLAVFCRQFSIVLEAGVPIANALDVLREQTTNRTLREC LDDVYDNIQKGIALSNAMRQHPRIFPEMLINMVEAGEISGQLDLVFKRMAIQFEKENK LNQKIRGALTYPIIVTVVAIAVIMILMVAVVPTFVKVLADFDVEMPIYTRILIAVSGF FKSFWFIILGALIVIGAGIAYFSRTYEGKIFFGTLAIKLPVIRGVTRNIMTARLTRTL GTLMSSGVLLIQAMEVVQKVLGNQVIREKIDGVIEEIKKGRGLTAPLAALNYFPPMVI SMIRIGEESGNLDFALDKSADFYDEEVEASLAMLTSFIEPAIIIFLALVVGFIVLSVL TPMFTIYNEMSI" misc_feature complement(152084..153292) /locus_tag="ClothDRAFT_0398" /note="Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459" /db_xref="CDD:31648" misc_feature complement(152777..153088) /locus_tag="ClothDRAFT_0398" /note="Bacterial type II secretion system protein F domain; Region: GSPII_F; cl00906" /db_xref="CDD:154078" misc_feature complement(152111..152479) /locus_tag="ClothDRAFT_0398" /note="Bacterial type II secretion system protein F domain; Region: GSPII_F; cl00906" /db_xref="CDD:154078" gene complement(153751..154806) /locus_tag="ClothDRAFT_0399" CDS complement(153751..154806) /locus_tag="ClothDRAFT_0399" /inference="protein motif:TFAM:TIGR01420" /note="KEGG: ppd:Ppro_2513 twitching motility protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="twitching motility protein" /protein_id="ZP_05428432.1" /db_xref="GI:256003441" /db_xref="InterPro:IPR001482" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR006321" /translation="MDINDLLRKTVENDASDLHICAGVPPIIRVYGDLINLNEPVLTP HDCVQLAKQCLSSRMYERFLEVGEVDASYSVPGVARFRVNVFKQRGTCAIAFRAIPTE VPSIEQLGLPGLVYDLAMKQRGLVLVTGPTGHGKSTTLAAMINYINSKRRCHIVTIED PIEYLHRHNKSIINQREIGSDTKSYANALRAVLREDPDVILIGEMRDQETIATALTAA ETGHLVLSTLHTVGAAKTIDRIIDVFPPHQQSQVRVQLSTVLMGIISQQLIKRANGKG RVLATETMVWTPAISNLIRESRTPQINTCIQTGSQFGMYTMDSCLAELYKAGEIDYES ACQYSVDMDNLRKLISN" misc_feature complement(153760..154806) /locus_tag="ClothDRAFT_0399" /note="Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805" /db_xref="CDD:32636" misc_feature complement(153844..154440) /locus_tag="ClothDRAFT_0399" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature complement(order(154396..154404,154414..154419)) /locus_tag="ClothDRAFT_0399" /note="Walker A motif; other site" /db_xref="CDD:29986" misc_feature complement(order(154195..154200,154327..154332, 154336..154338,154396..154404,154414..154416)) /locus_tag="ClothDRAFT_0399" /note="ATP binding site; other site" /db_xref="CDD:29986" misc_feature complement(154198..154212) /locus_tag="ClothDRAFT_0399" /note="Walker B motif; other site" /db_xref="CDD:29986" gene complement(154822..157185) /locus_tag="ClothDRAFT_0400" CDS complement(154822..157185) /locus_tag="ClothDRAFT_0400" /inference="protein motif:PFAM:PF00437" /note="PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; KEGG: ank:AnaeK_0656 type IV-A pilus assembly ATPase PilB" /codon_start=1 /transl_table=11 /product="type II secretion system protein E" /protein_id="ZP_05428433.1" /db_xref="GI:256003442" /db_xref="InterPro:IPR001482" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR007831" /translation="MLGVDTRGIDEILLEMGVLKIVDLKKAWDIQRESNKNIEDVLLE LGLVSQKDIMHANAVKMGIPFVDLSTYQISDSSVPLLITRNIANRYKVIPIEKENGVL TVAMSDPTDIFCIDDIRLATALEIKPVLADVKEIERLIVEYFGEEKKPQESKLKAENE EQNKKEELLKMEEELLGREIYNNIKADVETREPEFDLASKGFDQNTYNESGIFKDKIG NILVRAGVITQDQLENALSIQKKSGGLIGQILVKQGYIDRRSLYEFLQKQMGVEYVDI EGIEIDEDIIGLVSPNLAKTHKVIPIEKVDGNLKVAMSDPMNIFSIDDLRLTTGLEII PCLADEEQISAQLEKYYGKASRKTSAKEIEQKVADLDEEIKKVNEKIAVEITQTEDED TTIDISDLENAPIVKMVNIIFQKAVATRASDIHIEPQEDCVLIRFRIDGQLVEIMRYD RKILSSIVARIKIISGLNIAEKRIPQDGRIGIKIDDREYDMRVSVLPTMFGEKVVIRI ADKEGFNVSKKELGFFEDDLEKFDQIISSPYGIILVTGPTGSGKSTTLYTALRELCKP NVNILTVEDPVESTIKGINQVQVNVKAGLTFATALRAFLRQDPDIIMVGEIRDSETAE IAIRAAITGHLVFSTLHTNDAASSVTRMIDMGIEPFLLSSALVGLIAQRLVRRLCPHC KEAFQPDKNEREILGLKDDEEVTIYRAKGCDECNNTGYKGRIAVYEILTVNREIKELI SKNVSSDVIKDAAIKMGMKTLRMNCTRLVKEGITTIDEMLRIAYSID" misc_feature complement(156424..>157185) /locus_tag="ClothDRAFT_0400" /note="bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234" /db_xref="CDD:183046" misc_feature complement(156742..157062) /locus_tag="ClothDRAFT_0400" /note="GSPII_E N-terminal domain; Region: GSPII_E_N; pfam05157" /db_xref="CDD:147371" misc_feature complement(154834..156540) /locus_tag="ClothDRAFT_0400" /note="type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538" /db_xref="CDD:162908" misc_feature complement(156124..156438) /locus_tag="ClothDRAFT_0400" /note="GSPII_E N-terminal domain; Region: GSPII_E_N; pfam05157" /db_xref="CDD:147371" misc_feature complement(155017..155808) /locus_tag="ClothDRAFT_0400" /note="PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129" /db_xref="CDD:29995" misc_feature complement(155527..155550) /locus_tag="ClothDRAFT_0400" /note="Walker A motif; other site" /db_xref="CDD:29995" misc_feature complement(order(155338..155343,155461..155466, 155470..155472,155527..155535,155545..155547)) /locus_tag="ClothDRAFT_0400" /note="ATP binding site; other site" /db_xref="CDD:29995" misc_feature complement(155338..155355) /locus_tag="ClothDRAFT_0400" /note="Walker B motif; other site" /db_xref="CDD:29995" gene complement(157511..>157709) /locus_tag="ClothDRAFT_0401" CDS complement(157511..>157709) /locus_tag="ClothDRAFT_0401" /inference="ab initio prediction:Prodigal:1.4" /codon_start=2 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428434.1" /db_xref="GI:256003443" /translation="SLKTIIDCADKLMIDGVLFNNFYFVGVGKLRKAYDTYSIEYYKH VKENLKNIADVRMRTLQFFRG" ORIGIN 1 aacaattatc ccgttgttga catggaattt gcggaattta tggtcgaaag gaaaatcaaa 61 atccttggca tggatactcc ttctcccgac aagccacctt ttccggtcca caggctgcta 121 ctaaaaaacg aaattttcat cctcgaaaat ctcgcaaacc ttgaagcgct ccttgatgtt 181 gaaaagtttg aagttatagc ccttcctctt aatataaaag ctgacagttc aatcctgagg 241 gttgtggcaa aagtagtatg accttataag aaagcctttc ttcccggttg ccgttttcat 301 tatcgggaaa aagggctttt ttgctttttt cattgattct tttcaatttt tctattttta 361 ttatcaaagt ctttttttct ctctcttaaa ttctttttta accggttata gctttcttta 421 tctccgttaa aaggtactat tccccccgta tagctgacaa gtccgtaata atcttctttc 481 aaatgaggaa atgccccatc attaagtgtc agataaaaca ccgattcctg attcatctgc 541 aacttgtctt ccacataatc aattatcatt tcggaaacag ccaggttaac cgttttatgc 601 ttttttcccg taccatttac tatcgtatcg gtaacttcaa gttcatatac catgcaagga 661 acttctccaa ccgtaaaagc aactcccttt atacctttta atttcccctt tacaatcaag 721 ctaccttcgt caaaataata ttcatcagtt aatgggcctt catccaccaa tgcaataata 781 tcacttttgc cgtattcttt ttcatactcc acatgactta acaacacatc tttttcctcc 841 tgtttatcat tgtcttgaga attcccgaaa gcaacgcaac ttattgaaat aattacacaa 901 agtaaaatag taaaaacaat tgtcaaattt cttctcatat tcccattctc ctaaaaatat 961 attttcataa tattttttta tctcatttga gataagagtt tttcattaca ccatatacac 1021 ataatacgta gtaaatcagt tgcaattata tctttatacc ggttaattac aataatatat 1081 cactaatcaa caaattatta catttaacaa gaacatactt gttcatattt atacaagtca 1141 agttaatttt tctttacatg aaaaacttac ccagtttttt aattaaaatg tgccaataaa 1201 ctttcacacc cacccgggta gctaatagtc acttttttaa atctggacaa caggggacct 1261 aaaaaaataa tagaagatct catttccgtt gcgagatctt caggaatttc ggtgctgtta 1321 atcgttgaag aatcaatcgt aacaacatct tcttcaaact taaccttgca acctaatttc 1381 cttaaaatct caagcattat ttccacatct ctaagctttg gacaattctt tatgacactt 1441 ataccatcat taagaaccgt ggcggcaaga atgggtaaaa cagcattttt tgacccttct 1501 acaactattt cgccctttag cttccggcct cctgttacaa ttagcttact cataatacac 1561 ctccgtaaca ttcggtggtc aaattcaaac catctttttt ccattgtata atggtataaa 1621 tataaatata aaattatatg tatacaattt acaaatataa ctatatgtat ataattattt 1681 tatgctgggt ttacaaaaat gttactttgg cgattatata aaaaaaggac tctttttcga 1741 gtccttatgt ctaaccggcc gctttgtttt tcataatgtc ttttattatt tcataaattc 1801 tttccgttgc atttgtaata cctatgctct ttgcgttctt agccatttgg gaaagcttat 1861 ttctgtcttt taaaagtgtt gtaatttcct cgtacaatat atccggcctt aagtttttct 1921 ccagaattac caccgaagct ccctgccgtt ccaaggccct ggcgttgtgt tcctgatgat 1981 tggccgtaac ataaggtgac ggaatcaata tcgaaggaac acccagggca gtaagttcgc 2041 ttaccgttat tgctcccgcc cggcatacca caaggtctgc tgctgccatg gcatttgcca 2101 tgtcaaatat gtacggcaaa atattaatat tgggtgattt cacttccccg attttcttca 2161 ttataccatc atattgagct tcgccggtcg catatatcaa ataaaatccc aaatcacttt 2221 tatgtctttt tataagctcc gccactgtac tgtttatatt ttcagcaccc ctgcttcctc 2281 caaatatgac aaccaagggc atatctttgg gtattccaag cttttttcgt gcagtctctc 2341 tgctaacttc cagcatttca cttcttatgg gatttccggt aaataccact tttgatttgt 2401 ccttaaaata tttttccgct tccttaaagc ttattgccac cctgtcaaca aactttgaca 2461 gtatcttgtt tgtcactccc ggaaaagcat tctgttcatg aacaagggtc ggtattttca 2521 ttcttgaagc attaaacaat accggtccgc aaacatatcc tcctgtgcct atcaccaaat 2581 ccggcttgta atcctttata atctttcttg cctccgcaag cccttgaaac aattccttca 2641 ccgcaacaag agtatccatg gaaagctttc ttttaaatcc tcttaccttt atcatcttta 2701 tctcaaaatt ttctctcggt acaagcctgg cctcaagtcc tctctcggtt ccgataaaca 2761 aaatctctgt atcgggttcc ctttttttga tatattttgc aattgcaagg cctggattaa 2821 tatgtcccgc tgtacctccc ccgctgataa tcaccttcaa aatcaactca cctcagattc 2881 tttcataatt tgcatatttg gaaatattaa gaagtatgcc cactcctgcc atcaggaaaa 2941 taagagaggt tcctccgtag ctgaagaacg gaaggggcat tcccgtaacc ggcatggaag 3001 atgtaacaac cgcaacattt ataatcgcct gaaaagcaat cagcgaagtt attcctatgg 3061 cgaccagact tccaaaaacg tcaggcgcgt tcatggaaac tttaactcca cgccatataa 3121 agataaggaa caaaagaagt accagggcaa ctcctataaa tcccaattcc tcggccaata 3181 ccgccagaat aaagtcatta tacggttcag gaatataaag gaacttctga agactgtttc 3241 ccaatcctct tccaaacaat ccgccggaac caatggcata aagggattgt ataacctgcc 3301 atcctgctcc ttttgggtct tcccacggat ttaaaaagga taaaactctt ttcatcctgt 3361 attcggaagt aaaaatcaaa taacttaccg ccgcaacagc aggcactccc attaatacaa 3421 aatgttttat ctttgctcct gcgcaaaaaa gaattacaca cgataccaaa cctataataa 3481 ttgtcgcact catgtggggt tccaaaagca gcagcaatgc atgaatacct atcagtatca 3541 ggtatggaac aagacccctg aaaaagtact tcaggctatc ctgcctttta gaaagactgt 3601 aagacaaaaa cagtatcata gccagcttgg caaattcaga aggctgaaaa tcaacaaatc 3661 caaggtcaaa ccaccgggtt gcattgttac gggtggcacc gattccgtca atccacacaa 3721 cagaaagcat ccctaaactt acaagcatga taatgggcga caatttacca agttttctgt 3781 agtcaatatt cattgtgaca aacatcgcaa aaagtcccac aggaacatac agcaactgct 3841 tctttaaaaa atgatacgaa tcacctttca tatagttata tgcatgggga gcactggaac 3901 taaataccat tatagaacca atggtaagca ttatcaacac agtcagaaat attaaaaaat 3961 caaacggctt tttagttgta attgcagatt tcattgttga agattttatt gctgcagctt 4021 tcatcgtttt ccccctctga aattcggcct taaaagcagt taatattttt ggccggattt 4081 ttactttgca aaatcgcggt taaatcaata aaatttaagt ctcagcgcaa agaaaccaag 4141 gatgcaaaga agtaccgtta ttgtccaaaa taccagaacc acctttactt ctttccagcc 4201 tgaaagttca aaatggtgat gaataggtgc cattttgaaa actcttttgc ctgtcagttt 4261 aaacgaaagc acctgtatca taaccgacaa tgcctcaaca acgtaaatac cgccgacaat 4321 caacagtatg agaggcattt tcatcaaaat tgcaattgca cctacggcac cgcctaatgc 4381 caaagaacct gtatctccca taaaaattct tgcagggtac gcgttaaatg tcaaaaaacc 4441 caaacatcct ccggcaacca tggccgaaaa catttttatg tattcccact cgcttctggt 4501 cattgccact atggtgaaaa agacagttac tatcaaagtc actcctgctg caagtccgtc 4561 caacccgtcg gtaatgttca ctgcattcgt tgaggctatc aaaacaagca caacaaatgg 4621 gacaaacaac catcccagcg acaccgtttt atccattccc ataaaaggaa taatgatgtc 4681 cgaagtatgg gtatgagaca aataaacggc aaaagtgaca gccaccaaaa gaagaccgaa 4741 cattttttga ttccagtaaa gaccgtcttt ccttttcttt accactttta taaaatcgtc 4801 aataaaacca ataagcccaa acccaagagt tacaaaaata agaggaagaa tcctcctgtc 4861 atgtcctgca taaaaagctg caagaacagt aacaggtatg aggaaaatca ttccccccat 4921 ggtcggcgta cctgtctttt tataatgagt cttcggtccg tcatccctta ccgtctgacc 4981 gaacttcaaa cgcgtcagca tcggtataag cacaggacct aatatcagtg aaaaagcaaa 5041 actcaatata aatacaaaaa catgcggtga aatattaaac ggcaaattca atttcacact 5101 cccccattaa tactaaatgt catcttgctg taaattgtca aaaagatttt ataccactcc 5161 aaatttacac ctttaagctc agccagtcaa tatattaact atttcctcca ttttcatacc 5221 tctcgaaccc tttacaagaa gcacatcacc gctctttaca aattctttta aaaactttgc 5281 ggcatccata ttgtctttaa attcaaaaac cttttcttct tttgctcctg cttcaacggc 5341 accacggaca atattacttc tgtactctcc cacggccaca atataatcta tcccttttga 5401 agcagcatat tttcccactt ccatatgagc acttttagag aattccccca gctcaagcat 5461 gtcacccaat acggcaaagg ttctgccttc accggatata tcctttaaaa cgtcaatagc 5521 cgcctccatt gactggggac ttgcattgta agcatcgttt ataatcttta aaccgttata 5581 gtttataata tcaagtctca tctttcccgg ggaaaactct tcaattccct caactatttt 5641 ctccggcggt attccaagct caattcccac tgctatacct gcaagggcat tgtaaacatt 5701 atgaattccc ggcacaggaa ttctcaccct gtattctttt cctctaatct caatatcaaa 5761 agtggagcct ttttccccca aagattccac attgtatgcc cgcaaatcca gcccttcctc 5821 cattccgtaa aataccgtcc tgaacttcaa aaggttgttt aatccataca ataatttgtc 5881 atcaccattt agtattgcca atcctttctc atttaagccc tcaaaaatct ccatttttgc 5941 ttttaatatg ttattttttg aacccagctt ttctatatgg gatactccta tattggttat 6001 tattgcaata tcaggtttta ctatagacgt aagacggctt atttcgccaa aaccgctcat 6061 gcccatttcc acaacggcag cctcgtggga tttgtcaagg ttgaaaattg taagaggcac 6121 accgatttca ttgttaaaat taccctggtt cttcagcacc ttgaagcctt ttgacagcac 6181 tgccgcaacc atttccttgg tgcttgtttt ccccacactt ccggtaattc ctacaaaagg 6241 gatcttgaat ttttgtctgt aatacaccgc aagatccctt aaagccttaa gtgtatccga 6301 aacctttatt aaaactttgc cgggaaatgg ttccgtttcc ttttgagtaa ggctgcccag 6361 agctccatgc tccaaagcag acgcaatata gttgtgtccg tcaaatcttt ctccaataag 6421 aggaataaac aaatctccct gttttatatt cctcgaatcg gtggaaatgt tataaaaaac 6481 agtattgact tctccggata ttaaagtgcc gccaaccgct tttactactt cttcgcattt 6541 taaaatttcc attcaatatt ccctccaggc cggttaatta ttgccactgt ccaattcctt 6601 caatatatcc cttactactt ccctctcgtc aaaatgaatt gttttatctt ttagaattat 6661 atatgtctca tgtcccttac ccgcaaggag aattatgtcc tttggcttcg cattcatcaa 6721 agcatatttt atggcttcac gcctatcggt aatcgtagta tacaaaccac ctgtctgttt 6781 aattccttct tcaatgtctc ttattatggc atccggatct tccgtccggg gattatccga 6841 agttatgatt gtaaaatccg ccaattgtcc cgatatcctg cccataatcg gtcttttggt 6901 tttgtcacgg tctccgccac agccgaatac acaaactact cgtccgggag catatgcttt 6961 taccgtggtt aaaatatttt caagactgtc aggggagtgg gcatagtcaa tcattacggt 7021 ataatctttt ttgatatcaa gaacttccgc cctgcctggg acagttacct tttccaaccc 7081 ttttttgata tattcaaagg gaactcccat aagagcacag gttcctattg cggctaaagc 7141 attatataca ctgaattttc cgggaatatt cactctgaca tccccggtaa accaagggga 7201 aacaaccgta aaatccacac tgtccgggtg atgtacaata tccaccgccc tcaaatctgc 7261 tttgttgtct atccccattg tatagacttc gcacctggcg ctgtccacca ctttcggtcc 7321 aaattcattg tctatattta ttaggccttt tttacacatg ccaaaaagct tgattttcgc 7381 attaaggtaa ttttcaaaag ttttatgaaa atcaagatga tctcttgaaa ggttggtaaa 7441 cacccctatt tcatactcac agcagcttac cctgtgaagc tcgagagcat gagaagacac 7501 ttccatcaca acactgttta cgtttttttg caccatttct gaaaaaagtt cttgaagatc 7561 gtaactttcc ggagttgttc ggtccgtcgg aagaacttcg tgtcctatca tatttgctat 7621 tgtaccgaca agtccaacct tttgcccaaa ggcttcaaga attgatttaa tcatgtatgt 7681 agtggtagtc tttccttttg taccggttat gcccacaaga ttaaacttgc ttgacggatg 7741 cccgaaaaaa atgtcggcca cgctggcaag agcatatctt gtatccttaa ccctgacaac 7801 cgtcgcgtca tcgggaacgt caacatcttt ttgaaccaga aaagctctgg tcccattctc 7861 aattgcctgg ggaataaact tgtgtccatc caccttaaag ccttctatac agacaaagag 7921 agaacctgct tttgcttttc tggaatcata agcaatatcc ttgatttcga catccatatc 7981 gccttcaact tcaagtacat taagtccttt taccaggtct ttaagtttca taaaaatcct 8041 cctgtcaaat tacgctttcc acgttttatt ctacgttttt ataatacatt tgtacagtgt 8101 ttcgtcggct aatgcgtatc aaggaataca aactcaacct caaccacctc gccctgaggt 8161 attttggttc ccggttcaac gctttgcttg accgcattac cgtttcccac aacttttata 8221 ttaagtcctg cggcattcaa agctttggtc gcttcatcaa ttgtcttgtt ggtcacatcc 8281 ggtacttcaa ccattatttg ttcttccggt tcgtaggtat acataataac aacggatttt 8341 tttgcaagct gcgcacctgg ctttggagtt tgctctttaa taatcgcatt tccgtcagtg 8401 ctgtcccctt ctattctata ttcaagtcca tattctttta gaatcttttt tgcttcatct 8461 atagttttgt ctcttacatc gggaacatat acctcttctg ctatcatttc catgtcttta 8521 tcggtgtatc ttctttcaac tccaagatag cttaatgttt cctccactat tttacccgcc 8581 accggcgcag cgatagttcc tccgtaatat gattcacctc ttggattatc caaagccacc 8641 agaacacata tccgaggatt gtctgccggt gcaatagctg caaaggaggc tacatacact 8701 ccttcaacat cagtttccga agtacctgtc tttccagcca ccctgtatcc tttaacatac 8761 gcatttcttc cggtaccttc agataccact ccttccaaaa catccagaag ggtttggcaa 8821 gtttcttttg aaataacatt tctcacaacc tgaggttcga atttctcaac cacatttccc 8881 tctgagtcaa caatctcttt tacaaggtga ggttttataa gctttcctcc gttggcaatc 8941 gccccatagg cggcaatcat ttcaagggga gtaactttaa atctctgtcc aaaggatgca 9001 accgccaagt caatatccgt cggttttgca tggaaatttc cctgagcttc tccaggaagc 9061 tctatacccg tcttgtcata aaatccaaag gcccgaagat aattgtaaaa cttgtcaaca 9121 ccaatatcca atgctacttt gacaaaagct gggttacagg aattgtacac ggcttccctg 9181 aaagattcct ctccatggaa attctccttc caacacttta tattatgtcc ctggacagta 9241 atggttctgt cactggttct tgtttcggga gtcacaaccc cttcttcaaa tcctatggcc 9301 gttgttattg ccttaaaagt ggaacccggt tcataggtat ccgaaaccgc cttgtttctc 9361 catactgtcc tgtacaaggt ttccacatcc ttctgtgaag tcccggtcca tgtggcagga 9421 tcttctgacg gcgggcaggc tctgggatcg ttgagattaa aatcaggttt tgataccaac 9481 gccagaattt ctccgtttct gggatccatc acaatggcaa aagcaccgtt tgccaccttg 9541 ttgtcctcta tagctttctg caaagcttcc tcggcaaaat actgtatgtt ttcgtcaatt 9601 gtgagcacta cattcaaacc atcctgaggg tcaatacgtt tgttttcata gttgggcatc 9661 tgccttccct gggcatcgac ctcacttaag attttgcccg gcactccctt aaggtatttt 9721 tccatggttt tctcaatacc gtccaaaccc tgattgtctt ccccgacaaa tcctattaca 9781 tgggccgcaa gatttccctt tggataatac ctttttgtat cctcgtcaat atacagaccc 9841 ttgatttttt cttcactttt ccactgtctt atctggtcgc caatgctctt ttcgactctc 9901 ttctttatta tctcataccg actgttggtc ttgtttattt tctttaatac tgcttcctca 9961 tcgaggtcca aaaactctgc aagttttttt gcaatttgct ctcttacttc cggtgacttg 10021 tctatctccg tgggatttac cactattctg tcaacagtgg cacttatggc aagctgcttg 10081 ccgtttctgt caagtattga tcctcttctc ggaggtattt cccggtcgct gttttgctgt 10141 tcgtaagctt ttctctgcag ttcctcgcct ctgacaattt gaagccatcc aactctacct 10201 aataaagcta ttatcaaaaa agtaaatatc aacaatactg ccaaaagcct ttttttcatc 10261 accaaagtcg tgcctgccaa ccgaatccct ccagtaccgt tcttaatatt ataaaaaact 10321 gcccactaaa tttaagccac acaaatcttg ccccaaataa aaagaactgt atttcttctt 10381 aaggcttact taaaatttaa cgtgcagttt tacaaaaaaa taaaaatata ttcttttata 10441 ccggcaatat tatcatttac ttgtctttaa gcagcaagct ttaatacaaa agattggcaa 10501 gcaaattaac cttgttaata atgacagaga atatgccggc atttttcatt tcctcctctt 10561 ttgccgcttc agatactatg gtaaggtcgg tttgaggaac cctcacatat gtaatctgat 10621 gcttgtcagg tttgtgcatt ccaagctctt tttcggcaaa ttcctttatc ttctgtatgt 10681 caatactgtt ttctatttca acttttatcc tgatgttttc attttttaat tcattataag 10741 ctttaagttg tttgtctatt tcataattca tctcagttat acgggaatat ctatacatcg 10801 ctagggatcc catggcaaat acaagcagca gacaaagaac aatcttcctt ttaactttgt 10861 tgttgttcct ttgtttcttc ttggcattta gtaccgcgtt ttcttcatat acgtcatata 10921 ctaattttct ggctgccgta ccgtttatgt aattcttatc ctctaacata tgtattcacc 10981 tcaaaccgat tatattccca ttaaacagac aacaaatccg ggggtcagct aaaagcatac 11041 ccacccggaa taatcaatca aaaaccgtct gccgtaaggt tttgtctttt gttatgctac 11101 ttaattctct cttttccaat ttggctttca tcttttgttt actttcttgc tttgtctttt 11161 gtgtgttttt taataagggt tttcatttgt tttttgagtt ttgttataat ggtataactt 11221 tttcttttgt attaagtttt aaaaaaattt ttgccttaat tttggacttt gtcttttgtt 11281 tttaagtttt ttgtcttttg ttgtttttct actttttggt ttgcttttgt gtttttaaca 11341 ttttatcttt tgtatatttt tacttttatc ctttgctgtc gcctcagttt gtatctattt 11401 aaatctttta aattttttcc agaactctaa gttttgcact tcttgctctt ggattttcct 11461 caagttcttt ttccttcgga actatcggct ttctgtttac aagtactcct tcaggttttc 11521 ttccgcatgt gcaaaccgga aattgtttcg ggcaaataca agggtttact ttcttgttga 11581 actcgtcttt cacaatcctg tcctcaagag aatggaatgt tattatgcaa aaccttcctc 11641 cgggctttag aagctctgta ccgtcttcaa tagttttggc aagtatccca agttcattgt 11701 ttacagctat tcttaatgcc tgaaaagtcc tttttgccgg atggggacct ccccgtcttg 11761 cagaactcgg tatcgccgct ttaataatgt caaccagctc tcccgttgtc tcaatttctt 11821 ttttctttct cgcctctaca ataaactccg caatccttga cgcccatttt tcttctccat 11881 agtcccgaat tattcttttt atttcctctc tgccatattc attgactatt ttctttgcag 11941 taagctctcc tcttctgtcc atcctcatat ctaatggagc gtctttgttg tagctaaatc 12001 ccctggaagc ttcatcaagc tggtgggagg aaacccccaa atccaaaagt atgccgtcca 12061 cagactcaat attgtttttt tggcagactt ccttgatgtt tacaaaattc gtatttacaa 12121 ggataatttt tgccttcgaa tttatttggg ccagtttttc ctgtgacgtt ttaattgcga 12181 attcgtcctg atccaaacca attagtgtac cgctttcatc gagccttttt aaaatttcgc 12241 cggaatgccc cgcacctccc acggtgccgt ctatgtatac tccgtccggc ttgatggcaa 12301 ggtttgaaat ggtttcttcg agcaaaacgg gtttgtgttg aaattccatt tagattaacc 12361 aactcctatg tcagaattta ctgtctttcc aatcgacctc agattcccag catcgccatc 12421 ttttcagcta tgctttcggc actcatattt tcatccccag aatagctttc ccatttgctc 12481 ttatcccata cttcaaccct tgtggataca ccaattatat acacatcttt ttccaagccc 12541 gcatattccc ttaaattctg cggtataagt atccttccct gcttgtccac ttctacttct 12601 gcggcacctg caaagaagaa tctgacaaac gctcttacat ctttatccgt gaatggaagt 12661 gatctaagct tggcttccaa gttgctccat tcttccagcg aatacgcaaa caaacagtta 12721 tccaggccct tggtcaatat aaatttctca ccaagtcctt ctctgaattt ggaaggtata 12781 atcaccctgc ctttggcatc aactgaatgt tggtattcac cataaaacaa caatttcacc 12841 tcacattttg gaacaactca ccacttcgca ccactttcca ccacttctac ttcaatttta 12901 gttgaaattc acccaataat caagtctatt ttaaaaattt cctgataaaa aaacaaaaga 12961 taggaaacta gtcctatctt ttcatgataa atttagttta taaacattac ctttcgtact 13021 gcctttctta ttacctttta acttcaatat ggtttaccgt tccactttta ttccatatct 13081 atccactata aaaacttttc tgtcttcttg ccgacacact taaaaccact ccgatggcaa 13141 tatagttggt aagcatcgca cttccaccct gacttacaaa gggaagagga atacccgtaa 13201 ccggaagaag gccgatgctc ataccaatat tttctatgaa atgtattgca aaaaacgcag 13261 ttataccggc aaccacaaaa gttccatatc tatcccttgc atttttcaaa atatacaaac 13321 acctcataag aatgcaaaat accagtgcca caattataat tgcacccaca aatcccaatt 13381 cctcaccaac cacggaaaat ataaaatccg actcttttac gggtaccatg gaattttgcg 13441 tctgaatgcc cttaaaaagc cctttaccga aaatcttacc cgatcctatg gcaatttttg 13501 accggataac gttccatccc gctcccaaag gatccaattc agggttaaag aaaaccctta 13561 ttctgtcctt tcttttatca ttgagcacaa aaaaccacat aacaggaaaa gaggcaactg 13621 ccacacccat cagcatcaaa atatatttat agctgattcc ggaaacaaac aacattacaa 13681 aaaccgcaaa tataaatacc aaggtagttc caaaatcctt ttgtgccaaa accagtgcta 13741 tcggtatacc agagtatacg aaaaacttta tcatattggc agtcttattc ttttgcccgt 13801 catatattct ttccagaaaa atggacgaaa ccagcaccat cgatatcttc gcaagctcag 13861 aaggctgaaa actgaaaccc attatattca gccagcttcg gcttcccaac ttttctcccg 13921 tacctatgaa aagaaccagt accaataaag ccaccgtgaa aatatagaac ggtattccca 13981 gtaccttaaa atccttataa tccagtaaac tgataatcag agccaaaaca gtacctactg 14041 caatacttcc catctgtacc agaaacattc tccgtccgcc gggcattgta gccaccgcac 14101 ttctcaaaac aaaagccccg ataatggata acaaagtaac cgcagaaaac agaaagtagt 14161 caaatctttt gaggatattg aagtttttcg tcttttcaac aaaatacata caatgccacc 14221 ttccaacggt tgatacgtaa cctgccacca tatattacaa acaataatta aaaactactg 14281 ccaagctcat ttacatccat tgcctgacag tagtcaaagt actgataatc ataatataat 14341 tatattttta taccgaaata aagtcaaccg attccaaaat ttaaccattt gaagttctca 14401 aaataacctt ccctttatct aattcgaatt cttcctcccc aacaattcgt tatagtactg 14461 gacgattaac atatcaagct ttacactcag ctcatatatt tttgagtaat cgtcaccgtt 14521 gtcaatcata tcatttaatt gactttgcaa atcttgaatc ttcaattgca tttaatacac 14581 caccgtttat cttttgtata attaagctac acgacgtcaa aaccaaaatt ttgacatcct 14641 tatttgtttt ttgttcctct attataaaaa aatactaatt atgagtcaat actattcgaa 14701 aaatgtaata ataatgtaat atttgatatg aacatgtcag atatagtatt tttttattgt 14761 aaaccttgat tttcttcaac actttcttcc ttattttgat tttcggtgtc gcattctgtc 14821 tcatttgcga aatctttcgc gtcagaaacg gtatcgcagg aatggcccaa agcattatag 14881 accggttcac ctttcgaagt tctgtgcctt acaattatta tcacagcaaa agttatcgca 14941 aaaacaacgg caagaacctg ggaaatcctg aaaggtccaa gataaaggct gtcggttcta 15001 agcccttcaa tccatgccct gcctataccg tacaagagca tatagaagga aaacagttcg 15061 ccacgcactc tgtatctttt tctgtaccaa atcaggaaaa agaaaacccc gaaattccag 15121 agggattcat acaaaaacgt cggatgaact ggcattgcag gatcaatact gctgtcaccc 15181 aaagtcctta aataactttc aattgcctcg ctgtgcattc cccagggaag attggtattt 15241 gtcccgaagg cttcctggtt gacaaaattc ccccatcttc caattgcctg ggccaggaca 15301 aagtatggag agccaagatc ggccaggagc aggaaatcta tcttttttac tcttgcaaaa 15361 aaatatgccg taattaccgc tgcaattaat cctccataga tggccagccc accggttctt 15421 atattaatta ttttctttaa atccccgtta aactcatgcc aattaaaaac aacgtagtaa 15481 agccttgcac ctatgacagc tatgggtgca ccccaaagaa caaggtctat tgcatcatcg 15541 gattttatac caaacttttc actgtttcta agccctaaaa caaccgcaag gaaaaaacct 15601 gccgcaataa ttatcccata ccaatagaca ggtatgccaa aaatacgaaa ggcaacattg 15661 tttatggtaa attccaatcc cagtttggga aacttcacaa catttacggt ctccataatt 15721 atcccccttt tttctatacc gggtttacca ccgatacagc cagattatcc aaattgaaat 15781 gattctcaaa aacctctttt acataatcaa aagtcatatt gtcataaaca tccggatagt 15841 caaacatgct tacatcttta aaatacaccg atataaacat gtgcgaaatt ctctccaccg 15901 agttgagctg ctttatgaat cttcctttca tggctctttt aatccgttcg tagctgtttt 15961 tgtcaagccc gttcgcctgt attttcctga tttcatccac gactctttct tttaccatca 16021 agggatcttt ggattcgcca ccgaaagccg aatatgcata attctcttca atggtgtaat 