LOCUS NZ_ACVX01000005 120354 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00034, whole genome shotgun sequence. ACCESSION NZ_ACVX01000005 NZ_ACVX00000000 VERSION NZ_ACVX01000005.1 GI:256003677 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 120354) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 120354) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000005. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..120354 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene 135..806 /locus_tag="ClothDRAFT_0633" CDS 135..806 /locus_tag="ClothDRAFT_0633" /inference="protein motif:PFAM:PF02163" /note="PFAM: peptidase M50; KEGG: dps:DP0062 hypothetical protein" /codon_start=1 /transl_table=11 /product="peptidase M50" /protein_id="ZP_05428666.1" /db_xref="GI:256003678" /db_xref="InterPro:IPR008915" /translation="MLLQQFGDNPELIIYWFMVFAFSISVHESAHAYAAYLLGDPTAK EQGRITIDPLKHLDLFGTLMMLISFIGWAKPVPINPSNFKNKKAGTILVSLAGPLSNL ILAVLFAVPFAYVTLKYYPLENNPLNPAVIVYNFALYGFVMNISLAVFNFLPLPPLDG SKIFTAVLPSKYYFKIMQYHNVTFIILILLLYTGWLNKIITPVIGGVQSAILSVIVPI IKLIV" misc_feature 171..725 /locus_tag="ClothDRAFT_0633" /note="Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158" /db_xref="CDD:100079" misc_feature order(213..218,225..227,585..587,609..611) /locus_tag="ClothDRAFT_0633" /note="active site" /db_xref="CDD:100079" misc_feature 585..596 /locus_tag="ClothDRAFT_0633" /note="putative substrate binding region; other site" /db_xref="CDD:100079" gene 899..1888 /locus_tag="ClothDRAFT_0634" CDS 899..1888 /locus_tag="ClothDRAFT_0634" /EC_number="6.1.1.2" /inference="protein motif:TFAM:TIGR00233" /note="KEGG: dal:Dalk_5223 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib" /codon_start=1 /transl_table=11 /product="tryptophanyl-tRNA synthetase" /protein_id="ZP_05428667.1" /db_xref="GI:256003679" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002305" /db_xref="InterPro:IPR002306" /translation="MKKGTILSGMRPTGALHLGNYFGALENWVKLQDEYECYFFVADW HALTTGYEDTSQIKNNINDLVIDWLSAGLDPEKCVIFLQSSIKEHAELHLLFSMTTPL SWLLRCPTYKDQINQLKDKNITTYGFLGYPCLQAADILIYKAGFVPVGEDQLPHLELT REIARRFNYLFGEVFPEPQAILTKAKVLPGTDGRKMSKSYGNTIALSDSPDTIRKKVS SMITDPARIRKDDPGHPEVCTVFSFHKVFNENEVPEIEQHCRGGKIGCVQCKKNLADK MVEHLEPIYEKRQKIVENPSIVKEILADGNEKARKVAQKTLEEVRKAMKIDFI" misc_feature 902..1882 /locus_tag="ClothDRAFT_0634" /note="tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282" /db_xref="CDD:183400" misc_feature 911..1738 /locus_tag="ClothDRAFT_0634" /note="catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806" /db_xref="CDD:173903" misc_feature order(917..931,947..949,953..958,965..967,1016..1018, 1031..1033,1145..1147,1289..1291,1301..1303,1310..1312, 1337..1339,1343..1348,1352..1357,1364..1366,1457..1459, 1481..1486,1490..1492) /locus_tag="ClothDRAFT_0634" /note="active site" /db_xref="CDD:173903" misc_feature 947..958 /locus_tag="ClothDRAFT_0634" /note="HIGH motif; other site" /db_xref="CDD:173903" misc_feature order(1028..1030,1037..1042,1163..1168,1172..1180, 1187..1192,1196..1207,1211..1216,1277..1279,1283..1288, 1295..1300) /locus_tag="ClothDRAFT_0634" /note="dimer interface; other site" /db_xref="CDD:173903" misc_feature 1481..1495 /locus_tag="ClothDRAFT_0634" /note="KMSKS motif; other site" /db_xref="CDD:173903" gene 1927..2721 /locus_tag="ClothDRAFT_0635" CDS 1927..2721 /locus_tag="ClothDRAFT_0635" /inference="protein motif:PFAM:PF02616" /note="PFAM: chromosome segregation and condensation protein ScpA; KEGG: gme:Gmet_1959 condensin subunit ScpA" /codon_start=1 /transl_table=11 /product="chromosome segregation and condensation protein ScpA" /protein_id="ZP_05428668.1" /db_xref="GI:256003680" /db_xref="InterPro:IPR003768" /translation="MESVLSKACTIKIQNFEGPFDLLFHLIEKNQINIYDIPIHEITD QYMDYLFAMQELDLEIASEFLVMAATLLHIKSKLLLPSPKREKEEDEPDPREELVLKL IEYKKYKRFTEILKTREKECEKYFYRGPEDIDIKCEDEPLELSYDELKRVYVELIERN ERKMNKNTGKMTQIVQHEKVTLRSKIRDIIRTLLKKPIFKFSELFSPKTRSRLEIVTG FLAILELAKLKKITLIQPKPFADITVCKCEDTNLEDIDDENVAAEN" misc_feature 1957..2658 /locus_tag="ClothDRAFT_0635" /note="ScpA/B protein; Region: ScpA_ScpB; cl00598" /db_xref="CDD:186098" gene 2696..3337 /locus_tag="ClothDRAFT_0636" CDS 2696..3337 /locus_tag="ClothDRAFT_0636" /inference="protein motif:TFAM:TIGR00281" /note="TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: geo:Geob_3014 chromosome segregation and condensation protein, ScpB" /codon_start=1 /transl_table=11 /product="chromosome segregation and condensation protein, ScpB" /protein_id="ZP_05428669.1" /db_xref="GI:256003681" /db_xref="InterPro:IPR005234" /translation="MKMWQRKTDSSGVIQMDLKKLEGIFEGMLFASGDKVSIEKLSSI TGIDKKTVKLVINNMIVKYNNDPSRGITIREINNGYQLCSKPEYYDYIKQLFEPKQRS GLSQAALETLAIIAYNRPITKAKIEQIRGVNSDSAITKLLEKNLIREAGRLDAPGKPV LYETTDEFFRSFGFKSDADLPIFELNDIHETVEINQNSEQEKADTELEKQEKA" misc_feature 2762..3238 /locus_tag="ClothDRAFT_0636" /note="Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612" /db_xref="CDD:186106" gene 3368..3937 /locus_tag="ClothDRAFT_0637" CDS 3368..3937 /locus_tag="ClothDRAFT_0637" /inference="protein motif:PFAM:PF06271" /note="PFAM: RDD domain containing protein; KEGG: ccs:CCNA_00532 hypothetical protein" /codon_start=1 /transl_table=11 /product="RDD domain containing protein" /protein_id="ZP_05428670.1" /db_xref="GI:256003682" /db_xref="InterPro:IPR010432" /translation="MSEYDRKTDPQGFYNIFTVQPWVRFWARVIDTFIIDTIVRITQL LFFPGSTFEPVLLTVGTYFIWALAEAKLISTWGTTPGKWLLKIKVRSNNSQILDFKTA LKRSILVWMLGMGFGIFTTISYIFGYYELTRKGITPWDRISECTVQYEKISENRRIAV VLTVIGLSVMYFALIFVNALLYSIKAHGL" misc_feature 3428..3796 /locus_tag="ClothDRAFT_0637" /note="RDD family; Region: RDD; cl00746" /db_xref="CDD:153968" gene 4042..4254 /locus_tag="ClothDRAFT_0638" CDS 4042..4254 /locus_tag="ClothDRAFT_0638" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428671.1" /db_xref="GI:256003683" /translation="MFYRIIFVLIILILIIMVFFVKIKIVIEYRKGGQNDHFEVAFFV LKKRFGYKKTNQLKKRTEYLPIIKNL" gene 4304..4648 /locus_tag="ClothDRAFT_0639" CDS 4304..4648 /locus_tag="ClothDRAFT_0639" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428672.1" /db_xref="GI:256003684" /translation="MKILNYIKCRIYVERLEFKAVIGTGDASSAAILAGVAWSLAGIL FSILHSFTNVKNKKVEIRPDFTGKKFNVELYCIFKVKIVYIIVIGLMILKHLIKAKVG FTNVKRSIAVYK" misc_feature 4364..4516 /locus_tag="ClothDRAFT_0639" /note="Protein of unknown function (DUF2953); Region: DUF2953; pfam11167" /db_xref="CDD:151609" gene 4692..5180 /locus_tag="ClothDRAFT_0640" CDS 4692..5180 /locus_tag="ClothDRAFT_0640" /inference="protein motif:TFAM:TIGR02874" /note="TIGRFAM: sporulation protein YtfJ; KEGG: rfr:Rfer_0173 hypothetical protein" /codon_start=1 /transl_table=11 /product="sporulation protein YtfJ" /protein_id="ZP_05428673.1" /db_xref="GI:256003685" /db_xref="InterPro:IPR014229" /translation="MAEHPIQGLMETAMESIKEMVDVNTIVGDAVQAPDGTVIIPISK VTFGFAAGGGEFASCCSVDEKGEDSSDDSSKPEIKFPFAGGSGAGVSINPVAFMVVGQ GQIKLLPVNINSSLEKILDLIPEIIEKTKDSVKKNLKVKKEIKPGNGESCAKSSKEDE NE" misc_feature 4701..5075 /locus_tag="ClothDRAFT_0640" /note="Sporulation protein YtfJ (Spore_YtfJ); Region: Spore_YtfJ; cl01596" /db_xref="CDD:154494" gene 5378..6097 /locus_tag="ClothDRAFT_0641" CDS 5378..6097 /locus_tag="ClothDRAFT_0641" /inference="protein motif:PFAM:PF00849" /note="PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: gme:Gmet_1217 ribosomal large subunit pseudouridine synthase B" /codon_start=1 /transl_table=11 /product="pseudouridine synthase" /protein_id="ZP_05428674.1" /db_xref="GI:256003686" /db_xref="InterPro:IPR000748" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /translation="MKEMRLQKYLAECGVASRRKAEELISQGRVKVNGETVTQMGKKV SQNDVVEVDGKLVKMEKRKVYIALNKPVGYISSVKDQFGRKTVMDLVKDIKERIFPVG RLDYDTSGLLLLTNDGDFAYRLTHPKHEIKKVYEADLLGVPSKDDIMRFKNGLWIDDY FTSPADFEILKSDGKTTKVRITIHEGKNRQVRKMCNKIGCPVIRLKRISIGEVSLGDL KEGSWRNLTEREINSFLDNQK" misc_feature 5381..6076 /locus_tag="ClothDRAFT_0641" /note="16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187" /db_xref="CDD:31380" misc_feature 5387..5584 /locus_tag="ClothDRAFT_0641" /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165" /db_xref="CDD:29105" misc_feature order(5390..5392,5423..5428,5432..5437,5441..5446, 5453..5458,5462..5464,5483..5506,5510..5512) /locus_tag="ClothDRAFT_0641" /note="RNA binding surface; other site" /db_xref="CDD:29105" misc_feature 5570..6007 /locus_tag="ClothDRAFT_0641" /note="Pseudouridine synthases are responsible for the synthesis of pseudouridine from uracil in ribosomal RNA. The RsuA subfamily includes Pseudouridine Synthase similar to Ribosomal small subunit pseudouridine 516 synthase. Most of the proteins in this...; Region: PseudoU_synth_RsuA_like; cd02870" /db_xref="CDD:30030" misc_feature order(5681..5692,5951..5953) /locus_tag="ClothDRAFT_0641" /note="active site" /db_xref="CDD:30030" gene 6323..7150 /locus_tag="ClothDRAFT_0642" CDS 6323..7150 /locus_tag="ClothDRAFT_0642" /inference="protein motif:TFAM:TIGR00417" /note="TIGRFAM: spermidine synthase; PFAM: Spermine synthase; KEGG: GA20990 gene product from transcript GA20990-RA ; K00797 spermidine synthase" /codon_start=1 /transl_table=11 /product="spermidine synthase" /protein_id="ZP_05428675.1" /db_xref="GI:256003687" /db_xref="InterPro:IPR001045" /translation="MELWFTEYQTPTLGITCKTKKTLHSEKTEYQELAVIETEQFGRM LLLDGIIQTTVADEFVYHEMIAHVPLFTHKNPKKALVVGGGDGGSIREIVKHPSIEKA VLCEIDRRVIEVSKEYLPEISCALDNEKVEVVVGDGIKYVKEHKNEFDVIIIDSTDPI GPAEGLFAIDFYRAVYDCLKEDGIFVAQTESPFIDKELITRIIRDVKSLFPITRLYTC TIPTYPTGYWCFTMGSKKYDPLETDIDSIPDIDTKYYCPQIHRAAFILPKFAKELIK" misc_feature 6323..7147 /locus_tag="ClothDRAFT_0642" /note="spermidine synthase; Provisional; Region: PRK00811" /db_xref="CDD:179134" misc_feature 6554..6886 /locus_tag="ClothDRAFT_0642" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature order(6566..6586,6638..6643,6728..6736,6791..6793) /locus_tag="ClothDRAFT_0642" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" gene 7181..8050 /locus_tag="ClothDRAFT_0643" CDS 7181..8050 /locus_tag="ClothDRAFT_0643" /inference="protein motif:TFAM:TIGR01230" /note="TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: ilo:IL1212 agmatinase" /codon_start=1 /transl_table=11 /product="agmatinase" /protein_id="ZP_05428676.1" /db_xref="GI:256003688" /db_xref="InterPro:IPR005925" /db_xref="InterPro:IPR006035" /translation="MSLRNGNSTLPTKFMASIDSYDDASIVMAGVPMDFTCSFRPGTR FGPQKIREVSIGIEEYSVYMDRDLTQCSFFDAGDLDLPFGDVDKSLKLIGDVAEEILS DNKFPLFIGGEHLISVPVIKKVYEKYGPELIVVQFDAHADLREGYLGCPNSHASAVRR LIDFMPGKNIYQFGIRSGTKDEFEYAKKHTNMYTIDVFEPLSRVLDDIKDKPIYITLD IDVVDPAYANGTGTPEPGGISSRELLDSIHLFKGANLVGFDIVEVSPHYDQSDRTALL AAKIIREIIMMVG" misc_feature 7217..8041 /locus_tag="ClothDRAFT_0643" /note="Arginase family; Region: Arginase; cl00306" /db_xref="CDD:185892" gene 8059..8625 /locus_tag="ClothDRAFT_0644" CDS 8059..8625 /locus_tag="ClothDRAFT_0644" /inference="protein motif:PFAM:PF06962" /note="PFAM: putative rRNA methylase; KEGG: ppd:Ppro_0564 putative rRNA methylase" /codon_start=1 /transl_table=11 /product="putative rRNA methylase" /protein_id="ZP_05428677.1" /db_xref="GI:256003689" /db_xref="InterPro:IPR010719" /translation="MQTIKNSLGQSHDYIKMFVKEGDTVVDATCGNGNDTAFLASLVG ENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLIKDGHQNMDKYIDCPVKAVMFNLGY LPSGDHSISTRPETTIQALSKAMELLVTGGIITVVIYYGGDTGFEEKEKVLEFLKGVD QKKFIVQRTDFINQANCPPILVCIEKIS" misc_feature <8116..>8250 /locus_tag="ClothDRAFT_0644" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" misc_feature 8200..8616 /locus_tag="ClothDRAFT_0644" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene complement(8712..8804) /locus_tag="ClothDRAFT_0645" CDS complement(8712..8804) /locus_tag="ClothDRAFT_0645" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428678.1" /db_xref="GI:256003690" /translation="MFNRLKYSVYAISIFGIFLLIFIVFASKAI" gene complement(8789..9445) /locus_tag="ClothDRAFT_0646" CDS complement(8789..9445) /locus_tag="ClothDRAFT_0646" /inference="protein motif:PFAM:PF07238" /note="PFAM: type IV pilus assembly PilZ" /codon_start=1 /transl_table=11 /product="type IV pilus assembly PilZ" /protein_id="ZP_05428679.1" /db_xref="GI:256003691" /db_xref="InterPro:IPR009875" /translation="MLNDLLPQNDSPIFCRVSINNDEKWVHGIITYINMEKNIAEIFL SAKYFKSYFNEGSKIVVKSLDENIETLFSGSVSKKVISIRKQAITIQINKVLSYNNQR KYERFRVNYPCRIRYEENVSYIASISDISLGGGLIHSDDLFEEGKNIGIDMFVTPKIT ISFTGKVIRRIADKKGGYNYGVQLVDIDDANHNLLFELIEYLQTQKNTLPRSGKCLTG " misc_feature complement(8846..9148) /locus_tag="ClothDRAFT_0646" /note="PilZ domain; Region: PilZ; cl01260" /db_xref="CDD:163963" gene 9807..11357 /locus_tag="ClothDRAFT_0647" CDS 9807..11357 /locus_tag="ClothDRAFT_0647" /inference="protein motif:PFAM:PF01039" /note="PFAM: carboxyl transferase; KEGG: dol:Dole_0077 carboxyl transferase" /codon_start=1 /transl_table=11 /product="carboxyl transferase" /protein_id="ZP_05428680.1" /db_xref="GI:256003692" /db_xref="InterPro:IPR000022" /db_xref="InterPro:IPR011762" /db_xref="InterPro:IPR011763" /translation="MDKVDKIGLLREKLAQVEQGGGAEKIAKQHDAGKMTARERIQAL FDENSFVEIDTFVETRSIDFDMQKKKVPGDGVVTGYGSIDGRLVFVAAQDFTVIGGSL GEMHAAKITKVMDMAMKMGAPFISINDSGGARIEEGIDALKGFGDIFYRNTLASGVIP QISVIMGPCAGGAVYSPAITDFIFMVDKTSQMFITGPQVIKSVTGEDVTFEKLGGAET HNSISGVAHFRSSSEKECIEQIKKLISYLPDNNLSDVPIVPTQDDINRITDNLVDIIP QDSNKPYDMMEIITSVVDNGDFFEIQKDFAKNIIIGFGRMNGGTVGIVANQPKVAAGV LDVNSSDKAARFVRFCDAFNIPIITFTDVPGYLPGVGQEHSGVIRHGAKLLYAFSEAT VPKINVIVRKAYGGAYIAMNSKHLGADMVFAWPSAEIAVMGPEGAANIIFKKDIAAAD DPMETRKRLIEEYREKFSNPYVAASRGYVDDVIDPATTRIRLISALEMLASKRENRPA KKHGNIPL" misc_feature 9819..11354 /locus_tag="ClothDRAFT_0647" /note="methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117" /db_xref="CDD:130187" misc_feature 9906..10430 /locus_tag="ClothDRAFT_0647" /note="Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl00513" /db_xref="CDD:186049" misc_feature 10629..>11177 /locus_tag="ClothDRAFT_0647" /note="Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl00513" /db_xref="CDD:186049" gene 11385..11555 /locus_tag="ClothDRAFT_0648" CDS 11385..11555 /locus_tag="ClothDRAFT_0648" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428681.1" /db_xref="GI:256003693" /translation="MKEQINEEIILAISAAIAALETRPGYKLVVRSFKRIPQTSPVWS ATGKIERIRRSM" gene 11582..11980 /locus_tag="ClothDRAFT_0649" CDS 11582..11980 /locus_tag="ClothDRAFT_0649" /inference="protein motif:PFAM:PF00364" /note="PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: dal:Dalk_3782 conserved carboxylase region" /codon_start=1 /transl_table=11 /product="biotin/lipoyl attachment domain-containing protein" /protein_id="ZP_05428682.1" /db_xref="GI:256003694" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR001882" /translation="MKKFLIKVNGNQYEVEVEEIRDGASAPQVTLSTPSAAPAPSPAP AQETKAAAPKKDSTVPAGATAIKAPMPGTILDIRVNQGDTVKKGQVLLILEAMKMENE IVAPNDGTVASINVSKGASVNVGEVLVSLK" misc_feature 11582..11974 /locus_tag="ClothDRAFT_0649" /note="putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK05641" /db_xref="CDD:168146" misc_feature 11774..11974 /locus_tag="ClothDRAFT_0649" /note="The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase...; Region: biotinyl_domain; cd06850" /db_xref="CDD:133459" misc_feature order(11843..11845,11870..11878,11897..11899) /locus_tag="ClothDRAFT_0649" /note="carboxyltransferase (CT) interaction site; other site" /db_xref="CDD:133459" misc_feature 11873..11875 /locus_tag="ClothDRAFT_0649" /note="biotinylation site; other site" /db_xref="CDD:133459" gene 12124..13521 /locus_tag="ClothDRAFT_0650" CDS 12124..13521 /locus_tag="ClothDRAFT_0650" /inference="protein motif:PFAM:PF02436" /note="PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: hch:HCH_06704 pyruvate carboxylase subunit B" /codon_start=1 /transl_table=11 /product="Conserved carboxylase" /protein_id="ZP_05428683.1" /db_xref="GI:256003695" /db_xref="InterPro:IPR000891" /db_xref="InterPro:IPR003379" /translation="MAKVKITETALRDAHQSLIATRMRIEEMLPIIDKLDEIGYHSLE VWGGATFDACLRFLNEDPWERLRIIKSHCKKTPLQMLLRGQNLLGYKHYADDVVEYFV QKSVANGINIIRIFDALNDTRNIETAIKACKKEGGHAQGTVCYTISPVHNLELFVKDA KTLVEMGADSICVKDMAGLLLPYVAYDLIKALKENVKVPIQLHTHYTSGVASMTYLKA IEAGCDVVDCAISPMSMGTSQPPTEPLVATLKGTPYDTGLDLDKLSEIADYFRPLKEK YISEGLLDVKVMGVDVNTLKYQVPGGMLSNLVSQLKQSNAVDKFEEVLKEVPRVREDF GYPPLVTPTSQIVGTQAVLNVVTGERYKMVPKESKALIKGEYGRTPAPVNPEVQKKIL KDEEPITVRPADLIEPELDKIRNEMKEYLEQDEDVLSYALFPQVAEKFFQYRKAQKYK IEPDMVDYENRVHPV" misc_feature 12124..13467 /locus_tag="ClothDRAFT_0650" /note="oxaloacetate decarboxylase; Provisional; Region: PRK12331" /db_xref="CDD:183446" misc_feature 12139..12954 /locus_tag="ClothDRAFT_0650" /note="Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937" /db_xref="CDD:163675" misc_feature order(12157..12162,12169..12171,12253..12255,12265..12267, 12364..12366,12370..12372,12553..12555,12643..12645, 12730..12732,12736..12738,12838..12840) /locus_tag="ClothDRAFT_0650" /note="active site" /db_xref="CDD:163675" misc_feature order(12157..12162,12253..12255) /locus_tag="ClothDRAFT_0650" /note="catalytic residues; other site" /db_xref="CDD:163675" misc_feature order(12160..12162,12643..12645,12730..12732,12736..12738) /locus_tag="ClothDRAFT_0650" /note="metal-binding site" /db_xref="CDD:163675" misc_feature order(12664..12666,12670..12672,12745..12747,12751..12753, 12757..12759,12769..12774,12814..12819,12823..12825, 12853..12855,12871..12873,12913..12915) /locus_tag="ClothDRAFT_0650" /note="homodimer binding site; other site" /db_xref="CDD:163675" misc_feature 13006..13461 /locus_tag="ClothDRAFT_0650" /note="Conserved carboxylase domain; Region: PYC_OADA; pfam02436" /db_xref="CDD:145532" gene 13775..14302 /locus_tag="ClothDRAFT_0651" CDS 13775..14302 /locus_tag="ClothDRAFT_0651" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428684.1" /db_xref="GI:256003696" /db_xref="InterPro:IPR001282" /translation="MRKICCLLFAVFILCISASCYQRKETRISQPVIMPAIQSPEDID DYIGEKGYEILESKGKTEEYTLDKKRVYNNWQIWAVQYPEPDHYLGKEISIYSYIIRN HPLDDKSPNKKTYLSVMICENTIIGGYSSPYYEEKDISLVPIGGVYSLEGKNFEEIKN INFDRWRKRFIKKYE" sig_peptide 13775..13843 /locus_tag="ClothDRAFT_0651" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.943) with cleavage site probability 0.764 at residue 23" gene 14420..14662 /locus_tag="ClothDRAFT_0652" CDS 14420..14662 /locus_tag="ClothDRAFT_0652" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428685.1" /db_xref="GI:256003697" /translation="MDQKSFELLANMYHEIKEQLSEISKKLDKKADKSDIVRLENELT PKIQALFDGYKQHTDILERIENEVMKQDEIIMRRVK" gene complement(14723..15370) /locus_tag="ClothDRAFT_0653" CDS complement(14723..15370) /locus_tag="ClothDRAFT_0653" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428686.1" /db_xref="GI:256003698" /translation="MIQIDDAGSGSFVGGTCIGVYRPETNEYFFEIIPVELYNKENFK KKLYLDAVVDIVEEAFKALNVHKSETVEICRGYMFEKLRHWLDANGYCWYRTHISGRI QEIVEQNFMLYTMRLGVPEAYLKYTKYPFHFHKLLRWVFADYNNRISLCKTGWQSWAK YEGIQREVHDDVMKYSHIFCLKCGKHIRKGSRIKILRFVSNKEHFVYLHSKCHEC" gene 15550..15717 /locus_tag="ClothDRAFT_0654" CDS 15550..15717 /locus_tag="ClothDRAFT_0654" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428687.1" /db_xref="GI:256003699" /translation="MDLDDKLELKATVEVSANLELYKVVDFLNKNLKDKKLIFGLSKK DNKMIISIYET" gene 15742..16641 /locus_tag="ClothDRAFT_0655" CDS 15742..16641 /locus_tag="ClothDRAFT_0655" /inference="protein motif:PFAM:PF01380" /note="PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: bpy:Bphyt_3133 transcriptional regulator, RpiR family" /codon_start=1 /transl_table=11 /product="transcriptional regulator, RpiR family" /protein_id="ZP_05428688.1" /db_xref="GI:256003700" /db_xref="InterPro:IPR000281" /db_xref="InterPro:IPR001347" /translation="MDMDKEQDLLKRIQAGMPGFSKGQKLIANFIINHYDKAAYMTAA KLGEEVGVSESTVVRFANEIGFDGYPKLQKVLREMNKSKLTAVQRIEVTSSRINEGNI LKSVLQSDMEKIKATLEEIDQESFNNIVKSILNARKIYILGVRSSAPLASFLGFYFNL IFDNVRLVHTTSVSEMFEQIIHASRGDVVIGISFPRYSKRTINAMRFAQNQGATVVAI TDSLYSPLAKNADHVITARSDMASFVDSLVAPLSVINALIVAIGMSRKPHVQETFERL EKIWDEYKVYEKQDYDSNYGEED" misc_feature 15754..16596 /locus_tag="ClothDRAFT_0655" /note="Transcriptional regulators [Transcription]; Region: RpiR; COG1737" /db_xref="CDD:31923" misc_feature 16111..16521 /locus_tag="ClothDRAFT_0655" /note="RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose...; Region: SIS_RpiR; cd05013" /db_xref="CDD:88408" misc_feature order(16180..16182,16318..16320) /locus_tag="ClothDRAFT_0655" /note="putative active site; other site" /db_xref="CDD:88408" gene 16598..17275 /locus_tag="ClothDRAFT_0656" CDS 16598..17275 /locus_tag="ClothDRAFT_0656" /inference="protein motif:PFAM:PF00300" /note="PFAM: Phosphoglycerate mutase; KEGG: rpd:RPD_0651 phosphoglycerate mutase" /codon_start=1 /transl_table=11 /product="Phosphoglycerate mutase" /protein_id="ZP_05428689.1" /db_xref="GI:256003701" /db_xref="InterPro:IPR001345" /db_xref="InterPro:IPR013078" /translation="MKNKITIPITERKIKKVTVLYLVRHGQTDWNKENRCQGRIDTEL NSEGILQAEAIAQRLAGENIDVIYSSALKRAYTTAEIINRKLSRELVRNEALNEIDFG EWEGLTFEEMRKRPDYSYEQWRLMPHLVTFPGGEKSLKNVQDRAMKFVNEIIEKHNGN NILIVSHGGVIKLIILGMLGIGLEAYNKFFIANASLSIVVIESDRAFLRTLNDTCHIK NLITAKS" misc_feature 16655..17236 /locus_tag="ClothDRAFT_0656" /note="Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067" /db_xref="CDD:132718" misc_feature order(16667..16672,16817..16819,17096..17101) /locus_tag="ClothDRAFT_0656" /note="catalytic core; other site" /db_xref="CDD:132718" gene 17298..18527 /locus_tag="ClothDRAFT_0657" CDS 17298..18527 /locus_tag="ClothDRAFT_0657" /inference="protein motif:PFAM:PF03486" /note="PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: sat:SYN_00731 NAD(FAD)-utilizing dehydrogenases" /codon_start=1 /transl_table=11 /product="HI0933 family protein" /protein_id="ZP_05428690.1" /db_xref="GI:256003702" /db_xref="InterPro:IPR000759" /db_xref="InterPro:IPR001327" /db_xref="InterPro:IPR002218" /db_xref="InterPro:IPR003953" /db_xref="InterPro:IPR004792" /db_xref="InterPro:IPR006076" /db_xref="InterPro:IPR013027" /translation="MGKKVVVIGAGPGGIMAAGKAAERGHNVTLFEKNDRIGKKILIS GKGRCNITNNTDIEGLIENIPGNGNFLYSAFYTFSNHDLIEFFEQYGLKTKVERGGRV FPVSDDAKDVNNALLKFLNKAKVNLRLNSPVQEIKAKNNTVTGVVLKDGTEVPCDAVV LATGGASYPGTGSTGDGYVMAKKLGHTIVDLKPSLVPLLAEEEWVKELQGLSLKNVSI TILSKAGKKIYTDFGEMLFTHFGVSGPIILSASRHILDYDYKNVKLVIDLKPALSEEK LDERILRDFEKYSRKQYKNSLDDLLPKKMIPVIVKLSGIEPEKFVNQIKKEERRALVR LLKNLTLNINGSRPIKEAIVTAGGVSTDEINPSTMESKLVKGLYFAGEIIDVDGYTGG FNLTIAFSTGYLAGVSC" sig_peptide 17298..17351 /locus_tag="ClothDRAFT_0657" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.685) with cleavage site probability 0.341 at residue 18" misc_feature 17364..18515 /locus_tag="ClothDRAFT_0657" /note="Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; cl14644" /db_xref="CDD:187400" misc_feature 17364..18515 /locus_tag="ClothDRAFT_0657" /note="flavoprotein, HI0933 family; Region: TIGR00275" /db_xref="CDD:161797" gene 18633..19133 /locus_tag="ClothDRAFT_0658" CDS 18633..19133 /locus_tag="ClothDRAFT_0658" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428691.1" /db_xref="GI:256003703" /translation="MKVIVFRANTKKNKKTHAKAVNPRFGFERFLFFSFIILFSALVL VQAALMNPATRTFLVNDNGLEGSPLQFEEYLYSEGEISVALCSADVDENLKLLVNGEE VAVFSQNVINLKVKEGDVVSVDGSSTEEAEVAIVYATDNIKLDNIGERIKVNSEVKHI ARIIIE" sig_peptide 18633..18776 /locus_tag="ClothDRAFT_0658" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.781 at residue 48" gene 19373..19705 /locus_tag="ClothDRAFT_0659" CDS 19373..19705 /locus_tag="ClothDRAFT_0659" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428692.1" /db_xref="GI:256003704" /translation="MQSEYGKIGIRTAAVDYGGEFITSVMKIIERAVVSSKREGVITD NHVEEGAVAGATREALSQIMPKALGLNVGGKIGVARYKDHISVAVFFGIGLLHLNEVA IGLGHRVV" misc_feature 19376..19696 /locus_tag="ClothDRAFT_0659" /note="HutP; Region: HutP; cl07944" /db_xref="CDD:186718" gene 19788..20144 /locus_tag="ClothDRAFT_0660" CDS 19788..20144 /locus_tag="ClothDRAFT_0660" /inference="protein motif:TFAM:TIGR01796" /note="TIGRFAM: chorismate mutase; PFAM: Chorismate mutase of the AroH class; KEGG: ftw:FTW_1352 chorismate mutase" /codon_start=1 /transl_table=11 /product="chorismate mutase" /protein_id="ZP_05428693.1" /db_xref="GI:256003705" /db_xref="InterPro:IPR008243" /translation="MVWAIRGATTVSDNTADEIVAETQKLLKEMAEKNGLEEDDIISI IFTVTKDLDAAFPAIAARNMGWTSTALMCMNEIDVPGSLEKCIRVMMHVNTDKDKKDI KHVYLNGAKVLRPDLT" misc_feature 19791..20138 /locus_tag="ClothDRAFT_0660" /note="Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In...; Region: AroH; cd02185" /db_xref="CDD:100026" misc_feature order(19791..19799,19803..19805,19908..19916,19941..19946, 19953..19958,19971..19973,19995..20000,20004..20006, 20010..20027,20061..20063) /locus_tag="ClothDRAFT_0660" /note="homotrimer interaction site; other site" /db_xref="CDD:100026" misc_feature order(19803..19805,19953..19955,19962..19964,19971..19973, 20001..20006,20013..20018,20034..20036,20049..20054, 20103..20105,20124..20126) /locus_tag="ClothDRAFT_0660" /note="active site" /db_xref="CDD:100026" gene 20212..20895 /locus_tag="ClothDRAFT_0661" CDS 20212..20895 /locus_tag="ClothDRAFT_0661" /inference="protein motif:TFAM:TIGR00017" /note="TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: gme:Gmet_0865 cytidylate kinase" /codon_start=1 /transl_table=11 /product="cytidylate kinase" /protein_id="ZP_05428694.1" /db_xref="GI:256003706" /db_xref="InterPro:IPR003136" /db_xref="InterPro:IPR011994" /translation="MNGKARISIAIDGPAGAGKSTIAKIISKTLNILYLDTGAMYRAV ALKAIRESVDTLNREQMSKLVENIDIKIAHSEDIQRIFLDGEDVTDFIRTPEVSIGAS NVATVPAVRLKMVELQREIAKKNSVVMDGRDIGTYVLPDATLKFFLTASVEARAIRRY NELLSKGITQITLEDVKKDIEYRDKNDSNREFAPLSKAPDAIEIDTTDLTIEQVVNKI MEYAKDYVC" misc_feature 20227..20883 /locus_tag="ClothDRAFT_0661" /note="cytidylate kinase; Provisional; Region: cmk; PRK00023" /db_xref="CDD:178800" misc_feature 20236..20832 /locus_tag="ClothDRAFT_0661" /note="Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020" /db_xref="CDD:73296" misc_feature order(20542..20544,20605..20610,20779..20781) /locus_tag="ClothDRAFT_0661" /note="CMP-binding site; other site" /db_xref="CDD:73296" misc_feature order(20758..20760,20770..20772) /locus_tag="ClothDRAFT_0661" /note="The sites determining sugar specificity; other site" /db_xref="CDD:73296" gene 20885..21496 /locus_tag="ClothDRAFT_0662" CDS 20885..21496 /locus_tag="ClothDRAFT_0662" /inference="protein motif:TFAM:TIGR00530" /note="KEGG: gur:Gura_4298 phospholipid/glycerol acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase" /codon_start=1 /transl_table=11 /product="1-acyl-sn-glycerol-3-phosphate acyltransferase" /protein_id="ZP_05428695.1" /db_xref="GI:256003707" /db_xref="InterPro:IPR002123" /db_xref="InterPro:IPR004552" /translation="MYASLKNIYYGFLRAIITTFFDLFYRVSIIGIENVPVEGPVLLC ANHIAEMDMFFIGYRLKRLVRYMAKEELFRIPLVSSFIKSLGAFPVKRGKGDVGAIKT ALKLLEEGHIVGIFPEGTRLKNKKGKNIKAKPGAALLAQKSGAPILPVAISGRYRPFS KIKVVFGKPFTLDLDKNTKYTNSELVEFSESIMKKVYSLLGEY" misc_feature 20942..21445 /locus_tag="ClothDRAFT_0662" /note="Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989" /db_xref="CDD:153251" misc_feature order(21023..21025,21032..21034,21038..21040,21086..21097, 21239..21247) /locus_tag="ClothDRAFT_0662" /note="putative acyl-acceptor binding pocket; other site" /db_xref="CDD:153251" gene 21498..22124 /locus_tag="ClothDRAFT_0663" CDS 21498..22124 /locus_tag="ClothDRAFT_0663" /EC_number="1.17.1.2" /inference="protein motif:TFAM:TIGR00216" /note="KEGG: sat:SYN_02454 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein" /codon_start=1 /transl_table=11 /product="hydroxymethylbutenyl pyrophosphate reductase" /protein_id="ZP_05428696.1" /db_xref="GI:256003708" /db_xref="InterPro:IPR003451" /translation="MEIIVAKSAGFCFGVSNAVKTVNNLLENQKEPIYTYGPIIHNAQ VVDLFTSKGVKKIDDIDEAEPNGHIVIRAHGVTPDIYKKISDKGLILEDATCPYVKKI HNLVKEKSEEGYKIIIVGDRNHPEVIGINGWCNNQAYIVDSVDDVEKFPTSDEKVCVV AQTTITNEKWLEVNTALKKKFKNILKFDTICSATSRRQNEAEEIAKKC" misc_feature 21498..>22118 /locus_tag="ClothDRAFT_0663" /note="LytB protein; Region: LYTB; cl00507" /db_xref="CDD:186044" gene 22323..23582 /locus_tag="ClothDRAFT_0664" CDS 22323..23582 /locus_tag="ClothDRAFT_0664" /inference="protein motif:PFAM:PF00575" /note="PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: mxa:MXAN_3793 30S ribosomal protein S1" /codon_start=1 /transl_table=11 /product="RNA binding S1 domain protein" /protein_id="ZP_05428697.1" /db_xref="GI:256003709" /db_xref="InterPro:IPR000110" /db_xref="InterPro:IPR003029" /translation="MSELNKQGMVDILENDGEIDFANAFENSFVRIHAGDTVKGKIIG FNSNEVFVDLGYKADGIIPLEEYTDDPNFNIEKEVKIGEEVEVLVEMVNDGEGNVRLS KRKVDAIKSWDDIVKAYENKTPVNAYVVEVVKGGVIASYKGVRIFVPASQVSDRYVKD LNEFLKRSITVRILELNEKRRKVVGSARVIIEEEKEALANRTWNSMEVGKVFKGTVKS LTDFGAFVDIGGVDGLIHISELSWTRVKHPSEVLKVGDEVEVTVLEFDKEKKKVSLGY RKMEDNPWYKIEEKYKVGDVVKVTVLRFAPFGAFVELEKGVDGLVHISQISSKRLAKV EDALEIGMKVDAKIIEVDGENKKISLSIKEVMPIDPPSSKSESKAKDGSEAKETSANT EEEAEPTEHREDMNVTVEDLVSKTTQS" misc_feature 22425..22634 /locus_tag="ClothDRAFT_0664" /note="S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687" /db_xref="CDD:88442" misc_feature order(22449..22451,22473..22475,22503..22505,22509..22511) /locus_tag="ClothDRAFT_0664" /note="RNA binding site; other site" /db_xref="CDD:88442" misc_feature 22686..22886 /locus_tag="ClothDRAFT_0664" /note="S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465" /db_xref="CDD:88430" misc_feature order(22710..22712,22734..22736,22761..22763,22767..22769) /locus_tag="ClothDRAFT_0664" /note="RNA binding site; other site" /db_xref="CDD:88430" misc_feature 22944..23147 /locus_tag="ClothDRAFT_0664" /note="S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists of...; Region: S1_RPS1_repeat_ec3; cd05688" /db_xref="CDD:88443" misc_feature order(22971..22973,22995..22997,23022..23024,23028..23030) /locus_tag="ClothDRAFT_0664" /note="RNA binding site; other site" /db_xref="CDD:88443" misc_feature 23202..23411 /locus_tag="ClothDRAFT_0664" /note="S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain...; Region: S1_like; cl09927" /db_xref="CDD:186872" misc_feature order(23226..23228,23250..23252,23280..23282,23286..23288) /locus_tag="ClothDRAFT_0664" /note="RNA binding site; other site" /db_xref="CDD:88416" gene 23935..24309 /locus_tag="ClothDRAFT_0665" CDS 23935..24309 /locus_tag="ClothDRAFT_0665" /EC_number="4.1.1.50" /inference="protein motif:TFAM:TIGR03330" /note="KEGG: bba:Bd3616 spermidine synthase; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme; PFAM: S-adenosylmethionine decarboxylase related" /codon_start=1 /transl_table=11 /product="S-adenosylmethionine decarboxylase proenzyme" /protein_id="ZP_05428698.1" /db_xref="GI:256003710" /db_xref="InterPro:IPR003826" /db_xref="InterPro:IPR017716" /translation="MNALGRHILAEIYGCDAAILNNRNLIEKIMVESALEAGAEVREV AFHKFSPQGVSGVVVISESHLAIHTWPELGYAAVDVFTCGEKVNPWDACNYLTERFKA KHMTATEVKRGVFEEPVKVANL" misc_feature 23935..24303 /locus_tag="ClothDRAFT_0665" /note="S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687" /db_xref="CDD:186145" gene 24526..24936 /locus_tag="ClothDRAFT_0666" CDS 24526..24936 /locus_tag="ClothDRAFT_0666" /EC_number="2.7.4.6" /inference="protein motif:PRIAM:2.7.4.6" /note="KEGG: NME4; non-metastatic cells 4, protein expressed in ; K00940 nucleoside-diphosphate kinase; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase" /codon_start=1 /transl_table=11 /product="Nucleoside-diphosphate kinase" /protein_id="ZP_05428699.1" /db_xref="GI:256003711" /db_xref="InterPro:IPR001564" /translation="MERTLVILKPDSVKRKLVGEIISRFEKRNFTILHLKMMNIDREL ACEHYSHVKDKPFFNDMIDYITSGPVVVMVLSGYRVIEAVRSMVGATSNFDSKPGTIR GDYGYHRFENLIHASDSCESAEIEIKRFFPELDS" misc_feature 24529..24918 /locus_tag="ClothDRAFT_0666" /note="Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413" /db_xref="CDD:58528" misc_feature order(24550..24552,24670..24672,24694..24696,24778..24780, 24796..24798,24829..24831,24859..24861,24868..24870, 24874..24879,24901..24903) /locus_tag="ClothDRAFT_0666" /note="active site" /db_xref="CDD:58528" misc_feature order(24562..24564,24577..24585,24592..24594,24601..24603, 24628..24636) /locus_tag="ClothDRAFT_0666" /note="multimer interface; other site" /db_xref="CDD:58528" gene 25040..25822 /locus_tag="ClothDRAFT_0667" CDS 25040..25822 /locus_tag="ClothDRAFT_0667" /EC_number="2.1.1.80" /inference="protein motif:PRIAM:2.1.1.80" /note="KEGG: bra:BRADO1477 chemotaxis protein methyltransferase; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type" /codon_start=1 /transl_table=11 /product="MCP methyltransferase, CheR-type" /protein_id="ZP_05428700.1" /db_xref="GI:256003712" /db_xref="InterPro:IPR000780" /translation="MVMDYEGFKKEIFKLTGIDLGSYKEKQMKRRLDSLISKNNFSGY KTYIEALKTDKKLFNEFINYMTINVSEFYRNPEQWEKLKNIILPSLLEKNSNPKIWSA ACSSGDEPYTLVMILNEFLPLNKIKIIATDIDAEILVKAKNGLYTEKSIANLPKKYVE KYFKVDGDVYAINQEVKNCVEFSKHNLLADPYPKNCDLIVCRNVLIYFTEEAKAEIYK KFNRALKTGGVLFVGSTEQIILYNLYNFKPIQTFFYQKEKDI" misc_feature 25049..25804 /locus_tag="ClothDRAFT_0667" /note="Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138" /db_xref="CDD:128443" misc_feature 25049..25210 /locus_tag="ClothDRAFT_0667" /note="CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705" /db_xref="CDD:112515" misc_feature 25241..25753 /locus_tag="ClothDRAFT_0667" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene 25868..26023 /locus_tag="ClothDRAFT_0668" CDS 25868..26023 /locus_tag="ClothDRAFT_0668" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428701.1" /db_xref="GI:256003713" /translation="MFKRIAAWILLAGFVLLLLNITVFGIYREISAAIYLVVMIIYIF YLIANKK" sig_peptide 25868..25945 /locus_tag="ClothDRAFT_0668" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.689) with cleavage site probability 0.359 at residue 26" gene 26115..26402 /locus_tag="ClothDRAFT_0669" CDS 26115..26402 /locus_tag="ClothDRAFT_0669" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428702.1" /db_xref="GI:256003714" /translation="MVVAVQKGLDNLKRELAKRGFEVVDLETYNYPIDAIVYEGNSFQ ISYVSRNNMPQMTAGQRSNYGVFIVNALGKSINEIEDMLRTRYYSPLFELN" misc_feature 26121..26372 /locus_tag="ClothDRAFT_0669" /note="Uncharacterized protein family (UPF0180); Region: UPF0180; cl04214" /db_xref="CDD:186621" gene 26552..26983 /locus_tag="ClothDRAFT_0670" CDS 26552..26983 /locus_tag="ClothDRAFT_0670" /inference="protein motif:TFAM:TIGR00738" /note="TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: sat:SYN_03008 rrf2 family protein" /codon_start=1 /transl_table=11 /product="transcriptional regulator, BadM/Rrf2 family" /protein_id="ZP_05428703.1" /db_xref="GI:256003715" /db_xref="InterPro:IPR000944" /translation="MWLSTKGRYGLKAMLDLALHNGEGPVALKSIAERQNLPENYLEQ LFATLKKAGHITSVRGAQGGYLLSKDPDSITIGSILRSLEGSLAPVDCVVEDSSPKCD RFDNCVTKIVWEKIRDSVNEAVDSITLGDLVKESNKNSALS" misc_feature 26552..26962 /locus_tag="ClothDRAFT_0670" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" misc_feature 26552..26953 /locus_tag="ClothDRAFT_0670" /note="rrf2 family protein (putative transcriptional regulator); Region: rrf2_super; TIGR00738" /db_xref="CDD:129821" gene 27112..28296 /locus_tag="ClothDRAFT_0671" CDS 27112..28296 /locus_tag="ClothDRAFT_0671" /EC_number="2.8.1.7" /inference="protein motif:TFAM:TIGR03402" /note="KEGG: sat:SYN_01251 cysteine desulfurase / selenocysteine lyase; TIGRFAM: cysteine desulfurase NifS; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase" /codon_start=1 /transl_table=11 /product="cysteine desulfurase NifS" /protein_id="ZP_05428704.1" /db_xref="GI:256003716" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR001597" /db_xref="InterPro:IPR017772" /translation="MSDNRFVYLDHAATTPVKPEVLEAMLPYFSNKFGNASSIYSIGR ESKKAIEEAREKVAKAIGALPREVFFTGSGTEADNWAIKGVAYANRDKGRHIITTAIE HHAVLHACQYLESDGFEVTYLPVDENGLVSPQQVQDAIRPDTILITIMFANNEIGTIQ PIAEIGKIARERGVIFHTDAVQAVGNIPINVVDLNVDLLSMSGHKFYGPKGVGALYIR KGVKIVSFMHGGAQERGRRASTENVAGIVGMGKAIELAVENMEENNKKLIELRDRTIE EVMKKIPFVRLNGDRYKRLPGNVNFSFEFIEGESLLLMLDMKGIAASSGSACTSGSLD PSHVLLAIGLPHEIAHGSLRLTFGIENTHEDIDYLMEVLPTIVDRLREMSPLYEKVKR GN" misc_feature 27118..28230 /locus_tag="ClothDRAFT_0671" /note="Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520" /db_xref="CDD:30866" misc_feature 27130..28230 /locus_tag="ClothDRAFT_0671" /note="Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321" /db_xref="CDD:185903" misc_feature order(27331..27336,27343..27345,27562..27564,27646..27648, 