16081 caaaatcaaa ggtgttgttg ataagaccct cgttgtacaa ctcgttataa aggcttgaac 16141 ttctgcccat tatcatttca agtatgagct ttaccgcaac ttccctcttt aagcactcaa 16201 ttccctttga attaaaatca ttgtctttaa atcccatttg aaacatgggc atggcaaccg 16261 caagcttctg ttcaacatag tcccggttga ttgttttggg ttcctcggga aaaatcctct 16321 ttatttcagg cttgctgctc tttgcatcta tactttcctc aatctgtccg aacacttctt 16381 tcggttcaac atctccaact accagaatca tcatattgga aggatggtag aaagtattat 16441 agcacttgta caaaatgtct cggttgattt tgcttatact ttcaaccgtt cctgctatgt 16501 caatttttac aggattattt acataaaatg catccagcaa gttgaagaaa actctccagt 16561 tcggatcatc ttcatacatc ctgatttcct gagctattat gtccttttct ttttccacgc 16621 tttcctctgt tataaaagga ttttgaacaa aatccaaaag gagtcggaaa ttgtcctcga 16681 acctgtcagt gcaggaaaaa agataaaccg tctgggcaaa gcttgtatat gcattgggat 16741 ttgaaccaag ctgtgaaaac ttatccataa cgcttccgtc tttttgttca aaaagcttat 16801 gctccaaaaa gtgggctatt ccgtcgggaa ctctgatgga atctttttcc ccgggcacga 16861 caaactcatt attgatggaa ccgtaatggg ttgcaaaatt cgcatatttt tttgaataac 16921 cttttttggg caccacaaag gatttaagac cgcttgaatg ttcatgaaca tataccgttt 16981 catcgatgtt tttatattca acaactttca tattcatatt gcctagaatt ctcccttcta 17041 tttttttctg tcattactct tcctttgatg ttaagaaata aaccgtatca agttttattc 17101 tttcggcaat atccacaaca tctttctttg tcactttctt tacattttca ataacgtcat 17161 cgggagtgtc gtcggtttcc gctatatact ggctgagata aaaatccaca atctgaagct 17221 ggctgtcctt taaggacttg attcctgttt ctatgctttt gatggacgct tcatattcgt 17281 aatcggaaat attgccgttt ttaatctcat ccagttgttt gtatattatc tccaatgcct 17341 tgtctttgtt ttttatttca atcccgcagc ttaccaccat cagtcctttg aatttttcaa 17401 gccttgaaaa cgcataatac gcaagtcctg ccttttctct cacattctga aaaagctttg 17461 aatgaagtcc gccgcctaaa atgctgttgt agaccaaaag tttataatag tccttgctcc 17521 cgggcggtgt attggttcga aagcccaggc acagttttcc ctgatttacg ctcactcttt 17581 caattatgtt tctaacctct cccgtattga cttccacttt ggtcttagcg agggatttaa 17641 cgtttcccct ttttattttt gcaagaccgt ctgttatgta ttttatccct tcatcatcaa 17701 catcaccgga aatgaaaaca tacacaggca gagtttcaag gaagtatttg tagtgttcat 17761 agaggttctt ctcgtcaatc cccctcaaat cctctacgct tccatagtca tatatcccaa 17821 aaggctcatc tttgcacatc tcttcgagac acttttctat gacatactgc attttgtcgt 17881 tgaccctgct ttcaataagc tctttcaaat tctggacttc ctgctccaca tactcctttt 17941 tgaaagcatt gttttcaaga acaggtcttg ttattatgtt taaaagaaga tcaaagtttt 18001 tctttgtgag atcaatatcg ggctgagcat acttgttgga aatatattca acataaaact 18061 gaataatctg atgctctccc ttctttgtca caccgcagtc aaacacggaa ccgtaaagct 18121 cttcaagata aagtgagata tcccttattg tgggataacc ttcacatcct cttcttaaaa 18181 cagcgggaat cattgcattc ttggttgcat tttccctggt taaatcgtca tagaaaaaaa 18241 tattaattga atttgtctta aattttttgc ttttaatagt ataaatcttt attccgttaa 18301 aagatgcaac ttcagatact ttgttttctg aaatcacagt atccattaaa tcaatcctct 18361 ctttgcttat gatgtctttt aaaataatgt atgttaatag tataataaaa aaatgcacct 18421 ttattcaata tttgtaagta aagttctatt agttgtttat tattagtaaa ataaaaacct 18481 tgggcattga aaataataat ccttggaggg attttaatga atcaggtcag atattacaga 18541 aaataccaaa ggacccattc aaaacaaaat gaacaaaata ttgcgccgac aattgatttg 18601 agtattgccc aagccgcagg aatacttgca ctggcatttg caacaggaat cttgtcagga 18661 tgtttgctaa aaaggcttag ataaacaggg aggcatctta acctcccttt cactccgctt 18721 acaaattcaa tcaggccaaa tcctccgcca aaactttttt ggcaatttct atatccttgt 18781 gtatttgctc tataagttct tctacactgc caaacctcat ttcctccctt attttagaaa 18841 tgaagaatac ttctatttct tttccgtaaa tatccttttc aaaatcaaat atgtacgttt 18901 caacggaaat tctgtccact cctccaaatg tagggttgtt acccacattt gtaatgctat 18961 gatacatttt gccgtcaaca agggtccttg ttatgtacac tccatgacac ggaagcacaa 19021 gataatcctc cggataaata ttggcagtgg gaaatccaat ggtattccct actcttctgc 19081 ctttttcaac ctttccggca acggaatagt gtcttcccaa aaatgcaaac accctctcca 19141 tgtcaccttc taaaatataa ttccttattt tagtgctgct taccacttca tctcccagca 19201 taaccggctc aataacaatg accctaaagc cgtattttct tcccagcttt cttaacagtt 19261 cagtgtcacc catgccccgg taaccaaatc tataattaaa gcctgccacc gcaagcttca 19321 tattcagcct ttccacaaga atgtctttta caaaatcttc aggcctcatt cttgagaagg 19381 tttcatcaaa tttttcaaaa tataaatagt caagccgggt tttttcaagt aattccactt 19441 ttttgcgcgt tgaagtaatc aacggagtaa acagctcttt tctgattata ttctccgggt 19501 gcttgctaaa ggtgtacaca accgaatcca aagaattgga ctccgattcc tttattaact 19561 tgtctatcaa agccatatgc cctacatgca gaccatcaaa atttccaagt cctacacctg 19621 tcgatcttgt aaaattgtaa ttactctctg ctccatatat aactctcata tgctttcctt 19681 ctacaactcc gataaaataa ctacttttaa acttttaaaa taactacttt tttgcttata 19741 caaaaagctt gtcaatttta agactcaact cttcactttt gttcaaaacc gcttccccca 19801 aagccagaaa agcaccgtcc ttatcatata ctctgacttt ttgggtcaaa gcaaacttac 19861 cgtattttcc gagagttaca aatcccccgt tcaaaaatct ctttttatcc ttttcattaa 19921 gataaatttt atcataatcg ctaaaaactt tatcaatact tgtcagaatc tcttcagggt 19981 ttcctttctc ggctgtttct tttatctctt ccagagtcaa agcattttta atgtcaaaac 20041 ttcccgattt cagccttacc agaaaaccca tatgtcctcc gcagcctaat ttgtctccga 20101 catcggaaca taaagttctt atataagtgc ctttggaaca tcccacgtca aaaacaactc 20161 tgttgcctcg gatacttaaa atattaataa aatgtatttt aacctttctt ggagtccgtt 20221 ccacttcaat gccgcttctg gcaagctcat acagcttctt cccgttcatc ttgactgccg 20281 aatacatggg aggaagctga ctgtagtccc cttcaaaaga cttaattacc ttttcaatat 20341 cttcaacgga agcctttact tcctgctctc ttataacttc tccataagaa tcctgggtat 20401 cagtggatac acccagcaaa agctccgctc tgtaaacttt gtctttatcc gaaagatatt 20461 caattgcttt tgtagccttg cctgtacaaa caggaagcac acctgccgca ccggggtcaa 20521 gcgtgcctgt gtgtccgatt ttttttattt tcaggattcc cctaaggtat gccaccacat 20581 caaaggaagt catacccggt ggttttaaaa cattcaatat tccgttcata acctacaaga 20641 cttcactaat ctcctttatg agcatttctt ttacatcatt tatatcgcct tttatcgtgc 20701 atccggccgc tcttttgtgc ccgccgccgg aatgcctgtt tgcaatagct gaaacatcaa 20761 cataattttt tgatctgaag tttattttaa gctcaccgcc cggccgctct ctgattgcca 20821 ctgctacttc cacgccttct atgtttcttc ctatattgac gataccttca caatcctctt 20881 cttttgctcc cacacttctt agcaagtcgt cggtaatttt tatcaccgcg agcttcccgt 20941 tttcaaaaag ttcaagattt tcaatggctt tccccatcag cttcaccttg ggcaaggata 21001 cggtttcaaa tacagtttgg gatatatagg aaacatccac gccgttgttt atcaaatcag 21061 cggttatctg gtgggtaacg gtcgttgtat tgccgtacct gaacccacct gtatctgtag 21121 ctattgcaac ataaaggcat gtggccatat ccctgtccag gttgatctcc atctttttaa 21181 gaagccggta tatcatttca ccgaccgccg ctgagtttgt attcactaaa tttaattggg 21241 caaaatacgt atttgtaggg tggtggtcta tattaacggt catgtcggca tcgttaaata 21301 tctccaccct ttttcccagc cgctgcaaat caccggtatc caaggctatt acaagctcgt 21361 atttatccgg tttttcgtca tatatcctta caaactcccg gcccggcaaa aaaccgtata 21421 tagaaggtat gtcttcttca aagtaaataa ttggtttttt attcaacgta tttagtgcca 21481 atgccagcgc cagacttgag cccaaagcat ctccgtccgc tgaaacatgt ggcaaaatag 21541 caattttatt ggctttggta attaaagaaa taatctcatt ttcaatcatt acatacctct 21601 caaaagttaa tttgaatttt ataggattca gcaaattgct caagtatctt cagggtcttt 21661 tgacccctta ttttgagctg atgtttcatt aatcagcttt gtaatataag ctcccctctc 21721 aatggaattg tcaagttcaa aatggatctc cggagtatac cttaactgta ccctgcgacc 21781 gatttcacgt ctgataaaac cggctgcgct cttaagaccc tccaatgaat ttgctttttc 21841 ttctttgctt cccataacac tgacataaac tttcgcatat cgaaggtctt ttgtaacatt 21901 tacctcagtt atgcttatga gtttggaaag cctggggtct ttcaactcgt tttgaattat 21961 atcactaatt tcccttttta tttcttccga tatacgttct attctttcca ttgccaacac 22021 tcctacaact taattgaatg ttgtatttct atgcaaatca gcagaatcac ctttttactc 22081 ttttacttct tccataacat agacttcaac tacgtctccc tcttttatat cattgaactt 22141 ttctatagac aatccgcatt catacccttc cgcaacttct ctcacatcat ctttaaatct 22201 ctttaatgaa ccaagcttgc cttcatgaac tactattccg tcccttacaa gtctgatatt 22261 ggcatttctt gtaatctttc cgtcagttac atagccgccg ccaaccgttc ctacaccgga 22321 aactttgaat atctgcctta tttcaacatg tccgattaca acttccttgt aagttggttc 22381 aagcattcct ttcatagcgg cttcaatatc ctcaattgca ttgtatataa ttgtgtaaag 22441 ccttaaatca acccctgctt tctttgccgc atcaataacg ttggccggag gtcttacatt 22501 gaatccgatt ataatggcgt tggacacctg tgccaaagta acgtcggttt cggttaccga 22561 acctactcct ccgtgaataa tttttactct gacttcatca ttgctaagct tctccaaaga 22621 ctgtttcaaa gcctcaacgg aaccttgaac atcggctttt acaatgatat tcagttcttt 22681 taccttaccc tcttttatct gattgaacag atcatcgaga gtaactcttg cgctggcttt 22741 aagcagctgt tctctttgtt ttagttttct cttttctatt aattgttttg cagttttttc 22801 gtcggttatc acatagaatg tttccccagc ttcgggaact tcatgcaatc caagaatctc 22861 aaccggtgtt gaaggtccgg cctttttgat tctgtggcct ttatcgtccg tcattgccct 22921 tattcttccg gtagtggtgc cgactataat ggaatcacca acacataatg ttcccctctg 22981 tacaagcacc gttacaacag gccctttatc tttgtcaagt tttgcctcaa taacggtacc 23041 ttttgcctgt ttgttcggat ttgccttaag ctccagcata tccgcagcca aaagaatcat 23101 ttccagcaga tagtcgatat taactccttt ttttgcagaa acttcaacaa aaattgtatc 23161 gccgccccat tcctcaggaa tgagtccata ttctgtcaat tcctgcttga ctttttccgg 23221 gtttgcagtc ggcttgtcaa ttttgttaat tgcaacaatg atcgtaacat ttgcggcctt 23281 tgcatggttt attgcctcga ttgtctgagg catgacaccg tcatccgcgg ccacaaccaa 23341 aacggcaatg tcagtaacct gggcacctct tgctctcatg gccgtaaaag cttcgtgacc 23401 cggagtatcg aggaacgtaa tatttctgtt atttattttc accatgtaag cacctatatg 23461 ctgagttatt ccaccggctt ctttttccgt aacatttgtt ttcttgattg catccagaag 23521 cgatgttttt ccgtggtcaa catgtcccat aacaaccacc acaggaggtc ttggcaccgc 23581 ctcaggatcg ttcggatcat cggaatcgtc aaagaggata tcctcctcgc ttacaacaac 23641 ttcctcttcc gccttcaccc caaattcgtc cgcaactata gccgccgtat caaaatccag 23701 ttcctgattt aacgttgcca tgattcccaa agacattagt ttctttatta cttcagctga 23761 tgtcttttta agagcttctg ccaattcctt gacagtaatg ggcgcggcaa tttttattga 23821 cgtaaccaca ggctttggcg gagccggttt ttcctctttt ttctcttctt tcttcttttt 23881 tatcttcctg cttttctttg aaccaccgaa gtaaaaatca tccatctcaa aatcatcgga 23941 taatacttcg gaaactcctt ttctggaatt aaaaacattt tttattactt tgtgattttt 24001 atttcttcct ccgctgattg cggatctcgg ctgttccttt ctaagctccc gcttggagtc 24061 tttttcggca tctttattgt actcacgtct ttcggcacgc tgtgagttaa actcttcttt 24121 ttgggaagtg gtaagttcaa cctttggtat ttccaaagac ttctttgatc cagtacgacc 24181 ttcctcccga tttttatcgg cagcggcttt gctattctgc ttgtttgcat cctgcgggcg 24241 attggaatca tttttcttca tatcagggct tctatgttca tttttctttg cattgccacc 24301 tttgttgtca tttttttcat tcttttttgc ctcgtttttc ttttcagcat tcttttttgc 24361 ttcattcttt ttattattat ttttcttatc catatctttt ttatttaaag tgtccgcagc 24421 attttcctca ttgtttaccg cactgttatc cgttgaaacc tgcctgttgt catttgtttt 24481 tttatctttg tcaatgcttt cattcaaatt aacattggta gcgctatccg ccacggtagc 24541 ttttacttct tctaacactt tgccttccat attcacagag ccatccttaa tttcagcagt 24601 ttgttttgaa ccttcctctt tttttacaac ttcttttaca ctgttttttt cagcatcctt 24661 tttctcattg gtttgagctt ttgatgcttc actttttttc tgttcttcaa gaatcctcat 24721 atattccggc ttcgtttccc ttacgagacc gggtcttaaa cccgaagtct cagtctcaac 24781 tctgacaaaa tcatttttct tacgtttctc ttcgggcttc ttttgactct tggcatcatt 24841 tgccttaatt tcctttattt cctcatcttt tgaatcaaga tagatttccg ttgttctaat 24901 aatcctcggc gctttttttg cttctttttt gagctctttc atggcctcgc tgctatgttg 24961 ggctactgaa tgagctgaag cagttttatt atcatccgta ttggatttgt catctttatg 25021 tctgataacg cctatatggt catataaagc ttccagttca tcctcctcta aaaagctcat 25081 gtgattcttg acgactatat ttatttcttc cagtttttcc atcagtcgct tacttgtcgt 25141 gttaagttcc ttggcaagct cataaactct cttttttgcc aatagcttca cccccgcatc 25201 cgatttttgc ttcatcaatc aactctattg tcctttttgc aaatcccctg tcaagtaccg 25261 ctatcaccga ccttatatct ttaccgataa atttacccaa caactctttt ttaccgaata 25321 ttcttatatc cacttttctg taattgcagg catcaataaa ctttttcttt gtattttgcg 25381 aagcgtcctc agccacaatt accaactctg cttttcctgc ttttagcaat ctttcacatg 25441 actcataacc tgccgccagc ttgtttgctt ttctggccaa tcccaaaaaa gagtatattc 25501 tattctccag catggccctc ctccaattct tttcgcagta attcatatat ctcttcacca 25561 atggatgtct cgaaggccct ttcaaatttt ctaccctttt tggctttctc aaaacaggaa 25621 acatttttgc agatgtatgc tcctcttccg ggttttttcc cggtaaaatc caaagagatt 25681 tcattctctt tgtttttaac aactctgata agttcttttt tgggtttcat ttcctggcaa 25741 ccaaggcaca ttctcatcgg aatctttttt tgtttcatct tccatcactt cccaaaattc 25801 aagcttaaaa catgccgcac cataaagatg tccacatttt ttctttagtc atattttcaa 25861 ttatacatca tccatggtat cttccaccac atcgtcagct gcgttttcag cattatcatc 25921 caccgtatca ttgctgcttt cttcgacatt tgtcttaaaa agttgatccg gtgtaattgg 25981 cgtatcttgc ttttcagtac tgtagctccc gttaaaattc aaaagttgct gctcaattgc 26041 agcccgaagc tgtgattcgc tctttatatc aattttccag ccggtcagtt ttgcagcaag 26101 tctggcattc tgtccctctt tgcctattgc cagagaaagc tgaaaatcag gaacagtgac 26161 cttggcactc ttttcttctt catttatgtc cacccttata accttggcgg gactaaggct 26221 gctggaaata tattcttcag gattgctgct ccattttatt atatctattt tttcaccccg 26281 aagttcatca acaacggcct ggactctggt acctttttga ccgacacatg ctcccaccgg 26341 gtccacattt tcatctttcg aataaacggc aatcttggtt ctcgaacccg gttctctggc 26401 aatactcttt atttcaacaa ttccttcgta tatttcaggc acctcaagtt caaacagcct 26461 tttaataatt ccgggatgtg tccttgatac caaaatttga ggccctttgg tggtcttttt 26521 cacttcaatt atatacgttt ttattctgtc attaaactta tattcctctc ccggtatttg 26581 ttcggaagga gccagtatag cctccgcttt tccaaggtca ataattacgt tttttctctc 26641 tatcctttga acaactccgg taacaatttc tccctcttta ttcgagaact cgttataaat 26701 aattcctctt tccgcttccc tgatacgctg cacaaccacc tgtttggcag tctgagcggc 26761 aatccttcca aactttcttg gtgttacctc tatttcaaca atatcatttt cttcaaagtc 26821 cggatttatt tttttggcat tttcaataga gatttccaac aactcatttt gaggattggc 26881 agtaaccttt tttaaggcat aaaccttaaa atccccagtc tcacgatcaa tcgacacctt 26941 gacattctga gatgagccaa agcttctctt gtaagctgaa ataagagcag cctcaatagc 27001 ctcaatcagt gtatccttgt caataccctt ctctttttcc aattgttcca atgcatgaat 27061 taaatccgca ctcattttag agcctcctta tttactttcc atgtttataa tatcaaaaat 27121 catcactcaa aattttcctg ttttaaatct taccagctta atttaaaact ttatgactct 27181 tctcaccagg gcaaccttgt cccgctcaaa ttccatgagc tcattgccat tcttttttat 27241 aataatcttg ttgtccttgt atcccacaag ttcaccttca aatatttttt tcccttcaat 27301 gggcttaaaa accttgactt caaccagttc acctttaaac cgctcaaaat ccgattcttt 27361 tttcagcggc ctgtcaagtc cgggtgaaga tacctccaaa aagtaactgt gaggtatggg 27421 atcttcttta tccagtatat cacttatttc ctcgcttaca acctggcagt cgtctatagt 27481 tattccgccc ggtttgtcaa tatatatacg cagataccaa cttgagcctt cttttataaa 27541 ttcaacatcc accaattcaa aagagtgctt gtttactacc ggatttgcaa tttccgtaac 27601 aatttcttct atttccttcc tagtcataca aacctccgca aaattaggtt ttttgcatat 27661 cttataccgt gcttatcctt attattataa cttagaattc ccttttcttt cgtgcaattt 27721 tacctgcagc gttcaatttt ttgtttctag tgaaagaaat aataggaaag agtgggtccg 27781 acccactctt taccataagc tactatttgc tttagtccaa aagtattata ccattattat 27841 ttgtaattat caacatttta ttagcattaa ttataattat tattcaaatt tcatagattc 27901 ccaaaaatct cttcagtatt tttgcgttat tttcacaggc ttttaagctg tcaatttcaa 27961 agcaatcagc ataaaacatc agccaaacaa gcttatctgg ttactttcag gtaaaccatc 28021 caggcacccg ttttgctgca aaatttctat aaccgtcttg ctcaccttcg cccttattct 28081 caagtcgtcc acagataaaa actcaccctg gtttcttgct tcggctatac tgtgtgcagc 28141 agaaactcca agcccctgaa gagcattcaa aggcggtctg agtccgtctt tttcaatctt 28201 aaacttaacg gcatcggatt tatagatgtc aatgggcaaa aactttatac cccttgcata 28261 catttcgttt gcaacctcaa gtatggtaag agtgttcttt tctttctggg tcatattgtt 28321 tccttttaac tcatactcct ttattttgtt ttttaccttt tccttcccgt gacacatcat 28381 ggaagcgtca aattcatccg cccttacggt aaaatatgtg gcataaaatg cttcgggata 28441 gtaaacctta aaccacgcaa ttctgaaagc catcataacg tatgctgccg catgggcttt 28501 cgggaacatg tattttattt ttttacagga ttcaatgtac cagtccggca cttttttttc 28561 tctcattatc tgctcatatt cctctttaag tccctttcct tttcttacat cttccataat 28621 tttaaacgct gttttgttcg gaaggccgta gtgtatgaga tttaacatta tatcgtctct 28681 ggtacatata acttccgaca atgaggcaat attatttctt accagatcct gggcgttgtt 28741 gagccagaca tccgttccgt gggaaagtcc cgaaatcctt ataagctcgg agaaagtttt 28801 tggtttggta tctacaagca tctgccttac aaacttggtt ccaaattcgg gaatcgcaaa 28861 agttcctacc gggcagttta tgtcttcggg ccttattccc aaaggttcgg tgctgctgaa 28921 tatacccatt gttctctttt cacctatggg aatcgtcctg gcattaaccc ctgtcaaatc 28981 ctccagcatc tttataaccg tagggtcatc atgtccgagt atgtcaagct ttaaaagtct 29041 tccactgatg gagtggtaat caaagtgggt cgtaatggta cccgagtccg ggtcgtccgc 29101 cggatactgt atcggacaaa attcataaat ttccctgtcc tggggaacaa tcataactcc 29161 tccggggtgc tgtccggtag ttctctttac accggtacaa cctttgacaa gacggttaat 29221 ttccgcattg gtcgcaacta tccctctttc gtcaagatag ttttttacaa atccataggc 29281 cgtcttttct gcaattgtac caattgtacc ggctctgtag acatgtccca caccaaaaag 29341 ttcttcggta tatttatgag ctatcggctg gtattctcct gaaaagttaa ggtcaatatc 29401 aggctcttta tctccttcaa atcccaaaaa ggtttcaaag ggaatatcgt aaccgtcttt 29461 ttttaaaatt ttcccgcacc tgggacattc cttttccggc atgtcaaagc cacacccgta 29521 gcttccgtct tcaataaact ccgagtattt gcagttttcg catatgtaat ggggcggaag 29581 ggaattaacc tctgttatgc ctatgagata ggcaacaaag gatgatccga cggatcccct 29641 cgaccctaca agatagccgt cacttaaaga tttccataca agtttttgcg caataatata 29701 cataacggag aagccatttt ttattattga gttaagctcc ttttccatgc gcttttccac 29761 aatctcagga agagggtcgc cataaatttc tctcgccttg ttttcggcaa gcatccttat 29821 ttcttcttcc gcaccttcaa ttttaggagg aaaagttcct tccggtatgg gaagtatgtc 29881 ctcgcacata tccgcaatta aatttgtatt tgttacaacc acttcatagc atttttccct 29941 gcccagatat tcaaactctt ccagcatttc atcagtggtc ctgaaataca acggtgcctg 30001 gttgtccgca tcggaaaaac cttgccccgc cataagtatt cttctgaaaa cttcgtcctg 30061 cggatccatg aaatgaacat cgcaggtagc gaccaccggc ttgttgtact tctcacccaa 30121 agctactatt tttctgttta tattctttaa gtcttcctca ctgttcacct ttccgctctc 30181 gacaaggaaa cggttgttgc ccaaaggctg tatttcaaga taatcgtaaa actttacaat 30241 ccttgaaatt tcgtcctcat ctttgttttc aagaatcgca cggtaaagct ctcccgcttc 30301 acacgcactt cccaaaatga gtccttctct gtgcatcatt aaaagctttc ttggaagtct 30361 cggccttttg tgaaaatact ccaaatgagt cttggacaca atcttgtaca gatttctaag 30421 gcctacgtaa ttttttacaa gtataatggc atggtatgaa tttgctttct gataattcca 30481 acaaccctca aaaacatttt gtatgtcatc aattgttttt acattctttt cagccagtat 30541 ctcaaggcat ttgataaaga tctccccaca ggcctttgca tcgtcaagag ccctgtgatg 30601 gttttccaat gaaacaccaa gatgctttgc aaccacatcc agtttgtgtt ttttaagctc 30661 cggaaacatt tgccttgaaa gttccaaagt gtcaattaca ggattgtcca cattcctgtt 30721 tataagccgg gcattatgcc tgataaatcc tgtatcaaaa accgcattat gggcaactaa 30781 aggagaagtt cccacaaact ctaaaaattc aggcaaaacc ttgtctatgg ttggagcgtc 30841 tgacaccata tcgtcagtga ttcctgtcaa cttgacaaca aactccggta tcggaatttc 30901 aggattaaca aatgtgctga aggtatcaac aattttacct tccttaatct ttaccgcacc 30961 aatttccgtt attttatctt tatcagccga aaggccggtc gtttcaatat caaataccac 31021 aaactccccg tcaacgggat gtccattggc atgatagaca atgggaacgg aatcatcaag 31081 aagatatgcc tctattccgt aaataacctt tattttattc tttttggccg cctcacaggc 31141 ctcgggataa gcctgtacaa ccccgtggtc ggtaacggca attgccttgt gaccccactg 31201 ggcagcacgc tttatcagtt ctccgaccga cgtaacaccg tccattgcac tcatctgggt 31261 gtggaggtga agctcaactc tcttttcggc ggcattatcg gtcctcacct gcacgggaac 31321 ctcaacaata tctgaagcca atatcgacag ttctcttgag aatttatcgt attgggcttc 31381 accgcgaatt tttacgttgg ccttttcctt aagtctttct ataacacttc cggacttgtc 31441 cttgtccaaa aaaatcttaa cagtaagaga attggtaaaa tctgtcacgt caaatacata 31501 cagcagttta ccgcttttca attcccttgc ttctgtcctt attatttctc cctttacaac 31561 aaccctgcca gaatcctgag tcacctcaga catgttcatt acgctgtcat taaagttctt 31621 gccaaaaata acctcggact tttccccacc ggccgaagat acattgcttt ttgattcccc 31681 ggacgttttt tcacttttct cagttttttg agttttttca ttattcttaa taacagtatc 31741 cgttacaatc ttggcttcct cattttcctt aaattcgata tattcgttta ttttatcctc 31801 atctatttca aaatccttaa attcaacctt tatttccaat ccaaaacatt cttttattat 31861 attttcaatc aaagtatcgc aacttttgca ctttaaaatc tctgttccct ttgtcttaag 31921 gtaaatatat aattttttat cctctatctt ccacttgcat ccgcttaata ttcccctgca 31981 taacgcaata ttcttcttca caatataaag tatgctgtcc caatactttt caagtgcctc 32041 ttctatcgag agctccacat tgaaggaaac cctgagatga acctgctcca gttcgaacag 32101 ttttttaaag ctctgttcaa cactgtcgag ggtctttgca ggtattaatg tgtcagaaac 32161 aataaaaatc tccagtttcc tggatttttt ataaacattt atattttgta ttcttgcagt 32221 gtcaaaaagc tccctctcat tttcattatt aattacttcc ggaaaaagtt cggagagctt 32281 tctttccttt accaacacac tctgcataaa tcccaccccc ttttttacat tctcagtatt 32341 tcctccataa gttcttccac tgccctttcc tgggggatct tacggactat aactcccttt 32401 ttaaacaaca atacttcacc ttttcccccg gcaatgccaa tatccgcttc cttagcttca 32461 cccggtccgt ttacggcaca acccataatt gccactttga tatttttatc aagaccttca 32521 agcctttctt ccactttttc agctattcca atcaagtcaa tctgacatct tccgcatgta 32581 gggcaggaaa caagctcaat cccgcctttt tcaataccta aagcccttaa cagctcatgt 32641 ccgaccaaaa cctcttcctt tggatccccg gtaagcgata ctcttattgt gtctcctatg 32701 ccttcagcca aaaggcagcc taatccggca caggatttaa tggtgccttt aaacacggtt 32761 cccgcttcgg taacaccgat atgcaaagga taatcggttt tttcagacat caggcggtaa 32821 gccgctatgg tcattggaac acttgaagcc tttagggaaa ttacgatatc gtaaaaatcc 32881 aattcctcca atattcgaac atgctgcagc gcactttcca ccatcgcctc aggagttatt 32941 ccgccgtact tttcaatgac attcttctca agggaaccgg aattcacccc aatgcgaatt 33001 ggtatctgcc tggactttgc aacctcaaca acctttctta ctctttccct gtctcctatg 33061 tttcccggat taagtcttat cttgtctgct ccgttttcca tactggatat ggcaagccga 33121 taatcaaaat gaatatcagc caccagggga atctttatgg acttttttat ctcctttatc 33181 gcctctgccg cctcctggtc cacaacagca acccttataa tgtcacagcc gatatcctca 33241 agcattttta tttgattgac ggtagcctca acgtcccttg tgtcggtatt tgtcatggac 33301 tgaacagtaa tttttgcgtc gccgcctata tatatatctc caactcgcac ctttcttgtt 33361 ttctttcttt tgatgtattc catagccgca actctcttct ttctttttta aaaatcaatt 33421 caagttaaat cagtttattt atctttttat aattaatttt tatatttttt attcatattt 33481 tttaattatt aatcttcctc tttaatctta ctgtatatta aattttactc catatcaatc 33541 ctgcaattct acttttatat cagttctgct cttttgcgca gccaggcttc acaattttta 33601 ttcaattaca aacttatttg attataaatc taattatgtc atttgccatt acaaatattg 33661 aaagacctat taaaataata aatcctattg aagtaataat tgcttccttt tccacaggaa 33721 tcttccttct gcttatcgcc tcaatggcaa gaataagaag cttgcttccg tcaagcgccg 33781 ggaatggtac aaggtttgtc gcaccaattg cggcacttat taaagccgtc cacagaagaa 33841 tgttcagcac cgcatcctta aaggtatcac tttgctgcgc cacatcattc atggtgctca 33901 caattcccac cggacccgtc atctgattta tggatacctg gcccgtcaca agccagtaaa 33961 ggctgtaagg caccatgcgt atgttggagt aggtaaacat cgcaccgttc tttaaaacat 34021 tcagaatatt gccacccttt gcccgggaga aggatattcc aagagaataa ttctccacaa 34081 attgcggtac aacattaaag actatttcat tcccgtctct caaaacagtc accttaaccg 34141 gttggttctt attttcctgt aaaaaattct ttatctcatc aatgctttca acctcaacat 34201 catttaactt cacaatttta tctccgggtt tggcgcccgc tttttccaaa gcaccgccat 34261 aaatcaactc cccaataaca ttggagttct cccccgatgc ggaggaataa tatcccaact 34321 ggtaagtcct ttccacctta ggtttaatat ctttttttat ctcttttccg tttcttacaa 34381 actctattgt ggtttctttc ccttttgata catataaaaa ctggataact tccaacgggt 34441 catatattct ttttccgtcg tagccgacaa taacatctcc ttcccggata cctacattat 34501 aagccggaga atctttctga accaaaccta cggttcttgt ggtataaccc gtcgtataat 34561 acactaccga tattatcaga aacgcggaaa tcaaattggc cagaggtcct gccgccacca 34621 ccgcggcccg cacccagaca ggcttgttgt taaaggctct ctcgctgtcc gactcttctt 34681 cctcaccttc cattttgacg taggcaagta tcggaaacaa acgcaacgta taagccgtct 34741 cgcctattgt gacggaaaac agcttcggac ctacaaagag ggaaaactct tcaactttta 34801 tgcctgacag ttttgcaaca ataaagtgtc ccagttcgtg aataataatg ataaaatcaa 34861 aagccagaat aaccaataaa aatctcataa aaacctcctg aaaagtgaat gtttcaagca 34921 ttattagttt catgcattat taatataaat gctgtttttt aacaaaaccg cttattcaac 34981 tattatgtat atgtacttta aaatatatat acaacatata ttatatatac accaaaataa 35041 tcttgacatt ttctgcgcaa caaaaatatc tatttaacaa tttcttcaac tattttcctt 35101 gcccacaaat cgacatcaat tatatcgtca atgtccggat ccggttttac tgaatgtctt 35161 cccattactt tttctataat ttcggggata tccaaaaacc ttattttctc ctgcaaaaac 35221 aatccaacgg ctttttcatt cgccgcattc agcaccgcag gcatggtacc accggcccgt 35281 aacgcctcaa aagcaagccc aaggcacgga aacgcctcaa ggtcgggagc ttcaaaggtt 35341 agactaccaa tcttgacaat gtcaagcttt gaaaagttgt tttgctttcg gtccggatat 35401 gtcagggcaa actgtatcgg aagcctcata tccggagagc ccagctgggc aattatcgaa 35461 ccgtctttgt attcaaccat tgaatgaatg atactctgcg gatgcaccaa aacctcaata 35521 tcatcctgcg gtatttcaaa aagccagtga gcctcaataa cctccaaacc tttattcatc 35581 atggttgcag aatcaattgt tattttgctg cccatgctcc agttaggatg atttaatgct 35641 tccctgagcg tgacatttcg aagttcttcc ttttttcttc ctctaaaggg gcctcccgac 35701 gcggtcaaaa ttatttttgc cacatctttt ttattattac ccattaaact ctgaaaaaca 35761 gcagaatgtt cactgtccac cggaagaatc ttaacaccca ttctggcagc ctcggacatg 35821 acaatatgcc ccgctgttac aagggtttcc ttgtttgcca gtgctatatt ttttttatgc 35881 tttatggcct ccatggtggg aataaggccg gcaattccga caatagaagt aacaacggtt 35941 tcaacagttt caatagaagc caccatttta aggccttcaa caccgcccac cactttgcag 36001 tcggtatcag aaagcctgtc tcttaaaatt ctcgctctct cttcgtcctt taccgcaact 36061 atcttcggtt gaaactctct ggcctgtttt tcaagcaaat ctatgttttt atttgccgcc 36121 agtccatcaa cctttatatt taaatttctg gccacatcca gggtctgaac acctatggaa 36181 cctgtagagc caagaatcga aatcctgttt accatatttt cctccttatg tccgcaaacg 36241 gggcaaccta gataatccag ctcaaataaa agtataccac aggagccgta aacaatatac 36301 tgtcaaacct gtcaagggct ccgccgtgcc ccggcattat actgccaaaa tccttgacct 36361 ttacataccg cttaattgca gaagcagccc aatcacctat ctgggatata ataccgcaca 36421 