27655..27657,27715..27717,27724..27726) /locus_tag="ClothDRAFT_0671" /note="pyridoxal 5'-phosphate binding pocket; other site" /db_xref="CDD:99742" misc_feature 27724..27726 /locus_tag="ClothDRAFT_0671" /note="catalytic residue; other site" /db_xref="CDD:99742" gene 28298..28747 /locus_tag="ClothDRAFT_0672" CDS 28298..28747 /locus_tag="ClothDRAFT_0672" /inference="protein motif:TFAM:TIGR03419" /note="TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein; KEGG: dol:Dole_0755 NifU domain-containing protein" /codon_start=1 /transl_table=11 /product="FeS cluster assembly scaffold protein NifU" /protein_id="ZP_05428705.1" /db_xref="GI:256003717" /db_xref="InterPro:IPR002871" /db_xref="InterPro:IPR017787" /translation="MMYSEKVMDHFMNPRNVGEIENADGVGEVGNAKCGDIMKMYLKI ENDVIVDAKFKTFGCGAAVATSSMATELVKGKTIEEALKITNKAVAEALDGLPPVKMH CSNLAEEAIRAAIDDYRRKNGLLPEGSENNACGRRCDDIHHGIDDED" misc_feature 28301..28639 /locus_tag="ClothDRAFT_0672" /note="Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664" /db_xref="CDD:143480" misc_feature order(28301..28312,28319..28324,28397..28402,28472..28474, 28478..28480,28592..28597,28601..28606) /locus_tag="ClothDRAFT_0672" /note="trimerization site; other site" /db_xref="CDD:143480" misc_feature order(28397..28399,28472..28474,28604..28606) /locus_tag="ClothDRAFT_0672" /note="active site" /db_xref="CDD:143480" gene 28766..29845 /locus_tag="ClothDRAFT_0673" CDS 28766..29845 /locus_tag="ClothDRAFT_0673" /inference="protein motif:TFAM:TIGR00420" /note="TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; ExsB family protein; KEGG: geo:Geob_1979 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase" /codon_start=1 /transl_table=11 /product="tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase" /protein_id="ZP_05428706.1" /db_xref="GI:256003718" /db_xref="InterPro:IPR004479" /db_xref="InterPro:IPR004506" /translation="MSKKKVMVGMSGGVDSSVAAAILLEQGYEVIGATMQIWPDTDEE TKLVEGGCCSLSAVDDARSVANKLGIPYYVLNFKDIFEKSVINYFKDEYLKGRTPNPC IACNRFVKFESMLNKALSMGIDYIATGHYAIITYDDNKKRYLLKKSVTQQKDQTYALY NVTQEQLKHILMPIGNFTKEQVRAKAKELGLYVASKPDSQEICFVNDNDYGKFIEENT DKEIKPGYFVDTKGNILGKHRGIIHYTVGQRKGLGIALGKPMYVVRIDAENNTVVLGD ENEVYSKELTAYDLNFISIDKLEEPMRVKAKIRYSAKEADAVIYPLEDGKVRVVFDTP QRAVTPGQSVVFYDGDIVVGGGIIQ" sig_peptide 28766..28828 /locus_tag="ClothDRAFT_0673" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.904) with cleavage site probability 0.461 at residue 21" misc_feature 28775..29806 /locus_tag="ClothDRAFT_0673" /note="tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054" /db_xref="CDD:145938" misc_feature 28778..29806 /locus_tag="ClothDRAFT_0673" /note="tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs...; Region: tRNA_Me_trans; cd01998" /db_xref="CDD:30185" misc_feature order(28790..28798,28802..28813,28865..28867,28871..28873) /locus_tag="ClothDRAFT_0673" /note="Ligand Binding Site; other site" /db_xref="CDD:30185" gene 30272..31498 /locus_tag="ClothDRAFT_0674" CDS 30272..31498 /locus_tag="ClothDRAFT_0674" /EC_number="6.1.1.1" /inference="protein motif:TFAM:TIGR00234" /note="KEGG: sfu:Sfum_2577 tyrosyl-tRNA synthetase; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; RNA-binding S4 domain protein" /codon_start=1 /transl_table=11 /product="tyrosyl-tRNA synthetase" /protein_id="ZP_05428707.1" /db_xref="GI:256003719" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002305" /db_xref="InterPro:IPR002307" /db_xref="InterPro:IPR002942" /translation="MSSVFETLKERGYIAQLTHEEKIKELLEKEKITFYIGFDPTADS LHVGHFLQMMVMAHMQKAGHRPIALIGGGTAMVGDPTGRTDMRKMMTREEIKHNADCF KKQLSKFIEFGEGKAIMVDNADWLLDLNYIEFLRDIGVHFSVNRMLTAECFKSRLERG LSFIEFNYMLMQSYDFLKLYKEYGCIMQLGGDDQWSNILGGIDLIRRKEGKEVYGMTF TLLTTSEGKKMGKTEKGALWLDANKTSPYEFYQYWRNIHDADVIKCLKLLTFVPMEEI EEYAKLKDQEINIAKKRLAFEVTKLIHGEEEALNAQKTAEALFEKGASTDNMPTTEVA SGELSNGINIIDLLLKTKLIPSKGEGRRLIEQGGISVNDVRVEGFDRLVTMDDFNNGE LIIKKGKKTYHRVKLV" misc_feature 30272..31492 /locus_tag="ClothDRAFT_0674" /note="tyrosyl-tRNA synthetase; Validated; Region: PRK05912" /db_xref="CDD:180311" misc_feature 30368..31174 /locus_tag="ClothDRAFT_0674" /note="catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805" /db_xref="CDD:173902" misc_feature order(30374..30376,30380..30388,30407..30409,30413..30418, 30773..30775,30785..30787,30794..30796,30833..30835, 30839..30844,30851..30853,30929..30934,30953..30964) /locus_tag="ClothDRAFT_0674" /note="active site" /db_xref="CDD:173902" misc_feature 30407..30418 /locus_tag="ClothDRAFT_0674" /note="HIGH motif; other site" /db_xref="CDD:173902" misc_feature order(30488..30490,30497..30502,30662..30667,30671..30679, 30686..30691,30695..30706,30710..30715,30761..30763, 30767..30772,30779..30784) /locus_tag="ClothDRAFT_0674" /note="dimer interface; other site" /db_xref="CDD:173902" misc_feature 30953..30967 /locus_tag="ClothDRAFT_0674" /note="KMSKS motif; other site" /db_xref="CDD:173902" misc_feature 31301..31489 /locus_tag="ClothDRAFT_0674" /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165" /db_xref="CDD:29105" misc_feature order(31334..31339,31343..31348,31352..31357,31364..31369, 31373..31375,31394..31417,31421..31423) /locus_tag="ClothDRAFT_0674" /note="RNA binding surface; other site" /db_xref="CDD:29105" gene complement(31697..32494) /locus_tag="ClothDRAFT_0675" CDS complement(31697..32494) /locus_tag="ClothDRAFT_0675" /inference="protein motif:TFAM:TIGR01856" /note="KEGG: nam:NAMH_1464 histidinol phosphatase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein" /codon_start=1 /transl_table=11 /product="histidinol phosphate phosphatase HisJ family" /protein_id="ZP_05428708.1" /db_xref="GI:256003720" /db_xref="InterPro:IPR003141" /db_xref="InterPro:IPR004013" /db_xref="InterPro:IPR010140" /translation="MYDCHVHSSFSGDSNMDPKIAINTAMKLGFEGISFTDHLDIDYP DYDDVFMIDFDKYSEAMDRLKRDYSGKIKVLKGIEVGIQPHVIEESNDIVKKYDFDIV IGSIHVVDKTDLHNGDFCRNKSKNEAYLRYLEAVLECINLFDNFDILGHIDLIRRYGC YDDKTLKLDDFKDRVDAILKALVEKGKGLEVNTSGFRYNLDSPMPDYEIIKRYRELKG EIICTSSDAHTPEYIGYKFDYVKELVKNAGFKYTAHFENRKPVFTPI" misc_feature complement(31769..32488) /locus_tag="ClothDRAFT_0675" /note="histidinol phosphate phosphatase HisJ family; Region: hisJ_fam; TIGR01856" /db_xref="CDD:162564" misc_feature complement(32132..>32221) /locus_tag="ClothDRAFT_0675" /note="MoaC family. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine derivative to the...; Region: MoaC; cl00242" /db_xref="CDD:185858" gene 32870..34366 /locus_tag="ClothDRAFT_0676" CDS 32870..34366 /locus_tag="ClothDRAFT_0676" /inference="protein motif:TFAM:TIGR00277" /note="KEGG: scl:sce2546 putative regulatory protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region" /codon_start=1 /transl_table=11 /product="response regulator receiver modulated metal dependent phosphohydrolase" /protein_id="ZP_05428709.1" /db_xref="GI:256003721" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /translation="MRKRIIEVSTDYKILIVDDEEGIINSMKVMLTRSGYFCMGISNP LEAIETLKKEHFDMLILDYIMSPIHGDEVVAKIREFNKDIYILLLTGHKDLAPPLETI KALDIQGYCEKGDKFDQLLLLIESGIKSISQMRTIRQFKDGLNRILQAVPKIYQLQPI GVILEEILQGLMPLVNSKDAFILVDDCNSGEGKIIFKGVGEYDIKAESLVTMLSPELM ENIGRARDSKKVLLLDHGIILPLTNEQNKSIGVIYIESSNLGDGIKLLEIYSTQAASS INNAFLHSLINMKKEELDRTYQELRKRYIDTIEALRLTVDAKDIYTRGHSDRVAYYAV KLGEAFGLPEDQLELLKVGGIFHDIGKIGTADDILFKTDKLSYDEYEEIKKHPLKGAY ILSAISMFKDVVPLVKYHHERIDGKGYPEGLKGDEIPFLARILTVADAFDAMMSDRKY RSKLSLEETKEQFRLYSGTQFDPQVVEKLFEILENYDLMLEELSKTFT" misc_feature 32912..33247 /locus_tag="ClothDRAFT_0676" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(32921..32926,33053..33055,33077..33079,33137..33139, 33197..33199,33206..33211) /locus_tag="ClothDRAFT_0676" /note="active site" /db_xref="CDD:29071" misc_feature 33053..33055 /locus_tag="ClothDRAFT_0676" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature order(33062..33067,33071..33079) /locus_tag="ClothDRAFT_0676" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature 33206..33214 /locus_tag="ClothDRAFT_0676" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature 33245..33757 /locus_tag="ClothDRAFT_0676" /note="Domain of unknown function (DUF3369); Region: DUF3369; pfam11849" /db_xref="CDD:152285" misc_feature 33842..34258 /locus_tag="ClothDRAFT_0676" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077" /db_xref="CDD:28958" misc_feature order(33842..33844,33938..33943,34184..34186) /locus_tag="ClothDRAFT_0676" /note="Zn2+ binding site; other site" /db_xref="CDD:28958" misc_feature 33941..33943 /locus_tag="ClothDRAFT_0676" /note="Mg2+ binding site; other site" /db_xref="CDD:28958" gene 34545..35981 /locus_tag="ClothDRAFT_0677" CDS 34545..35981 /locus_tag="ClothDRAFT_0677" /inference="protein motif:PFAM:PF02127" /note="PFAM: peptidase M18 aminopeptidase I; KEGG: dat:HRM2_30320 putative peptidase M18 family protein" /codon_start=1 /transl_table=11 /product="peptidase M18 aminopeptidase I" /protein_id="ZP_05428710.1" /db_xref="GI:256003722" /db_xref="InterPro:IPR001948" /translation="MSDNKTAGQKLWENLSYNCPNVWNKIGNDEIKNTFAFCEEYKSF LDKSKTEREFVRETKKLAESKGFVSIDDVIDSGKPLKPGMKVYRVFKNKIVALAVIGS QPPEKGFNLVGAHIDSPRIDLKPNPIYEANEMVFLKTHYYGGIKKYQWVTIPLSMHGV IIRKDGSSVEIVIGEDENDTVFTITDLLPHLAAEQMQKKMSEGITGENLNILFGSIPY NDEKVKEKVKLNILKLLNEKYNITEEDLLSAELELVPSFKAKDVGLDKSMVGAYGQDD RVCAYTALRAVLDLDNVDKTAVCVLTDKEEIGSMGNTGAQSSFLENFIADICALSSEK YTDIILRRCLSNSKMLSADVNAAIDPTYEGVYDKLNSSFIGKGIVLLKYTGARGKSGA SDAHAEFMGEVRKLFNERKIFWQTAELGKVDQGGGGTIAQFVANMGMDVIDCGVAVLS MHSPFEVTSKVDIYMAYKAYREFLKYIK" misc_feature 34575..35975 /locus_tag="ClothDRAFT_0677" /note="Peptidase dimerization domain; Region: M20_dimer; cl09126" /db_xref="CDD:186834" gene complement(36047..36973) /locus_tag="ClothDRAFT_0678" CDS complement(36047..36973) /locus_tag="ClothDRAFT_0678" /inference="protein motif:TFAM:TIGR00350" /note="TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="cell envelope-related transcriptional attenuator" /protein_id="ZP_05428711.1" /db_xref="GI:256003723" /db_xref="InterPro:IPR004474" /translation="MNFRRFYLIVCSILSVFMFFIGSLTLLYINFNTDVEKPVDNSGT LIDDILSPLKGVNEDLNVLVLGGDKVNNNTDTMMLVNFKPSTSKVSILSIPRDTKVKI NGKKAKINSAYPTGGGELAVQTVSELFGIDVKYYVFVDTSSFRKIIDILGGVDYYVPV DMDYDDPLQGLSIHIKKGQHHFDGAMAEKFMRFRQYNNGRVNEYYDGSDLKRIDAQQN FIRELVRQKLNIFYLTKVDDIASTIFSNIDTNLNMSEVLKLTGSVSKVQADSINMLKV PGKSVLDGAWYYVIDSQETDKIINEYFRTRYK" sig_peptide complement(36890..36973) /locus_tag="ClothDRAFT_0678" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.740) with cleavage site probability 0.273 at residue 28" misc_feature complement(36062..36940) /locus_tag="ClothDRAFT_0678" /note="Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581" /db_xref="CDD:186090" gene complement(37142..38134) /locus_tag="ClothDRAFT_0679" CDS complement(37142..38134) /locus_tag="ClothDRAFT_0679" /inference="protein motif:PFAM:PF00589" /note="PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: pla:Plav_1457 integrase family protein" /codon_start=1 /transl_table=11 /product="integrase family protein" /protein_id="ZP_05428712.1" /db_xref="GI:256003724" /db_xref="InterPro:IPR002104" /db_xref="InterPro:IPR004107" /translation="MNGAYYGEAPAIIKDFLSYMETIRGKSKNTIHEYYYDLRLFFRF MKIHFGLEDSKKDFDSIDIKDMDIDVIKKITLSDIYSFMSFLSRERDNTASSRARKVA SIRSFFNYLTNKAKLLEQNPAAELESPKIMKRLPRYLNIEESKRLLGSIDGEHKERDF AIITLFLNCGLRLSELVNINLSNIKNDVLTVVGKGNKERTIYLNAACKKALDAYLKVR PVDGVKDKNALFLSSRKQRISNKTVQHIVKKYIKAAGLDPERYSTHKLRHTAATLMYK HGNVDIRALQEILGHESIATTEIYTHVDSQQLKNAVESNPLSTYVDEHDNENES" misc_feature complement(37181..38113) /locus_tag="ClothDRAFT_0679" /note="site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236" /db_xref="CDD:178942" misc_feature complement(37208..38098) /locus_tag="ClothDRAFT_0679" /note="DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213" /db_xref="CDD:185831" misc_feature complement(order(37235..37237,37343..37351,37553..37555, 37616..37621)) /locus_tag="ClothDRAFT_0679" /note="DNA binding site" /db_xref="CDD:29495" misc_feature complement(order(37235..37237,37262..37264,37334..37336, 37343..37345,37553..37555,37619..37621)) /locus_tag="ClothDRAFT_0679" /note="Int/Topo IB signature motif; other site" /db_xref="CDD:29495" misc_feature complement(order(37235..37237,37262..37264,37334..37336, 37343..37345,37619..37621)) /locus_tag="ClothDRAFT_0679" /note="active site" /db_xref="CDD:29495" gene 38409..40022 /locus_tag="ClothDRAFT_0680" CDS 38409..40022 /locus_tag="ClothDRAFT_0680" /inference="protein motif:PFAM:PF00404" /note="PFAM: cellulosome protein dockerin type I; KEGG: dal:Dalk_4101 hypothetical protein" /codon_start=1 /transl_table=11 /product="cellulosome protein dockerin type I" /protein_id="ZP_05428713.1" /db_xref="GI:256003725" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MRMLKKCTGFFLYVLVLLVNIISVSALEPPPIYGDSNSDCKVNS TDLTLMKRYLLQQSISYINLINADLNGDGKINSSDYTLLKRYLLGYIDSFPVENQYPT TPEPSPTPTPAVDEEAWKNNTGTIELGDTIKVSGEGISVNGSVVTITAGGDHLVTGTL NNGMIFVNTTERVKLRLSGVNIKNPNGPAIYFYNVDKGFITIEKGTVNYLSDGSTYTD QDAKAALFSNDDLELKGKGTLYVTGNYKHGIASDDDLIIENGDIYVTAVTDGLHANSG IEIKGGNITVTAKSDAIESEKDFEMTGGTLNLTADDDAIHSEKDLVIDDGEINILKCY EGIESKTTITINGGKININSNEDGLNAASGLYINGGELYITSGYDGIDSNGPIYINGG YIFSFGGNIPEGGIDCDWNPLIINGGTLIAAGGSNSTPSTSSTQCSVLLGSGTANSVI SIQRNGSEIISFTAPKNYQNMVFSSPDLVLNATYVVYRNGVQSVTFTTNSIVTNAGGS SGGWFPGGGFPGGGFPGGGGGWFPGGPGW" sig_peptide 38409..38489 /locus_tag="ClothDRAFT_0680" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.965) with cleavage site probability 0.897 at residue 27" misc_feature 38610..38672 /locus_tag="ClothDRAFT_0680" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 40229..40912 /locus_tag="ClothDRAFT_0681" CDS 40229..40912 /locus_tag="ClothDRAFT_0681" /inference="similar to AA sequence:KEGG:Bd0818" /note="KEGG: bba:Bd0818 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428714.1" /db_xref="GI:256003726" /translation="MLDIALNANINSTLTLGSAFLTIIVSFALGILISVTYMKTHVKG YYSQNFTLTLILIPAVIAVIILLVGSNVARAFSLAGAFSIARFRSAAGDPKDIAYVLF SMAAGLACGTGLFGYAALFTVLLCVFMVVLCKINFGAKKSCEKILKILIPENMNYQGA FDDILKKYTTNYQLCRVKTTDLGTLFELVYTVTMDNEKDEKEFIDELRCRNGNLSIVL SMNAAPNDF" gene 41056..41568 /locus_tag="ClothDRAFT_0682" CDS 41056..41568 /locus_tag="ClothDRAFT_0682" /EC_number="2.7.1.71" /inference="protein motif:PRIAM:2.7.1.71" /note="PFAM: shikimate kinase; KEGG: dat:HRM2_04810 AroK" /codon_start=1 /transl_table=11 /product="Shikimate kinase" /protein_id="ZP_05428715.1" /db_xref="GI:256003727" /db_xref="InterPro:IPR000623" /translation="MQKRNIVLIGMPSSGKTTIGQPLAKTLNMGFIDTDRIIMEKEKR PLRDIVNHDGLEKFLEIQQSTLMSLNVDNHVISTGGSVVYNEAAMEHLKRNSIVVYLK LEFDEIKKRLSSGRRLARDSNKSFEDVYKERVPLYEKYADVTIDCSSKNVQSIVAEIK NVYESMIKGI" misc_feature 41056..41535 /locus_tag="ClothDRAFT_0682" /note="shikimate kinase; Reviewed; Region: aroK; PRK00131" /db_xref="CDD:178887" misc_feature 41068..41514 /locus_tag="ClothDRAFT_0682" /note="Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the...; Region: SK; cd00464" /db_xref="CDD:30188" misc_feature order(41092..41109,41386..41388,41401..41403,41509..41511) /locus_tag="ClothDRAFT_0682" /note="ADP binding site; other site" /db_xref="CDD:30188" misc_feature order(41104..41106,41152..41154,41158..41160) /locus_tag="ClothDRAFT_0682" /note="magnesium binding site; other site" /db_xref="CDD:30188" misc_feature order(41158..41160,41230..41232,41239..41241,41290..41298, 41452..41454) /locus_tag="ClothDRAFT_0682" /note="putative shikimate binding site; other site" /db_xref="CDD:30188" gene 41630..42814 /locus_tag="ClothDRAFT_0683" CDS 41630..42814 /locus_tag="ClothDRAFT_0683" /EC_number="4.2.3.5" /inference="protein motif:TFAM:TIGR00033" /note="KEGG: sat:SYN_01934 chorismate synthase; TIGRFAM: chorismate synthase; PFAM: chorismate synthase" /codon_start=1 /transl_table=11 /product="chorismate synthase" /protein_id="ZP_05428716.1" /db_xref="GI:256003728" /db_xref="InterPro:IPR000453" /translation="MVGNTFGRIFRVTTCGESYAGAFRKNLQIPKELFGGLIAIVDGV PPGIKLTADFVQEELDKRRPGKTPLDTPRKERDKVYIFSGVMEDDITTGAPVGMIIPN DVIEDEHINKHKSYKEVVRPGQAGYTFFKKYGQFADNIGAGRASGRETAARVAAGAVA KAVLDTMGIDVIAFVTEIHGIKAQENITYEMAKANYRKNEINCPDLEKAKEMIEELKR IKEEGDSVGGVVEIIARGVPAGLGEPVFDKLQATLAHALMSIGAIKGIEFGEGFGHTK LKGSESNDVPYYDEASGRVRFKTNRAGGILGGISNGEDIRIRVAVKPTPTISIPQKTV NMYTLENVEVEFNTRNDPSICPRIYPVCEAMVRIALLDALYIAKGYRAISSNIDPRWD RL" misc_feature 41657..42748 /locus_tag="ClothDRAFT_0683" /note="Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304" /db_xref="CDD:143612" misc_feature order(41660..41680,41741..41743,41747..41749,41753..41755, 41765..41770,41867..41872,41876..41881,41903..41908, 41912..41914,41918..41920,41924..41926,42014..42028, 42059..42064,42086..42088,42284..42286,42299..42316, 42347..42349,42353..42361,42371..42373,42377..42382, 42389..42397,42401..42406,42410..42412,42419..42433, 42440..42445,42449..42454,42464..42469,42533..42535, 42542..42550,42554..42562,42581..42583,42587..42598, 42605..42607,42722..42724) /locus_tag="ClothDRAFT_0683" /note="Tetramer interface; other site" /db_xref="CDD:143612" misc_feature order(41684..41686,41813..41815,41996..42001,42062..42073, 42080..42082,42410..42415,42590..42595,42599..42607, 42689..42691,42701..42703) /locus_tag="ClothDRAFT_0683" /note="active site" /db_xref="CDD:143612" misc_feature order(41996..42004,42059..42061,42065..42067,42407..42415, 42593..42595,42599..42607,42680..42682,42689..42691, 42698..42700) /locus_tag="ClothDRAFT_0683" /note="FMN-binding site; other site" /db_xref="CDD:143612" gene complement(42908..43564) /locus_tag="ClothDRAFT_0684" CDS complement(42908..43564) /locus_tag="ClothDRAFT_0684" /inference="protein motif:PFAM:PF07238" /note="PFAM: type IV pilus assembly PilZ" /codon_start=1 /transl_table=11 /product="type IV pilus assembly PilZ" /protein_id="ZP_05428717.1" /db_xref="GI:256003729" /db_xref="InterPro:IPR009875" /translation="MKLRVGEIVTLKHYSAKRSNRGIISNSFDNNVVIKPERDFLIYN FFDSDPVVIGFENDNVVNICESTVKHVDYNQNTFTLTINHIQSITNKRLTQRFPVSLC AYILSRNTRVFSYIRNISLDGLALCSRQEFKKGDILTINTKIENIELTFEAQVVWKSI SEIGFEYGLVYYMPEDEFSKTIERCLEFLKMDQELSISRLKYEFEPLRRISQRKSIMN " misc_feature complement(43001..43297) /locus_tag="ClothDRAFT_0684" /note="PilZ domain; Region: PilZ; cl01260" /db_xref="CDD:163963" gene complement(44210..45331) /locus_tag="ClothDRAFT_0685" CDS complement(44210..45331) /locus_tag="ClothDRAFT_0685" /inference="protein motif:PFAM:PF01551" /note="PFAM: Peptidase M23; KEGG: gme:Gmet_1854 peptidase M23B" /codon_start=1 /transl_table=11 /product="Peptidase M23" /protein_id="ZP_05428718.1" /db_xref="GI:256003730" /db_xref="InterPro:IPR016047" /translation="MKRLFIIVLIASLTAALIFPVMADNNSLKDKMSEIDDKLNDISK QKVEIDKEKKELEREKKELINAENEANLEYQNLVSELEALDSQIESYETSLKDTEERY AKTLKAFEERLVTMYRNSYVSYLNILADSENLINFFERLELISSIAKKDKEIVKKVQD IKKDLTYKKQLVQYIKGAKQLELIRKKNNIDSLVASRSGLENKIKEREEEIRRLEEQE DKLIQQSYEIANQIRRSTGSIKNYAGGTMVWPVPSSRKIDSRFGTRLHPIFKKYKMHT GVDIDAAYGASIVAANNGIVIFSGWEDGYGYTVIIDHGGGITTLYAHCSKLLVNKGDK VRKGQTIAQAGSTGTATGSHLHFEVRIDGNVTNPLDYIK" sig_peptide complement(45260..45331) /locus_tag="ClothDRAFT_0685" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 24" misc_feature complement(44213..45307) /locus_tag="ClothDRAFT_0685" /note="Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942" /db_xref="CDD:34550" misc_feature complement(44228..44515) /locus_tag="ClothDRAFT_0685" /note="Peptidase family M23; Region: Peptidase_M23; pfam01551" /db_xref="CDD:144954" gene complement(45453..46259) /locus_tag="ClothDRAFT_0686" CDS complement(45453..46259) /locus_tag="ClothDRAFT_0686" /inference="protein motif:PFAM:PF00963" /note="PFAM: cellulosome anchoring protein cohesin region; KEGG: C2 calcium-dependent membrane targeting domain-containing protein" /codon_start=1 /transl_table=11 /product="cellulosome anchoring protein cohesin region" /protein_id="ZP_05428719.1" /db_xref="GI:256003731" /db_xref="InterPro:IPR002102" /translation="MIKSSLIKTGIITVLAMLILCGCGGRTGKEPDAAEPTISGETNK PTASVEANRDALQSIDPVYTQSPENVNGTVVPNESPENNNMDNSNQTSNTANNDGTSS SAEANIQIVLDKNTAKKDEIITAKIILNNIPKIAGYQVNIKYDPNILQAVDLDTGKPL EDKQIPGGGDVLSNPDYNVLPLAASDVKNGVINFAKAYVNVDEYKESNNPESSGVLAL IGFKVLKEESTVISFADTPSMPNAVSGTYVYDWDFNVLTNYSVGKGVKVN" sig_peptide complement(46173..46259) /locus_tag="ClothDRAFT_0686" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.981 at residue 29" misc_feature complement(45465..45944) /locus_tag="ClothDRAFT_0686" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(45495..45497,45501..45503,45513..45515, 45663..45671,45681..45683,45738..45740,45744..45746, 45843..45848)) /locus_tag="ClothDRAFT_0686" /note="dockerin binding interface; other site" /db_xref="CDD:176099" gene complement(46439..50356) /locus_tag="ClothDRAFT_0687" CDS complement(46439..50356) /locus_tag="ClothDRAFT_0687" /inference="protein motif:PFAM:PF00963" /note="PFAM: cellulosome anchoring protein cohesin region; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="cellulosome anchoring protein cohesin region" /protein_id="ZP_05428720.1" /db_xref="GI:256003732" /db_xref="InterPro:IPR002102" /translation="MKKGISFILVIAIIMAMTSSFAVSAYPATTLSAAGVESGSISLE FDKTTAQVGDIIKAYVKISNIKNFAGYQVNIKYDPTVLQAVNPDTKVPLNKNTMPKSG NLLSNPEYGSIYGVLNKIEEGILNFGKAYTYLNDYKLSNSPEETGILAEIGFKVLKVQ PTTVKFENTSSMPGSLSGTMLFDWNGEVITDYTVVQSAVINSSVVNPSPSAAPSKGIV KMELNKNTAFVGDIIIAEIKVDNFDNIAGYQFNIKYDPQVLQPIDPDTNVPYGKSTMP KDGTILVNPEFGAISAVANKVEEGILNFGKSYTYLAAYKASGMAEKSGTIAKIAFKAL KAASSTTIKFEETLSMPGSIEGTMIFDWNGDNVLGYQVIQAGAVSISGQTVTPSPSPT QIPVSPTPIPSQKPTPSSTPVSNASISIEVDKNTVKVGEMVKAFVKVDGFDSLAGFQV NIKYNPDLLQAVNPDTGEPLKINSMPKSGDLISNNEYGVISIAVNKPSEGVLNFAKTY TYVGDYKDSGKPEKSGTLAIIGFKALNEGDATVRFEDAISMPSSLSGTILLDWDLNRI SDYKVVQPDVIKITGSTKPSPSPTSTPVGPSPTATPTGGPVSDGQIELKLDKEQAKVG DIIKAAINISDINNFAGYQVNIKYDPAVLQAVNPVTGEPMSDKSMPADGTILVNTEYG IISAVANKTSEGILNFGKAYTYLDAYKLSNNPEKTGTLAVIGFKVLKAQDTYIGFENS ITMPSSVLGTYLFDWNGDTITGYKVVNPGVIKISSSTVTTPSPTPTTTPTSTPKPTNP VSTDSYIKLELDKNTAAVGEIIKATVKVNNIKELAGYQINIKYDPNVLQPVNPYTGAE YTSKTPLANGELIVNSEYGATSMVVHDLTKGVLNFAQIYVFMEDYRNSGKAEETGVLG VIGFKVLKNEKTTIKFEEPASMPASISGTYLIDWNGNKKTDYKVIQPEPVNADAVSSG SYIKLEFDKNTASVGEIIRATVKVNNVKNLAGYQICIKYDPNVLQPVNPNTGAAYTTT THLVDGELIVKQEYGSTSMAAHRLSNGILNFARTYLYVSDYKEDGKPEETGILGVIGF KVLKKEKTTVSFYADEALMPNSVSGTYLIDWNSNKKTDYKVIQPEPINGGALPENYIA LELNKNKAAVGETIKATVRVNNIKNLAGYQVNIVYDPNVLQPIDPVTGAPFTTRSTFA NCELLNNDEYGPTNITAHDLTKGALNFARGYSYLNEYRKNGVPETTGVLGEITFKVLK SQTTKIRFEEPAAMPGSISGTYLFDWYGNQISNYSVIQPDSIN" sig_peptide complement(50279..50356) /locus_tag="ClothDRAFT_0687" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.804 at residue 26" misc_feature complement(49769..50242) /locus_tag="ClothDRAFT_0687" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(49793..49795,49799..49801,49811..49813, 49961..49969,49979..49981,50036..50038,50042..50044, 50141..50146)) /locus_tag="ClothDRAFT_0687" /note="dockerin binding interface; other site" /db_xref="CDD:176099" misc_feature complement(49232..49705) /locus_tag="ClothDRAFT_0687" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(49259..49261,49265..49267,49277..49279, 49430..49438,49448..49450,49481..49483,49487..49489, 49610..49615)) /locus_tag="ClothDRAFT_0687" /note="dockerin binding interface; other site" /db_xref="CDD:176099" misc_feature complement(<49052..>49240) /locus_tag="ClothDRAFT_0687" /note="putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK05641" /db_xref="CDD:168146" misc_feature complement(48632..49111) /locus_tag="ClothDRAFT_0687" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(48662..48664,48668..48670,48680..48682, 48830..48838,48848..48850,48875..48877,48881..48883, 49010..49015)) /locus_tag="ClothDRAFT_0687" /note="dockerin binding interface; other site" /db_xref="CDD:176099" misc_feature complement(48053..48529) /locus_tag="ClothDRAFT_0687" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(48080..48082,48086..48088,48098..48100, 48248..48256,48266..48268,48323..48325,48329..48331, 48428..48433)) /locus_tag="ClothDRAFT_0687" /note="dockerin binding interface; other site" /db_xref="CDD:176099" misc_feature complement(47471..47950) /locus_tag="ClothDRAFT_0687" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(47501..47503,47507..47509,47519..47521, 47669..47677,47687..47689,47744..47746,47750..47752, 47849..47854)) /locus_tag="ClothDRAFT_0687" /note="dockerin binding interface; other site" /db_xref="CDD:176099" misc_feature complement(46958..47440) /locus_tag="ClothDRAFT_0687" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(46988..46990,46994..46996,47006..47008, 47159..47167,47177..47179,47258..47260,47264..47266, 47339..47344)) /locus_tag="ClothDRAFT_0687" /note="dockerin binding interface; other site" /db_xref="CDD:176099" misc_feature complement(46451..46927) /locus_tag="ClothDRAFT_0687" /note="Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547" /db_xref="CDD:176099" misc_feature complement(order(46481..46483,46487..46489,46499..46501, 46649..46657,46667..46669,46694..46696,46700..46702, 46829..46834)) /locus_tag="ClothDRAFT_0687" /note="dockerin binding interface; other site" /db_xref="CDD:176099" gene complement(51158..51787) /locus_tag="ClothDRAFT_0688" CDS complement(51158..51787) /locus_tag="ClothDRAFT_0688" /inference="protein motif:PFAM:PF01648" /note="PFAM: 4'-phosphopantetheinyl transferase; KEGG: dat:HRM2_43120 Ffp" /codon_start=1 /transl_table=11 /product="4'-phosphopantetheinyl transferase" /protein_id="ZP_05428721.1" /db_xref="GI:256003733" /db_xref="InterPro:IPR004568" /db_xref="InterPro:IPR008278" /translation="MGFLPKEKKDKIKRFIKYEDALMSLTAEILIRAVVCSKLGIKNE SVKFNRTTYGKPYLEGYDDFHFNLSHSGSWVVCAVSSKPVGIDIEKIREVDLDIAKRF FSKEEASDLFAKEDNEKTEYFFELWTLKESYIKADGRGLSLPLNSFFFRIENDNVIFV SESEKKKFFFKRYDIDKGYKLAVCSMESHFPEDVEIKSFEEVCKFLCER" misc_feature complement(51182..51550) /locus_tag="ClothDRAFT_0688" /note="4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500" /db_xref="CDD:186039" gene 52066..52191 /locus_tag="ClothDRAFT_0689" CDS 52066..52191 /locus_tag="ClothDRAFT_0689" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428722.1" /db_xref="GI:256003734" /translation="MSEKGFFGGVFDDDTILWFIILFLLLFWCWSGYGYDYGAKG" gene complement(52446..52658) /locus_tag="ClothDRAFT_0690" CDS complement(52446..52658) /locus_tag="ClothDRAFT_0690" /inference="protein motif:TFAM:TIGR00003" /note="TIGRFAM: copper ion binding protein; PFAM: Heavy metal transport/detoxification protein; KEGG: atp7a; ATPase, Cu++ transporting, alpha polypeptide ; K01533 Cu2+-exporting ATPase" /codon_start=1 /transl_table=11 /product="copper ion binding protein" /protein_id="ZP_05428723.1" /db_xref="GI:256003735" /db_xref="InterPro:IPR000428" /db_xref="InterPro:IPR001802" /db_xref="InterPro:IPR006121" /db_xref="InterPro:IPR006122" /translation="MPKDILNLTVEGMSCNHCVNSIKKAVGGLEGVSNVDVDLKEKKV TVEYDSSKLEIETIKNAIEDQGYEVV" misc_feature complement(52452..52637) /locus_tag="ClothDRAFT_0690" /note="Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371" /db_xref="CDD:29471" misc_feature complement(order(52605..52607,52614..52622)) /locus_tag="ClothDRAFT_0690" /note="metal-binding site" /db_xref="CDD:29471" gene 52859..54583 /locus_tag="ClothDRAFT_0691" CDS 52859..54583 /locus_tag="ClothDRAFT_0691" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: xfn:XfasM23_1384 pyrrolo-quinoline quinone" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428724.1" /db_xref="GI:256003736" /translation="MNTKTSKIILTINIIILLLAVPGFIILDKYLERSNSNPDNIVAP PSPDVASNPGETTIPDVTASPENTDTKNWTAITPDEIDIVKECLPESHNFKWDVIKDG KKLDTYSRDNTVVFKPADEYNEIDGVTTFRGNNYRNSASFGSANVREEKLEKVWSIKI GYIDTWTGVGWNGQPAIVKWSNELRKKMNLFQDKKDKNDLKEVIYATLDGKIYFLDLD DGSYTRNPINVGAPLKGSVTVDPRGYPLLYSGQGIDEVKGQKVSIGFRIYSLLDQKLL YFINGLDNTAFRYWGAFDSSPLLHKETDTLFLCGENGLLYSIKLNTDYDPAQPAISIK PDIVKYRYVSPVNGRLGTENSIAAFKNFGYFADNSGTLQCVDLNTLSPVWIRNITDDT DSTMGIEDLGGNNVYIYIANEVDLQGENGYSYVRKINALTGSLVWEKKYKCSYNADTN GGTLASPVIGKNEISNLVIFSIAKSYKKNGGKLIAFDKNTGDEVWVIDSDFYSWSSPV DVYTEDGKAYIIHCDSAGYMNLIEGKSGKILDKIPLGGNIEGSPAVYDNMIVVGTRGQ QIYGIRIK" misc_feature <53453..54436 /locus_tag="ClothDRAFT_0691" /note="Dehydrogenases with pyrrolo-quinoline quinone (PQQ) as cofactor, like ethanol, methanol, and membrane bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller; Region: PQQ_DH; cl11493" /db_xref="CDD:159495" misc_feature order(53498..53500,53504..53506,53513..53521,53528..53530, 53657..53659,53663..53665,53672..53680,53852..53854, 53858..53860,53867..53875,53978..53980,53984..53986, 53993..54001,54008..54010,54137..54139,54143..54145, 54152..54160,54167..54169,54311..54313,54317..54319, 54326..54334,54341..54343) /locus_tag="ClothDRAFT_0691" /note="Trp docking motif; other site" /db_xref="CDD:73185" misc_feature order(53576..53578,53612..53623,53792..53794,53960..53962, 54206..54208) /locus_tag="ClothDRAFT_0691" /note="active site" /db_xref="CDD:73185" misc_feature order(54377..54382,54386..54400,54404..54424) /locus_tag="ClothDRAFT_0691" /note="'Velcro' closure; other site" /db_xref="CDD:73185" gene complement(54598..55335) /locus_tag="ClothDRAFT_0692" CDS complement(54598..55335) /locus_tag="ClothDRAFT_0692" /inference="protein motif:PFAM:PF00392" /note="PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; KEGG: sbo:SBO_3362 DNA-binding transcriptional regulator FrlR" /codon_start=1 /transl_table=11 /product="transcriptional regulator, GntR family" /protein_id="ZP_05428725.1" /db_xref="GI:256003737" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /translation="MINKYSNVPLYSQLKNIIIEKIESGEYPPDTKIPSEQDFCELYN ISRPTVRQAISELTNNGYLYKEKGKGTFVSKPKSSITTKRYTGFTDSILDNEITNERD IISIEKITNRDFKKLDEVFSIANNQVVDFAKISYKSKNGEDIISLNTSYIPMNLFPDI IEDVKSKKPSYDMLRGKYPLLPAKTKSTLEIIYTEQYEAQYLMVQPGQALFMVSNIIF SKSGQVVEFVISKYRADKCKLLFENTK" misc_feature complement(54607..55329) /locus_tag="ClothDRAFT_0692" /note="Transcriptional regulators [Transcription]; Region: PhnF; COG2188" /db_xref="CDD:32371" misc_feature complement(55114..55311) /locus_tag="ClothDRAFT_0692" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377" /db_xref="CDD:153418" misc_feature complement(order(55123..55134,55138..55143,55171..55173, 55180..55185,55189..55203,55225..55230,55234..55236, 55303..55305,55309..55311)) /locus_tag="ClothDRAFT_0692" /note="DNA binding site" /db_xref="CDD:153418" misc_feature complement(54628..>54903) /locus_tag="ClothDRAFT_0692" /note="UTRA domain; Region: UTRA; cl06649" /db_xref="CDD:176600" gene complement(55554..56981) /locus_tag="ClothDRAFT_0693" CDS complement(55554..56981) /locus_tag="ClothDRAFT_0693" /inference="protein motif:TFAM:TIGR00928" /note="TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ADL; adenylosuccinate lyase; K01756 adenylosuccinate lyase" /codon_start=1 /transl_table=11 /product="adenylosuccinate lyase" /protein_id="ZP_05428726.1" /db_xref="GI:256003738" /db_xref="InterPro:IPR000362" /db_xref="InterPro:IPR004769" /translation="MKNTYESPLNSRYASKEMQELFSPDMKFRTWRRLWIALAEAEKE LGLNITDEQIEELKKYKDDINYDVAEMKEKEFRHDVMAHIHAYGEQCPNARPIIHLGA TSCYVGDNTDIIIMTEALKLIKKKLLCVISKLSDFAMKYKDLPTLGYTHFQPAQLVTV GKRATLWIQDLLMDLEDLDYILSNMKLLGSKGTTGTQASFLNLFENDHEKVKKLDMLI AKKMGFDKVFPVSGQTYTRKLDSRILNLLSSIAQSAYKFGNDLRLLQSMKEIEEPFEK HQIGSSAMAYKRNPMRSERICALARYVIVNALNPAITASTQWFERTLDDSANKRICIP EAFLAVDAILNIYINVADGMVVYPKVIEKHVLEELPFMATENIMMEAVKKGGDRQELH ERIRVHSMEAAKQVKVEGKKNDLIERIAADEMFGLSIDELNSVLAPENYVGRAPQQVE EFINEYVKPVLEKNKVEDIEVELKV" misc_feature complement(55617..56957) /locus_tag="ClothDRAFT_0693" /note="Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015" /db_xref="CDD:30365" misc_feature complement(55650..56957) /locus_tag="ClothDRAFT_0693" /note="Adenylsuccinate lyase (ASL)_subgroup 2; Region: Adenylsuccinate_lyase_2; cd03302" /db_xref="CDD:176471" misc_feature complement(order(55650..55652,55656..55658,55815..55820, 55836..55838,55845..55847,55857..55859,55977..55979, 55992..55994,55998..56003,56013..56033,56043..56048, 56055..56060,56067..56072,56076..56081,56088..56090, 56100..56102,56115..56120,56184..56189,56193..56198, 56202..56204,56214..56216,56235..56237,56256..56258, 56268..56270,56289..56294,56298..56300,56385..56387, 56394..56405,56451..56456,56472..56477,56484..56486, 56493..56498,56514..56516,56520..56537,56679..56684, 56688..56693,56718..56720,56745..56747,56910..56915)) /locus_tag="ClothDRAFT_0693" /note="tetramer interface; other site" /db_xref="CDD:176471" misc_feature complement(order(56100..56102,56115..56117,56121..56123, 56283..56285,56529..56531,56685..56687,56748..56750)) /locus_tag="ClothDRAFT_0693" /note="active site" /db_xref="CDD:176471" gene complement(57201..57611) /locus_tag="ClothDRAFT_0694" CDS complement(57201..57611) /locus_tag="ClothDRAFT_0694" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428727.1" /db_xref="GI:256003739" /translation="MGLEAEIYKKVKFLNCNKMRTYNVYFYNPLMWGEFDFWRILIEY FVEEADSIRIDCWNEEENIINEILPFSSSVDKESSKRMTILSLPVNEKTVEQILYNAF DEKKRVKWFSLFLQRDGEAFFLRSIMVKNFQLLV" gene complement(57792..59246) /locus_tag="ClothDRAFT_0695" CDS complement(57792..59246) /locus_tag="ClothDRAFT_0695" /inference="protein motif:TFAM:TIGR00797" /note="TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: ppr:PBPRA1552 hypothetical protein" /codon_start=1 /transl_table=11 /product="MATE efflux family protein" /protein_id="ZP_05428728.1" /db_xref="GI:256003740" /db_xref="InterPro:IPR002528" /translation="MNKTLYIKSILPRLKRTFIGDKKFYKTVLALVIPIIIQNSITNF VNLLDNIMIGQVGTAQMSGVAIANQLMFVFYLAVFGGLAGAGIFAAQFFGAGDNEGLR YTLRYKLWASAVILAVALAVFLSGGDWLISLFLKGEGDPSEAAAILEYGRVYLRIMLW GLLPFILSQVYGSTLREIGDTMVPMVASVAAVLTNLCFNWVLIFGKLGFPEMGVAGAA IATVISRYVELVIIAVYTHMNTARFGFVAGVYRSMRVPRGLALTIFNKGMPLLANEVL WAVGVSALTQIFSTYNLNVVGALNIANTITNLFNVAFISMGSAVAVMVGQALGAGDMQ RAKEYSWKLIFFSVCTCIIIGAVLVAVAPVIPRIYNTTEDVRKLSAHFMIVSAFYMPF FAISHCAYFTIRSGGKTFITLVFDSAYTWGVIVPVAYLIAKYADFDIYTAYPVCYFPD VLKSVLGLYIIKKGRWAQNIVANGTESEGVRCFG" misc_feature complement(57831..59186) /locus_tag="ClothDRAFT_0695" /note="Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534" /db_xref="CDD:30880" misc_feature complement(58644..59147) /locus_tag="ClothDRAFT_0695" /note="MatE; Region: MatE; pfam01554" /db_xref="CDD:144956" misc_feature complement(57957..58442) /locus_tag="ClothDRAFT_0695" /note="MatE; Region: MatE; pfam01554" /db_xref="CDD:144956" gene complement(59405..62257) /locus_tag="ClothDRAFT_0696" CDS complement(59405..62257) /locus_tag="ClothDRAFT_0696" /inference="protein motif:PFAM:PF07833" /note="PFAM: copper amine oxidase domain protein; peptidase S41; SMART: peptidase S41; KEGG: dal:Dalk_3905 C-terminal processing peptidase" /codon_start=1 /transl_table=11 /product="copper amine oxidase domain protein" /protein_id="ZP_05428729.1" /db_xref="GI:256003741" /db_xref="InterPro:IPR005151" /db_xref="InterPro:IPR012854" /translation="MKKIKQMKVALFLFSFLSVIVFMSVSSLALPDVPKKSSNTSGNM ANNGRVLKYDGWVYYSFDESGLYRMKEDGSQKKKICDGMYDNLTAYDGYIYGYCRYTK TNNPEETGLFRLKPDGTERVKISDKSMLFVTIYDGWIYYTSFDDNFKPYKMKLDATDD QKLSDYSASYINVDNQWVYFQNDANGGRIYKVKHDGSQITEVSDHGNMYTYLNIDGEW IYFSGHYFLYKMKVDGTELTPLFEELINNVNSKDSWIYFSVFEEGIYRIKTDGTQLQK LRDVEDFVSGISLTDEWLYYEVYDVKDSSTRVYRMRLDGSSHQKFKITEDHVPDEVEN VKIRIDGKFGEYSNVPLNLYGRILLPFREILKNLGVPDDDKHIIWDGKNRTVTVKKDN ITILLTIGKNTALVNGKEYVLDVAPIIYNDRTYIPTRFIAESLNKKVLWDGEKQIVSI CEPAEFEKVKDILAKTNDAMVNSVERYSVDQKNSMKYNNDYLDYEIQMTAKLEIDSKK RLCNIVGERKILETGNITNFNSEETSNIYCWCENEKIYLKDENYDLWYESELTEDEWE NFKRRVLSNYSYINADDLICSGFTVDETDEHYILKGEHIFDELISGALYELDIVNEII SGTNTELLINKKTYYLEKINTTVTGKEKSSYGGNFSIAVSLENTNFNSEARVTAPEGF DPDKLINKKAVELVNFISQAYLYFNEIDNFEEKSKEFITKKDFNFDDVKQYIEAIKAD DDVFTVCVDENSLEYGYKEEQIETKDLGKDAVYIKIKSFTEDVGDKFIEEADKIENSE DKTLVIDLRDNGGGFIISANDILDYLLPRCLMNYYISRSGDMLPVYSNDDYKEFKQIL ILVNENTASSAELLALGLKKHLKNTTVIGRTTLGKGVGQLVYRDDDKKFSVYLVSFYW NVKEQNVMKSGITPDIVVNSDSDYLKEVEKLLKSKR" sig_peptide complement(62168..62257) /locus_tag="ClothDRAFT_0696" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.982 at residue 30" misc_feature complement(61520..>61831) /locus_tag="ClothDRAFT_0696" /note="tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800" /db_xref="CDD:163025" misc_feature complement(60908..61195) /locus_tag="ClothDRAFT_0696" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature complement(59441..60163) /locus_tag="ClothDRAFT_0696" /note="C-terminal processing peptidase-like; serine protease family S41; Region: Peptidase_S41_CPP_like; cd07561" /db_xref="CDD:143477" misc_feature complement(order(59585..59587,59663..59665)) /locus_tag="ClothDRAFT_0696" /note="Catalytic dyad; other site" /db_xref="CDD:143477" gene 62564..64756 /locus_tag="ClothDRAFT_0697" CDS 62564..64756 /locus_tag="ClothDRAFT_0697" /inference="protein motif:PFAM:PF00759" /note="PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; cellulosome protein dockerin type I; KEGG: hch:HCH_02464 cellulase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 9" /protein_id="ZP_05428730.1" /db_xref="GI:256003742" /db_xref="InterPro:IPR001701" /db_xref="InterPro:IPR001956" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MKKFLSLILVVSFLIMLLTPSTKISAATTFNYGEALQKAIMFYE FQRSGKLPSTIRNNWRADSCLDDGKDVGLDLTGGWFDAGDHVKFNLPMAYTAAMLAWA VYEEKDAFVKSGQLKYILDEIKWATDYFIKCHPEPDVYYYQVGDGDIDHMWWGPAEVV HLRTKRPSYKVDITSPGSTVSAETAAALAAASIVFKDTDPQYSNLCLKHAKELFNFAD KTRSDAGYTAATNFYTSHSGFYDELTWAATWIYLATGDTSYLDKAESYVEFWSTEPQT DIMSYKWGHCWDDVRYGAQLLLARITNKPIYKESMERHLDYWTVGVDNSRIKYTPKGL AWLNNWGSLRYATTTAFLAAVYADWEGCSPQKAKIYNDFAKAQVDYALGSTGRSFVVG FGENWPQHPHHRTAHGSWYDSMNVPDYHRHVLYGALVGGPGESDNYRDDISDYQCNEV ACDYNAGFVGALAKMYNRYDGRPVPEFKAIEVPEDEFMVEAYVSSSDKNYVEIKTRLN NRTAWPARVSEGLSFRYFIDLTEVIEAGYGPNDLIISGGQGSSGKVSGPHLWNKEKNI YYIEVDYTGDRLFPGGQDHYRRDSSLRIAVPGNSGCWNSENDPSFKGLSKTSEFKKAE YIPVYEYGVKVAGIEPEGTVVQPSPSPTPTPTPPHSDDVLYGDINNDKTVNSTDVTYL KRFLLKQINSLPNQKAADVNLDGNINSTDLVILKRYVLRGISKLPYAP" sig_peptide 62564..62644 /locus_tag="ClothDRAFT_0697" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.984 at residue 27" misc_feature 62582..63958 /locus_tag="ClothDRAFT_0697" /note="endoglucanase; Region: PLN02420" /db_xref="CDD:178040" misc_feature 62654..63952 /locus_tag="ClothDRAFT_0697" /note="Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959" /db_xref="CDD:186543" misc_feature 64022..64279 /locus_tag="ClothDRAFT_0697" /note="Cellulose binding domain; Region: CBM_3; pfam00942" /db_xref="CDD:109977" misc_feature 64661..64723 /locus_tag="ClothDRAFT_0697" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene complement(64911..65519) /locus_tag="ClothDRAFT_0698" CDS complement(64911..65519) /locus_tag="ClothDRAFT_0698" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428731.1" /db_xref="GI:256003743" /translation="MKDVTFSAGTAFAVELEEESVSLVLTAYHLFGESGGLDEQIPAS VLPDVFEKVVFTDAYNDSECGECEKILKIEDADTYPEVNKDIVAFYYGENLNANRLKL SSKLPKKGETVWLAAPTILSVEPRLHKAKVKSASNKMLVFEYEEKDIELTATSGAPIL NSKGEVVGLNAAGGEQNGKKIGVANPCTGMAKMIKKALSKED" gene complement(65888..66952) /locus_tag="ClothDRAFT_0699" CDS complement(65888..66952) /locus_tag="ClothDRAFT_0699" /inference="protein motif:PFAM:PF01547" /note="PFAM: extracellular solute-binding protein family 1; KEGG: hch:HCH_02206 spermidine/putrescine-binding periplasmic protein" /codon_start=1 /transl_table=11 /product="extracellular solute-binding protein family 1" /protein_id="ZP_05428732.1" /db_xref="GI:256003744" /db_xref="InterPro:IPR001188" /db_xref="InterPro:IPR006059" /translation="MKKIALLLAVLMFVFTGCAGNVKNDPSKPLAGTTIYVYNWGDYI AEDTIERFTKETGIKVIYETFDSNETMYAKYKSGAVNYDVLIPSDYMIEKLIAENELL PLNFDNIPNAKYIDESFRNLGYDPENKYSVPYFWGTLGILYNKKMVQEEVDSWDILWD SKYKGQIIMMDSVRDTFAVALKRLGYSLNSTDKAQVDEAVASLIEQAPLVQAYLMDQV KDKMIGEEAALAVIYSGEAVYTSEYNENLEYAVPKEGTNFFVDAMVIPKTCQNKEAAE AFINFMNDPQIAYNNTKYVGYSTPHTEARDMLDEEIKNNPAAYPPQEIIDKCEVFVDL GPEMTVYYNDKWNELKASLR" misc_feature complement(65900..66952) /locus_tag="ClothDRAFT_0699" /note="Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687" /db_xref="CDD:31031" sig_peptide complement(66893..66952) /locus_tag="ClothDRAFT_0699" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.697 at residue 20" misc_feature complement(65900..66859) /locus_tag="ClothDRAFT_0699" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398" /db_xref="CDD:187020" gene complement(66949..67743) /locus_tag="ClothDRAFT_0700" CDS complement(66949..67743) /locus_tag="ClothDRAFT_0700" /inference="protein motif:PFAM:PF00528" /note="PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pcr:Pcryo_0237 spermidine/putrescine ABC transporter membrane protein" /codon_start=1 /transl_table=11 /product="binding-protein-dependent transport systems inner membrane component" /protein_id="ZP_05428733.1" /db_xref="GI:256003745" /db_xref="InterPro:IPR000515" /translation="MVKRGIEKLYLGLIMLFLYAPILTLIVFSFNDSKSRAKWGGFTL KWYKNMLNDPMISKSIYYTLLIALLAAVISTVIGTLAAIGIHVMKKKTKTVVLNVTYL PVLNPDIVTGIAFMLFFVAIGLKLGFTSMLIAHITFNIPYVILNILPKLSSLNKYTYE AALDLGAHPMQAIWKVIIPEIMPNIITGFLLAFTLSLDDFIISYFTTGSGVTNLSITI YTMTRRGIKPEINAVSTVMFLSILILLLIINKRSEKNNKKLGGVNV" misc_feature complement(<67144..67743) /locus_tag="ClothDRAFT_0700" /note="putative 2-aminoethylphosphonate ABC transporter, permease protein; Region: PhnU2; TIGR03262" /db_xref="CDD:132306" misc_feature complement(67027..>67425) /locus_tag="ClothDRAFT_0700" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature complement(order(67033..67038,67042..67047,67054..67059, 67087..67092,67129..67134,67141..67152,67171..67173, 67180..67185,67225..67227,67276..67278,67285..67290, 67300..67302,67306..67311,67318..67320,67324..67326, 67330..67335,67396..67398,67402..67407,67414..67425)) /locus_tag="ClothDRAFT_0700" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature complement(order(67135..67152,67396..67425)) /locus_tag="ClothDRAFT_0700" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature complement(order(67057..67059,67087..67089,67096..67098, 67132..67134,67348..67350,67396..67398)) /locus_tag="ClothDRAFT_0700" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature complement(order(67204..67206,67216..67221,67237..67275)) /locus_tag="ClothDRAFT_0700" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" gene complement(67737..68564) /locus_tag="ClothDRAFT_0701" CDS complement(67737..68564) /locus_tag="ClothDRAFT_0701" /inference="protein motif:PFAM:PF00528" /note="PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce9305 spermidine/putrescine ABC transporter, permease protein" /codon_start=1 /transl_table=11 /product="binding-protein-dependent transport systems inner membrane component" /protein_id="ZP_05428734.1" /db_xref="GI:256003746" /db_xref="InterPro:IPR000515" /translation="MNRKWLAAPYLVWMVIFIVVPLVMIFYYAFTAKDAGGLRFTFEH LIKAFDSKYLIALWKSLLYAFIATVICLVLAYPLALILAKHSKGGSVTLFIFILPMWM NFLLRTYAWLSLLETNNGLLNTFLRALHLPVLDIIGTPSAIVLGMVYNFLPFMVLPIY NSLAKIDKSVMEAAYDLGANDFQRLLRVTIPLSMPGVMSGITMVFMPAVTSFVIPNLL GNGKVNLIGNIIEQQFLLTYDWGFGAALSLVLMIMILISMAVMQRSDEDMEGGAGLW" misc_feature complement(67875..68396) /locus_tag="ClothDRAFT_0701" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature complement(order(67875..67877,67914..67919,67926..67937, 67956..67958,67965..67970,68010..68012,68061..68063, 68070..68075,68085..68087,68091..68096,68103..68105, 68109..68111,68115..68120,68229..68231,68235..68240, 68247..68276,68280..68291,68316..68318,68331..68336, 68343..68348)) /locus_tag="ClothDRAFT_0701" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature complement(order(67920..67937,68229..68273)) /locus_tag="ClothDRAFT_0701" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature complement(order(67881..67883,67917..67919,68133..68135, 68229..68231)) /locus_tag="ClothDRAFT_0701" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature complement(order(67989..67991,68001..68006,68022..68060)) /locus_tag="ClothDRAFT_0701" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" gene complement(68561..69619) /locus_tag="ClothDRAFT_0702" CDS complement(68561..69619) /locus_tag="ClothDRAFT_0702" /inference="protein motif:TFAM:TIGR01187" /note="KEGG: dvl:Dvul_2864 putrescine/spermidine ABC transporter ATPase protein; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="spermidine/putrescine ABC transporter ATPase subunit" /protein_id="ZP_05428735.1" /db_xref="GI:256003747" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005893" /db_xref="InterPro:IPR013611" /db_xref="InterPro:IPR017871" /translation="MERNVVIRLENVTKSFDDQVVLKNLTLDVRKNEFLTLLGPSGCG KTTTLRLIGGFEKPDEGIILHHGNDISNLPPYKRNVNTVFQKYALFPHLNVYENIAFG LKIKKMNKSLIKEKVEKALRQVNLVGYENRRIDQLSGGQQQRVAIARAIVNEPEILLL DEPLGALDLKLRQEMQYELKTLQKELGITFVYVTHDQEEALTMSDTVVVMNNGVIQQK GTPEDIYNEPVNAFVADFIGESNIVEGIMRQDGVVEIFGRVYECVDKGFAVNEKVDVV IRPEDIKLLEPSENKINGQVTSCIFKGVHYETCVMTDGFEWVIHNTKSFTPGENVSIN VDPFDIHIMKKMEKEAGT" misc_feature complement(68585..69616) /locus_tag="ClothDRAFT_0702" /note="ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842" /db_xref="CDD:33633" misc_feature complement(68906..69601) /locus_tag="ClothDRAFT_0702" /note="PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues...; Region: ABC_PotA_N; cd03300" /db_xref="CDD:73059" misc_feature complement(69482..69505) /locus_tag="ClothDRAFT_0702" /note="Walker A/P-loop; other site" /db_xref="CDD:73059" misc_feature complement(order(69035..69037,69134..69139,69365..69367, 69479..69487,69491..69496)) /locus_tag="ClothDRAFT_0702" /note="ATP binding site; other site" /db_xref="CDD:73059" misc_feature complement(69365..69376) /locus_tag="ClothDRAFT_0702" /note="Q-loop/lid; other site" /db_xref="CDD:73059" misc_feature complement(69182..69211) /locus_tag="ClothDRAFT_0702" /note="ABC transporter signature motif; other site" /db_xref="CDD:73059" misc_feature complement(69134..69151) /locus_tag="ClothDRAFT_0702" /note="Walker B; other site" /db_xref="CDD:73059" misc_feature complement(69116..69127) /locus_tag="ClothDRAFT_0702" /note="D-loop; other site" /db_xref="CDD:73059" misc_feature complement(69029..69049) /locus_tag="ClothDRAFT_0702" /note="H-loop/switch region; other site" /db_xref="CDD:73059" misc_feature complement(68591..68797) /locus_tag="ClothDRAFT_0702" /note="TOBE domain; Region: TOBE_2; cl01440" /db_xref="CDD:163979" gene complement(69629..70168) /locus_tag="ClothDRAFT_0703" CDS complement(69629..70168) /locus_tag="ClothDRAFT_0703" /inference="protein motif:PFAM:PF07883" /note="PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: gur:Gura_0980 XRE family transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, XRE family" /protein_id="ZP_05428736.1" /db_xref="GI:256003748" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR013096" /translation="MQIGAKIRQLRIANQMTQEELADRAELSKGFISQIENDLTSPSI NTLVDILQCLGTDLKTFFSDSEDKQIVFREKDYFSKTDNELKNTIEWVVPNSQKNAME PIRMTLQPGGRSLEDHPHEGEEFGYVVKGSIEVHIGNECYRVNEGESFYFESTRKHYI VNVGESDAQVIWVSTPPTF" misc_feature complement(69632..70159) /locus_tag="ClothDRAFT_0703" /note="DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943" /db_xref="CDD:182158" misc_feature complement(69986..70159) /locus_tag="ClothDRAFT_0703" /note="Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093" /db_xref="CDD:28977" misc_feature complement(order(70058..70060,70133..70135,70145..70147)) /locus_tag="ClothDRAFT_0703" /note="non-specific DNA binding site; other site" /db_xref="CDD:28977" misc_feature complement(order(70061..70063,70136..70138)) /locus_tag="ClothDRAFT_0703" /note="salt bridge; other site" /db_xref="CDD:28977" misc_feature complement(order(70055..70060,70070..70072,70079..70081, 70112..70117)) /locus_tag="ClothDRAFT_0703" /note="sequence-specific DNA binding site; other site" /db_xref="CDD:28977" misc_feature complement(69650..69856) /locus_tag="ClothDRAFT_0703" /note="Cupin domain; Region: Cupin_2; cl09118" /db_xref="CDD:186830" gene complement(70510..70734) /locus_tag="ClothDRAFT_0704" CDS complement(70510..70734) /locus_tag="ClothDRAFT_0704" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428737.1" /db_xref="GI:256003749" /translation="MNLINTGKLDMALLSISSEKPRLFEKGEEMFWDDEHISKGMLEA HLKKEIYSDFTGKEYTDNSESIAIIAENNG" gene complement(70828..71403) /locus_tag="ClothDRAFT_0705" CDS complement(70828..71403) /locus_tag="ClothDRAFT_0705" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428738.1" /db_xref="GI:256003750" /translation="MFNTILWSKYSYNYSIHKYYAHQLLGYDYFSAMSGLILHSRDQL ENIINRKSITYREADMLYTGFDTLNVGFNTYYVNYTWVYGNEQFKEIYNQPDFYWSNF AQMMTPIVNFFGELKATAEGKEELALGSEEIEKLKIVLQTADKLIEVFNKYYVDLEEP LEVVIDSHYLQLKELVEYFGRRDNNLYKLEK" gene complement(71403..71510) /locus_tag="ClothDRAFT_0706" CDS complement(71403..71510) /locus_tag="ClothDRAFT_0706" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428739.1" /db_xref="GI:256003751" /translation="MINKLNNMIGKLNNVDKLAVYRYIIVILAVCLLCF" gene complement(71796..72629) /locus_tag="ClothDRAFT_0707" CDS complement(71796..72629) /locus_tag="ClothDRAFT_0707" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: pla:Plav_0428 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428740.1" /db_xref="GI:256003752" /translation="MNIKKLAIVIIFLCFGLLGCTANQKKEIPEPNNKIEKPKTENGN SSENEKTEDKTSQNDGKPTSEDMKESFTIDIGDGKHSFKVIMEARPFEEGENDEFYDS VLNISIYDVNDMSSPVQVIEDKTLDSLFKDYETVDANFDGYMDFCYVYNRGMANYYCK FWIWNPSSERFEESPGLSEISIPQFDNNSKVVKGYWRSSAAANETRYYKYIDGKLTCV RYLEMGDPDSEGMQTLVVKDYIDGELVEVFREKTLLTEDYKGEVYDRFFKWMDLNYHG G" sig_peptide complement(72561..72629) /locus_tag="ClothDRAFT_0707" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.439 at residue 23" gene complement(73000..74187) /locus_tag="ClothDRAFT_0708" CDS complement(73000..74187) /locus_tag="ClothDRAFT_0708" /inference="protein motif:PFAM:PF00155" /note="PFAM: aminotransferase class I and II; KEGG: sat:SYN_00908 aspartate aminotransferase" /codon_start=1 /transl_table=11 /product="aminotransferase class I and II" /protein_id="ZP_05428741.1" /db_xref="GI:256003753" /db_xref="InterPro:IPR001176" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /translation="MVVSKKALSISPSSTLAIDAKAKKMRSEGIDIIGFGAGEPDFDT PDHIKKAAIDAINAGFTKYTPASGTLELKQAICRKFKRDNGLDYNPSNIVISNGAKHS LVNALQAICNPGDEVIIPTPAWVSYPEMVKLADGVPVYIHCSEEEGFKFTIDKLEKAI TDKTRAIIINSPSNPTGMIYSEEELRAVADLAVSKGIYIISDEIYEKLIYDGYKHVSI ASFNDKIKDLTIVVNGVSKSYAMTGWRIGYTASNEQIAKIMANVQSHATSNPNSIAQK AALAALEGPQEIIDEMSAEFVKRRDYMVDRINSMNGVSCIKPNGAFYVMMNISKLIGK EIAGMKITGSDSFAEALLEKANVALVPGSGFGTDIHVRLSYATSMENIVEGLNRIEKF LSM" misc_feature complement(73009..74187) /locus_tag="ClothDRAFT_0708" /note="aspartate aminotransferase; Provisional; Region: PRK06836" /db_xref="CDD:180720" misc_feature complement(73015..74091) /locus_tag="ClothDRAFT_0708" /note="Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609" /db_xref="CDD:99734" misc_feature complement(order(73453..73455,73477..73482,73486..73488, 73573..73575,73666..73668,73816..73818,73888..73896)) /locus_tag="ClothDRAFT_0708" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99734" misc_feature complement(order(73357..73359,73366..73368,73453..73461, 73594..73596,73786..73788,73885..73887)) /locus_tag="ClothDRAFT_0708" /note="homodimer interface; other site" /db_xref="CDD:99734" misc_feature complement(73477..73479) /locus_tag="ClothDRAFT_0708" /note="catalytic residue; other site" /db_xref="CDD:99734" gene complement(74912..75847) /locus_tag="ClothDRAFT_0709" CDS complement(74912..75847) /locus_tag="ClothDRAFT_0709" /EC_number="3.4.13.19" /inference="protein motif:PRIAM:3.4.13.19" /note="PFAM: peptidase M19 renal dipeptidase; KEGG: similar to CG6154-PA, isoform A" /codon_start=1 /transl_table=11 /product="Membrane dipeptidase" /protein_id="ZP_05428742.1" /db_xref="GI:256003754" /db_xref="InterPro:IPR000180" /db_xref="InterPro:IPR006035" /db_xref="InterPro:IPR008257" /translation="MIIVDAHCDTITKIMEKGTQLRKNDCHVDIDRLKAKGNYVQFFA AFIDPAYCQAYALKRALQIIDEFYRQIEVNKDDIMICCNYNDIEEAVKANKIAAVLSI EGGEALQGDLGVLRMLYRLGVRSICLTWNHRNEIADGVKDESSGGGLTPFGREVVKEM NRLGMLIDLSHISKTGFWDVLECTSAPVIVSHSNAQRLCAHRRNLTDKQIMAVKDNGG VIGINLYPEFLNNSKEATIKDIINHIEYIASLAGPDHIGLGADFDGVDGLPAGINGVQ DIEKIFNELAKLNYSSENIEKFAGKNFLRVIQNVL" misc_feature complement(74930..75844) /locus_tag="ClothDRAFT_0709" /note="renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics...; Region: rDP_like; cd01301" /db_xref="CDD:30044" misc_feature complement(order(75056..75058,75065..75067,75239..75241, 75272..75274,75335..75337,75539..75541,75710..75712, 75821..75823,75827..75829)) /locus_tag="ClothDRAFT_0709" /note="active site" /db_xref="CDD:30044" misc_feature complement(order(75485..75490,75497..75502,75506..75511, 75641..75643,75653..75655,75662..75667,75671..75679, 75704..75706)) /locus_tag="ClothDRAFT_0709" /note="dimer interface; other site" /db_xref="CDD:30044" gene complement(76021..76695) /locus_tag="ClothDRAFT_0710" CDS complement(76021..76695) /locus_tag="ClothDRAFT_0710" /inference="protein motif:TFAM:TIGR00608" /note="TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; KEGG: sfu:Sfum_3283 DNA repair protein RadC" /codon_start=1 /transl_table=11 /product="DNA repair protein RadC" /protein_id="ZP_05428743.1" /db_xref="GI:256003755" /db_xref="InterPro:IPR001405" /translation="MVHEGHRKRLKERFLREGLDSFEQHQVLELLLFFSIPRKDTNEL AHTLLNRYGSLSGVFEADPKDLATTPGIGENSAILLSLIPHLSRRYLNDKWRDKPELN SSAKAGQYAISLFAGRNYEVFYVICLDAQNRVNYAELVHEGTINEAPVYPRIIVETAL RHKANSVILAHNHPGGTLNPSKADIEATKRIKAALEAISIKVVDHIIVCGGQYVSFAE KGLLSG" misc_feature complement(76030..76671) /locus_tag="ClothDRAFT_0710" /note="hypothetical protein; Reviewed; Region: PRK00024" /db_xref="CDD:178801" misc_feature complement(76045..76380) /locus_tag="ClothDRAFT_0710" /note="Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071" /db_xref="CDD:163702" misc_feature complement(order(76144..76146,76153..76155,76177..76179, 76183..76185,76333..76335)) /locus_tag="ClothDRAFT_0710" /note="MPN+ (JAMM) motif; other site" /db_xref="CDD:163702" misc_feature complement(order(76144..76146,76177..76179,76183..76185)) /locus_tag="ClothDRAFT_0710" /note="Zinc-binding site; other site" /db_xref="CDD:163702" gene complement(76834..77226) /locus_tag="ClothDRAFT_0711" CDS complement(76834..77226) /locus_tag="ClothDRAFT_0711" /inference="protein motif:PFAM:PF02021" /note="PFAM: protein of unknown function UPF0102; KEGG: dal:Dalk_4642 protein of unknown function UPF0102" /codon_start=1 /transl_table=11 /product="protein of unknown function UPF0102" /protein_id="ZP_05428744.1" /db_xref="GI:256003756" /db_xref="InterPro:IPR003509" /translation="MNSKVGNKNNKRAAGSIGEAAAVQFLKENNYEILETNFRYRRLG EIDIISREKDYICFVEVKARSSLGYGYPREAVNIRKQENIRRLAQIYLCKNRINDLKV RFDVVEVYMEKKGDDIEVKEISLIKNAF" misc_feature complement(76837..77205) /locus_tag="ClothDRAFT_0711" /note="Uncharacterized protein family UPF0102; Region: UPF0102; cl00516" /db_xref="CDD:186051" gene complement(77241..77525) /locus_tag="ClothDRAFT_0712" CDS complement(77241..77525) /locus_tag="ClothDRAFT_0712" /inference="similar to AA sequence:KEGG:C8J_0795" /note="KEGG: cju:C8J_0795 FlhB domain protein" /codon_start=1 /transl_table=11 /product="FlhB domain protein" /protein_id="ZP_05428745.1" /db_xref="GI:256003757" /db_xref="InterPro:IPR006135" /translation="MSGRKKIKQVAALKYSPEENNAPQIIGLGKGEIAEKILEKAKEN NIPIYENEELAAALNAMNIGDEIPPELYDIVAQILVFVGSVDKKYGEKKR" misc_feature complement(77250..77525) /locus_tag="ClothDRAFT_0712" /note="Flagellar biosynthesis pathway, component FlhB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhB; cl12017" /db_xref="CDD:187162" gene complement(77543..79177) /locus_tag="ClothDRAFT_0713" CDS complement(77543..79177) /locus_tag="ClothDRAFT_0713" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: Viral A-type inclusion protein repeat containing protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428746.1" /db_xref="GI:256003758" /translation="MRIESSENVLIQQTGALDILSRLDTGDTLRARVVDITANELLLK LFDGTLINAGTMTPIDAKKGELLDFIVKNKVNNQLFLEIMKDGVQNAAQPNVEDEIKN KLAQLGIKPDRRNMETAAELRANGTQLNAENITKVVDAVLRFKNLGIAKAAYLVSNNI IPEEKSITSLNRFVEGRVRLSSELLDLASSLAEIQDKDVAFAILKKLNAMDYPSQKSG ETSDVSTSPIHYENGKIYNSQKNWHIEGNVAQKSEKEHWSRKPELSRNGNIGTENLDK TVKNVDIEGNEILQLKKKTADFVNYKENIEKSEKELADFLNVILASQGSRSAGKGRSE TNNVAQVIKKSFEKMFAKINEEVEGRDINVKEFYRDIYKKLEIVRKVLEETDIPGKQE ILNKVDNIKSDINFLNELNKHTVYFQIPLKIFDKNTNGELYILKRNNGRKRIDPQNAT VFLSLDTENLGQVDSLISVNKKNVSLNFRLEKNEIIDYIKENYIQLYEGLAKKGYKLV DIKYRLIDEKVNLLNAREVLEKEIERTRNRGFDCKI" misc_feature complement(77624..77869) /locus_tag="ClothDRAFT_0713" /note="Flagellar hook-length control protein FliK; Region: Flg_hook; cl14669" /db_xref="CDD:187423" gene complement(79215..80000) /locus_tag="ClothDRAFT_0714" CDS complement(79215..80000) /locus_tag="ClothDRAFT_0714" /EC_number="3.1.26.4" /inference="protein motif:PRIAM:3.1.26.4" /note="PFAM: ribonuclease HII/HIII; KEGG: glo:Glov_2456 ribonuclease HII" /codon_start=1 /transl_table=11 /product="Ribonuclease H" /protein_id="ZP_05428747.1" /db_xref="GI:256003759" /db_xref="InterPro:IPR001352" /translation="MVQKKMGNMTVKQIEKSVEGLDLDKALEKLYCLKAEFGDRVDKI IEKYEKKKLKYEKELNRYLEMCIYEKEAYQRGYKLIAGIDEAGRGPLAGPVVAAAVIL PQDVFIEGLNDSKKLTENQREKLFDVINDKAIGVGIGIVDEKQIDEINILNATKKAMK LAVGNLKPVPDILFIDSLKLDDINIEQNSIVKGDAKSVSIAAASIIAKVTRDRILREM DKKYPMYGFARHKGYGTGEHIEAIKKYGICPIHRVSFTKNFIV" misc_feature complement(79236..79760) /locus_tag="ClothDRAFT_0714" /note="bacterial Ribonuclease HII-like; Region: RNaseH_typeII_bacteria_HII_like; cd07182" /db_xref="CDD:132879" misc_feature complement(order(79419..79421,79473..79475,79746..79751)) /locus_tag="ClothDRAFT_0714" /note="active site" /db_xref="CDD:132879" gene complement(80062..80715) /locus_tag="ClothDRAFT_0715" CDS complement(80062..80715) /locus_tag="ClothDRAFT_0715" /inference="protein motif:PFAM:PF06555" /note="PFAM: protein of unknown function DUF1121; KEGG: dal:Dalk_2774 protein of unknown function DUF1121" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1121" /protein_id="ZP_05428748.1" /db_xref="GI:256003760" /db_xref="InterPro:IPR009501" /translation="MAKSEEIIRERYKVMAPRIIKALNQRNFEAYFCETSEKAVECAL SLIPQGASVAWGGSMTLEEIGLIQRLKEGNYQVIDRDTAKSQEERFSLMRQALLSDVY LASVNAMSEDGIMVNIDGRGNRISAIAFGPKTVILVVGMNKICRDLESARKRAHTYAA PNNALRLGLELPCTKTGCCFDCNKNNPSSICAQIVEMHSSIVPGRIKVILVGENLGL" misc_feature complement(<80260..80688) /locus_tag="ClothDRAFT_0715" /note="Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139" /db_xref="CDD:31334" misc_feature complement(80083..80436) /locus_tag="ClothDRAFT_0715" /note="Uncharacterized ACR, YkgG family COG1556; Region: DUF162; cl00674" /db_xref="CDD:153927" gene complement(80735..81610) /locus_tag="ClothDRAFT_0716" CDS complement(80735..81610) /locus_tag="ClothDRAFT_0716" /inference="protein motif:PFAM:PF01926" /note="PFAM: GTP-binding protein HSR1-related; KEGG: par:Psyc_1982 ribosomal biogenesis GTPase" /codon_start=1 /transl_table=11 /product="GTP-binding protein HSR1-related protein" /protein_id="ZP_05428749.1" /db_xref="GI:256003761" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR006073" /translation="MNIQWFPGHMAKTRRILAENLKMVDVVVELLDARIPASSKNPEI DGIVKNKPKIVVLNKADLADEKISNEWSKWYNSQGYATIFIDSIKGTGIKQLKDQMRD IMKDRIERDRQRGRIFRPIRTMIVGIPNVGKSSLINKIAGKKSAVTGDRPGVTRNKQW INVNNEIQLMDTPGILWPKFEDKTVGINLAVTGAIKDEIIDTVELASILLEHLSKTYP ENIKKRYKLESLQDKKGYELLEEAGKKRGCIISGGEVDLTRIAAIVLDEFRGGKIGRI TLERPGDAVQELVAD" misc_feature complement(80750..81610) /locus_tag="ClothDRAFT_0716" /note="GTPase YlqF; Reviewed; Region: rbgA; PRK09563" /db_xref="CDD:181957" misc_feature complement(81083..81598) /locus_tag="ClothDRAFT_0716" /note="YlqF. Proteins of the YlqF family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases...; Region: YlqF; cd01856" /db_xref="CDD:57927" misc_feature complement(order(81089..81091,81206..81226,81347..81355, 81425..81430,81434..81439)) /locus_tag="ClothDRAFT_0716" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:57927" misc_feature complement(81428..81439) /locus_tag="ClothDRAFT_0716" /note="G4 box; other site" /db_xref="CDD:57927" misc_feature complement(81347..81355) /locus_tag="ClothDRAFT_0716" /note="G5 box; other site" /db_xref="CDD:57927" misc_feature complement(81209..81232) /locus_tag="ClothDRAFT_0716" /note="G1 box; other site" /db_xref="CDD:57927" misc_feature complement(81134..81157) /locus_tag="ClothDRAFT_0716" /note="Switch I region; other site" /db_xref="CDD:57927" misc_feature complement(81146..81148) /locus_tag="ClothDRAFT_0716" /note="G2 box; other site" /db_xref="CDD:57927" misc_feature complement(81089..81100) /locus_tag="ClothDRAFT_0716" /note="G3 box; other site" /db_xref="CDD:57927" misc_feature complement(81086..81094) /locus_tag="ClothDRAFT_0716" /note="Switch II region; other site" /db_xref="CDD:57927" gene complement(81635..82300) /locus_tag="ClothDRAFT_0717" CDS complement(81635..82300) /locus_tag="ClothDRAFT_0717" /inference="protein motif:TFAM:TIGR02227" /note="TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: dal:Dalk_1369 signal peptidase I" /codon_start=1 /transl_table=11 /product="signal peptidase I" /protein_id="ZP_05428750.1" /db_xref="GI:256003762" /db_xref="InterPro:IPR000223" /db_xref="InterPro:IPR011056" /translation="MEFKKKPAGIDKNHENELKKKFGTNFQAEKPKYFKEIVKWILLI VVALFTALLLRAYVFEWVVVQGQSMENTLYNNEVLFVSKLNYDRPKRGDIVIIQIYEG NWDYLAFFKDIPLFRTLFPSQGEVNYIKRVVGLPGDEIDIRDGYLYINGEKQQEPYTK GLTYEQSFELPRVVPENKVFVMGDNREYSKDSRQLGFIGFERIKGKAIFRVKPLKSFG SIY" misc_feature complement(81659..82183) /locus_tag="ClothDRAFT_0717" /note="signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227" /db_xref="CDD:162773" misc_feature complement(81680..82123) /locus_tag="ClothDRAFT_0717" /note="The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530" /db_xref="CDD:119398" misc_feature complement(order(81911..81913,82097..82099)) /locus_tag="ClothDRAFT_0717" /note="Catalytic site; other site" /db_xref="CDD:119398" gene complement(82455..82799) /locus_tag="ClothDRAFT_0718" CDS complement(82455..82799) /locus_tag="ClothDRAFT_0718" /inference="protein motif:TFAM:TIGR01024" /note="TIGRFAM: ribosomal protein L19; PFAM: ribosomal protein L19; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="ribosomal protein L19" /protein_id="ZP_05428751.1" /db_xref="GI:256003763" /db_xref="InterPro:IPR001857" /translation="MDIIKAIEQEQLKKDVPDFSIGDYVRVNVKVKEGNRERIQAFEG TVIAKKGSGISETFTVRRISYGVGVERIFPVHSPRVAGIEVIRKGKVRRAKLYYLRER VGKSAKVKTKLE" misc_feature complement(82461..82799) /locus_tag="ClothDRAFT_0718" /note="Ribosomal protein L19; Region: Ribosomal_L19; cl00406" /db_xref="CDD:185974" gene complement(82950..83690) /locus_tag="ClothDRAFT_0719" CDS complement(82950..83690) /locus_tag="ClothDRAFT_0719" /EC_number="2.1.1.31" /inference="protein motif:TFAM:TIGR00088" /note="KEGG: sat:SYN_00768 tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase" /codon_start=1 /transl_table=11 /product="tRNA (guanine-N1)-methyltransferase" /protein_id="ZP_05428752.1" /db_xref="GI:256003764" /db_xref="InterPro:IPR002649" /db_xref="InterPro:IPR016009" /translation="MRFDVLTLFPEVFDAVLGESIIGRARKNNIIQINTINIRDFSTN KHRKVDDYPYGGGGGMVMMAQPIYDAYLSIAEKLSYKPRVIYLSPQGRVLNQQIVKEL SKENHLILLCGHYEGVDERIIEEIVDDEISIGDYVLTGGELPAMVLIDSVSRLIPGVL SSEESYSQESHYEGLLEYPQYTRPYEFCNRKVPDVLMSGHHENINRWRRQQSLKRTYL KRPDLFARLSLDETDKKLLEEALKETSE" misc_feature complement(82962..83690) /locus_tag="ClothDRAFT_0719" /note="tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407" /db_xref="CDD:185975" gene complement(83680..84204) /locus_tag="ClothDRAFT_0720" CDS complement(83680..84204) /locus_tag="ClothDRAFT_0720" /inference="protein motif:TFAM:TIGR02273" /note="TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; KEGG: gbm:Gbem_3429 16S rRNA processing protein RimM" /codon_start=1 /transl_table=11 /product="16S rRNA processing protein RimM" /protein_id="ZP_05428753.1" /db_xref="GI:256003765" /db_xref="InterPro:IPR002676" /db_xref="InterPro:IPR007903" /db_xref="InterPro:IPR011961" /translation="MIQYLQVGKIVNTHGIKGEVKAIPLTDNPRRFNKLKWAYVSKEI SNEMPKFDIVSVKHHKNFVILKFSGIDDMNAAEKLKEHFVIIDRKDAVKLPKDTFFIC DLIGMNVFDTEEKKLGVLTDVLSTGSNDVYVVKSDNNKEILIPALKSVVKKVCFEDNK MVVDLPQGLIDDEV" misc_feature complement(83692..84204) /locus_tag="ClothDRAFT_0720" /note="16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122" /db_xref="CDD:178881" misc_feature complement(83935..84189) /locus_tag="ClothDRAFT_0720" /note="RimM N-terminal domain; Region: RimM; pfam01782" /db_xref="CDD:145113" misc_feature complement(83698..83916) /locus_tag="ClothDRAFT_0720" /note="Photosynthetic reaction center (RC) complex, subunit H; RC is an integral membrane protein-pigment complex which catalyzes light-induced reduction of ubiquinone to ubiquinol, generating a transmembrane electrochemical gradient of protons used to...; Region: PRCH; cl09959" /db_xref="CDD:164180" gene complement(84321..84551) /locus_tag="ClothDRAFT_0721" CDS complement(84321..84551) /locus_tag="ClothDRAFT_0721" /inference="similar to AA sequence:KEGG:Dvul_2143" /note="KEGG: dvl:Dvul_2143 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428754.1" /db_xref="GI:256003766" /db_xref="InterPro:IPR004088" /translation="MKELLETIARALVDCPEDVYVNEVEGEKSVILELKVSKDDMGKV IGKQGRIAKAIRTVMKAAAVKENKRVSVEILQ" misc_feature complement(84327..84551) /locus_tag="ClothDRAFT_0721" /note="Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837; cl00794" /db_xref="CDD:186191" gene complement(84625..84870) /locus_tag="ClothDRAFT_0722" CDS complement(84625..84870) /locus_tag="ClothDRAFT_0722" /inference="protein motif:TFAM:TIGR00002" /note="TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; KEGG: sfu:Sfum_3039 ribosomal protein S16" /codon_start=1 /transl_table=11 /product="ribosomal protein S16" /protein_id="ZP_05428755.1" /db_xref="GI:256003767" /db_xref="InterPro:IPR000307" /translation="MAVKIRLKRMGAKKRPFYRVVVADSRYPRDGRFIEEIGTYNPLT EPSEIKIDTEKAQKWLKNGAQPTDTVRALLKKVGVIS" misc_feature complement(84649..84867) /locus_tag="ClothDRAFT_0722" /note="Ribosomal protein S16; Region: Ribosomal_S16; cl00368" /db_xref="CDD:185946" gene complement(84910..86250) /locus_tag="ClothDRAFT_0723" CDS complement(84910..86250) /locus_tag="ClothDRAFT_0723" /inference="protein motif:TFAM:TIGR00959" /note="KEGG: dol:Dole_2310 signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="signal recognition particle protein" /protein_id="ZP_05428756.1" /db_xref="GI:256003768" /db_xref="InterPro:IPR000897" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004125" /db_xref="InterPro:IPR004780" /db_xref="InterPro:IPR013822" /translation="MLFEGLSGKLQEAMKKLRGKGRVTEKDVKEMMREIKLALLEADV NFKVVKDFIGKVSERAVGQEVLESLTPGQQVIKIVHEELINLMGSANSKVTFSSKPPT IYMMVGLQGSGKTTTSGKLANLLRKQGKKPLLVACDVYRPAAIKQLQVVGSQLGIEVF SMGDKTNPVDIAKAAVEYAKSRQYDLVIIDTAGRLHINEELMEELQNIKEAVRPQEIL LVVDSMTGQDAVNVAESFNEKLGVDGIILTKLDGDTRGGAALSVKAVTGKPIKFIGMG EKLNDIEPFFPDRMASRILGMGDVLSLIEKAQEAFDEKKALELEKKMRTQQFTLEDFL EQMQQIKKMGPLNQLLAMIPGFNANVMKDIELDEKKMARVEAIIKSMTKEERNNPSII NGSRRKRIAAGSGTTVQEVNKLLKEFEEMKKMMKMMTEMGKRGKKGLKKFRMPF" misc_feature complement(85006..86244) /locus_tag="ClothDRAFT_0723" /note="signal recognition particle protein; Provisional; Region: PRK10867" /db_xref="CDD:182793" misc_feature complement(86002..86235) /locus_tag="ClothDRAFT_0723" /note="SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881" /db_xref="CDD:145830" misc_feature complement(85429..85947) /locus_tag="ClothDRAFT_0723" /note="The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115" /db_xref="CDD:48379" misc_feature complement(85906..85929) /locus_tag="ClothDRAFT_0723" /note="P loop; other site" /db_xref="CDD:48379" misc_feature complement(order(85495..85500,85507..85509,85672..85674, 85837..85839)) /locus_tag="ClothDRAFT_0723" /note="GTP binding site; other site" /db_xref="CDD:48379" misc_feature complement(85006..85272) /locus_tag="ClothDRAFT_0723" /note="Signal peptide binding domain; Region: SRP_SPB; pfam02978" /db_xref="CDD:145891" gene complement(86292..86645) /locus_tag="ClothDRAFT_0724" CDS complement(86292..86645) /locus_tag="ClothDRAFT_0724" /inference="protein motif:PFAM:PF04297" /note="PFAM: putative helix-turn-helix protein YlxM/p13 family protein; Sigma-70 region 4 type 2" /codon_start=1 /transl_table=11 /product="putative helix-turn-helix protein YlxM/p13 family protein" /protein_id="ZP_05428757.1" /db_xref="GI:256003769" /db_xref="InterPro:IPR007394" /db_xref="InterPro:IPR013249" /translation="MDKVYEAALLLDFYGQLLTKRQFEILDLYLNNDYSLGEIAEHLN ISRQGVYDNIKRGRAMLDRMEEKLGLVHKFLQQKNRALEILKDIKSIDISSMSVEDAK ILKRVEERIEEIVES" misc_feature complement(86394..86645) /locus_tag="ClothDRAFT_0724" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cl01055" /db_xref="CDD:186312" gene complement(86872..87159) /locus_tag="ClothDRAFT_0725" CDS complement(86872..87159) /locus_tag="ClothDRAFT_0725" /inference="protein motif:PFAM:PF01476" /note="PFAM: Peptidoglycan-binding LysM" /codon_start=1 /transl_table=11 /product="Peptidoglycan-binding LysM" /protein_id="ZP_05428758.1" /db_xref="GI:256003770" /db_xref="InterPro:IPR002482" /translation="MKKKYVLKNKRRFFVFVLFVLMGLTAVISRATSIYGYREPSYEA ITVKRGDTLWSIAENYNKRGDIRKYIYDIMILNNLEDCEIIEGMELKVIVE" sig_peptide complement(87064..87159) /locus_tag="ClothDRAFT_0725" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.964 at residue 32" misc_feature complement(86884..87027) /locus_tag="ClothDRAFT_0725" /note="Lysin domain, found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function; Region: LysM; cl00107" /db_xref="CDD:153515" gene 87359..88000 /locus_tag="ClothDRAFT_0726" CDS 87359..88000 /locus_tag="ClothDRAFT_0726" /EC_number="3.4.21.88" /inference="protein motif:TFAM:TIGR00498" /note="KEGG: scl:sce4469 LexA repressor; TIGRFAM: LexA repressor; PFAM: peptidase S24 and S26 domain protein; LexA DNA-binding domain protein" /codon_start=1 /transl_table=11 /product="SOS-response transcriptional repressor, LexA" /protein_id="ZP_05428759.1" /db_xref="GI:256003771" /db_xref="InterPro:IPR006197" /db_xref="InterPro:IPR006199" /db_xref="InterPro:IPR006200" /db_xref="InterPro:IPR011056" /translation="MQNKINEKQQKILDFLNEQIEKNGYPPSVREICNAVGFKSTSTV HSYLEKLRKQGLIQKDPSKPRALKVINNKKNSKTDEPKNIYSGKELVEVPIIGKVTAG QPILAVENIEDTFPLPLDFVQNSTVFMLRVQGDSMIEAGIFDNDYIVVKQQSTANNGD IVVALIDDEATVKTFYKEKGFIRLQPANKFYDPIIVRDNLSILGKVIGVFRKM" misc_feature 87368..87556 /locus_tag="ClothDRAFT_0726" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" misc_feature 87377..87997 /locus_tag="ClothDRAFT_0726" /note="LexA repressor; Validated; Region: PRK00215" /db_xref="CDD:178931" misc_feature 87740..87979 /locus_tag="ClothDRAFT_0726" /note="Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (...; Region: S24_LexA-like; cd06529" /db_xref="CDD:119397" misc_feature order(87764..87766,87875..87877) /locus_tag="ClothDRAFT_0726" /note="Catalytic site; other site" /db_xref="CDD:119397" gene complement(88129..88377) /locus_tag="ClothDRAFT_0727" CDS complement(88129..88377) /locus_tag="ClothDRAFT_0727" /inference="protein motif:TFAM:TIGR02383" /note="TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein core; KEGG: sit:TM1040_1356 RNA-binding protein Hfq" /codon_start=1 /transl_table=11 /product="RNA chaperone Hfq" /protein_id="ZP_05428760.1" /db_xref="GI:256003772" /db_xref="InterPro:IPR001163" /db_xref="InterPro:IPR005001" /translation="MVSKNNINLQDVFLNQVRKEHIPVTVYLTNGFQLKGTVKGFDNF TVVLDSEGRQQLIYKHAISTISPMKIVSLIFNDNNRSE" misc_feature complement(88165..88347) /locus_tag="ClothDRAFT_0727" /note="Hfq, an abundant, ubiquitous RNA-binding protein, functions as a pleiotrophic regulator of RNA metabolism in prokaryotes, required for transcription of some transcripts and degradation of others. Hfq binds small RNA molecules called riboregulators that...; Region: Hfq; cd01716" /db_xref="CDD:99753" misc_feature complement(order(88231..88284,88288..88308)) /locus_tag="ClothDRAFT_0727" /note="Sm1 motif; other site" /db_xref="CDD:99753" misc_feature complement(order(88177..88194,88198..88215,88219..88221, 88252..88254,88285..88296)) /locus_tag="ClothDRAFT_0727" /note="intra - hexamer interaction site; other site" /db_xref="CDD:99753" misc_feature complement(88279..88284) /locus_tag="ClothDRAFT_0727" /note="inter - hexamer interaction site; other site" /db_xref="CDD:99753" misc_feature complement(order(88204..88206,88243..88248,88252..88254)) /locus_tag="ClothDRAFT_0727" /note="nucleotide binding pocket; other site" /db_xref="CDD:99753" misc_feature complement(88183..88218) /locus_tag="ClothDRAFT_0727" /note="Sm2 motif; other site" /db_xref="CDD:99753" gene complement(88484..89425) /locus_tag="ClothDRAFT_0728" CDS complement(88484..89425) /locus_tag="ClothDRAFT_0728" /EC_number="2.5.1.8" /inference="protein