aaattcccat aacaaagaaa tggaaatacg gaataaactc aatagagcca ctcttgttta 36481 aatacaaacc gtaaaggaat gtcgccaatg cacatcctat tactccgcca attgccccct 36541 caactgtttt cttaggactt atggccggca taagcttgtg ctttccgaaa aaaagccctg 36601 aaaaatatgc catggtgtcg gtggaaaaag ctccgataaa tatgagccag acaaataaaa 36661 agccgctttt taagttacgg gttaaaacta taaatgacaa taaaaacgtt atataaaaaa 36721 caccgaaaaa agtcagcgaa atatccacaa tattgtattt accatgtaag aaaattataa 36781 aggaaaaaag gactacaatc atggcaaaga cagcaaaaag caatgatttc agggatatta 36841 tctgctgaaa aaaagaattt ttcaacactt cactccagga aagaaacaaa acagcggcac 36901 acgaaatata tcccacagcc tttacaggcc tgtaacctgc atttgtcaaa gatctgaaat 36961 actcatacat ggcaagcatg gaaacaaaaa aaaccgccgt tccaagaacc atctgtcccg 37021 aacatacaac cgcaatcaaa agaatgactc ccactagagc gcttatcact ctggttttta 37081 gcaacttcat atccctccaa atcttctgtt tctcctctga taatccaaaa tagcctctac 37141 tatatgctct ttcttaaaat cgggccagag cacatcagta taccaaagtt ccgtatatgc 37201 cgactgccac agtagaaaat tactcaatct cttttctcct ccgggacgta tcaacaaatc 37261 agggtccggt attttggcag tatacagtct gtcatttaac acttcctcat ttatatcatc 37321 aggtttcaat ttaccttcca aaacttcctt tgccattctt tttgccgcat gcacaatctc 37381 agccctgctg ccgtaattta aagcaatgtt caaaatcaac ccgttgttct ttgaagtaag 37441 ctttgtaacc ctgtcaattt ctttttttat ctcatcgtca aatacactgg tatcacctat 37501 gacctgtatt cgaacatctt tgcctccgat atgagtctca gcatttttca aatagtccaa 37561 aagaagactc atcaaggcat caacttcgct tttcggcctc ttccagtttt ccgttgaaaa 37621 agcatagacg gtcaaatatt ttattccgat ctctccacaa aatgtagtaa tttccttaag 37681 aattttggca ccttccctgt gccccatgga acgtggaaga gctctttttt ttgcccatct 37741 gccatttcca tccattataa tcgcaatatg agtcggtaat ttactataat ctatattacc 37801 ttttttccat tttttcgctt taaatatatt tttccaaaaa cccattataa cctccaaaat 37861 ttcctcacaa aatacttttt ccactgatta ttatatatta tatatataag cattggcaaa 37921 agcaataaat tcatttcacg gtctgaattt taaaacccct ctagtgttag aggggtttac 37981 aaacaataag ttcgatacct tcttcacctt tatcaattgc ctttataacc ctgcaataat 38041 cgtcaatatc ggtaagttca gccttaggcg gagatgtcaa tttaacggaa gcaattttct 38101 ctcctgcgtc gtttaacatg ttccttgcct ctttcaacgt aaaaccaatg acattttcag 38161 ccctcatggc taaacctcta gtatttcctt ctcttttatt tcaattaatt tgtctatttc 38221 cgcaatatat ttgtctgtaa ggttttggat gtccttttcc gcactcttga gatcatcttc 38281 ggtgatttcg ccgttctttt tcatggcttt cattttttca attccgtctc ttcttattga 38341 ccttatggca actttggcgt cctcaccata ttttttcgca agctttgtaa gttcttttct 38401 tctttcctcg gtaagcggcg ggaaaactaa tctaatgacc ttgccgtcat tattcggatt 38461 tataccgata tcggattttt gaatttcctt ttcaatttcc tttaatattt gggcatccca 38521 aggttgaatc actataaccc ttggctccgg tactgaaatg gtaccaagct ggttaatcgg 38581 tgtcggcaca ccataataat caaccgttat cctgtccagt attgccgcat ttgcccttcc 38641 cgccctcaca gtattaagct cgtcttttaa tacactcacg gtttttttca ttttttcttc 38701 aatattttta tactcatcca ttgacatact cctcctctat ttacattact attgtaccga 38761 tcttctcacc catcacagct ttaacaatat ttcccggttc gttgagccca aaaacgatta 38821 tcggaatatt gttgtccttg caaagggaag cagcggttga atccattacc cccagacctt 38881 tattgattac atccataaac gaaagcttat caaatttctt tgcattagga tttatattcg 38941 ggtcactgtc atacacgccg tcaacctttt tggcaagcag tatgacttcc gcgtcaatct 39001 cagcggcacg caaagcagcc gtagtatccg ttgaaaaaaa cgggtttcct gttccacagg 39061 caaaaatcac aatccttttc ttttccaaat gccttacagc ttttctccgt atataaggtt 39121 cggctatctg ccgcatttca atggctgttt gaactcttgt aggcataccc tgggactcaa 39181 gcgcatcctg aagtcccaat gcattgataa ctgttgccaa catgcccata taatccgccg 39241 tggttcggtc cattcctttc ccgcttctac ctctccagaa attcccaccc cctacaacaa 39301 tagcaatttc aactcccaag tcatagactt cttttatgtt tcttgaaatc tcatttatgg 39361 tatcggtatc aagccccagc ttcttttccc ccgccaaggc ctctccgctt attttcaaca 39421 taattctttt atacttcggt ttctgcatta aagataatcc tccgctccta aatgttattc 39481 taacatataa acattataat tggaaacaaa ttttattaaa acaacaataa tccctaaaaa 39541 gggaacatat aaatacttta tatgttccct tcatccatta cccgtcattt agccatttat 39601 ttgtttcata acttcctcgg caaagttttc ttccttcttc tgtatgcctt cgcctctttc 39661 aaatcttaca aatcttctga tgttgatatt ttcacctatg atggctatct tttcgttgag 39721 aagctgttgt accgtcttgt caggatcttt tataaacggc tgttccaaaa ggcatatttc 39781 cttatagaac ttttccagtc ttccttcaac catcttttcg acaatcttct caggttttcc 39841 ttcatttagt gcctgagccc tgagaatctc tttttctttt tcgactcttt cagcaggaac 39901 ttcatctctg cttatgtatt caggcttgct tgccgcaata tgcattgcaa tgtcctttac 39961 aaaagttctg aaatcttcat tttttgcggc aaagtcagtt tccgtgttga tttcaaccag 40021 cacgcctatt ctaccgtcac catgaatata ggcgtccaca acaccttccg ctgcaattct 40081 tccggctttc ttggcagcag ccgccagtcc tctttccctt aaaatttcaa tggctttttc 40141 catatcaccg tttgcctcag taagagcctt tttgcactcc atcatacctg ctccggttct 40201 ttcgcgaagc tccttaacca tttcagcagt aaccattcca aattcctcca aacaatatta 40261 attttttaag ttattagccg attttagaat attattctca tttttgacat tttttaaacc 40321 tgactgtaaa aacttaagaa acactctctg aaattccaca gattttcatc ttaccataaa 40381 gatatctaaa atccgacttc agccaacaag cacgctgaag tcggaaaatt ctcaagcttc 40441 cacagcagtc tcttcctgag ccgtttcttc aacctgttcc tgggcggtac tctcaactga 40501 aagctgttcg ccctgtcttc cttctataat ggcatcggcc atttttgacg caatcaattt 40561 aacagctctg atggcatcgt catttcccgg aattacataa tccacttcat ccgggtcaca 40621 gttggtatca acaattgcga ccacaggtat gccaagcctt ctggcttcaa gaaccgcaat 40681 tctttctttt ctgggatcca ctacaaacaa tgctccggga agttctttca tttctttgat 40741 tccgccaaga tacttttcga gtttttcctt ttcagctcta agttttgtaa cttctttctt 40801 gggcagaacg tcaaaaacgc cttcttcttc catcttggtg agctctttca atctgtttat 40861 tcttcctttg attgttttga aattggtaag cattccgccg agccatcttg cattcacata 40921 gtactgatca gctctttgtg cttcttccct tatggaatcc tgagcctgct tcttggtacc 40981 tacaaacagg actccctggc cgttcattgc cacttctctt aagaaataat aagcctcttc 41041 tacctttttc acagttttct gaaggtctat aatgtatata ccgttcctct ctgtgaaaat 41101 gtattcggcc attttcgggt tccatcttct ggtctggtga ccgaagtgaa cacctgcttc 41161 caataattgt ttcattgaaa taactgacat tcaaaacacc tccgttagtt ttacacctcc 41221 gcaaccttca tctttatggg gaacctttcg gcaccatccc ataaatcaag cttgcgtgcg 41281 tattttccgt ctagtagtat aacacatagt tattgtttta tcaataataa ataaaatttt 41341 ttgacaaaaa taagcttaag ctgaaactat gttttttatt tcagtatttt tcagtattcc 41401 tattttattg acaagacatg atacctattt tacaataata tagttgctat aatagaattt 41461 taaaggttta gagggagatt tttgtggaaa acgctggtga atatatcaga gaaaatatca 41521 gaaatgtcgc tataattgca catgttgatc acgggaaaac aacccttgtg gacgcaatgc 41581 tgaaacaaag cggtatattc agagaaaatg aacaggtcca ggaaagagta atggactcaa 41641 atgatctgga gagagaaaga ggtattacca ttctggcaaa aaacactgcc ataacctata 41701 aaaatatcaa aattaatatt gtggacacac cgggtcacgc tgatttcggc ggcgaagtcg 41761 agcgggttct cgggatggtc gacggtgtcc ttttgttggt tgactccttt gaaggcacaa 41821 tgcctcagac aagattcgta cttagaaaag ctcttcaggc taatttaaaa cccatagtcg 41881 tcataaataa aattgacaga cccgaagcaa gaccggttga agtcgtggat gaggtccttg 41941 agttgttcat cgaacttgga gccgatgatg aacagctcga ttttcctgtt gtatacgctt 42001 ccgcaagaga aggttatgct ctatacaact tgaatgacga tccgaaaaac cttgagccgc 42061 tgtttgaaac cttaataaat cacataccgg ctcccaaagg atttatggac aaacctcttc 42121 agcttttggt atcaaacata gactatgatg attatgttgg aagaatagct gtgggaagaa 42181 ttgaaagagg catgattaaa acaggacaac aggccgcttt gtgcaaaaag gacggaagca 42241 ttgaaaatgt caaaataagc cggctctatg tattcagcgg tcttaaaaga attgaagccg 42301 attctgcaat gatgggagac attgttgcag tctcaggcat cagcaatatt aacatcggtg 42361 agacaatttg taatgttgat gcaccagaac ccttaccttt tattgagata gaagaaccga 42421 caatcaccat gaccttcagc gtaaacaaca gtccttttgc cggtcgggaa ggaacttttg 42481 taacttcaag gcatctaagg gaaagactct ttaaagaact ggaaaccaat gttagcctta 42541 gagtcgaaga aactgattcc cctgactcct ttaaagtatc cggaaggggt gaacttcatc 42601 tttcaatcct gattgaaacc atgagacgtg aaggctacga gtttcaggtt tccaagccca 42661 atgtaatttt gaaggaaatc gacggtgtac tgtgtgaacc tgtggaatat ctgattattg 42721 acgttcctga agagttcatg ggcgttgtca tggaaaaact gggaagccgc aaggccgaaa 42781 tggtaaacat gcattcttcc catcagggat atatgagact ggaatttaaa ataccctcaa 42841 gaggtcttat cgggtacagg tcggaatttt tgactgacac aaagggaaat ggtataatga 42901 atcatatatt ccacggtttt gaacctttca agggagaaat accgaaaagg caaagaggct 42961 caatggttgc atgggaagac ggagaagctg taacgtacgg cctttacaat gcccaggaaa 43021 ggggtacgtt gttcatcacg cccggcacaa aggtatatga aggcatgata gtcggagaaa 43081 attcaaggcc ggaggatatt gtcataaatg tttgcaaaaa gaaacatgtt accaacatga 43141 gagcagccgg ttccgatgaa gctttgaggc ttacgcctcc ggtgatactc agtcttgagc 43201 agtgtctgga gtttatagag gatgacgaac tggtggaagt cacaccaaaa aacatacgac 43261 tgagaaaaaa gattctcgac acggagctta gggcaaaaac aaaggcaaga aaaaaagaac 43321 agccttgatt tatatggtaa cggtataaaa gaatatacaa taaaaggcct gcgttatcgg 43381 atataaaagt ataaataaaa gtataaaaag atataaaata taaaaagtta ttgaatagta 43441 aaaagtatgg taataataag taaataagta tattgggtgg tgggaataat gagcggaaac 43501 ggtgcggcag tatctaaaaa caaaacaaaa aagcgaaaaa acagactcgc gtctttattt 43561 ttgtactttc ttgttttcct tattatattt acagtcagca ccctggcttc ttatacatac 43621 ttcataaatg agaaagaaat caattatgaa gaagttatgg caaaaataga ccccgaaaac 43681 ggtattcagg ttgaaatccc ccggggagcc aatacggacg acattgcaaa catcctcagg 43741 gagcacggag taataaaata tcctttttgg tttaagtttg tttccaaatt caacggctat 43801 gacggccgtt acaaatcagg aaaacatatt gtgaacaaag accttaaata taaagaaatt 43861 atggaaatac tctgcagcaa ccctgttaca accaccgtta ccataatcga gggtaaaaat 43921 acggatcaaa ttgctgatat tctaagcgaa aaaaaggtta tcgacaagga ggcctttctt 43981 gaagcctgca ataccgaaaa atttgattat gaatttttaa aagacattcc ggaaaatcct 44041 caaagagaaa acaaacttga gggatacctt ttcccggata cctatttctt tgacccaaaa 44101 gcaggagaac gggcaataat tgaaaagttt ttagataact ttgatgcaaa attcaagccg 44161 gaattttatg aaagagccaa agagctgaac atgacggtgg acgaggtaat tattcttgcc 44221 tccataatag aaagggaaac agctctcccc gaagaaaggc caattgtttc cagcgtattt 44281 cacaacaggc tgaagtcttc ggaccccaat ctaaaaaagc ttgaatcctg tgccaccgta 44341 caatatgttt tgtacaaaac tcagggaaaa atgaaggaaa agttgtccga cgaggataca 44401 aaaatagacc acccgtacaa cacatacctt tatgaggggc ttccgccggg acccatatgc 44461 tgtcctggtc ttgcctccat agaagctgca ttgtatccgg acgaagaatc agagtatctg 44521 tactttgtgg caaaaggaga cggaagtcac gaattttcaa gaactttggc cgaacatttg 44581 gaagctgtta aaaagtatca atccaattga gcaactataa gtagtttaag taattatgac 44641 taagtgacca tagaaaatga aaaaattatt gtgaggattt tacacaatcc tcacattttt 44701 ataatcccaa taatacaagg aatggataaa aatgatttgt tatgagtata taaatgatta 44761 catcagaaag acaattaaaa aaacgaaggg tttttggcag agctcgaaga gtttgcaaag 44821 gaaaatcatg ttcctatagt acatcctgaa gtagcatcac tccttagagt aataggtctt 44881 actctaagac cctcccgtgt tttggaagtg ggaacggcca taggttattc cgccatcctc 44941 ttctccactt ttttggaacc gggaggaagg attgatacaa tcgacaggta cgagcttatg 45001 ctggaaaaag ccagagccaa tgttaaaaaa gccggacttc aggatgtaat aaacataatc 45061 gaaggtgatg ctctggaagt tcttaaatgt cttgagcaca aatacgacat gatatttttg 45121 gatgccgcca aaggccagta tccggagttt ctcccggaat gtctgaggct tttaagaagc 45181 ggcggtcttc tcatatcaga caatattttg tacaagggaa tggttgcaaa agacgaactt 45241 gtggtaagaa gaaaaaaaac cattgtaaag aggcttagaa actatcttga aaccatttgc 45301 aatacggatg aacttgagac aagcattctg ccggtcggtg acggattggc aataagtttt 45361 aaaaaatagc ttttttccaa aacatgtcca tacggcagaa ttttatcaac aaactaggag 45421 tgaatcatat atgaaaaaag ttgaactgct tgctcccgca ggcaatcttg aaaaacttaa 45481 aatggccgtt ttatatggtg cggacgccgt ttacctgggc ggtgaggaat tcagcctcag 45541 agcttatgcc gagaatttta cattggatga gctgaaagca ggagtggaat ttgcccatag 45601 caaaggaaaa aaagtatatg taaccattaa tatattccct cacaatgatg atttgaagaa 45661 aataccggaa tatataaaag aagttgcagg gatcggagtc gatgccataa tcctctcaga 45721 ccccggcatt ctctccattg tgaaagaaat agctccggat atggaaatac atttaagcac 45781 ccaggccaac aatactaatt ttatgagtgc cagattttgg cacaatcacg gtgtaaaacg 45841 gataatactt gcaagagagc tttcccttga ggaaatccgg gaaataagag aaaaaactcc 45901 tgactctctg gagcttgaag tttttgtcca cggtgccatg tgcatatcct attccggaag 45961 gtgtcttctc agcaattaca tggccggcag ggattccaac aggggactgt gcgcacatcc 46021 atgcaggtgg aaatattact tgatggagga aaaaagaccc ggtgaatact acccggtata 46081 tgaaaatgaa agaggcacat tcattttcaa ctccagggac ctctgtatga ttgagcacat 46141 accggaattg gtggaatccg gagtttccag ctttaaaatt gaaggccgca tgaaaagctc 46201 tttctacgtc gcaacggtcg taaaagcata tcgcgaagca atagatgcct attatgagga 46261 taaagacaac tataaattcg atcccaggct tttggaggaa gtctgcaaag tcagtcacag 46321 ggaattcacc accggctttt tcttcaacaa gcccggcccg aaagaccaga tttacgccac 46381 cagctcatat ataagagagt atgactttgt aggggttgtt caaaaatatg acaaagcaac 46441 aaaaatagca accgtagaac aaagaaaccg catgtacaaa ggtgaggaaa tagaagttgt 46501 aaatcccaaa ggcaattttt ttgttcagaa aattgaatgg atgaaaaatg ccgacggtga 46561 agacatagac gttgcccccc accctcaaat gacggtatat atgccgatga aagaggatgt 46621 ggaagaattt gcaatgctca ggcgaaaaag cagtccaaat aaataaaata agtgaaacaa 46681 gagactgggt tttgcttaaa acgccagaac aaatggttta aaatatcaga cgttaagcat 46741 taagcaagta aacaacatca aaaggaagta aacaatatca agtaatcaga aatattaagt 46801 gattaataaa atacaataaa ttataacgca aaatgctgcc aactgaagtt caataatgag 46861 cttcagtttt tttacaatta gtaattcttc ctaaaaaccg gtataaaccc ccttatatat 46921 ggaaaaatta attaataatc caataaatac aagggggcat tccatgttta tcaaacgaaa 46981 taaaattatt cttgcagttt tcaccctatc aatcatactg cttttttcaa gagtaattta 47041 catacaattt attttaggag aaaagctttt tatacaggca acagctcaaa aagtatccga 47101 acttaccgtc gatgtgccaa gaggaaacat acttgacaga aatcttattc cccttaccaa 47161 cagaaaaaag aaagtggatg tggtaataca accgctttac cttaaggata acagcagcga 47221 tcttcagaag atatcaaaca tattaggact taatttcaat gaaattaaaa gacaggtcga 47281 aataaaaaaa gaacctataa aaatcactat tgatgaaaat aaaaaagaaa cacttataaa 47341 agaaaaagtt cagggaatat cctttataca ttcccttgaa agatatgatg aaaacacact 47401 tgccaagcat gttttaggtt atctgaacaa aatcgacata agaggagaaa caggcattga 47461 aaaagcttat gacagctatc ttaaactaaa ctccaaaagc agtgttgcag ttataaccga 47521 cgccagggac aatcccgtaa aaggccttgg ctatcgattt ataaactcag ctaaaaccgg 47581 caaaatgctc aatgtaaaac tgaccattga ttataacata caaaaaacgg cggaggaagt 47641 catggacaag tataatctta aaggtgccgt tgtaatagaa gaagtcagtt ccggtgacat 47701 tgttgccatg gtaagcaagc cggatttcaa tcccaacgaa atcgaaaaat atcttgacag 47761 ccctgacaat gaattgttta acagggccgt ggcatcctac aatcttggtt ccatattcaa 47821 aattatcgac ctggcatgtg cctacagcaa aaacataaac ccgtcaatgt attatttttg 47881 cccgggatat gttattttgg gagacaaaga attcagatgc tccgcttacg gaaaaggagg 47941 acatggatta atagacctgc atgaagcttt tgcatcctca tgcaatccat attttattga 48001 actggggatt aagattggtc caaataacat aatagaaacc gcaaacaaat ttggcttcgg 48061 gaaaattacc ggtattgact cccaaggcgt tgaagaatca gccggaaatc ttccaaaaac 48121 cgggagtttt acttacggag acacagccaa tatttccata ggccagggag acgtcctggc 48181 aactcccctt caggttgcgg acatggttgc caccattgca aacggtggaa taaaaaataa 48241 tgtaaacatt gttgattcca tagttgacag caaaggaaac accgtcaagg ttataaggaa 48301 ggataaaggc gaaagaatta ttgaaaaaga agtgtgtgat aaaataaagc agcttatgga 48361 ggaagttacg gtcagcggta ccggaaccag agcaaactta agtgaatacg gcggtgccgg 48421 cgggaaaacg ggaagtgccg aaaccggtca attcataaac ggtgaaaaag tggtgcatgc 48481 atggtttgcc ggctattttc cccggctcga cccaaaatat tccgtcgcag tatttattga 48541 agacggaaaa agcggcggag caatagctgc ccctgtcttt gaggaaattg ccaaaaccat 48601 tttgaaaaag ggactctaat ttcttgttgt actggcacct taaacatttt ggctacatat 48661 atttataagg tagccaattt gttggaggtg cccaatcttg ttttatatac taatctcctc 48721 ggtttttgag atactgaata atatattttt tcttctagga tatatttcca atgtaaattc 48781 attcccccag cctttaagcc cggaggaaga acagcactat ctggatcttt tgaaaaaagg 48841 cgatgaagaa gcaagaaaca tacttattga aagaaattta agacttgtgg cccacattgt 48901 aaaaaaatac agttccacta taaatgacag cgatgattta atttcaatcg gaacaatagg 48961 acttataaaa gcaatttcaa ctttcaacca tgaaaaaggt acaaggcttg cgacttatgc 49021 agcgcgatgc atcgaaaacg agattttaat gcatatacgc tccaataaaa agactcaaag 49081 tgaagtttct cttcaggacc ccataggagt tgacagggac ggaaatgaaa tagccctgat 49141 tgacgttatc ggaaacgaat cagaatctgt agttgaagaa gtggaactta aaatgcaagt 49201 caaacgtctc tacaataaaa tgaaagatgt attgaaagct cgggaaaaaa tggtattgga 49261 gctgcgatac gggcttttaa acggcaccgg caagacccag cgggaaatag ccaaaatgtt 49321 gggtatttca agatcttatg tttcaagaat cgaaaaaaaa gcaataaaaa aattgggaaa 49381 agagctcaaa tcagaaagct tcaaataatt atctgagggc atttctgctt ttttactttt 49441 atgcttcacc accttataac gcttcttttc ctttattttt ttataaattc gtttatcagt 49501 tctttgagat tcttatgctt tatcattcct gatattatat ttttgaaaat caatgtcaca 49561 atggggccca aaataaggcc gggcaagcca aagaacttca ttccgaggta catggttatc 49621 aacgtcatca aaggatggag gcctatctgc tctccaacca cttttggctc tatcatttgt 49681 ctgataacaa gcactataac atacaaaatc agcagtgaca ctcccatcct gatgtctttg 49741 gttaaaaact catatatggc ccagggaaca agtactccgc ctgttccaag caccggaaat 49801 gcatctatga agctgataac caatccgagt aaaatgggtc gttttacacc aattattgta 49861 aacccgaggg aaagctcaca aaaagtaatt gtcattagta tcagctgagc tttgacatac 49921 ccgaacaagg ctgtaaacat actgtccttt atatctatta tcttgtttaa taatgcatca 49981 ggcacattat ctttgatata gtcataaatt ctgtccctgt cgctggaaat gaaataagtt 50041 gataaaattg tcacaaatat aaatatcacc atctgaggta tggatattgc agtattgtaa 50101 attcccttca caaaagaatc caccaaacta gaaacggaat ttgaaagact tgaaaccata 50161 tttgaaattt gggcggtaac ctcactcgga agtccaaaat aaatattcaa ccctctgttt 50221 attaaattcg atatgttttg atatgcttct ttccaaaact ccggctgaga acttgaaagg 50281 cttgttattt cattataaag tttggaaaac aacataagca acagtattgc aatcatcgac 50341 aaacccaaaa gcaatgaaac caatgccgca aattttcttc taaactttaa ctttttcata 50401 agaaaccgga ctacaggctc tatcattgaa gatatggcaa aagcaataag aaaaggtgca 50461 aaataaattg caagcctaag tcccagcaat attccaataa ccgtacctcc aaaaataaga 50521 accagtctga taacaagttt tattctttta tccataatta ccttcccatc agaaaaatat 50581 ttaacaaagt tttttaagat tcgaaaaaaa tataacatca ttttgtttat ataatattaa 50641 acaatttaac ataatgcaag ggatatttta ttgacacgca acccatataa ataataaaat 50701 aaaaaagtgc ttgcatctac tggaatctac aagcacttga attgagtgat acgtttgtcg 50761 aatcaataat aaaatacctt attttacatg cgtttgtcaa catatttgca cgttttattt 50821 tacacacact aaaatttgtg tttaacatgt cataacacta taaaatcccg gtaaaacaac 50881 cgcatcacct aagttcgact attgtaactc ccgattcacc ttctccgtac tttccaagcc 50941 tgaaagattt aaccctggaa tctgatttta aaaatttctg tatgccactt ctgagtactc 51001 cggttccctt gccgtgaata atagatacct ccgtaagccc ggaaagataa gcatcatcca 51061 aatacttgtc gacactttca atggcctctt ccaagttgta tccccttaca tcaatttcag 51121 ttgatatgct ttttgctttt gacataccta ttttgccaat tccggaattg cttaacacaa 51181 ttttttgttc gtccaccagt tttaaatttg atatatgaac gtttattttc ataattccgg 51241 cctgaaccac cacttctccg tccttgtccg gaggagtgat aatcgttcct ttctggtcca 51301 aattgacgat tagaacactg tcaccgggct ttaaattctc cgggggtttt accaaagcgt 51361 ttttcggagc aaggggcaat tccagtgttt cctcaatgga atcaaccttt cttttaagct 51421 tgagcctaag ctcttccgcc tccttttgcc tctgcgcgtt atggacttcc tgttcaagcc 51481 tcctcatttt agaaataatc tcttccgcct cttttcttgc ttcaagaaga atttttctcg 51541 cttcagctct tgcttcctgt attaatcttt cccgattttc agcaagcttt cttttttgct 51601 cctccagctc tttttttagc ttttcggctt cgagtcgata gctttcagct ttcatttttt 51661 cattttcgga ctgatttaag tttttctcaa tcgacataag catgtcttca aactttatat 51721 cgtcctgggt taaaaattct ttggccttct caataatgtc atcaaaaagc cccagccttt 51781 ttgatattgc aaaggcgttg ctttttccgg gaactccaat caatagcctg taagtgggcc 51841 ttagtgtctc cacattaaac tcgcagcagg cattttccac aaattttgtg gtaacggcat 51901 acgctttcag ctggctgtaa tgggtggtgg caaccgttgt actgcccttg tttcttaaat 51961 actcaagtat tgacattgca agggcggcac cctcggtagg gtctgttccc gctccaagct 52021 catcaaacag aacaagggaa tcttcatcca catcctttaa tattccaact atattcttca 52081 tatgcgaaga aaaagtacta aggctctgtt cgatactctg ctcatcccct atgtcggcat 52141 agactttttt gaaaatactc attttggttc cctcatttgc cggaatatga agccctgcct 52201 gcgtcataag ggtaaacagg cccacagttt tcaaagtaac cgttttacct ccggtattgg 52261 gtccggtcac tacaagggtg ttgaagtctt ccccgatcca aaaatcgatg ggaacaacgg 52321 tttttttgtc taaaagagga tgtcttccct tttttattaa tattttatgt tcatcgttaa 52381 gtacagggca aacacagtta taatcaaggc tgagccttgc cttggcaaat atgaaatcca 52441 aacggcctaa aattgaaaca ttcgacttta aggaatcaac aattcctctt atctccccgg 52501 tcaattcccc cagtattttc tcaatttcag cctgctcttt aattttaagc tcccgtatgt 52561 ggttgttggc ctccacaacc gccataggct caataaaaat ggtcgccccg ctggcggatg 52621 aatcatgtat aagtccgggt atttcggttc tgtactcctg cttgacaggt attacatatc 52681 tgtctcctct taaagtaact atgggctcct gtatatattt ctgatatctt gacgacctta 52741 tgatatcatt gagcttatct tttattgatt cctgggcatt tcgtatctgc cttcttatgt 52801 tggcaagggt cgggcttgca ttgtcagcta tttcatcctc acttagtatt gacatgtaaa 52861 tcctgtcttc aatccgctta ttggattcaa ggcatcctat aagctcactt acaatattgt 52921 cttcatcggt cttgattctg tcattgctcg catagctttt aagatttctt acagccctta 52981 aaacgtcggc agtttttaaa agctctccag ggtttagaat cgctccgatt tcaactcttt 53041 ttaaactgtc ccgtatatca tgaattcccc ccatgggcgg ggttcccctt cttgcaataa 53101 aagcgacggc gtcactggtt tccttttgtg ccctttcaac cctgttaaga tcagtatctg 53161 gcaccagctt ttccgccagt tcttttccca aagaagatgt tgcaaggctt accagtttgt 53221 caattatttt attaaactcc aatattttaa gtgttttttc gttcatctat cccttacctc 53281 gtacgttttt aatgctttat ttgcaccaaa taattataac ataaatatgt tcttcctgaa 53341 agaaagttat actgtgttcc aattcccaat aaatttcatt ctggactttt gtactcatga 53401 aaactttgcc ttgaataaat aaatattaaa acgaaaaacc tataaatggt taagttttta 53461 cactttttta taaaaacttt aaggaggttt tacaaatgac aaatgaaaaa aagcttgaaa 53521 taataagatc atacattgaa gaaataaaag cttatgaaga aagccaagac ctgcctttta 53581 gcaaaaaaca acatcttaaa agagccaggg aagcatatat gaacttgtac agggatgctg 53641 aaaaagggaa actggaccct gatttgcttc acgaaaacat cacaagtttc atgtatatgt 53701 tgcagtaaaa cctccaaagc caaacaccaa aatgagcttt ttattttcag ctttcacact 53761 tttatgcaat atgtccttcc acatattttt ttaccatttc aactgcatgt tcaatatagt 53821 agggcaacgg ttcattcttc acacctgcaa tttcgatatt gcatctgttc aatggtataa 53881 gtatcttcct tgccggactt tccgctattg cagcggccat caaaggtgta agctccccca 53941 tcatggaatt ggctgaaatt attcctatag gaccgactat aatatccacc ttgggagcat 54001 tgaacactat cgcgttttct cccgacgcac cctcattggc tccggctttc agcataagag 54061 tcgtggcaag tgcatttgta cctaaagcta tgatttgtgt atcttcaggc aattcttttc 54121 tgagtttttc aacaacggct ttgccaatac ctccgccctg tccgtccaca actgctattt 54181 tcataatatc ccctctataa ttataaatca accataaata agtttcacag gaaagaagca 54241 atttataaaa attattttaa gaaatattta tttgtaactt gtaaaaattc gcataaaata 54301 attttatata aaatctcata atttttatat gaagtctcca tcatggaatc ttaattattc 54361 acttaaaaat cttattatga tatgacagca taaattctac ttcaaggaat aaaaaaagca 54421 atactaatct atagaatcga catttagtat tgcaaaaccg gtaattaaag acaaataatt 54481 attaatcaat aaaggtatta atcaataaag gcgtaatcag atattttatc tttaaatttc 54541 actgcataaa aactttttta cttatacatt ttttcaagac tttcaataac ggcatctctc 54601 aacgcttcgg cagctttctg cctgtatgaa tcggttttta attttgcaag ctccgcactg 54661 ttggacatat aacctatttc cgctataacc gcgggcatgt ttgtcgtcct taatactgca 54721 agatttggtc tttgaataac tcccatattc tttgacccca gggtcttgtt caaatttttt 54781 tgcactattt gagcaaattc atatgcggta agatttccct tttttttgcc gctgtcagga 54841 tgatacaaag tcatggaccc tgaagttttg ctgttcccgg cattgttatg aatgctgaca 54901 aacaaatcgg ctttttcttt gttcgcaagg tcagatctag tataaagccc cactgttatg 54961 tctttttccc gggtcatata tgtttttatg ccttcagctt taagcaaggt attcagccgc 55021 ttggcaatat ccaagttcaa atctttttct tttactcctc cgtacacagc gcccgattgg 55081 ctccctccgt gaccggcatc aataacgacc ttgtatgttc tattggattt aagaccgctt 55141 cttgaaggta tttccgccgg tttgtttccg atataagcca tttcgttttt tgcatcccag 55201 cctacattct cgccgaaggt ttcagcaaca aatctcattg gaaccataac tgtgccgttc 55261 acgagaatag gcggagcttc catgtacttt acagaacctc ccgagtgcgc cactttactt 55321 ccaacagtca ttttaacggc cttatttcct ttcaccatct ttacaactcc ggaagaggaa 55381 taccattcgg tggttactcc caaaacttga aaagtagttc tcgccggtac taaaattctt 55441 ccctcgataa ttaccgggtt tcgttcgaga gttaaaacct ttccgttcac agctatcaaa 55501 gcattggaag ttactcccca atatcccgaa taatactggc cgtttgcggc aaagccggga 55561 actgtcatga gtatcacaag gattaataca gttaataaaa ttactggctt tttcacaact 55621 cccctcctct ctttccacag atttaattat atcaggttta cataataatt ctataaaaaa 55681 acacaaactc cctctatgta atttattcta agggaaaata agatatcgga gaaataagtt 55741 gacataaaat ttgtgttttg ggtacgacta cttcagttct taaatttatt tctgattatg 55801 ggaaatatcc aaaaaccaag agacattgaa acaagacatg cagcaattgc cgaaagaatg 55861 ggaagcaaag taaaatacaa ttgtgacagt gaaacaacag tatcgtcgag aacagccaag 55921 gtcattctaa taacacctat gataaacaaa aaggctattc ctgtaatttg aaatatataa 55981 tgctccttta acaggtttaa aacagaagct gacagtaaaa ccacaataaa taccgcaact 56041 gaatatgaaa tagttaaatc cgcattcaag tccaaacacc cattcttaca attttatgaa 56101 tttttaccgt cttatctttt taaccgcaac atatattgta atactcaatt aaaataattt 56161 caaattattt ccctacatac ctcccaaaat aagtttaggc ttcgacaaaa ttaaatttcg 56221 ccaaagccca gataaaacta attaaagctt tttattaaat tatatcagtg tcaaacaaat 56281 tataatcaac taaaaacaaa tttcttttta atttatatat ctctctatct gtccgtcaaa 56341 cagaggatta acccttaact gctccggcag tcataccgct gatgaacttc ttctgcattg 56401 tgaagaacat gatgagtaca ggaatagtaa ctatagtacc ggctgccatc agcaaatcgt 56461 atcttgcagt tgtgtatgca ataaagcctc tgataccggc aggaatagta gtcaccttgg 56521 tatccttgag aagaacccat gcaaaaatca gctcatccca agccgtcagg aaaatgtata 56581 ttgcagtcgc aacaattccc ggaacggcca aaggaagcat taccctcagg aaagctgtaa 56641 atttattgca tccgtctatt ctggcagctt cttcaagctc accgggtatg gacgcaaaga 56701 atcctctgat gatccagata ctgaaaggaa cgaaaaacgc cgaatatact attacaagtc 56761 ctggaatcga gtttatcagc tgtattccgg ttgcttgctt aattttaaca aagtcgagat 56821 aaagaggaag caagaacatc attccaggaa gcaattgcgt tgcaagaata agaataccaa 56881 agaaacctga ccccggaaat ttgtattttg ccaaagagta acctgcaagc gttgcaataa 56941 cgagcgccac aaccataaca attgaacata caataagact gtttctgaaa taaataccga 57001 aaggaagttt ttggaagact tcaacatagt ttgagaatcg agtaggtgca atccatttac 57061 cccttgcaat ggcattatga tccatcaaag atgtcagcac catgaatact atgggtccga 57121 gggttaatac caccaatata gcgagaatta tattggcaat ggtatcctta atttttttct 57181 ttcttttcat cgattcaaaa taacctattt tagccattac ttcaccacca aatcatcttt 57241 aaagagtgta taccataaag caacaatacc aagtacaaag aacattacaa tcattaaagc 57301 cgccgcaccc gggccaaacc tccacatctg gaatgtattt ctctgaatgt atgtcatcag 57361 aagatctccc cattcacccg gtataccggc accattacca aacatcattg aaacaatatt 57421 gaaagaataa atatttgaaa ttaatgagaa cataacattg atggcaagaa taggtttcaa 57481 cagaggcaaa gttatatgcc agaacttctg ccaaccgttg gcaccatcaa tatcagctgc 57541 ttcataataa tccggtgata tactctgcaa accggccagc ataagaatca tagaaagagg 57601 aagacctctc catattgtag gtataattat tgcccaaatc tggttgggcc ctaccagcca 57661 atacggcttt tcgggtaata tatgcagtat gtcacacaaa ataatgttta ttaaacctga 57721 atcctgtctc cataaaaagc cccatgtcat accaacaaca taggaaggta caacccaagg 57781 cataaggagc gcggttctta caatacctct ccctttaaat tccctgttta caagcatagc 57841 cagtataatt cccagggcaa atgttgcaaa agtaactacc accgtataaa tggccgtatt 57901 tctaagagca aaccagaaac ctcttctaat caaactcttt tcatcaaaaa gaatttcata 57961 ataatttttc agacctataa acggtgcatt caaaaactta gtcattgtca actggttaag 58021 atccagcaaa gacatatata ttccctgaag catgggaata aagtgaatgc acatcatgca 58081 aacaaaagta ggtattaaca ttgcatacgc aaataaattc tgctttattg aatataacag 58141 atgatttttt gacttttttt ccttaactcc tataccagat ttctttaatt gtatatccat 58201 ataaccaagc tcccacaatt tttatagcat ttttatactt ataataaaag actataataa 58261 aagtattgag tctgtgcaga gcatttctgc tctgcactaa actcaattaa ctttataaaa 58321 atgtcttttt cagaagaatt attcttagaa attatttgct tgtttcttgc aatatttggt 58381 tgatttgact ttcaacatct tttacgattt gtacagtctt gtcgtagctg tatgcaccat 58441 caacttccat aacgttatcc cagatcttgc tgagaccttc tgagaagata acttctgcag 58501 aagcccaacc aggaactgat gcatagtgtt taccatattt gtctacctgt tctttgaata 58561 ctttcatcaa tgaatcttca aagtatggat cttcgtaagc cgctttaaca accggaagca 58621 tcttgctaac ctttgagtat tcaacctgag cttctttgct agcaaagaac ttgagaagtt 58681 caagggcttc atccttgttc tttgatgagt tgaatattac aaggttactt ccacccatga 58741 atgcatatct tcctgcaggt ccttcaggaa ccatagtaac accaattttg tcgataaggt 58801 cgttaccgtt ttcttcttta ttctttgtgt aagatgaaat aacccaagga cccatgaatg 58861 cagtagcgta tgcaccgtca ccaaatgcgg actcaatgtc acttgtattc ttttcaagtg 58921 aaggctcatc catcaaacct tcaacagcaa gttctgaata gaatttgata cctttaagag 58981 cattttcgct tgagaaagta gcttgtgtac cttcttcgtt tacaaagtct ccgccggcac 59041 cgtaaatcca ccatgagaag ttatgaacaa cgttccagtc gttcttaccc ggcataccca 59101 gtgcagccag tttcttgccg tcaacttcaa taccgttgag tttcttgaga gcatctttga 59161 atttgtccca agttgcgaaa tctgtttcag gatttacacc tgctttttcg caagcgtctt 59221 ttctgtagaa gagagctctt gtttcagtaa accaaggcat accgaacatc ttgtctgtgc 59281 ctttgatata agctgactgc agagttgatt caacgaaagc acttgtatcg atttttccgg 59341 taagctcaac caatgcacct tccattgcac cgatagcagc tgtccaagtg gaaccaacct 59401 gtgtaatgtc aggagcttca ccacttgtag cagcagctgt gatctttgtc aaagctgcac 59461 tccagtcaac aactgtaggt tcaactgtga tatgaggatt agcatctgtg aatggcttaa 59521 caactttcaa aagatcctgg tccggtgtgt cactgttagg catgatccac atggtcaatt 59581 ttactgggtc cttctttgtt cctgaatcag gcgaattttg ggaatcgttt ggttgcggtg 59641 aagtcgtagt atttcctcct ccaccaccac atgctgccag acttaaagcc ataacagcaa 59701 ccaacattaa tgcgattacc ttcttgagca tagttttttt ccccctttaa tgataattaa 59761 gatattgctt atacaataaa ttatattata aattaatcta aaaaaaacaa catgaaataa 59821 ttactatttt tagtgaaaat attacgttac aactcaaatt gcgccgtttt gcttatccta 59881 cgtcagtttt ttagcttatt gtattaattt taccgggagg caaaatatac cgctgcctga 59941 aacatttata gccaatacag ttatcttgcc tgtttcgtcg gctgcaaaat gcattatttg 60001 acgggaattg caacgtggtc ggcatattaa ttcatatgag ctgcatatta attatgtggt 60061 aaactatgtg gtaaactgcc aattttttta gattaatttt ttgtataaac aatatctttt 60121 cactctatta tattatcata ttttacgtat ttattctata attttaatgc atattatttt 60181 atttttatgc atattttttt tgattatgca ctcttcatct ggactaaaaa aatcaacccg 60241 actcactttc atgtatttgt tgttatgtca acaaattttt ataagtaagt tttgttgtta 60301 tgttaacaat ttttttgtaa ataaaaaaca ggcaaagtac ttccataata tagtttatat 60361 ggcagtactt tgcaaaattt tctcaccttc tttgcttaaa aatccgccgg gattacaaaa 60421 taatacaaat aagtcctccg cttccctcgt taattatttt ttgcagtgtc tcctgaagtt 60481 tcagctgtgc gtcttcaggc atcctgtaaa gcttgttttg aagcccttca ctcaccagtt 60541 catgcaatga ctttccaaag atgttcgact gccacaattt ttccggttca ttttcaaatt 60601 cctttaaaag atagctgacc agttcttcgg actgtttttc cgttcccacc aaaggcgcta 60661 tttctgtttc aatatccgcc cttatcatat gtattgaagg cgcacttgcc ctaagtttaa 60721 ccccgaagcg gcttccctgt tttattattt cgggttcttc aagagacatt tcttctatct 60781 ggggagatac tatgccatat cctttaagtt taacctcatg aagggcatat tgaactttat 60841 catattcttt ttttatcctt gcaagctccg tcataagtga aataagcctg tgttcgccgt 60901 caatttcaag cccggtcatt tcgctcaata tacgataaaa cagtccgtcc tgctcattaa 60961 tctccacata agcagttccc gaaccaaggt ttatgtgatc aatataagcc cgttttataa 61021 attcaaattc atcaaacctg tttacactgc ccctaatttc ccggatcctg gtgattcctc 61081 tgaaagcttc tttcacagca ttaattatgt caactttaag ccagtggttg tcatcaaggg 61141 actcaatcca tttcggtatg ttaaccccaa tttcatttat cgggaactca agcagcaccc 61201 tttccattat gttgttcaaa tcttcgattc gaagctgtgc gcagttaaca cctatcaccg 61261 gaacattgta ctttgcctca agttcctgcc ttaaactttc tgtttcagga ttcgacggat 61321 ttatcgaatt caaaagtatt acaaatggct tgttaatctc ttttaattct tttacaactc 61381 tttcttcggc ttcaacgtag tcttccctgg cgatgtcggt tatactgccg tcggttgtaa 61441 ctacaaatcc aatggtggaa tgatcagtga taactttttt ggttccgatt tcagcagcct 61501 gaacaaatgg aatctgctca tcaaaccaag gtgtggacac catccggggc atgtcatttt 61561 ccatgtggcc aatagcgcct tttaccatgt atccgacaca atccaccagt cttaccttaa 61621 agtgaacatt ttcgtcaagt tcaattttaa tggcttcatt tgggacaaat ttcggttcgg 61681 tggtcattat tgtgcgtccc gaagcacttt gcggaagttc gtcttttgcc cttgcccttg 61741 aaaattcatt ttctatattc ggtataacca acaagtccat aaatcttttt atgaatgtgg 61801 actttcctgt tctcaccggg ccaacaacgc ctatatatat atctccctgc gttctttctg 61861 caatttgctg gtatatatta tatttttcca cccgcaaacc ccccttactt ttatttgaaa 61921 cctacttcaa tcaattgttt tccactcgaa actcaaactt aaggctgtaa ccgctttgac 61981 cgcgtttgca atgctgtcgg agcactttac tgtccattgg cttaaagaac gcatcttaag 62041 ttttgagtac tagtattctt atcaatataa atatattgtc tctattcgtt tattattaca 62101 aatatcatta caaaaaagca caaaaaaagt gagcagtttg tcttttccaa atctactcac 62161 ttttcaacac acatttcaac acacaatcag caaaaaaatt tcataaattc tttaattaaa 62221 taaatatttt attttaatca aagccatttg gcatccaatt cttcaacctc atttttcttg 62281 ttcctcatca taagatcata cactgcctgt cttggattct ttccgttaaa caatacttcg 62341 tatgcttcga aggttatggg catcgcaaca tccattttcc gtgcaagttc ataagctgct 62401 tttgtcgttg taacaccctc aacaaccatt ttaacttcat ccattgcttc ctgcggtgat 62461 tttccctgac cgatcaaaat tccggcacgc ctgtttctgc tgtgcatgct ggtacaagtc 62521 acaataaggt ctcctatacc cgtaagtccg gcaaaagtct ggggatttgc ccccatggaa 62581 actcccagcc ttgaaatttc ggttattcct cttgtcataa gcgcagcctt ggtattgtcc 62641 ccaaaaccca aaccatccga tattccggca cacaatgcta ttacattttt caaggcacct 62701 ccaagctcca ctccgacaac atccgtgttg gtgtaaactc taaattccgg tgacatgaat 62761 atatcctgaa taagttccgc cgctttgata tcacaagatg ccgccacaat tgccgtgggc 62821 acacctcttc ccacttcttc ggcatggctt ggacctgaaa ggataacggt ttttgcgtct 62881 tttatctcct gacctattac ctcggacatt ctaagccccg ttccttcctc caaccctttg 62941 gaacaactaa caattaccgt atcatccctt atatatttcg atatatcctt tgcagtctgc 63001 ctgacagttt gggaaggtac caccacaacc acaacctcgg catcacacac agctttttca 63061 agatccgatg taaatgtgac attctccgga acaataacac ccggcaactt atgtacatgc 63121 tctctttttt cgttcagcat cttaatttcg tcttcaaaaa tcgaccacat ggtaacactc 63181 atgccgttgt tggccaataa caccgccaga gcggtccccc agcttcccgc accaattatg 63241 gatatttttt tgttcatagc aagcctcccc ttactcattc ttcttggcac cgagcttatt 63301 ttcagtacct ttgcacaatc ttacaatatt ggagcgatgc ctgattataa caagaagaga 63361 tacaaaaacg gcgaaaacaa tgtatataat atccttttcc ataaaagcga ccaaaaaagg 63421 gaaacacaat gcagccgtta ttgagcctaa agatacatat ctggtcaaca caaccaccac 63481 caaaaataca cccagaagga taagtccctg atacgggcct gcaagcatta tcacggcaaa 63541 agtggtgagc acgccttttc cgcctttaaa cccgaaataa agaggccagt tgtgtcccag 63601 tattgctccc aatcctccgg caagaagtcc ggctctgtca agttctacgg taaaatttaa 63661 ttctgacgaa tcgaaaccaa ttttaaaaat ataataccca ataacacatg ccaaaatccc 63721 ctttagcgta tctcccaaaa ttacaaggaa agccggaaat tttccgagag ttctcaaagt 63781 attggtcata cccgcatttc cgcttccgtg ttttctcaca tccacaccgt aaaatttccc 63841 gacaataagc gaggtattcg cactgcccaa aagatatcct atcaaagcag ccactaccgc 63901 cttcaatacc ggccaaacca atcttatcac tccttttctt tttccctcaa tatgaatttt 63961 ataggcgtac cctcaaatcc aaaactcttt ctaagctggt tttccagata cctctcatac 64021 gagtaatgca taagctccat attgtttata aaaagaacaa atgaaggcgg tttgacagat 64081 gattgagtca tataataaat tttgagtctt ttccctttgt ccgaaggagg ctgcaccatc 64141 gcagtagctt cattcagaag gtcatttaac actccggtgg aaattctcat ggccgcctga 64201 tccgccacat gctttatgag tccgtaaatc ctgtcgactc gctgtcctgt caaagccgat 64261 ataaagatta ccggagcata gagcataaaa cccagttttt catgaaccgt tcttctgtat 64321 tcttcaaggg ttccggtctg tttttcaatc aaatcccact tgttcaccac tataatggaa 64381 gccttgccct gttcgtgagc gtaccccgct atttttgtat cctgctcggt aacaccttct 64441 tttgcgtcta tcaatatcag acaaacatcc gccctctcaa ttgccgtcca ggatcttatg 64501 atactgtatt tttcaatttt ctcattaatt ttgctctgcc ttctgatacc ggcagtatca 64561 ataaaaacaa atttgccgtg ttcattttca acaaaggtgt caatagcatc tctcgttgtt 64621 cccggaatat cgctcacaat tactctttct tctcctaaaa tcctgttgat gagagacgat 64681 tttccgacat ttggctttcc caccaccgca acttttatta catcttcatc ataatcctca 64741 gcatcttctt ccgggaaata tttgaatatc tcatcaagca aatctcccat tcccagtccg 64801 tgaatggaag aaatggccat tagttcacca aaaccaaggt tgtaaaattc gtagaaatcc 64861 gcaggaagtt caccaatttt gtccactttg ttgacagcca ctataacagg ctttttggtt 64921 tttctgagca aagtagccac ttctttgtcc gacgcggtaa ctccatcttt tacatccacc 64981 ataaatataa taatgtcagc cgtctcaatc gctatctcag cctgtctttt catttgctgc 65041 attatcttgt cttcagaata gggttctata ccgcccgtat ctatcaatgt aaactttttg 65101 tttctccatt cgacttccgc atatattctg tcacgggtta cacccggtgt atcttcaaca 65161 atggatattc tttttcccac aagatagtta aaaaaagtcg atttgcccac attaggcctt 65221 cccaccaccg caacaacagg cttcggcaac ttctctccct ccatatgttt caaaatagta 65281 aaacatcaaa ccacactatt ataaaactat tcccagaact ttttcaatga aatcttttcc 65341 attatttcta actattgtta tctttgtttt taatttatct tcgagcattt caacagtata 65401 atcgtcaaga aatactcttt cgccggactt caacatggat tcggaaagca aaagttcccg 65461 gccgagattt tttccggaca gctgcctctc aatgtcctgt cctgtaagaa gtccggtcac 65521 agtaacattt tccccaaaaa aattattctt tattttataa acatgaacat acaaattctt 65581 atatttattt tcaagaatat ctatcatttc ctttatatat ttataagaag aaactccggt 65641 tgctatggaa acttcccttt tattttcgag cttgagctca agttcttcaa agtaatcatc 65701 aaattctttt ttaagcatcg cgacaaggcc tacaccgttt tctatctggg gaaaatcctc 65761 gtaaacacaa taatcgggaa tttcaagccc tgccatgata taaaactcat ccgcaataaa 65821 aacaattctt gaaccgtatt ttgaaagaag ctccatctgc caggcttcaa cctgttttat 65881 aacttccctg gatgattcca tgtcaaaagg ctttaactcg tacaatcctt cacgatactt 65941 tgtgatacct accggaacca cagaaatact gtttaagccc ggataaagtg cactaaggtc 66001 ctttagggtt ctgtcgagtt cctttccgtc gtttactccc cttaccagaa ctatctgtgc 66061 attaaccttt attccacctt ctatcagcct cttaattttg tccattacat ctcccgccgt 66121 cttgttcctc aacatatata ccctcaattc cgggtttgac gtatgaaccg aaacattaat 66181 gggagacatt ttatatttta ttatcctgtc tatatcatca taactcatat tcgtcagtgt 66241 aacataattt cccataaaaa acgaaagcct ggagtcatca tctttaaaat aaagagtctc 66301 tctcattcct ttgggcagct ggtctataaa acaaaaaatg catttatttc tgcagctttt 66361 ggtatcatca atcatcagat tttcaaactc aatacccaaa tcctcatatt cgtccttctc 66421 aatctctatt tcccagattt ctccgttttt cttttgtact tcaaggacaa gattctcgtc 66481 ggcaattaaa aatctataat caaatatgtc acttattttt tggccgttaa tggataatat 66541 caagtcccct tcctgaaggt cagactcttg tgcaatactt ccgggcaaaa ccctttttat 66601 cggtacaggc ctgtatttca atccaaaacc tcccattctt tactaatcgt atgtgcggta 66661 ataacaaaat atactgtaaa acacaccata agcaaaaagc agcagtttgt atctgctgct 66721 tttactctat tctacgctga gaacctcaat tgacttgcgc tcacctttat gccttaccgt 66781 ataatgcccg cactctttgc atactctgtg gagcagcttc aatgagtggc aatgcggaca 66841 ttcaaccaag ttgggtactg ttaacttcca ctgagacctt cttttgcctg ttctggcttt 66901 agaccattta cgctttgggt ttgccatgca tcacacctcc tcgtcaccat acaacaaacc 66961 ttgtgtataa ataaaatctt gtacacatgg aaggtactcg attttgtttt tacttaaaac 67021 aaagctacac taattgtctg taaaaaagtt tttgaaaact tccagccgcg gatctatatc 67081 ctcatttacg catttgcact catcgttgtt aagatccgct ccacacttcg ggcaatatcc 67141 cttgcaggcc tcgtcacaaa cctgctttgc cggaagattc agtatgatat tgtctatcat 67201 taccttttcc agctcgagga acttaccatg gtacgtataa tattcctcgt cggttttgtt 67261 actgccctct tctacaaagt tttcctttac atcaatatgc atctttgatt caatatcctt 67321 gaggcacctt gagcattttg ccctgtaatc cgcccagagt tcaccgtcaa gttttataat 67381 ccctccggca tttaccaaag tgcccttaaa agttaccggt ttcgcaaagt caaaatcctc 67441 agctataaaa tcattaattt taattgactc actaaagtcc agtctcagcg aagctccact 67501 atgtttcaaa atgtcagata tatcaatttt catcaaagtc acctcttaaa accgacaagg 67561 actattatac taactaataa ccctcatgtc aagaattata tgacagattg gcttaaataa 67621 caaaaataat tttgtttagt taaattcgga atttcttctt aatattatta acatattcca 67681 catattaata caagaaaaaa cccggcaaaa aataaaaaaa ttttacaagc ccgtttccta 67741 aaaaaacagg cttgtaaaat tataacgcat cttttataag ttttttacaa gtcttaaagt 67801 ctcccttgca atctcaagct cctcatttgt cgggataacc aaagtcttta ctttcgcatc 67861 gggagcactg atatccgctt ctttgccttt cacttcattt ttatccaaat ctattttaat 67921 tccgaaaaag tccatatcct tcaaaacttc tcttcttata taagcattgt tttcgccgat 67981 acctgcagtg aataccaccg catcaacgcc gttcagcact gcaatatatt ttccaatata 68041 tttcctaaca ccatagcaga aaatatccaa tgccagctgc gccctgtcat ctcccttttc 68101 tgcggcatcc tgaacatctc tgaaatcact gcttacacct gaaattccaa gcacacctga 68161 tttcttgtta aggaaattgt ttatatcgtt aatattcatt ttttcctttt ccatcaaata 68221 agttataacc gcagggtcaa cattgccgct tctggtaccc atgcacaacc cctgcagagg 68281 agtaaatccc attgaggtgt caacggattt tccgcctttt accgcacaaa tactcgctcc 68341 gtttccaaga tggcaggtta tcagcttcag gctctcaata ggtttgccca gcatctgagc 68401 cgccctgtgg gccacatatt tgtgggaagt tccgtggaat ccgtattttc tcaatttata 68461 cttctcatat atctcataag ggagggcata aatatatgca tgccttggca ttgtctgatg 68521 aaaagctgtg tcaaacacag caaccatcgg cacatcgggc agtatctgtt tacaggcttc 68581 aattccgatt atatttgacg gattgtggag cggagccagt tcaacacaat ccctgattgc 68641 tttcattaca tcttcatcaa ttatggcaga ttccttaaac ttctctccgc cgtgaacaat 68701 acgatgaccg acggcagaaa tttccgacat gctttttatg actccgattt tttcatccgt 68761 aagagccgaa attacctcct gtatggcaag cttgtgattg tacaggtctt tttctataac 68821 tacggtttcc cctccggtct ttgtatgctt taaaaaggaa tgttcaagac caattctgtc 68881 acacacacct tttgcaagca cagactcgtt tgtcatgtca atcagctgat actttagtga 68941 tgagcttccg gtattaataa ccaaaatatt catttcaaaa actcactccc gtcttgtttt 69001 tttaattttc ctattcctaa acttcgataa acagatgttt ttattaaacg ctgcgcaaca 69061 ccttcttcaa tgtccggttt taacagaatt tatgccttga catattgagc ctgaaccgca 69121 gtaattgccg caaccccgac tatatcctcg gcactgcagc ctcgtgacag atcatttacc 69181 ggtcttgcca aaccttgtgt tatcgggccg taagcttcag cttttgccaa tctctgtgta 69241 agcttgtatg caatatttcc ggcatcaaga tccgggaaaa taagaacatt ggcctttcct 69301 gcaacactgc ttccctttgc cttcgatttt gccacttccg gaacaatggc ggcatccacc 69361 tgaagttctc cgtcaattgc aaggtgggga gctttttcct ttgcaagctg tgttgccttg 69421 attacctttt cggtcagctc acttttggca ctgccgtaag aagaataaga aagcattgcc 69481 acctgaggtt ttgctccaac cagcatctca aaagatttgg atgcagatat tgcaatttca 69541 gaaagctggt ctgcatccgg attttccacc aagccgcaat cggcatatac aaaggttccg 69601 ttatgaccat attcacagtt gggtacaacc ataacaaaaa aggatgatac gagttttgtc 69661 cccggggccg tctttaatat ctgcaaagcc ggtctcaaag tatttgcagt ggaattgaca 69721 gcacccgcca ccataccatc cgcttcacct ttttttacca tcataactcc ataataaaga 69781 gggtctttga tcgtttccct tgcggcttct atagtcatac ccttcgattt tctaagctca 69841 tacagtgtat ttgcataatc ctccaatttt tcggaattta aggaatcctc tatcatcact 69901 ccttcaagat caatatcccc cgccagactc ttaatctcct tttcattgcc tatcagtaca 69961 acctttgcaa ttcccttttt cactatcatg gatgcggctt taataaccct cagatccgta 70021 ctttccggca aaactatggt ttttacgtct gatttcgccc tttcaattat ttgttccaaa 70081 aaactcataa attcttctcc tttcataatc ccaaaactgt tatcataaaa actgtatttg 70141 taatacttat aactatatat tatcaccagg taataatacc tgctcactat aaacagctat 70201 tttactgggt tccaagcaac tctaattata tacaaaatgt tttttgtata caagaccctc 70261 cttatctttt tttcggcttt agccataaat aacggcaagt aactccaaaa tacaggatat 70321 ttcatgcttt tagaaacttt ttattagtct tcttaattat tcagattttg tggcaattaa 70381 actttgcagc tcctccaaat agttgtccag ctcctcttct ttaagattgc tgagatatga 70441 caatctgtaa tttttagcct ttttggccat ctctagcgca ctctccgtca ttcccaaatc 70501 tttcaaaaca cagctatagt tatagtatgc ctcaggaaaa tttggattaa gacctataag 70561 ctttcgatat atttcctcgg cctttttaat gttaccgatt ttgtaatagg tatagcctaa 70621 attgtcaagt atgacaggat cagagctgtt atactcatac gcctccttat tgaaatttaa 70681 agctttgttc atatccccgt ccagaataag aagatatccg agacttccgt atatggttgt 70741 attcttatag tttgaaaaca catcctccag catttttatg ccatctttca actgtccctt 70801 tttccaaagc accaatgcat agttggactt tgcctgaagc aagccggcat tgtcgatatt 70861 tgagtttaaa agctcttcaa aaaccttttc cgcctcttcc agctttcctg tcttaagaag 70921 caaatatcca tacaaaattt taaccgaagg tctgccttta gcggcactgc aagccttttc 70981 aagccacccg ctcgctctgt ccatatctcc ttttttataa gcacgggtcg caagaacttg 71041 ataaaaaata cttctttggc tgtataaaat ataaatgaga aaagccaaaa aaagtaagta 71101 tccggctgtt ttgtgaacca aaaaagccaa aatgattaag accatacaaa ttgcatattt 71161 gaccggtgta tttttttcca taatcaaacc tcctgcgcca aaggtcctaa aacccgaatt 71221 ttcggcgcct attctaattt ttatattttg tcaagttctt ctttcaaaat cttgtttaaa 71281 agccggggat ttgctttccc cttagtctct ttcatagcct gtcccacaag gaatccgaaa 71341 actttgtcct tgcctttttt gtaatcctcc accaattttg tattgtttga aatcaccttt 71401 ttaacaacct cggcaagagc tttttcatca cttacaactt caagtccttc ttcccttact 71461 atctcctgcg gatccttttt ttgttcaaac attatctcca atactttttt tgcaatggtt 71521 gtgcttattg ttccctggtc aaccaatttc accaactttg ccaggtattc cgccggaaaa 71581 ggtatgtctt cagcttccat tcccttgtcg ttaaggattc tcgaaacatc ccccagtata 71641 aaattactca cggcttttgc attattgcat tttcccgccg cctcctcaaa aaaatctgca 71701 agagcctttg agcttgtaag aatgaaagca tcatgtccgg gaagtccata ctcgtttaca 71761 tacctttttc ttcttgcatc aggaagctcg ggaagacttc tttttatttc ttccttccat 71821 tcttcatcca ccactatcgg cataagatcc ggttccggaa aatatcgata atcgtgggcc 71881 tcctctttag ttctcattga acagcttaca cctttgtgtt catcccatct cctggtttcc 71941 tgaacaataa ttccgccact ttcaataacc tcaatctgtc ttttggcttc actttcaatt 72001 gcccttacca ttgaccttat ggaatttaaa tttttcattt ccgtcctcgt cccaaattcc 72061 ttttggccct taggtcttac cgaaagatta acgtcaactc tcaatgaacc ttcctgcatt 72121 ttgcagtcgg aaacatcaat gtaccgtagt atgttcctaa ggctttccac aaaagccctc 72181 gcttcctgcg ccgaacgcat gtcaggctcg gtgacaatct caattaacgg cacaccgcac 72241 cggttataat caatcaacgt tcccgtttca ttctgatcat gtacaagctt tcccgcatct 72301 tcctcaatat gtatccttgt aatcccaatc ctttttgtcc ttccttccac ctcaatgtca 72361 atatatccgt cccggcatag gggaaggtcg tactgggaaa tttgataagc ttttggaagg 72421 tcgggataaa aatagttttt cctgtcctgc ttgctgtact ttgcaatgct gcagtttgtg 72481 gcaagcccgg tttttaccgc gtattccacc acttttttgt tcaaaaccgg aagcactccc 72541 ggcataccgg tgcagacagg acaaatgtgg gtatttggct ctcctccgaa atccgtggtg 72601 catgaacaat atatttttga tttggttgaa agctcaacat gaacctccaa ccctacaatt 72661 atttcatact ccatcccaac acacacctca aatccctgcc ctttttttat gaaactctgt 72721 gttttgttca aaagtataac ctacacgcag caacgtactt tcatcaaagg gttttccaat 72781 gagctgcagt cctatgggaa ggttattgcc gtcaaatccg cacggtatcg taagtgccgg 72841 aagtcccgca atattcaccg acaccgtata tatatctccg agatacattt caagaggttt 72901 ttcttttttc tccccaattt taaaggctgt ggtaggcgct gcagggccaa gcagaacatc 72961 gtatttctca aacacctcat taaaggcgtt tttaatcaac gtccttacct gaagcgcttt 73021 tttataatat tgatcataat aacccgagct tagcgcatat gtgcccagca atatccttct 73081 ctttacctcg acaccgaaac cttcgctcct tgttcttacg tacaagtcca tcaaatctgt 73141 atattctttt gctctgtatc catactttat tccgtcgtat cttgcaagat tggagctggc 73201 ctcggcagat gatataatat aataagcggg aatggcatat tcggtcaaag ggagtgaaca 73261 ctccgccacc tgcgccccaa gctcttttaa agtctttgcc gcatccaaaa ctgctttttt 73321 cacatcaaga tttgtgttgt caccgatata ttctttcggt atgccgattc tgattccttt 73381 cacgtcatta atcaaagctt ttgaataatc aggatacttt acgtcggcag aagtggaatc 73441 catcgggtcg taaccggtta tggcattcag taccatggcg caatccgtta catccttggt 73501 caacggacca atctggtcca tggaagatgc aaaagccacc aaaccaaaac gcgaaaccgc 73561 accataggtg ggtttcatac ctacgatgcc gcaaaaagaa gcaggctgcc ttattgagcc 73621 ccccgtatcg gaacccagtg caaatcccgc cataccggcg gcaacagcag cagccgaacc 73681 tccgctggaa cctcccggaa ccctttcaag gtcccatgga tttcgtgtaa ttttaaaata 73741 agaattttca gtggacgccc ccatggcaaa ctcatccata ttaagctttc ccaaaagcac 73801 cgcaccttca ttgtaaagtt ttttcgacac cgtcgcatca tagggaggta tgaaacttcc 73861 cagcattttt gacgcgcagg ttgtttttac atttttggtg caaatattgt cctttagtgc 73921 catgggtata cctgcaagag gtgattttgc ctctcccttg tctattcttt cctgcacctc 73981 tttggcctgc tctaaagcct cttcttcaag aaccgttata taacttccta ttttttcgtc 74041 tatcgcattt attctgtcaa gtaccgattg tacaagctcc acggcactga cctttctgtt 74101 ttttatgaag tcactcattt cgtgaaccgt aagttcgtaa agttccaccg tccgtcctcc 74161 tcatcttttg ccccttttct gaaacacatc tattcaacca ctttgggcac tttaaaacat 74221 ccgtcctctt tttccggagc attcatgagc attttgtctt ttggatatga atctcggacc 74281 tcatcgtctc ggaaaacatt ttttataggt atgacatgat ctgttggaat aatttttgac 74341 gtatcaagtt catttaattt atccacatag gatataatac tttccaggtc taaagcaagc 74401 ttttcctttt ctttttcgga aagccttaat cgtgcaagat ttgcaacata ttctattgtt 74461 tctttgtcaa ctttcataca aattcccttc ctacacaaca aacaatagca aaaatttcga 74521 aaacaaacaa caatatcccg ctaattaaat accattgata attatataaa atggtcatca 74581 atgcgtcaat tgtcaatact ccgcaagttc aaaatcacat ttttattatt tccgccgcca 74641 cggattttta aagcagaaaa acaacaaaaa agcggtctga aaagaccgct gtcccgtccg 74701 cacacacctt gtttatctac atctttcaag caaactcatt atcacaattc ccaattcctc 74761 atcactgacg tctttcttaa gaactttttc gtagcctctg aaattaaaac tgtatgtacc 74821 gtcaggcttt cttttggttg tgttaagtac aataccaagc gcttctttgt agtaaatgga 74881 aatgtttctt ttcccctttg caaattcatc ccatgatttg catttaagct tgctcataag 74941 ctggctgtcg gaatgaatta ttttgccgct gcacatcgcc atagaggacc ttaccaggct 75001 accaagttcc aaaggcttgt atggtgcctt cagaaacatt ggattttcca cggctctccc 75061 aataccatgt ttgtcttttt tgtaaggaat tacagttaca ttgttgtcct catcgaaaaa 75121 cacacaaaca ttgccataat taatactcgt cttgttgact gcttttttaa gtttgttttt 75181 ccttttaacg accaacagta taaacacaag tattagtatg agcactattg ccgaaccata 75241 gaacagatac attaaaaacc tgtcttccat atccaacacc ctgtttttca atcctcaaca 75301 gtccggcact tcactgcaat cgccgctaaa aggtttacca tcactttttt taatgtgttt 75361 ttcgattttt ttccctctaa gttgcaccta ataccagttc ttaacatatg taccccccta 75421 acaattaaaa tttatatatt aaaaatttat gccctcttta aaaatctcta tatatttctt 75481 tctatttcta ttatacaatt tttattatta atgaggcaaa aaatatattg caaaagtaga 75541 atttattcta tcatttttct aaatttatcc tcgtcaatta tttcaattcc cagctcttta 75601 gctttttgaa gcttgcttcc cgcatcttcc ccggcaagca cataatcagt ttttttagac 75661 acacttcctg aagtctttcc tccaaaactc tttataattt cttccgcttc ctttcgagta 75721 aagcttggaa gtgtaccggt taacacaaag gttttgcctt caaatctgtt gtctttgatt 75781 ttctttttac caaaacttac agtattcact ccggctgctt taagcttttc tacagtatcc 75841 ctgttctgct tttgcctgaa gaattgttca acactttttg ccattttttc gccaaattcc 75901 ggtattgcca taatatcttc cgcggaagca ttcataagag cgtcaagaga ctcaaaattt 75961 tcacttaaaa gctgtgccgc ccgaagtcct atgtgtctga ttccaaagcc aaagatcaat 76021 ctgtcaatat tattttgctt tgacttttct atcgaagcaa gaagattttc aacggacttc 76081 ttacccattc tttcgatgtt tacaagggtt tctttttcct tatgcaaata atacaggtca 76141 gctatctctt ttatgagccc tttttccagg aggacctcaa taatcgcagg tccaaggcct 76201 tctatattca ttgcatccct tgaagcaaaa tgaactattt ttctgtacag ctgggcggaa 76261 cattcaatgc cggtgcatct gtatgccgcc tccccctctt ccctcactac atcagcacca 76321 catacaggac attgttcggg catgttgaat tcagcctcat ttccactgcg tttttcaaaa 76381 accacatcca ctacttcggg aattatgtca ccggcctttc ttatacgcac cgtgtcacct 76441 attctaatat ccttttcttt tatataatcc atgttgtgaa gtgtggccct gctcacggtg 76501 gaacctgcaa gtctgaccgg gtcaaagatg gcaatcggcg tcaacacccc tgttcttccg 76561 acatttaccg ttattttctt aacaacagtt tctttaactt cagcgggata tttataagct 76621 acagcccacc tcggagcctt gattgtggaa cccaaaattt ccctttgttc cagggagttc 76681 acctttacta cggctccgtc gatttcaaaa tcaatctctc cccgttcttc tccgatgcgg 76741 tttatttcct cccaaacagc atttatatcc ttgcatacct tatatcccgg gcttgtctta 76801 aacccaagtt ccttgagaaa ctcaagagtc tcagaatggg ttttaaaact ttggccctct 76861 attctttgta tattaaaaac aaatatgtca agtttccttt gactggtcac tttcgggtcc 76921 agctgcctta aagagccggc ggcggcattt ctgggatttg caaaaagctg ctggcctgcc 76981 gcttcctgct cttcatttat tttgataaaa tcctttttgg atataaacac ttcgcctctt 77041 acctcaagca aaggcaaatc ccttttcagc ctcaaaggta ttgttcttat ggttttaaga 77101 ttttgtgtca catcttctcc