motif:TFAM:TIGR00174" /note="KEGG: geo:Geob_3107 tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase" /codon_start=1 /transl_table=11 /product="tRNA delta(2)-isopentenylpyrophosphate transferase" /protein_id="ZP_05428761.1" /db_xref="GI:256003773" /db_xref="InterPro:IPR002627" /translation="MDNVLVIIGPTASGKTKLAIEIAKRANGEIISADSMQIYKYMDI GTAKTDEEEKEGIKHYLIDEVTPDEEFSVARFKELALKYIDEILSKGKLPIVAGGTGL YINSLIYNLEFSDTICDWELRKKLEQEAKEKGNEYLHNKLKEIDPKAAEKIHMNNVKR VIRAIEVYTYTKKPISVHQEESRKNPPRHNFILIGITMDREKLYDRINKRVDLMLEKG LVKEVEKLVEMGYDKSTIAMQGLGYKEILSYLRGERSLDEAVEILKRDTRRYAKRQMT WFRKIENVYWINKDEFDSDEKIIKNLKYYLATFGIFL" misc_feature complement(88517..89425) /locus_tag="ClothDRAFT_0728" /note="IPP transferase; Region: IPPT; cl00403" /db_xref="CDD:185972" gene complement(89443..91710) /locus_tag="ClothDRAFT_0729" CDS complement(89443..91710) /locus_tag="ClothDRAFT_0729" /inference="protein motif:TFAM:TIGR00585" /note="TIGRFAM: DNA mismatch repair protein MutL; PFAM: MutL dimerisation; DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; KEGG: sfu:Sfum_1919 DNA mismatch repair protein MutL" /codon_start=1 /transl_table=11 /product="DNA mismatch repair protein MutL" /protein_id="ZP_05428762.1" /db_xref="GI:256003774" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR013507" /db_xref="InterPro:IPR014762" /db_xref="InterPro:IPR014763" /db_xref="InterPro:IPR014790" /translation="MGRIIILDENTANQIAAGEVVERPASVVKELVENSIDAGSTNIS VEINNGGISFIKVVDNGSGIEEDDIEIAFERHATSKIRRASDLEAITSLGFRGEALAS IASVSTVEVTSRPAHREYGRYVKIQGGTVLESGQVGCPAGTTFIVRDLFYNTPARFKF LKKDSTEAGYVSDIVSRIALGNPDISFRLINNKNTVIHTPGNNDLLSTIYSLYGKETA KECMEISYEDETVKITGYAGSPEIARANRNYQSIYLNKRYIKNKVISSAIDEAYKTYL MKNKFAFIVLYIELNPLLVDVNVHPTKMEVRFSREQEIFRAVYHAVNNALLSKTHIRN VSLKDSPKNYFKFEQSSKKEADYVQQRLDTDRKFSGYNYDEDFKTEKTNTSKSTWENL IVKESANINKRKDESIDEVINKNEVGDKNKVISEDEVINKDEVINKDKVINKDKVINK GEVVNKVNVNEVKNESVDNLINGQISGLVNWAINEPINKTNDKLIEKSDGTALKGTGE ECYNFDKSGYDNILKDVSDKPKDNRNDVDNNADTNFEKIRDGKDTRPQQDIERNVFLD ARIIGQVFSTYILLQNEDDLIIIDQHAAHERIRFEELKEKYARNESLAQYLLTPVVIE LTNQEIVFLEEEKELFNKLGFIFESFGNNSIILRSVPIPDEGVGVKEAFLEVVDFLMS KGRKYDKIIEEDALYQIACKSAVKANKKLDEIEIKAILDKLNMLQNPYTCPHGRPTVV KITKYEFEKMFKRIV" misc_feature complement(<90394..91710) /locus_tag="ClothDRAFT_0729" /note="DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323" /db_xref="CDD:30671" misc_feature complement(91360..91641) /locus_tag="ClothDRAFT_0729" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature complement(order(91372..91374,91378..91380,91411..91422, 91519..91524,91528..91530,91534..91536,91540..91542, 91600..91602,91609..91611,91621..91623)) /locus_tag="ClothDRAFT_0729" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature complement(91609..91611) /locus_tag="ClothDRAFT_0729" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature complement(order(91414..91416,91420..91422,91522..91524, 91528..91530)) /locus_tag="ClothDRAFT_0729" /note="G-X-G motif; other site" /db_xref="CDD:28956" misc_feature complement(90733..91098) /locus_tag="ClothDRAFT_0729" /note="MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782" /db_xref="CDD:48466" misc_feature complement(90802..90804) /locus_tag="ClothDRAFT_0729" /note="ATP binding site; other site" /db_xref="CDD:48466" misc_feature complement(89578..90009) /locus_tag="ClothDRAFT_0729" /note="MutL C terminal dimerization domain; Region: MutL_C; cl07336" /db_xref="CDD:157790" gene complement(91780..94392) /locus_tag="ClothDRAFT_0730" CDS complement(91780..94392) /locus_tag="ClothDRAFT_0730" /inference="protein motif:TFAM:TIGR01070" /note="KEGG: sat:SYN_01405 DNA mismatch repair protein; TIGRFAM: DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS domain protein; MutS II domain protein; MutS IV domain protein; MutS III domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein" /codon_start=1 /transl_table=11 /product="DNA mismatch repair protein MutS" /protein_id="ZP_05428763.1" /db_xref="GI:256003775" /db_xref="InterPro:IPR000432" /db_xref="InterPro:IPR005748" /db_xref="InterPro:IPR007695" /db_xref="InterPro:IPR007696" /db_xref="InterPro:IPR007860" /db_xref="InterPro:IPR007861" /translation="MASLTPMMQQYLEIKEQYKDCILFFRLGDFYEMFFSDAEVASRE LEITLTGKDCGLEERAPMCGVPFHSADSYIAKLISKGYKVAICEQIEDPALAKGLVKR DVIRIVTPGTVTDSAMLDEKKNNYLMSIYKNKNYYGIACVDLTTGEFLSTHITFGNTF NKLMDEIAKFSPSEIVVNGEFFHDENIKKTLKQRFDVYISGLEDKFFEKEFSIQKVRN YFKDYVIEENAFDLYINASGALLEYLEQTQKVNLSHIQNFNVYRIEEYMILDMATRRN LELTETMREKNRKGSLLWVLDRTMTSMGGRTLRKWIEQPLINLHDIKDRLDAVNEFKE RFMIRSEVRELLRAVYDIERLMTKVILGSANCRDLISIKHSIGQVPYIKELLRDLKAD LNVLSYNELDTLTDVYEIIDKAIVDDPPVAVKEGGIIKEGFNEEVDRLRSASKDGKKW IAHLESKERERTGIKNLKVGFNKVFGYYIEVTKSYYSQVPDDYIRKQTLANCERYITP ELKEIENTVLGAEDRLVELEYQIFVDVRNKVAKEINRLKTTARSLARIDVLCSLAEVA DRESYTMPEVTDDDKIEIKDGRHPVVEKIIGQEAFVPNDTYLDMDENQIAIITGPNMA GKSTYMRQVALIVLMAQIGSFVPAKSAKIGIVDRIFTRVGASDDLAAGQSTFMVEMSE VANILGNATSKSLLVLDEIGRGTSTYDGLSIAWAVIEYIGEKIGARTLFATHYHELTE LEERIEGIKNYCISVEEKGEDIIFLRKILRGGADNSYGVQVARLAGIPDPVIHRAKEI LKKLEDADITRKEKRITRRKQPIEGQIDVFTFNAAQRSYDEVLNELKSLDITTLTPLD AINVLYNLQKKVKG" misc_feature complement(91783..94392) /locus_tag="ClothDRAFT_0730" /note="DNA mismatch repair protein MutS; Provisional; Region: PRK05399" /db_xref="CDD:180056" misc_feature complement(94042..94380) /locus_tag="ClothDRAFT_0730" /note="MutS domain I; Region: MutS_I; pfam01624" /db_xref="CDD:144998" misc_feature complement(93625..94020) /locus_tag="ClothDRAFT_0730" /note="MutS domain II; Region: MutS_II; pfam05188" /db_xref="CDD:147397" misc_feature complement(92692..93603) /locus_tag="ClothDRAFT_0730" /note="MutS domain III; Region: MutS_III; cl04977" /db_xref="CDD:156416" misc_feature complement(91996..92646) /locus_tag="ClothDRAFT_0730" /note="MutS1 homolog in eukaryotes. The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family possess C-terminal...; Region: ABC_MutS1; cd03284" /db_xref="CDD:73043" misc_feature complement(92512..92535) /locus_tag="ClothDRAFT_0730" /note="Walker A/P-loop; other site" /db_xref="CDD:73043" misc_feature complement(order(92191..92193,92293..92298,92401..92403, 92509..92517,92521..92526)) /locus_tag="ClothDRAFT_0730" /note="ATP binding site; other site" /db_xref="CDD:73043" misc_feature complement(92401..92412) /locus_tag="ClothDRAFT_0730" /note="Q-loop/lid; other site" /db_xref="CDD:73043" misc_feature complement(92347..92388) /locus_tag="ClothDRAFT_0730" /note="ABC transporter signature motif; other site" /db_xref="CDD:73043" misc_feature complement(92293..92310) /locus_tag="ClothDRAFT_0730" /note="Walker B; other site" /db_xref="CDD:73043" misc_feature complement(92275..92286) /locus_tag="ClothDRAFT_0730" /note="D-loop; other site" /db_xref="CDD:73043" misc_feature complement(92185..92205) /locus_tag="ClothDRAFT_0730" /note="H-loop/switch region; other site" /db_xref="CDD:73043" gene complement(94424..94816) /locus_tag="ClothDRAFT_0731" CDS complement(94424..94816) /locus_tag="ClothDRAFT_0731" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428764.1" /db_xref="GI:256003776" /translation="MDIFTKAKELGELISNSDEMTNYKKWEASLERDHKARAILREYQ YLQTEMVRAAQEDKDKSVIDDIKERLLSKFDEINNNEITRNYIESKEKLDRLIKKVND VLVYSISGEEPCPSDDCSSCSGCRNKSL" misc_feature complement(94484..94813) /locus_tag="ClothDRAFT_0731" /note="Protein of unknown function (DUF964); Region: DUF964; cl01483" /db_xref="CDD:186436" gene complement(94960..96312) /locus_tag="ClothDRAFT_0732" CDS complement(94960..96312) /locus_tag="ClothDRAFT_0732" /inference="protein motif:PFAM:PF07833" /note="PFAM: copper amine oxidase domain protein; SCP-like extracellular; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="copper amine oxidase domain protein" /protein_id="ZP_05428765.1" /db_xref="GI:256003777" /db_xref="InterPro:IPR012854" /db_xref="InterPro:IPR014044" /translation="MKKLMLKRLALFLTVFTVLFSIGAFDIYSLSDIKICVNGQYLQL DVPPVIENGRTLVPVRGVFESINADVEWVPESKKVNVYKNDIVITLKINSNIAYINDN AVRLDVPARIVGGRTLVPVRFISESIGASVGWDDATRTVIINTYDENVEDEDPETQEF VFDGKVSTLIGASLSDVIETFGEPDRIDLSKYGFDWYIYNNNLLKYIQIGIEDDKVVG VFTNSPYYRLNEAIGVGTDGISAEKELGKPLEYIKKGNTYYMMKNSNEQKVFNVNDQY FVTVFFDIFDENKVTSYLLIDCETERALHGYYGKPSEELRISFEREVFDLANTVRARY GLKPFEWDDEIAKVARAHSEDMVLNNYFSHTNLQGESPFDRMKKAGISYSSAGENIAM GQTEAIFAHEGWMNSQGHRLNILGNFERLGVGVYIGNENEITYTQNFYTPMRFNKFFY " sig_peptide complement(96238..96312) /locus_tag="ClothDRAFT_0732" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.756 at residue 25" misc_feature complement(95884..96162) /locus_tag="ClothDRAFT_0732" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature complement(94993..95355) /locus_tag="ClothDRAFT_0732" /note="SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379" /db_xref="CDD:88558" gene complement(96418..97101) /locus_tag="ClothDRAFT_0733" CDS complement(96418..97101) /locus_tag="ClothDRAFT_0733" /inference="protein motif:TFAM:TIGR01509" /note="TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mfa:Mfla_1729 HAD family hydrolase" /codon_start=1 /transl_table=11 /product="HAD-superfamily hydrolase, subfamily IA, variant 3" /protein_id="ZP_05428766.1" /db_xref="GI:256003778" /db_xref="InterPro:IPR000235" /db_xref="InterPro:IPR005833" /db_xref="InterPro:IPR005834" /db_xref="InterPro:IPR006402" /translation="MAMKKYKISLVIFDMDGLMFDTERIGVLGWHEAAKSFGIEIKQE FLRDMTGLNVKSIEKVFKKYYGNDLPFYDIRDLRVKYVLDYIEKNGMPVKPGLFELLD YLDHRGIMKAVATSTERKRTEKYLTLAGIRERFDAIVCGDEVERGKPEPDIFLEAARR TGKRPEECIVLEDSANGIKAASRAKMFPVLIPDIRRPDEVEELVYRELKSLHEVINLL ESLKEEVVL" misc_feature complement(96445..97083) /locus_tag="ClothDRAFT_0733" /note="Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637" /db_xref="CDD:30982" misc_feature complement(96529..96819) /locus_tag="ClothDRAFT_0733" /note="Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others...; Region: HAD_like; cd01427" /db_xref="CDD:119389" misc_feature complement(96757..96759) /locus_tag="ClothDRAFT_0733" /note="motif II; other site" /db_xref="CDD:119389" gene complement(97163..97651) /locus_tag="ClothDRAFT_0734" CDS complement(97163..97651) /locus_tag="ClothDRAFT_0734" /inference="protein motif:PFAM:PF00583" /note="PFAM: GCN5-related N-acetyltransferase; KEGG: bja:blr3791 hypothetical protein" /codon_start=1 /transl_table=11 /product="GCN5-related N-acetyltransferase" /protein_id="ZP_05428767.1" /db_xref="GI:256003779" /db_xref="InterPro:IPR000182" /translation="MKFIKADFKDVEVIHSIVHSTIKEVYPKYYPEGVVDFFLTHHSL ENIKKAVNIEFILLIECDGEIVGTGAIYENQIKRMFVLPEFQGKGYGSMLLDRLEQQA ANKGYANVVLDSSLPAYSLYEKRGYVPIEYNKIVTKNGHVLCFHKMSKMLVKAEKLKE EV" misc_feature complement(97190..>97537) /locus_tag="ClothDRAFT_0734" /note="amino-acid N-acetyltransferase; Region: N-Ac-Glu-synth; TIGR01890" /db_xref="CDD:162583" misc_feature complement(97313..97486) /locus_tag="ClothDRAFT_0734" /note="N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301" /db_xref="CDD:173926" misc_feature complement(order(97376..97381,97409..97417)) /locus_tag="ClothDRAFT_0734" /note="Coenzyme A binding pocket; other site" /db_xref="CDD:173926" gene complement(97818..99941) /locus_tag="ClothDRAFT_0735" CDS complement(97818..99941) /locus_tag="ClothDRAFT_0735" /inference="protein motif:PFAM:PF00015" /note="PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: shn:Shewana3_3611 methyl-accepting chemotaxis sensory transducer" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis sensory transducer" /protein_id="ZP_05428768.1" /db_xref="GI:256003780" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /translation="MKPEKIKNYIMDKLSRCKLSEIKLLSNAKKPDLNDSFKKDEKTD GQRYKILKNIGRLIDFKSLKTKLLLLNTVTILFVIIIIMIYMIHVSRSNAEENMKNNL KNQSVAAEIILNNEISNIKNLNVNIAKNSAFRMLIQMNLKEQLIQSLQEYMNKYPEIN DIIVYKGDTEIYRANEKSNIKIDNTVMQRSGFVQGDHINVYSIEDIVDSNSETIGTIV MLHDITAGNNLIKKISTSLETNAFLYEGNKLVAMSDSNGNAYDNNEDVTIDLESIEKG NEFLSSAQRIFDGNYYLYCKEIKDYQGKTLGVLSVGVTDKSLKELVNEITYNMIGIGL LSLVIGLFLAWIVSVLISTPIKQLVRNVELVQKGDLTVSSDYKSNDEVGMLSNAFYEM VATLKAILTDINEKSLLLSRSSEEINNRCSMSMSTFEGISSAAQDIAQGTNEQVEAVD EAKKQMEVILSDMAKMADFLTETREVSLNAGESASMGDKLVTEALNQMDNINDSILNS NKCLKELGRESDNIFKIIKVISDIASQTHLLAMNATIEAAKAGEAGKGFSVIASEIRK LALKSKDSTVEINKIISDIKTYINKTINIADATIAQSEKGILVVSDAKNAFNMINNNT RDIIEKVNDLVVVTERVVSSSKLFTKSFYQTMEVAESTSASIEEIAASLETQTETMDK ITNSSSLLAQSAKDMHELVGKFKIN" misc_feature complement(98748..>98912) /locus_tag="ClothDRAFT_0735" /note="Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The...; Region: HAMP; cl01054" /db_xref="CDD:154171" misc_feature complement(97827..98651) /locus_tag="ClothDRAFT_0735" /note="Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283" /db_xref="CDD:128579" misc_feature complement(97821..98465) /locus_tag="ClothDRAFT_0735" /note="Taxis toward Aspartate and Related amino acids and Homologs (TarH). The Tar chemoreceptor of Escherichia coli mediates attractant responses to aspartate, maltose, and phenol, repellent responses to Ni2+ and Co2+, and thermoresponses. These...; Region: TarH; cl00144" /db_xref="CDD:153541" gene complement(100109..101281) /locus_tag="ClothDRAFT_0736" CDS complement(100109..101281) /locus_tag="ClothDRAFT_0736" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: pca:Pcar_1057 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428769.1" /db_xref="GI:256003781" /translation="MKMAFSNKWKCALLFAVTLSLIFTAACASKPKAETITPNQESQK NTSNLDSEKEVIQTEQGQENSGQTNRLDNTGKKIAFVTFANPDSQEWQKLAENAAFRV LKEAGYDTENTEFKIIKEDDATKVGEVTKEIMQFSPDLALVINSSIAIPLAKSLEGAP FPVVIPSCREAGVIDSSGVAAKNVTGVNFTPVDILAKAANLVSVVDPSIPKKTVFIIG KYAPAKYPKEMVESQLKAAGVELKAYEVPETEEELYSVIEKYENDPEIKWVIYVGNFV RLKDGTVGNLTDALTYLRENSKKINIALVDSMVKYGAFGGVTVDLTALAEQQTEIAVR LLNGEDIKSIKIEDPKKVYIYYNKMTADRIGVELPLQAIESAYRVYTDYEGNYIGN" sig_peptide complement(101195..101281) /locus_tag="ClothDRAFT_0736" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.799 at residue 29" misc_feature complement(100178..100975) /locus_tag="ClothDRAFT_0736" /note="Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011" /db_xref="CDD:186883" gene complement(101671..103113) /locus_tag="ClothDRAFT_0737" CDS complement(101671..103113) /locus_tag="ClothDRAFT_0737" /inference="protein motif:TFAM:TIGR00089" /note="KEGG: gur:Gura_3127 RNA modification protein; TIGRFAM: RNA modification enzyme, MiaB family; tRNA-i(6)A37 thiotransferase enzyme MiaB; PFAM: Protein of unknown function UPF0004 ; Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB" /codon_start=1 /transl_table=11 /product="RNA modification enzyme, MiaB family" /protein_id="ZP_05428770.1" /db_xref="GI:256003782" /db_xref="InterPro:IPR002792" /db_xref="InterPro:IPR005839" /db_xref="InterPro:IPR006463" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013848" /translation="MSKGTRDRKNIYVSPEEMARQQRFIDEIKELNYRKEVKTGKKKL YCLNTFGCQMNEHDSEKLAGMLAEMGYAETDNVNESDLVIYNTCCVRENAELKVYGHL GMLKPLKNQKPDLVIAVCGCMMQQPEVVEHIKKTYSHVDLIFGTHNLYKFPELLYSAM DSQTTVVDVWDCDGQIAENVAIERKDGVKAWVTVMYGCNNFCTYCIVPYVRGRERSRS MDDILEEVRMLGRQGFKEITLLGQNVNSYGKDIGDGTSFAELIREVNKIPGIERIRFT TSHPKDLSDDLIYAMRDCEKVCEHLHLPFQAGSTRILKLMNRKYTKEDYINLVAKIKE NIPDIALTTDIIVGFPGETEEDFSDTLDILEKVRFDNAYTFLYSKRTGTPAAKMEDQV PEEVKKERFQRLLETQNRISKEINDTFLGKVVEVLVEGVSKTNDKIFTGRTRGNKVVN FEADASLIGKLVNVRINTVKTWSLEGSIVR" misc_feature complement(101674..102990) /locus_tag="ClothDRAFT_0737" /note="(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14328" /db_xref="CDD:184625" misc_feature complement(102679..102981) /locus_tag="ClothDRAFT_0737" /note="Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919" /db_xref="CDD:144496" misc_feature complement(101929..102528) /locus_tag="ClothDRAFT_0737" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature complement(order(101983..101988,102076..102078, 102202..102204,102280..102288,102355..102360, 102394..102396,102496..102504,102508..102510, 102514..102516,102520..102522)) /locus_tag="ClothDRAFT_0737" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene complement(103175..104050) /locus_tag="ClothDRAFT_0738" CDS complement(103175..104050) /locus_tag="ClothDRAFT_0738" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428771.1" /db_xref="GI:256003783" /translation="MVKNNEKLIKWLFDTNAIRVCPKDKPFWYTSGTIGPYYINTHFL YGSEEKANKLLEFIDKEKENILKCPDRILEETMKNYQSDPIYRGLIDEMCDFIKNNID VNEVDYISGGERRDWFFSPIIAKLLNKPHITIYKDLTTVVSSDGKTEELKELNGESVL HIADLITEASSYERAWIPAIKNNGGRIKWSVVVVDRKQGGAELLKSYDIKSFSMVDID IGLFKRVLDMGLIDREQFEMIEQYILDPKESMAKFLRKNPEFIKQALMADDKTRERAK LCIEKDFYGLNIELS" misc_feature complement(103307..104050) /locus_tag="ClothDRAFT_0738" /note="Phosphoribosyl transferase domain; Region: Pribosyltran; cl00309" /db_xref="CDD:185893" gene 104501..104803 /locus_tag="ClothDRAFT_0739" CDS 104501..104803 /locus_tag="ClothDRAFT_0739" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428772.1" /db_xref="GI:256003784" /translation="MMSSSRLISCNRDWTGITVLDKKGKPIFLDYHQISEIRFGYHTI TKLFSKKTSEKIEIRLKDSTKPILVLKPMDWDRFDQYKQEITRFAKENRIRLVEYE" gene complement(105012..106094) /locus_tag="ClothDRAFT_0740" CDS complement(105012..106094) /locus_tag="ClothDRAFT_0740" /inference="protein motif:TFAM:TIGR01357" /note="TIGRFAM: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; KEGG: gur:Gura_1820 3-dehydroquinate synthase" /codon_start=1 /transl_table=11 /product="3-dehydroquinate synthase" /protein_id="ZP_05428773.1" /db_xref="GI:256003785" /db_xref="InterPro:IPR002658" /db_xref="InterPro:IPR016037" /translation="MIKLNVNLQDRSYPIYISTDYSQIGKCIQSAKLTGKMVLITDTN VDKYQAEECVKAFSDAGYEVSKFVIPAGEENKNLDTTRDIYKYLLGLKLDRSATLMAL GGGVVGDITGFAAATFLRGINFVQIPTTLLAQSDSSVGGKVGVDFEGTKNIIGAFYQP KFVYINVNTLKTLPERELKAGLAEVVKHGVIMDEEFYEYIDYNVHKILNHDEAVLQYI AKRNCSIKASVVEKDEKEGGLRAILNFGHTIGHAIETVMNFELLHGECVSLGMVGAMR MALHLEMIDEQSVNRVKNTLDKIGLPTRLEGIDVDKVYNQMFYDKKIKGSKLTFVLPR KRIGEVIQCTIDDEDLIKRVIASLGE" misc_feature complement(105039..106061) /locus_tag="ClothDRAFT_0740" /note="Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195" /db_xref="CDD:173954" misc_feature complement(order(105306..105308,105342..105344, 105354..105356,105531..105533,105543..105545, 105564..105566,105588..105590,105633..105635, 105642..105644,105699..105701,105705..105710, 105759..105761,105768..105770,105777..105785, 105969..105971)) /locus_tag="ClothDRAFT_0740" /note="active site" /db_xref="CDD:173954" misc_feature complement(order(105624..105641,105666..105671, 105735..105743,105747..105749,105756..105758, 105837..105842,105861..105863)) /locus_tag="ClothDRAFT_0740" /note="dimer interface; other site" /db_xref="CDD:173954" misc_feature complement(order(105306..105308,105354..105356, 105543..105545)) /locus_tag="ClothDRAFT_0740" /note="metal-binding site" /db_xref="CDD:173954" gene complement(106173..108968) /locus_tag="ClothDRAFT_0741" CDS complement(106173..108968) /locus_tag="ClothDRAFT_0741" /inference="protein motif:TFAM:TIGR00392" /note="TIGRFAM: isoleucyl-tRNA synthetase; KEGG: geo:Geob_0392 isoleucyl-tRNA synthetase" /codon_start=1 /transl_table=11 /product="isoleucyl-tRNA synthetase" /protein_id="ZP_05428774.1" /db_xref="GI:256003786" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002300" /db_xref="InterPro:IPR002301" /db_xref="InterPro:IPR010663" /db_xref="InterPro:IPR013155" /db_xref="InterPro:IPR015413" /db_xref="InterPro:IPR015905" /translation="MAEDYGKTLNLPNTDFPMRANLPQREPEFLKKWEEMDIYHKQLK KNAGKPKFVLHDGPPYANGGIHLGTALNKILKDIIIKYYSMKGYETPYVPGWDTHGLP IEQRAIKEFGLKRHEVSPVEFRQACKKFALKYLDVQREAFKRLGVRADWDNPYITLNK EFEAKQIEVFGEMAKKGYIYKGLRPVYWCPECETALAEAEIEYAEDTTLSIYVKFEVK DDKGKFGGLVDSLKNTYFVIWTTTTWTLPGNLAICLNGEFEYGLVKANGEYYIIALEL LENVMKVAGIEEYEVKAKFTGAELEGMLCRHPFLDRDSVIILGDHVTAEAGTGCVHTA PGHGAEDFEVCKKYDIPVIVPVDDKGYLTSEAGQFAGLYYEKSNAAIIEQLKSTNNLL ASEKIVHQYPHCWRCKDPIIFRATEQWFASIEGFRKEAIDAISTVKWIPEWGQERITN MVRERGDWCISRQRIWGVPIPIFYCKDCKKELINDDTIKAVAKLFAEKGSDAWYEYDA KDILPEGTKCECGCKEFTKEKDIMDVWFDSGSSHAAVLETTEGLTWPADMYLEGSDQH RGWFQSSLLTAVATKGQAPYKTVLTHGYVVDGEGRKMSKSLGNGIDPEDVIKEYGADI LRLWVASSDYRTDIRISKDILKQLSEVYRKIRNTCRYILGNIYDFDPNKDMVSYDEMN ELDKWALMKLNGLIKKVNDAYEKYEFHLMFHAIHNFCVVDMSNFYLDIIKDRLYTSRA DSKERRSAQTAMYEILEALVKMLAPVLAFTSEEVWQFMPHRSTNDPESVQLNYWPEPN EKYENAALKEKWDRIIEIRDVVSKALEIARTEKIIGHSLNAKVTIFADKENYDFIEPI KKDLVTVFIVSDFELKGYDEASDGKYYEDPDVKGIRVNISMASGSKCERCWMISESVG KNEKHPTLCDRCAEVVG" misc_feature complement(106179..108959) /locus_tag="ClothDRAFT_0741" /note="isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743" /db_xref="CDD:180231" misc_feature complement(<108405..108821) /locus_tag="ClothDRAFT_0741" /note="catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818" /db_xref="CDD:173909" misc_feature complement(108762..108773) /locus_tag="ClothDRAFT_0741" /note="HIGH motif; other site" /db_xref="CDD:173909" misc_feature complement(107049..>107741) /locus_tag="ClothDRAFT_0741" /note="catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818" /db_xref="CDD:173909" misc_feature complement(order(107058..107060,107154..107171, 107181..107195,107262..107264,107268..107270, 107274..107288,107355..107357,107364..107366, 107628..107630)) /locus_tag="ClothDRAFT_0741" /note="active site" /db_xref="CDD:173909" misc_feature complement(107151..107165) /locus_tag="ClothDRAFT_0741" /note="KMSKS motif; other site" /db_xref="CDD:173909" misc_feature complement(106509..107051) /locus_tag="ClothDRAFT_0741" /note="Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960" /db_xref="CDD:153414" misc_feature complement(order(106515..106517,106773..106775, 106782..106784,106794..106796,106809..106811, 106818..106823,106830..106835,106842..106844, 106986..106991,106998..107000,107007..107009, 107019..107021,107028..107030,107040..107042)) /locus_tag="ClothDRAFT_0741" /note="tRNA binding surface; other site" /db_xref="CDD:153414" misc_feature complement(order(106989..106991,106998..107000)) /locus_tag="ClothDRAFT_0741" /note="anticodon binding site; other site" /db_xref="CDD:153414" misc_feature complement(106182..106271) /locus_tag="ClothDRAFT_0741" /note="Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827" /db_xref="CDD:148438" gene complement(109369..109833) /locus_tag="ClothDRAFT_0742" CDS complement(109369..109833) /locus_tag="ClothDRAFT_0742" /inference="protein motif:PFAM:PF05103" /note="PFAM: DivIVA family protein; KEGG: gur:Gura_1166 DivIVA family protein" /codon_start=1 /transl_table=11 /product="DivIVA family protein" /protein_id="ZP_05428775.1" /db_xref="GI:256003787" /db_xref="InterPro:IPR007793" /translation="MNYTPNDLENLTFKRSVVGGYSEDMVNEVLDKIIEDYVAYIREN IELKDKVAMLNEAIAHYKNIEESLQNTLLMAQQTSEEIKRNSYQKAENIIKEAEIKAQ KMIDEANQEVLKIKFEYEELKRKLHSYKSKVESLLLSQLEILKPIVEEEEAE" misc_feature complement(109435..109827) /locus_tag="ClothDRAFT_0742" /note="DivIVA protein; Region: DivIVA; pfam05103" /db_xref="CDD:147333" misc_feature complement(109723..109824) /locus_tag="ClothDRAFT_0742" /note="DivIVA domain; Region: DivI1A_domain; TIGR03544" /db_xref="CDD:163317" gene complement(109847..110638) /locus_tag="ClothDRAFT_0743" CDS complement(109847..110638) /locus_tag="ClothDRAFT_0743" /inference="protein motif:PFAM:PF01479" /note="PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: RNA-binding S4 domain-containing protein" /codon_start=1 /transl_table=11 /product="RNA-binding S4 domain protein" /protein_id="ZP_05428776.1" /db_xref="GI:256003788" /db_xref="InterPro:IPR002942" /translation="MNKEVILRGISKAEDKLLVARILDKYTLSQKIMSYTHSDFLDPY QQNVVRKCLEMSGIRDHVFYGGFSGAERTVVVFCPYYMPENIESEFSGFFEILKIKPN TRENFSHRDYLGSLMGLGIKREKIGDILVREDFAFVVVLKDIADYIRINLTKVGNARV EIDIVNPDELDILEPKVKEISSTVASLRLDSVASAGFGISRSKTADLIRGEKVAVNWE TATNPARLVKEGDTISIRGKGRVVVEKVGNTTKKDRIHILLKKFI" misc_feature complement(109850..110605) /locus_tag="ClothDRAFT_0743" /note="Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302" /db_xref="CDD:32457" misc_feature complement(109934..110080) /locus_tag="ClothDRAFT_0743" /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940" /db_xref="CDD:186878" gene complement(110665..110949) /locus_tag="ClothDRAFT_0744" CDS complement(110665..110949) /locus_tag="ClothDRAFT_0744" /inference="protein motif:PFAM:PF02325" /note="PFAM: protein of unknown function YGGT; KEGG: cja:CJA_0090 YGGT family protein" /codon_start=1 /transl_table=11 /product="protein of unknown function YGGT" /protein_id="ZP_05428777.1" /db_xref="GI:256003789" /db_xref="InterPro:IPR003425" /translation="MEGDNLTITALRALGLLLEIIQWAIVIRVLLSWFSIPKNNIFVK FILQLTEPILSPIRSLLENTSFGKNSTVDFSPVIALLILWVVSGFIDIMI" misc_feature complement(110680..110910) /locus_tag="ClothDRAFT_0744" /note="YGGT family; Region: YGGT; cl00508" /db_xref="CDD:153817" gene complement(110969..111436) /locus_tag="ClothDRAFT_0745" CDS complement(110969..111436) /locus_tag="ClothDRAFT_0745" /inference="protein motif:PFAM:PF04472" /note="PFAM: protein of unknown function DUF552; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF552" /protein_id="ZP_05428778.1" /db_xref="GI:256003790" /db_xref="InterPro:IPR007561" /translation="MSTILNKVLNFVGWETEDEEEDVETVEESEDVEEEESKKPQFIQ PLSSRRTQNKVVNIHSASQFKVIVMQPESFNDAKDVCDHLKSKKPVVVNLGSVQKEVA QRIVDFLSGSVYALDGSIQKVSNDIFIVAPHNVDIMGDFKGDITGKAVFPWLK" misc_feature complement(111026..111241) /locus_tag="ClothDRAFT_0745" /note="Protein of unknown function (DUF552); Region: DUF552; cl00775" /db_xref="CDD:153987" gene complement(111522..112226) /locus_tag="ClothDRAFT_0746" CDS complement(111522..112226) /locus_tag="ClothDRAFT_0746" /inference="protein motif:PFAM:PF01168" /note="PFAM: alanine racemase domain protein; KEGG: dal:Dalk_0394 alanine racemase domain protein" /codon_start=1 /transl_table=11 /product="alanine racemase domain protein" /protein_id="ZP_05428779.1" /db_xref="GI:256003791" /db_xref="InterPro:IPR001608" /db_xref="InterPro:IPR011078" /translation="MNGELDYIKRNLYSVMERIEKAAQKSGRSAKDITLVAVTKTVEP ERIMKILDEGVVDLGENRVQELTKKYDILNSRKCKWHLIGHLQTNKVKYIVDKVSLIH SVDRIELAREIQKRAESVGKTVDVLVQVNVSGEKSKFGVSVDDAYGLVREISFMPNIR VKGLMTMAPYAENPESVRYVFSKLRDLSIDIGKEKFDNSNMEILSMGMSNDFEIAIEE GANMVRIGTALFGSRS" misc_feature complement(111534..112205) /locus_tag="ClothDRAFT_0746" /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635" /db_xref="CDD:143483" misc_feature complement(order(111546..111551,111555..111557, 111603..111605,111726..111728,111978..111980, 112044..112046,112107..112109,112113..112115)) /locus_tag="ClothDRAFT_0746" /note="pyridoxal 5'-phosphate (PLP) binding site; other site" /db_xref="CDD:143483" misc_feature complement(112107..112109) /locus_tag="ClothDRAFT_0746" /note="catalytic residue; other site" /db_xref="CDD:143483" gene complement(112263..113531) /locus_tag="ClothDRAFT_0747" CDS complement(112263..113531) /locus_tag="ClothDRAFT_0747" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428780.1" /db_xref="GI:256003792" /translation="MPEENKRKINGKVKLGGLLIALFLLLYIPSFIFWIYGKNIHTDI IRMGELEDYVTTDAYIVRDETVINSPSDGISIRNVEEGEKVGVGDTIATVLNKSSEKL LEDLKTLDLRIIEAKREKTKNDNFFSEDIKKLDQEIQEKLVLVIKKSNKNSISEVKQI KNEIDELIKKKATISGDLSYTDANIKALENEKRILQDSINANKRNIVSNLSGIVSYVI DGYEEILNPEKIPEITPEMLGMIKVVENRKKTDDLSTQYNKPFVKVIGGIDYYIVFVL DREKADDFKVDNYLRVRINDIGRVVDGTIAYKSNEMDGKFVIAVRTDKALSDTAGLRV INVDLIKSRYEGLIVPVKSLVNIDMNTMRAEIALVKARRATFVPVKIVGKNDNFAVID NVEDYKDGGVSLYSSYIINPKNIEEGQVIN" misc_feature complement(112335..112901) /locus_tag="ClothDRAFT_0747" /note="putative membrane fusion protein; Region: TIGR02828" /db_xref="CDD:131875" gene complement(113551..114843) /locus_tag="ClothDRAFT_0748" CDS complement(113551..114843) /locus_tag="ClothDRAFT_0748" /inference="protein motif:PFAM:PF06838" /note="PFAM: Aluminium resistance family protein; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="Aluminium resistance family protein" /protein_id="ZP_05428781.1" /db_xref="GI:256003793" /db_xref="InterPro:IPR000277" /db_xref="InterPro:IPR009651" /translation="MNFESKNYLKNEFGIDDKVLEICESVMSKITPVFDRIDSVREYN QYKVIKAMQNNKLSDSHFVGTTGYGYDDKGRDVLDDVYRDIFKAEDALVRHQIVSGTH ALAVCLYGHLRPKDELLAITGKPYDTLEEVIGLRGEGGGSLKEFGVTYRQLDLLKDGS IDYESIESAINERTAMVLIQRSRGYEWRPALSIDEIEKAINIVKSIKKDIVVLVDNCY GEFVEEREPVEVGADLVAGSLIKNPGGGLAPTGGYVAGRKECVEKAAYRLTTPGLGKH VGASLGHNRLMFQGLFMAPHVVAESLKGAVFCAGVMEALGFETSPKVNDRRGDIIQAV RFNNPESLIAFCQGIQKGSPVDSFVTPEPWDMPGYDCPVIMAAGAFIQGSSIELSADA PIKSPYTAYMQGGLVFEHVKLGIMVAIQKMLEKGIIKI" misc_feature complement(113572..114813) /locus_tag="ClothDRAFT_0748" /note="Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100" /db_xref="CDD:33857" misc_feature complement(<114067..114621) /locus_tag="ClothDRAFT_0748" /note="Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321" /db_xref="CDD:185903" misc_feature complement(order(114121..114123,114130..114132, 114190..114192,114199..114201,114304..114306, 114532..114534,114541..114546)) /locus_tag="ClothDRAFT_0748" /note="pyridoxal 5'-phosphate binding pocket; other site" /db_xref="CDD:99742" misc_feature complement(114121..114123) /locus_tag="ClothDRAFT_0748" /note="catalytic residue; other site" /db_xref="CDD:99742" gene complement(114987..116714) /locus_tag="ClothDRAFT_0749" CDS complement(114987..116714) /locus_tag="ClothDRAFT_0749" /inference="protein motif:PFAM:PF00128" /note="PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein Ig domain protein region domain protein; SMART: alpha amylase catalytic sub domain; KEGG: vfi:VF_2049 maltodextrin glucosidase" /codon_start=1 /transl_table=11 /product="alpha amylase catalytic region" /protein_id="ZP_05428782.1" /db_xref="GI:256003794" /db_xref="InterPro:IPR004185" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR006589" /translation="MKLEAIYHKPYSEFAFPVAPDTLVIRLRTAKNDVNTCILIYHEK YDTSQRGKVKMDKVASDGMFDYYEVELNVGIKRIKYMFYLEDNYSIKWYSSDGFFDYM PQWGHFTYSYICKDDIFHEVEWFRNSTIYQIFPDRFAKFPPDTENSGKRTIHGGNIKG IIDRFDHLVKLGVDVVYLNPIFKSESYHRYDVVDYYEIDPMFGSKEELRELMDLCHKN GIKVIFDGVFNHSGDKFFAFRDVVEKGEKSKYANWYFINSFPVQGYPRPNYECFSFYG GMPKLNTGNPETAKYFLDVVKYWTVEFGVDGWRLDAADEVDRKFWRKLRDMLKDLNKD VVLIGEIFDEASSWLWGDQFDSVINYPLKAMINDLFAYRSIDVETFRNRISGYIMKFN KKVLSSLVNIISTHDTPRFLTLCNGDEKRFELAVVFQFTFPGVPLIYYGDEIGMEGEG DPDCRRPMIWDEAKWNKKTLELYKFLIGLRKRFDALRTGEYGELPVTGCNGILAYRRG RGENGIIVAMNTLDRKENVVVETGDSFDTVKAFESLKDEKRLNVDKKRINICLNPFEW RIYKACGEL" misc_feature complement(116358..116699) /locus_tag="ClothDRAFT_0749" /note="CD and pullulan-degrading enzymes N-terminus domain. Members of this subgroup include: Cyclomaltodextrinase (CDase), maltogenic amylase, and neopullulanase all of which are capable of hydrolyzing all or two of the following three types of substrates:...; Region: CD_pullulan_degrading_enzymes_N_term; cd02857" /db_xref="CDD:30344" misc_feature complement(115158..116675) /locus_tag="ClothDRAFT_0749" /note="maltodextrin glucosidase; Provisional; Region: PRK10785" /db_xref="CDD:182728" misc_feature complement(order(116382..116384,116478..116480, 116484..116486)) /locus_tag="ClothDRAFT_0749" /note="homodimer; other site" /db_xref="CDD:30344" misc_feature complement(115359..116249) /locus_tag="ClothDRAFT_0749" /note="Alpha amylase, catalytic domain; Region: Alpha-amylase; cl07893" /db_xref="CDD:164103" gene complement(116960..119404) /locus_tag="ClothDRAFT_0750" CDS complement(116960..119404) /locus_tag="ClothDRAFT_0750" /inference="protein motif:PFAM:PF00150" /note="PFAM: glycoside hydrolase family 5; lipolytic protein G-D-S-L family; cellulosome protein dockerin type I; KEGG: cja:CJA_2959 cellulase, putative, cel5F" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 5" /protein_id="ZP_05428783.1" /db_xref="GI:256003795" /db_xref="InterPro:IPR001087" /db_xref="InterPro:IPR001547" /db_xref="InterPro:IPR002105" /translation="MKKIVSLVCVLVMLVSILGSFSVVAASPVKGFQVSGTKLLDASG NELVMRGMRDISAIDLVKEIKIGWNLGNTLDAPTETAWGNPRTTKAMIEKVREMGFNA VRVPVTWDTHIGPAPDYKIDEAWLNRVEEVVNYVLDCGMYAIINVHHDNTWIIPTYAN EQRSKEKLVKVWEQIATRFKDYDDHLLFETMNEPREVGSPMEWMGGTYENRDVINRFN LAVVNTIRASGGNNDKRFILVPTNAATGLDVALNDLVIPNNDSRVIVSIHAYSPYFFA MDVNGTSYWGSDYDKASLTSELDAIYNRFVKNGRAVIIGEFGTIDKNNLSSRVAHAEH YAREAVSRGIAVFWWDNGYYNPGDAETYALLNRKTLSWYYPEIVQALMRGAGVEPLVS PTPTPTLMPTPSPTVTANILYGDVNGDGKINSTDCTMLKRYILRGIEEFPSPSGIIAA DVNADLKINSTDLVLMKKYLLRSIDKFPAEDSQTPDEDNPGILYNGRFDFSDPNGPKC AWSGSNVELNFYGTEASVTIKSGGENWFQAIVDGNPLPPFSVNATTSTVKLVSGLAEG AHHLVLWKRTEASLGEVQFLGFDFGSGKLLAAPKPLERKIEFIGDSITCAYGNEGTSK EQSFTPKNENSYMSYAAITARNLNASANMIAWSGIGLTMNYGGAPGPLIMDRYPYTLP YSGVRWDFSKYVPQVVVINLGTNDFSTSFADKTKFVTAYKNLISEVRRNYPDAHIFCC VGPMLWGTGLDLCRSYVTEVVNDCNRSGDLKVYFVEFRQQDGSTGYGEDWHPSIATHQ LMAERLTAEIKNKLGW" sig_peptide complement(119327..119404) /locus_tag="ClothDRAFT_0750" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 at residue 26" misc_feature complement(118328..119191) /locus_tag="ClothDRAFT_0750" /note="Cellulase (glycosyl hydrolase family 5); Region: Cellulase; cl12144" /db_xref="CDD:159804" misc_feature complement(118100..118162) /locus_tag="ClothDRAFT_0750" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature complement(117992..118054) /locus_tag="ClothDRAFT_0750" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature complement(116978..117592) /locus_tag="ClothDRAFT_0750" /note="Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Region: Endoglucanase_E_like; cd01831" /db_xref="CDD:58508" misc_feature complement(order(117032..117034,117041..117043, 117569..117571)) /locus_tag="ClothDRAFT_0750" /note="catalytic triad; other site" /db_xref="CDD:58508" misc_feature complement(order(117032..117034,117038..117040, 117569..117571)) /locus_tag="ClothDRAFT_0750" /note="active site" /db_xref="CDD:58508" misc_feature complement(order(117290..117292,117431..117433, 117569..117571)) /locus_tag="ClothDRAFT_0750" /note="oxyanion hole; other site" /db_xref="CDD:58508" gene complement(119754..>120354) /locus_tag="ClothDRAFT_0751" CDS complement(119754..>120354) /locus_tag="ClothDRAFT_0751" /inference="protein motif:PFAM:PF00404" /note="PFAM: cellulosome protein dockerin type I; KEGG: scl:sce7021 endoglucanase" /codon_start=2 /transl_table=11 /product="cellulosome protein dockerin type I" /protein_id="ZP_05428784.1" /db_xref="GI:256003796" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="PDVVFLWIGGNDLLLSGNVNATGLSNLIDQIFTVKPNVTLFVAD YYPWPEAVKQYNAVIPGIVQQKANAGKKVYFVKLSEIQFDRNTDISWDGLHLSEIGYT KIANIWYKYTIDILKALAGQTQPTPSPSPTPTDSPLVKKGDVNLDGQVNSTDFSLLKR YILKVVDINSINVTNADMNNDGNINSTDISILKRILLRN" misc_feature complement(120018..