aaccagaccg tcgccgcggg ttgcccccct tgtaaacaca 77161 ccgttttcat aaaccagcga aaccgacagg ccgtcaattt ttttctccac aacatactca 77221 acatcgtctc ccacggcttc cctcactctt ctgtcaaatg ccaaaagctc ttccctgctg 77281 aacacatcgg aaagactttg catctgtaca gcatgcacaa cctttttaaa tccttccagg 77341 ggttttcctc caattctttg ggtgggagaa tccggtgtaa tgaggtcagg tctttcctgc 77401 tcaagttttt caagctccct gtaaagctca tcatattcaa aatcgcttat ttccggtgca 77461 tcctccacat aatatttatg gctgtggtag tttaaaatct ctctaagctc aagtattctt 77521 ttctctatgt ccacctgttt ttccctccgt ttaacaatcg tagattttaa aaacttatct 77581 ttggaacaat catgccccat actttaaatc atatggaatc atacgcgtct taaatcaatc 77641 ctaccttttt cctgtgccac ccatctttaa aaccaccgcg tttatcacca ataccgcaat 77701 tacaatccac accacggccc acagcaattc cggcaatccg gtaatatttt ttaatcttgc 77761 catatccaaa ggtatacccg tgttccatcc ctttataatc gaaaactgct gattaatttt 77821 aaacaacacg gtatcaacca gcgtctcata aataatatat gcgacggaag acatcgctac 77881 cacatcaatt gcaatttcct ccacgccgcc tctttgaatc atataaagaa gaatcgcaat 77941 tgcagtaaat acagcagcat acaaaacagt accccttaat gcaggaacgc ttatggagat 78001 aaaaagatat attattgcca aacttccaag aagatatttt ttggcatttg tcttttttaa 78061 aaacataatc agtgcaaaaa acaatatact tcccaaatat ccgccgctgg atatcataaa 78121 agaaggaaac cacccttgtg cgccaaccat tgagtctccc attgacccaa atgcagcctc 78181 gaaagcattt gaaccataac cgaaaagaaa tgcaacaaca gcatgcccca tcttgtgaaa 78241 taacatggat aaaaccctaa acggcttaag tatcacctga ttccacaaca aaacaacagc 78301 aataagaata gcaaggtatt tccctatggt tttcatatcc acctcataat taatataatt 78361 attattttta tataatatta ttgcaaacaa attctatata aactgtattg ccgcattaat 78421 aatgcagcaa tttatttacc aagcttatac ataaaattat acatacacaa aataaaaagg 78481 aaagagattt cccttccttt tcgataaatt aaattcattt tgcaaattta cttcacaagc 78541 cacaagccgt ttcttcaaaa gctacaactg ctaattcgga attatcatat aattaccgtt 78601 ttcatctttt accatgccca tttcatcaag tgccttcatt accgcatttg caagagcctg 78661 cgcagctttt tgcctgaatg cgtcatcagc aagctttgcc ctgtccgacg gatttgaaat 78721 ataggcaatt tcagctatta ccgccggcat tacggttttt cgcaacacta ccagattggg 78781 ccgttcaatt ataccgttgt ccacggtacc aagagcgttt atcaattcct tctgaacaat 78841 tgtggcaagt tttttaccgt ccattttgct gtatctggga ttcgaactgg gacagtaaag 78901 agtctccgta cccttatatt cagaattatc aggcagggaa ttgctgtgca cactgataaa 78961 aagggttgcg tcaagcctgt ttgcaagttc aaccctcggg tcaaggtcaa caaacacatc 79021 cgtttctctg gtatatacta ctttgactcc caaatcctca agaagttttc ccagtttcaa 79081 cgatatatca agatttatat ccttttcata caaagtgcca ctgtaggctc cccagtcttc 79141 tcctccatgc cccgggtcaa tcaccacaat tacctcttta ggcttaatct cacccgcatg 79201 gcttgtccca tccgtatcac cagcgtttac aacttcattg ctattatcag tcaaataatc 79261 atttcctctg ccggatcctt tggacacaat tttgcttcca atacctattc caacgaccgt 79321 cagaatcaaa atccccatta caagaagaat gattctcttt gctggaggaa tatgcaaata 79381 acgtttttgc atctttttaa cgacactctt tttgttcata aacttccccg cttacaaccg 79441 tttatattga aaatcatact atcaaaccct tcgcaagtca aatcaaaaac tttgattatt 79501 ttcctgcaaa agcaaaataa aaaactgttt ttatactaag gacaacataa aacttgaata 79561 ttcaacatgc caattatgct gtccatatta tcgtataaaa acagttttat tataatataa 79621 attttaatcg taaagcagcc tgatttctac tggacatacc ggttgacatc gtttaatgta 79681 ataccttggt gaagcgcaat attaagaccg ttagcaatta cttttgcaat tctgtcaaca 79741 acatcgtcaa tttctttcgg agttaccaca aggttgccca catagggctg caacacctct 79801 tgtatcaatt gatatttttc atttctgtca atatttttaa gcatattgta aaaatgcgaa 79861 tcttcttttg cttctctaat aaggttgtct ataacgagat caattgtgtc atttgccatg 79921 gttgccgcat ccaccacggt cgggactccg attgcaataa ccggaactcc caaagtttct 79981 ctggaaagct ccattctttt gttgccgact cccgaacccg gggaaattcc ggtatccgca 80041 atctgaatag tggtattcac tctttccatt tttctggaag ctaaagcatc tatcgcaatt 80101 acaacatcgg gttttaccct gtcaacaatt cctcttacaa tctcacccgt ctctataccg 80161 gtaataccca acacgccggg agataccgca cacaccggtc ttaccccttc atcaacctga 80221 tcaggaacat actcaagcaa atgccttgtg accataagcc ttgaaacgac tttcggcccc 80281 aatgcgtccg gtgtgacatt ccagttaccc aatcctataa ccagaattgt tgagtcgtct 80341 ttaagattca atacacgtgt cagttctttg gcaagagctt tgcaagtctc ttcgtacaat 80401 tcctggtcgt tttccttgag cctgggcacc tcaagggtga tataattacc catcggcttt 80461 ccgatagccg cctcaccggt gggtgacgtt accctcaccc tggttattct tatatcttcc 80521 gtaccgtcgt tttcaacatc gactcccggc ggttcccttc tttcgttttt aaactcgttt 80581 tccttcaaaa gctcatgagc ttccagcaca agatccgttc ttatattcct ttccaccctg 80641 taatcctccc ttatcctttt tgccaaatgc aatattttcg aaagtcctat atatgctcta 80701 tttttcctca atagttaata ataaatacct gtattttaat tcacggtgaa ccaaagtact 80761 tttcgtccac tttgtctata tttatgtaaa aaatgcgaat ttgcccttgc attttcattt 80821 atatcgtgtt aaaatactgt ctgttaaata actcgcagga ggtgaaaagg ttgccaaata 80881 ttaagtctgc tattaaaaga gtgcgtattt caaagaaaaa gactcttcaa aacagcatga 80941 gaaaatcaat acttaaaact aatataaaga aatgcaaaca agctatcgca aataatgagc 81001 caaacgctgt ggaagctctc aagcttgcga taaagactat agataaagca gcagcaaaga 81061 acatcattca caaaaacacc gctgcgagaa aaaaatcaaa gcttgtaaag gcattgaaca 81121 ctgccctcaa acaacaataa aaacgtactg gaaagtacgt ttttatattt aaggcacgct 81181 tttaaagctc acgggttttt ccccggagct tttttatgcc gttttttatt cagccgccaa 81241 actgcagatt aatatttcca cggccgttct gtcgtttatc tgccccgtct ttatcgaaag 81301 atccagctca agagcttgtc gtattgcttc cttcagtttc tccaaagaaa aacagtcggt 81361 ctgccgtacc atttttttcg cggcataagg atttatcccc atctttgaac atgcttcttt 81421 tgcatccatg cccttgctgc acaaaagctt taattccaac aactgtttta attgttttgc 81481 tatcataaac aaaatctttg gcatgggttc ctttaaaata atcatgtcat ttaagagctt 81541 taaagccaaa tcaagttttc tttcggctat ggcgtcaatt aaatcaaata ttctgctttt 81601 tattgacttt gtgcaaacct tttttatact atctacggta actttctggc tttcgcccaa 81661 ataaagaaca actttgttta tttcatttaa tatttcagtc attccttcct cacatgtatc 81721 tataaggtat gatgccgtat tttcatcaat tgccttgccg taggatttga aaactttaat 81781 ggcccattta acaagttcgg ccggcttttg aaaaggaaat tccaccacca taccgtattt 81841 tttcacggca cttgttattt taagtctgtt atcaatattt tcctcataaa aaacaaggca 81901 ggtatgttca ggaatatttt gtaaatacgt gattaattca tcatttttat tatttgagga 81961 gcctgacttt tttgagttaa acaattccga ctttttaaca acaaccagtt ttttttccgc 82021 gaaaaacggc attgtctcac atgcttcaat aatctttgaa gcttccgcct ttccctctat 82081 cactatcttg ttcagcccgg tttgatccct gcttaaaata atttcttcta ttttgcccag 82141 gtaaaatttt ttcagatatt cttcttcgcc gtaaaaaaga tagagttttc ccagactttt 82201 gttttttact tccagtttca atttatctat actcatttta ctctcccgag gtttttgaaa 82261 ttcttcaaca atatagatta tatatcccct aaagtatttc ttcaagccgg gccaaattat 82321 aagtttgtca ttttctaaat ttttttctta aaaattctct tgacttatat tctgatttca 82381 attatactat tcattgccgt tacaaaaagc cgtaaaaaaa cggactttat tattacttgt 82441 ggcaatattt tttatatgtg caggggcctt tagctcagtt ggttagagca accggctcat 82501 aaccggttgg tccggggttc gagtccctga aggcccacca acaacgaaaa tcctgcccag 82561 atagctcagt tggtagagca gaggactgaa aatcctcgtg tcgctggttc gattccggct 82621 ctgggcacca tattttcagt tgaattttat aaatgttgta ataatgtttt aaagttaaca 82681 tacggaggga ttcccgagtg gccaaagggg gcagactgta aatctgttgt ctttcgactt 82741 cgatggttcg aatccatctc cctccaccaa aaaaacggtt ggagtatgaa ctccaaccgt 82801 ttattacatc tgtttttgct ttttatcctc atttatttgc atcaggcttc aattgagttg 82861 acaatttctt taaatctatt gcccctctct tcaaaattct taaacatatc aaagctggcg 82921 cttgcaggag acaaaattac tacgtccccg acggaagcaa aacggtaagc caccttaacg 82981 gcttcctcaa gagaggtaca tttttttatc ggaatatcgg agccttttcc cgacctttcc 83041 gtctcatccc ttaatgcctt ttcaattttc ggagccgtct gtccaattaa cacaaggcac 83101 tttacctttt ccgcaattac cggtcctaaa gcatcataag gtattttttt atcatagcct 83161 ccggcaatca gaattacttt atctttaaat gaattcaatc ctgcaatcgt tctggtgggg 83221 ctacttgcta tggaatcatt gtaaaatttt acaccgttga tctcccttac aagttcaatc 83281 ctgtgttcaa ccccggtaaa ggtggttgca acttttctta tgacatccct gtcgacacag 83341 tctattaccg cggcggtggc cgcaagaaag ttttcaacgt tatggactcc cggaattacg 83401 atgtcacttg ctttagcaat ttcagtttca gtttctccgt ctctgaaaac cagcatatcg 83461 tcttttagca tagcaccctt ttcaagtacg gtttttctgc tgaaataaac tacatctcct 83521 tttgcctcac cggcaaattc ccgggtaatg tcattgtcaa aattaagtac cagcctatcc 83581 tccgccgact ggtatctaaa aatattcttt ttggcagata catactcctc catggattta 83641 tgtacatcca ggtggttggg cgaaacattt gtcacaaccg caacattcgg gcttttagtc 83701 atggtgtgca gctgaaaact gctaagctcc aggacaactt tgtccgtatc ctttatctct 83761 tcaattttgc tgagcaaagg tatgcctata tttccaccaa gccagcactt atatccctgc 83821 tctttcagca tgttgtatat aagcgtggtg gttgtggtct taccgtcgct gcctgtcacg 83881 gcaaaaattt cggccgggca aagttcaaaa aatacttcca tttctgaagt tacctcagtt 83941 ccttcctcct ttgcggcaag aatctcaggt atatcatacc tcataccagg agtcctgaac 84001 aatatgtcaa agcctttcag attgtcaaga taaccttcgc ccaggctata tttaatatcc 84061 attcctttaa actgttccaa tgtggactta agcttaacct catccgcttt gtcgaaagcc 84121 gttatgtccg ccccaagccg gtacaaatat gaaattaacg gagtatggct gattccaata 84181 cccagtacgg caactttttt attttaattt tctttttaaa gtcatttaat ttggtattca 84241 aaatatttcc tccatttttc atttcaagta tattatatgt ccaaaagcca tgtaagatta 84301 taaataaagt acttcttagc aaattcttat ataaaaaatt tacattatta aaaaattata 84361 ttatttatta ttaacttata ataatcgtta taatctcttt cgattattgc ggtacatgta 84421 atgcatcaaa gttttgtcaa attttcttac ccacttttcc gatccgattt tcttggaaaa 84481 ctctatacac tgccttaaaa aaatttcttc actttttatc ttgctgttta acattctttc 84541 ctttattgac atgaaagtac cgtatcggtc gtaaagaata atgttctcac gacatatcat 84601 atataaaaat gttcccacca tttcatcttt gtataatatt tcctcaaata tttcgggagt 84661 gtaatttaaa atattgacat tcagatattt ctcacttaag agttccaact tgacagtttc 84721 attaaacaat ataaatttat cgagaggagt gtcattattt gataggacca gaaattcgta 84781 aacgctttgt gaggttttgt cgccctttgc cctggctccg tataaaacta tgctcattat 84841 ttttacatca actttttcag agcaccgttc cattatgtcc aaaatgcgtt ttagacccct 84901 gtcgtttgta agacttacgc ttctcatcca aatgcccctc ccatagtaat caatcatgca 84961 gacttttact atacataatc gtataaaaag cataaaagtc cggacaaaaa caaaacattt 85021 cgcaacaaag ctcacaaaaa ccgggtacct gtatctcttt atatattttc tttcgcattg 85081 acaaagtaca gtaatttttt attatctcat tggaacaatt tactctatcc gacagttaca 85141 atattatcat attttttacg ctatgcctag acttttttta attttataaa aaatataaaa 85201 atttcatctt gcattatttt attttttatt gtacaatatc tattgcattc agaaatgcga 85261 ggatggcgga actggcagac gcgctagatt caggttctag tggccgcaag gctgtatggg 85321 ttcaaatccc tttcctcgca ccaaataaac tgacaaccct gacatcaggg taattaaaat 85381 agcctgcaga aatgcaggct attttaattt tctgtttaaa agggtcgtaa taatgtccga 85441 ctctcttgtc cttttgaaaa aatcaaaaaa acttgatttt tgatgttgac atttaagttt 85501 gaatttgatg tactaaaatc aagggaagaa ttaaatataa aaacaataac agttacaaat 85561 cggaaagaaa ccatttttac aggggaaaat tcactgtata aactaacaca tgaagacctc 85621 agaagtctga ttttcaaggt tgcagaaaaa ataaatgaaa ggaaaacact gaagtccggg 85681 gatatagata aaattttcga ggttttaaat acagtttttg aataacaagt tgcggtttcc 85741 ctaaaaaacg tactgaagaa cccagaataa aataggggga tttgttatga cgttgcaaga 85801 aagaattgaa aagttcgaaa aagaaggctg gaaatacgaa cctgaattca gacttcatac 85861 cagaggaaat acaataatac agtttatggc actgacaaag gacggatact acagaaaaat 85921 ccagagcggc aagattggcc ctgctaaaaa gtatacgagt gatgaggata ttgaatttat 85981 gaaaaattcc tggggcggtg cccgtgaagg agccgggcgg aaaccaaccg gcagaaagaa 86041 aaaagtatat tatgttacag atgaagaaga tgtgcaaatc agagaatacc tgcaaaaact 86101 cagaaataaa caatagttca gaaataaaca atagtaaggt tattggaaga ctttaagcct 86161 aatccagagt gacggaacga ctcttcctcc ggtaatgcgg tggcccggtc acaagtccgg 86221 gcgggtaaga aggaggcaga aagaatatgc aatagtttaa aaatctggtt gtcggtcacc 86281 cataaaaccg ccataaagga ggcagaaatg gcaaagaggt atttaatata tcaagaattc 86341 tatttcgctg acatggtaag agacggctgg atggaataca tcagccctga agtagcagct 86401 ttatgtccaa ctggaattgg cggttggttc tcttttctca gagaggatga gaacggaaaa 86461 actattgacg aaattctgga cgattggaaa aacaactatg attttgtgaa gtacattctc 86521 aagataaaaa gattcccaat caatgacaga gaagaagtca ttagaatatc ttatgttgac 86581 gagcatgacg agctttgtga atgcatatat gttttagaaa aagaaacagt atagagaaga 86641 tgtctttctt cttatgatat agtcagggat aagcattgta gcataggaca ttgttttcat 86701 atacaagctc ttagtctgcg tcttattcat tcgtcaaggt ctttcataga ggtgtccaaa 86761 acaaaaagga gcctgttaca gctccggtat agaagattga atctatataa aaaggttttt 86821 cactggtcat ataaaatatt atcttagagt ttttaaaaac ttattaataa attattaata 86881 atttataaat tttatatgtt ttttatatgt tatatatcaa tcttaaaatg gaacttaaaa 86941 aagccatacc ctcttcataa accggaagtg ccgttcttaa ccggttccat accgggttat 87001 ctttcatatt cagaatcaat agccttttgg gcctcatctt tgaaattttt tgcaaaatct 87061 tccaccgaaa tgttgtctat tataatttct cttgctattt tattgaaaag aagattatca 87121 aaggtaggat acgcttgatg caacgatacc ttcccttttt caagcatcat tctcgccgta 87181 ttcttctctc catctgtgtc cagaaatgta ttaatccagc tttcgaatcc tacattgtca 87241 ttatagaagg gagatatttc ttcaaaaact ttagccactt ctcttgggtg ctttgcatat 87301 ttgggcatta cataaatttt gcactcctgc tgaacaggaa ctatgtaatc ggaagcttta 87361 ggtccttttg gaaaaaatac aaaaccaaaa tcatctttca tcgtattttt gagttcctgt 87421 ccgtcccagc catgtccaaa aaacatggca atattgcctt ctgaaaattt tcgaggagcc 87481 tcataccagt cagttggatc ttcaacaggc gccacaactt tatatttatt gtgcaaatcc 87541 tcaaaaaact gaagagcttc aatggcattt gggtcatcaa gagcatagat agctctgccg 87601 ttttcatcaa aatttatgat attggcattg tttgataaaa taagaggaga ataaagatta 87661 tgaccttgta ttaccaatcc ccacaggtca ttctctccgt cgccgtcttc atctctggtt 87721 gccatttgag ctatctcagc aaatttttcc caagtccaat ctccgttctc ctgaagcata 87781 tacgggtcag gcaatcccaa tctgtcaaac aacactttgt tgtaaaaaat ccccgttaca 87841 gtccagcaat agttcgtaaa tccgtattgt tttcctttat atcttcctat ttgcctaatt 87901 atagggggcc atttccgatc attaaagtca aagtagtcgt ccaccggaat tataaggtct 87961 gattcagcaa gcacgggaag cgccctggtc atttcaaaca aaacaatatc ggctataggt 88021 tctcctgata atactgatga ggtaaatttg cttacaattt gatcccatgt aatggttata 88081 tattcaattt tgcaattata tttttcttcc gctgccttgt gacgggctat tgagcttcta 88141 tcgtttggac tggcgtccca ccattgagca attctaacgg tgtaaccgcc caggtcaaaa 88201 tcttgctgag gtgtgctgct tatctgaatt tgtgtatttt cctctgcctt cgcaggcttt 88261 ttagaacatc cggtaaaaaa tatgtaagcg agcaaaaccg gaaaaaccag caacaacttc 88321 actgcggtgt ttttcatatg tattcctcct tcccggaaat agtaaaaaaa cattgaagca 88381 atatataaaa gccaagcatt tgtcagcagt ataagtcgca tattgaatag cacaagtcca 88441 taactatatt tatactatta ttatcggttt gactaaatat aatttttaac agcaaacact 88501 cttttgtccg gttcacatca ataccccaaa cagcattaat gaacgcaaaa aaaaagacac 88561 tcagaatttc caagtgtctg tttttgcgct taacacaata cttacttaca atcagcttcg 88621 gactaattct gtataaaatt ctttactctg ttgctgtcta aagccctgcc aagttcattg 88681 tctatctcca gagcagtatt aaatatgtac gtcaaactgg actgaaacct ggaatattcg 88741 cttttcatcg gaagtacagc cttgaaagag gtggcaaaaa tctggatagc cgtcatacat 88801 agtttaagct taagtattcc aatatatgta tttactggct gagccacagt ctctttcttt 88861 attcttacat cttcattttc gggaagaaaa tctgccaatc tctgtaccat cttgtacgtc 88921 ttgagcctaa tattttcatt caaaatccaa ggggttgtat ctcccggctt tccaaacaaa 88981 tgtctcgttt cactgttaac ctgttttatc tcttccatta tcaaatgaac gatattttcc 89041 aggtttttta agtaatcatc aacattagta atactgtcca attcatttat gcttttaagc 89101 agagcattgt tacagacagc ttctgtaaaa ccaccggtat aaagtccttc actaaacaat 89161 ccttccattt ttccctccct accggtgctt tcaaacggac atactttgaa gtttgcccgg 89221 ttaaaaacac caaataaaaa atcagtttaa tattttttat taataaatac tcttttacat 89281 aaataatcaa attaattata tcataataat cgtcacgcga tataaaatat attataatta 89341 tttattttat caattaaatt tttgctgaga agcaataagt aattgcaaca taataaacaa 89401 ctttgcaaat cctatttaat tgtattcaaa atactttcaa ccttattcct caaacgagga 89461 tcaattttta cggcttcctc caactctttt tttgacattt caacatttcc tgcatcatta 89521 tatataattc cgagaagaaa atgcccgttt gcagggtcga cctctgtcag catttgtgca 89581 tgttctaccg cttcgtcata ttttccctgc ttggcttcag acatagctaa attccacaaa 89641 gcattgaata atatggcttc attctttggg tgcattttaa ttatttcctc acccagcttt 89701 tcgctctcaa cccagtttcg ttcattgaga aaaccgctca ttaattccaa cttctttaag 89761 gattggttct gagtattggt aaatccgtaa taaagcgacg ttgacaaaat cacagccgct 89821 gcaaccataa ataccgtttt tttcttcaaa gacctgcgga aagaaggcag tccgacaacc 89881 cccgaagcca aaaagccacc caacaggcct ccaaaatgtc cgaaattatc aattctggga 89941 actgacaaac catatacgat attgatcaga agagtcgtta atatgcctct gccaaaacct 90001 ttcttaaaca gttcccggtg ctccgtccca taataaataa gagcacccag caagccaaat 90061 attgctcctg acgcccctac tgacggcgct attgaaaaaa tgaagcttac tatactgccc 90121 ataaggccgg ccatgagata tataaacaaa aacctgcctt ttcccattat catttcaaca 90181 gtagttccga ggacataaag ggaataggaa tttacaacaa gatgagtaat tccgttgtgc 90241 aaaaacatgg gagtcacaaa cctccaatat tctcccatca ttatatgagt attttccttt 90301 gctccaaaat ccaccaacag acttgacgaa tcaacaccct tggaccgcgc atagatttct 90361 atcaaaagcc agaccagaat gttgacagct atgagaacat aggttaccca gggttttttg 90421 tcttttatct caattttgta tcccttttca tttttcttcg ccaattcttt aaaatcaaca 90481 ttgccgtagt cactgtcaaa atcattgctg aaaaaatatt gaatttgatt atgaataccg 90541 taggatattc tgggatattc ataatacttg gcaaactctt ttttttcaac atttacactt 90601 atgcagcaca ggtaatttcc gttaattcct tcgttataat tttccgacgc taaaatctcc 90661 agtttatcct caggcaaatc cgatgaaaag acaaaaactt tgaagtagta ggtattgaat 90721 ctttctttta tctgctcctg ccttgacctt accatttcaa gtcctgtttt tatttgttcc 90781 ggtgtcaaca aatcaccgct tacaatttct gcaacaacgt aaccttcagg accgtacctg 90841 tgaagcattg cccggttgtc atctatcaca acgtttccgt tttcgtcgat gacaggaaaa 90901 taatttcccc tctcaatcag taatctgctc agtgccttta taatcaattt cttgttctcc 90961 tttcaaaggt ttaaaaagcc aatttaatcc aaatgcgtta tcgtacgcaa aactcttttt 91021 atattttcaa aatcaaaccc tctgtgcagt aaaaaagaat atattctttt ttgaatttta 91081 ggatctttca tgtcatattt gccaaatttt tttcttatca accgttctat cacaacgtcc 91141 tcgtcaaaat ccagttcact taaaacctgg tctgcaattt catcagacac gcctttttga 91201 ttaagttccc tctttaacat tttttttgct ttgggtttta attttattct gtcatagaca 91261 tacttctgag catatatcaa atcatttata tatcccatgg attttaattc agtcacaaca 91321 tttaaaatta catcctcatc atacccgtct tttcgaagct tctgcgaaag ctcggcttca 91381 gtcatgtacc tgtaagacag gtatttgacc gccttgtatt ttgcagtcct ttgacttact 91441 ccttttttta tttcttcaat ttcatcactt gacaactctt ttttgtcata aagacataat 91501 ctgaaataat cttcttccgg tattgaaaaa gcatattttt cgtctataaa aacagaaagc 91561 attccgcggt ttttcgtatc cttttccact gaagtaatca tcatatctac caccagcact 91621 caactttccg aaaatagcaa aaaaatccct gccatatttc aattatacta taaagcaatt 91681 tataaaatct acatatgctg caaaaatgaa tttccataaa acaaatcaca aaacaaataa 91741 aattcaacca tttgcatcac aaaaagaaaa aacaaatttt tcacaacata ttttttataa 91801 cacataaaac aacaaaaaat ccaaaaacgc tgtgaaattt ttgtgcgtaa aattcctatt 91861 acaaatataa aaacatgtca aaatattaaa taaaatataa ttaggtacat atcctgcgat 91921 atgcacctaa acaaaattca ctttaagtta tgccccgacg caatccgatc acatgaaata 91981 tcaattcctg taatattggc caatttcgtt tcccaaatta ttcttcatct tccaaatcca 92041 cttcatcatc agtatcaacc tgggcattaa tactcattag aaatgtctgg ttatagtttt 92101 ctctaatctt tgtctcaatt tccttcgcta tttcaggatt ttccttcagg aattgctttg 92161 cattctccct tccctggcca atcttctgac cgttgtagga gaaccacgcg ccgcttttgt 92221 ttacaatatc gagatttacc gcaacatcga gaatattgcc ttcctttgaa ataccctggc 92281 cgtaaataat atcaaactct gcttctttaa aaggaggagc aactttgttc ttaacaactt 92341 tgacctttgt cctgcttcct attacctcat ttccctgttt gatggactca agccttctta 92401 catcgagtct taccgaagca tagaatttca aagcccgtcc gcccggcgtg gtttcaggat 92461 tgccaaacat aactcctacc ttttctctga gttggttaat aaatattgcc gtcgtcctgg 92521 atttgttgat aacaccggca agtttcctta atgcctggga cataagcctt gcctgaagac 92581 ctacatggga atctcccatt tcaccgtcta tttccgcttt gggaaccaaa gccgcaaccg 92641 agtcaattac aataacgtca atcgctccgc ttcttacaag tgcctctgca atttccaaag 92701 cctgttctcc ggtatccggc tgggaaacaa taagattttc tatatcaact cccaggttct 92761 tggcatacac agggtccaaa gcatgctccg catctatgaa agccgcctcg ccgcctgctt 92821 tttgcgcctc ggcgataata tgcagagcaa ccgtcgtctt acccgatgat tcaggcccaa 92881 atatttcaac tattcttcct ctcggcactc ctccgactcc caaagctata tcaagcccta 92941 aagcaccggt gggaatggtc tctatattca tgtgggtgtt ttcacccagc ttcataaccg 93001 cccctttgcc aaactgcttc tcgatttgtc ccaaaaccat ctccagagct tttttcttct 93061 caatcattta atcatcctcc tatatatcga acatgtgttc ttaataatta tacattaccg 93121 caatcatgta gtcaataact tttgaataat tttacacata aagaatttca tttttttact 93181 atttttttaa gccttgataa agccatatct ttaaaataca atgcctcctc cactttaagc 93241 accaacacgg cagcaaaata caccaacaca cccagggcta tctgaaaaat gaggtttaaa 93301 agctgcacaa ccttggctga agtatccggt acaaaacaag cattcgttat aaaaagaacc 93361 attcccatta tcattgccga aggcacaacc ttaaaaagaa atctaagaag cctgtcaata 93421 taaatacctt tcatttttct gtttaaaata ctcaaaagca gaaaagcatt taccgcactg 93481 gcaagggaat aagcaagagc cattcctgca accccaagat ttgtcatttt ataaaacaca 93541 atacttaaaa gtatgttaat tattatagtg cttcctccaa ccaaaagagg agtgagtgtg 93601 tcattaatcg cataaaaagc cctgtttgtc acagtgacaa tggactggct caaaagcgca 93661 atggaaaaaa acatcagaac atttgccgca acacttacag ccccttcgtc aaaccggctt 93721 gtaaatttga aaatagtcct gattaccggc tcttttaata caataaagcc aacaccggac 93781 ggtatggtaa aaaacagcac ggtctttata cctttaataa gagtgttttt atactcatcc 93841 acctctccct ttgcaatgtt tgaagacagt gagggcagca tggcaatacc catgccctgg 93901 gcaaaaacac cgtatggaag ctgccatgtt ctgtccccga tattcagtgc cgttgccccg 93961 ccaacaccaa agagtgttgc aaaggtgctg ctgataactg catttatctg aacaatcgcc 94021 gaagatatca aagaaggtat ggcaagctta aagagctttt ttgacccctc atgcttcaaa 94081 tagaatttaa atctgtaaag cttaagattt ttaacggcaa aggacagctg gaacaaaaaa 94141 taaaccagcg agcttagcat tactccaaaa gcaacgcctc tgactcccca tctgctgacg 94201 ctgaatacaa ttatgctcag agcgcttcca atattgtaaa gagacggtcc gtatgccgct 94261 gccgcaaaac ggttgtagga gttcaaaacc ccattgcaaa gtcccgccat cataagaaaa 94321 gcaacagaag gaaaaagtat ccttataaga tcaacagtaa gctgtttttg ggcatctgtt 94381 tcaaatcctg cgccaatcag cgaaaccacc tggggtgcaa aaattattcc taaaaagcac 94441 actgcaacca tggcaacaat aacagtgttt ataaaagtac ctaccacttt ccatcccgtt 94501 tcttcatcat cccgggcaat ataacccgac agaacgggaa taagggccgc agacaccgca 94561 cctcctacca gcatgtcata catcagacct gtaattttga aagcaacggt ataagcatcc 94621 ccttcttcat taactcctat aaggttcggc acaagcattt ctcttacaaa tccggtgatt 94681 ctgctgacta tgatggatga catcacaata agagcagcgc cggtaagttt tttattcttc 94741 cccaaattgt atatcctccc ggttttttct ttgtttttta atcagcattt taccctttca 94801 gcttcattac atatcttctt accatgtcaa aagcattaag cactgtaagg tttcttattc 94861 tgtttctgtt cccggcaagc ctaagttccc ttacctccgt ccccaggcta tgggccaggg 94921 caacataaac caatcccacc ggtttttcat cagtgcctcc gtcaggacct gcaatacctg 94981 taaccgccag ccctatatca gttgaggcga ttttccttac accttcagcc atctccattg 95041 cagtccggct gcttacggca ccgtactttt ccaaagtctc aggcttaacc ccgaggtttt 95101 ccatcttggc ttcattgctg taagatacaa tacctctgtt aaaaaccttt gatattccgg 95161 gcacatcggt aagccttgct gaaatcagcc caccggtaca agattcggca gttgctattg 95221 taatgttgtt gtcaataagt atctttgccg ccacatattc cagctcttca tcttccgtac 95281 tgtataatgc ctctttgagt cttgaagcta tctcattttg caaaggaagt atttcacgaa 95341 agccttcttc ctctgtcctg gcttttgtgg taagtcttac ggtcacctgc ccgtcttttg 95401 cataagttgc tatggtgacc ctgtcctgtt tgtcaactaa atccataatc atctcttcaa 95461 gctgtgattc ccctattcca aaaaccctca gatattttga cactatcctg tatcctgatt 95521 tttccgcaag gtaaggaata acggtatcat caagcatcgg catcatctcc ggcggaggac 95581 cgggaagcat taccacaatc tttcccttat cttcaataat gcagcccggg gctgtgccgc 95641 tgttattctc aaccactgtg cacccttccg gaagatatgc ctgcttgaca ttattgtccg 95701 tcatttttcg gtttatcctg gtaaaaaaag ttttaatcct ctcaaggctt tcttcgtgta 95761 aaacaagctt tttccccaaa acttccgcaa cagtctcctt tgtaaggtca tcctgcgtgg 95821 ggccgagtcc tccggtcata ataacaaggt cgcacctttc caaagctgca agaagacatt 95881 ttttcagccg aacggaattg tcccccacca cactgtgata atacacattc acaccaatgt 95941 cattgagcct tttggatata tactgggcat tggtatttgc tatctgcccc attaaaagct 96001 cggttccaac cgctaatatc tccgcattca tattgaaaga ccccttaaat ttaaactttt 96061 tgtaacttat tatatcaatt agtgttataa aataaaaggg aaaaagaatt aaaatcaaag 96121 gtttcaagag cagccgtatc acccgtaaaa gtttcagccg attcaacctt tttacacata 96181 aaactttcaa aaattgatga cttacaatta tcaagtagga tataatatta ctaatgctaa 96241 acagttattg ataaaggagg aaggaatatg aacaataaca aagtaattaa aaaagtaacc 96301 gtagttggtg caggctttgt aggttccacc acagcttata cattgatgct cagcggactt 96361 atatctgaaa ttgtactgat agacataaat gcaaaaaaag ccgacggaga agtcatggac 96421 ttaaatcacg gcatgccttt tgtaaggccc gttgaaattt atcgtggtga ctacaaagac 96481 tgtgccggat ccgacatagt aatcattacc gccggtgcca accaaaaaga aggcgaaacg 96541 agaatagatc ttgttaaaag aaacacggaa gtattcaaaa atatcataaa tgaaattgta 96601 aagtacaaca acgattgtat tcttctggta gtcacaaatc cggtggatat tttaacctat 96661 gtaacttaca aactatccgg attcccgaaa aacaaagtaa taggttccgg aacggttttg 96721 gacacagcca ggttccgtta tcttttaagc gaacatgtaa aagtggatgc acgaaatgta 96781 catgcttata ttattggcga acacggtgac accgaagttg cggcctggag tcttgcaaat 96841 attgcgggaa ttcccatgga tcgctactgt gacgaatgcc atcagtgcga ggagcagatt 96901 tcccggaata aaatatatga aagtgttaaa aatgcagctt atgaaatcat caggaacaaa 96961 ggtgcaacct attatgccgt agcccttgcc gtaagaagaa tcgttgaagc cattgtaaga 97021 aatgaaaact ccatccttac cgtttcaagc cttttggaag gacagtacgg acttagcgat 97081 gtatgcttaa gtgttccgac aatcgtgggt gtaaacggta ttgaggaaat attgaacgtg 97141 cctttcaacg atgaagaaat tcagcttctc agaaagtccg gaaacactct aaaagaaata 97201 ataaaaacac tagatatatg aaagttctcc ttttctttta tgaaaaggag aactttcatt 97261 attgataaat atataaacta gtatataatt ttaatataaa acctatttta cataatggaa 97321 attatctatc gggggaggaa atatgaacaa ttcagtggaa attttaaata aaatcgtgtc 97381 aaatattgaa aaagtcattg ttggaaaaaa gaaagctatc gagttgatat taatatcact 97441 tatttgcgat ggacatgttt tgattgaaga tgtccccggt gtcggaaaaa ccagtattgt 97501 atcatctctt gcaaagtcgg taaatgcttc ttttaaaaga atacagttta caccggatat 97561 tcttccttca gacattacag gatttacgat gtacaatcag aaagaaggta aattcgaata 97621 tcatcccgga agcattatga gccagataat acttgcggat gaaataaacc gaacatctcc 97681 aaaaacccag gcaagccttc ttgaagcaat ggaagaaaaa caggtgaccg ttgacggtgt 97741 gacatacaat cttccaaggc cttttatggt actggcaact caaaatcccg tggagtatct 97801 cggcacctat cctcttcccg aagctcagct ggacaggttt tttatgaaag tttccatagg 97861 ttatcctgaa aagtttgaag aatccgaaat actgtcaaga tttcacgacg aaaacccctt 97921 ggaaacctta aaacctgtgg cggacagcag cgatatactg aatattcaaa gcgaggttaa 97981 aaaagtttat gttgacaggt ccatcaacaa ctacatagtg gatatagtaa gccggacaag 98041 attccattcg gaaataagtc tgggttcaag tccaagaggt tctctttctc tatacagagc 98101 ctcccaggca tgggctttat acaatgaaag aaactttgta attcccgaag atgtaaagct 98161 tatgtcaata cccgtgcttt cccacaggat tatactaaag caggaagcaa ggcttaagaa 98221 aatatcgcct gaagaaataa ttgataccat aataaaatct gttaatgttc cagcggtgga 98281 taaatatgca aagaaataga atcttatatt catttttata tgttctgtct ttaatattta 98341 tatattttta cggcggcaaa atcccttaca tgctgtttta taccgtcttg ttgctgcctt 98401 ttgtttccat agccataacc tccattgcat ttgtcagatt caaatatgtt caggatattg 98461 ataagcgaag tgtggtaaag ggcgaggaaa taaactacac cttaagcata cataatgagg 98521 attttttcct ttatccttac attaaaatta acttttttaa taatgacaca attttttcaa 98581 accaatttga accacaatgc ttttctctcc ttccttttaa gaagaaaacc tttagctaca 98641 agctttgctg caaatacagg ggagactttt tcgtgggggt aaagagcata gaatttgaag 98701 attatctggg tattgtaaaa tttgttcacg agcccatttc aataaaagaa attacagtgt 98761 atccccgttt gatcaagctg gacagcctga agcttaaaac agactatttg tcggaatccc 98821 atgctctgtc aaacagcagg tttgaaaaca ctctgacctt ttccgacgta aggaaataca 98881 cctatggtga cagcatgaag aagatacact ggaaactttc ttcaaagatg aatgagcttc 98941 ttgtaaaaaa ctttgaaggt tcgtcccatg caagctccgc aattttgctg gatcttaaga 99001 aaagcaaccg ttccttcgaa gaaaactcga taattgaaga tatgcttatt gaagcctcca 99061 ttgccgtaat ttattattgc cttgtcaact ggataccaat aaattttata tattacaaca 99121 gtaaaggttt taataccatc gaggcgaaaa acgctttgga atttaaagaa atctatgaaa 99181 ttttatccgg catcaaattt gaaaatacca tggatataaa agacgtcctt aatatttatg 99241 tgaaaaacag tgtcttgaaa aaaacttcga tactcctttt tacgtctaat ttggattatg 99301 gactctatga tgagatttac aaaacaaaac taatggggta cgacataaat ttagtgtacg 99361 tttgcccgaa acatgttgta aataccgctt cttttgaagt aaacaatatt ttaaacgagc 99421 ttttggaaat tggagtcatg gtttataaaa tacaaaccga agatgacatc aaaaatgtgc 99481 tggagtatag ataaaacatt ttcgcaaaaa atgaggtgat acaaaagatg gacggcaaaa 99541 aaattctcga ttatctggcc ggttttgttc ttgcggcttt aatgagtttc agcctggttt 99601 atcctcttac caccacgctg ggtttccctt attcgtcttt ccgtatttta gggcttgtaa 99661 tctttattct gtttatatat tcggtgctgt ttgcaaacag aaacgtctca agaatttctg 99721 tgcctcttgc aataatttcc atggcagccg gcattgtctt tttagcggtt aaaaaagatt 99781 tggcatatat catccaacct tttcagtggt ttactaaata tatttatgac gaagccatac 99841 ttccggacaa ttactatcct ctttttatta ccgtgatttt agcgctgtcg cttacactgc 99901 ttgtatttat atttaccatg aaaaaattca attttataat cattctctca agcggaacag 99961 ccatctttgt atcccaatgg atattgaatt ttttcgtgcc gtccgcctat atatcttttt 100021 acacctttgt catttcaata ctggcatact atcttgtgca tatatacaga aaaaaaagcc 100081 tggaaaattc aaataatgat tttgcctccc cttcgaagtt catactggga atcgctccca 100141 tatgcgtcgt aattgtcttt ctggcaaatt caatacctgt aaggtcaaaa cctattgagt 100201 ggaaatggct ggataacaaa atcaacagct tttacaatca gctcggattt ggcactctcg 100261 gcaaaggttc cgcaggtttt gattccgatt acttttcttt ttattccact gccggatttg 100321 gaaatgacag caatttaggc ggaaacataa cacccaacga tataaagata atggaagtta 100381 ccaccgatcg cagcatctac ctgaggggac gggcatgtaa tttatatacg ggaaatagtt 100441 ggttgaattc acaaccggac aacatccctt tggacggcac aaataaaatg agctttgata 100501 ttttagaaat gaaaacaggc ttacccctcc ttgtcaacaa actgaatccg gaaaacaaca 100561 catacaagct ttcagacacc gatggaatca tccccaacat tatttcaaaa cataatgtca 100621 aggtaaaata tgaaaatgtg agaaccaaat ccctttttgt accgcttaaa tcagaaaact 100681 tcatttttcc gtccaaagta gctgatgcag tattaataaa ccaggatgga atacttacct 100741 ctaataaatt cctaaagaaa gatttcacct attcctttga aagttatagc ctaaatactg 100801 tcagcgaaga tttcaaaaac cttctgagac aaagtatgcg cggcctgtac agcgttgaac 100861 tgaacagact tacagatgaa atctatgaac atttgtacag cgaatattta aaggatctgt 100921 tggatgaagc agaaaggata tacaattccg atctttttat attaaataga tattcagttc 100981 aatttccaat aaaaaatata ataagaaata ctccggataa tataacttta agcgacctgc 101041 tatatgaata cctcgttaat gttttcatag atgaatttaa tctcgacaga gttttcgagc 101101 gcgaagattt ggaaggatat ttccaaatga tcattaacga gcttaacaat tcggaggaca 101161 taaagaagct tgcgcaactt aggtctttaa gctccaattc agtctatatt tacaacactt 101221 atctaaacat accctccgag cttcctcaga gggtaaaaga ccttgccgtt tcaataacag 101281 ccaatgaaac caataatttc gaccgggcaa aagcaattga aaaatatctt tctgcaaatt 101341 acggctacac actgactccg ggagataccc cgcctgacag ggattttgtg gactacttcc 101401 tttttgaaca aaaggaaggc tattgtgtgt attttgcctc tgccatggta atccttgcac 101461 gcagtatagg gcttccggcc cgttatgttg aagggtttgt tcttcccgtg agatcaaaag 101521 acggtgtcta tgaggttaca aacaaacagg cccacgcctg gccggagatc tactttgagg 101581 gattcggctg ggtctctttc gaaccgactc ccgtctatca gcaaaactcg ttttacagtt 101641 ccggcagctt taggcccaac atgagcggaa tgcttcccca aaccaacggc acagggcttc 101701 aaaaccaaaa caatgatgaa ggcaacaagc ccgacatggc tccccaacct gtccaaaacc 101761 aaaatccgtt tatcaatatc cttttgatta cggccgggat acttgcaggt ttggtttctt 101821 ttgtgttgat tatcgtgggt atcaataaaa tcagaaaaaa acattggctt aaatccattt 101881 taaacatgtc gcccaaagaa gcggtaataa agttatacga aacatacctt aatcaccttt 101941 tatatcaata tatgcctgtg cgtcccgcgg aaacccctct tgaatatgca aagaggctcg 102001 acgattatgg atattttgct cccaggaagt ttactgatgt tgcatccata ttcgtaaaag 102061 cgagatacag tcaaaacgag gtgaccgagg cagacagggc aagtgctttg gaattttaca 102121 aacccatagt tttaaaaaca cgaagctcca tgggacgcct aaagtatttc ttcctggcgc 102181 atatacttgg aaagatataa gataatttca aagctttacg atttgtcaag agactgtgga 102241 gactctttta agcctctaca gtctcttaac ttaagattct gcaataattg cgatttagaa 102301 ggcagtcata aatttttata aaaaaacagt ctttattaaa agaaaggtct tttgggtatt 102361 ataatcattg caacaatata aatgataata ccgccgacaa atccggtcaa aacagtggct 102421 attacagcaa taagccttat gagagtcgga tcaatctcaa aatattcagc aactcctccg 102481 cagactcctc caattatttt atctgaattc gaaagataca attttttcat aaatatcctc 102541 cttcttaatt ataaaaaatc aaaatcttcc acaacacata atatactacg ttaaaccttt 102601 tgtttttgtc tgaaaaaaaa caccggttat ttcccggtgt cttgtctttt cgctcaagtc 102661 ggctgttact gatacaaagg atatttttcg cacagcattc ttactctttc ctttactttc 102721 tctttcgaat tctcataatc cgtaatggtg agattgataa gatccgctat ctcaaccata 102781 tcctcttctt tcataccccg tgccgtcacc gcaggtgttc ctattctgat accgctggta 102841 acaaacggac tttcagggtc aaaaggaatt ccgtttttat ttacggtaat gcaaacctca 102901 tcaagaatat gctgaacgta tttacccgta agacctttat ttcttaaatc aaccagcatg 102961 agatggttgt ccgttccacc ggaaacaagg tcaatgcctt tctccatcaa agcgttggca 103021 agagttttcg cattttttac tatctgctgc tgatactgct tgaattcatc ggtcaatact 103081 tcggcaaagc ttaccgcttt tgccgcaata acatgcatca gaggaccgcc ctgtattccc 103141 gggaaaacag ccttgtcaat catttttgca tgctcattgc cgcacaatat cagtccgcct 103201 ctcggacctc tcaaagtctt gtgagtggtg gtggtaacaa aatgtgcata aggaacagga 103261 ttcgggtgca gtcctgctgc aacaagacct gctatatgtg caatatccac catcaaatat 103321 gctccgactt catccgcaat atctctgaaa gccttaaaat ctattattct tggatatgca 103381 ctggctcccg ccactataag tttcggcctg tgttcctttg caagctttct cacttcgtca 103441 tagtctattc tgcagtcttc cttccttact ccgtaggata tgacattata atattttccg 103501 gacatgttga cagggcttcc atggctcaaa tgccctccat gggaaagatt cattccaaga 103561 atcgtatctc cgggatttaa cactgcaaaa aacacagcca tatttgcctg agcccctgaa 103621 tgcggctgca cattcgcatg ctcagctccg aatattttct ttgcccgttc aatcgcaaga 103681 ttttcaatta tgtcaacaaa ctcacagcct ccgtaatacc tttttcccgg atatccttca 103741 gcatacttgt tggtcagagg tgtacccatt gcttctatta cggctttact gacaaaattt 103801 tcagatgcaa taagctctat cttgtttctc tgacgattaa cctccaattc aattgccttc 103861 gcaacttcgg gatcgatttt tgatatttca ttcaaattaa acataaaaaa acctcctata 103921 ttaataaagg gaacaataat ttacggccaa ttgcaccaaa ggaatagaaa aaaagccaaa 103981 tccaaaggat ttgacctccg aaaagacaga caaaaaggaa gtatcgaact gtatacgtcc 104041 ataaaaaata aaattccttc tctgtccttt tgcctgagag atttctgaac agttccccaa 104101 aaactgttca tttgcccctt cggcgccttt acggtctctc cagaggtgcg tccggccatg 104161 gtcacaaaac ctgaaagtat cactccttcg gtgcattgga acatctccaa tgactctccc 104221 atgacaatca tccgctcata ttcaattaac aaataaaatt ataataaatt attacctact 104281 atgtcaacaa ttattttcga cagatatttc aatatcaatt ttattgattt tgcggtttat 104341 acaaccttgt acaattcatc cgaacccggc tcggaaatgt caataacttg attgtcttca 104401 caaacaagtt ttctacccaa atcagccgtt atttttccga taacagcggc ctctataccg 104461 ttgttttcaa gctctttcac aagttcccgg ccgtttttgc aggttattat catacatccg 104521 cttgatataa gccttaaagg atcaattcca taaactttgc aaatcttttg tgtctcatct 104581 tttacgggaa ctttgctttt atatatcacc gctccggttt ccgaggcctc agtcacttcc 104641 catacagctc caagtattcc gccctcggtc acatcatgca tggaatttac accaaacgtt 104701 cctgctataa ttccttcttt tagcacactt acgtaattta tgaaagtttt agccctttcc 104761 accgcttctt ttccaattat atctacaagt tccttttctt tgtcgtgggc tataatggcc 104821 gttccttcaa tacccgcggc cttagtcaca ataatgtcat ctcccggctt tgcccctgat 104881 gtagtaacca gcttgtcctt taataccttt cccaccgcag tgctgattat cactatcctg 104941 tttacggcag tggtaatctc ggtatgtcct cctatgatat caacattcag agaatttgcc 105001 gtatcgacaa tttgggtcat gacattttca atatcctttt ctttcgtacc ctccggcgca 105061 agaattgtca taagaagccc caaaggctca gctccacacg aagcaacgtc attgcaggat 105121 acatgcactg caagacgccc cacctcgtta accgcacctg taatagggtc cgacgacaaa 105181 acacaaacat cttttccaaa atctacggcg cagcaatcct cccccacctt cggccttata 105241 agtatctctt ttctgtttgc ttttatcttg tttattatca attccgtcag cacactgttc 105301 ggaactttgc ctatatccat atttgcctcc gtaaaaagct cacgcgtcaa atttgccagc 105361 atgtaaacac ataagtatgt aaaacttcca aaaatatatt gatataaata tatcataatt 105421 tcaaataaat ataaagaatt aatcgggcaa aaataaaatt tttatgcttt ctcctttgct 105481 tcttttgctt ccttagccaa atgatattgc tctctggtac tgtcaatcaa agctttattt 105541 tctctggccc caggagagct tattatcttg ttgaaccaaa atatcgcatc atcataattt 105601 cccacacgcc ggctaagttc tccaatcata tacacacatg tgtgttcatc aagttttccc 105661 accgggaaag gttcattttc gtaagtttca cgataatacc ttaaagcatg gtttaagaat 105721 tttatctcct gctgctcatc ttttttcatt ctgtaaagcc acgcaattct caaacacact 105781 tttgcatatt caatcggttt cggactgatt ttgcaaaggt tgtaaagtgc aagtttaaaa 105841 gcttctatgg ctttgtcaac atctctttct ccacagaagc ttctaggttt ccaatacttt 105901 gaaatatttt cttttactat ttttgcctct atcggcgaaa tgttctcgaa cctttcctgg 105961 agcgcagcat aaccacagtg ctcacaaacc catacctcat aaaaaagagg atttacactt 106021 tcataataga cgcaaaaatc cgagtcccgt gatgcaacca cacagtcttt cgatttaacc 106081 tttgtaactt caattttgtt ttgacacacc ggacatacca cactcttgtt atacaatgaa 106141 tcaagcatta atccatccct cttttttata tagtttgttc ttccatagct tcttccttta 106201 cagtttcttc tccgccttcc gtatcattgc tgtcataagg ccccactctt tttaaacctt 106261 gtacaggttt ataaatatct tcggatattt tttccctttc aataagtcta ttattttcat 106321 aagtttccct gtatactatc accttcaaac cttgcaccgg ctccctttca attttcactg 106381 ctcctttggg cagcgacttg tcgacaatta tctcatcttc cggaggagaa atacgttcca 106441 caacaacaga tttcagcctt acatcataat ttgaatttct ttttgctccc agcagcttta 106501 tatctatcct gtttccgaca accgatgcac ttataaggca ggcacgatcc gtattgtttc 106561 tgaatttgaa gtcgatgtag ccttccgata ttgttgcgtc ctgacctggc tccacatatc 106621 ccaaaggcat tgaatgtttt accctttcaa ccacctcaag ctttgccttg agtactgcaa 106681 catacaatgt tgacgtaacc tggcaaacac cacctccaac tccttcaatc aagcggcctt 106741 taactatgac aggtgcgtct ttgtaaccat tttcttttgt tcttgacccc aaagaagcat 106801 ccatggaaaa tgtctcaccg ggaagcaaca ctgtgttatt gattctttca cacgcaagtt 106861 tgatattatg gcttctgttg acattggctg aattaaaaac agtggaaaaa gaggaaatta 106921 cctcttcaat atgagaaata tccttgtaca taattttcgg ataaacattt gtgacttcaa 106981 gttcgaaagg cgagaaatcc ctctttatta atttattttc taacaaacca agatttttgt 107041 caacatccac aaatcgcccg ataatctctt tttcaaacat aatattgcca ttttggtaag 107101 ttaccgttgc atctttcgga ttttcgtcaa cttgcttttt gatgctggta atatattcct 107161 caagaagagg ccttgaaaag acaactttcg ctaaaacgtt ctttttatca gactttaaat 107221 tccttatggt tttaagcctt tttaaaacac tgccttctct tcctattgaa taggctcttt 107281 ttattgcatc atccacaagg aaatcgtaag atatatctga aagcccgatc ctccatgtca 107341 tgccttcata gtttagcaaa agactatttt catatacaat cctgtcaagc tttttttcca 107401 ctttttctct tgcctcatca acagtcaatc cggatacatc aatcccttca acagcaatac 107461 cgtcgtaaaa agtttttctg ttcagaacaa ctaccacata agtcgaaact gaagctatta 107521 caagcaacaa aaggcttgcc gcaaatatta aaattttagt tttgtttttc gaaaaaaaat 107581 caagcaacat atccatacct tctatgtcca atgattttac ccttcaactg aacatctctt 107641 tatatagata ttgttgcttg ttaatataat attacataca tatttattta attttatttt 107701 ttatttacct ttaatccctc gttatcgtca aaacctcggt attttcaact gccttgttta 107761 tcaattcttc catgttcagc ctgctttccg aaagctgtat tctttccagt ttcggcttgg 107821 tggtgggatg ttttgcgaca aaaaccgtgc agcaatcctc ataaggaaga atcgatgttt 107881 caaaagtacc gatttttttg gcaatatcca caacctcgtt tttatccata cctatcaaag 107941 gacggaaaac cggaaggctt accacggcat ttgtaaccac aaggctttgt attgtctggc 108001 ttgcaacctg tccgacactc tctcccgtca ccaatgccag agctccggtt ttattagcaa 108061 ttatttctgc tattctcatc attgctcttc gcatgattat tgtcaattct tcatgaggac 108121 atttttcgtt tatctccagc tgaatctcgg taaagggaac aatatgaagg ttaatttttt 108181 ggcagtatgt ggcaagaatt tttgtaagtt caataacctt ctcctttgcc ctctcactgg 108241 tgtaaggata actgtaaaaa tgaaccgcct ctatttccac acctcttttt gctatcatcc 108301 aaccggctac cgggctgtca atacctcccg acagcaaaag cacagccttt ccgttgctgc 108361 caaggggcat tccgcaaact gcctgtatta tctccgagta aatgtatgta aactctctta 108421 cttccacata taaaatgaaa tcagggtttt ttacatcaac gctaagctca ggcacatttc 108481 ttaaaatata tcctcccagc tgcctgctta tctccggtga atccatggga aaacgcttgt 108541 ttcccctctt ggtctcaacc ttgaaagtct tgtacccttc ccgatttatg aggtccttta 108601 ccatttttac cgagttttct tttatgcact caaaatccga atctatcttc cacaccgtac 108661 ttactgaaac aattccgaaa acctttgaca aaagttttaa agcctcatca aaatcatagt 108721 tttcttccaa gggctcaatg tatattctcg cctgggactt tgtaatgcgc accttaccca 108781 gcttgtgaat ggcccttttt atgttgctca taagcttgtc ctcaaaaata ggtctgttca 108841 atccctttaa aagtatttca ccatatctta ccaaaattac cttcttcatc ttcttcctcc 108901 acgttttatt cttatttttg gcaaaatatc ttttatggct tccacggttt ttattatatc 108961 ctcttcgttg ttaaacgacg aaaaactgaa tctaatcgcc ccttcaatta tttcaggctt 109021 gattcccatt gccctcagca catggcttaa aacctgcttt ctggaagagc aggctgctcc 109081 tgtcgataca aatatgttct tcgtctccaa atggtgcaaa agcacctcag cacggacatt 109141 ggggaaagca gcattcaaaa tataaggtga tgatccttcg ggagatacta tcaccacatc 109201 ctcaacctct tttttcagca tatccaaaag catgcttttt aacttctcac aatattttga 109261 actttcttcc attttcctga aggtaatgtc caccgccgct ccaaaaccac agattccggg 109321 aacattttca gtaccggacc tgagttggct ctcctgcccc ccgccgaaaa taatcggttt 109381 tagtttaatg tcccggcggg tatataaagc cccaactccc ttgggtccgt gaatcttgtg 109441 agagctcatg gtcaaaaggt caattccttg tttttcagga gcaattctta tctttccgta 109501 cgcctgaacc gcatcaacgt gaagaactat atctttgttt atactgtttt ttacctccac 109561 gattttatca atgggttgaa ccgctcccgt ctcattgtta atgtaaatca cgcttataag 109621 agaagtttct tcatttattt tttttcgcag gtcatcaaca atcactatgc cgtttttgtc 109681 cacatctata aaatcaactt tgtaaccatg ttgggacaag ttgttaaaga cctccaggac 109741 agaaggatgc tcaatctttg tcgtgataat gtgctttccc ttccttggat ttgcaaaaag 109801 gtatcctgca atggcaaggt tgtttgcctc ggttccgccg gaagtaaaat aaatctcatc 109861 ccttgacact cccaaagatt ttgcaacaat ttcccttgca tttctcacca ttcgttcggc 109921 ttcaatacct ttggtgtgca gagaagatgg attgccgtaa acttccctgc ttatatgatt 109981 tacaaagtct ataacctcat catacggcct cgtagtggca ctgttgtcaa gataaatttc 110041 cctgctcatt ttaatccttt ccaagtctcc tttaattcat attttattct acctaagtca 110101 aattaagact tatcacttct aaatattcta acacactata tatagtttaa ccaataaaat 110161 cttcattttc aaagaaaata ttaaaaaagt ccttcctcaa cagcggaaag actaatatct 110221 cctaaatctg acaaaatatc cactataaac ttgattaaaa tcaatagtct tgattaaaat 110281 caataattaa gaagaatttc ttttaattaa tctgtaatct aagattatct gtaatccgaa 110341 tcaagccatt tcaaatagtg ataaagacac tttaaattgt tttccgatat gccccggatt 110401 tcaatgccat attcgtaata gtcgtttact ttgtttttcc tcacaacagc tccgctaaag 110461 acaagtttgt tcgttctgtc cagcaaaatc tccacttcaa gaacatcttc cgttgtaagc 110521 tgttcattgc aattaatttt tataccgccg gaactcatgt ttttcacaac tgcaaaaaca 110581 agcttggaag tcccgcacac tctgatattg gccataagac ttacataaaa tctctcatgc 110641 ttgcgcaaat ctttcaattt ttcaactttg tttatcttca catcaatgat caggggatta 110701 atatcataaa cgtggttgat atttccgtcc attacaaaaa gatcttgagt attggaatag 110761 tttacgacaa cgtggtcacc cggaaagaaa agtgtctctt ttaaaacgtc ttttgcctca 110821 acttttatac tgtcgtcagt tttcccgaga acttcggcat ttatgtactc gaacatttta 110881 aaatgcttta tatcaactcc agagccaagt ttaacgactt tcgcaggatt cctgttaccc 110941 aaggcattaa acagcccggt gcccccgtcc agattatacc ttgccatatc tccactcctt 111001 ccgagttgaa ttccaagcat caatgtgact acttggaaaa tttctatttc agattatgat 111061 aaataagctt tgcatccacg cttgccccaa gcattgattc aaagaaaaca aaactgtctg 111121 gaatgtttgt taataggata aacaattaga gaaaaacctt tatataatta attatagcat 111181 taattatttt caaattacag tccattattt aattttttaa gaatagtaat attttataaa 111241 aaaatcgtaa aatagtactt gaaacccttt attttttaaa aatgctgtgc tataataaaa 111301 gtaagttcaa tatttcctcc cgaaaaaggt ataaggagat ataaactgtg acttatgaaa 111361 cagggcaaaa tcaccgaaag gtgatgacgc aaagccatgg gtctactgtt ttaaaacaat 111421 gttttaaagc tatgatcgcc aggctgccat taaaagtcct gtttatactc ttcaaaataa 111481 atgtaaagga aataagtcag gtatatttcc ttatacctac ttttttttag cattttatcc 111541 tgtcaagagt cttgataaaa tccagcttgg tgtagttttt ttcaagtctt tctttcatat 111601 accgttgtga aactttgcca agttcgtcca acacactctc cgatacctca aaactgaaca 111661 aattgctcat tttactgtgc actatgtaat ttagtgcctt tgcggcacct tcggaaattt 111721 ttaatgctcc tttatcattt tcaaggcatt tgctgcacaa aaatccgcat tttaagaaac 111781 tgaaatacat actgtcaaaa acggtgctgc cacattttat acagctgctc acccacggcg 111841 catatcccat tgttgaaaga agtcttattt caaacactct tactatttgc agcggcgacc 111901 tgtctgtttt cgaaagcatg tacaatgagt ttaaaaaaag ctgcaacaac ctggatgcag 111961 gctgattttc caaaattaca tcatttacta tatccatcat atgggcagca tatgttaatc 112021 tttcaagatc atttcggata tcataaaaag actcaataac atcacagcta ttgacggtat 112081 acatgtcttt gcctttaaag agaacaaatt cgctgtagca taataattgt gtccctgcaa 112141 ccaggtgact tttcggtctt cttgcacctt ttgccaaagc ggatatcttg cctttattct 112201 tggaaaatat tgttattatt ctgtcagctt cccccgtatt aacttctttt ataactatcc 112261 ctgaagtttt taaataattc attttctttc tatcctttta atgatgagta gttgcaacct 112321 catcccttgt tatctcattt tctcttgcgg ccttggtttt ttcctctatt tctttaaaaa 112381 acatatatgt tgtaatatct cctgtatttt caaaagcctt ccatgcaaac tctttcaaca 112441 taaatgtatt cccccttatt gtccttgata ataattaggt tacactaaaa atttatttgt 112501 atacttggaa atttatcatc atggttttca tccgggaacc acacttatgc aacagcatga 112561 atgctgtttt acacaagagt ttcatgcatc tatttcttat atcccagagt ctttaacata 112621 aattcattat tcctccagtc aggttttact ttaacccaca actccaaaaa tacctttgtg 112681 ccaaaaagtc cttctatttc cgctcttgaa aggcttccta ttttctttag cattttgcct 112741 tctttgccga ttaaaattcc tttgtgactt tccttttcgc agtaaatagt agcctgaata 112801 tcgagaatgt ccttgtcatc tcttttcttg aaggttacaa cttcaacacc cacaccatgg 112861 ggtacttcat cgctgagaag atgcagaatc ttctctctta taagttctgc ggctattacc 112921 ttttcaggct ggtcggttat catatcgtcg ggaaaatatt taggcccctc cggcaaaact 112981 tttttgattt cgttttttac aacttccacg ctctcatact caagagcaga aatgggtatg 113041 atctgggaaa attccatagt gtccttgtag gccgctatta ttggcagtat ctgttctttt 113101 tccacaaggt caatcttatt tataaggcaa aatacaggag tctttaaatt tttaagctgc 113161 tctataatat ataagtctcc cggtcccggc tgcggacaag ttgcctcgac caaaaacagc 113221 accaaatcaa cctcatttag ggaatccagg gcaatgttaa ccatgaaatc ccccaatttt 113281 gtttttggtt tatgtatacc gggagtgtca atatatatta tctgataatc ctcacctgtg 113341 tctatagccc gtatagtgtt tctggttgtc tggggcttgt cagacataat tgcaattttt 113401 tctccggtaa acttgttcag caaagtggat ttacctacgt ttggcctgcc cactattgag 113461 acaaagcctg atttaaaagc catatactca acctccggtg tcaaaatttt aaaatgtcat 113521 attttaaaac cgccaatttc aaaacttgaa aaaagcattc ggtaaaagct ctccgagcct 113581 aaaaaccgta aattctccat ttttattgcc gcaaatcact tttgtgtcat catcaccaaa 113641 ttctcttagc acctgcctgc atataccgca cggaaaagta tactcatcac tgtcgctgga 113701 tatggccaca gctgctattt cgcgttcgcc ttcggaaaca gccttgaaaa cagccgttct 113761 ttccgcgcag acggtggcac caaagcttgc gttttcaata ttcactcccg tgaagacttt 113821 gccgcttttg gcaagcacgg cagcaccgac tctgaatttg gaatagggag aataggaatt 113881 cttttttata tcttcagcca tagctaaaag ctttctgtcg tccatttttg cctccaaaac 113941 atttcaaaat atattataaa ttatatcttt aacttatata tctttatctt aaaaatattt 114001 ttcccaatat tttattgacc ctggttttaa ttttatcggc aatattttat ttccaaatta 114061 acaaagttta taattccaaa ttcccatttt gttcataatc ccaatttcct atttctaaaa 114121 cttctctcaa tgactctcta tcagtttctt tcaagattta agctttttag tatggcttcc 114181 tgtttttcaa acattttttt ctcccgctcc ggggtatcat ggtcatagcc caaaaggtga 114241 aaaacaccat gggttaacaa aaatatcagc tccctttcaa aggaatgccc gtattccatg 114301 gattgctctt ttgccttttc catggaaatc aatatgtcgc ccaaaatgat tcgtccttcg 114361 tccaaatcaa aatctccctg acttgatttt atcactccgt catacatatc tacaatagga 114421 aatgacaaaa catccgtcgg tttgtcaata tttctttgct catagtttat ctctcttatt 114481 ttttcattgt ccgtaagaat tatacttact tcataaggat actcaaactt ttcatgttca 114541 agacacattt ttatagcttt ttccataagc tcaagaattt catccgtaat ctcaatttta 114601 tcctgtatgt tttcaatgaa tatttccata tgttttcccc tttttgtctc cttccggtta 114661 ttttactaat ctctttttta tcagtctctt tttatttaaa atttttatga agtcatttct 114721 taaaaacact tattccagag actcagtctt cgggttttgg tccttttgct cattctcatt 114781 gttgacatcc tcaacactgt cttctttttt ctttatatca ggatactcct ctctggaatg 114841 aaataccccg ctaaagacct tcataaacgc ttttgctata ctgtcaagat cttttaatgt 114901 aagactgcag ttgtcaagct gcccgtcgtc cagcttgtcc ttgattattt ttcttatgag 114961 ttcttcaatt ttggcttcgg tcttgtcagg cattgacctt acggccgctt caacggagtc 115021 tgccagcata accactgcgg cttcttttgt cgtaggcttt actccatcgt atctgaaatt 115081 ttcctcttcg acattctcca gtttttcggt cgttttggcc ttatgataaa aatatttcac 115141 aagagtggtt ccgtgatgct gtaaaattat gtctcttata ggaagaggta ttttatattt 115201 tttggccatt tcattgccgt catgaatatg ggatgtgatg acaagagcac ttaaatttgc 115261 ggtcatgtcg tcatggggat tgccgctcat ttgattctcc ataaagaaat tgggcctttt 115321 aagctttccg atatcgtgaa aataagctcc aaccctggca agcagagcat ttccgccaat 115381 ggcttcagta gcagcctccg caaggtttcc aaccatcaag ctgtgatgat atgttcccgg 115441 tgcctccata agcagtcttt ttaagagagg ctggttggga ttggcaagct ccagaagcct 115501 taaaggtgta attacgttaa acgtgctttc aagaaacggc aaaagtccaa ttgtaattac 115561 cattgacatt attccgtttg caaacaccag ggcacattct ttaagcaaaa tttcccatcc 115621 ggttttgtac ataatattta tggcggcaac taaaagcaca ttaattgcgg aaacaataat 115681 tcccgccaga gaaagccggt ttcttttatt tgccttggag actataaagg cggaaaaagt 115741 tcctgttaca agggccatat agataaactt gaaatcattg tttatcatca gggatattgc 115801 cacggtcaga acaacattga ccatgatggc aagcctcaaa tcaagcaaaa tggatataag 115861 cattgttgct atgaatatgg gtataatcaa aggagaatac tcatgaaccc atcttgcaat 115921 aaaaagtatc ataagaatga caaccgacag caaaatcaaa tcggttctgt tgtaatatac 115981 ttttttgcag aaattatgca tatacaaaat cagaagcagg gacaagaaaa gtattattgc 116041 cagtattcct cctgcaaaag caaaatcgaa cctgctggtt gtttcaagaa gatttaagtc 116101 ttccaaaacc tgaagcttgt cctcagttac tatatcaccg gcacttaaaa tcttttgtcc 116161 ctttttaatt gtctcaatat ttctggggtc attataagca gcatctcttc ttgcctttgt 116221 aagttcttca tcaatagtcc tgttgggttt taaaacaaaa tccgaaaccg taaggccgac 116281 attcttaagt tcatatttta tttcactgtt aaaaatggcg tcttttagct cgtttttcct 116341 ttcttcaaga ttgtcctcgg ttatatcctt cctcattatg tcattgactt tacttcgaat 116401 tacaacctca agactgttta tatcctcttc accggcattt gatataaggt agtcaatctg 116461 ggcatcctca agttttatgc caagctcgcc gatactctcc acaaacgccg cttttgtctc 116521 gctcagcgca tttgaagcaa gttcttcata gcggcggctg ccggtgattg aagaaatttt 116581 cgacttatag gtgttttggg catcattaat gagaaaaaac agtttatcaa ccagatttat 116641 tacttctata ggtgcattcg gtatatccct cataaccggc gaaacttgcg aagcagcttt 116701 tcttgcattt tcctcagtct ttacagtatt tactatgtcc cttggagaaa tgatgtcata 116761 ttccgatatt gcacccaaag taactctgta ttttctcgga gttgcaccgt ttaaaactat 116821 gagaaatgca agaacaattg ctgcagcggc aataaaaagc ctctgaatgc gtttattctt 116881 gtaaaatgct tttttactgc cgttattgct cctatccttg tcttttgtca taataattgt 116941 tctcctccag tcaggaaagc tgctttaacc ccttttaatt ggtttccttg ctttcctttt 117001 tgcccttttc cttcttttcc ctgtcatatc tttcatatgc ctggataatt ctttgaacca 117061 attcatgtct taccacgtcc atgtccgaca aatggacaaa agaaataccc tttacgtcct 117121 ttaacacttt catgacctca acaagccctg actttttttc ccccggaagg tctatctggg 117181 taatatcacc ggtaataacg gcttttgaac caaaccctat tcgcgtaaga aacattttca 117241 tctgctccgg agtggtattt tgggcttcat caagtataat gaatgaatcg tccaaagttc 117301 ttcctctcat gtatgcaagg ggcgcaactt ctatcatgcc tttttccaga tatttatgat 117361 atgtttcggc tcccatcatt tcataaagag catcatacaa aggacgtaaa tacggatcca 117421 ccttgttttg caaatcgccc ggcaaaaatc ccagtttttc acctgcttca accgcaggtc 117481 ttgtaagaac tatcctgttt acttccttgt ttctgaaagc attaaccgcc atggccacgg 117541 caagaaatgt ctttcccgtg cctgccggtc