>120354) /locus_tag="ClothDRAFT_0751" /note="SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from...; Region: XynB_like; cd01833" /db_xref="CDD:58510" misc_feature complement(order(120069..120071,120078..120080, 120321..120323)) /locus_tag="ClothDRAFT_0751" /note="active site" /db_xref="CDD:58510" misc_feature complement(order(120069..120071,120078..120080)) /locus_tag="ClothDRAFT_0751" /note="catalytic triad; other site" /db_xref="CDD:58510" misc_feature complement(119865..119927) /locus_tag="ClothDRAFT_0751" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" ORIGIN 1 tgaaaaaaat aattccgaaa aaaatataga aataattgaa aaaataaaaa aataaagaaa 61 tgattaatga agaatagaag ctttggaaaa taattgacat tataagaata aaataacatt 121 ataaggagaa gaaaatgttg ttacagcaat ttggtgacaa tccggaatta ataatttact 181 ggtttatggt ttttgccttt tccatatcag tccatgagtc ggctcatgct tacgcagcct 241 atcttttggg ggatccgacg gctaaagagc agggaagaat tacaattgac ccattaaagc 301 accttgattt gtttgggaca ttgatgatgt taatcagctt tataggatgg gcaaaacctg 361 tgcctataaa tccgtccaat tttaaaaaca aaaaagcagg caccattttg gtaagtctgg 421 caggtccgct ttccaatttg attttggcgg tgctttttgc cgttcctttt gcttatgtga 481 ctttaaaata ttatcctttg gaaaataatc cgctaaatcc cgcggtaatt gtttataact 541 ttgccctcta tggctttgtt atgaatatat cgcttgcggt gtttaatttt cttccgctgc 601 cgcctcttga cggttcaaaa atatttacgg cagttttgcc ctcaaaatat tactttaaga 661 ttatgcaata tcacaatgta actttcatta tactaatatt actgttgtat accgggtggc 721 tgaacaaaat aataactccg gtaattggcg gagtgcaaag tgccatttta tctgtaattg 781 tacccataat aaaactcatt gtataaaaat atgattagac tttaacagaa aaaaaagata 841 taattaatta ttgtagaatc aaatgataag atttattata cgggagtgtg aagtcttagt 901 gaagaaaggt actattttga gcggcatgag acctaccgga gctttgcatc ttggcaatta 961 tttcggagct ctggaaaact gggtaaaact tcaggatgaa tacgagtgtt atttttttgt 1021 ggctgattgg catgccctta caacaggata tgaagataca tctcaaatca aaaataatat 1081 aaatgacctt gttatagatt ggctaagtgc aggacttgac cctgaaaaat gcgtcatatt 1141 tttgcagtca agtataaaag aacatgcaga gcttcatctg ttgttttcca tgacaacgcc 1201 tctttcctgg ctgcttcgct gtccgacata caaggatcag attaatcaat tgaaggacaa 1261 gaatattacg acctacggat ttttaggata tccgtgtctt caggcagccg acatattaat 1321 ttacaaagcc ggttttgtac ctgtgggaga agaccagctt ccgcaccttg agttgacgag 1381 ggaaattgca agaagattta attatttgtt tggcgaggta ttccctgagc cgcaggcaat 1441 tttgaccaag gcaaaagtat tgcccggaac cgacggcaga aagatgagca aaagctatgg 1501 caataccata gctctgtccg acagtcccga tacaatcaga aagaaagtca gctcaatgat 1561 aaccgaccct gcaagaatca gaaaggacga tcccggtcat cccgaggtgt gtacggtatt 1621 ttccttccac aaagtattta atgaaaatga agtgcctgaa attgagcagc actgcagagg 1681 cggaaaaatt gggtgtgtgc aatgtaaaaa gaaccttgct gacaaaatgg tggagcattt 1741 ggagcccata tatgaaaaaa ggcaaaagat agttgaaaat ccgtccatag tcaaagaaat 1801 tctcgcagac ggaaatgaaa aagccagaaa ggttgcgcaa aagactcttg aagaagtacg 1861 aaaagccatg aaaatagatt ttatttagcc tttttcctgc ggggtcttaa aaggtggtga 1921 acttttttgg aaagtgtgtt gtcaaaagca tgcactataa aaatacaaaa ctttgaagga 1981 ccgtttgacc tgctgtttca ccttatcgaa aagaatcaga taaatatcta tgacatacct 2041 atacacgaaa taacggacca atacatggat tacctttttg caatgcagga gcttgatttg 2101 gagatagcca gtgaatttct ggtaatggca gcaacacttc ttcacataaa atcgaagctc 2161 ctacttccaa gtcctaaacg ggaaaaagag gaggacgagc ctgaccccag ggaagagctg 2221 gttttaaagc ttattgaata caaaaaatac aagagattta ctgaaatttt gaaaacaaga 2281 gaaaaagaat gcgagaaata tttttacaga ggtcctgagg atattgacat caaatgtgag 2341 gatgaacctt tggaattgtc ttatgatgag ctaaagaggg tctacgttga gttgatagaa 2401 agaaatgaaa gaaaaatgaa caaaaatacc ggaaaaatga cccagatagt gcagcatgaa 2461 aaagtcacac tgcgcagtaa aatcagagat atcatcagga ctcttcttaa aaagccgatt 2521 ttcaagtttt cggagctttt ttctccaaaa accagatcca gacttgaaat tgttacaggc 2581 tttctcgcga tacttgagct ggcaaaactg aaaaaaataa ccctgataca gccaaaaccg 2641 tttgcggata ttactgtctg caaatgcgaa gataccaatc ttgaggatat tgacgatgaa 2701 aatgtggcag cggaaaactg acagcagtgg agtgatacaa atggatctaa agaaactcga 2761 aggaatattc gaaggtatgc tttttgcttc aggcgacaaa gtttcgattg aaaaattaag 2821 cagcataaca ggcattgaca aaaagacagt aaagcttgtt ataaacaata tgatagtaaa 2881 gtacaacaat gatccctccc ggggaattac cataagggaa ataaacaatg gttatcagct 2941 ttgttcaaag ccggaatatt atgattatat aaaacagctt tttgaaccta aacaacgcag 3001 tggtctgtcc caggcagccc ttgaaacctt ggcaattatt gcctataaca gacctataac 3061 caaagcaaaa attgagcaaa taagaggtgt aaactctgac agtgcgatta caaaacttct 3121 tgaaaaaaat ttaatcagag aagcaggaag gctggatgcc cccggaaaac cggtattgta 3181 tgaaaccact gatgaatttt tcaggagttt tggttttaag tccgatgcgg atctacctat 3241 attcgaacta aatgatatac atgagactgt tgaaatcaat caaaacagtg aacaggaaaa 3301 agcagataca gaattggaga agcaggaaaa ggcataaaac gaacagcaat aatctagggt 3361 ggtttaaatg agtgaatacg ataggaaaac tgaccctcaa gggttttaca acatatttac 3421 cgttcaaccg tgggtgagat tttgggccag agttattgac acttttatta ttgacaccat 3481 tgtgagaata actcagttgc tttttttccc gggcagtacg ttcgagcctg tattgcttac 3541 tgtaggaaca tattttattt gggctcttgc cgaggcaaaa ttaatttcaa cctggggaac 3601 cactcccggg aagtggctgc tgaaaataaa ggtgaggtcc aataattccc aaatacttga 3661 ttttaaaaca gcccttaaaa gaagcatact tgtttggatg ctaggtatgg gctttggaat 3721 tttcacaact atatcctata tttttggcta ttatgagtta accaggaaag gcattacgcc 3781 ctgggacaga atcagtgaat gcacggtaca atacgaaaaa ataagtgaaa acagacgaat 3841 agcagtggtt ttaacagtca ttggactcag tgtcatgtat tttgcactga tttttgtgaa 3901 tgcccttttg tattcaataa aagctcatgg gctgtaaaat ttgtaaaagc aaaactttat 3961 aatttaattg ctgcggaaaa atacacaatt tatgtgtatt ttttgttttt ataggcaaaa 4021 ataagtaaat gaggtgcggc aatgttttat agaatcattt ttgtattgat tattcttata 4081 ctaataatta tggtgttttt tgtaaaaatc aaaattgtga ttgaatacag aaaaggcggg 4141 caaaatgacc actttgaagt agcttttttt gtgttaaaaa aaaggtttgg atacaaaaaa 4201 acaaatcaac tgaagaaaag gacggaatac ttaccgatta taaaaaactt ataaaaaata 4261 tagaaaaaag tagaaatttt tatcaaaaaa taaagaaata ataatgaaaa ttctaaacta 4321 tattaaatgc cgaatatatg ttgagagact ggaatttaag gcagtaatcg gaacaggaga 4381 tgcgtcttcc gccgctatac tggcgggtgt tgcatggagc cttgcgggaa ttttgttttc 4441 catacttcac agtttcacaa atgtgaaaaa taaaaaggtg gaaataaggc cggactttac 4501 aggaaagaag tttaatgttg aactgtattg catatttaag gttaaaattg tttatattat 4561 tgttataggt ttgatgatac tcaagcactt aataaaagca aaagtcggtt ttacaaatgt 4621 aaaaagaagt attgcagtgt acaaatagaa taaagtcttc gtaaaaataa tataccaggt 4681 ggtgacaaat aatggcagag catcctattc aaggtctaat ggaaacggca atggaaagca 4741 ttaaagaaat ggttgatgta aataccatag taggagatgc agttcaggct ccggacggaa 4801 cggtaattat acctatttca aaagtaacct ttggttttgc ggcaggcggc ggagaatttg 4861 cttcatgctg cagtgtggac gaaaaaggcg aagacagctc agacgacagc agcaaacccg 4921 aaatcaaatt tccctttgca gggggtagcg gcgccggagt gagtataaac ccggtggcat 4981 tcatggtggt aggccaggga cagattaaac tgctgcctgt aaatatcaat tcctctttgg 5041 agaagatact ggatttgatt ccggagatta ttgaaaagac gaaggattct gtaaagaaaa 5101 atctcaaagt gaaaaaagaa ataaagcccg gtaacggtga gtcatgtgct aaaagttcaa 5161 aagaagatga gaatgaataa gtgggaaaaa cccacttttt ctttataaat tttttttata 5221 aaaaaatata aataaattaa tttgaataat ttaaaaaccc gtaaatttat gatatattaa 5281 tatattgctg atgaatttct cataatatca caatactttt gataaaaatt atcttaggta 5341 aaaacaataa aaatttatga aggatcgggt tgtctttatg aaagagatga ggcttcaaaa 5401 gtaccttgct gaatgcggtg ttgcatcaag aagaaaggcg gaagagctga taagccaggg 5461 cagagtcaag gttaatggtg aaacggtcac gcaaatgggg aaaaaggttt cccaaaacga 5521 tgtggtggaa gttgatggaa agctggtcaa aatggagaaa agaaaggttt atatagcatt 5581 aaataaaccg gtggggtaca taagctcggt aaaagatcag tttggcagaa aaacggtgat 5641 ggatctggtc aaggatataa aggaaaggat ttttccggtg ggaagacttg attatgacac 5701 ctccggtctt ttgctgctta ccaatgacgg agattttgcc tacaggctta ctcatcctaa 5761 gcatgagata aaaaaggtct atgaggctga tttactgggt gtaccttcaa aggacgacat 5821 aatgcgtttt aaaaatgggt tatggattga tgattatttt acaagtccgg ccgattttga 5881 aattttgaaa agtgacggta aaacgacgaa agttagaata accatacacg aaggaaagaa 5941 ccgtcaggta aggaaaatgt gtaataagat aggctgcccg gtaataaggc tcaaaagaat 6001 ctccatcggt gaggtatccc tgggtgattt aaaggaaggc tcctggagga acttgactga 6061 gagggagata aactcttttt tggataatca aaagtaagta aagtacaaat ttggtgaaaa 6121 agtaatctgt tctgataaag ttttccgcaa actaaaagtt acagttaata tgtatgctca 6181 ttattattgc taaacgaaaa aatacaagac gattttaata atcttttgac aaaacattat 6241 ttccaattta aaatattaat ggctgtaaaa tggacagcaa agtacactta tttaaaaata 6301 tatagaacag gagttgaagc aaatggaact ttggtttaca gagtatcaga cccctacatt 6361 gggaatcact tgcaagacaa aaaagacttt gcacagtgaa aaaacagagt atcaggaact 6421 ggcagttata gaaacggaac agtttggcag aatgctcctt ttagacggaa taattcagac 6481 tacggttgcg gacgaatttg tctatcatga aatgatagcc catgttccgc tgtttactca 6541 taaaaatccg aaaaaagcgc tggttgtcgg aggtggagac ggaggctcaa taagagaaat 6601 agtaaagcat ccatccattg aaaaggcagt tttatgcgaa atagacaggc gtgttattga 6661 ggtgtcgaaa gagtatcttc cggaaatcag ctgcgctttg gataatgaaa aagttgaggt 6721 agttgtaggc gacggtatca aatatgtaaa agaacataaa aatgaatttg atgttataat 6781 aattgattcc acagacccga taggacctgc tgaaggcctg tttgccattg atttttacag 6841 ggctgtatac gattgtttga aggaagacgg tatatttgtt gcacaaaccg aatctccttt 6901 catcgataaa gagcttataa caaggataat tagagatgtg aaatcattgt tcccgataac 6961 aaggctttac acatgtacaa ttcctacata tcctacagga tattggtgct ttaccatggg 7021 atcaaagaag tatgatcctt tagaaaccga catagactcc ataccggata tcgatacgaa 7081 atattactgt ccgcagattc acagagctgc attcatactg ccgaagtttg caaaagaatt 7141 aataaaataa tttttaattt gaatttgatg aggtactgac atgagtttaa gaaacgggaa 7201 ttctacattg ccgaccaaat ttatggcaag cattgacagc tacgatgatg catccatagt 7261 catggccggt gttccaatgg actttacctg cagcttcaga ccgggaacaa ggtttggacc 7321 gcagaaaatc agggaagtat ccataggcat tgaagaatac agcgtataca tggaccggga 7381 tttgacccag tgttctttct ttgatgccgg tgacttggat cttcccttcg gtgacgtgga 7441 taaaagcttg aaacttatcg gggacgtggc agaagagata ctcagcgaca ataaatttcc 7501 gctctttatc ggtggagagc atcttatcag cgtaccggta ataaaaaagg tgtatgaaaa 7561 atacggacct gaactgatag tggtgcagtt tgacgcccat gcagacctaa gggaaggata 7621 tctgggatgc ccaaactctc atgcttcggc tgtaagacgc ttgattgact ttatgccggg 7681 aaaaaatatt tatcagttcg gtataaggtc cggaacgaaa gacgagtttg aatatgcaaa 7741 aaaacatacc aacatgtata ctatcgacgt ttttgagccg ttaagccgtg tcttagacga 7801 tatcaaggac aagcccatat acataaccct tgacatcgac gtggtagacc ctgcatacgc 7861 gaacggtact ggtacaccgg agcccggcgg gatcagctcc agggaacttt tggattcaat 7921 acatctgttc aagggagcaa atcttgtcgg atttgacatt gtggaagtat caccccacta 7981 tgatcaatct gaccggacgg cgctccttgc ggcaaaaatt atcagagaaa tcattatgat 8041 ggtcggatga ggcggattat gcagactatt aagaattctc tggggcagtc ccacgactac 8101 attaaaatgt ttgtcaaaga aggagacaca gtggtggatg cgacctgcgg aaacggaaac 8161 gatacagctt tcctcgcaag tctggtcggt gaaaacggca gagttttcgg ctttgacata 8221 caggataagg caatagccaa tacaacaaag aaacttacgg atttaaacct tattgacagg 8281 gtaacactta taaaagacgg acaccagaac atggacaagt atattgattg tcctgtaaag 8341 gcggttatgt ttaatttggg ctaccttccg tcaggagacc acagcatctc caccaggccc 8401 gaaacaacca tacaggctct ttcaaaggca atggagcttc ttgttacagg aggcattata 8461 accgttgtca tttattacgg aggagatacc ggttttgaag aaaaggaaaa agtcctggaa 8521 tttttaaaag gtgtggatca aaagaaattt atcgttcagc gcaccgattt tataaatcag 8581 gcgaactgtc ctccaatatt ggtttgcatt gaaaagatat cataagaaaa tacaaatata 8641 aaagtgtaat tgattgatat ccaataaatg aaatcaaaat acaggcaaat atttaagggg 8701 cttgttgccc cttaaattgc ttttgatgca aacactataa aaatcaacag aaaaatccca 8761 aatatggata ttgcatatac ggaatacttc agcctgttaa acattttcca ctcctgggca 8821 aggtgttttt ttgggtttga agatattcaa tcagttcgaa taaaaggtta tgattggcat 8881 catctatatc aacaagctgc actccatagt tgtaaccacc ttttttatcg gcgattcttc 8941 tgataacttt cccggtaaaa gatatcgtta tcttaggtgt tacaaacata tcaataccta 9001 tgttttttcc ttcctcaaac aaatcatctg agtgtatcag gcctcctcca aggcttatat 9061 ccgaaatgga cgcaatatat gatacgtttt cttcgtatct tatccggcag gggtagttta 9121 cacgaaacct ttcgtatttt ctttgattat tgtaactcaa tactttgttt atctgaattg 9181 taatggcttg ctttcttatg gagattactt ttttagaaac gcttccgcta aacagtgtct 9241 caatattttc atcaagggat tttacaacga ttttacttcc ttcgttaaaa tagcttttaa 9301 aatattttgc agaaaggaat atctcggcaa tatttttttc catgttaata tacgttatta 9361 tgccgtgaac ccatttttca tcgttattta ttgaaactct gcagaaaatt ggagaatcat 9421 tttgaggaag caaatcgttt aacaatttaa ccaccctgcc ttttacaatt attcatatca 9481 taaattttat cgtcaaaaac gttaaaattc tagacaaaaa aaccgacata tattttgttg 9541 attttataaa gatttatata aaagcattaa aaggctgtgg tccttttttt atttttacat 9601 cataaacatt tggggaaaat attgcaatat gaaataaagt aggatataat tgataataat 9661 tataaccagg taataatatc atataataaa taaaaagtaa cagatataaa taaaagttgc 9721 aattgtatta ctcaaaatgt atacgactgc atttggaggc tactggatac aaaaccaata 9781 aataaatgac aagaggtggg aaactgatgg acaaagtaga caagatcggc cttctccgtg 9841 aaaaactggc ccaggttgaa cagggcggag gagctgaaaa aatcgcaaaa cagcatgatg 9901 ccggaaaaat gacagcaaga gaaagaatcc aggctttatt tgatgaaaac agctttgttg 9961 agatcgacac atttgttgag acaagaagca ttgacttcga tatgcaaaaa aagaaagtcc 10021 cgggagacgg tgttgtaaca gggtatggtt ccatagacgg acgtctggtc tttgttgcgg 10081 cgcaggactt tactgtaatc ggtgggtctt tgggtgaaat gcatgccgca aaaatcacca 10141 aagtaatgga catggcaatg aaaatgggcg caccgtttat aagcattaat gattccggcg 10201 gtgcaagaat tgaagaagga attgacgcac tcaagggatt tggagatatc ttctacagaa 10261 atactttggc ttcaggtgta attccccaga tttcagttat catgggacca tgcgcaggcg 10321 gagcggtata ttctcctgca ataaccgact ttatatttat ggttgacaaa accagtcaga 10381 tgtttataac gggaccccag gtaattaagt ccgtaaccgg agaagacgtg acttttgaaa 10441 aacttggcgg tgcggaaacc cacaactcca taagcggtgt tgctcacttc agaagttcaa 10501 gtgaaaaaga atgtatagag caaatcaaaa agcttattag ttatcttcct gataacaatc 10561 tttccgatgt tccgattgtt ccaactcagg atgacataaa cagaattact gacaacctgg 10621 tcgatatcat tccgcaggac tccaacaagc cttatgacat gatggaaata atcacttccg 10681 tagttgacaa cggtgacttt tttgaaattc aaaaagactt tgcaaaaaac attataatag 10741 gtttcggcag aatgaacggc ggaaccgtcg gtatagtggc aaatcagcca aaagttgccg 10801 caggggtttt ggatgtgaac tcctctgaca aagccgcaag gtttgttcgt ttctgtgatg 10861 cgttcaacat tccaattata acctttaccg atgtaccggg gtatctgccc ggagtaggcc 10921 aggagcacag cggagtaata agacacggtg caaagcttct ttatgctttc tctgaagcca 10981 ccgttccaaa aatcaatgtt attgtcagaa aagcttacgg cggtgcatat attgccatga 11041 acagcaagca ccttggagcg gacatggtat ttgcatggcc ttcggcggaa attgcagtta 11101 tgggaccgga aggtgcggca aacatcattt tcaagaaaga tatagctgct gccgatgacc 11161 caatggaaac aagaaagagg ctcattgaag aatatcgtga aaaattctcc aatccgtatg 11221 ttgcagcttc aaggggttat gttgatgatg taattgatcc ggcaacaaca aggataagac 11281 tgattagtgc ccttgaaatg cttgcaagta agagagaaaa cagacctgcc aaaaagcatg 11341 gaaatattcc attataagta tggatgtaga gtagggagga ttttatgaaa gagcaaataa 11401 atgaagaaat tattctggca atatcagcgg ccattgctgc tttggaaaca agacccggat 11461 acaagcttgt agtaagatca tttaaaagaa taccccaaac ttctcctgta tggtccgcta 11521 caggaaaaat cgagagaatc agaagaagta tgtaaaatct aatttataag gaggattaaa 11581 catgaaaaag tttttgataa aggtaaacgg aaatcaatat gaggttgaag ttgaagaaat 11641 cagagacggt gcttcagcac cacaggttac tctcagcaca ccttcggctg cacctgcgcc 11701 ttcaccggca ccggctcagg aaacgaaagc agctgcacca aagaaagaca gcacagtacc 11761 ggcaggtgct acggcaatta aagctccgat gccgggtacc atactcgaca ttcgtgtaaa 11821 tcaaggggat acggtaaaga aaggccaagt tcttttaatt cttgaagcaa tgaagatgga 11881 aaatgaaata gttgctccaa atgacggtac agttgcatca attaatgttt caaagggtgc 11941 atctgtaaac gtcggagagg ttcttgtctc attaaaatag tttgatagaa atgtttttgt 12001 gacgcaattt ggcaaacagc aacgataaaa acaacaatga ttgaaaaacc ttaagttgtg 12061 gtagatataa cgtaatggat taaaccactt ttgtggttgt tcccaaaaag gaggtaagaa 12121 caaatggcta aggtaaaaat taccgaaacg gcgctgaggg atgcccatca atctctcatt 12181 gcaacaagaa tgagaataga agagatgctt cctatcatag ataaactgga cgagatcggt 12241 tatcattctt tggaggtatg gggcggtgca acctttgatg cctgcctgag atttttgaat 12301 gaagacccgt gggaaaggct tagaattata aaaagccact gcaagaaaac tccccttcaa 12361 atgcttttaa gaggccagaa tcttttgggt tacaagcatt atgccgatga cgttgtggag 12421 tactttgtac aaaagagcgt tgcaaacggt ataaacataa taagaatttt cgacgccttg 12481 aatgacacca gaaatataga aactgcaatc aaagcctgca aaaaagaagg cggtcatgct 12541 cagggaacgg tatgttatac aataagtccc gttcacaatc ttgaactttt tgtcaaagat 12601 gcaaagactc ttgtggaaat gggagctgac tccatatgcg taaaggatat ggcaggactt 12661 ctgcttccat atgttgcata tgaccttatc aaagcattaa aagaaaacgt aaaagtgccg 12721 attcaacttc atacccacta tacgagcggt gttgcttcaa tgacatatct gaaggcaatt 12781 gaggcagggt gcgatgttgt ggactgcgct atctcaccaa tgtcaatggg aacatcccag 12841 cctccgacag aacctcttgt ggcaacctta aaaggcacgc cgtacgatac cggacttgac 12901 ctggataaat taagtgaaat cgcagactac ttcagacctc tcaaagaaaa gtatatttca 12961 gaaggacttc ttgatgtaaa ggttatggga gttgacgtaa acactctcaa ataccaggta 13021 cccggtggaa tgctttcaaa cctggtgtct cagttaaagc agtccaatgc ggttgataaa 13081 ttcgaagagg ttctgaaaga agtgccaaga gtaagagaag acttcggata tcctccgttg 13141 gttacaccta caagccagat tgtaggtact caggcagttt taaatgtggt aacgggtgaa 13201 agatacaaaa tggttccaaa agaatccaag gcactgatca agggtgaata cggcagaaca 13261 ccggctccgg tcaaccctga agttcagaag aagattttaa aagatgaaga gccgattaca 13321 gttagacctg ctgatttgat agagcccgag cttgacaaga tcagaaatga aatgaaagaa 13381 tacctggaac aagacgagga cgttttgtcc tatgcactgt tcccgcaggt ggcagagaag 13441 ttcttccaat acaggaaagc tcaaaaatat aagatagaac cggacatggt cgattacgaa 13501 aacagggttc atccggttta aagtagagta ttgagccatt tgtctcagaa atacaataaa 13561 agcttgaatt tatgattcaa aataaaaaac tcaggacctg acatggtgcc tgagtttttt 13621 gctgtattca aattcattaa aactaatact tttttttatt aaataacaat agacaaaaat 13681 aaattgaata tgataaaata tggattgaaa atcaattatt aaaaataaaa tagttatatg 13741 taaaaacaat atatttttct atgaggtatt cgttatgaga aaaatatgtt gcttgttgtt 13801 tgctgtattc attctttgta tttcagcgtc atgctatcaa agaaaagaaa cacgaataag 13861 ccaacctgtt ataatgcctg ccatccaaag ccctgaagat attgatgatt acatagggga 13921 aaagggatat gagattttag agtctaaagg aaagactgag gaatacacat tagacaaaaa 13981 aagggtgtat aacaattggc aaatttgggc tgttcagtac ccggagccgg accattatct 14041 cgggaaggaa atatcaattt attcgtatat aataagaaat catcctttag atgacaaatc 14101 ccccaataaa aaaacctatt tatccgtaat gatttgtgaa aatacaatca ttggcggata 14161 ttcaagtccg tattacgaag aaaaagacat ttcgctggtg ccgataggag gagtttattc 14221 actggaaggc aagaattttg aagaaattaa aaatattaat tttgataggt ggagaaaaag 14281 atttattaaa aaatatgaat aatgtgaata taaaaaataa tatcggaaaa atgaataaaa 14341 accttgaaaa caaaaattat ttttggtatt atgtttgaag taaatctttt attttacggc 14401 tcatcgggag gacataaaaa tggatcaaaa atcttttgaa cttctcgcaa acatgtacca 14461 cgaaataaaa gaacaacttt ccgaaattag caagaagctg gataaaaagg cagacaaaag 14521 tgacattgtc cggctggaaa atgaactcac ccccaaaatt caagctttgt ttgatggata 14581 caagcagcat actgacattt tggaacgcat tgaaaatgaa gttatgaagc aggatgaaat 14641 catcatgaga cgtgttaaat aacataccaa tcatcggcag caaaatatta aatcatggca 14701 gcaagtgtca gccaacccgg catcaacatt cgtggcattt actgtgaaga tagacaaaat 14761 gctctttgtt acttacaaat cgcaaaatct ttattctact gcctttccta atatgttttc 14821 cgcattttag gcaaaatata tgagaatact tcatcacatc gtcatgaacc tctcgttgaa 14881 ttccttcata ctttgcccag ctctgccatc cggttttgca caaagatatc ctgttgttgt 14941 agtctgcaaa aacccagcgc aaaagcttgt gaaaatgaaa ggggtatttt gtgtatttta 15001 gataggcttc cggtacccca agtctcattg tgtagagcat gaaattctgc tctacaattt 15061 cctgaatacg gccgcttata tgggttctgt accagcagta gccgttggcg tcaagccagt 15121 gccttaattt ctcaaacatg tatccgcggc atatttcaac cgtttcgctt ttatgtacgt 15181 tcaatgcttt aaaagcttct tcaactatat ctaccaccgc gtcaagataa agttttttct 15241 taaagttttc cttgttataa agttcaacag ggataatttc aaaaaaatat tcattcgttt 15301 ccggtctgta tactccaata catgttcccc cgacaaagct tccactgcct gcatcgtcaa 15361 tttgtatcat ccgcgccacc ccgatgtagt atttgctaat atttaaaaat tataactttg 15421 ttgtaatgtt caatattctc atgtctgtgt tacagataaa atttgccgta taggttctga 15481 atgcaggaac ttgattttta tactgcaaaa ttgtatatta aaataaaaaa gcatttacgg 15541 aggataaata tggatcttga tgataagttg gagcttaaag ctacagtaga agtatctgca 15601 aatttggaat tatataaagt agttgatttt ctcaacaaaa atcttaaaga taaaaaactg 15661 attttcggtc tatccaaaaa agacaacaaa atgataattt caatttatga aacgtaatat 15721 cagacatgag gggatatggc aatggatatg gataaagagc aggatttgtt gaaaagaatt 15781 caagccggta tgccgggttt tagcaaaggt cagaagctta tagcaaattt cattataaat 15841 cattacgaca aagcagctta catgactgcg gccaaactgg gagaagaagt gggagtaagc 15901 gagtcaacgg ttgtaaggtt tgccaacgaa ataggatttg acggttatcc aaaactacaa 15961 aaagttttaa gagaaatgaa taagagcaag cttactgccg ttcagcgtat tgaagtaact 16021 tccagtagaa ttaacgaggg aaacatatta aaaagcgttc ttcaatcaga catggaaaaa 16081 ataaaggcaa ctttggaaga aattgaccag gaaagcttta ataatattgt taaaagtatt 16141 ttaaacgcca gaaagatata cattctcggg gtaaggagtt ctgctcctct tgcaagtttt 16201 ctgggctttt acttcaacct gatatttgac aacgtaaggc ttgtacacac tacaagtgtc 16261 agtgaaatgt ttgagcagat aattcatgct tcccgcggag atgtagttat aggaataagc 16321 ttcccgaggt attccaaaag aacaataaac gccatgcgtt ttgcccaaaa ccagggagcc 16381 accgttgttg caatcacgga cagcctttat tctcctttgg caaaaaacgc ggatcatgtt 16441 attacagcaa gaagcgacat ggcttctttt gttgactcac tggttgcacc tttgagtgta 16501 ataaatgcat tgattgtggc cattggaatg agcagaaaac cgcatgtaca agaaaccttc 16561 gaacgtcttg agaagatatg ggacgagtac aaagtgtatg aaaaacaaga ttacgattcc 16621 aattacggag aggaagatta agaaagtgac agtattgtat ctggttcgcc acggccaaac 16681 cgactggaac aaggaaaatc gatgtcaggg acgtatagac acggaactta acagtgaagg 16741 aattcttcag gctgaagcca tagctcaaag acttgccggt gaaaacatag acgttattta 16801 ttccagtgcc ttaaaaagag cctacaccac cgctgagatt ataaaccgca agctgtccag 16861 agagcttgtc agaaatgagg cattaaacga aattgatttt ggcgaatggg aaggcctgac 16921 gtttgaagaa atgcgaaagc gccctgatta tagttatgag cagtggaggc tgatgcccca 16981 tcttgtcaca tttcccggag gagagaaaag ccttaaaaac gtccaggaca gggccatgaa 17041 atttgttaat gaaataattg aaaagcataa tggaaataat attttaatag tatcccatgg 17101 cggtgttata aaattaatta tattgggcat gctgggtata ggccttgagg cttataacaa 17161 atttttcatc gcaaatgcat ccttgagtat tgttgttatt gaaagtgaca gagcattctt 17221 aagaacgctt aatgacacat gccatattaa aaatttgatt accgctaaat cttgaaataa 17281 cggagtaata ctaaaaaatg ggaaagaaag ttgttgtaat aggagcggga cccggcggta 17341 tcatggccgc cggcaaagcc gcggaacgtg gacataacgt cacacttttt gagaaaaatg 17401 acagaatcgg aaagaaaatt ctcatatcgg gcaagggaag gtgcaatatc accaataata 17461 ccgatattga aggattaatt gagaatattc ctggaaacgg gaatttttta tattctgcct 17521 tctacacctt ttcaaaccat gatttgattg agttttttga acaatacggt ttaaaaacca 17581 aggttgaaag gggaggcaga gtatttcccg tttcagatga tgcaaaagat gttaataatg 17641 cattgttaaa gtttttgaac aaggcaaagg ttaatctcag actaaattcg cctgttcagg 17701 agataaaagc aaagaacaat actgtgacgg gtgtggtttt aaaagacggc actgaagttc 17761 cctgtgatgc tgtagtgctt gccacagggg gtgcttcata tcccggtacc ggctctaccg 17821 gagacggcta tgttatggca aaaaaacttg gacacaccat tgtagaccta aagccctcct 17881 tagttcccct tcttgcagag gaagagtggg taaaggagct tcagggtctt tctttaaaaa 17941 atgtttctat aaccatatta agcaaagcag gcaaaaaaat ttataccgat ttcggcgaaa 18001 tgctttttac acattttgga gtctcgggac cgattatttt aagtgcaagc cggcacattc 18061 ttgactatga ttacaaaaat gtcaaactgg ttattgattt aaagcctgcc ctttcagagg 18121 aaaaacttga tgaaagaata ctgagggact ttgaaaagta ttcaagaaaa cagtataaaa 18181 actcactgga tgaccttctt cccaaaaaaa tgattccggt gatagtaaag ctttcaggta 18241 ttgaaccgga aaagtttgta aaccagataa aaaaagaaga aagaagggct ttagtgcggc 18301 ttctcaaaaa tcttaccctc aacataaacg gttcaaggcc tattaaagaa gccattgtta 18361 cggccggagg agtttcaacc gacgaaatca acccttcaac aatggaatca aaacttgtaa 18421 aaggcctgta ctttgccgga gaaattattg acgtggatgg ttatacgggc ggctttaacc 18481 ttaccattgc attttccaca ggttatcttg caggtgtcag ctgctgattt tgcgtaaagc 18541 tgcaatcaag gtgtgtttta agtgtatttt ttaatggatt tgagcatatt attctatagt 18601 aaaatccatt aaaaaaatac ggagtgattg ggatgaaagt gattgttttc agagcaaaca 18661 cgaaaaagaa caaaaagact catgcaaaag ccgtaaatcc cagattcgga tttgaaagat 18721 ttttgttctt ttcgtttata attttgtttt cggctctggt tttggtacag gcagctttaa 18781 tgaatcctgc aactcgaacc tttctggtaa atgataacgg gcttgagggt tctcctttgc 18841 agtttgaaga atacctttac agtgaagggg agatttccgt agctttgtgc agtgccgacg 18901 ttgacgaaaa cctgaagctt cttgtaaacg gagaggaagt tgctgtattt tcacaaaacg 18961 tgataaatct caaggtaaaa gaaggagacg ttgtttccgt ggacggaagc tctacagaag 19021 aagcggaagt tgcaatagtt tacgcaacag acaacataaa gctggataac ataggggaga 19081 gaataaaagt aaattccgaa gtaaagcata ttgcacgaat aataattgaa taattcttca 19141 atttttttta ttgtctaaat ttcattatta aagtataata taatagtgct tgttctgatg 19201 agagtttgta aaagaccaaa aataaaggct tatataatta ttacattaat gggtggcttg 19261 agaggtaaat atagcaaacg atactattga cgcaggaaaa tatggaagca aggagattgc 19321 agctgcagca attgaaatag ctttaacaaa agacagagtt tcggaaaaac ggttgcagtc 19381 tgagtacggc aaaatcggca tacgcactgc tgcggtggac tacggaggag agtttatcac 19441 ctctgttatg aaaataatag aaagggctgt tgtatcgtct aaaagagaag gtgtcattac 19501 tgacaatcat gtggaagagg gagccgttgc cggtgccaca agggaggcat tgtcacaaat 19561 tatgcccaaa gcactgggac ttaatgtcgg cggtaaaatt ggtgttgcac gatacaaaga 19621 tcatatttcc gtagcagtct tttttggaat aggcctgctt catttgaatg aagttgccat 19681 aggtttgggc cacagggttg tttagatttg aaaattataa gccgtatgat tgccaaaaat 19741 gttggcaggc aggatggtag aacggtatac aggaggattt gattataatg gtatgggcta 19801 tcagaggtgc gaccactgtt tcagacaaca ctgcggatga aatagtggct gaaactcaaa 19861 aactgcttaa agaaatggcc gaaaaaaacg gacttgagga agatgacata ataagtatta 19921 tttttaccgt tacaaaagat ttggatgctg cattcccggc aattgcagca agaaatatgg 19981 gatggacaag tacggcactt atgtgcatga acgaaataga tgttccggga agcctggaga 20041 aatgcatcag agtaatgatg cacgtaaaca ccgataaaga caagaaagat ataaaacatg 20101 tataccttaa cggtgcaaag gtgttaaggc cggatttgac ttaaaaattg agatactttg 20161 aaaattgggg taaaaaattg aaataaaatt tgttttcttt gggagacaaa catgaacgga 20221 aaagccagaa tttcaattgc cattgacgga cctgccgggg caggaaagag tacaattgca 20281 aagattattt cgaaaacttt gaatatattg tatttagata ccggggcaat gtacagggca 20341 gttgctttaa aagccataag agaaagcgtt gacacgttga accgtgagca aatgtcaaag 20401 cttgttgaaa acattgacat aaaaattgcc cattctgaag atattcagcg cattttctta 20461 gacggtgagg atgtaaccga ctttataagg actcccgagg tctctatcgg tgcatccaat 20521 gtggctaccg ttccggcagt aaggctcaaa atggttgagc ttcaacggga aatagccaaa 20581 aagaacagtg tcgtgatgga cggtagagac ataggtacat acgtattgcc cgatgcaacg 20641 ctcaagttct ttcttactgc ttctgttgaa gccagggcaa taagaagata taatgagctt 20701 ttgtccaaag gaataactca gataactttg gaagatgtaa aaaaagatat agaatacagg 20761 gataaaaacg acagcaacag ggaatttgct cctttgtcaa aagctcctga tgctattgaa 20821 attgatacca ccgatttgac tatagaacaa gttgtaaata aaattatgga gtatgcaaag 20881 gactatgtat gctagtttga agaatatata ctatggtttt ctgagggcaa ttattactac 20941 gttttttgac ttgttttaca gggtgagtat tatcggtata gaaaacgttc cggtagaagg 21001 tcctgtactt ttgtgtgcaa atcacattgc tgaaatggat atgtttttta taggatacag 21061 gctgaaaaga ctggttagat acatggccaa ggaagaactc ttcagaattc ccttagtatc 21121 ttcatttata aaaagccttg gcgcttttcc tgtaaagagg ggaaaaggag atgtcggagc 21181 aatcaaaacc gctttgaaac tccttgagga aggtcatatt gtcggtattt ttcccgaggg 21241 cacaaggctt aaaaataaaa aaggcaaaaa tataaaagcc aaacccgggg ccgcactttt 21301 ggcacagaaa tcaggtgctc cgattttgcc tgtggcaatt tcaggacgtt accgtccttt 21361 cagtaaaata aaagttgttt ttgggaaacc atttactctt gatttagaca aaaatacgaa 21421 atatactaat agtgaattgg ttgaattcag tgaaagtata atgaaaaaag tttattcact 21481 tttgggggag tattaatttg gagataatag ttgctaaatc agccggtttt tgtttcgggg 21541 taagtaacgc agttaaaacc gtcaataatc ttctggaaaa tcaaaaagag cccatataca 21601 catacggtcc tattattcac aatgcgcaag tagtagatct ttttacttcc aaaggtgtta 21661 aaaaaattga tgatattgac gaagcagagc ccaacggtca tattgtaatc agggctcatg 21721 gtgttacacc ggacatttat aaaaaaattt cagacaaggg gttgattttg gaagatgcta 21781 catgtccata cgtaaaaaaa attcacaacc ttgtaaagga gaaaagtgag gaaggctaca 21841 agataataat tgtaggcgac aggaatcatc ctgaagttat agggataaat ggatggtgta 21901 acaaccaggc atatatagtt gacagtgttg acgatgtaga aaaatttccc acaagcgacg 21961 aaaaagtttg cgtagttgca caaacaacga taacaaacga aaagtggctc gaggtaaaca 22021 cggcattaaa aaagaaattc aaaaatattt taaaatttga tacaatatgt agtgcaacca 22081 gcagaagaca aaacgaagca gaagaaatag caaaaaaatg ttgatatgat gattattatc 22141 gggggaaaaa acagttcaaa cacccaaaag ctttatgaca tatgtaaaaa gcattgcaat 22201 ctgacgtata aaattgagac ttccggtgat ttgccaccgg tagacataaa aaaataaaaa 22261 aagtaggtat ttctgccgga gcttctacgc cggactgggt aattgaggag gttattaaaa 22321 aaatgagtga attaaacaaa caaggaatgg tcgatatttt agaaaatgat ggtgaaatag 22381 atttcgccaa tgcttttgag aattcgtttg tcagaataca tgcaggagac actgtaaagg 22441 gaaaaataat tggctttaac agcaatgagg ttttcgttga cttgggttac aaggctgacg 22501 gcataattcc tctcgaagag tacactgacg accctaactt caatattgaa aaggaagtaa 22561 agattggaga agaagtcgaa gttctcgttg aaatggtcaa tgacggcgaa ggcaacgtaa 22621 gactctcaaa gaggaaagtg gatgccataa aatcttggga tgacatagtt aaagcctatg 22681 aaaacaagac tcctgtaaac gcttatgttg ttgaagttgt aaaggggggc gtaattgcca 22741 gctacaaggg cgtaagaata ttcgttcctg cttcacaggt aagcgataga tatgtaaagg 22801 atttgaacga attcctgaag agaagcataa ctgtcagaat tttagagctt aatgaaaaaa 22861 gacgtaaagt ggtaggttcc gcaagggtga ttatcgaaga ggaaaaggaa gctcttgcca 22921 acaggacatg gaacagcatg gaagttggaa aagtattcaa aggtactgta aaaagtctta 22981 ctgatttcgg tgcttttgtt gatataggcg gagttgacgg acttatccat atttcagaac 23041 tttcatggac aagagtcaaa catccgtctg aagtattaaa agtcggagat gaagttgaag 23101 taacagtttt ggagtttgac aaagaaaaga aaaaagtatc tttgggatat agaaagatgg 23161 aagacaatcc atggtataaa atagaagaaa aatacaaagt tggtgatgtt gtcaaggtaa 23221 ccgttctccg ttttgctccc tttggtgctt ttgttgagct ggaaaaaggt gtggacggat 23281 tggttcacat atcccagata tcttcaaaga gactggcaaa agttgaagat gctcttgaga 23341 ttggtatgaa agttgacgca aaaataattg aagtagacgg cgaaaacaag aaaatcagcc 23401 ttagtattaa agaggttatg ccgatagatc ctccttcatc aaagagtgaa tccaaagcaa 23461 aggacggatc cgaagcaaaa gaaacctctg ccaatactga agaggaagct gaaccgacag 23521 agcataggga agacatgaac gtaacagttg aagatttggt atcaaaaaca acgcaatctt 23581 aataacaata attttaataa tatatcttac tttttatcat atctgtgttt tagccgaaga 23641 tttgtttgta aattgctttc aaagcctgtt gcaaaacgta gcaggctttt cgtttgctta 23701 tatttttgca tgttttggca tgattataag tgtaaacatg ataaaaatgt ataaaaaata 23761 aagcaaaccg aaggagattt ttaataattc agaataaaca agatatatta aaaattttag 23821 aaaaatctat tgacatttag tacagacgtg ctaaaataaa ttttgttgaa attgaccaat 23881 ttcaaattaa aagaaaggtt gttgatactt ttaaaaattg aaggaggaaa tgcaatgaat 23941 gctttgggcc gtcatatttt ggcagaaata tatggatgcg atgccgcaat acttaacaat 24001 cgaaatttga ttgagaaaat catggttgaa tccgctctcg aagctggtgc tgaagttaga 24061 gaagtggcat tccacaaatt cagtccccag ggagtaagcg gtgtggtggt tatttctgaa 24121 tcccatttgg caatccatac atggccggag ttgggatatg ccgcagtaga tgtgtttacc 24181 tgcggggaaa aagttaatcc atgggatgct tgcaattacc tgactgaaag gtttaaagcc 24241 aagcatatga ctgcaaccga ggtgaaacga ggagtcttcg aagaacctgt taaagttgca 24301 aatttataat tgttaaaata gatctttaaa agcgtgccgg tatgcacgct tttatgtttt 24361 atataccgta ttgcacattc atttattccg atttttcccg cacaacatat tatatattta 24421 tttttaacca tctgtatggt aaaataatta taatgttgca gtcatatcat atacatcggc 24481 ctgttcttta aatttttatt ccattcaatt aagagaggag taggtatgga aaggacactt 24541 gttatattaa agcctgattc tgtaaaaagg aagcttgtcg gtgaaattat atcccgtttt 24601 gaaaaaagaa atttcacaat ccttcacttg aaaatgatga atattgacag ggaattggcc 24661 tgcgaacatt attcccatgt aaaggataaa ccttttttca acgatatgat tgattatata 24721 acatccgggc cggttgttgt aatggttctt tccggataca gggtaattga ggcggtaaga 24781 agtatggtcg gtgcgacaag caattttgat tccaagcccg gtaccatcag gggtgattat 24841 ggatatcaca gatttgaaaa tcttatccat gcttcagatt cttgtgaaag tgccgaaata 24901 gaaataaaga ggtttttccc cgaactggat tcgtagatcg ttatacaaaa ctaaatacac 24961 aggttacaga ttcatacttg cagtcgatac aagatagccg gtttttgtca tttaaaaata 25021 cgaatggaga gatggcaaaa tggttatgga ttacgaaggc tttaagaaag aaatattcaa 25081 gctgaccgga attgaccttg gctcttacaa agaaaaacaa atgaaaagac ggcttgactc 25141 cctgataagc aaaaataatt tcagcggcta taaaacatac attgaagctc ttaaaacaga 25201 taaaaaactt ttcaatgaat ttatcaacta tatgaccatc aatgtatcag agttctacag 25261 aaatccggaa cagtgggaaa aactaaaaaa tatcatactt ccgtcacttc tcgaaaaaaa 25321 tagcaatccg aaaatctgga gtgccgcctg ttcgagcgga gatgagcctt atactcttgt 25381 tatgatactg aacgaatttt taccgcttaa caaaataaaa attatcgcca ccgacataga 25441 cgccgaaatc cttgtaaaag caaaaaacgg gctttacact gagaaaagca ttgccaatct 25501 gccaaaaaaa tatgttgaga aatattttaa agtagacggc gatgtatatg ccataaacca 25561 ggaagtaaaa aattgtgtcg aatttagtaa acacaatctg ttggcagacc cttatccaaa 25621 aaactgcgac cttatcgtat gcagaaatgt acttatttat tttaccgagg aagcaaaggc 25681 ggaaatttat aaaaaattca acagagcctt aaaaaccggt ggtgtgcttt ttgtcggaag 25741 cacggaacag ataatacttt ataatcttta taatttcaag cccatacaaa cgttctttta 25801 tcaaaaggaa aaagatattt agagaaaaaa tactttaaag aaaaaatgtt tcgggaaggg 25861 gagttgtatg tttaaacgaa ttgcagcctg gatacttctg gcaggctttg tacttttgct 25921 gcttaacatt acagtattcg gaatttatcg tgagataagc gcagccatct atcttgtcgt 25981 aatgataatt tatatttttt accttattgc gaataagaaa taataaagag aaaactcaat 26041 cataaagtat atatgaacca cttccggcaa atactcatat tatagaatac ttcttgcttg 26101 cggaggtggt ttttatggta gtggcagttc agaaagggct cgacaactta aagcgggaac 26161 tggcaaaaag aggtttcgag gttgtcgatt tggaaaccta caactatccc atagacgcta 26221 ttgtatatga aggaaattca tttcagatat cctatgtttc cagaaacaac atgcctcaaa 26281 tgaccgcagg tcaaaggtca aactacggcg tattcattgt caatgctctt ggtaaaagca 26341 tcaacgaaat agaagacatg cttcgtacaa gatattacag tcctctcttc gagctaaatt 26401 aagtttcata aaagcttaaa tttcatagta aatttattat caaaacaata cgatatatat 26461 tttttcaaaa atattgacaa gcatttcaca aagtgctaat ctaattgtgt gaatacctag 26521 taatgcagtt ggaattgggg gattggcttt aatgtggtta tctaccaaag gaaggtatgg 26581 gttaaaagcc atgcttgatc ttgccctcca caacggcgag ggaccggttg ctttaaaaag 26641 tattgccgag cgccagaatt tgccggaaaa ttatttggag caactttttg caactcttaa 26701 aaaggctggc catattacaa gtgttagggg tgcacaggga ggctatttgc tttccaaaga 26761 ccctgacagt attacaatag gctcgatttt aaggtcactg gagggttctc tcgcaccggt 26821 tgattgtgtt gtggaagaca gttctccaaa atgtgaccgt tttgacaact gtgttacgaa 26881 aatagtgtgg gaaaaaataa gagacagcgt caatgaagct gtagattcca ttactttggg 26941 ggatctcgta aaagaatcca acaaaaattc cgcactttct taatatcggc cacgtttaat 27001 actttatttt attatgagat tttgttttta gatatgcgtt ttggggaata aataaattaa 27061 aataaattaa aaatttattc taaactatac tatagttaag gagtaatctt tatgagtgac 27121 aacaggtttg tttatcttga tcacgctgca acaaccccgg ttaaaccaga ggtacttgaa 27181 gctatgcttc cgtacttttc aaataagttt ggaaacgctt cctcaattta ctctatagga 27241 agggaaagca aaaaggcaat tgaggaggca agggaaaagg ttgccaaggc aattggcgcg 27301 cttcccaggg aagttttctt caccggttcc ggcaccgaag cagataattg ggctatcaaa 27361 ggtgttgcat atgccaacag ggacaaaggc cggcatataa taaccactgc aatagaacat 27421 catgcagtac tccacgcatg tcagtacctg gaaagtgatg gctttgaggt aacctacctg 27481 cctgttgatg aaaacggttt ggtgtcgcct cagcaggtac aagatgcaat aagacctgac 27541 acaatactca ttacaattat gtttgccaac aatgaaatcg gcaccattca gcccatagcg 27601 gaaataggta aaatagcaag ggaaagaggc gtaatatttc ataccgacgc agtccaggca 27661 gttggaaata tacccataaa tgttgttgac ttgaatgttg accttctgtc aatgtcaggc 27721 cacaagtttt atggaccgaa aggcgtaggt gctctgtaca tcagaaaagg tgtaaaaatc 27781 gtatcgttta tgcatggagg agctcaggag agaggccgca gagcaagtac tgaaaatgtt 27841 gcaggtatag tgggcatggg taaagccatc gaacttgcag tggaaaatat ggaagaaaat 27901 aataaaaagc ttattgaatt gagagacagg acaatcgagg aagtaatgaa aaagatacct 27961 tttgtaaggc tgaacggaga cagatacaag agacttccgg gcaacgtaaa cttctccttt 28021 gaatttatcg aaggagaatc ccttcttctg atgctggaca tgaagggtat tgccgcatca 28081 agtggatctg catgtacttc aggttctctt gatccgtctc acgtactgct tgcaataggt 28141 cttcctcatg aaatagccca tggttctttg aggcttactt tcggtattga aaacacacat 28201 gaagatatag attaccttat ggaagtactg ccaacaattg ttgacaggct aagagaaatg 28261 tctccattat atgaaaaagt gaaaagaggg aattaatatg atgtatagtg aaaaggtcat 28321 ggatcatttt atgaatccca gaaacgtggg agaaattgaa aacgccgacg gtgtcggcga 28381 agtcggcaat gcaaagtgcg gagatataat gaagatgtat ctcaaaattg aaaacgatgt 28441 aatagttgac gcaaagttta aaaccttcgg ctgcggagcg gcagtagcca caagcagtat 28501 ggcaacggag cttgtgaagg gtaaaactat tgaagaagct ctcaaaataa ccaacaaagc 28561 cgttgcagaa gctttagacg ggcttcctcc cgttaaaatg cactgctcaa atctggcaga 28621 agaagccatc cgtgccgcaa ttgatgatta cagacgcaaa aatgggcttc ttcccgaagg 28681 cagtgaaaac aatgcttgcg gaagaagatg tgatgacata catcacggta ttgatgacga 28741 agattaaagg tggattttag tcacaatgag caagaagaag gttatggtag gcatgagcgg 28801 cggcgttgac agttctgtag ctgccgccat acttttggaa cagggatatg aggttatcgg 28861 agccacaatg caaatttggc cggatacaga tgaagaaaca aagcttgttg aaggcggatg 28921 ctgttcgctt tctgccgttg atgatgcaag gagcgttgcc aataaattgg gaatccccta 28981 ttatgtttta aattttaaag acatttttga aaaaagtgtt attaactact ttaaagacga 29041 atatctaaag gggagaaccc cgaatccttg tattgcgtgc aacaggtttg tgaaatttga 29101 atcaatgctg aacaaagccc tgtcgatggg tattgactat attgccacgg ggcattatgc 29161 aattataact tatgacgata ataaaaaaag gtatctgctg aaaaaatcgg ttacccagca 29221 gaaggatcag acctatgccc tttacaatgt tacccaggaa cagcttaaac atattcttat 29281 gcccataggc aatttcacca aggagcaggt gagggcaaaa gctaaggaat tggggctcta 29341 tgttgcatca aagcctgaca gccaggaaat ctgctttgta aatgacaatg actatggaaa 29401 gtttatagaa gagaataccg acaaagaaat taaacccggc tattttgttg atacaaaagg 29461 aaacatatta ggaaaacaca gaggcataat tcattatacg gtgggacaaa gaaaaggcct 29521 tggtattgct ttgggaaaac ccatgtacgt tgtaagaatc gatgcggaaa acaacaccgt 29581 tgtgctgggt gatgaaaacg aagtttattc aaaagaactt acagcctatg acttaaactt 29641 catttcaata gacaagcttg aagagccaat gagagtcaag gctaaaatac gttattccgc 29701 caaagaggct gatgcggtta tttatcctct tgaagacggc aaagtcaggg ttgtgtttga 29761 cactccccag agggctgtta ctcccgggca gtcggtagtc ttttacgacg gtgatatagt 29821 tgtcggcgga ggaataatcc aatagataaa attattaatt aaatctcttg taaaaaccaa 29881 acttattgtg ctaaaatatt caataagctt caaagagcaa aagacgatga gggagaggca 29941 gtagtcgttc atgggtgaca gtcagagaga agtccgggcg gtgagagggc tttcgtacat 30001 gaacgggcga attacaactc ctaagttgca tacgtgaaat atttttcatg tatgacggcg 30061 gccaaccgtt atatcggcag taataaatga ggtatatatt tttttaaata tatacaaatt 30121 aaggtggtac cacgggagct ttctcgtcct taagcagggc gaaaaagctt tttttattaa 30181 acccgtaaat ttagataaat tatttaaatt ataaaaatta attaacatga aattcaagag 30241 aattttaata aaatttccag gaggtatcta tatgtccagt gtgtttgaaa ctttgaaaga 30301 aaggggatat attgcgcaac ttacccatga agaaaaaata aaagagcttc tagaaaagga 30361 aaaaattaca ttttatatcg gatttgatcc cactgccgac agtcttcatg tgggacattt 30421 cctgcagatg atggtcatgg cccacatgca aaaagcggga cacagaccca tagcgttaat 30481 cggcggcggt acagccatgg tcggcgaccc cacagggaga actgatatga gaaaaatgat 30541 gacccgggag gaaatcaagc ataatgccga ttgctttaaa aagcagcttt ccaaattcat 30601 tgaatttgga gaaggaaaag ccataatggt ggataacgct gattggctgc ttgatttaaa 30661 ttatattgaa tttttgagag atataggagt gcatttttcc gtcaaccgaa tgttgacggc 30721 agaatgtttt aaatccagac tcgaaagagg tctttccttt atcgagttca actacatgct 30781 catgcaaagc tatgacttcc tgaaactgta taaggaatac ggctgtatca tgcagctcgg 30841 cggtgacgac cagtggtcaa acattctcgg aggaatagat cttattagaa gaaaagaagg 30901 aaaagaagtc tatggtatga cctttacact tcttaccacc agtgaaggca aaaagatggg 30961 taagacggaa aaaggtgcat tatggctgga tgccaacaag acttctcctt atgagttcta 31021 tcagtactgg agaaatattc atgacgcaga tgtgataaaa tgcttaaaac tcttaacctt 31081 tgttcctatg gaagaaatcg aagagtatgc aaaacttaaa gatcaggaaa ttaacattgc 31141 taaaaaacgt ctggccttcg aagttacaaa gcttattcac ggtgaggaag aagcattaaa 31201 