ctatgccgaa tactatgtca ttttctttta 117601 ttgcatccac ataaaccttc tgtccatggg tcttcgcctt tatctgcctg cctcttgcgg 117661 taaggcagac aaaatccgca gtgaaacctt ttatcttatc caactggttt tcttcagcca 117721 actgaacgaa ataactcaca ttctgctttg agatgatatc accttgcgcc gccatggcaa 117781 taagcctttg aagaaccgtc tgggccttgt atactgcgtc actgtagccc acaactctta 117841 tttcgttgtc ccttgaaata atttttacat taaaagcgtc ctcaattata ttaatatttt 117901 cgtcaaagtt cccaaaaagg ttcatagcat gttcaatcct gtcaaattcc aaagaaactt 117961 ccacaagact ttccaatcat tctcctccat tctcttttgc tactccaata tcctccaggc 118021 attctataat aacatccgca ataatttccc cattttcatt ctcaataaaa ttaacccttt 118081 tgtcaactat cgtggcacct tcggggatat tttccgcggc tttcctgtat gcaatgcctg 118141 cggcattctc ttttgcatct tccaaagaaa tatcggcctc caccaaatca ttttcataat 118201 atctttcaat aacaagccca aagggcagaa caaattcttc acctattgaa agattctttt 118261 ttatttccac cttttcaaaa tctttaaaat ctatctcttt atgaaacaaa ttaatttttt 118321 tcgaaaacaa aaccaaagtt acattgtcct tttttctgcc ggtccttatt ttttcaacgg 118381 ctttaagctc taccggctgc cttccttcat accatgtcct ggcaagaact tccgccatcg 118441 catgcactct ttttgggttg tcttcagctc cctttatcgg tatgcttccc gatacaagaa 118501 gctgtccctt ttttaccgtg tctccctcct tgacctgcgc ctggccaatc ttgacaatga 118561 cggactttat tacgccgtcc ttcttggcca caatatcgca gggcacattc aaaggtataa 118621 tcgaaggacg cttgacaccc tcggccactt ccacttttac ttttgtacct cttaccagca 118681 cattcacata ggaaagcccg tctatgtcca aaatcacacc gtttgcaact tcctcggggt 118741 ttatcctgta tttaagcact ccgggcttta ccccgtattt ttcaaggcat tttaaaatac 118801 cgtccgtttc aatcttttta ttaccgacaa cttcaacact ccacacaaag gatgtcatta 118861 tataaaataa cacaacaaat actgcggcac caagtaaaaa agttttcctg tgccggtatc 118921 tgtttagcaa aaaaggcaag cctctttttt caagtatctt taccctgcag cccgtctttt 118981 ttgccacggg ctttaacatc ttaaagcccc ggatgctgac tttgagggtc attttgctgt 119041 ttctgtccct ttggatatcc cacagcaaaa tttgtcttct ggtacatata ttcacaaact 119101 tctccaggaa atatccttca acaaatataa taacatatcc tcttatataa ttccatagcc 119161 taaatatcaa catttatact cccccgagct actttagaaa ttccagggaa aggatttctc 119221 cgtctatcat aagatcctcc gacgtaattt ctttgataat cagaccttca ccggtaactc 119281 ttatgattcc cttccccgta tttaccctta ttctgctgtt gtcatattca ataattcctt 119341 tgtaattttc tacaataaga tttttgtttc cgaacattgt tatcttcggc aaatccaata 119401 caatctcttt cggcagttcc aacagttccg ccatcttctc cttaagattt attttttgtt 119461 cttcctcttt tcgttttttg gcagatttct ttctttttcc gggcataaat cttctccttc 119521 aaaaaacatt tttcaccagt attaaattta tgcttcccaa aatgtattaa ttccgacacc 119581 caaaaccctt taaaaccgaa atcatttctc aagtataagg tcatttacgt ctccaaactc 119641 aaatcctctt tccctggctc ccttgataat catatcaagg gcatccgcat tgtcctttga 119701 cactgcatgc aaaagcagca ccgcaccgtt gtgaagattg ttcataacct tatcgtaagc 119761 atattgcgga cctcttattt tatccctgtg ccagtcatca taggcaaaac tccaaaacag 119821 attggtatag cccaacttct gcgttatggc aagggttctt tcgctgtatt cgcccttcgg 119881 cggtcttaaa aatttcatgt tgataccgaa tttttcatga aaggctctgt caagccccag 119941 gatttcctct tcaagttctt tgtctgaaag gctcggaagg ctgggatgat gtaccgtgtg 120001 atttcccacc acatgaccct cttctaccat tcttctcacc aaatcctcat gctcatttaa 120061 ataaggccct gttatgaaaa atacagcttt cacattgttg tcccgaagaa cgtcaagaat 120121 ctttgaagtg tagccgtttt catatccttc gtcaaaagta aggtatatta cctttttgga 120181 ggtatcaccc aaatagacgc ccccgtattt tgccaaaagc tccggtgccc cgggatctgc 120241 ctgcggtgtt tcgccgtaac cttttcttaa tattccccag cgcagaacct tgttgctgta 120301 gcccccgctg acaggaatcg cttccacttc cgcaaaaaca tcctcatatt cttcataagg 120361 cacctcgtct atcaccccgt cacttaacat tccggtgatc tccgttgtaa aatccagatt 120421 ctcaaggcgc accgagaata ctccgcccat gtccggcagc ttgagatttt cctgctctct 120481 tgtcgccaaa aatcttattg acaaaagtaa agctaacatt attgttagaa caatcgctcc 120541 tctgattact cttcttttta tcattgtaca agcctcccaa taaaaacact gcaggcctta 120601 aataatgtac ttaaaatata gtacaaaatt taaggcctac aatatttata cattggattt 120661 tccaaaaaaa taacctgttc ttccgctcta aaaaatttta ttataaaaaa ttttttaaca 120721 agcaaaagct ttcaagcttt taaaacaaaa ggaggcaaca aatgcccccg ctctttccca 120781 aacggcggat aaaatatcat aacggagtaa ggaggttgta ctttaacacc gacccgtcgt 120841 ccctgacttt tggtatcgta atcttgtcca ctttggtgac gctgattttg tatccgaaac 120901 tgtctctgaa aatctccacc acgcctccca gcatgttcag cgcataatca agtttttccg 120961 gatcggcaat ggcttttaca acatatgggg ggaatatttg ccttccgttt ataaccatgt 121021 acggatccgc gtatctgatc tccgtcatcg ccacaatgcg ttcaccgttt attgatatgg 121081 cctgcgcctc tgcggctcta agctcattga cgagtttcaa taagtcaatg tcatacactt 121141 tctgataatc atactctccg tcatccaaaa ctatctcaac accgggaccc tgaacatcaa 121201 ccagaccggc aagcattctg gcccttgtaa gctgctcttt tatactttct tcaatctgtt 121261 tattgtttcc cgccgcatcg atatactgcg ccaactgttt ttccaattcc tcgtttctgg 121321 cacgcagatt ctcgttgttc tttttttcct ccagaagttc tttctgaagg tcgtacaggt 121381 tttttgtctg acttgccgac actcttttgt tgctctcgat gcttttatac tgccatgaca 121441 acatgatacc caatataata catattatgg taattgatat atttcttgaa aatttcatta 121501 ctcgaccacc tccaagccgc tgactaaatc atcaatatct ccgccatatt ttggtattac 121561 tatatccttc gccatccgaa cttcaaattt tttgttaaac atttgaaact caccggcaat 121621 aggactgttt acaagcgctt catagagctt tttgggatca cctattgcct ttatttcgta 121681 cgggaccgga taccggtttc tgttgatacg caccgtaggt cccaaacaaa ttatttcgct 121741 tgtagatata atcctctcat tgttaaccga tatggcctgc gctcctgctt ttttaagttc 121801 gtttaaaact tccattattt ccacgtcatg cacaacataa tactcaagtt ttcctccata 121861 ctgctgcgga gcatccgcca aatatacaat cactccgttt cccaccacgt cagtaagacc 121921 tgccacaagt tttgctttct cccactctct ggcaaactca tcgtcatttt ttcgttccat 121981 gaacatttta atgtactcat cctgcttttt aatgttctgg tcgatttcct ccctaagttt 122041 gcttcctttg agcttttcag tttttatttc attttggagg ttctcaatct gataagcaat 122101 agaaggttta ttcttcttgg aattcaaaac gcttctaaac tggactgata aaagtattcc 122161 aaaaaccaaa aacaaaagcg ccaaaatata gcttttatca ttttttttca tatcccagct 122221 tccttttccc cattgtaaaa taaagctttt tacgtttata aaaaacattc aataatttaa 122281 ttctacatta aaaacacact atttcaagta ccaatatata aatttcttat tatataacaa 122341 caaatctcca ataatgatac aataattaaa ttctggttat actaaataaa tcaaattaaa 122401 caattaacaa tctaagttta atatatcgga ggtgtattta atgctttgga gcctgcttat 122461 gccaaagctt gttttcagag acatcagcgt atcctttgat aatgttttgg acgttgcaaa 122521 agcctctagc ggcggacaga gggatgtaaa ttttcttaaa tttcttgtgg acagcaaact 122581 tcttgtacag gaagaagcta ttcttgccag aacgattaca gactttaaag aagaaacata 122641 catgcaaaaa tacaaaaaaa tgcgggatga aagcaccaga cactatctgt gcagagcaat 122701 actgacagaa gaattggaca aactcggaat cgacgtggtg cccgggacag acgtcggaaa 122761 catgaacata cttcgggcca atgcaaacta tgacattgcc gcaaaagact taagctttat 122821 catggatata ggctttaccc ccgcaagaaa cttcttcaga ggactcacag acacacgggt 122881 aaaatattat ctcgttacca catattttga cgactacatg gacgacataa tattctgctg 122941 cctcaaaaga gcagatgatg aagcttttct tgatgccgta aaagattacg aagacggttt 123001 taaaatgttt attcccgaag attctttatc cgcaggaacc gaaaattttg ataccgacac 123061 ccttccttaa aactattcac aatcttaagg gcaaaatttg ctccgatttt ttcagcatta 123121 attttctcaa cctttgcttt tgtgttgttt tttgtggtat atattaaatg ttagtatagt 123181 tacaagcaag cggaagggtg gttttaatgt tctatcagat aaggtaccaa acaggtgaaa 123241 ttgaggatat ggtcgcggaa atgaaaaaag gcaacatccc gtgcatggat gttgacaata 123301 tggatgaatt caactgggtg gtaaagaaac tggaagaata taatatttac cttgcgaaaa 123361 atattccttt tgacaaaaat gcaagggaca gggtaaaaga gccggaattt gaattcagag 123421 cggctttttc gtcaagcaaa gactcggaag acaatcttat gtatattgac ttttattttg 123481 agccttatgt ggaaaaggac tatgatccca tattcggaga ctgataatct taaaggggcg 123541 tcaaagcccc acttttttaa ccaaaacgct tgtaaatcgt ctgttatttc tgacttatct 123601 ctcttacttt attgacgtag aaattcgtaa gttcttctgc aaattcagcg gaataacttt 123661 cgcttttaat tctgcagacg ggctgttcgg catcaggcaa aaccaatacc catccgccgt 123721 ctttgaatat ctttactcct tcaagggttt caatgctttg tccctcattt tcctggataa 123781 tctgtcttat tacttttcct tttacgttcc acgaacattc aacctctttt tcgcttacat 123841 agaaatccgg tatcatgttt acaaggtcgg aaagactgta gttttccgat ttcatgaaat 123901 caagaatttt caccagtccg gcaatggcat caaaatgcag cgtaaactgt tcatacacat 123961 tttcctttgt ttcgttgcca agcatcttgt tcataatatc ctgaggagac gttttcgttc 124021 ttattacctt gccgttgttt tgctctgcca gtttgtccac aaccgagctt gtggaaatcg 124081 gcaccaccac tgttccgccc tgaacggttt taaacacaat caatgaaata agggccgtaa 124141 acatgtcatc cgatacaatc cggccattat tgtccaccag catcattttt tcagaagtat 124201 cttcaattga cacacctaaa tcgtagtttc ccatttttat catgtcggta aaataggtca 124261 tttccgcaga tttattgcca tttctcattg ttttggcatt acgcaaatca agcgaagttt 124321 tttctaccgt acagccaaaa gtttcaagca aattgcccac tgtttcgaga atgaaaccgg 124381 acaaagaatt aagagctata cgataaccga agtcttttga ccgggtgttg tttattatat 124441 ttctcaagta gtatttggta tagtcaggta ttacttcaac atcttttatg gcctctccct 124501 cacatctgct gaagtcttcc ctctggaaag cattctcaat ttttctctcc acttctcttt 124561 ttatattgct gccgtttttg tccaaaaagt ccacggtaag ccggccaaaa tttgtgcttg 124621 acgtgcttat atgaattcct ccgtcagctc cgtaaaacct tactgcggat cttgcaactg 124681 gcaaatggag gactccaaag tccaaaacct taagtcctgc ggaaagcagc cccgacataa 124741 aagacatctt cagcattttg gcagcggccg agtcgtcaga gcttacccct attttaccct 124801 tgcccttaaa aatagctccg taggcagcac caagctttga agcatattcc ggagtaatat 124861 ccacatttat ttctccggca actcccctga aaccaaatat ggaacggaca aattttgaac 124921 cccatacaag gtttgaattt acctcagttc ctccctccac aatcttgtta ggccatattt 124981 taatgctggg ctttatcacc gcatttttcc ctatttgagt atcatcacct ataacggaat 125041 tttcaaaagc aaaaacccct tctttgatat tgaccttgct gcaaactacg gtacctctca 125101 gttgggtatt ggtttcaagc acgttgtttt tccaaagaat gctcctcttt ataccactcc 125161 tctcaccaat aatattattg tctcccaaaa cggaataact gccgataaca gaatctttct 125221 tgatccgggt atttgctcca ataacacagg gctcttcaat aacaacgttt tcctctatta 125281 cggttccttc tcccacccat actctgtctt ttattttatt tcccggtatg tttattttca 125341 ctttgccgtc cagaacatcc atatgggctt tgctgtatgc catgaggtct cctatgtcgc 125401 accagtattc atcggtgatg tatccataca tgggtttatt ttccttaagc agcataggaa 125461 acaaatcctt gctgaaatca aacatttcat ttttgttaaa atattttaaa acctcaggag 125521 acagtatata gataccggta tttacagtat cgctgaacac ttcgccccag cttggctttt 125581 ccaaaaacct tgttattctg ccgttttcat cggtaacaac aacgccgtat tccaaaggta 125641 tgtcgacctt tttcagtacc agcgttgcca tcgacccttt gctgtagtgg tactctaccg 125701 cctttcccaa atcaatatca gtcaaggcat ctccacttat caccagaaat gtatcatcca 125761 aaaattcttc ggcgtttttt acacttcccg ccgttcccat cggtttatct tccacataat 125821 atctaagatt tataccaaaa tcacttccat ctccaaaata gtcctttatc atatccggta 125881 aatattgcaa agtaactgca atatccgtaa atccatgttt tttcagaagt tcaataatat 125941 gctccataac aggtttgttg acaacaggta ccattggttt tggcctgtta cacgtaagcg 126001 gtctaagtct ggtaccttct cctcccgcca tgatgacagc tttcattcta ttcatccttt 126061 cataaatttc ttgctgaact ttaaaaagca tacagatttc ttgactgtaa ttttccttga 126121 ctataaatct cgtttttata tttaaagctt ttgtaaaagc ggcaagttta attcgtttta 126181 attttaatca gctttgttat tttttgtttt ctactttaaa atcttaaccg ggctctttta 126241 ttatgctcct ttgagcatga aatatttcat attacctgac tcgactttaa ataccagtat 126301 tttttcaaaa cattcatcaa ataataaaaa accactgcag gttatgtttt ttaaacatca 126361 cctgtcagaa attattaaca aaaaatataa tgtttattat gaacggagga atggtcatgc 126421 caagaagcac caaagtaaac aacgattata tgtccaacgg tattaccata aagcctgctg 126481 ttcccaccgc aggagagaat ttaaccgtca tgtacgacgg tcttctttcc aaaagcggtg 126541 catcccatgt atatgcccat gtaggttttg acagagactg gaaacatgtt tatgactatc 126601 ctatgaaaag gacttcaata ggatttgagg caacaatacc ggttatggaa gccgacaccc 126661 tgaacatctg cttcaaagac tgtgcaaaca actgggacaa caactcaggc gcaaactata 126721 ctttcgatat atccaaataa aaaccccgtc ttccattctc tcctaaagtt ttaaaatcag 126781 gcagggagga caatctccct gcttttttat taaaattttc ataaagcaaa gtaaaaaagc 126841 aaacgtaaaa aacccgatgt cttaaatttt agttatctgc tgtaatgccg gacggtcagg 126901 aacaatttca ttctttgctt aatataataa aggaaggagg tactgccata tgatgttcta 126961 taaccgcaga atgtacataa acaggtatcc cgtaccacaa aaccaaatcg ccgcaaacga 127021 ttcggaagaa gttcaaaaag acagtgaaac aaaaagagat gataatacgg aagacaataa 127081 aaaattgata ctcgatgcct tcaaaagcat taatgacact cttatggaaa acattaaaga 127141 actcaaccgt ttaatcagca aacttgctga aagggttgaa aatttggaaa accaaatatt 127201 tgcgctggaa tctcaaattg aatctgagaa atcaggcaga aaccaaatac cacagtcaga 127261 aatttcaaac atcacaacag agctggagct tctaaaaaga aattcttccg tcatacaacc 127321 ggaagaaaac aaagaaccca gcaacaaacc gataatgccc ggatgcggat tttcggcaat 127381 taccccggaa tatctaagaa gcctctataa aaggtgatgt tgtttaaaaa gtcttgaaaa 127441 agactttttc ttttattgat taatttctaa catccagcct gatttttaaa acaaaaatat 127501 aggtaacata aaactattaa atgaatacta tgtatcagaa gcaaaaatta ttactacaat 127561 aagaaagggg tcttgttttt atgaaatatc aggaggattt cttcggaaca aaaactgaac 127621 ttgcagattt cgtaaaaaaa gtggttcctg aactgttcgc aggaaaattg acagtagaag 127681 gaaaaaatgt agtaattcct tccgaccgtc aagttgatta caaaatcaag tacagtgaag 127741 acgaagaagg cgcagctgtc actcttaaaa tttcctggga ttttgaaacc gcaaccgagg 127801 aagaggaaga ggaaggaata gagctggatg tagaataatc ggctttttcc tggaaagggg 127861 gttttccccc tctttccata acttttttca tttacagaat tttatttaca gcaggctcct 127921 atttattttt ttgaaggagg atgtatacca acatgcctat aaaccatgaa cccctttttg 127981 atgtgctttc acaatatgat ataaaggtcg tctcgataag aaatgaaagc tacaaggata 128041 aaaaaggtgt ttggtggata caaacccctg atgaatacaa aattctaaaa aagatatcaa 128101 attcggaaga cacttttaaa tatatattga gtgctgcgga gcacctaaga aaaaacggag 128161 taaatattcc tgctgtatac aaaacaaagg acggaaaaga ctatgtgaat attaacggaa 128221 cctgctacgt tttatatgag gcggttgaag gcaaaaatcc ttcatataat tcacctgaag 128281 acttcagggc gattgtcaga gaacttgccg gatttcatgc cgcatcagtg ggattttcgc 128341 ctccggacaa cacaaaacca aaaattcatc tgggtaaatg ggttgaacaa tacacagaac 128401 aagtggaaga catgaacagg ttctatcaaa ccgaacttga gaaaagcgaa aacgacagaa 128461 taggaaaagt aattatcgaa gagtttcccg ccttttatga aagggcaaaa caagcgattg 128521 aaggattgaa gggaaaagaa taccaagact gggttgaaaa agtcaaaagc cggggcgggc 128581 tttgccatca ggattttgca gctggaaatc ttttaaaaaa tccttcggga aaaatttttg 128641 ttctcgacac ggattcaatt accatagaca ttccggcacg ggatataaga aagctcctta 128701 acaaaatcat gaagaaaaac ggaaaatggg atttggaaat tcttcgcaag tttatacgaa 128761 tttatcaatc agaaaatcca ttgagttttt ccgaatggac ggttgtaaag ttcgacctca 128821 tgttccctca tctgttcctg ggagctatga ataaatttta ttataaaaga gacaaagaat 128881 ggagttttga aaagtatctg aaaagaataa atgaaatgac cgctttggaa aagaccatta 128941 cacctgtttt ggaaaacttc gactccattg tttatgaaga gattaatcaa aggaaggact 129001 gagaagcttg aatgaagttg gcaaaaaccc aaacatggat ttgagtaagc ttgcaagttc 129061 tgtattggaa gagtatggaa tcgaaccgga aaacattagt gtagttcaaa gtgcaaatat 129121 aaaaaccgta tggagaataa aaacgaagga ccgtgaactg tgtctcaaaa gattgaaaca 129181 tccattagac aaagctctct tttccgtaaa cgcccaggat tttatataca atcatggcgg 129241 aaatgtcgcg ggaataatcc gggataaaga aggaaatctt attcattctt tcaacgacca 129301 gctgttcgtt gtatatgaat ggctttacgg aagggatttg tcctttgtca atgctgatga 129361 cttaaaatcc gccctgcacg gccttgccaa atttcatatt gcgtcaaagg gttatgtcgc 129421 cccggaaggt gccaaagtct cttccaagct cggcaggtgg cctgaacagt acaaatccat 129481 ggcagacaaa ctttcttcct ggaaagaagc atccctggga aaacctgctt cagcttctgt 129541 caatgcttat ctcaaaaatg ttgacgaaat gcttgatatc tgccatcggg ccatggagct 129601 tttaaatgcc tcaaaatatg ccgagttggc aggtgaaaat tccaaatcgg ctgttttatg 129661 ccatcaggat tacggcaagg gaaatgcact ttttacagac aatggtgttt atgtcataga 129721 tcttgacgga gtaacctggg accatcctgg acgggatctt cgaaaaataa tcggcaagct 129781 gtcggagaac agaggagcct ggtctttgga tcaaatcgaa aaaatccttg actggtacag 129841 cgaaataaat cctctttcca ccgcagacag ggaacttatt tatattgacc ttatgtaccc 129901 ccactggttt tttggccttg ttaaaaacat tttcaagaac aataaaagcg aaagtccgtc 129961 aaagattgaa aaaacagcaa ggctggaaac ttccaaagta ccattgcttg ccgaaaagct 130021 tcgggatata aaatcgcagg gctaaaaagg ggggtgataa aatgaaaatc gccttgatat 130081 gcaccgagaa acttcccgtt cctccggtcg cgggaggcgc ggttcagcta tatataagcg 130141 aaatattgcc atatttaaaa gaacgtcaca atataacagt tttttctaaa attcatcccg 130201 gactttcccc ggatgaagtg gtcgacaatg taagatatat ccgggtaccg gccgccaatg 130261 cttcgaagta tgtaaagaat gtaaaagacc tactggatga gagttttgaa ctgatacaca 130321 ttttcaaccg cccgaagtgg gtactggact ttagtgaaaa acttccttcg gcaaagttca 130381 gccttagtct tcacaatgaa atgtttttgc cggataaaat accttatgaa aaggctgttg 130441 aatgtataaa cagagttgaa ttcataaaca cggtgagcaa gttcatagcc gacggtgtaa 130501 aacagcttta tcccatggca gaagacaagt taagagtggt ttactcggga gtcaacattg 130561 aaaaatacaa gcccaactgg tcaccggaag gaatttgcaa caaagagctt ctgaaaaaga 130621 agcttggaat agaaaacaag cgggtaatac ttcatgtcag cagattaagt ccaaaaaaag 130681 gtacccatat agttctgtct gccatgaaaa aagttatgga ctgttttgat gatgttgctt 130741 tggtaataat cgggagcaaa tggtacggta aaaatgaaga agatgattat acaaagcaat 130801 gcaaggccct tgcagaacaa ttaagcggtc cggttgtttt tacaggcttt attcctccgt 130861 ctgaaattcc gccttattat aacgtgggtg atatatttgt atgtgcatcc cagtggaatg 130921 agcccctggc aaggatacat tatgaggcaa tggctgcggg cctccccatt attacaaccg 130981 accggggcgg aaatgcagaa atattcgaag acaatgtcaa cggcattata ataaaggact 131041 acaaaaatcc ggactctttt gccgacaata taatctatct tctgaacaat cctcatacag 131101 ccctggaaat gggcaaaaaa gcttttgagt ccgcactctc cagattcacc tggaagagag 131161 tggcggatga ggttttggct ccaatccaaa acttcgacca aagaataact gttaatgaca 131221 ataaaacaca gagtggcctg gcaaaagaaa atataattga agaagatata atgaaagaaa 131281 ataacgatga aaaagcaacg gaagaaaaaa gcacagaaga gattgaaact tttttcgacg 131341 acacaaattt ttaaaataaa gccggataaa ttctttaagc taagaaagca cagatttcgg 131401 ctttcttgac aagggaagtg attttatgaa agtaatgctt gttacaggcg gagcaggttt 131461 tgtaggaagc aactttatac gcttttttct cagaagaaac aaaaatttta ttatcataaa 131521 catggataat ttaagctcca catcaaacct ggaaaacgta aaagatttgg aaaagtcgcc 131581 ccgataccat tttgtaaagg gcagtataac aaaccatgaa cttgtaaact atgttattaa 131641 aaggcataga cccgactgta taattaattt tgcatcagaa tcaagcctgg ataattgcgc 131701 aaacaatccg ctaaatttca cacagaccaa cgtcctcggt acgcagacgc tgcttgaaag 131761 cgcccgttat ttctggggaa aaaacaaatt tcagggcaac ctctttattc aagtgtcaac 131821 cggtgaggta tatgggagca caccggcaaa tgatgtattt ttcagtgagg aagcaccgct 131881 tttgtctgac aatccgtttt cagcttccaa agccggagca gatatgctgg taaaatccta 131941 tacgattacc tatggttttc cggcaataat aacccggtgc tgcccaactt acggaccttg 132001 tcagcatatt ggaaatttta ttccgaaatg cataataaat gcgctttcgg ataaacccat 132061 tacggtctgt gaaaacaaag tgcgggagtg gatatatgta ctggaccact gcatagctct 132121 tacaaagatt ttgttttacg gccggacagg tgaaatctac aacatctcct ccggcaacga 132181 aatatcggac tttgacgtgg caaaaaagat tctcggactt gtcggcaagc ccgacagcgc 132241 aattgaaaag gcagatgaca gttctcttcc aaccaaaaga tgtattctta acagctacaa 132301 actgaaaagc aatttgaatt ggagtatcaa gttcaaacta gaagaaggat taagggaaac 132361 catcttatgg tacaagcaaa atccggatag gtggaaaaat gtagaattat aaaagtcaga 132421 cctctgtaaa aattttaatc ttaaataaaa ttttaaaacc ccatccgatt tcagatgggg 132481 ttacaataat taatacgata tttcatggta gtagtatcta tcgggcctta caacctcttt 132541 gtaaagtttc aatccttgca ggttaaaacg tctcagcagt tctattgcct ttggaagctc 132601 attttcttta aatcttactc ctatattgca caaatctatc attatttctc tgggcatgta 132661 agttatttca caggtcttca taccctcgct cttcattctg tgctccaaaa gaaaagcatg 132721 tgttcttgac tccaagccga cataataata catccaaacc actccacagg cagtaaaaca 132781 cacagaactg cagcttattg cagttctgcg cgttttatgg cttattcact tctttgatcc 132841 aacggattcc atttctgatc cgggaagaac ttcgtcggga aaggcgtctt tgttctgtca 132901 ttaaaagtct tgcagttctg tacggccgga ttgacctgtt ccggcggaac cgggcaatat 132961 ccgtaagaag gaataagaag ctgtacaacg cactcacatt taacaataaa gaatacaccg 133021 atatccagag aaagtactcc tgtattggga ttaatcacgt cattaaaggc ttcggccaaa 133081 gcttcaacct ttatcatggt tccgtccgga tccttggtct tggtcggacc ctcccagaag 133141 tcatcattgg acttgattac tccgacctgt gcaatgcagg acgggcagta gatttcattt 133201 accgtaaggt taaacgttgc ctcatcggtc tgggaaagtt gttcagaacc gtcagaatag 133261 tgtattttat accttatctt tacaaacagt ttcagtttct tgtaaccggg ttttgttaaa 133321 gaatccgttt ttgatattac ctttacttca acaatgtcaa agtcagttgc gccttcaaag 133381 gcaaagacag aatggcagtg gtctccgcct tttttcaagc ataccgttct tgttacgcag 133441 tctctcaggg caacctggtc aaataccttt ggcacctgta cgcataccaa ctcagttggt 133501 ggcggaaagc attcaggatt caaaatctga ccggcctcaa ttttaggtcc atgtgcatgc 133561 atagcgtaat cctcctttta acataattcc ttataccgat ttacagattt atagttccta 133621 agttatttat ccatcttttt atcgtaagat ttatctacac tatcagtata ttaaaaaata 133681 aaaaagggtt acactttgcg cgcattatgg ttttaaagta aacgtaaaac taaacgtaaa 133741 actactggac ttatgcaaaa ttgcataaaa aaactgccca aaaaagggca gtatttttta 133801 tgcaaggata atatcttttt atttttaaga cattatcttc ttctcggctc cacaataagt 133861 ttcattgctg ttttttgaac gccgtcaatc tcaacatcgg taaaagccgg gatgcaaatc 133921 agttcaattc ccgatggggc aacaaaacct cttgctatag ctatcgcctt tatagcttga 133981 ttcaacgctc cggcaccaat tgcctgaatc tcaactgtcc cattttctct cacaaagccc 134041 gccaaagcac ctgctatgga atttggattg gattttgctg aaacctttaa aacactcatg 134101 gtttttttac cccctttttt acatacaaaa accacgacta aagacaagtt aactctgaca 134161 aaatatatcc aagcgtatat taatttaatt ctacataaaa tcagaaattc ctctttttta 134221 gttaatattt agtaatattg cagcactgca aaactttttt aatcaaacct ccagtatctc 134281 atatattctt tctataccgg tcgtcttacc ggttttttca tcaatctcca aatacacggc 134341 attaaactga acccggccgg tcgccacttc aaacctcaca ggcatatgcg tgagaaactt 134401 ctgaattaca atttccctgt tcacacctat aatgccgtca taaggtcccg tcattccaac 134461 gtcggaaata aatgcggtac cgaaaggcaa aattctttca tcggcagtct gaacatgggt 134521 gtgggttccc aacacacaac ttactctgcc gtcaagatac catgccagcg cacatttttc 134581 cgaagttgcc tctgcatgca tatccacaat gattaccttg caattgtttt tcagatactc 134641 caattccctt tccgcagcct taaacggaca gtctatgctg tccatgtata ttcttcccat 134701 aaggttaagg atacctactt tgccgttttc gccacaaata acggtcgagc ctcttccggg 134761 aagttcaacc gggtagtttg ccggcctcac aatattgctg tcggaatcaa taaaattcat 134821 tatttctttt tttgaccacg tatgatttcc caatgttatt gcatcaattc catatttata 134881 caattcctgg gccactacat aggtaattcc gcttcctcca gccgcattct caccgttggc 134941 aatgcagaaa tctatctgcc tttccttctt cagtttctgt accatttctt tggcggcttt 135001 tctgccagga ttgccaaaaa tatcccctat aaacagaatt ttcaaatcat atcctccatt 135061 tctaacctat ggcaacgcaa tatgtactta attttattct atacccgtaa actcttaaat 135121 aacacaaaaa gcgtgagtcc acgctttttg tgcagaaaat atccaaaatc tatttagcat 135181 attctatata cctggtctcc ctgataacat tcacttttat ctgtccggga taatcaagct 135241 cattttcaat ccttttcaca atatctcttg caatcaatgc aatatctgaa tccgatacat 135301 cctcaggttt caccatgata cgaatttctc tacctgcctg aatagcaaaa cacttatcaa 135361 caccgtcaaa agaattcgca atttcctcaa gcttctccaa tctcttgata tatgattcaa 135421 gagtttccct tcttgctccg ggccttgcag ccgaaataga atccgcagct tgtacaagca 135481 ccgctatgat ggaggtggct tctacatcgc catggtgcga agcaattgca ttgacaactt 135541 cattggattc tttatacttt ttagcaatgt cagctccaat cgtaacgtgt gacccttcaa 135601 cttcatggtc aacggccttg ccgatatcgt gcagcaagcc tgccctcttt gcaagattaa 135661 catcaactcc aagctctgcc gccatcaaac ccgccaaacg agccacttca atggaatggc 135721 tcaaaacatt ttggccatag cttgttctaa acttaagctt accaagcaat ctgacaatct 135781 caggatgcaa tccatggact cctgtttcaa atgtggcatt ttccccttcc tggcgaatag 135841 tgttttcaac ttctttcctg gctttttcaa ccatttcttc aattcttgca ggatgaattc 135901 tcccgtcaag aatgagcttt tcgagagtaa ttctcgctat ttctctcctt attggatcaa 135961 acccggaaag gataacggct tcaggcgtgt catcaataat gaggtcgatt cccgtaagcg 136021 tttcgagggt cctgatattt cttccctcgc ggcctattat tctacccttc atctcatcat 136081 tcggaagtgg aacaacagaa acggtaactt cagatacgtg atcagccgca catttttgaa 136141 tcgccatggc aataatattc tttgccctga tctctgcctc ttctttagcc tttgcctcaa 136201 tgtccttaat taggattgcc atttcatgtt ttacttcatt ttcaacattt ttcagcagga 136261 cttcttttgc ctcgtcaaca gacagcccgg atattctttc aagctcggcc acctgttgtc 136321 tttgtgtctc aagtgtctgt tcataaagtt cctgaatctc tttcgtcttt ttattaagaa 136381 gttcttcttt ttgttccaag gattcgactt ttctgtcaag agcctcttcc ttttgaacaa 136441 gtcttctctc cagacgctgg atttcatttc ttctttcctt aatttctcta tcgagctcca 136501 acctgctttt atgaatctct tcctttgcct caagcagtac ttcccttttt ttagcttccg 136561 caattttttg agcttcgctg attattcgct ctgcttcctg ttcagcactg ccaatttcgg 136621 cttctgcttt tttctttcta aattcaatac cttttcggta acttattact gaagcaataa 136681 ttgaagcaat tattgcaatt actatacctg tcagcaatcc accaagataa gctatagcac 136741 acacctcctt tattcagttt tcaatggtca gttccaaata ttcaaaatcc ataagcactt 136801 acttacgtac tttttcattt taatcttttt tatattttat gtcaagaatc aattaggccc 136861 gttagctttc ttctccggta acaacactta ttccgtcctt catttccacc cgataccatc 136921 gatctgccat ttcactgaga tgcctgttgt gcgttaccat tattacctgc ctttggaaca 136981 tatgtgttac ctgttttaag aactctgcca catgggtaat ataatcatcg ctcacatgtt 137041 tggcaggttc gtccaaaata atcggacctt taatttccag gttgctgcat tccagcatgg 137101 caatccttat ggcgagggaa attatatcaa tcacccctcc gcctcttgct tcctgcggtt 137161 ttgtctttat ctgcgtccca ccgaagttgc tcacaacata aaactccgcc tcaggtcttc 137221 ctcttacctc atttatttca attttaaact cgatattgga gtcaaatatg tactgaaggc 137281 aatgagttac caatgattca atctgtaccc ttgactgttc tcttgcgtat tctgacacct 137341 tttgaagaag aagtctcact ttctccagaa catctatgtt ataaagtgct tttctaagct 137401 gcgtccccaa tgaagttttc tgctccgtaa gctggtccat cttacccttt tgattgtagt 137461 aatacatttt tgccttttca tatcgttgtt tgaagttttc aatattactg cggtatctcg 137521 caagggtacc tggctccaca ttttcaacct gccttccttg tttaattctt cttaattcct 137581 tcttattttc ttcttatccc tttcttattt ctccattcca cttctccatt ttattacttc 137641 