tgcccaaaaa actgcagagg ccttgtttga aaaaggtgca agcactgaca acatgcctac 31261 tactgaagta gcctccggtg agctttccaa cggtataaac ataattgacc tgcttttaaa 31321 aacaaagctg attccttcaa agggtgaagg ccgccgactt atcgaacagg gcggaatttc 31381 tgtaaacgac gttagagttg aaggttttga cagattagtc accatggatg atttcaacaa 31441 cggagagtta attattaaaa agggtaaaaa gacataccac agggtaaaac ttgtataaaa 31501 cacaaaaaag acatagaaaa caagcttaga ggtttgcatg cctctaagct tcttttaatg 31561 tttaaagctt gttttaacgt ttaaagttgg tttttaaggt tttaaaggtt tattttaatg 31621 ttaaaaaaac ttgtttttta tgcttgaatg ttgtttttaa gtgtccaaat ttcatttaaa 31681 ttgttaaaat ctttatttag attggtgtaa acacaggttt tctgttttca aaatgcgccg 31741 tatatttaaa acccgcattt ttaacaagtt ctttcacata gtcgaattta taaccaatat 31801 actcgggggt atgggcgtca gagcttgtac aaattatctc accctttagc tctctgtacc 31861 tttttataat ttcatagtcc ggcattggcg aatctaaatt gtatcgaaag ccggaggtat 31921 ttacctccaa acctttgcct ttttcaacga gagccttgag tatggcatca actctgtctt 31981 tgaaatcgtc caattttaac gtcttgtcat cataacatcc ataccttctg atgagatcaa 32041 tatggcccaa aatatcaaaa ttatcaaaaa ggtttatgca ttccaaaact gcttcaagat 32101 atctcaaata ggcttcattt ttggatttgt tcctgcaaaa atcgccgtta tgaaggtcag 32161 ttttgtcaac aacgtgaatc gagccaatta caatatcaaa atcatatttt tttacaatat 32221 catttgattc ctctataaca tggggttgta tacctacttc aatacctttg agaactttga 32281 ttttgccgga ataatcccgc ttaagcctgt ccatggcctc agaatatttg tcaaaatcaa 32341 tcatgaatac atcatcataa tccggatagt ctatatccaa atgatctgta aacgaaatac 32401 cttcaaatcc caatttcatg gcagtattaa tggcaatttt cgggtccatg ttgctgtctc 32461 ctgaaaagct gctgtgaaca tgacaatcat acattgtatt tacctccaaa tttatttcga 32521 tgttaagtta aagctgctat tatttattta tagaataaat acggtaatta gtcaagaaac 32581 cgacatgtaa acaaagaaac cggatattga tgatagtcct aaagaaatgg gactataaaa 32641 ctatttcgta aatattgcaa aaataaaaaa ataaagtaaa ataataagta agagtgagat 32701 tttgtgtctt ttttaaatgc atcttatttc acacaattga tacttgtcaa tattgcatgc 32761 ttcaagtggt tttatttgtt agatagattc ttttttaaca tttcagtatc agactgtcgg 32821 acaccgctgt acttttattt gcccgcactc tactgaggag gattttcata tgagaaagag 32881 aataatcgaa gtatcaacgg actacaaaat ccttattgtt gatgatgaag aaggcataat 32941 aaattcaatg aaagtaatgc ttacaagaag tggatatttt tgcatgggca tttccaatcc 33001 tttggaggca atagaaactc ttaaaaaaga gcatttcgat atgcttattt tggattacat 33061 aatgtcacct atccatggag atgaggtcgt tgcaaagata cgagaattca acaaggacat 33121 ttatatcctt ctcttaacgg gtcacaaaga cttggctcct cctcttgaaa ccatcaaggc 33181 tcttgatatc cagggatatt gcgaaaaggg agacaagttt gaccagcttc ttcttttaat 33241 tgaatcagga ataaaatcaa tatctcaaat gcgcaccata aggcagttta aagacggttt 33301 aaacagaata cttcaggctg ttccaaaaat ttatcaactc cagccgatag gagttatttt 33361 ggaagaaata ttgcagggcc tgatgcctct tgtaaacagc aaagatgctt tcattctggt 33421 agatgattgc aacagcggtg aagggaaaat catctttaag ggagtcggtg aatacgacat 33481 caaggcagaa tcgctggtta ccatgctgag ccctgaactt atggaaaata taggtcgtgc 33541 aagggacagc aagaaagttc tgctcttaga ccatggaata atacttcctc ttacgaacga 33601 gcaaaacaaa tccattggag taatttacat tgaaagcagc aatttgggtg acggaataaa 33661 actccttgaa atatattcca cacaggcggc ttcatctatt aataatgcat ttttgcattc 33721 attaatcaac atgaagaaag aagagcttga cagaacctat caggagctta ggaaaagata 33781 tattgacaca atagaagctt tgcgtctgac agttgatgca aaggatatat atacaagggg 33841 tcattcggac cgtgtcgcat actatgcggt aaagctgggt gaagccttcg gacttccgga 33901 agatcagttg gagcttctca aagtgggcgg tattttccat gacataggaa aaatcggcac 33961 ggccgatgat attcttttca aaaccgacaa gctgagctac gatgaatatg aagaaattaa 34021 aaagcatccg ttaaaaggtg cgtacatact ttcggccatt tcaatgttca aggatgttgt 34081 tccgctggta aaatatcatc atgagagaat tgacggtaaa ggttatcctg agggattgaa 34141 aggggacgag attccgtttt tggcaagaat attaacggtt gccgatgcct ttgacgctat 34201 gatgtcggac agaaaataca ggtcaaaact tagcctcgaa gaaaccaagg agcagtttag 34261 actgtattcc ggtacccagt ttgaccccca ggtggttgaa aagctttttg agattcttga 34321 aaactatgat ttgatgcttg aagaactgtc aaaaactttt acctagttgt gtaaataata 34381 tgccctgaca taatattgta atatttggat taaaaagaag agcatatact cttctttttt 34441 tatcaccact tgtaatttcc gaaattcttc tttctacaat gtttattgtg aaagcattta 34501 gagatataat aataaatata aagtttttgc aggagggaat aaatatgtca gacaataaaa 34561 ccgcgggaca aaagttgtgg gaaaacctgt cctacaactg ccccaatgtt tggaacaaaa 34621 taggtaatga tgaaataaaa aacacctttg cattttgcga agaatacaaa tcttttttag 34681 acaaatccaa gacagagaga gagtttgtgc gcgaaactaa aaagctggct gaaagcaaag 34741 gttttgtttc aatagacgat gtaatagatt ccggaaaacc gctaaaaccc ggaatgaaag 34801 tctacagagt attcaaaaac aaaatcgtgg cccttgcagt tataggctca cagccgccgg 34861 aaaaaggttt taaccttgta ggagcgcata tagactcacc aagaattgat cttaagccaa 34921 acccgatata tgaggcaaat gaaatggtat ttctgaaaac acattattac ggaggtataa 34981 aaaagtatca atgggtaacc ataccgctct ccatgcatgg agtgatcata agaaaggatg 35041 gaagcagtgt cgaaattgta atcggcgaag atgaaaatga tacagtgttt acaataaccg 35101 atttgcttcc gcaccttgcg gcagaacaaa tgcagaaaaa aatgagcgaa ggaattacag 35161 gagagaattt gaatattctt ttcggttcaa ttccctataa cgatgaaaaa gttaaggaaa 35221 aggtaaaatt aaacatactc aagctgctta atgaaaaata caatataacc gaagaagatt 35281 tactgtccgc ggaattggaa ttggttcctt cttttaaggc aaaagatgtg ggtttggata 35341 aaagtatggt cggtgcctac ggacaggatg acagagtttg tgcttacaca gctttaagag 35401 ccgtcctgga tttggataac gtcgacaaaa cagctgtttg tgtacttacg gacaaagagg 35461 aaataggaag catgggtaat accggagccc agtcaagctt tcttgaaaac ttcattgccg 35521 atatatgcgc attaagctct gaaaagtaca cggacataat tttaagaaga tgcctgagca 35581 attccaaaat gctttcagcc gacgtcaacg cagcaataga tccaacctat gaaggagtat 35641 atgacaaact taactcttcc ttcatcggaa aaggaattgt tcttttaaaa tataccggtg 35701 cccgtggaaa atcgggtgca agtgatgccc acgctgaatt tatgggagaa gtgagaaagc 35761 tgttcaatga aagaaaaata ttctggcaaa ccgccgaact gggcaaagtt gatcaaggtg 35821 gaggaggcac aattgcccaa tttgtagcca atatgggaat ggacgtaata gactgcggag 35881 tagctgttct ctcaatgcat tctccgtttg aagtaaccag caaagtggat atttatatgg 35941 catataaggc ttacagggag ttcttgaagt atatcaaata aaaataatga ctcacaacgc 36001 aaactctctc aaacttttga aaggtttatg ttgtgagtca tttattttac ttataccttg 36061 tcctgaaata ctcatttata atcttgtctg tttcctgaga gtcaattaca tagtaccatg 36121 ctccgtccaa tacggatttc ccaggaactt tcaacatgtt tatgctgtcg gcctgaacct 36181 ttgaaacgct tccggtcagc tttaaaactt cactcatatt aagattggtg tcaatattgc 36241 tgaaaatggt actggcaata tcatctactt tagtcagata aaaaatatta agtttctgcc 36301 taaccagttc gcggataaaa ttctgctggg catcaattct tttcaggtca cttccgtcat 36361 agtattcgtt cacacggccg ttgttatact gcctgaacct cataaatttc tcggccatgg 36421 caccgtcaaa atgatgctgc cctttcttta tatgaatact aagtccctgc aaaggatcat 36481 cataatccat gtccaccgga acgtaataat ccactccgcc caaaatatca attatttttc 36541 tgaaagaaga agtatctaca aaaacatagt attttacatc tatgccaaaa agctcgctta 36601 ccgtctgaac tgcaagttct ccgcctcctg tggggtaagc ggagtttatt tttgctttct 36661 tgccgtttat cttaactttc gtgtccctcg gtatcgaaag aatacttact tttgatgtgg 36721 aaggcttgaa atttaccaac atcattgtgt cggtattgtt gttaaccttg tcaccgccca 36781 acaccagtac gttcaaatcc tcgttaacac cttttaaagg acttaaaata tcatcaatca 36841 gtgtccccga attgtcaaca ggtttttcga catccgtatt gaaattgatg tataaaaggg 36901 tcagtgaacc gataaaaaac ataaaaactg acaatattga acatacaatt aaataaaatc 36961 ttctaaaatt catatcgcaa ctccattttt ccaagtgtat tttataccag aaataaagta 37021 taatctattt tttctaatat ttcaattatg ttcgcaagcc tgacgtcagt attttatcgc 37081 aaaaattgca attaaaatca atactgccaa agtggattca tttaattttc aatattatag 37141 attagctctc attttcattg tcatgctcat cgacataagt tgataaagga ttgctttcaa 37201 cggcattttt caactgctgg ctgtccacat gggtataaat ctccgttgtt gctatgcttt 37261 catgccctag tatttcctga agtgccctta tgtcaacatt gccgtgttta tacattaacg 37321 ttgccgccgt atgtctgagt ttatgggtag aatacctttc cgggtcgagt cccgcagctt 37381 ttatatactt tttcacgata tgctgaacag tcttgttgct tattctttgc tttctggaac 37441 tcaaaaacaa agcatttttg tccttcacac cgtcaacggg ccgaaccttc aagtatgcat 37501 caagagcttt tttgcatgcc gcattaaggt aaatggtacg ttctttgttg cctttgccca 37561 ccacagttaa aacatcattt tttatattgc tcaaattaat gtttacaagc tcggaaagtc 37621 gcaaaccaca atttaagaac aaagttataa ttgcaaaatc tctttcttta tgctctccgt 37681 caatggaacc aagcagcctt ttgctttctt caatgttaag ataccttgga agccttttca 37741 ttattttggg agactccagc tcggcagcag gattttgctc taaaagcttt gccttgtttg 37801 taaggtaatt aaaaaacgac cttatgcttg caacttttct tgccctcgag ctcgcggtat 37861 tgtccctttc acggcttaaa aatgacataa aggaataaat atcactcaaa gttattttct 37921 taatgacatc aatatccatg tctttgatat ctattgagtc aaaatctttt tttgagtcct 37981 ccagaccaaa atgaattttc ataaacctga aaaaaagcct tagatcataa tagtattcat 38041 ggattgtgtt tttcgattta cctcttatgg tctccatgta gcttaaaaag tcttttatta 38101 tagcaggtgc ctcaccataa tacgccccgt tcattttgac atctccctat atattatata 38161 ttttttattt tatatatttt ttcattaacc ggataatatt tttttaatat tttttgacga 38221 aagtttttta gttttgttcg gattacataa aaacatctat atataaatat cgttataaaa 38281 atattataat ataaattttt ataaacaata aatttctaaa ataattaaaa tctacggaaa 38341 taaaaacaac tccaattacg aataaatata ccaaaatggc aaatttaatc aaggggggag 38401 aagtattaat gagaatgttg aaaaagtgta cagggttttt tctatacgta cttgtacttc 38461 tcgtaaatat aatatctgta agtgcattag agccaccacc gatatatggc gactcgaatt 38521 cggactgcaa ggtaaactca acggacttga cattaatgaa aaggtatctt ctgcagcaat 38581 ccattagcta tatcaacctg attaacgctg atctgaatgg ggatggtaaa ataaactcga 38641 gcgactacac attgttaaaa agatatcttt tgggatatat tgattctttc cctgtggaaa 38701 accagtatcc tacaacacct gagccttcac cgacacctac tcccgctgtt gatgaagaag 38761 catggaaaaa caacaccggt acaattgagt tgggagatac gattaaagtc agcggtgaag 38821 gtatttcggt aaacggttcg gtcgttacca ttacagccgg aggagaccac ttagttacag 38881 gtactttaaa caacggcatg atttttgtca atacaaccga aagggttaag ctgagactta 38941 gcggcgtaaa tataaaaaat ccaaacggcc ctgccatcta cttctacaac gttgacaaag 39001 gctttatcac aatagaaaaa ggtacggtca attatctctc cgacggctca acatatactg 39061 atcaggatgc aaaagcagct cttttcagta atgacgattt ggagctgaag ggaaaaggca 39121 ctctctacgt tacaggtaat tacaagcacg gtattgcaag tgacgatgac cttattattg 39181 aaaacggaga tatttacgta acagcagtta ccgacggatt acacgcaaac agcggcatag 39241 aaatcaaggg cggaaacatc accgttacgg caaaatccga tgccattgaa agcgaaaaag 39301 attttgaaat gaccggcggt accctcaatc tcactgcaga tgacgatgcg atacactcag 39361 aaaaagacct tgtaattgac gatggagaaa taaatatatt aaaatgttat gagggtattg 39421 aaagcaagac tactattaca attaacggtg gcaaaataaa tataaactca aatgaagacg 39481 gtctaaatgc tgcaagcggc ctttatatca atggcggtga actttacata acttcaggat 39541 atgatggaat tgactccaac ggacctatat atatcaatgg aggatatatt ttctcctttg 39601 gaggcaacat tcccgaagga ggtattgatt gtgactggaa tcctctgata atcaatggag 39661 gaaccctcat tgcagcggga ggttccaaca gtactccttc aacttcaagt actcagtgct 39721 cggtgctttt aggcagtgga acggcaaact ccgttatcag tatccaaagg aacgggtctg 39781 aaataatcag ctttacggct ccaaagaatt atcaaaacat ggtattcagt tcaccggatc 39841 tcgtattgaa tgcaacttat gttgtatata gaaacggagt ccagtcggta acctttacca 39901 caaattcaat tgtaaccaac gccggaggta gttccggagg atggttcccc ggaggaggat 39961 tcccaggagg aggattccca ggaggcggtg ggggatggtt cccaggcggc ccaggatggt 40021 aataaacgag tcgctgtcaa ttaaacagat agaactgtta acttgttaat tttaaatata 40081 taatagtgtt cggtagccat accgaaataa atatgcataa gacaacagcc tgtttataca 40141 gactgttgtc ttatgtatga ttaagtaata taatattgta ttataattgg tataattaaa 40201 aatattattt agaagggaaa gattgctaat gttggatatc gctttaaatg ctaacatcaa 40261 ctcaacatta actctgggga gtgctttttt aactatcata gtttcatttg ctttgggaat 40321 attaatcagc gttacatata tgaaaaccca tgtaaaaggt tattactcgc aaaatttcac 40381 tctgacattg attctgattc ctgcggtaat tgcagtgata atccttctgg taggaagtaa 40441 cgtcgccaga gctttcagtc ttgccggtgc tttttccatt gcccgtttta gaagtgctgc 40501 cggagaccct aaagatatcg catatgtgct tttttcaatg gccgccggac ttgcctgtgg 40561 tacgggattg tttggctatg ctgcactttt taccgtgttg ctttgcgtgt ttatggttgt 40621 tctgtgtaaa attaatttcg gtgcaaagaa gagctgtgag aaaatactaa aaatcttgat 40681 tcctgagaat atgaattacc agggagcatt tgacgacatt ttaaagaagt atacgacaaa 40741 ctaccagttg tgcagagtta agacaaccga tttgggaaca cttttcgaac ttgtatacac 40801 agtaaccatg gataatgaaa aagatgaaaa ggagtttatt gatgaacttc gctgcagaaa 40861 tggcaattta agtatagtat tgtcaatgaa tgccgcacca aatgactttt gatagtttat 40921 acactgttaa aagcagttta ttaacttatt taaaatattg aaactgtaat ataaaatttt 40981 tattttttgt tggaacttca taattttatg tgtataatac ccttgtaatt atattaaaat 41041 cgtgaggttg cacaaatgca aaaaagaaac atagtcttaa tcggtatgcc cagttccggt 41101 aaaactacaa ttgggcaacc acttgcaaaa actctcaaca tgggttttat agatactgat 41161 agaataataa tggagaaaga aaaaaggccg cttagagaca tcgtaaatca tgacgggctg 41221 gaaaagttcc ttgagataca gcagtcaact ttaatgagcc tgaacgtgga caaccatgtc 41281 atatcaaccg gcggcagtgt cgtttacaat gaagccgcaa tggaacatct taaaagaaac 41341 agcattgtgg tgtaccttaa actggaattt gatgaaatta aaaaaagact gtcttccggc 41401 agaaggcttg caagagacag taacaagagc tttgaggatg tttacaaaga gcgggtgcct 41461 ttgtatgaaa agtacgccga cgttacaatc gactgttctt ctaaaaatgt tcagtcaatt 41521 gttgcggaaa ttaaaaatgt ttatgaaagc atgataaagg gaatataact gatgacagta 41581 gcggaaattt attgtcttct tatgagtttt tataagggag agatgtagga tggtaggaaa 41641 tacattcggc agaatattca gggttacaac ctgtggagaa tcttatgcag gtgcttttcg 41701 caaaaatctt caaataccaa aagagttgtt tgggggacta atagcaatcg tggacggtgt 41761 tccgcccgga ataaagctca ctgctgattt cgtgcaggag gagcttgata aaagaagacc 41821 gggaaaaact cctttggata caccaagaaa agaaagggac aaagtatata ttttttccgg 41881 agtaatggaa gatgatatta caaccggtgc tcctgtcggg atgattatac ccaatgacgt 41941 tattgaggat gagcacatta acaagcataa gagctacaaa gaggttgtaa gaccgggaca 42001 ggcaggatat acctttttta agaagtacgg acaatttgca gacaatatag gtgcaggaag 42061 agcttccgga agagaaacgg ctgcccgtgt tgccgccgga gccgtggcaa aggcggtgtt 42121 agataccatg ggtatagatg taattgcttt tgtaactgaa atacacggaa ttaaagccca 42181 ggaaaatatt acttatgaaa tggccaaagc caattatcgc aaaaatgaaa taaactgccc 42241 ggaccttgaa aaagcaaaag aaatgattga agaacttaaa aggataaagg aagaaggaga 42301 ttctgtaggc ggagtggtgg aaataattgc aagaggtgtt ccggcaggtt tgggagaacc 42361 cgtgtttgac aagcttcagg ccacacttgc ccacgcctta atgtccattg gagccataaa 42421 agggatagag tttggcgaag gattcggtca tacaaaatta aagggttcgg aatcaaacga 42481 tgttccttat tacgatgaag cctcaggccg tgtaagattt aaaaccaaca gagcgggagg 42541 tatactgggc ggaatttcca acggcgagga tatcagaatc agagttgcgg ttaagccgac 42601 gcctactatt tcaatacctc agaaaacagt aaacatgtac actcttgaga atgttgaagt 42661 agagtttaac acaagaaacg atccttcaat atgtccaaga atttatcctg tatgtgaagc 42721 tatggtcaga attgctcttt tggatgcttt atatattgca aaaggctata gggcaatcag 42781 cagcaacata gatccccgtt gggaccgttt ataatcctaa ttcaaaaaat aatttgaaat 42841 caaaaaaagc ctcaaaaagc atgataatag cttgtaagag gcttttttta ttatttttta 42901 ttcattttca gttcattata cttttccttt gacttatcct tcttaatggc tcaaattcgt 42961 acttaagacg gcttattgaa agttcctggt ccatttttaa aaactccaga catctttcaa 43021 tagttttact gaattcatcc tcaggcatgt aatatacaag tccatactca aaacctattt 43081 cactaatgct tttccaaaca acctgtgcct caaaagtaag ttcaatattt tcaatttttg 43141 tattgatagt taatatgtca ccttttttaa attcctgtct tgaacacaac gccaagccgt 43201 ctaggctgat atttcttatg taagagaaaa ctctggtgtt gcgacttaaa atatacgcac 43261 acaaggaaac aggaaacctc tgcgtaagcc tcttgtttgt tattgattga atatggttaa 43321 tagtaagagt aaaagtattt tgattgtaat ccacatgttt tacagtgctt tcacagatgt 43381 ttacaacatt atcattctca aatcctatta caaccgggtc actgtcaaaa aagttgtaaa 43441 taagaaaatc tctttcaggt ttgataacaa cattgttgtc aaacgaatta ctgattatcc 43501 ctcgattgct tcttttagcg gaataatgct ttaaagtaac gatttcacca actcttaact 43561 tcataatatc attcccatcc atttattttg ttcttaactg tatagttttg taaaaagtcg 43621 agttgaataa gtccgcaaaa caagagcagc ttcaggatac ttaagatttt aagatagttg 43681 attggaattt acacaggaat atttactatt tactttttta ttatagcata tttttctaaa 43741 gtttttaaga ccttttttat agttaatttt ttatcatagt ataaaaaata aaaaaaagac 43801 taccgtacag aagaaaactt aagctgccgg tagtttggta tgaaggttgg tatagcttat 43861 taagcaactc aattgccata agctattata atatttcgaa tgttctcata ttttgagggg 43921 gcaaaaatta aaagttttat ttatctaaaa aactaaatta atatataaaa acaatatttt 43981 ggcttttttc taaaaaacct ccctccaatt atacaaaatt tttattttgt ataattgtct 44041 gtattttttt taccccccgc ctgaaacctg ataaataaaa atagatgcac taatcaatta 44101 tcaaaacaaa actcttagaa caagctacaa aattttcagg acttaaatcg ataaatccaa 44161 atttataaag caaattccaa ttatttattt aatatatata atctatttat catttaatat 44221 aatccaaagg attggttaca tttccgtcta ttcgaacttc aaaatgtaga tgcgatcctg 44281 tagccgttcc ggtactgccg gcctgggcta tggtttgacc ctttcgaacc ttgtcacctt 44341 tgttaacaag aagcttgctg caatgagcat acagcgtggt tattccgccg ccatggtcga 44401 taataaccgt ataaccgtat ccatcctccc agcccgaaaa aatcacaatt ccattattgg 44461 cagcaactat tgaagctccg taagccgcat caatgtcaac accggtatgc attttatact 44521 ttttgaatat aggatgaagt ctcgtgccaa atcgagaatc tatctttctt gaacttggta 44581 ccggccacac cattgtaccg ccggcataat ttttgatact tccggtactt ctccttattt 44641 gatttgctat ttcgtaagat tgctgaatca gcttgtcttc ctgctcttcc aaacgtctga 44701 tttcttcttc tctttctttg attttgtttt caagcccact cctggatgca accaatgaat 44761 caatattgtt tttctttctg attaattcaa gttgctttgc accttttata tattgaacca 44821 attgcttttt atatgtaaga tcctttttta tatcctgaac tttctttaca atttccttat 44881 cttttttcgc aattgatgaa atcaactcaa gtctttcaaa aaaattaatc agattctccg 44941 aatcggctaa tatattaagg tatgaaacat atgaatttct gtacatcgtt acaagacgtt 45001 cttcaaaggc ttttaaagtt ttggcgtatc tttcttccgt atcttttaac gaagtctcat 45061 agctttctat ttgactgtcc aatgcctcca gttcagaaac caaattctgg tactccaagt 45121 ttgcttcatt ttcggcattt attaattctt ttttctcacg ttcaagttcc tttttttctt 45181 tatctatctc tactttttgc ttgctaatat cattcaattt atcgtctatt tcactcattt 45241 tatcttttaa agaattattg tcagccataa caggaaaaat caaagccgcc gtcaaagacg 45301 ctatcagtac aataataaaa agccttttca cttttactcc tcctgtaaaa aacgaaaaac 45361 taaggaataa attttttctt ccttctatat tatattatat tcttatacta ttatttaaat 45421 tttgtcaaca tttaatcatt ttgcctttta tcctaattaa cttttacccc tttacctacc 45481 gaataattgg ttaacacatt aaaatcccaa tcatatacat atgttcccga tacagcatta 45541 ggcatcgacg gggtatccgc aaaagaaata acagtgcttt cctcttttag tactttaaag 45601 cctattaaag caagaacgcc actgctctca ggattattac tttctttata ttcgtctaca 45661 tttacatatg ctttagcaaa gttaatcaca ccatttttaa cgtcacttgc agccaacgga 45721 agcacattat aatccggatt tgacaaaacg tctccaccgc ccgggatttg tttgtcttca 45781 agcggtttac cggtatcaag gtccactgcc tgcagtatat ttgggtcata ctttatattt 45841 acctgataac cggcaatttt gggtatgttg ttcaatataa tctttgctgt gattatctca 45901 tcttttttgg cagtattctt gtccaataca atttgaatat ttgcttcggc cgaactgctg 45961 gttccatcat tatttgccgt atttgatgtc tgatttgaat tgtccatatt gttattttca 46021 ggagattcat ttggaaccac ggtcccatta acattttccg gcgactgggt gtaaacaggg 46081 tcaatacttt gaagggcatc cctgtttgct tccacagatg cagtaggttt gtttgtctct 46141 ccggatattg tgggctcagc agcatcaggc tcttttcccg tcctgccacc gcagccacac 46201 agaattaaca ttgccaaaac cgtaataatt cctgttttta tcaaacttga ttttatcatt 46261 aacaatcttc ctccaagtat aatcaaattc ctttgcagtt aattaaacaa atgtactgat 46321 taaatttata acacatttga aaaataaatt caattgcatc attttgattt ttaataaatg 46381 aaaaagtgca ggcggcattt cgccacctgc agcattttac ttgattggca gcataagttt 46441 agttgatgct gtccggctgt attaccgaat aattgctgat ttgattgccg taccagtcaa 46501 acagatatgt tcctgaaata cttcccggca ttgcagctgg ttcctcaaat cttatttttg 46561 tagtttgtga cttcaatacc ttaaaggtta tttcccccaa aactccggta gtttcaggca 46621 caccgttttt cctgtactca ttcaggtatg agtatcctct cgcgaaattt aatgctcctt 46681 ttgtcaaatc atgagcggta atatttgtcg gaccgtattc atcgttgttg agcaattcac 46741 agtttgcaaa agtagacctt gtagtaaacg gtgctccagt aacaggatca ataggctgca 46801 atacattcgg atcgtaaact atgtttacct ggtaaccggc gagattcttt atattgttca 46861 ctcttaccgt agcctttatt gtttcaccaa ctgccgcttt attcttattc aactccaacg 46921 caatataatt ctccggtaaa gcaccgccgt tgattggttc gggctggata actttgtaat 46981 ctgttttctt attgctgttc cagtctatca aatacgttcc tgaaacacta tttggcatta 47041 aagcttcatc cgcataaaag ctgactgttg tcttctcttt tttcaatacc ttaaagccaa 47101 ttacacccaa aattcctgtt tcttccggct ttccgtcttc tttgtagtca cttacgtaca 47161 agtaagtacg cgcaaaattg agtataccat tggacaatct atgcgcagcc attgacgtcg 47221 atccatattc ctgttttaca atcagttcac cgtctacaag gtgagttgtt gttgtatatg 47281 ccgctccggt atttggattt accggctgta atacattcgg gtcatatttg atgcatattt 47341 gatagccggc taaatttttt acattattta ccttaactgt agcccttatt atttctccca 47401 ctgatgctgt gtttttgtca aactccaatt ttatataact gcccgatgat acggcatcgg 47461 cattgacagg ttcaggctga ataaccttat agtctgtctt cttattgccg ttccagtcta 47521 tcaagtatgt tcccgaaatg cttgcgggca ttgaagcagg ctcttcaaat ttgatagttg 47581 ttttttcatt tttcaacact ttaaatccaa ttacccctaa aactcctgtt tcttctgcct 47641 tgcctgaatt tctgtagtct tccataaata cgtatatttg tgcaaaattc aatacacctt 47701 ttgttaaatc atgcacgacc attgaagttg caccatattc actgtttaca atcagctcgc 47761 cgtttgcaag cggagttttt gaggtgtatt ccgctccggt atacggatta accggttgta 47821 atacgttagg atcatacttt atatttatct gataaccggc caactctttt atgttattta 47881 cctttacagt agcctttatt atttctccca cagccgcagt attcttgtca agctccaatt 47941 ttatgtagct gtccgttgat accggattag tcggctttgg cgttgaagta ggtgttgttg 48001 taggtgtcgg cgaaggtgtt gtcacagtgg acgaagatat ttttatgaca cccggattca 48061 caactttgta gccggttatc gtatctccgt tccagtcaaa caagtatgtt cctaacacac 48121 ttgaaggcat tgtaatggag ttctcaaagc caatatacgt atcctgcgcc ttaagaacct 48181 taaagccaat tacagccagt gttccggttt tttccggatt atttgaaagt ttatatgcat 48241 ccagatatgt ataggcttta ccaaagttta atatgccttc ggaagtttta ttcgccacag 48301 ctgatataat accgtattct gtgtttacaa gaatagttcc gtcagcaggc atcgacttgt 48361 ctgacattgg ttctcccgta acaggattta cagcttgaag cactgcagga tcatacttta 48421 tatttacctg atagcctgcg aaattattga tgtcactgat attgattgca gccttgatga 48481 tatctcctac ttttgcttgt tctttatcca gcttgagctc tatttgtccg tctgaaaccg 48541 gtcctccggt cggagtagcc gtcggacttg gaccaacagg cgttgatgta ggagacggcg 48601 aaggcttggt tgaacctgtt attttaatta cgtccggctg cacaacttta taatctgata 48661 ttctgttcaa atcccagtca agcagtattg taccactcag gctgcttggc attgatattg 48721 catcttcgaa tctgacagtt gcatctccct cattgagagc cttaaatcca ataattgcaa 48781 gagtacctga tttttcaggt ttaccgctgt ctttgtaatc tccaacatat gtgtaagttt 48841 tcgcaaagtt caatacgcct tctgaaggtt tgttcacagc aatagagatt actccgtact 48901 cattatttga gatcaaatcg ccgctctttg gcatgctgtt tatttttaaa ggctctccgg 48961 tatcaggatt tacagcctgt aacaaatcag gattgtactt aatatttacc tggaaaccgg 49021 ccaaactgtc aaaaccgtca accttcacaa atgcttttac catttcccct acttttaccg 49081 tattcttatc cacttcaatg cttattgaag cgttggaaac cggtgtactt gaaggtgttg 49141 gtttttgcga tggaattgga gtaggtgaaa ccggaatctg tgtaggagac ggtgaaggcg 49201 ttaccgtttg tcctgaaata ctgacagccc cggcctgaat aacttgatat cccagaacat 49261 tgtctccatt ccagtcaaaa atcatagtac cttcaatgct tccaggcatt gaaagtgttt 49321 cttcaaattt aatggttgtt gaagaagctg ctttaagtgc cttaaacgca atttttgcga 49381 ttgtaccgct cttttcagcc attccggaag ctttgtaggc agcaaggtat gtataagatt 49441 ttccgaaatt caatatacct tcttccactt tattcgctac tgccgaaatt gcaccaaatt 49501 caggatttac aagtatggtg ccgtcctttg gcattgtaga ttttccatag ggaacattcg 49561 tatcaggatc tataggctgc aatacttggg gatcatattt tatattaaac tggtatcctg 49621 caatattatc aaaattatcc acctttattt cagcaattat tatatcgccg acaaaagcgg 49681 tatttttatt aagttccatt tttacaattc ccttggatgg tgcagccgac ggtgaaggat 49741 ttaccacgga ggaattgata acagcagatt gaactacggt ataatctgta ataacctcac 49801 cgttccagtc aaagagcatt gtgcctgaaa ggctgcctgg cattgaagat gtattttcaa 49861 attttacggt ggtgggctgc actttcagca ctttaaagcc tatttccgcc aaaatacctg 49921 tttcttctgg tgaattgctg agtttgtaat cattaagata tgtatacgct tttccaaaat 49981 tcaaaatacc ttcttcgatt ttattgagta caccatatat agaaccatat tcaggatttg 50041 acagcaaatt tccgctttta ggcattgtat ttttattcaa aggtactttt gtatcgggat 50101 ttactgcctg taatacggtt ggatcatact tgatgtttac ctgatatccg gcaaaattct 50161 taatattact aattttgaca taagctttga ttatgtctcc tacttgagcg gtagttttgt 50221 caaattccaa tgatatgcta ccactctcca caccggcagc tgacagagta gtcgctggat 50281 atgcagacac agcaaaggat gaggtcattg ccattattat agcaataacc aaaataaagc 50341 ttataccttt cttcatacca aataaaacct cccaactaaa attattatct ctatataggc 50401 attcagaatg ccttaaatca taacatgccg attctccgga tgcaattcac ctggcttccc 50461 aaacttttct ttttcaccat gtattttaca accgggtgta aaagaaaaca taaaaataat 50521 ttttgtcccc ctttccttta ttattgacca ggaagcatcg gtgtcctaag taaaattcag 50581 cacgttatga taaatgacgt ttatatctta tttataaatt taaacaataa taaaagacta 50641 aataaaacca ctcattaatt tgtttggctt tattttgaat taattacgaa cgtttgacat 50701 agaaactatg taattagaaa aacgtatgga agaacgcatc ctgcgaagag atgtatgtta 50761 taacgtaatg tgcatacatt atttgacgtt tgcttatagc aacaaccaac aagacaaatc 50821 acggaacaat gaataaaaac ctaaaggcat ccactttact gccgccaaat tacattatga 50881 aagcaaaaat aaaaaagtct ctatttcaaa tatatactta atatattgtt ctattataat 50941 catattattc tcaacatatt ttaatattct gagcgctact aaacgcataa ctgattattg 51001 gtatttttta atagttttga gaaataattt acaatattct acaatgttcg attctgcata 51061 ttagttcaaa aaactataaa atgactaaaa tatacaaatt ccgtctcact ttcattatat 51121 aaaatatctc gctctgtttc aagaattttt aagcatttca tcgctcacac aaaaatttac 51181 aaacctcttc aaaacttttt atctccacat cttcaggaaa atgtgattcc attgagcata 51241 cagcaagttt ataccctttg tcaatatcat atcttttaaa gaaaaatttc tttttttcac 51301 tttctgatac aaaaataaca ttatcgttct ctattctaaa gaaaaacgaa ttcagcggca 51361 aagaaagacc tctcccgtct gcctttatat agctttcttt caatgtccac aattcaaaaa 51421 aatattctgt tttctcatta tcttcttttg caaaaagatc tgaagcctct tcttttgaaa 51481 aaaatctttt tgcaatgtcc aggtctacct cccgaatttt ttctatgtca ataccaacag 51541 gtttggaact taccgcacat accacccaac ttcccgaatg tgacagatta aaatgaaaat 51601 cgtcatagcc ttcaagataa ggctttccat aagttgttct gttaaatttt acggattcat 51661 tttttatacc gagctttgag caaacaaccg ctcttatcaa aatttccgcc gtcagagaca 51721 ttaatgcgtc ttcatacttt ataaatctct ttattttgtc ctttttttcc ttggggagaa 51781 aacccaatgc cttctcatat aactcttttt taacaccatt tattacattt attccaaata 51841 tatccagaat atattcacct cattaaatat ttaataccgc aatttgcctt tatctctatt 51901 attttgccca tataataata taccatcatc aacaacaagt caattttttt aatgatattt 51961 ttatacacaa ataacagtaa cacatttatt gagccgttaa taatatgtta ttagcttagc 52021 aaaaacattt caaatattct ctaatcttca aggaggtaca tattcatgtc cgagaaaggt 52081 ttctttggag gagtatttga tgacgacact attctttggt tcataattct cttcctgctg 52141 cttttctggt gctggagcgg ctacggatac gactatggag caaagggtta aaggcatcca 52201 atgtaaaaca cataaaagga ggtttgtaga atgtcagaaa gaggctttgt cggcaatgaa 52261 attatatgga taatcgtatt gataatcctc ttctgctgtc tgtgcggcgg attccgttac 52321 taaaaagcct ttaagcatcc gccggttgta tcagcgaaag attacataat ggcacccgaa 52381 gcaaatagct gaaagcaaag gggcttttcg cccctaagct tttattttat tatcgccttt 52441 ttaacttaca caacttcata tccctgatct tcaattgcat ttttgattgt ttcaatttcc 52501 agcttgctac tgtcatactc cacagttacc ttcttttctt tcaaatcaac atctacattt 52561 gacacacctt caaggccgcc aaccgctttt tttatgctgt ttacacagtg attgcaggac 52621 attccttcca ccgtaagatt taaaatatct tttggcatat tacttcctcc ttttcattcc 52681 gggtataatt tattttacca cctttgcaca attgttaaat attaaaatta ttgaatatca 52741 aaataaaata ataaaaaatc actcgaatat ttcggaaata tattttattt ttattaattc 52801 tggtttatca ttataataat ggcaaccata ctataaataa aagagggact ttgcgaatat 52861 gaatacaaaa acatccaaaa tcatacttac tataaatata ataatactgc ttttggctgt 52921 tccggggttt attattctgg ataaatatct tgaacgctca aattccaatc cggacaatat 52981 cgttgcgcca ccttctccgg atgtggcttc caatcccggt gaaactacca taccggacgt 53041 taccgcaagt ccggaaaaca ctgacaccaa aaattggaca gcaataactc ctgatgaaat 53101 cgatattgta aaagagtgtc ttcccgaaag ccacaatttt aaatgggacg ttattaaaga 53161 cggcaagaaa cttgatacat attcaagaga caataccgtt gtttttaaac cggctgatga 53221 atacaatgaa attgacggtg taaccacctt cagaggaaac aactacagaa actccgcaag 53281 ctttggttct gcaaacgtca gggaagaaaa actcgagaaa gtttggagta tcaaaatagg 53341 atatatagat acatggacag gtgttggctg gaacggtcag ccggcaattg taaaatggag 53401 caacgaactt cgaaaaaaaa tgaatttgtt tcaggataaa aaggataaaa atgatctcaa 53461 ggaagtcata tatgccactt tggacggaaa aatatatttt ctcgaccttg acgacggttc 53521 ctacaccaga aatccaatta atgtaggtgc tccgctcaaa ggaagtgtaa ccgtggaccc 53581 caggggttat ccccttctct attcaggtca aggcattgac gaagtaaaag gccaaaaggt 53641 ttcgataggt tttcgcatat acagccttct ggatcaaaaa cttctctact ttataaacgg 53701 ccttgacaat actgctttca gatactgggg agcttttgac tcttcccctc ttttgcacaa 53761 agaaaccgat acgctgtttt tatgcgggga aaacggcctt ttgtattcca taaagctaaa 53821 tacggattat gaccctgcac aacctgctat ttcaataaag cctgatattg taaaatacag 53881 atatgtttct cccgtcaacg gcagacttgg aactgaaaac tccatagccg ctttcaaaaa 53941 tttcggctac tttgctgaca acagcggaac tctccagtgc gttgacttaa acactctgtc 54001 tccggtatgg ataagaaaca taaccgatga tacggacagt acaatgggta ttgaggattt 54061 aggaggaaac aacgtttata tctatattgc aaacgaagtt gacctccagg gagaaaacgg 54121 atacagttat gtcagaaaaa taaatgcttt gacaggaagt cttgtatggg aaaagaaata 54181 caaatgctca tataacgcag atacaaacgg cggaacattg gcctctcccg taattggaaa 54241 aaacgaaatc agcaatctgg ttatattcag catagccaaa tcctataaga aaaacggcgg 54301 aaagctaatt gcctttgaca aaaataccgg cgacgaagta tgggttatag attcggattt 54361 ctacagctgg agttcaccgg ttgacgtata tactgaagac ggcaaagctt atatcattca 54421 ttgcgattcc gctgggtata tgaacctcat tgaaggcaaa agcggcaaaa tccttgacaa 54481 aatacctctt ggcggaaata ttgaaggttc acccgcagtt tatgacaata tgattgtagt 54541 aggcacaaga ggtcagcaaa tatatggaat aagaataaaa tagtcaaaac ttaaagccta 54601 ttttgtattt tcaaacaaga gtttgcattt atccgctctg tactttgata ttacaaattc 54661 taccacttga ccacttttgg aaaatattat gttggatacc ataaaaaggg cttgtccggg 54721 ctgaaccatc aggtattgtg cctcatactg ctctgtatat attatttcca gagtgctttt 54781 cgttttggcc ggaagaagtg gatattttcc tctcagcatg tcataagaag gttttttgct 54841 ttttacatct tctattatat ccgggaagag attcatgggt atatacgagg tattgagcga 54901 aattatgtcc tcaccgtttt tgcttttata gctaatcttc gcaaaatcaa ccacctgatt 54961 attggctatg gaaaagactt cgtcgagttt tttgaaatct ctgtttgtta ttttctctat 55021 tgagataata tctctttcat ttgttatctc gttgtctaaa atagagtcgg taaatcctgt 55081 ataccttttt gtggttattg atgatttggg cttcgaaaca aaagttcctt ttcctttttc 55141 cttgtacaaa tatccattat tggttaactc gcttatagcc tgccttaccg tgggccggct 55201 gatattataa agctcacaaa aatcctgttc tgaaggtatt tttgtgtcag gcgggtattc 55261 gccgctctca attttttcaa taattatatt cttaagctga gagtatagag gcacgttact 55321 atacttgtta atcacgttaa tttccccctg atctgtcaaa gcaaattaat gtaacaggaa 55381 ttaaattatt ttgaaaagca aattgaaacc agtataagac cttgctatca tagacataat 55441 tgtactatat gaaacatcaa atttcaacat ataaatttca acatattttt ataaaaaaag 55501 actcggcaac ccaaagctta aaataccaat tgccgagtct gtttctttct ttatcaaacc 55561 ttaagttcaa cctctatatc ctcaacctta ttcttttcaa gaacaggctt tacatattca 55621 ttgataaact cctccacctg ctgcggagct cttccaacgt agttttccgg agcaagaacg 55681 gaattcagtt cgtcaatgct aagtccaaac atttcatcgg ccgctattct ttcaataagg 55741 tcatttttct ttccttcaac cttaacctgt tttgcagctt ccattgaatg aacccttata 55801 cgttcatgga gctcctgtct gtctccgcct tttttaacgg cttccatcat tatgttctcc 55861 gtagccataa acggaagttc ttccaaaacg tgtttttcta taacctttgg atacacaacc 55921 atgccgtctg cgacatttat atatatgttc agtattgcat ccactgcaag gaaagcctcc 55981 ggtatgcata tacgtttgtt tgccgaatca tccaaagttc tttcaaacca ctgggtggat 56041 gcggtaatcg cgggatttag agcgttaaca ataacatatc ttgccaaagc acaaatcctc 56101 tcggacctca tcggatttct cttgtatgcc attgcagacg agcctatctg atgcttttca 56161 aaaggttctt caatttcttt catgctctga agaagcctta agtcattgcc aaacttgtaa 56221 gcactctgtg caattgagct taagagattt agaattctgc tgtcaagctt tctggtatag 56281 gtttgtcccg atacagggaa aaccttgtca aagcccattt tctttgctat aagcatgtcc 56341 agttttttta ctttttcatg gtcgttttca aaaagattta aaaagcttgc ctgtgttccc 56401 gtggtgcctt tggaacctaa aagtttcata ttggacagaa tataatccaa gtcttcaaga 56461 tccattaaca aatcctgaat ccacaaagtt gctctcttcc ccaccgtaac aagctgtgcc 56521 ggctgaaaat gtgtataccc taaagtggga agatctttgt atttcatcgc aaaatcggac 56581 aatttagata ttacacaaag aagttttttc tttatgagtt ttaaagcctc cgtcattatt 56641 ataatatcgg tattgtcgcc aacatagcag gatgtagcgc ccaaatgaat tatgggcctg 56701 gcatttggac actgttctcc gtaagcatgt atgtgcgcca ttacgtcatg gcgaaactct 56761 ttttctttca tttcagccac atcataattt atgtcatctt tatatttctt aagctcttct 56821 atctgttcat cggtaatgtt aagccccagt tccttttctg cctctgcgag cgcaatccag 56881 agcctcctcc atgtgcgaaa cttcatgtcg ggagaaaaca gttcctgcat ctccttgctc 56941 gcatatcttg aatttaaagg actttcatat gtatttttca aaatcttcaa cctccaacgt 57001 atttcttttt aaaattaact ttattaaacg caacacttat tatacaattt tttatgacgt 57061 aaatccatat ttaatcttta taaacttcaa caaatattta ttgagttttc aagcccttcc 57121 gagatattat tgatattaat atgtgtggaa tatgaaattc tttggtacaa cacattttac 57181 ccacttaaac tcatcctttg tcagaccaat aattgaaaat tctttaccat aatgctccga 57241 agaaaaaatg cttcaccatc tctttgcaaa aataaagaaa accacttaac tcttttcttt 57301 tcatcgaaag cgttgtatag tatttgttca acggtttttt cattaaccgg taaagaaaga 57361 atcgtcatgc gtttgctgct ttctttatca acactgctac taaaaggcaa tatttcattt 57421 ataatattct cttcttcatt ccagcagtca attcttatac tgtctgcttc ttccacgaaa 57481 tactcaatca gtattctcca gaaatcaaat tctccccaca taagtggatt gtaaaaatat 57541 acgttatatg ttcgcatttt attgcagttc aaaaacttca cttttttgta tatctccgct 57601 tccaaaccca taggttattg taaccttatc agttgaccat tctaaactaa aatcatcatt 57661 cgaaaacggt ctatatccat catcagtaag aatctctccg tttaaccgac agataatatg 57721 ggagcccaac ttctggtaaa aaaaccaaaa tatttattca taattccttc cacctataaa 57781 ggttatttta tctatccaaa gcagcgcaca ccttcagact cggtgccgtt tgccacgata 57841 ttctgagccc aacggccttt ctttattata tacaatccca gcacactctt caggacatca 57901 ggaaaataac aaaccggata ggccgtataa atatcaaaat ccgcatactt tgcaatcaaa 57961 taagccacag gaacaatcac gccccatgta tatgcactgt caaaaacaag agtgataaac 58021 gtcttgcctc ctgaacgtat ggtaaaataa gcacagtgtg atatggcaaa aaacggcata 58081 taaaaggcac ttactatcat aaaatgagcg gaaagttttc gcacatcttc ggtcgtatta 58141 tatatacgcg gtattacagg cgctacggcc acaagtacag ctcctattat aatacaggtg 58201 catacactga aaaaaatcaa cttccatgaa tattcttttg cccgttgcat atcccccgca 58261 ccaagggcct gtccaaccat gacggcaacc gccgacccca tcgatatgaa tgccacattg 58321 aacaaatttg ttatcgtatt tgctatattg agagccccaa caacgttgag attgtacgta 58381 gagaatattt gcgtcaatgc tgacactccg actgcccaca aaacttcatt agccagcaac 58441 ggcatgcctt tgttgaatat tgtcagtgca aggcctctcg gaactctcat ggagcggtaa 58501 accccagcca cgaacccaaa ccgtgcagta ttcatatggg tatacacagc tatgatcacc 58561 agttccacat atcgggatat aaccgttgca atggcagcac ctgcaactcc catttcagga 58621 aaacccagtt taccgaatat caatacccag ttaaaacaca ggtttgttaa cacagcagct 58681 acacttgcta ccattggtac cattgtatcg ccgatctctc tgagggtact tccatatacc 58741 tgtgacaata taaaaggcaa aagcccccaa agcattattc taagatagac acgtccgtac 58801 tccagtattg ctgccgcttc cgaaggatct ccttctcctt tgaggaacag agaaatcaac 58861 caatctcctc cggataaaaa tactgccagt gcaactgcca atatcacagc agaagcccac 58921 agtttatatc ttaatgtata tctgagtcct tcattatctc ccgctccaaa gaactgcgca 58981 gcaaaaatgc cggcaccggc caatcctcca aacaccgcaa gatagaacac aaacataagc 59041 tggttggcaa ttgccacgcc ggacatttga gccgttccca cctgtccgat cattatattg 59101 tccagaagat ttacaaaatt ggtaatggag ttttgaatta taatcggtat gacaagtgcc 59161 agtacagttt tataaaattt cttgtcacct ataaacgttc ttttgagcct tggcaaaata 59221 ctttttatgt aaagtgtttt gttcattcaa ctaccctcac gctttctcca gcatatatac 59281 tatctttcta ttttagcata ggaaaaagct caagtccata acaaccatgt aaacctccga 59341 atcgcaaatt gatatccatc accaactttt tttcacttac gctccaaata cagccatccc 59401 tttatcaacg ttttgacttc aataattttt ccacttcctt caaataatca gaatcactgt 59461 taacaactat atccggtgta atgccgcttt tcattacgtt ctgttctttt acattccagt 59521 aaaaacttac aaggtatacc gaaaactttt tatcatcatc tctgtataca agttgtccga 59581 caccttttcc aagggttgtc cgtcctataa cagtggtatt tttcaagtgc tttttaagtc 59641 ccaatgcaag aagttccgca ctgcttgcag tattctcgtt aacaagaatg agtatttgtt 59701 taaactcttt ataatcatca ttagaataaa caggcaacat atctccgctc cggctgatat 59761 aataattcat caggcacctt ggcagcaaat agtcaagaat atcatttgcg gatattataa 59821 atccccctcc gttatctctt aaatcaatta caagagtttt atcctcggaa ttctcaatct 59881 tgtccgcttc ctcaataaat ttatccccga catcctccgt aaagcttttt atttttatat 59941 agacagcgtc tttccccaag tcttttgtct caatctgttc ttctttatat ccatattcaa 60001 gactattttc atccacgcat acggtaaaaa catcatcatc tgctttaata gcttcaatat 60061 actgttttac atcatcaaaa ttaaagtcct tctttgttat aaattcttta ctcttttctt 60121 caaagttatc tatttcatta aaataaaggt atgcctggga tataaaattc accaattcaa 60181 cagctttttt atttataagt ttatcaggat cgaatccttc tggagctgta acccgtgctt 60241 cgctgttaaa attcgtattt tccaggctaa cagcaatgct gaaatttcct ccataagaac 60301 ttttctcttt accggttact gtagtattta ttttttccaa ataataagtt ttcttattga 60361 ttaacaattc ggtgtttgta ccactgatta tttcatttac tatatccagt tcatacaatg 60421 cgccggatat caactcatca aaaatatgct caccctttaa tatataatgt tcgtcggttt 60481 cgtccacagt aaaacctgaa cagattaaat catcagcgtt tatatagcta tagttgctta 60541 aaaccctgcg tttaaaattt tcccattcat cttctgttaa ttccgactca taccacaaat 60601 cataattctc atctttcaaa taaatcttct cattttcaca ccagcaatat atatttgatg 60661 tttcttcaga attaaaattt gtaatattac ccgtttccaa tatttttctt tcgccaacaa 60721 tattgcacaa ccgctttttc gaatcaattt caagtttcgc tgtcatctga atctcataat 60781 ccaaatagtc attgttatat ttcatactat ttttctggtc aacactatat ctttcaacac 60841 tgttcaccat tgcatcattg gtttttgcaa gtatatcttt taccttttca aactctgcag 60901 gctcacaaat agacacaatt tgcttttccc cgtcccataa aaccttcttg ttcaagcttt 60961 ctgcgataaa ccttgtcgga atatacgtac ggtcattgta tataatgggt gcaacatcca 