atttttgcct gaagcttcgc cgcttttacg gtatttttca tcagcatggc aatggtcatc 137701 ggtcccacac cgccgggtac cggagttata gccgatgcca cgcggcttgc cgactcatat 137761 tccacatctc ccacaagctt tttgttttcc agacggttaa tcccgacgtc aatcaccact 137821 gcgcctggct ttatgctgct tccctttatg aactcgggtt tgccgacggc tacaacaagt 137881 atatcggctc ttttgcacac ttcatcaata ttttgcgtcc tggaatggca cacggtcaca 137941 gtgccgtttt gagccagcaa aagcattgcc atgggctttc ccacaatatt gcttcttccc 138001 acaacgacac attccttgcc ggtaatatca ataccgcttt cctttatcag ctccatcaca 138061 cctgccggcg tgcacggaag aaaatcagga tttccaatca taagttttcc cacatttacc 138121 ggatgaaaag catccacatc ctttgacgga tctatggcgt aaataacctt ttcctcatca 138181 atgtgcttcg gcagcggcaa ttgcacaagt attccactga ccttgtcatc tttgttaagc 138241 ttgtgtataa gctcaatcag ctcctcctgg gttgtgtttt cctcaagggc atattcaaag 138301 gactcaatac ctatttcagc acaagccttt ttctttgaat tgacatatac ccttgatgca 138361 gggtcattac ccacaattat tacggccagt cccggattaa tattgttctt ttttaaatct 138421 tcgacctcaa tctttaactc ttcctttatt tttgttgaca attcttttcc gtttaatact 138481 ttagcctcca ttttgaccaa cctttccaaa acaatttgtt gttaatacag ctttcaccaa 138541 gaatttcttc aactttatca ttttatttta ttcttattaa cttgtcaaat tctttcaact 138601 tatcttgagc tctttcttct gctttttccg gcttttttta attttctttt tgagctgtct 138661 tttttcaaat tgttttttga aagattagcc ggaggcttta tgaggcattt cctgccgtaa 138721 ccgattaaat cctctctgtg ggcaagtttt aaagcctcat acaccagctt gtagttttcc 138781 ttccttctaa attgcaagag agccctttgc attgcctttt ccttcggcga ccttggaaca 138841 tacacctttt tcatcgtcct tgggtccagc ccggtataaa acatgcaggt ggacaatgtc 138901 ccgggcgtgg gataaaaatc ctgtacctgc tgaggcgtgt aatttatatc cctcaggtac 138961 tcggcaagct ctatcgccgc attaaggtcg cttcccggat gacttgaaat caaataggga 139021 acaaggtact gttccttgcc tatttttctg tttatctcat aaaacttttt gacgaatctg 139081 tcatacacct ccctttgggg ctttcccatc ttctcaagca cccggtccac cacatgctcc 139141 ggcgcaactt taagctgccc gctgacatga tgccggcaaa gttcgacaaa gaaatcgtcg 139201 tttttatcca gcatcagata atcatatctt atacccgaac gaataaaaac cttttttatt 139261 tccggtattt cccgaagctt tcttaaaagc tccaggtatt cgctgtggtc aactataagg 139321 tttttgcaag gcttggggta aaggcattgc ctttccttgc acgcaccgga aatttcctgc 139381 tttttgcagg ccttgttcct aaagttggcc gtgggtcctc ccacatcgtg aatatagcct 139441 ttaaagcccg gaagccatgt aagctttctt gcctcattta ttattgaagc ctggctgcgt 139501 ttttgaatta tcctgccctg gtggaaattc aacgcgcaaa aggaacaacc gccataacag 139561 cctctgtggc ttgttatgct gaactgtacc tcctctatgg caggaactcc gccgtctttg 139621 tcatagacag gatgataagt cctttcatac ggaagagaat atatcctgtc catctccttt 139681 tcggaaaggg gataagccgg cggattctga gccacaaacc tgtcaccgtg aggctgcaca 139741 agaacgcttc cggtgtaagg gtcctgctca ttgtactgaa tcataaaagc ctcggcatat 139801 tttcttttgc tcgtggacac ctcttcaaat gacggaagca gaatataacc tttttccggc 139861 ttgtcttccg aattatcaat aaattttctc aactctccat gcaagtcctc ttttcttgcc 139921 agaaaagcgg ttccccttac attctggatc ttctttatcg gcactcccat ggaaagatac 139981 cgggcaatct caagtatcgg tttttctccc attccgtaaa ttaaaaggtc agctttcgag 140041 tcaactagaa tggaacgtct gaccctgtca tcccaataat cataatgggc aaatctcctc 140101 aggcttgcct caatcccgcc gataatcacc ggcacatccc tgaaaagctg ccgcgctttg 140161 ttggtatata caatcaccgc cctgtccggc cgtctgtggc tttttcctcc cggactgtac 140221 aaatcatcgc ttcttggctt tttactcgca gtataatggt ttaccatgga gtctattact 140281 cccgatgata taagcacggc caaacgtggc tttcccaatg ccagaaagtc atcgtccttt 140341 ctccagtccg gctgggcgac aatccccacc ctgtagcctt cactttccaa aagtctcgtt 140401 attatggcat gcccaaagct gggatgatcc acatacgcat ctccgctgat ataaagaaaa 140461 tccagttcat cccatcctct gtttttcata tcttcccttg ttataggtaa aaaagccatt 140521 gctccactcc cagttcacca tgctatctca ataaattatc caattaatat cttttatact 140581 attcttctaa tattttttac tattcttctg ctattcttca cttttcatat tcatttcgtg 140641 caactgctgt tttgttataa gcacctgcct tggtttgctt ccctcaaagg gaccgacaat 140701 tccccgggcc tccatctggt caattatcct tgccgcccgg gcatatccca ctttgaactt 140761 tctctgtatc aaggataccg acgcctgtcc ggcatcaacc acaagctcta ttgcctgggg 140821 aagaagctcg tcattgtcac cggggtcgct gtttttgttt tctttttcac tgtttatctc 140881 gtcaataata ctttcattat attctgcatt cccctgggat tttatatact ccacaactct 140941 ctcaacctcg ccgtcggata caaaagctcc cttgaccctt ataggctttg acgcacccac 141001 aggataaaag agcatgtctc cctttcctaa aagcttctcc gccccggcca tgtcaattat 141061 ggtcctggag tccacttgag aagacaccgc aaatgcaatc ctcgaaggta tatttgcctt 141121 tattacgccg gtaatcacat ccaccgacgg tctttgggtt gctatcacaa gatgcattcc 141181 tgccgccctt gccatctgtg caagtctgca gatcgcatct tcaacatcgt ttggagccac 141241 catcatcaaa tccgccagct catcgattat tataacaata tggggtaaaa tttccgtctc 141301 gccgtttttg gcaagcagtg cgttatatcc tttaatatcc ctgactcctc tgtccgcaaa 141361 cagcttatac ctgtttacca tttcctgtac ggcccagttc agcgctcccg cggccttttt 141421 cgggtccgtc accacaggta taaggaggtg gggtattccg ttgtatatac caagctcaac 141481 aacttttggg tccaccatta aaagttttac ctcatttggc gatgccttaa acaaaagact 141541 tataataaga ctgttgatgc acacactctt tccggagcct gtggcaccgg caacaagaag 141601 atggggcatc ttggcaatat ccgccaccac attctgcccg gatatatctt ttcccaaggc 141661 aaaagcaagt tttgagttgt attctttaaa ttctttggaa tccaaaacat cctttaaaaa 141721 taccgggacc acttctttgt ttggaacctc gataccaact gcggcttttc cgggaatagg 141781 agcctctatt ctgactcccg atgctgcaag gttcagggat atatcatcag agagacttac 141841 gattttgctg accttcaccc cgggactggg ctgaagctcg tagcgggtaa ccgcaggtcc 141901 cacactgaca tttacaacct ttgcatccac accgaagctt ttcaaagtct cctcaagttt 141961 ctttgcaccc tttaaagcag agtttctata gttttcggca tttccgagac tcatcttgtt 142021 gtcatccaaa agtcctgtat ggggatacct gtattcaaca ttgtcctgca tctttgatga 142081 gatttccaca ccgacattgt ccagattttc ctcagctttt gcttcggaag tgccattttt 142141 cttaagatcc tgcacaataa aatccacttc atcgttttca ggcttgactt catcgacttt 142201 agcatcttta ccggtatcat cagacgattg ggaagtattg ccgtctgccg ttttgccgcg 142261 cccgctttcc ctggcggctt tctttttttg aaatccagaa tcttcgaaat ctttttgccg 142321 ttcattacaa catcaatatc aggttccgtt tcagtttcgg gttcagtttc agtttcattc 142381 tcaggctctt cttcctccct aagtttttct ttaagctcac ttttcgttat tttaaaacgg 142441 ttttcaacct ttgcggctat cgcggcaaca tcatttttta ttcttaaaaa cacacccgca 142501 attgatatgt ctgtgataat aataatatca atcagtgcaa tggtggtaag aattattacc 142561 gtaccgagat ttttaaagag cagcaggaaa ggtatgctga tgattcctcc cagcacaccg 142621 ccgccatgca tggcagctcc gtcattaaaa aactttttta tgcattcgac ggctcctttg 142681 tttatataat cctgctcgtt gtaaaacaat gtctgaacca ttgcgctcat tataagtatc 142741 aagacaaata tatatctaat tttcgaattt accctttcat tgttctttct aaatatgaca 142801 agtatcgaat aaaaaattat aaacagcggc acaacataac ccagccatcc cataagccct 142861 aagatcaaag ttttgatgaa agtaccgaat atgcctatgg aatcctccgc aaaaaggcca 142921 aacactgtca gcaatcccaa tgccagtaat ataattccga ctatctcatt gttatatttt 142981 ttaatgccgc ttttcttttt ggtaagcttc ttcttttgtg ttttctttgc tttcaatttg 143041 acacccccac aaattccccc tctttagctg tcaaacaaaa taatacaagc tatacttaat 143101 ataacacaat gaaagtgctg ctgcaaacaa atcaaagcac ggacctggag tcgaaaattt 143161 tccttcctgg gcaaacattt gccaggcagg acatttcaga cataaagatt taaaacgttc 143221 cggtaattat atttcccggc attagtttcg ggttcaaaaa agcttttggt gaagtgctga 143281 taaccctgct tatcatatat cggttgtttg acaggggcat gacaactact ttctctccgc 143341 aataatccac ctcaatataa ttttgcttct ggttttcaca ccagtcaaag tttccaaata 143401 ctatttccgg cggtactatt gaataaagta tcattgcaat ccctccggct tttgtacagt 143461 cccctgggaa atgctatttt tgttcttttt tcttttagct atcaattcat acagtttctt 143521 gagcgcctcc ttaagtccgc ccatctcatc aataagcccg tattttacgg cttcctcacc 143581 aaacaatatg gttccaacgt cgtttgccag ctctcctgtc tttagcataa gttcccggaa 143641 gcgttccttg gatatattcg aattcttggt gacaaactgc accactctgt cctgcattct 143701 gtcaaaatat tcataagtct gcggcacacc tatgaccatt ccgttgagcc ttatgggatg 143761 tattgtcatt gtcgccgaag gtgcaatgaa agaatagttg gttgccaccg ccatcggcac 143821 accaatactg tgtcccccgc ccaatacaag ggaaaccgta ggctttgaca tgcttgcaat 143881 catttcggct atggcaaggc ctgcctccac atcccctccg acagtgttta aaataagcaa 143941 aagtccgtcg atttcttcac tctcttcaat tgccacaagc tgaggtatta catgctcata 144001 tttcgttgtt ttgttttggg gaggcagtac catgtgtccc tctatctgcc ctatgaccgt 144061 aagacagtgg atatttccct tggagcttga tatggacgtt ttacccaatt cttttatttc 144121 ttcgaactca ggcttttttt cattttcgct taccgtttca tcaaccgaag ctcttccaac 144181 cgtaatcttg ttttcctcta tcaaatcatc acttccttag tatgtatgaa ttaatctatt 144241 agtattattt ttaggatgaa aaatattata ctcaacaaaa aagttctgca tatattttca 144301 tgcagaactc tttatgagca gatatttgca aacagtcaac cgcaagcaga atttttacat 144361 aaggtcaata gtatcttctt tccttttttc ttctttcttt tcgtctttct tttcactttg 144421 ctttgtatct ttcttttggt agaattcatt gagtttgatt tcgtctatca taagcttgtt 144481 atccttattc ttcatactta cggtataatc atacttatag actaccttgt cacctatcat 144541 accatttgct tttaccacag aagcatcaaa gattacaaag tacatcttgt tcttttgggt 144601 gtaacccgga tgctggatta ttttaatatt atcaatactt tctattcttt ccatgttaac 144661 ctgcagcggg aaggacataa tattgaattt ctgagtgtaa tttgcatccg taaacaatat 144721 ttctttgtcg tttaccttgt ttattccaag gccgctcaaa aactccataa atcccgtata 144781 tccttcatac cattttgctc ttaaaagagc cattctttcc ctgtcaagtg ccaacaagtt 144841 tttgaagaac tgttccagca aagctttctc attatcaagc tgctgctttt cttcaggaat 144901 attttcatca agatactgtc ttttttcaat aaactcattg ttaagttttg aaattctttt 144961 tgaaagcggt gatttgaaat cagcttcctt ttgggtaagt actttgtagc cgtctccttc 145021 ttttacaacc tcaacatcgt atttggccgt tacctttata taatcatagt cttcttcggg 145081 aacaacttta tccacgccgt tttcctttat cttttcataa acattggttt cattatttaa 145141 tacataatac ttatggaaaa ggctgtttgg caaacctttg gctttaagcc ccactcttac 145201 ataataaaga taagcatcac cgtttttacc tataaagtct gattcaataa caggattgtt 145261 gtttgcatcc ttaagtattt cataattcaa catggtcatt ccgttgactt caacaaatct 145321 tggaaaatgg atacctacct caggattctt gtctccttct ttaatagtcc tttccgctat 145381 atagttttta atatttgccg gaatttcacc cgtcagaagg ttgtttttat agctctccac 145441 attctgtcca aacaaagcac caaagtattc cgtcatgaat tcctggactt ttttatcttc 145501 ctcagcgctg gtatccggtg tctcaatttt tggaggctca gtatcagtcg ccggtggctt 145561 gttaaacaac accgaacagc ctgtactgaa aacagttgcc gtaatcagag ttgaaactgc 145621 caatatcttt aactttttat tcataagctc caccccataa tttattaaaa tttagaatat 145681 attatataaa taaataccaa gttctgcaaa tttattaaga agattatttc tggctgccat 145741 attcaaataa tcatttctgc ctttttctat aatttcagac tcagttgtaa gtcccaaata 145801 aaagtcaacc ttcacgatac ccgggtcact gtttgaagcc ggaaccatct tgactcccgc 145861 gtaccttcca cggtcaagtg caaccgcctg gaaagtatct ctatccagtc tgttaagttt 145921 cagctcgtat tctcctgctg atctgtctcc gcctccgccg ctgattattg ctccccttat 145981 gtcggcacca ccatttaata tgactgaacc ggccgtaagt attataccgt tgaatgttcc 146041 gtcaacaatc aggtcgattt ccgggttctc gttaaatacc aaaaagtatt ctgtatcgct 146101 ttcaaaggta cctcctgttc tgctttcctg gcatctacca tacagatcaa aacccgccaa 146161 tgcagctaaa ttgtattgac ctttcgaaag acctggattt acttgaatat aatactcatt 146221 cgccgtatat gcactaaact ggctttttgc tttttgtata agctttacaa taccatgttc 146281 cccggaaata tcccattcac ttccgctggt tggatatttt ctgtttgcaa gaagctgagt 146341 ataatccaaa agattatttt ttacattgtc gggatctcca atctctcctg acatatccag 146401 tttggtgaaa actttgtgtg tataggaagg atcatcagcc tccggaacat cattccaaag 146461 attaaagtca aactttaaac cgattatatt tccatagctg tctttcttat aaatattgtc 146521 aattgcaaac cctggacgtt taacatagtc aattcctttc acacccacag cttcatagtc 146581 tcttccttca gtagacaaac gtccggcata ataacgccag tttgcagcca attcatacga 146641 ccatgctccc gatacagctc ccgggactga aacacctgcc tcagcagcat ttctcttgcc 146701 ccaaaccgct tttatactat ttataaagtc attagtaaca taatcatata atccgccacc 146761 cgtttcaata tcatcattta cacgttctct gctgggccaa agctgaaata aattaaacgg 146821 gccgttcaaa tacgcagcgg ataaatttct aagcctttcc ctcaactctg catggtattt 146881 atcaggattt aatatatcat cctcagtcca ctgatacatt ttgtaaaaag gtatccttat 146941 accgttggga tcttcgtacc agaacacaga cgcatcttcc agaagccctg taaaaatacc 147001 gtcatcatcc actctgaaag ttccacccgg aataatcaca tcaccgttca cggctatagt 147061 agacaataat gaatcatcag ataacaggtt atgtaccgga gcactgctta taatagcact 147121 caaagcatca tggttcctgc tctcaaaata atgggacaaa ccaatggcac ttccgtttat 147181 ggcaattatg gacctttcac cgttcatttc tatatcatca aaggtatatg catttctgaa 147241 aacggatatt atgttatcat ttccgaaaac ctgtatacat tgagctaccg catcacggta 147301 tatgtttatt ctgctttcgt ctgaaaagac ggcaggctca gaaagtcccc tgtaaacatc 147361 cctgtatggc cccgttctga taaacgccct tgaataagca tttcccttga tgtccacctg 147421 agcaccgtgc attgccatta ttccgccgta atagaactgc tcaggccaaa ggatatcttt 147481 agggaacgta ccaaaagcag atacgtcacc tttaatatcc accttgaatt caggcacggc 147541 cgctctaagg tctcctacat aattacgatt cctattctcc tcttcttcat taaaatgata 147601 acttcttgtg cttgcgtaca agtcagccgc agtagctatg gcaaaagtca gcttaaagtc 147661 attttgcgga acttcaaata caaattcctt ttcggcatat agtggttgcc gagtatttcc 147721 gtaaggactg ttgggattgt taaaagaagc ttccgcttcg ataccgatta cgacttttac 147781 cttttttcct ccttctatca attggggagt ccctatcact tccaaagcct tcagttttat 147841 ctccgaataa tcgtcacctg acaaacctgc aactgttggc gcttttgaaa caacatcgat 147901 atactctgta tcattcagct tcaatttcac tttatcaaga atcatctcaa catacctgtc 147961 aacattggta gcattcactt catcaggaaa accggcacca atattttgat cttccgattc 148021 tttttgtatt atattaaacc atttttcaat ggcagattga ccagcaaaat atgtaagttt 148081 gatattgctt tgacgtttgg acaaactcaa accttgaata gctgaattta aaaggactac 148141 ggacagggtc gtaagaactg ctgtaataat tattactgtt acaagcgcag ctccccgttc 148201 ttttttaagc agcctcaaca tatttcaaca cccccgttac aaaaaaataa cacatctata 148261 taaacataaa actatgttat ttacgattcc atacatatta aagtgtagta ttcacattag 148321 ccgcaatttt aaaggtattc agtgttttaa tctcgccttt gttatttttt gttaaaatat 148381 ttacaattac atggtaagta taaggatatt ccggatcata acaactctca tgcttataac 148441 taacggtata aaaatatttc tcattttttg cacctgaaga ataaaccaca gcaagattcg 148501 gtgatttctt ttcaacatca ggagttgact tggcatcagc aataaacggc ctcaaatacc 148561 actcagtccc tgtcggtgca gattcaagca acgtaagagg ataattttgc tgaatcaaag 148621 cctcagccac ctggtccttt actacctcgc tcacggcatt tacttctgtc tgccgttcaa 148681 taagtttggc tattcgaatc gtattcataa aaccaattgt tatcggaaca accaaaatac 148741 ccagcaaagc tagtgcaaca acaacctcta caagcgtcat gcctttgttg ttatttaatt 148801 ttctaaataa tctgaccata tcaatcacct tatacgttca aaaccatttt gttttccatc 148861 accgttaaac gatagtaacc ttctcaaccg agctgctttt atagatgctg tttccgttcc 148921 tatctgttat ttttgctctt ctgaccttgt catacaagtt aatatttatt tgtttgtcag 148981 tgttattgat aatctgcaca ttcacaccca aatctttatt ttcaatagga gttaaattat 149041 aattgagtac aatatgcatc tccacagtat cctttggcac atgcccggtc atatcgtaag 149101 tattgccggc attacccact acatttatgt cgactgtgtc accgttaaaa gtcattgtaa 149161 cctttggagt aatcttcgtt ctaaaattta tcgttttatt ggttgtattg tcatatgtat 149221 aaaaattttg tcctcccgta agaaaacttt gcatatatat acccaagtcc ccgccaaagg 149281 gttttgcatt gccggtcacc gctaccgtat ccgttccgct tcccgaagat ccgcctgatg 149341 ctccaccact tccacctgca cttatatttt cactgtcttc cccggagtta agtgctactc 149401 cggtatcatc aaaaaaaacc tggtctccct caaagtatct ctggaaattc tggcggctga 149461 agtcgtaaat tttatctgcg ttttcccggt tcatggaata catacaaact gtcataccca 149521 gatctaacac ttcatttggg tcaaaaatcg cttttgccaa agcattttgt gcattctgtt 149581 catctgattc cgtttgtggt tctgccgtat tctgaggagt cggtgttgca tttgcctgtt 149641 tattacccaa aggtgacact tcaaattttg ttatcttgac ttttcttgta ccgccttcaa 149701 gataatcgac aagctccata atttccctgt aagtcattgt tgcatcaaaa tcaatttgta 149761 tttcataata gctctgggca ttcttatcat ctttggagtt accaattttt ttctcagccg 149821 gtcttttgac ctttacgttg tacagtttgt ttttgaagag tttgccaagt ttttcaatat 149881 attcaaatcc atcacttaca ttggaatcat taagcaaata tgtctcaagt ctttcatttt 149941 gaactgtttt catctccaaa tttcttttca gcgtttctat atttgccaga tcattatcca 150001 gtttttgctt ctgtttttgc gcagtctcaa ttttggaatt aatgtcttct atatcaagac 150061 tgaattttgg tgtccaaata aactgataat atataactcc atataaaacc aacaataaaa 150121 caatcaaaag tgctatcttt cctttatcct tacccattag tttccatcct ttccgcctac 150181 acgcaatgta aagctgaata tatttccatt ctggacatta acttcactgt ccaaagttaa 150241 aaaactgagt ctctgaatag cagacacaaa ctcggcaatt acaaaattat ctttcgctat 150301 accggttaat ttcagtttat tattcttgaa ttcaatatta gttaatgtac atcccacagg 150361 ttcggcattt tttaatgcaa cgaatatatc atttatcgga taactggtac tgtcaatttg 150421 attcaaaaca gtttttttct ttgccaacac accgtcgata gatgccaaat ctgcatttac 150481 cttttttacc tcagcatatt tttcgctggt tatctctttt tcaagctggg caagttctct 150541 ttccagcatc tttatgtgta aaaccggtgc cagaattgaa catccgataa cgacacccac 150601 taaaattaag cctattacca actttatcac accggagcct gaacttggtc gctcatagga 150661 cgtcgtggac attatctctt ctggcagtaa attaatatca cccttcatta aagtattccc 150721 cctttgtatt tataattcaa tgaatgcttc aatatctgac aattgattta tatctaacag 150781 aatactctgt aattatctcc tcctgaacat ttcctgcttt atttacaatt ctatcgtttt 150841 gtttcggtag aatatgaaga atcaattgct ttacatcacc gttttcataa tattcaaaat 150901 aacttttact aatatcaata ttatcaacaa ctttaacaaa ttcgccagct acaccggaat 150961 taacaattct taattgaagc gaatcatcct caaacttcca ttcttttttg atttccggct 151021 ccccgggcaa attcatggtg aaaactaaac tactaagttt ttcctcaccc cttgcagcca 151081 catcaccggt catccacatt tcaacagttt tagcatcttg aacatcatgc cttacctgcc 151141 gtataacatc ctggatatca tactgctggt caataaaatt gcatccctgc gcaaaattat 151201 taagcccgcc aataagcaca gcataaatta ttggggccat tattcccatc agggctatca 151261 caactatcat ttccactaat gttacgccct tacagttatt cttaaacata atcactcacc 151321 ttgaaactat attctgtctc ttataaaccc tttcccggcc ggctcatgcc gaccgggaca 151381 agttacaact taaaatacta tatgtagcta ttaatctcat tcttcttctc cgttaaacac 151441 tcctacttca tcgccatttt cgttaccttc ctcaacaggt ttaacgtcag ctttctgaag 151501 acttggataa tatactatct tatatccaag atgattctta aactgaggag caaagttttc 151561 atatgcaggt gtatcgcctt ccttcggtgt caaatacggt ccataatatt tctcatcacc 151621 aacgggattt ccctcctcat ccacaggagt atatgcaatt ttctcttgca attgtctgat 151681 aataactttt ggatctgaat tgtcttcaaa tgcagtcaaa ttaacatctc ccgaatctgt 151741 catatacaat gacagagctt tcgcaatctg gtctgcagtt ctctcgtcag cccgcctctt 151801 agcattaccc aatacgccgg caaacatact gaatgctata gctgccaaaa cgcccatgat 151861 tgcgataact ataagcagct caaccaagga aaaacctttt tgattcttta acattttttt 151921 catacaaaac cctcctattt ttgttttatt ttatttattt tttatttatg ttgcttgtac 151981 ttgcctatat actttatctt attcccaaaa gaaatcgaat tagcagtatc cccccctaaa 152041 cttttttgga ataagataaa agtactataa gcaaagacta aatagacatt tcgttgtaaa 152101 tagtgaacat cggtgtcaac acactcaata ctataaaacc gacaaccaga gccaaaaaaa 152161 ttataatcgc aggctcaata aaacttgtca gcattgcaag ggaagcctca acttcctcat 152221 cataaaaatc tgccgatttg tcaagggcga aatccagatt acctgattct tctccgattc 152281 ggatcatcga aatgaccatc ggcggaaaat aattcaatgc tgcaagcggt gctgtaagac 152341 ctcttccttt ttttatttcc tcaataacac cgtcgatttt ctcccttata acctgatttc 152401 ccaatacttt ctggacaact tccatggcct gaatgagcaa cacaccgctg gacatcaatg 152461 ttcccaatgt tcttgtaagt ctcgccgtca ttatattcct cgtaactcct cttatcacag 152521 gaagcttgat agcgagtgtg ccaaaaaata tctttccttc ataggttcgt gaaaaatatg 152581 ctattcccgc accaataaca atcaaagcgc caagtataat aaaccaaaaa gatttaaaga 152641 aaccgcttac cgcaatcaat attcttgtat aaatgggcat ctcaacatca aaatccgcaa 152701 gaactttgac aaacgtcggc acaacagcca ccatcaatat cattataacg gctattgcca 152761 caaccgttac tataatcgga tatgtaagtg cacctcttat tttctggttc aatttgtttt 152821 ccttttcaaa ctgaattgcc attctcttaa aaaccagatc cagctgtccg cttatttctc 152881 cagcttcaac catgttaatc agcatctccg gaaaaattct cggatgctgc cgcatggcgt 152941 tggaaagggc aatacctttt tgtatgttgt cataaacatc atcaagacac tctctcaaag 153001 ttctgtttgt agtctgttcc ctcaacacat ccaatgcatt tgctataggt actccggctt 153061 ccaacactat ggaaaactgc ctgcagaata cagccaaatc ctttactttt actctcggct 153121 tgaacaaacg aatctgactt atatcgttta ttacattttt ctcaacaatt tctaccgggg 153181 tgtatccctt gtccagaagc agtcgccgaa gttcctcctc gctgtccacc ttggcctctc 153241 cggtaaacaa cttgccggcc tcatttttaa ccttgtagct gtaaagtggc attctttaaa 153301 cccccaaaaa agttattatc cgtaactttg aattcaattt ttattatgtt tttaaccatt 153361 tatttttgaa ttttttgtaa tatccgctga cacttttaaa aacttacaga actctcagaa 153421 cttcaaatct tactttattt tgaattaaat atcatgacca tacgttatta tgctttggcg 153481 agggataaga agatatcatg atgaacaatc cgaaaacgaa ttttacatcc aaatatgtac 153541 gaacagaagg ttctaatcca ttgatacaag aagcttattt tcaagctatg agtaagacat 153601 gtcaccaatc aatccaacct cccatattaa aacaaaccaa caaacaaaac aaataattta 153661 gtaaatattt attaacaatt tatatctatt tcttaatttt ttactcattt atattgtaat 153721 atatttttaa ataaaatgct agtgtttttt ttaatttgag attaattttc tcaaattatc 153781 catatcaaca gaatactggc atgcactttc atagtcaatt tcaccggctt tatagagttc 153841 tgcaaggcaa ctgtccatgg tatacattcc aaactgagaa cccgtctgaa tacaagtatt 153901 tatctgaggt gtacggcttt cacgaataag atttgaaata gcgggcgtcc aaaccatggt 153961 ctcagtagcc agcacacgtc ccttgccatt tgctcttttt ataagctgct gggatatgat 154021 acccataagc acggtggaaa gctgaaccct tacctgtgac tgctggtgag gcgggaaaac 154081 gtcgataatt ctgtcgatgg tctttgctgc tccgacggta tgcaaagtag acaaaaccaa 154141 gtgacctgtt tcagcagccg taagcgccgt tgcaatggtc tcctggtcac gcatctctcc 154201 gataagtata acgtcagggt cttctcttaa tacagctctc aacgcatttg cgtaggattt 154261 cgtatcagaa cctatttccc tctgatttat aatacttttg ttatgtctgt gcaaatactc 154321 tatagggtct tcaatcgtaa ctatgtgaca tcttctcttg ctgtttatgt aattaatcat 154381 ggcagccagt gtagtggact ttccatgacc tgtaggtccc gttaccaaaa caagacctct 154441 ctgcttcatg gcaaggtcat ataccaagcc gggaagcccc agctgctcaa ttgacggaac 154501 ttctgtaggt attgctctga atgcaattgc acaagtacct ctttgcttga aaacatttac 154561 cctgaatcgt gccactcccg gaaccgagta cgatgcatcg acttctccga cttcaagaaa 154621 gcgttcatac attctgctgc ttaaacattg cttggcaagc tgcacacaat catgcggagt 154681 taacaccggc tcgtttaaat ttataagatc gccgtagacc cttataatcg gaggcacccc 154741 cgcacaaata tgcaagtcgg acgcatcatt ttcgactgtc ttcctcagta aatcatttat 154801 atccatgtta catccccttt tctagtctat ggaatatgca atacgaagca tctcatctat 154861 cgtagtaata ccttctttaa ccaacctcgt acagttcatt ctcaatgttt tcatgcccat 154921 tttaatagcc gcatctttta ttacatcgga acttacgttc ttggatatca gttcctttat 154981 ttccctattg accgtcagaa tctcataaac cgctattctt cctttgtaac cggtattgtt 155041 acattcgtcg cacccttttg cacgatatat tgtaacttct tcatcatctt tcaagccaag 155101 aatctctctc tcattcttat ccggctggaa agcttccttg caatgaggac agagtcttct 155161 tacaagtctt tgcgcaatca atccaaccag agccgaagac aacaggaacg gctctattcc 155221 catgtcaatc attcttgtaa cagaacttgc agcatcgtta gtgtgcaatg tactgaaaac 155281 aaggtgtccc gtgatagctg cacggattgc tatttcagct gtttccgagt cacgtatctc 155341 tcccaccatt attatgtcgg ggtcctgtct taagaacgct ctcagtgccg tagcaaatgt 155401 caaaccagct tttacattca cctgtacctg atttataccc tttatagtac tttcaacagg 155461 atcctcaaca gtaagtatgt tgacattagg cttgcacaat tctctcagcg cggtataaag 155521 cgttgttgac ttaccgcttc cggtaggtcc ggtaaccagt ataataccgt aaggacttga 155581 tattatctgg tcaaatttct ccaaatcatc ttcaaagaat cccaactctt tcttcgaaac 155641 attaaagcct tccttgtcgg caattcttat aacaactttt tctccgaaca ttgtaggcag 155701 aacggaaaca cgcatgtcat actccctgtc gtcaattttt attcctattc ttccgtcctg 155761 aggaattctc ttttccgcaa tattcagacc gctgatgatt tttattctgg caacaattga 155821 agaaagaatc tttctgtcat atctcattat ctctaccagt tgtccgtcta ttctgaatct 155881 tattaaaaca caatcttcct ggggttctat gtgaatatca cttgctcttg tagccacggc 155941 tttctggaag ataatattaa ccatcttgac aatgggggca ttttcaagat cgctaatgtc 156001 aattgttgta tcttcatctt cagtttgagt tatttcaacc gcaatttttt catttacttt 156061 cttaatttcc tcgtcaagat ccgcaacctt ctgctctatt tctttcgcac tggtcttcct 156121 ggaagctttt ccgtagtatt tttccaactg tgccgaaatc tgctcttcat cggcaaggca 156181 aggaataatt tcaaggccgg ttgtaagcct caaatcgtca attgaaaata tgttcatcgg 156241 gtcgctcatc gcaaccttta aattcccgtc cactttttca atagggatta ccttgtgggt 156301 ttttgccaaa ttcggggata ccaaaccaat gatatcctca tcaatttcaa ttccctcaat 156361 atcaacgtat tcgactccca tctgtttttg gagaaattca taaagagacc ttctgtcaat 156421 atagccttgc tttactaaaa tctgaccgat aagtccgcca gattttttct gtatactgag 156481 ggcattttcc agttgatcct gtgtaataac tcccgcacgt acaaggatgt ttcctatttt 156541 atctttaaaa ataccgcttt cgttgtaagt attctgatca aatcccttgc ttgccaaatc 156601 aaattccggc tctctcgtct caacatcggc ttttatgtta ttatatatct ctcttccaag 156661 aagttcttcc tccattttta aaagttcttc tttcttgttc tgctcctcat tttccgcttt 156721 taatttcgat tcctgcggct tcttttcttc tccgaaatat tcaacaataa gtctttctat 156781 ctccttgaca tccgcaagga caggctttat ttccaaagca gttgcaagac gtatgtcatc 156841 tatacagaaa atatccgtcg gatcactcat tgcaactgtc aaaacaccat tttccttttc 156901 tatgggtata accttgtacc ggtttgctat gtttcgtgta attaataaag gaacactgga 156961 atcgctgatt tgataagttg acagatcgac gaaaggaata cccatcttca cggcattggc 157021 atgcattatg tctttctggg atacaagacc gagttccaat agcacgtcct caatgttctt 157081 attgctttcc ctctgaatat cccaggcttt tttaaggtca actattttta aaactcccat 157141 ttccaaaagt atttcatcaa tacctcttgt atctacccct agcatctcgt acccccacat 157201 cttatatgta attattttaa ttatgtaatt ttatttaata ctaatttaca aaccaattaa 157261 aatgaatcat gactgtataa atataaatga agattttata attattttat aattatagtt 157321 tatactaaat tctattcgtt gtgaagtata aattatgaat atgttggtta ttttacgata 157381 aaaaatgttt tgtaacggta tagctggaac taatatctgt actagtccta ttttaacatt 157441 ttttttaacg gttctcaagt acattttaag cttatttgct gatttgcctg caattccctg 157501 ctttcctgtt ttatcctctg aaaaactgca aagtcctcat tctgacatct gcaatatttt 157561 ttaaattctc cttaacatgt ttgtaatact caattgaata tgtgtcataa gcttttctta 157621 gcttacccac tccgacaaaa taaaaattat tgaacaaaac tccgtcaatc attaatttat 157681 ccgcacaatc aattattgtt ttaagagaa //