61021 gtacatattc ttttccgttt accaatgccg tgtttttccc tattgtcaga agaatcgtaa 61081 tgttgtcctt ttttacggta acagtcctgt tttttccgtc ccagataata tgtttatcat 61141 cgtcgggaac tccaagattt ttcagaatct ccctgaaagg aagcaaaatc cttccataga 61201 gatttaacgg tacattgctg tattcaccga acttgccgtc aattctgatt tttacatttt 61261 ccacttcatc gggaacatga tcctcggtaa ttttaaactt ctggtgacta gaaccgtcca 61321 acctcattct gtaaacacga gtactggaat ccttaacatc atatacctca taatacagcc 61381 attcatccgt aagacttata cctgaaacaa aatcctccac atcacgcagt ttctgtaatt 61441 gcgttccgtc cgttttaatt ctgtatatcc cttcttcaaa aacagaaaag taaatccaac 61501 tatccttaga atttacatta tttataagtt cctcaaacag cggagttaat tcagttccat 61561 caaccttcat tttataaagg aaataatgac cggaaaagta aatccattca ccgtcaatgt 61621 tcaaatacgt atacatatta ccatgatcgc taacttcagt aatttgactg ccgtcatgtt 61681 tcactttata tatacgccca ccattcgcat cattctggaa atatacccat tgattatcaa 61741 catttatgta actagcagaa taatcactca gtttttggtc atcggtagcg tcaagtttca 61801 ttttataagg tttgaaatta tcatcaaacg atgtataata tatccatcca tcatatatcg 61861 taacaaaaag catggattta tcgctaatct tcactctttc cgttccatca ggcttcaacc 61921 tgaacaatcc tgtttcctca gggttatttg tttttgtata tctgcaatag ccgtaaatat 61981 agccgtcata tgcggtcagg ttgtcataca ttccgtcaca tatctttttc ttctggcttc 62041 catcctcttt cattctatac agtccgcttt catcgaaaga ataataaacc cagccgtcgt 62101 attttaaaac acgaccgtta ttggccatat tccccgaagt gtttgaactt tttttcggta 62161 catcaggcaa agccaaagaa cttacagaca taaaaacaat tacacttaaa aaagaaaaca 62221 aaaataacgc cactttcatt tgtttgattt ttttcatttc tattccattc ctttcgtaaa 62281 ggatacattt tctcagggaa attgttattt aaataactat ttgttcccca taatataaat 62341 gatatataat tatacataaa aattcaaact atttactgtt aattacatgt gtcgttcaaa 62401 attttttacc gagactgaaa aatcccattg caatgcaaat cgcacccatt gaaatctaaa 62461 aatttcggcg caataattta tataggggga taaatatttg tccacacctt caataaacca 62521 agtacattta taaataaaaa atttttataa aggggagagg taaatgaaaa aatttttaag 62581 cctcatttta gtcgtttctt ttctgattat gctgctgact ccttcgacaa agatatctgc 62641 agcaactaca ttcaactacg gagaagccct tcagaaagcc ataatgttct atgaattcca 62701 gcgttccgga aaactgcctt ccaccatcag gaacaactgg agagcggatt cctgtctgga 62761 cgacggcaaa gatgtggggc ttgaccttac aggcggttgg tttgacgccg gcgaccacgt 62821 caagttcaac cttccaatgg catataccgc cgcaatgctc gcgtgggcag tatatgaaga 62881 aaaggacgct tttgtgaaaa gcgggcagct taaatacata ctggatgaaa tcaaatgggc 62941 aacggattac ttcatcaaat gtcatcccga acccgatgtg tattactatc aggtgggaga 63001 cggagatatt gaccacatgt ggtggggacc tgcggaagtc gtacacttga gaacaaaaag 63061 accttcatac aaagtagata ttacttcacc gggttctacc gtgtcggcag aaaccgcggc 63121 agccctggct gcggcatcaa tagtgtttaa agatactgat ccccaatact caaatctgtg 63181 cttaaaacac gcaaaggaac ttttcaactt tgccgacaaa acaagaagtg atgccggtta 63241 tacagcggca acaaactttt acacatccca cagcggattc tatgacgaac ttacatgggc 63301 ggctacatgg atttatcttg caacagggga cacaagctat cttgacaaag ccgaatccta 63361 tgttgaattt tggagtaccg aacctcagac agatataatg tcctacaagt ggggacactg 63421 ttgggatgac gtgcgctacg gagcacagct tcttttggca aggattacaa acaagccgat 63481 atacaaggaa agcatggaaa gacatttgga ttattggaca gtcggagttg acaattcaag 63541 gataaaatat acgcccaaag gtttggcatg gcttaataac tggggttctt tgagatatgc 63601 caccaccact gcgtttcttg cggctgttta tgccgattgg gaaggatgca gcccgcaaaa 63661 ggcgaaaata tacaacgatt ttgcaaaggc tcaggttgac tacgcactgg gcagcacagg 63721 aagaagtttc gtagtaggat ttggtgaaaa ttggccacag catcctcacc acagaactgc 63781 ccatggttca tggtatgaca gcatgaatgt gcctgattac catagacatg tgctgtatgg 63841 tgcattggtc ggcggacccg gtgaaagtga caactacagg gacgatattt ccgactatca 63901 gtgcaacgag gttgcctgtg actataacgc aggttttgta ggtgcacttg ccaaaatgta 63961 caacagatat gacggaagac cggtaccgga atttaaagct attgaagtgc cggaagatga 64021 atttatggtt gaagcttatg taagcagcag cgacaaaaac tatgttgaaa taaaaacaag 64081 acttaacaac aggacggcat ggcctgcaag agtgtccgaa ggactctcct ttagatactt 64141 tattgacctt actgaagtaa ttgaagcagg atacggtcca aacgatttaa taatatcagg 64201 cggtcaaggt tcaagcggaa aagtgtcggg cccgcacctg tggaacaaag aaaagaatat 64261 atactatata gaagttgatt acaccggaga tcgtctcttc cccggcggac aggaccacta 64321 tagaagagat tcatctttgc gaattgccgt acccggcaac agtggatgct ggaacagtga 64381 aaacgatccg tccttcaaag gactctccaa aacaagcgaa tttaagaaag cggaatacat 64441 acccgtttac gaatacggtg taaaagttgc aggcatagaa cctgagggaa cagttgttca 64501 gccttcccca agtcctactc ctactccaac accgcctcat tcggacgatg tcctgtatgg 64561 agacataaac aatgataaga cagtaaactc aacagatgtc acatacttaa aaaggttttt 64621 actgaaacaa ataaacagtc ttcccaatca aaaagcagcg gatgtaaacc tggacggcaa 64681 tataaattct acagaccttg ttattttgaa aagatacgtt ctgcgtggaa ttagcaaact 64741 gccttacgca ccttaacgca tactttaaaa cagcaaagaa gcagtaaaga aatcaataaa 64801 ggaaaaattt ttaagtaata attaatacaa gtaattatta aaattcgcac cacaaataaa 64861 aaactcaggg acaaaaagtc cctgggtttt ttatttacgt tcacgttcta ttaatcttct 64921 ttactcaacg ccttttttat cattttcgcc atgccggtgc aaggatttgc aactccgatt 64981 tttttaccgt tttgctcacc acctgcggca ttcagaccga caacttcacc cttcgaattc 65041 agaattggtg ctccacttgt tgcagttaac tctatatcct tttcctcata ttcaaaaacc 65101 aacattttgt ttgaagcaga cttaaccttt gctttatgta atctgggctc cacactaagt 65161 attgtgggcg ctgcaagcca aaccgtttcg ccttttttag gaagctttga acttagtttt 65221 aaccggttgg cattaagatt ctcaccataa taaaaagcaa cgatatcttt attaacttcc 65281 ggatatgtat cagcatcctc aatttttaaa attttttcac attccccgca ctcactgtcg 65341 ttatatgcat ccgtaaatac aactttttca aaaacatccg gcagaaccga agcaggaatt 65401 tgctcatcca aacctccgga ttctccaaac aagtgataag cagttaaaac taaagacaca 65461 ctttcctctt ccagctctac agcaaaagca gtaccggcac tgaaagtcac atccttcaac 65521 ttaaactcgg gtcttaaaat tgtattatcg ggaagaacag gcggtatatc ttcattgaca 65581 gtcgatgtaa aatcatctga cgccgagcag gatgtcagca gcagaataga aataattaaa 65641 aaaaagcaat tataaatttt ttatttttca tatactacct ccactaccca tttttaataa 65701 acatacagta aaaattatat tttaaaaaca agcacgatat gctttccgtc tactttcccc 65761 cggtaaaaca gaaagcatat cgtgactttc cactaaaaaa aatgtaaatt caaccgacaa 65821 ttttgagcac ttcaggatac caaaccgata ctaagcttct aaaaaatctt aagctttccg 65881 ttgtaaatta acgcaacgat gctttcaatt cattccattt gtcattgtag taaaccgtca 65941 tctccggacc aagatccaca aacacttcac acttgtctat aatttcctgt ggagggtaag 66001 ccgcaggatt gttttttatt tcttcatcca acatgtctct ggcttccgta tgcggtgtgg 66061 aatatccaac atacttggta ttgttgtaag caatctgagg atcattcata aaattgataa 66121 aagcttctgc tgcttctttg ttttggcaag tctttggtat aaccatggcg tcaacaaaga 66181 agtttgtacc ttcctttgga actgcatatt ccaaattctc gttgtattca gaagtataaa 66241 cagcttctcc ggaataaatt accgccaaag ccgcctcttc ccctatcatc ttgtccttta 66301 cctggtccat caggtaagcc tgaaccaacg gagcctgctc tatcaggctt gccactgctt 66361 catccacctg cgctttgtca gtgctgttca gggaatatcc caaccttttg agggcaacag 66421 caaaagtgtc tcttaccgaa tccatcatta taatttgacc cttgtacttg ctgtcccaca 66481 gaatatccca ggagtcaact tcctcctgca ccattttttt gttgtaaaga attccgagag 66541 ttccccagaa atatggcaca gaatacttgt tttccgggtc ataacccaaa tttctgaatg 66601 attcgtcaat atattttgca ttgggaatat tgtcaaaatt caaaggcaac agttcatttt 66661 ccgcaatcaa tttctcaatc atataatcgg acggaatcaa aacatcgtaa tttaccgcac 66721 cggatttata tttagcatac atggtttcat tggaatcaaa agtttcataa ataaccttaa 66781 tgcccgtttc cttggtaaaa cgttcaatag tatcttcagc tatataatct ccccagttat 66841 agacataaat agtcgtaccc gcaagaggtt tgctggggtc atttttaaca ttgccggcac 66901 agcctgtaaa tacaaacatc aacacagcca atagcaacgc aatttttttc atacatttac 66961 tcctcccaat tttttattat ttttttcaga gcgtttattt attattaaca gcaatatcaa 67021 tatagacaaa aacatcacag ttgataccgc attgatttcc ggtttgatac cgcgccgtgt 67081 cattgtatat attgtaattg aaagattggt cactccgctg ccggttgtaa agtaacttat 67141 tataaaatca tccaaagaca aagtaaaagc caataaaaat cctgtgataa tgttgggcat 67201 aatctccgga ataataacct tccagattgc ctgcatcgga tgcgcgccca aatccagcgc 67261 agcctcatat gtgtatttgt tcagggaact taactttggc aaaatattca atatcacata 67321 gggaatgtta aacgttatat gggcaatcaa cattgaagta aatccaagct ttaagccgat 67381 tgccacaaaa aacagcataa aagcaattcc cgtaacaatg tccggattca aaaccggcag 67441 gtatgtgacg tttaaaacca ccgttttggt cttctttttc ataacatgga taccgatggc 67501 cgccaacgta cctataacag tcgatataac tgccgccagc aacgctatca gcaaagtata 67561 gtaaatggat ttggaaatca tggggtcatt cagcatgttc ttataccatt tcaaagtaaa 67621 gccgccccat ttggctcttg attttgagtc gttgaaagaa aacactatca acgtcagtat 67681 cggtgcatac aggaaaagca taatcaatcc caaataaagc ttttctatac ctctttttac 67741 catagtcccg caccaccttc catatcttcg tcacttctct gcataacagc catcgagatt 67801 aaaatcataa tcatcaacac aagagaaaga gccgctccaa atccccagtc atacgtcagc 67861 aaaaactgct gctcaattat atttccaatc aagttgactt ttccgttgcc caacaaattc 67921 ggaatgacaa aggatgtcac cgccggcatg aacaccatgg ttataccgct cattactcct 67981 ggcatgctaa gcggaatggt cactctcaac aacctctgaa aatcattggc acccaaatca 68041 tatgccgctt ccataacaga cttgtctatt tttgccagcg aattataaat gggcaatacc 68101 ataaagggta aaaagttgta aaccatccca agtacaatag cacttggcgt tccaataata 68161 tctaaaacag gcaaatggag agcccgtaaa aacgtattta aaagcccgtt gttagtctca 68221 agcaatgaca gccatgcata agttctaagc aaaaagttca tccacatggg caaaataaaa 68281 ataaacaatg ttacagagcc acccttgctg tgttttgcca aaatcaatgc caaaggataa 68341 gccaaaacca ggcagataac cgtggctata aacgcatata aaagggattt ccacagcgct 68401 atcaggtatt tgctgtcaaa agcctttatc agatgttcaa aagtaaatct taatccgccc 68461 gcatcttttg ccgtaaaagc ataataaaaa atcattacca gcggaaccac aataaaaata 68521 accatccaca ccagataagg ggcagccaac cattttctgt tcatgtccct gcctccttct 68581 ccatcttctt cataatatga atatcaaaag gatccacatt gatacttaca ttttcaccgg 68641 gcgtaaagct tttagtattg tgaataaccc attcaaagcc atccgtcatg acacaggttt 68701 cataatgaac tcctttaaaa atacaggacg ttacctgacc gtttatttta ttttctgaag 68761 gctcaagcag ctttatatct tcgggcctta tcacaacatc cactttttca ttgacggcaa 68821 atcccttgtc cacacattca taaacacggc cgaaaatctc aacaacccca tcctgtctca 68881 ttataccttc cacaatgttg ctctcaccta taaagtccgc aacaaaagca ttaaccggct 68941 cattgtaaat atcttcaggt gtacccttct gctgaataac accgttgttc ataaccacaa 69001 ccgtatcact cattgtgaga gcctcttcct ggtcatgggt cacataaaca aaagtaattc 69061 ccagttcttt ttgaagagtc ttcagttcat actgcatttc ctgacgtaat ttcaaatcca 69121 gtgcacccag aggttcatcc agcaaaagaa tttccggctc attaacaatt gccctggcaa 69181 ttgcaaccct ttgctgttgg ccgccggaga gctgatcaat ccgtctattc tcgtatccaa 69241 ccaagttcac ttgtcttaaa gctttttcca ctttttcttt aatcaagctt ttgttcatct 69301 tttttatttt cagaccaaaa gctatgttct cataaacatt caaatgtgga aaaagagcat 69361 acttttgaaa cacagtatta acgtttctct tgtaaggcgg tagattactg atgtcattac 69421 catgatgcag aataattcct tcatcaggtt tttcaaatcc tcctataagt cttaaggttg 69481 tggttttacc acaaccactt gggccaagga gggtaaggaa ttcgttcttc cttacgtcca 69541 aagtcaggtt tttcaaaacc acctgatcat caaaactctt cgtaacattt tccaatctta 69601 taacaacatt cctctccacg gcaacctcct aaaaagttgg gggcgtactg acccaaatga 69661 cttgagcgtc gctttctccc acatttacta tataatgttt tcttgttgat tcaaaataga 69721 aagactctcc ttcattaacc cgataacact cattacctat gtgtacctca atgcttcctt 69781 tcaccacata gccgaattcc tctccttcat gggggtggtc ctccagcgac ctgcctccgg 69841 gctggagagt catacgtatg ggctccatcg cattcttctg tgaattaggt acaacccatt 69901 ctatggtgtt tttaagttcg ttatctgttt ttgaaaaata gtctttctct ctgaaaacaa 69961 tttgtttgtc ttcagaatca ctgaaaaaag tcttcaaatc cgtacccaga cactggagga 70021 tatcaaccag cgtattaatg gacggcgaag taaggtcgtt ttcaatctgg ctgataaagc 70081 ctttcgaaag ctccgccctg tcggccaatt cctcctgtgt catttgatta gcgattctaa 70141 gctgtcttat ttttgctcca atctgcataa atatccatcc cgtaaaaaat taagaatcat 70201 aataaaaaaa ttaagtttta ctaaaccaaa agtttactta tagtaaacat ctagatttta 70261 ttatatgacg attttttgat ttgtcaagaa aaattttttt atcataataa tgtataaaaa 70321 tcccttaaat tccccggata attccataca gtcaggtatt tttatgtagt attttgatat 70381 taattatatg ctgaaatatc aaaaatggat aaaaatatat attgtaatat atagattgta 70441 atatatgtaa gatttttact atgatttgca tgacaggaat tgcgaagaca gggtttagaa 70501 acagcacttt taaccattat tttctgcaat aattgcaatt gattcactgt tatcggtata 70561 ttccttaccg gtaaaatcag aataaatttc tttttttaag tgcgcttcca gcattccttt 70621 tgatatatgt tcatcatccc aaaacatttc ttcgcctttt tcaaacagcc ttggtttttc 70681 actgctgatg cttaacagcg ccatatccag cttaccggtg tttattaaat tcacaatttc 70741 acttcccatc taaagactac tagtaattac ataccgcttt tgcattttcc agcaactttt 70801 gacgcaaaca ataactgaat tgaaaaacta tttttccaat ttgtaaagat tattatctct 70861 tctgccaaaa tactcaacta attctttaag ttgtagataa tgagaatcta ttacaacttc 70921 caaaggttct tccaaatcca catagtattt gttaaaaact tctatcaatt tatctgcagt 70981 ctgaagaact atttttaatt tttctatttc ttcactgcct aaagccagct cctcttttcc 71041 ctccgccgtt gcttttaatt ctccaaaaaa gtttactata ggagtcatca tttgcgcaaa 71101 atttgaccaa taaaaatctg gttgattgta tatttcttta aattgctcat ttccatacac 71161 ccatgtgtaa tttacataat aagtattaaa tcccacattc agcgtatcaa atcccgtgta 71221 gagcatatca gcttccctat aagtaattga ctttctatta attatgtttt ccaactggtc 71281 tctggagtga agtatcaatc cactcatagc actaaaataa tcatatccaa gcaactgatg 71341 tgcatagtat ttatgaatgg agtaattata tgaatatttc gaccacaaaa tggtgttaaa 71401 cattaaaaac aaagcaaaca aacagctaat atgactataa tgtacctgta tacagccaat 71461 ttatccacat tattcaattt acctatcata ttattcaatt tatttatcat atcatcccct 71521 cattctacct cgggtggctc aatctcgaat tattttttaa gttcgaaaca gcaagccctc 71581 ctaaaatttc aggttctttc ccttttccgg aattagtttt ttaccaaatg ctctgtcgga 71641 atgaacattc ctcatactta ttctgttatc ttgacagtaa ttttttactt taagcagacg 71701 cttgtccatt actaaataat ttgtgaaatt ttagataatt cctttaaatt accggaaaat 71761 ctatttcaat atcccggctt ctgacaatac attctctatc ctccatggta atttaaatcc 71821 atccatttga aaaacctatc atacacttca cctttgtaat cttctgtcaa caacgttttc 71881 tctctgaaaa cttcaaccaa ttctccgtct atgtagtcct ttactaccaa tgtctgcata 71941 ccttcactat cgggatctcc catttccaaa tatctcacac aggtcaactt tccgtcaata 72001 tacttataat accgtgtttc atttgccgcg gcactactcc tccaatatcc cttgaccact 72061 tttgagttat tgtcaaattg cggtatggat atttcactta ggccaggaga ttcctcaaac 72121 ctttcagacg aaggattcca aatccaaaac ttacaataat agttagccat gcctctgtta 72181 taaacatagc aaaaatccat atatccgtcg aaattggcat cgactgtttc ataatcttta 72241 aaaagcgaat ccaatgtttt atcttctata acttgcaccg gtgaagacat atcattgacg 72301 tcataaatcg aaatattcag cacgctgtcg tagaattcat cattttctcc ctcttcaaaa 72361 ggccgtgctt ccattatcac tttaaagctg tgttttccat ccccaatatc aatagtaaat 72421 gattctttca tatcttcact ggtcggtttg ccatcatttt gactggtctt gtcttctgtt 72481 ttttcatttt cagaactgtt accattttct gttttcggtt tttcaatctt attgttaggt 72541 tcaggaattt cttttttctg atttgccgta catcctaaca atccaaaaca taaaaatata 72601 atcacaatcg ccagcttttt gatattcatt tcccgtaact cctttaaaat aatagttgag 72661 atgacattct ccattataaa aaactcttat tcaaatactt acaacataat aaaaatgtct 72721 ataattaaaa atgcattaaa aatgcataca ataaaagctt attgcaatga atatcagctt 72781 tttaacttta tgtaaagtta atgtcttaaa atcaacaatt tatttactac aaaattatat 72841 aatttattat tacaaattat taccacacaa acaagagttt tttattctat tcaactttta 72901 ataatcagta agacaaatac taaaatattt ttgagtatct tcaatacgca aaaagcggga 72961 ttctgaaaga atcccgctct atgtaacgtg ccacacgcat tacatactca aaaacttctc 73021 tatcctgttc aaaccttcaa caatattctc catggaagtt gcataagaca acctcacgtg 73081 aatatccgtt ccaaaacctg aacccggaac caaagcaaca tttgcttttt ccagcagagc 73141 ttccgcaaag ctgtcggaac cggttatttt catgccggct atttcttttc cgataagctt 73201 tgatatgttc atcattacat agaaagcacc gtttggtttt atacaggata ccccgttcat 73261 tgagtttatc ctatcaacca tgtaatctct tctcttcaca aactctgccg acatctcgtc 73321 gattatctcc tgtggtcctt caagggcagc caatgcagct ttctgtgcta ttgaatttgg 73381 atttgatgtg gcatgactct gtacattagc cataattttt gcaatttgct cgttgctggc 73441 agtatatcct attctccaac ctgtcattgc ataagatttg gacacaccgt taacaactat 73501 ggtaaggtcc ttaattttat cattaaagga tgcaatgctc acatgcttgt atccgtcata 73561 aataagcttt tcgtatattt catcggatat gatatatata cctttgctca cagccaaatc 73621 ggccacagct cttaattcct cttcactgta aatcataccc gtaggattgc tcgggctgtt 73681 gataattatt gctctggttt tgtctgtaat agctttttca agtttatcta tcgtaaattt 73741 aaagccctct tcctcggaac aatgaatgta aaccggcact ccgtctgcaa gcttaaccat 73801 ctcaggatag cttacccatg caggagtcgg aataattacc tcatcgccgg gattgcatat 73861 tgcctgcaaa gcgttaacca gagaatgctt tgcaccgttg cttattacaa tatttgaagg 73921 attgtaatca agcccgttgt ctctcttaaa cttccggcaa atagcctgtt tcagctcaag 73981 tgtacctgaa gccggagtgt atttggtaaa cccggcattt atagcatcta ttgccgcttt 74041 ttttatgtga tcaggtgtgt caaagtcggg ttcacctgca ccgaatccaa ttatatcaat 74101 tccttctgac ctcatctttt tcgcttttgc atctatagcc aacgtggaag acgggctaat 74161 agaaagcgcc ttttttgaaa ctaccatttt ataccctcca aaacaatctg atatgatatc 74221 atgtacctta ttttaatata taatattcga ttttgcaagt tattgatata aaaaatgcaa 74281 aattattttt tgacataaaa ttattactca attttataaa agatatggtt tttatgatgt 74341 cattattatc agttaaaatt ttagagatac acatcgaatt cctttccaac tataaagtat 74401 aatcattatc aaaatgcaag ttttttatat tattatttca ataacaatta ttattttatg 74461 gaataaaatc cctgaaaatc ttatgcatta aagaaaacat aacggacaaa ataaataacg 74521 caaagggttc gtgatggtcg agccaagagt gttataaggt cattatattg gctttataac 74581 attcggccaa agattaatat caggtttcgt ccagggttga cgccaaggct tgatattagt 74641 cggcgggaag agtcttgaat atctgaaatt ttggatgttc ggattcgagc taagattatt 74701 attattgctt tattgcaaca aattgtctcg tagccaggtt ggtttcgtta tggcaattgc 74761 tgtaaagcaa tgataatagt cgaacaaagg tctgtataaa ttcctttgat ttagagttta 74821 gaaatttata caggccggcg tgaagatcat cacgggctct ttgttacata gtgttacata 74881 ccataaaaaa cacatactat aaaacatttg attacagaac attttgaatt accctgagaa 74941 agttctttcc ggcaaatttt tctatatttt cactggaata atttaatttt gcaagctcat 75001 taaatatctt ttcaatatcc tgtactccat ttattcctgc cggcaaaccg tcaacaccgt 75061 caaaatcagc tccaagccca atatggtcag gaccggcaag gcttgctatg tactcaatat 75121 gattgataat atcctttatc gtagcttcct tggagttgtt taaaaattcc ggatacaggt 75181 ttattccaat tactccgcca ttatctttta cggccattat ctgtttgtct gtgaggttcc 75241 tcctgtgcgc acaaagcctt tgggcatttg aatgggatac aatgaccgga gccgaagtac 75301 actccaatac atcccaaaag cccgtttttg atatatggga aaggtcaata agcattccca 75361 gccggttcat ttcttttacc acttctcttc caaaaggcgt aaggccgcct cccgaagatt 75421 cgtctttgac cccgtcggct atttcattgc ggtgattcca tgtcaggcaa atgctcctta 75481 caccaagtct gtaaagcatc cttaaaacac caaggtctcc ctgcagggcc tcaccgcctt 75541 ctattgaaag cactgcagca atcttattag cctttacagc ctcttcaata tcattgtaat 75601 tacaacatat cataatgtcg tctttattaa cttcaatctg tctgtaaaac tcatcaatta 75661 tctgcaaagc tctttttaat gcgtatgcct gacagtaagc agggtctata aatgctgcaa 75721 aaaactgaac atagtttcct tttgctttaa gcctatctat gtcaacatgg cagtcattct 75781 tacgaagttg tgtacccttc tccattattt ttgttattgt atcacagtgt gcatcaacta 75841 taatcatgat tccactcccc aaaagcgctt attaaaattc cataattaaa accaattcaa 75901 aagcttttcc ggcctctgtt ttcctgcacg tacaaaacct ttatttatta tatttctaat 75961 gtatgtttat taataaataa ttatgtttat aatgccccgg tttaaagaaa atttttcata 76021 tcaaccggaa agcaggcctt tttcggcaaa acttacatat tgtcccccgc agacaattat 76081 gtggtcaacc acctttatag agatggcttc aagagccgct ttgattcttt tggttgcttc 76141 aatatccgct ttcgacggat ttaaagttcc gccgggatga ttatgtgcca aaatcacact 76201 gttggccttg tggcgcagtg cagtttcaac aattattcta ggatacaccg gcgcttcgtt 76261 tatcgtccct tcatgaacca gttcggcata atttacccta ttttgtgcat caagacaaat 76321 aacataaaaa acttcataat ttcttcccgc aaaaagcgaa atggcatatt gtccggcttt 76381 tgccgaactg ttgagctcgg gcttgtccct ccacttatca ttaagataac gccttgaaag 76441 atggggtatc agtgacagca atattgcaga attttctccg attcccggcg tagttgccaa 76501 atcttttggg tctgcttcaa acacaccgga caaagaacca tacctgttta gaagtgtgtg 76561 agccaattca ttggtatctt ttcttggaat tgaaaaaaac aaaagcagtt ccagcacctg 76621 atgctgctca aaactgtcaa gtccttccct taaaaatctt tctttaagtc tctttctgtg 76681 accttcatgc accaagcgaa tattccccct aatacgagat aaaaccagat tataaataaa 76741 ataaagcctt ataaaataac cctaataatc caacaaaaca aagttctata gcaaacttta 76801 tatcttaagc taattttata tcttaaaact attttaaaag gcattcttaa tcaaggaaat 76861 ctcttttact tcaatgtcgt cgcctttttt ctccatataa acttccacca catcaaacct 76921 tacttttaaa tcatttatcc ggtttttaca aagatatatc tgggcaagtc ttctgatatt 76981 ctcctgtttt cttatattca cagcctccct tggatagccg tatccaagag agcttcttgc 77041 cttgacctca acaaaacaaa tataatcctt ttcccgggaa attatgtcta tttcacccag 77101 tcttctgtat cgaaagtttg tttccaaaat ctcataattg ttttctttca aaaattgaac 77161 agccgcagct tctccaattg accctgcagc tcttttgtta tttttgttac ctactttgct 77221 gttcatcttt ctctccactt ttatcttttc ttttctccat attttttatc aacgctgccg 77281 acaaacacca gaatctgggc cacaatatca taaagttccg gcggaatttc atctccaatg 77341 ttcatggcat ttaaagcagc ggcaagctct tcattctcat atatgggaat gttgttttcc 77401 tttgcctttt caagtatttt ctccgcgatc tcaccttttc ccaatcctat gatttgagga 77461 gcattgtttt cctcaggtga atattttaaa gctgccacct gctttatttt tttcctgcca 77521 gacataaaac ttcccccgtc aatcaaattt tgcagtcaaa ccctctgttt cttgttcttt 77581 ctatttcttt ttccaaaacc tcccgggcat ttaacagatt taccttttca tctataagcc 77641 tgtatttgat atccacaagt ttatagcctt ttttggccaa tccttcataa agctgaatat 77701 agttttcttt gatataatct atgatttcat ttttttcaag cctaaaattg aggctgacat 77761 tctttttgtt tacactgata agagagtcca cttgtcccaa attttccgta tccaatgaca 77821 aaaacacagt ggcattttgc ggatcaattc tttttcttcc gttgtttctt ttcaatatat 77881 aaagctcacc gttagtattc ttgtcaaata ttttcagagg tatctgaaaa tatacggtat 77941 gtttgtttaa ctcatttaaa aaatttatat cgctcttaat gttgtcaact ttgtttaaaa 78001 tctcttgttt acctgggatg tcggtctctt ctaaaacttt gcggactatt tcaagctttt 78061 tataaatatc tctgtaaaat tcctttacat taatatctct gccttcaact tcctcattaa 78121 tttttgcaaa catcttttca aaggattttt ttataacttg agccacatta ttagtttcag 78181 aacggccttt gccggcgctt ctgcttcctt gtgaagccag aatcacattt aaaaagtccg 78241 caagctcttt ttcagatttc tctatgtttt ctttgtaatt aacaaaatca gcagtttttt 78301 tctttaattg taatatctca tttccctcta tgtcaacatt tttcactgtt ttatccaaat 78361 tttctgtacc tatattgcca tttcgggaca attcaggctt acggctccaa tgctcctttt 78421 cacttttttg agccacattc ccttcaatat gccaattctt ttggctgtta taaatttttc 78481 cgttttcata atgaataggg gaagtgctga catcagaagt ttctccgctc ttttgagaag 78541 gataatccat ggcattaagc ttttttaaga tggcaaaagc cacatcttta tcctgaatct 78601 ctgcaagact tgaagccaga tctaaaagct cagaactcaa tctcactctg ccctcgacaa 78661 atctatttag acttgttata cttttttctt cgggaataat attgtttgaa acaagatagg 78721 ctgcttttgc aatgccaagg tttttaaacc taagcaccgc atcaacaact ttggtaatgt 78781 tttcagcatt aagctgagtt ccattggcac gaagttcagc cgccgtctcc atatttcttc 78841 tgtcaggctt tatgccaagc tgtgcaagct tgtttttaat ttcgtcctca acattgggct 78901 gagcggcatt ttgaacgcca tccttcatga tttccaaaaa caattgattg ttcactttgt 78961 tttttacaat aaaatcaagc aactctccct ttttggcatc tatgggagtc atagtaccgg 79021 catttatcaa tgttccgtca aacagcttta ggagcagctc atttgcagta atgtcaacta 79081 cccttgctct caaggtatct cccgtatcaa gccgcgaaag tatgtccaaa gctccggtct 79141 gttgaattaa tacattttcc gagctttcta ttctcacttt tcttcctcct aaagcatttt 79201 gtgaaaagcc tggcctatac tatgaagttc tttgtaaagc ttactctatg tatcggacaa 79261 ataccgtatt tcttaatagc ttctatatgt tcgccggtac cgtaaccttt atgcctggca 79321 aatccataca ttgggtattt tttatccatt tctcttagta tacggtccct tgtaaccttt 79381 gctataattg acgccgccgc aatggacacg ctttttgcat cgccttttac tatggaattt 79441 tgttcaatat ttatatcgtc aagttttaaa gaatcaataa aaagaatgtc cgggacaggc 79501 tttagattgc caacagccag tttcattgct tttttcgtgg cattcagaat atttatttca 79561 tcaatttgct tttcatccac aatccctatg cccactccga tcgctttatc attaattacg 79621 tcaaaaagct tttccctttg attctcagtt agcttttttg aatcattaag gccttctatg 79681 aaaacatcct ggggaaggat aaccgcagca gctacaacgg gacctgcaag tgggccgcgc 79741 cccgcctcat caatcccggc aatcaatttg tagcctctct gataagcctc tttttcatat 79801 atgcacattt ccaggtatct attcagttct ttttcatatt taagtttttt cttttcatac 79861 ttttctatga ttttgtcaac cctgtctcca aactcagcct taaggcaata aagcttttcc 79921 aaagccttat ccaggtccaa accttccacg gacttctcaa tttgtttgac agtcatattt 79981 cccatcttct tctgcaccat cactttccgg caatatcata aaacatatct taaaacatat 80041 atcaaaacat atatcaaagc gtcacaatcc gagattttcg cccacaagaa ttactttaat 80101 ccttccggga acaatgctgc tgtgcatttc aacaatctga gcgcaaatac ttgacgggtt 80161 attcttattg caatcaaaac agcatcccgt tttggtgcag ggaagctcca gacccaaacg 80221 cagtgcgtta ttcggggctg cataagtatg tgcccgtttt cttgcactct caaggtccct 80281 gcatattttg ttcataccga cgacaagtat taccgtttta ggtccaaatg ctattgctga 80341 aatacgattt ccccttccgt cgatatttac cattattcca tcctcactca tcgcattcac 80401 gctcgccaaa tacacatcgc tgagcagcgc ctgacgcatc agggaaaaac gctcttcctg 80461 agattttgca gtatcccggt caattacctg ataatttccc tcttttagcc tctgtatcaa 80521 tccgatttcc tcaagagtca tggaaccgcc ccatgccacc gatgctcctt gaggaattaa 80581 ggacagcgca cactcaaccg ccttttcgga agtctcacag aaataagctt caaaatttcg 80641 ctgattcaag gcttttatta ttcttggagc catcacctta tatctttcac gaatgatttc 80701 ttcacttttt gccatgttaa acacctccgt cacgttaatc tgctactaat tcctgtacag 80761 catctcccgg tctttccagg gtaatccttc ctattttgcc tccgcggaac tcatccagta 80821 caatagctgc aatccttgta agatccactt cgcctccgga aattatgcag cctctctttt 80881 tgcccgcttc ctccaaaagt tcatatccct ttttgtcctg cagcgattca agcttgtatc 80941 ttttcttaat attctccgga taagtttttg aaagatgctc aagcaaaatc gaagccagtt 81001 ccacggtatc tattatttca tcttttatcg cgccggtaac ggccagattt atgccaaccg 81061 tcttatcttc aaatttcggc cagaggattc ccggcgtatc catcaactga atttcattat 81121 tgacatttat ccactgtttg ttgcgtgtaa caccgggcct gtcgccggtc acagcactct 81181 ttttgccggc aatcttgttt ataagagaag actttcccac attgggtatg ccgacaatca 81241 tggtccttat aggcctgaaa attctgcctc tttgcctgtc tctttcaatc ctgtccttca 81301 taatgtcccg catttggtct ttgagctgct ttattccggt accttttatg gaatcaataa 81361 aaatagtggc ataaccttga gaattgtacc atttgctcca ctcgttcgaa atcttttcat 81421 ccgccagatc ggctttattc agcaccacaa ttttcggctt gttctttaca ataccgtcta 81481 tctcaggatt tttactgctt gccggaattc ttgcatccaa aagttcaaca accacatcaa 81541 ccattttcaa attttctgca agaatccttc tggtcttggc catatgaccc ggaaaccact 81601 gaatattcat ttgttcctcc caaatccaac ataatcaata aatactgcca aaacttttca 81661 aaggctttac tctaaaaatt gcttttccct ttatacgttc aaaaccgata aagcccaatt 81721 gcctgctgtc tttgctatat tctctattat cacccatgac aaatacttta ttctcaggca 81781 ctactctggg aagctcaaag ctttgctcgt aagttaaccc ttttgtatac ggctcttgtt 81841 gcttttcacc gttaatgtat aaatatccgt ccctgatatc aatctcatct ccgggaagtc 81901 ctaccaccct ttttatgtag tttacctcgc cctggctggg aaaaagcgtc ctgaataaag 81961 gtatatcttt aaaaaaggct aaataatccc aattcccttc ataaatctga attatgacaa 82021 tgtcgcctct tttcggcctg tcataattga gtttgcttac aaacaaaacc tcgttgttgt 82081 aaagagtgtt ttccatggac tgtccctgga caaccaccca ttcaaacaca taggctctaa 82141 gcaaaagagc ggtaaataaa gctacaacta taagtaaaat ccattttaca atttccttga 82201 aatacttcgg cttttccgcc tgaaaattgg ttccaaactt ctttttcagc tcattctcat 82261 gatttttgtc aataccggca ggtttctttt taaactccat attatgcaac ccttaaaaat 82321 tctcagattc taatgatagt atttattata tcactatttt ccctcggagg aaagaacggc 82381 aagaacaaac taagcaaggc attttgaatt gcgaaataaa ggggacttgc aagtcccctt 82441 tatttttaac tattttactc caattttgtt ttaacttttg ctgatttacc aactctctca 82501 cgcagataat aaagcttcgc tcttctgact ttaccttttc tgataacttc aataccagca 82561 actcttggtg aatgaacagg gaaaattctt tccactccaa ctccgtagga tattctcctt 82621 acggtaaatg tttcacttat tccggagcct tttttggcaa ttacagtacc ttcaaaagcc 82681 tgaattcttt ccctgttacc ttctttaact tttacgttaa ctcttacata atctccaatt 82741 gaaaaatcag gtacgtcttt cttaagctgc tcctgttcaa tagcttttat tatgtccatt 82801 cctatcctcc tccctcgcag acgttcttgt ataaaacagc ggaccgtccg tattccacag 82861 gatgacatta taccatagac ttaatatatt gtaaatattt ttttgccatt ttatttatat 82921 ttacgaaaat ttaatattta atttaatgct tactccgaag tctctttcaa cgcttcttcc 82981 agaagtttct tgtccgtctc atccaaagag agcctggcaa acaaatcagg ccgttttaaa 83041 taggtcctct ttaacgactg ctgccttctc cacctgttta tgttttcatg atgtcctgac 83101 atcagcacgt caggaacttt tctgttgcaa aattcataag gccttgtgta ttgaggatac 83161 tccaaaagtc cttcataatg ggactcttga gagtaggatt cctcactgga caaaactccc 83221 ggaataagcc tgctgacaga gtctataagt accatggccg gaagctcccc gcctgtcagc 83281 acataatctc ctatggaaat ctcatcgtcc actatttctt ctataatccg ctcatcaaca 83341 ccttcatagt gaccacagag caaaatcaaa tggttctcct ttgaaagctc tttgacaatt 83401 tgctgattta gcactcttcc ctgcgggctt aggtaaataa cccttggctt gtaggaaagc 83461 ttttctgcaa tggataaata agcgtcataa atcggctggg ccatcatcac catgccaccc 83521 ccgccgccat aaggatagtc atccactttc ctgtgcttgt tcgtagaaaa atctcttata 83581 tttatagtgt taatttgtat tatattgttt ttccgggctc tgcctataat gctttcgcca 83641 agcacggcat caaaaacctc gggaaaaagt gtcaacacat caaacctcat catcaatcaa 83701 tccttgaggc aaatctacca ccattttatt gtcttcaaaa caaactttct ttaccacaga 83761 ttttagtgca ggtattaaaa tttccttatt attatcactt tttaccacat acacatcatt 83821 gcttccggta ctcagcacat cggtaagtac ccctaatttc ttttcttctg tgtcaaacac 83881 attcatacca atgaggtcac aaataaaaaa tgtgtccttt ggaagcttta cagcatcttt 83941 tctgtcaata attacaaaat gttctttaag tttttcggca gcattcatat catctattcc 84001 actgaacttt aaaattacaa agttcttgtg atgttttaca gatacaatat caaattttgg 84061 catttcattg gatatttctt tggacacata ggcccactta agtttgttaa atctacgggg 84121 attgtcagta agcggaatag ctttgacctc tccctttata ccatgagtat ttactatttt 84181 tcctacttgc aaatattgta tcaccggtct tacaccacca tctaaatctc ttaatccagc 84241 tggattttac caaaagcttg gccatcaact ccaacaagct aaaaaatgtg gacaagagac 84301 tgacccctgc ccacattttt ttactgtaat atttccacag atactctctt gttttccttt 84361 actgctgccg ccttcatcac tgtcctgatt gccttcgcta ttcttccttg ttttccaatt 84421 accttgccca tatcatcttt tgataccttt aattcaagga taacggattt ttctccttca 84481 acctcattta cataaacatc ttccgggcag tctaccaatg ctctggcaat cgtctcgaga 84541 agttctttca ttatatatac ctcccgtatt tttaccttta atgtcactgt taattcaaat 84601 ttaagtatat ctgttgttat aattttagga tattactcca actttcttta gcaaagctct 84661 tacggtatct gtaggctgtg caccgttttt aagccacttt tgagcctttt ctgtatcaat 84721 tttaatctcg ctcggctctg taagaggatt gtaagttcct atttcctcta taaacctgcc 84781 gtcgcgagga tatctcgagt cagcaacaac aactctatag aaaggcctct tctttgctcc 84841 catccttttt aaccttatct taactgccat tttttcacct cccgcaacta taattagaac 84901 tattttttat taaaacggca ttcggaattt tttcaatccc tttttaccgc gtttacccat 84961 ttcagtcatc attttcatca tcttcttcat ttcttcaaac tcttttagaa gcttgtttac 85021 ctcctgaacg gtggtaccgc ttcctgcagc aattcttttt ctcctgctgc cgtttattat 85081 tgaaggattg ttcctttctt cctttgtcat ggattttata atagcctcga cacgggccat 85141 tttcttctca tccagttcta tatctttcat gacatttgca ttgaaccccg gaatcattgc 85201 caacagttga ttcaaaggtc ccatcttttt aatctgctgc atctgttcta aaaagtcctc 85261 cagcgtaaac tgctgggtgc gcattttctt ttcaagctcc aatgcctttt tctcatcaaa 85321 ggcttcctgg gctttttcaa tgagacttaa aacgtctccc atgccaagaa ttcttgatgc 85381 cattctgtca gggaaaaacg gctcaatatc atttaatttt tcgcccatac ctataaactt 85441 gatgggcttt cctgtaacag ctttgacaga aagcgccgct cctccacggg tatcgccgtc 85501 aagcttggta agtatgatac cgtcaacacc caatttttcg ttaaagcttt ctgcaacatt 85561 tacggcatcc tgaccggtca ttgagtctac cacaagcaga atctcctgtg gcctgacggc 85621 ttcttttatg ttctgaagct cttccataag ctcttcatta atatggagtc gaccggccgt 85681 atctattata acaagatcat actgtcttga tttcgcatat tcaacagccg ctttggctat 85741 gtcaacggga ttggtcttgt ctcccatcga aaatacttca atccccagtt gtgaaccaac 85801 cacctgcagc tgctttatag cagccggcct gtatacgtcg caggcaacca aaagaggctt 85861 tttgccctgc tttctcaaaa ggtttgccag ttttcccgac gtggtggtct taccggaacc 85921 ttgaagtcct accatcatat atatcgtagg tggttttgat gaaaatgtta ccttgctgtt 85981 tgcagaaccc atgaggttga taagctcttc atggacaatt tttataacct gctgtccggg 86041 cgtaaggctt tccaaaactt cctgccccac ggctctttcg gacacttttc caataaagtc 86101 cttgacaact ttaaagttaa cgtccgcctc caaaagcgca agctttatct cgcgcatcat 86161 ttcttttacg tctttttcag taactcttcc tttgcctctg agcttcttca ttgcctcctg 86221 aagcttgcct gacaatcctt caaacaacat aatactatgt gacacctcaa ttccataagg 86281 atatcgaata ctcagctttc cacaatttcc tctattctct cttcaactct ctttaaaatt 86341 ttcgcatctt caacactcat gctgctaata tcaatacttt ttatatcctt tagtatttcc 86401 aatgctctgt ttttctgctg caaaaattta tgcacaagtc cgagtttttc ttccatacgg 86461 tccagcatag ctctaccgcg ctttatattg tcataaacac cctgcctgct tatattaagg 86521 tgctctgcaa tctcacccaa agaataatca ttattcaaat aaagatccaa tatttcaaac 86581 tgcctttttg taagcagctg tccgtaaaag tccagcaaaa gcgcagcttc atacacctta 86641 tccatatgtt cacctgtaaa gtaaaaatac tttacacaca attttaagct atattttgca 86701 attagtcaag cttttttaaa aaaataataa tctgtaaaag aaaaaagtac cctttttcat 86761 tgaaaagagt actttaaagc aatatccggc tttaaaacaa catcaagctt aaaaaatatt 86821 aaacccactt ttaaagccgg taacatttta tatcaaaacc acttgtcaaa actactcgac 86881 aatcacctta agttccattc cttcaattat ctcacagtct tcaagattgt ttaaaatcat 86941 aatatcatat atgtattttc tgatatcccc gcgcttattg tagttttcgg ctatgctcca 87001 cagggtatcc cctcttttta ccgtaatcgc ctcatatgaa ggctcccggt atccatagat 87061 actcgtggct cggcttataa cagccgtcaa acccatcagc acaaaaagaa caaatacaaa 87121 aaatcttctt ttattcttta aaacatattt ctttttcata aaaaatccct caccgaacta 87181 atgttctata ccgatattat aaacgaacac acgttcttgt gtcaatataa attaaaaaaa 87241 atatcgaaca ttagtttgat ttgttccaag attaatgata taatactgtc aagcaagtat 87301 taacattatt agcatgaggt tttaccagca gcataaaaat gtatccgagg tgaaaagaat 87361 gcaaaataaa ataaacgaaa agcagcaaaa aatccttgat tttttgaacg aacagataga 87421 aaagaacgga tatccacctt ctgttcgaga aatatgcaat gccgttggtt tcaaatccac 87481 gtccaccgtg cacagctatc tggagaaatt gagaaaacaa ggacttatcc aaaaagaccc 87541 ttcaaagccg agagccctta aagttattaa taataaaaag aattccaaaa cagatgaacc 87601 taagaacata tattccggaa aggagcttgt tgaagtcccc attattggaa aggtaactgc 87661 gggtcagccc atacttgcag ttgaaaatat tgaagatact tttccgctcc ctttggattt 87721 tgtccaaaat tcaacggttt tcatgctccg cgtccagggt gacagcatga tagaagcagg 87781 tatttttgat aatgactata ttgttgtaaa acagcagtcg acggcaaaca acggtgacat 87841 agtcgtagca cttatcgatg atgaggccac ggttaaaacc ttttacaagg aaaaggggtt 87901 catcaggctg cagccggcaa acaaattcta cgaccctatt atagtaagag acaatttgtc 87961 cattttagga aaagtcattg gggttttcag gaaaatgtaa aagagttatt aaaagattcg 88021 ctgcgaaatt caacaggaaa gttcaatata aagacaaaag ctcccttaag cgcaatgctt 88081 tggagctttt gcctatttat tatcatttat tgtatagttg ttaacacctt attccgatct 88141 gttattgtcg ttgaaaatca agctaacaat tttcatgggg cttattgttg aaattgcatg 88201 tttataaatc agctgctgcc ttccctcact gtcaagcaca acggtaaaat tgtcaaatcc 88261 ctttaccgtt ccttttaact ggaatccgtt ggtaagataa acagtaaccg gaatatgttc 88321 ttttcttacc tggtttagaa aaacgtcctg taaattaata ttatttttgc tcaccactca 88381 taatcctcct ctatttctct cttttttatc tttatataaa acatttattg cgtacaaatt 88441 taccttaaaa ttttattaac aaatttattt tgttattctt attctacaag aaaataccaa 88501 acgttgcaag ataatattta agatttttta ttattttctc atcactgtca aactcatctt 88561 tgtttatcca gtaaacattt tcaattttcc taaaccacgt catctggcgt ttggcatatc 88621 gccttgtatc tctctttaaa atttcaactg cctcatcaag gcttctctct cctcttaagt 88681 aagataatat ttccttgtac ccgagccctt gcatggcaat cgtactttta tcatatccca 88741 tttcaacaag tttctcaacc tctttgacaa gtcctttttc aagcatcaaa tccactcttt 88801 tgttgattcg gtcatatagc ttttctctgt ccattgtaat accgattaat ataaaattgt 88861 gcctgggagg attctttctc gactcctcct gatgaacgga aataggcttc tttgtgtaag 88921 tatacacttc tattgcccgt attacccttt ttacattgtt catatgtatt ttttccgctg 88981 ctttagggtc aatctcttta agcttgttgt gaagatattc gttgcctttt tcttttgctt 89041 cctgttcaag tttctttcta agctcccaat cacaaatagt atcggaaaat tcaagattat 89101 atattagtga attaatataa agtcctgttc ctccggcaac tatgggaagc ttgcccttgc 89161 ttaaaatttc gtcaatatat tttaaagcaa gctctttaaa ccttgcaacg ctaaactctt 89221 catccggcgt cacttcatct ataagatagt gctttatacc ttctttttct tcttcgtcgg 89281 tttttgccgt acctatgtcc atatatttgt aaatctgcat ggaatccgca gaaattatct 89341 caccgtttgc acgcttggct atctctatgg caagcttcgt ctttcccgaa gctgtcggac 89401 cgattatcac aagtacgttg tccacttcat cctccaaaca gattaaacta ttcttttaaa 89461 cattttttca aattcatatt ttgtaatctt aacaacagtc ggtcgcccgt gaggacaagt 89521 atatggattt tgaagcatgt tgagcttgtc caaaatggct tttatttcga tttcatcaag 89581 tttcttgttt gcttttaccg ccgacttgca tgctatctgg tataatgcat cttcctcaat 89641 aattttatca tatttcctgc cctttgacat taaaaaatcc acaacttcca aaaaggcttc 89701 tttaacgccg acaccctcgt ccgggatcgg caccgaacga agtataatag aattattgcc 89761 aaagctttcg aaaataaaac ctaatttatt aaataattct ttttcttctt caagaaaaac 89821 aatttcctgg tttgtaagct ctataaccac aggtgtcaaa aggtactgcg cgagactctc 89881 atttctcgca tacttttctt tgagctcttc aaaacgtatt ctttcatggg ccgcatgctg 89941 atcaataatt atcaggtcat cttcgttctg aagcagaata tatgttgaga aaacctgtcc 90001 gattattctg gcatcaagaa atacatttcg ttcaatatcc tgctgcggcc gggtatcttt 90061 accgtcacgg attttctcaa aattcgtatc agcattatta tcgacatcat tacgattatc 90121 tttaggctta tcgctgacat cttttaaaat attatcataa ccgcttttgt caaaattata 90181 acactcttcg ccagtgccct ttaaagctgt gccatcagat ttttcaatca gcttgtcatt 90241 agtcttgtta attggctcat taattgccca attaaccaag ccactgattt gcccgttaat 90301 caaattatca accgactcgt ttttaacttc gtttacatta accttattta caacttcacc 90361 tttatttata actttatctt tatttataac tttgtcttta tttataactt catctttatt 90421 tataacttca tcttcactta taactttatt tttatctcca acttcatttt tgtttataac 90481 ttcatctata gattcatctt ttcgtttatt aatattggcg ctctctttaa caattaaatt 90541 ttcccacgtg cttttagacg tattggtctt ttcagtttta aaatcttcat cataattgta 90601 tcctgaaaac ttcctgtccg tatccagcct ctgctgcaca tagtcggctt ccttttttga 90661 agactgctca aatttgaaat aattcttcgg actgtcttta agggaaacat ttcttatatg 90721 ggttttactg agcagagcat tgtttacggc gtggtaaacg gctctgaata tctcctgttc 90781 cctcgaaaac cttacctcca tttttgtagg atgcacattg acatccacca acagcggatt 90841 taattctata tacagcacaa taaaagcaaa tttgtttttc ataagatatg ttttatatgc 90901 ttcgtcaatc gccgaagata taaccttgtt ttttatatat cttttgttta aatatatgga 90961 ctgataattc ctgtttgctc ttgctatttc aggacttcca gcatatccgg ttatctttac 91021 ggtctcatcc tcataggaaa tctccatgca ttcttttgca gtctcttttc cgtacaaact 91081 gtatatggta ctcaaaagat cgttattgcc cggggtatga ataacagtgt ttttgttgtt 91141 gattagtctg aaggaaatat cgggatttcc aagagcaatt ctgcttacta tatcggaaac 91201 atatccagcc tcggtggaat cctttttcaa aaatttaaat ctggcaggag tgttgtaaaa 91261 aagatctctt actataaatg ttgtaccggc aggacatcct acctggccgg actctaaaac 91321 agttccgccc tggattttta cataccttcc gtactccctg tgggccggtc ttgaagttac 91381 ctcaacggtg gaaacagagg caatactggc aagagcctca cctctaaatc caagggaggt 91441 aatcgcctca aggtcacttg cccttcttat cttgctggta gcatgtcttt caaaggcaat 91501 ttcaatatcg tcctcttcga ttccgcttcc gttgtcaacc acctttataa aagatattcc 91561 gccattgttt atttccaccg atatattggt acttccggca tcaatagagt tttcaacaag 91621 ctcttttacc acggaagccg gcctttccac cacttctccg gccgcaatct gatttgccgt 91681 attttcatcg agtataatga ttctccccat aacaaataac ctttctatag ttaaaattga 91741 caaccctttt aaattgcctt taagttacct caactttttc taccctttta cctttttttg 91801 aagattgtat aatacattta ttgcatcaag cggtgtcaaa gtcgtaatat caagactctt 91861 taattcattc agaacctcat cataacttct ctgggcggcg ttaaacgtaa atacgtcaat 91921 ttgcccctca atgggctgtt ttctccttgt aatacgtttt tccttcctgg ttatgtccgc 91981 atcttccaat ttttttaata tttcttttgc cctgtgaata acaggatccg gtatgcctgc 92041 aagccttgca acctgcacgc cgtagctgtt gtcggctccg cccctgagta tttttcttaa 92101 gaaaattata tcttctccct tttcctccac ggatatgcaa taattcttta ttccttcaat 92161 tctttcttcc agttcggtaa gttcatggta atgggtggca aagagcgttc ttgcccctat 92221 cttctcaccg atatactcaa ttacagccca tgcgatactc agtccgtcat aggtgcttgt 92281 acccctgcct atctcatcca ataccaacag gctttttgac gtggcattgc caaggatatt 92341 cgcaacttcg gacatttcca ccataaaggt actctggcct gctgccaggt catccgaagc 92401 gcctaccctt gtaaatatcc tgtcaactat gcctattttg gcacttttgg cgggaacaaa 92461 gcttcctatt tgggccataa gcacaatcaa cgccacctgc cgcatatatg tcgacttacc 92521 cgccatatta ggcccggtaa ttatagcaat ttggttttca tccatgtcaa gataggtatc 92581 attgggaaca aaggcttcct gcccgattat cttctctacc acaggatgcc ttccgtcttt 92641 aatttcaatt ttgtcgtcat cggtcacttc cggcatagta taggattccc tgtccgccac 92701 ttccgccagt gagcataaaa catcgattct ggcaagactt cttgccgtgg tctttaatct 92761 gtttatttct tttgcaacct tgttcctcac atccacaaat atctgatatt caagctctac 92821 aagcctgtcc tccgcaccca atacggtatt ttcaatttcc ttcagctccg gtgttatgta 92881 cctttcgcag ttcgccaagg tctgtttcct tatataatca tccggtactt gtgagtagta 92941 ggatttggtc acttcaatgt aatagccgaa aaccttgtta aatcccactt tcaaattttt 93001 aataccggtt ctttccctct ctttgctctc taaatgtgca atccacttct ttccgtcttt 93061 tgatgcgctt cttagcctgt ccacctcctc attaaaacct tcttttatga ttccgccttc 93121 tttaaccgca acaggcgggt catcgactat agccttgtca ataatttcat acacatcagt 93181 tagtgtatcc aattcattgt agcttaaaac attaagatcg gcttttaaat cacgaagaag 93241 ctcctttata tacggaacct gtccgataga gtgttttatc gatatcaaat cgcggcaatt 93301 ggcacttccc agaataacct ttgtcatcag cctctcaatg tcataaaccg ctcttaaaag 93361 ctcccgtact tcgcttctta tcataaacct ttctttaaac tcgtttaccg catcaagcct 93421 gtcctttata tcatggaggt ttataagggg ctgttcaatc cattttctca gggttcttcc 93481 gcccatggag gtcatggttc tgtccaaaac ccaaagaagg gagccttttc tgttcttttc 93541 cctcatggtc tccgtaagtt caaggtttct tctggtggcc atgtccagaa tcatgtactc 93601 ttcaatcctg tagacgttaa aattctgaat atggcttaaa ttcactttct gcgtctgctc 93661 caaatattcc aaaagagctc cggaagcatt tatgtataaa tcaaacgcat tttcttcaat 93721 cacataatcc ttaaaataat ttcttacctt ctgtatggaa aactcctttt caaaaaattt 93781 gtcctccaaa ccggagatat aaacatcaaa cctttgtttt aaagtctttt tgatgttttc 93841 gtcatgaaaa aactcaccgt ttacaacaat ttccgatggt gagaatttcg ctatttcatc 93901 cattaatttg ttgaaagtgt tgccgaaggt aatgtgtgtc gacaaaaact ctcctgtggt 93961 aagatcaaca catgcaatac cgtaatagtt tttgttttta taaatcgaca taagatagtt 94021 attctttttt tcatccaaca tagcggaatc ggtcactgta ccgggagtaa caatcctgat 94081 tacgtccctc ttgaccaatc cttttgccag cgcaggatct tcaatctgct cacatatcgc 94141 aactttataa cctttgctaa tcagtttcgc aatatatgaa tccgctgaat gaaaaggcac 94201 tccgcacatg ggagctctct cttcaaggcc gcaatctttt cccgtaagcg ttatttccag 94261 ttcccttgaa gctacttccg cgtcagagaa aaacatttca taaaagtctc ccaatctgaa 94321 aaaaaggata cagtccttgt actgctcctt tatttcaaga tactgttgca tcataggtgt 94381 caatgaagcc atcttttctt acctcacgta caagatttat tatctacaaa gatttatttc 94441 tacagccgct gcatgaactg cagtcatctg acggacaagg ctcttcgccg gaaattgaat 94501 aaaccagcac atcattaact ttttttataa gcctgtccaa tttttctttt gactcaatat 94561 aatttctggt tatttcatta ttgtttattt catcaaattt cgacaacagt ctttccttta 94621 tatcatctat aacactttta tccttgtctt cctgtgccgc tctgaccatt tccgtctgca 94681 aatattgata ctcacgaagt atggcccttg ctttgtggtc tctttcaagg cttgcttccc 94741 actttttgta gtttgtcatt tcgtccgaat tgctgatcaa ttctccaagc tctttcgcct 94801 tcgtaaaaat atccatacca atcacccttt atccggtatt atattcatta tttcattatt 94861 gcagccagca aagctctgta taatcacgta aatttaactg tttttctcac taactcttat 94921 taacctattg taccataaaa ttatcgaaaa aataacattc tagtagaaaa atttattaaa 94981 tctcataggg gtatagaaat tttgagtata ggtaatttcg ttttcattac caatgtaaac 95041 tccgactcca aggcgctcaa agtttccaag tatatttaac ctgtgtccct gggaattcat 95101 ccatccctca tgggcaaata tcgcctccgt ttgtcccatt gcaatgtttt ctccagcaga 95161 tgaatacgat attccggctt ttttcattct gtcaaaagga ctttcccctt gcaaatttgt 95221 atgggaaaag taattgttta aaaccatatc ttcactgtga gcccttgcaa cttttgctat 95281 ctcatcatcc cattcaaagg gttttaatcc ataccttgct ctgacggtat ttgcaagatc 95341 aaaaacttcc ctctcaaagc ttattctaag ctcttcggaa ggcttgccgt aataaccgtg 95401 aagggctctt tccgtctcac aatcaatcaa aaggtacgac gtaactttgt tctcatcaaa 95461 gatatcaaaa aatacagtca caaaatattg atcatttaca ttgaacacct tctgttcatt 95521 cgaatttttc atcatgtaat aagtatttcc tttttttatg tattccaaag gttttcccag 95581 ttctttttcc gcacttatac catccgttcc aacccctatg gcttcattga gccggtagta 95641 aggagagttg gtaaatactc caaccacttt gtcatcttct atccctattt gaatatattt 95701 cagaagatta ttattataaa tataccagtc aaaaccgtat ttgctcaaat caatacggtc 95761 aggttcccca aatgtctcta ttacgtcact tagggatgcc ccaattaacg tgcttacctt 95821 cccgtcaaat acaaattcct gagtttcagg atcttcgtcc tcaacatttt cgtcatatgt 95881 attgataata accgttcttg tagcatcatc ccatcctaca cttgcgccaa tactttcaga 95941 tataaatctt acaggaacaa gggtccttcc tcctacaatc ctggccggta cgtcaagcct 96001 caccgcattg tcatttatat aagctatgtt actgttgatt ttaagagtga ttacaatgtc 96061 atttttataa acatttactt ttttcgattc cggaacccat tcaacatctg cattgataga 96121 ctcaaacacc ccacgaacag gcacaagggt cctaccgttt tctataacag gcggcacatc 96181 caattgtaag tattgaccat ttacgcatat ttttatatca cttaaagaat aaatatcaaa 96241 agcaccgatt gaaaacaaaa ccgtaaatac agtaagaaaa agagccaacc tttttagcat 96301 taattttttc atcacaattc atctcctgat aaaaaataac gcaatttact tataataata 96361 tactatacga ttataatatc gtatattttg ccgcttcttt caataggaaa ttatttttca 96421 aagcacaact tcttctttca agctttcaag caaatttatc acttcatgca gtgattttaa 96481 ttctctatac accaattctt cgacttcgtc aggtcttctt atgtcaggaa taagcaccgg 96541 aaacattttg gctcttgaag ccgcttttat gccgttcgca gagtcctcca gcacaataca 96601 ctcttcaggt cttttgcctg ttcttcttgc agcctcaagg aatatgtcgg gttcgggctt 96661 tcctctctcc acttcatctc cgcagacaat ggcatcgaaa cgttctctga tgccggccaa 96721 agttaaatat ttttccgttc tttttcgctc tgtagacgtt gcgacagctt tcattatgcc 96781 cctatggtca agatagtcca aaagttcgaa aagccccggc tttacaggca taccgttttt 96841 ttcaatataa tccagcacat atttcaccct aaggtctctt atatcataaa agggcaaatc 96901 gttgccgtaa tattttttga aaactttctc tatgctcttg acattcaaac cagtcatatc 96961 ccttaaaaat tcttgcttta tttctatacc gaaagatttt gccgcctcat gccagcctaa 97021 aactccaatt ctttcggtgt caaacatcaa gccgtccata tcaaaaataa ccaatgaaat 97081 cttatacttt ttcatagcca ctttaccatt atccttttct taatttttta aattttttat 97141 aaaattatta aaaatttttt tcttatactt cttcttttaa tttttctgcc tttacaagca 97201 tttttgacat tttgtgaaaa caaagaacat gtccgttttt cgtaacaatt ttgttgtatt 97261 ctatcggaac atagcccctt ttttcgtaaa gactgtacgc aggcagagaa gaatccagca 97321 caacattggc ataacctttg tttgctgctt gttgctcaag tctgtcaagc aacatgctac 97381 cgtatccttt gccttgaaat tccggcaaaa caaacattct tttaatttga ttttcataaa 97441 tggcacctgt gccgacaatc tctccgtcac attcaatcag aagaataaat tcaatgttta 97501 cggctttctt gatattctcc aatgaatggt gtgtaagaaa aaaatccact actccttccg 97561 ggtaatattt tggatacact tctttaattg tggaatgaac aatactgtgt attacttcaa 97621 catccttaaa atcggcttta ataaatttca tagacactca ccctgttttc ccggcatcta 97681 cacatttttt ggatgttttc tttttattat aacatatact attctagttt tttaccatat 97741 gtcaaccttg gccggccgcc tcattcaatc ggaatttcag gcaatcggaa tttcagggta 97801 aataaatatt gcgcgcgtca attaatttta aacttgccca ccaattcatg catatccttt 97861 gccgattgcg ccaacaggct tgatgaattt gtaattttat ccatagtttc cgtttgagtt 97921 tccaaagatg ctgctatttc ttcaatagaa gcagaagtgc tttcggcaac ttccattgtt 97981 tgatagaagg attttgtaaa gagtttactg ctcgaaacca ccctttcggt gacaaccacc 98041 aaatcattga ccttttcaat aatatctctg gtattgttat ttatcatatt aaaggcgttc 98101 ttggcatcgg ataccaccaa aatacctttt tcagactgtg ctattgtcgc atccgctata 98161 tttatggttt tatttatata tgtctttata tccgaaatta ttttatttat ttcaacagtt 98221 gaatctttgg attttaaagc aagtttcctg atttctgatg ctataaccga aaatcctttt 98281 cccgcctcac ctgcttttgc agcttctatt gttgcattca tggccagcaa atgtgtctga 98341 cttgcgatat ctgaaataac tttgataatt ttaaagatat tgtcagattc gcggccgagt 98401 tcttttaaac atttgttcga attcagtata ctgtcgttta tgttatccat ctgatttagt 98461 gcttcagtta ccagcttgtc ccccattgaa gcactttccc cggcatttaa agatacttct 98521 ctggtttcag tcaaaaaatc agccatcttg gccatatcgc tcaaaattac ttccatctgc 98581 tttttggctt cgtcaaccgc ttccacctgt tcatttgtcc cctgggctat atcctgggct 98641 gcgctcgaaa tgccttcgaa tgtactcatc gacatcgaac atctgttgtt tatttcttca 98701 gaagatcttg acaacaacag ggatttttca ttaatgtccg ttaagatagc ttttagcgta 98761 gccaccatct cataaaaagc atttgataac attcccacct catcattgct tttataatct 98821 gaactgacgg taagatctcc tttttgaacc aattcaacat tcctgaccaa ttgcttgata 98881 ggtgttgaaa taagtaccga aacaatccat gccaggaaca atcctattac caatgacaac 98941 agaccaatgc ctatcatgtt gtacgtaatt tcatttacca attcttttaa acttttgtca 99001 gttacgccta cagacaatac tcccagagtt tttccctgat agtcttttat ttctttacaa 99061 tacaaataat aatttccatc aaatattctc tgggcggagc ttaaaaattc attacctttt 99121 tcgatgcttt ccaaatctat tgtaacatcc tcattattat catacgcatt tccattggaa 99181 tcactcattg caaccagttt atttccttca taaagaaaag cgtttgtttc aagagatgta 99241 cttatttttt ttatcaagtt gttgccagcc gttatgtcat gtaacattac aattgttcca 99301 atagtttcag aattggaatc tacaatatct tcaatgctgt aaacgtttat atgatcacct 99361 tgtacaaagc cgcttctttg cataacggta ttgtcgattt ttatattact tttttcattg 99421 gcccggtaaa tttcagtatc tcctttatag acaataatat cgtttatttc gggatacttg 99481 ttcatgtatt cttgtaagct ttgtattaac tgttctttca aattcatctg tattaacatt 99541 ctaaacgcag agttttttgc tatgtttaca tttaaatttt taatattgct gatttcattg 99601 tttaaaatga tttcagcagc gacagactgg tttttcaaat tgtttttcat attctcttcc 99661 gcattgcttc tggaaacatg aatcatatat atcataatta ttattatgac aaacagaatt 99721 gttaccgtat tcagcaaaag caatttggtc ttaagagatt taaaatcaat taatctacca 99781 atatttttaa gtattttgta cctttgcccg tctgtttttt catctttttt aaacgaatcg 99841 ttcaaatccg gcttttttgc atttgaaagc agcttaatct ccgaaagttt acatcggctc 99901 aatttatcca taatataatt cttaattttt tcaggtttca ttttacccat tcctttcagg 99961 aatttctaca acttattatt tttcactttc aaaattttaa tttttaagca aaaacaggtg 100021 aaaagtcata gctttcttta aacaaactat gacttttcag tttttaaaaa aagcaggata 100081 ttcattttta ccggtaaata aagttagatt aattaccaat ataatttccc tcgtaatccg 100141 tatatactct ataggctgat tcaattgcct gaagcggcaa ctctacgcct attctgtcag 100201 cagtcatctt attgtaatag atataaactt ttttagggtc ttctattttt atacttttaa 100261 tgtcttctcc atttaagagc cttactgcaa tttctgtttg ttgttctgcc aatgcagtta 100321 aatcaaccgt tacgccacca aatgcaccat atttaaccat ggaatcaacc aaagcaatgt 100381 ttattttttt gctattctct cttaaataag ttaatgcatc ggttaaatta ccaacagtac 100441 cgtctttgag tcttacaaaa ttacctacat aaataaccca ttttatttca gggtcatttt 100501 catatttttc tatcacacta taaagctctt cctccgtttc cggcacttca taggctttga 100561 gctcaacccc tgcagctttc agctgacttt ctaccatttc ttttggatat ttggcgggtg 100621 catatttacc aattatgaat actgtctttt tgggtatgga tggatccaca acagatacaa 100681 gattggcagc tttagccagt atatcaaccg gtgtaaaatt gactcccgta acattttttg 100741 cggccacccc tgaagaatca attactcccg cttctctgca tgatggaata actacgggga 100801 atggtgcacc ctccaaagac tttgcaaggg gaatagcgat agaagaattt ataaccaatg 100861 ctaaatctgg gctgaattgc ataatttctt tagttacttc tccaactttc gtggcgtcgt 100921 cttctttaat tatcttaaat tccgtattct cagtatcata acccgcttct ttcaatactc 100981 tgaatgctgc attctcggca agcttttgcc attcttgaga atctggattg gcaaaagtta 101041 caaaagcaat tttcttgccc gtattatcaa gcctgtttgt ttgcccgcta ttttcttgtc 101101 cttgttctgt ttgaataact tccttttcag aatccagatt tgatgtgttc ttctgacttt 101161 cctgatttgg agtaattgtt tccgctttgg gtttgctggc gcatgcagca gtaaaaatta 101221 atgaaagtgt gacagcaaat aaaagcgcac acttccattt gttactaaat gccattttca 101281 tttttttatt cattcctttc acaaattaaa attttttatt gattagacca attactacat 101341 ataatgccaa ccacaaaaaa gttttataag ccttttgctt ggttgacgca tttgatttta 101401 tgtaaaccta gattctgaaa attttatcgg aagggatata aatttactga ataattcttt 101461 tgatattaga ctttgataaa atattgacag aattaatagc catacccatg gaattttcct 101521 gtttgtaacg caatttcaat aaaaaaagcc gtataggctt ttaataaaca tttcttaaaa 101581 attatccttt tattttaaac taagaagcaa gataagcaca atgaaagtac tgttattctc 101641 ttgccttttt acttgtaaat cattctattt tcaccttact atgctgccct ccagcgacca 101701 agtttttaca gtatttattc ttacattcac caacttacct atcaaacttg catcagcctc 101761 aaaattaaca actttgtttc cccttgtcct tcctgtaaaa atcttatcat ttgtcttgct 101821 gacaccctca acaagaactt caaccacttt gcccaaaaaa gtgtcattta tttccttgct 101881 tatcctgttc tgcgtttcaa gaagtctctg gaatctttcc ttcttcactt cttccggaac 101941 ctgatcctcc attttggccg caggcgtacc ggttctcttt gaatacagga aagtatatgc 102001 gttgtcaaat ctgacttttt caagaatatc cagtgtgtct gagaaatctt cctccgtctc 102061 accgggaaat cccacgataa tatcagtggt aagtgcaata tccggtatat tttccttaat 102121 ctttgctaca agattaatat aatcctcctt ggtatacttt ctgttcatca atttcagtat 102181 tctggtgctt cccgcctgaa acggaagatg caaatgttca catacctttt cacagtctct 102241 catggcataa atcaaatcat cggacaaatc tttcggatgg gatgtggtaa acctgattct 102301 ttcaatcccg ggtatcttgt taacctcacg tatcaactcg gcaaaacttg taccgtctcc 102361 aatgtctttt ccgtaagagt ttacattctg ccccagaagt gttatctcct taaacccttg 102421 acgtcctaac atccttactt cttcaagaat gtcatccatt gatctgcttc tttccctgcc 102481 tcgtacgtaa ggaacaatac aataggtgca aaaattattg cagccgtaca ttaccgtaac 102541 ccaggccttc accccgtctt ttctctcaat tgccacattt tcagctattt ggccgtcgca 102601 atcccagaca tcaacaacag ttgtctgaga atccatcgca ctgtacaaaa gctcaggaaa 102661 cttatacagg ttgtgcgttc caaatatcag gtcaacatga ctgtatgtct tctttatatg 102721 ctccacaact tccggctgct gcatcataca accgcataca gcgatcacaa gatccggttt 102781 ttgattttta aggggcttta acattccaag atgcccgtat accttaagct cggcattttc 102841 ccttacgcag catgtattgt aaataaccaa atcgctttcg tttacgttat ccgtttcagc 102901 atatcccatt tcagccaaca ttcccgcaag tttctccgaa tcatgttcat tcatctggca 102961 accgaaagta ttaagacaat aaagcttctt ctttccggtc tttacttcct tccgatagtt 103021 taattcttta atctcgtcaa taaaccgctg ctgtcttgcc atttcctccg gagaaacata 103081 aatatttttc ctgtcccttg tacccttact caactttgct aacctccatc aattgaacct 103141 ttttaaattt ttgtaatttt taagctttac atgctcagct aagctcaata ttcaaaccgt 103201 aaaagtcttt ctcaatgcaa agctttgccc tttctctggt tttatcatct gccataagcg 103261 cttgctttat aaattccgga ttcttcctta gaaactttgc catcgattct tttggatcaa 103321 gaatatattg ttcaatcatt tcaaactgtt ccctgtctat aagccccata tccaaaaccc 103381 ttttaaaaag gccaatatct atgtcaacca ttgaaaaaga tttaatatca taggatttga 103441 gcagttcagc gcctccctgt tttctgtcca ccacaacgac actccatttt atcctgccgc 103501 cgttgttttt tattgcaggt atccatgccc tctcatagct tgaagcttct gtaatcaggt 103561 ctgcaatatg aagaacgctt tcgccgttta actcttttag ttcttctgtc tttccgtcac 103621 ttgaaaccac cgtggtcaaa tctttatata tggttatatg aggcttatta agaagcttcg 103681 caataatcgg cgaaaagaac cagtcccttc tttcgcctcc tgaaatataa tcaacttcgt 103741 ttacatctat gttgtttttt ataaaatcgc acatttcatc aatcaatccc cgatatatgg 103801 ggtcagactg ataatttttc attgtttctt ccaaaattct atccgggcac tttaaaatat 103861 tctctttttc cttgtctata aactccagga gcttattggc tttttcctcg ctgccgtaaa 103921 gaaaatgagt atttatgtaa tacgggccta tagttcccga tgtataccaa aaaggcttgt 103981 ccttgggaca tactcttatg gcatttgtat caaaaagcca ctttatcaac ttttcgttat 104041 tcttaaccaa ttttatactc ctcctctgaa aaactgtaat tattttatta ataatactat 104101 aaattattgt atttatatgg tataatataa gtgtattaag ctatataatt atactataaa 104161 ttatgccact caaaatatga aaaataatat tttgttcaaa atgttgacga agacgcgatt 104221 tatattttca attctgtttt tggggcgcaa acaatcgcgt tgtcaatatt ccgttgagtt 104281 ggcatgatat atggtatata tacttatata atatattaga ttaactccaa ttggaagaat 104341 aatttttaaa atcaatcccc tttaagaatt gacataaaac gcattaacta ttatggagcg 104401 atattataga taatttttat ataaaaaaga taaactaccg actcttgtta ttttatgtat 104461 tctatcttca cttatttctg gaacaatgtg ggaggaatgt atgatgagca gtagcagatt 104521 aatttcgtgt aacagggact ggaccggaat tacagtactc gacaaaaaag gtaaaccgat 104581 tttccttgac taccaccaga taagtgaaat caggtttggt taccacacta taacaaaact 104641 gttttcaaaa aaaaccagtg aaaaaatcga aatacgctta aaggattcaa ccaaaccgat 104701 actggttcta aaaccaatgg attgggaccg tttcgatcaa tacaaacaag aaataaccag 104761 gtttgcaaag gaaaacagaa taaggctggt agagtacgaa taatttctaa ttttaactcc 104821 agggctttat gcactggagc ttttacttta ttttattatt tttttatttt atatcaggtt 104881 gtacccgtca aaaattaaac atcctccacg catatatatt acgcgtacac ttaaattaaa 104941 taatttaaat aattgatttt cccattccga caaacttaat ctcaaaagta caaaaaagcc 105001 agccttcgct gtcattcacc aaggctggct attaccctct ttatcaaatc ttcatcatcg 105061 atagtgcact gtattacttc tccgattctc ttccttggaa gtacaaaggt aagcttgctc 105121 cctttaattt tcttgtcata aaacatttga ttgtaaacct tgtccacatc aatgccttca 105181 agccttgtcg gaagcccgat tttatccaaa gtgttcttta cacggttaac gctttgctca 105241 tcaatcatct caagatgcag ggccatcctc atggcgccta ccattcccaa tgaaacacat 105301 tctccgtgca aaagctcaaa attcattacc gtctcgattg catggcctat cgtgtggcca 105361 aagttcagga ttgccctaag gcccccttct ttttcgtcct tttcaactac cgaagctttt 105421 atggagcaat tccttttggc aatatattgg agcacagctt catcatggtt taatattttg 105481 tgaacattat agtctatata ttcataaaac tcttcatcca taattacgcc atgcttgacc 105541 acttctgcaa gtcctgcctt aagttccctt tcgggcaggg tttttaatgt attgacattt 105601 atatatacaa atttcggctg gtaaaaagcg ccaataatat ttttggttcc ttcaaagtca 105661 actcctactt ttccgcccac actgctgtcc gactgggcaa gaagagtcgt gggtatctgg 105721 acaaaattta ttccccgaag aaaagtggca gcggcaaaac cggttatatc tccgacaact 105781 ccaccgccca acgccatcag cgtagcactt ctgtccagtt tcagaccaag caggtatttg 105841 taaatatccc tggtggtatc caaattcttg ttttcctctc ctgcgggaat aacaaactta 105901 cttacttcat atcccgcatc cgaaaaagct tttacacatt cttccgcctg gtatttgtct 105961 acattggtat cggttattaa aaccatcttg cctgtaagtt ttgcactttg aatgcattta 106021 cctatttggg aataatccgt acttatataa attgggtaac ttctgtcctg taaattgacg 106081 tttagtttta tcatcttgca atcagcctgc ccttcggtat ttgtatcagg ctaaaaggat 106141 aaacctttta gcctgtaaaa tcaaccgcaa acttagccaa ctacttctgc acatctgtcg 106201 caaagagtgg gatgtttttc attctttcca actgattcgc taatcatcca gcatctttcg 106261 catttagatc ccgaagccat ggaaatatta actcttattc ccttaacatc cggatcttca 106321 tagtacttac cgtccgaagc ttcatcataa cccttaagct caaagtctga aactatgaaa 106381 actgtaacaa ggtctttctt aataggctct ataaagtcat agttttcctt gtccgcaaag 106441 attgtaacct ttgcattcaa agaatgccct attatttttt ccgttcttgc aatttcaaga 106501 gccttagata ccacgtcacg gatttcaatt atcctgtccc acttttcctt aagcgccgca 106561 ttttcatact tctcattcgg ttcaggccaa tagttgagct gcacactttc agggtcgttg 106621 gtgcttctgt gaggcataaa ctgccacact tcctcgctgg taaacgccag taccggagcc 106681 agcattttca caagagcctc caatatttca tacattgcag tctgcgccga tcttctttct 106741 ttcgagtcag ccctgctggt gtaaagtctg tcttttataa tatcaagata gaagttgctc 106801 atatcaacaa cacagaaatt gtgtattgca tggaacatca aatggaactc atatttttca 106861 taggcatcgt taactttctt aataagcccg ttgagcttca tgagtgccca tttatcaagc 106921 tcgttcatct catcatagct taccatatct ttattcgggt caaaatcata tatattgccc 106981 aaaatatatc tgcaagtatt tctaatcttt ctgtatactt cagaaagctg ctttaatata 107041 tccttggata tcctgatgtc cgtcctgtag tccgaagatg caacccataa tcttaatata 107101 tccgctccgt attcttttat cacatcttca gggtctattc cgttgcccag ggatttggac 107161 atttttcttc cttcaccgtc aaccacatag ccgtgggtca gcactgtctt gtaaggagcc 107221 tggccttttg tggcaaccgc cgtaaggagc gatgactgga accatcccct gtgctggtcg 107281 cttccttcca gatacatgtc cgcaggccat gtcaagcctt ccgttgtttc aagaacggca 107341 gcatggctgg aaccggaatc gaaccatacg tccatgatgt ccttttcctt ggtaaattct 107401 ttgcatccgc attcacattt cgtaccttcg ggcaggatat cctttgcatc atactcatac 107461 catgcatcgg agcccttttc cgcaaacagc ttggccacag ctttaatcgt gtcatcattt 107521 ataagttctt tcttgcaatc cttgcagtag aatatcggaa taggcactcc ccatatcctt 107581 tgccttgaga tacaccagtc accgcgttct cttaccatgt ttgtaattct ttcctgaccc 107641 cattcaggaa tccactttac agttgaaatg gcatcaattg cttcctttct gaagccttct 107701 atcgacgcaa accactgctc tgtagccctg aatattatcg gatccttgca tctccaacag 107761 tgaggatact ggtgaacaat cttttccgat gccaaaagat tgttggtgga tttcagctgc 107821 tcaataattg cagcatttga cttctcataa tacaaacctg caaactgtcc tgcttcggac 107881 gtaagataac ctttgtcatc caccggcact atcacaggta tgtcatactt tttacatact 107941 tcaaagtctt ccgcaccatg tcccggagcg gtatgaacac atcccgtacc tgcttctgca 108001 gtaacatggt ctcccaatat aatgacagaa tccctgtcaa ggaacggatg cctgcaaagc 108061 atgccttcca gttccgctcc cgtaaatttc gccttaacct cgtattcttc tatccctgca 108121 accttcataa cattttcaag aagctccagc gcaattatat agtactcgcc gtttgccttc 108181 accaatccat actcaaattc tccgtttaag cagattgcaa ggttgcccgg aagtgtccag 108241 gtggtggtgg tccatattac aaaatatgta ttttttaaac tatccaccag accgccaaac 108301 ttgcccttgt cgtcttttac ctcaaactta acgtatatag aaagtgtggt gtcttccgca 108361 tactcaattt cagcttccgc aagggcagtc tcacattcgg gacaccagta cacaggcctt 108421 aatcccttgt atatataacc ttttttggcc atttcaccga atacttctat ctgctttgct 108481 tcaaactcct tgttcaatgt aatgtaagga ttatcccagt ccgctcttac accaagtctt 108541 ttaaaggctt ccctttgtac atccaggtac tttaaggcaa atttcttgca tgcctgcctg 108601 aattccacag gacttacctc atgtctttta agcccaaact cttttatagc ccgctgctca 108661 atcggaagtc catgggtatc ccatccagga acataaggtg tttcatagcc cttcatactg 108721 taatacttta taataatatc ctttaatatt ttatttaaag cagttcccag atgaattccg 108781 ccgtttgcgt aaggaggacc gtcatggagt acaaacttag gctttccggc atttttctta 108841 agttgcttgt ggtaaatatc catctcttcc cactttttca aaaactccgg ctctctttga 108901 ggaagattgg ccctcatagg aaaatcagta ttgggtagat ttaaagtttt tccgtaatcc 108961 tctgccattt tcaaacctcc attaatgtaa tatttatttg aataacacaa atttcacata 109021 aaagtagcca aaacaaaaaa ctctcatccc aaaaagggac gagagtattc tcacgcggta 109081 ccacccaaat ttattatgaa tatatattca tatatatatt cataatcact caatttgatt 109141 aacggctcat caccggccaa gcttactcgg aaagctttga cccctttcag ccggcaactc 109201 gtagatgatt ttcaaaggct ggctttacag gattcgcacc gaccacctgc tctcttcaaa 109261 agcttcacct tctactcgtt ctactcatcg cttttgtcac tattcaatta aagaaaatta 109321 tacaatatat aatatttgaa tgtcaagaaa ccagcttcaa cattttaatt attccgcttc 109381 ttcctcctca actatgggtt ttaatatctc caattgggaa agaagaaggg attccacctt 109441 gctcttgtaa gaatgaagct ttcttttcaa ttcctcatat tcaaacttta ttttaaggac 109501 ttcctgattt gcctcatcta tcattttttg agctttgatt tcagcttctt tgataatatt 109561 ctccgccttt tggtagctgt ttctttttat ctcctcgctc gtctgctgtg ccatcagcaa 109621 agtgttctgc aaggattctt ctatattctt gtaatgagca atagcttcat ttaacattgc 109681 cactttgtct ttcagctcga tattctcacg tatgtatgcg acataatctt caattatctt 109741 atccaatact tcatttacca tgtcctcact gtatccgccg acaacacttc ttttaaacgt 109801 cagattctcc aaatcattag gcgtatagtt catagcaaac acctcgttat atgaatttct 109861 ttagtaaaat gtggattctg tcttttttgg ttgtattgcc tactttctca acaactaccc 109921 tgccttttcc ccggattgaa attgtatcac cctccttgac aagccttgca ggattggtgg 109981 ccgtctccca attgacggcc actttttccc ctcttatcaa atcggccgtc ttgcttctgg 110041 atatgccaaa tccggcactt gctacagaat caagtcttag ggacgcaacc gtggagctta 110101 tttcttttac cttcggctct aaaatgtcaa gctcatcagg gtttacaata tcaatttcaa 110161 cgcgggcgtt gcccactttc gtcaaattta tccttatata atctgcaata tcttttaata 110221 caaccacaaa agcaaaatct tctcttacaa gaatatctcc aattttttct cttttaatac 110281 ctaatcccat taatgagcct aaataatctc tatgggaaaa attctccctt gtgtttggct 110341 ttattttaag tatttcaaaa aacccggaaa attcactttc tatgttctca ggcatataat 110401 aagggcagaa aaccacgacc gttctctctg ccccactaaa tcccccataa aagacatgat 110461 cccttatacc gctcatttca agacattttc taaccacatt ttgctgataa gggtccaaaa 110521 aatccgaatg ggtgtaactc ataattttct gggataaggt atacttgtct aaaattcttg 110581 ctaccaaaag tttgtcctct gccttcgaaa tccctctcaa tatcacttct ttattcatac 110641 agctcaatac accttgactt ctgtctatat cataatatct ataaacccgg atacaaccca 110701 aagtattaac agcgcaatga ccggagaaaa atctaccgtt gagttttttc caaaagaagt 110761 attctcaagt agactacgaa taggcgacaa tatcggctca gtaagttgta atataaactt 110821 tacaaatatg ttattttttg gtatcgaaaa ccacgacaat agaaccctta tcacaatggc 110881 ccactgaata atttccaata aaagccccaa ggctctaagt gccgtgatag tcagattgtc 110941 accttccatt tacatctcta tcctccaact atttcagcca cgggaaaaca gcttttcctg 111001 ttatatcacc tttaaaatct cccataatat ccacattatg cggagcaacg atgaatatat 111061 catttgaaac tttttgaata cttccgtcaa gagcatatac ggagccgctc aaaaagtcaa 111121 ctattctctg ggctacttcc ttttgcacac ttccaagatt cacaactacc ggcttcttgc 111181 tctttaaatg gtcacaaaca tcttttgcgt cattaaagct ctccggctgc ataacaatta 111241 ctttaaattg cgatgccgaa tgaatgttaa caaccttgtt ctgagtcctt ctgctgctta 111301 aaggttggat aaattgaggc ttttttgact cctcctcttc aacatcctca gactcttcca 111361 cggtttcaac atcctcttct tcatcctctg tttcccagcc cacaaaattc aaaaccttgt 111421 tcaatattgt tgacatattt tctccctcct gtatttatct tttgtaaaat atattattaa 111481 ttgtgaatat cagcctcaat aaaactttca caattaaaat tttagcttct gcttccaaaa 111541 agagcagtac caatccgaac catgttggct ccttcttcta ttgcaatttc aaaatcgttg 111601 ctcattccca tggacaaaat ctccatatta ctattatcaa acttttcttt gccaatgtca 111661 atagataagt cccttaattt actaaaaaca taccgtacgc tctcgggatt ttcagcatat 111721 ggagccatcg tcataaggcc cttcaccctt atattgggca tgaaacttat ttccctgaca 111781 agcccataag catcgtccac agaaacaccg aatttgcttt tctcaccgga aacattcacc 111841 tgaaccagaa catctacagt tttccccaca gactcggctc ttttttgtat ttccctagcc 111901 aattcaatcc tgtcaacaga gtgtatcagg gaaactttat caacaatata ttttaccttg 111961 ttggtctgaa ggtgtccgat taggtgccat ttacatttcc tgctgtttaa tatatcgtac 112021 ttttttgtta attcctgaac cctattttca cccaaatcca caacaccttc atcaagaatt 112081 ttcataatac gttccggttc aacggttttt gtcaccgcaa caagcgtaat gtcctttgca 112141 cttctgccgc tcttttgtgc ggccttttca attctctcca tgacagaata tagatttctt 112201 ttgatataat ccaactcccc gttcattttg acccgactcc ccatttgcaa attattcgtc 112261 agttaattta tgacttgtcc ttcctctatg ttttttggat ttataatata gcttgaatac 112321 aagctgactc ctccatcttt gtaatcttca acattatcta tcacagcaaa attgtcattt 112381 tttccgacaa ttttgacagg aacaaaagtt gcccttcttg ccttaaccaa tgcaatttcc 112441 gccctcatcg tattcatatc aatattgaca aggcttttaa ctggaacaat cagcccttca 112501 taacggctct tgataagatc gacatttatt accctcaaac ctgcggtatc actcaaagcc 112561 ttgtccgtcc gcaccgcaat cacaaatttt ccgtccattt cattggattt gtacgcaatc 112621 gtcccgtcaa caactctgcc aatatcatta atacggactc ttaaataatt atccacttta 112681 aaatcatcgg ctttttccct gtccaggaca aaaactatat aatagtctat gccgccaatc 112741 accttgacaa aaggtttgtt gtactgcgta ctcaagtcat ccgttttttt tctgttttcc 112801 acgactttta tcataccaag catttccgga gtaatttccg gtattttttc aggattgaga 112861 atttcttcat atccgtcaat cacataagat actattcctg ataaatttga aacaatattt 112921 cgtttgtttg cgtttatact gtcctgaagt atcctttttt cattttcaag agcttttatg 112981 ttggcgtccg tatagctcaa gtctcctgaa atggtagcct tctttttaat aagttcatca 113041 atttcgtttt ttatttgctt aacctccgaa atgctgtttt tattgctctt ctttatcaca 113101 agcaccagct tttcctgtat ttcctggtca agctttttta tatcctcgga aaaaaaattg 113161 tcgtttttgg ttttctccct ctttgcctca attattctta ggtcaagagt cttcaaatct 113221 tccagaagtt tctccgaaga tttgtttaat actgtggcaa tagtatctcc cactcccact 113281 ttttctcctt cttccacatt ccttatgctg attccgtcgg aaggagagtt gattactgtc 113341 tcgtctctta caatgtaggc atcagtggtc acatagtctt ccaattcccc cattcttatt 113401 atatccgtgt ggatattttt gccgtaaatc caaaatataa aagatggaat atacagtagc 113461 aaaaacaggg caatcaaaag acctcccagc tttacctttc cattgatttt tcttttgttc 113521 tcttccggca tttttatcca ccttccggcg ttagattttt attattccct tctccagcat 113581 tttttgtatg gctaccataa ttccaagctt tacatgttca aaaaccaatc ctccctgcat 113641 ataagcagta tatggagatt taatcggcgc atcggcacta agttcaatgg acgaaccttg 113701 aataaaagct ccggcggcca ttattacagg acaatcatag ccgggcatgt cccagggctc 113761 cggtgtgaca aaagaatcca caggcgaacc cttctggatt ccctggcaaa aagcaataag 113821 actttcgggg ttattaaacc tgacggcctg aataatgtca ccccttctgt cgtttacttt 113881 aggacttgtc tcaaaaccca acgcctccat aaccccagcg caaaataccg ctcccttaag 113941 gctttcggca accacgtgcg gcgccatgaa caatccctga aacatcagcc tgttatgtcc 114001 caaagatgct cccacatgtt tgccaagtcc cggagttgta agcctgtatg ccgctttttc 114061 aacacattct ttccttccgg caacatatcc tcccgtagga gcaagaccac cgccgggatt 114121 ttttataaga gaaccagcca caagatccgc tccaacctct acgggctccc tctcttcaac 114181 aaactcaccg tagcaattgt ccacaagaac cactatatct ttttttatac tttttacaat 114241 atttatagcc ttttcaatct catctatgga caaagccggt ctccattcat atcctcttga 114301 cctttgaatc agaaccattg cggttctttc atttatcgca ctttcaattg actcgtaatc 114361 aatactgcca tccttcaaca aatccagttg gcggtatgtt acgccaaatt cctttaaaga 114421 gcctccccct tctcctctta agccaataac ctcttccaat gtgtcataag gctttcccgt 114481 aatcgccaaa agctcatctt tcggcctgag atgtccataa aggcatacgg ccaaagcatg 114541 ggttccggat acaatttgat gtctgaccaa agcatcctct gctttgaaaa tatccctgta 114601 aacatcatcc aaaacgtctc tgcccttgtc atcatagccg tatcctgtag tgcctacgaa 114661 atgggagtcg ctcaatttat tgttctgcat tgccttgatt actttatact ggttgtactc 114721 ccggacagaa tcaatcctgt caaatacggg agttatcttg ctcatcaccg attcacaaat 114781 ttcaagtacc ttgtcatcaa ttccaaattc attctttaaa taattttttg actcaaaatt 114841 cattgctttc cctcaaatcc tatatatttt tatcgtcaaa agtttgtctc cttcaaccat 114901 acatattatt ctagcacatt cgcttttaat ttcaataata tccaatcaca aaaataaaaa 114961 tggatactga acctttcccg cattgtttat aattcgccgc aggctttgta aatcctccac 115021 tcaaacggat ttaggcatat gtttatcctt tttttgtcaa cattgagtct tttttcgtct 115081 ttcaaagact caaaagcttt taccgtgtca aaagaatctc ctgtttctac tacgacattt 115141 tcctttcggt ccaatgtatt catggcaaca ataattccgt tttctccccg gccccttctg 115201 tatgccagta tcccattgca tcctgttaca ggaagttctc catattctcc agttctcaag 115261 gcatcgaacc tcttcctcaa gccaatcagg aatttataca actcgagagt ttttttgttc 115321 catttcgctt cgtcccatat catcggtctt ctgcaatcag ggtctccttc gccttccatc 115381 cctatttcat cgccgtagta tatgagggga actccaggaa aggtaaactg gaacactact 115441 gccagctcaa atctcttttc atctccgttg caaagagtca aaaaccttgg cgtgtcatga 115501 gtgcttatta tatttaccag gctgcttagc acctttttgt taaacttcat aatatagccg 115561 cttattctgt tcctgaaagt ctccacatca atggacctat aggcaaaaag gtcatttatc 115621 atggctttca acggataatt tatcaccgag tcaaactggt ctccccaaag ccacgaagac 115681 gcctcgtcaa atatttcgcc aatcagcacc acatccttgt tcaaatcttt cagcatatcc 115741 ctaagctttc tccaaaactt tcggtccacc tcatccgccg catcaagtct ccatccgtcc 115801 accccaaact ccactgtcca atactttacc acatcaagaa agtattttgc cgtctcagga 115861 tttccggtgt taagcttcgg cattcctcca taaaaggaaa agcattcata attgggtctt 115921 ggatatccct gaacgggaaa agaatttata aaataccagt ttgcatactt tgatttttct 115981 cctttttcca caacatctct gaatgcaaaa aacttgtctc cggagtgatt aaaaactccg 116041 tcaaatatta cttttatacc gtttttgtga cacaagtcca tcaattccct gagctcttct 116101 ttacttccaa acatcgggtc aatttcataa taatcgacaa catcatagcg atgataagat 116161 tccgatttga atatgggatt taaataaacc acatcaactc caagtttgac taaatgatca 116221 aaccggtcga ttatcccttt aatattgccc ccatgtatcg ttcttttgcc cgaattttcg 116281 gtatccggcg gaaactttgc aaatctgtcg ggaaatatct gatatattgt tgaattgcga 116341 aaccattcaa cctcatgaaa tatgtcgtct ttgcatatat aagaataggt aaaatgtccc 116401 cactgaggca tataatcaaa aaatccgtcg ctgctgtacc attttattga ataattatcc 116461 tcaagataaa acatatactt aattctcttt ataccgacat taagctccac ctcgtaatag 116521 tcaaacattc catcgcttgc aactttatcc attttcactt ttcctctttg tgacgtatca 116581 tacttttcat gatagatgag aatgcaggtg tttacatcgt ttttagccgt cctgagccgt 116641 attaccagag tgtcgggagc aacaggaaat gcaaactcgc tgtaaggttt gtgatatatt 116701 gcctcaagtt tcattacgga taccccattt ccaagtttga tgcaacttta agcggatttc 116761 ctttttattg tacaacactt tcaaaataag atgtgccata taatatgtcg tataatgtat 116821 aatatgttgt atagtattat aataccatat ttcacagcca aatttaacct tgttttcccc 116881 gtcacctttt ctttcacttg gagtgccggc ataaaaatga cccctgccat caggcagagg 116941 ccgtcttttt aaaatccttt taccatccaa gcttgttttt tatttccgca gtaagccgct 117001 cagccatcag ctggtgggtg gcaatacttg gatgccagtc ttctccgtat ccggtgcttc 117061 cgtcctgctg ccgaaactca acaaaataca cctttaaatc cccgcttctg ttacaatcat 117121 ttacaacttc cgtaacataa ctgcggcaca aatccaggcc cgttccccaa agcatcggac 117181 cgacacagca gaatatatgg gcatccggat agttcctgcg aacttcactt ataaggtttt 117241 tatatgccgt tacaaacttt gttttatctg caaatgatgt agaaaaatca ttggtaccaa 117301 gattgattac aacaacctga ggcacatatt tgctaaaatc ccatctgact ccgctgtaag 117361 gaagggtata aggataacgg tccattataa gaggtccggg ggctccgccg tagttcatgg 117421 taagtccgat tccggaccac gcaatcatat ttgcacttgc attcaaatta cgggctgtaa 117481 ttgccgcata agacatatag ctgttttcat ttttcggtgt aaaagactgc tccttgcttg 117541 ttccttcatt tccgtatgca catgtgatgg agtctccgat aaactcaatc tttctttcca 117601 aaggcttcgg tgcggcaaga agctttcctg aaccaaaatc aaacccaagg aactgaactt 117661 ctcccaagga tgcctctgtc ctcttccaca atacaagatg atgagctcct tctgcaagac 117721 cgcttacaag ctttacggta gaggtagtag cgttaaccga aaaaggagga agaggattgc 117781 cgtctacaat agcctggaac cagttctcac cgccggattt gatagtcaca cttgcttccg 117841 tgccgtaaaa attcagctca acattgctgc cggaccaggc gcatttcgga ccgttcggat 117901 ctgaaaaatc gaatcttccg ttatacaaaa tgcccggatt gtcttcatca ggtgtttgag 117961 aatcctccgc aggaaatttg tctattgagc gcagtagata ttttttcatc aataccaagt 118021 cggtggaatt gattttcaga tccgcattta cgtcagcggc tataattccg ctaggacttg 118081 ggaattcttc tatgccacgc aaaatatatc tctttagcat tgtacagtct gtagaattta 118141 tttttccgtc cccgtttacg tcaccgtaca aaatatttgc tgtcaccgtg ggcgaggggg 118201 tcggcattaa tgtaggtgta ggagtcggtg aaactaaagg ttcaacgccg gcacctctca 118261 taagagcctg gacaatttca ggataatacc atgagagagt ttttctgttc agcaatgcat 118321 aagtctctgc atcacccgga ttgtaatagc cgttatccca ccagaaaaca gcaattcctc 118381 ttgaaactgc ttctcttgca tagtgctcgg catgagccac ccttgaagac aggttgttct 118441 tgtcaatggt tccgaattct ccgataatta cagcccttcc gtttttcaca aatctgttgt 118501 aaatagcatc aagttcactt gtaagagaag ccttgtcata gtcacttccc caatatgaag 118561 ttccgttgac atccatagca aagaaatacg gtgaataagc atgtatggat actatgactc 118621 tgctgtcatt gttcggaatg acaaggtcgt ttaatgcaac atccaggccg gttgccgcat 118681 tggtcggaac cagtatgaat cttttatcgt tatttccgcc gcttgctctg atggtattaa 118741 caaccgccaa attaaatctg tttatcacat ctcggttttc atacgttccg cccatccatt 118801 ccataggtga acctacttct ctcggttcgt tcattgtctc aaacaacaaa tggtcgtcat 118861 aatctttaaa acgggttgct atttgttccc aaacttttac aagtttttct ttactccttt 118921 gctcattggc atatgtaggt ataatccatg tattgtcatg gtgaacattt atgatcgcgt 118981 acataccgca gtcaagaaca tagtttacca cttcctcaac tctgttcagc catgcttcgt 119041 caattttata gtccggagca ggtccgatgt gcgtatccca ggtaacaggc actctgacgg 119101 cattaaagcc catttccctt accttttcta tcattgcctt ggttgtcctt ggatttcccc 119161 aggcagtctc tgtaggagca tccaaagtat ttcccaaatt ccatccgatt tttatttctt 119221 taaccaaatc tattgctgaa atatcacgca tgcccctcat tacaagctcg tttccgcttg 119281 catccaaaag ctttgttccc gatacctgaa agccttttac cggtgatgcc gctacgactg 119341 aaaacgagcc taagatgctt accagcatca caagcacaca aaccaaagaa acaatttttt 119401 tcacattacc ctctccttta caaaaatcct ttacaaaaaa caataatctt ttactttaaa 119461 tcctcttttc ttgcatcaat caactttatt cttacagctc ccccttccta tttggcttga 119521 aataaaacat tataacaaac taaacggtaa tgttactgtt tattatatta attcgaaaaa 119581 tcattttctt ttggacagcg caaagcaaaa aataattaaa aacatagtaa cctctgctga 119641 aaaaaggttg cactttgttg gaaacccggg atatataaaa gaagctccaa agaatttgga 119701 gcttctttta tatatccgtt tattaaaaac tttaaaaatc cacaatatat tttctaattt 119761 ctaagaagta ttctctttag tattgaaatg tctgtagagt tgatattgcc atcattgttc 119821 atatcagcat ttgtcacatt tattgaattt atatccacaa ctttcagtat atatcttttc 119881 aaaaggctga aatctgtcga attgacctga ccgtccaaat taacatcacc ttttttaacc 119941 agaggagaat ctgtgggagt cggagacgga cttggagttg gctgcgtttg tcctgccaaa 120001 gcttttagta tgtcaatcgt atacttgtac caaatatttg caatctttgt gtatcctatt 120061 tcgctcaagt gcaaaccatc ccatgaaata tcggtgttcc tgtcaaactg aatctcacta 120121 agctttacaa aataaacttt cttgccggca ttggccttct gttgaactat tcccggaatc 120181 accgcattgt attgcttgac cgcttcaggc cacggataat aatcggccac aaacagtgtt 120241 acattgggtt tcactgtgaa aatctggtct ataagattac taaggcctgt tgcattcacg 120301 tttccgctca aaagcaggtc atttcctcca atccacagaa ataccacatc cggg //