LOCUS NZ_ACVX01000012 80959 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00036, whole genome shotgun sequence. ACCESSION NZ_ACVX01000012 NZ_ACVX00000000 VERSION NZ_ACVX01000012.1 GI:256004338 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 80959) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 80959) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000012. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..80959 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene complement(67..477) /locus_tag="ClothDRAFT_1181" CDS complement(67..477) /locus_tag="ClothDRAFT_1181" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: similar to tumor suppressor TSBF1" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429320.1" /db_xref="GI:256004339" /translation="MSYIKERVSYLKGLAEGMKIDDSTNEGKLLKAMIEVLDDIALAV EDIEEVQEQLEEQVDSIDEDLEEFARILFDEEEDDDVLAQIECPHCNKVFDLTEDMID GDSDSFECPYCHEEIAFEWDCDCEDCSEEEENKE" gene complement(609..1166) /locus_tag="ClothDRAFT_1182" CDS complement(609..1166) /locus_tag="ClothDRAFT_1182" /inference="protein motif:TFAM:TIGR00038" /note="TIGRFAM: translation elongation factor P; PFAM: Elongation factor P ; Elongation factor P/YeiP protein; Elongation factor KOW domain protein; KEGG: afw:Anae109_0693 translation elongation factor P" /codon_start=1 /transl_table=11 /product="translation elongation factor P" /protein_id="ZP_05429321.1" /db_xref="GI:256004340" /db_xref="InterPro:IPR001059" /db_xref="InterPro:IPR011768" /db_xref="InterPro:IPR013185" /db_xref="InterPro:IPR013852" /db_xref="InterPro:IPR015365" /translation="MISAGDFKNGVTFELDGQIFQVIEFQHVKPGKGAAFVRTKLKNI VTGATIEKTFNPTDKMPKAHIERKDMQYLYNDGDLYYFMDTETFEQLPLGKDKIGDAL KFVKENEIVKVLSHKGNVFGIEPPNFVELEVTDTEPGFKGDTATGATKPAIVETGASI KVPLFVNKGDIIRIDTRTGEYMERV" misc_feature complement(612..1166) /locus_tag="ClothDRAFT_1182" /note="elongation factor P; Validated; Region: PRK00529" /db_xref="CDD:179058" misc_feature complement(987..1160) /locus_tag="ClothDRAFT_1182" /note="Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207" /db_xref="CDD:149330" misc_feature complement(789..971) /locus_tag="ClothDRAFT_1182" /note="S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-...; Region: S1_EF-P_repeat_1; cd04470" /db_xref="CDD:88435" misc_feature complement(order(807..812,825..827,900..902)) /locus_tag="ClothDRAFT_1182" /note="RNA binding site; other site" /db_xref="CDD:88435" misc_feature complement(615..782) /locus_tag="ClothDRAFT_1182" /note="S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-...; Region: S1_EF-P_repeat_2; cd05794" /db_xref="CDD:88469" misc_feature complement(order(624..629,642..644,693..695)) /locus_tag="ClothDRAFT_1182" /note="RNA binding site; other site" /db_xref="CDD:88469" gene complement(1382..2461) /locus_tag="ClothDRAFT_1183" CDS complement(1382..2461) /locus_tag="ClothDRAFT_1183" /inference="protein motif:PFAM:PF00557" /note="PFAM: peptidase M24; creatinase; KEGG: gur:Gura_1824 peptidase M24" /codon_start=1 /transl_table=11 /product="peptidase M24" /protein_id="ZP_05429322.1" /db_xref="GI:256004341" /db_xref="InterPro:IPR000587" /db_xref="InterPro:IPR000994" /db_xref="InterPro:IPR001131" /db_xref="InterPro:IPR001714" /translation="MENYMGKRLENFRAKLKEKGIDAAIIAKSPNYFYLSGFTGSFAY LVITRDDAVLVTDFRYREQARLEAPLFEVMEYSDNIYSFLNGILKSKNIEILGFEEDY ITYKKFKEFEEKFSVKELKPLEGMVEVMRMKKDKMELEIIKKAVEIADNAFSHILEFI KPGVREIEIAAELEYFMKKQGAKGTSFETIVASGVRSALPHGVASEKVIEHGDVVTMD FGAVFKGYCSDMTRTVFVGKPKEELVKIYNTVLTAQKAALEGAVKGLTGKKIDAVARE IIYREGFGFNFGHGLGHGVGIEIHEEPRLSPLGDVVMDDGMVVTVEPGIYVNGLGGVR IEDMIVINGDHPDVLTASKKDMIVL" misc_feature complement(1385..2461) /locus_tag="ClothDRAFT_1183" /note="Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006" /db_xref="CDD:30356" misc_feature complement(2066..2440) /locus_tag="ClothDRAFT_1183" /note="Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321" /db_xref="CDD:144790" misc_feature complement(1424..2047) /locus_tag="ClothDRAFT_1183" /note="Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092" /db_xref="CDD:29977" misc_feature complement(order(1454..1456,1496..1498,1583..1585, 1775..1777,1808..1810,1859..1861)) /locus_tag="ClothDRAFT_1183" /note="active site" /db_xref="CDD:29977" gene complement(2544..2972) /locus_tag="ClothDRAFT_1184" CDS complement(2544..2972) /locus_tag="ClothDRAFT_1184" /EC_number="4.2.1.10" /inference="protein motif:TFAM:TIGR01088" /note="KEGG: sun:SUN_1038 3-dehydroquinate dehydratase; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: dehydroquinase class II" /codon_start=1 /transl_table=11 /product="3-dehydroquinate dehydratase, type II" /protein_id="ZP_05429323.1" /db_xref="GI:256004342" /db_xref="InterPro:IPR001874" /translation="MKKVLVINGPNLNLLGIREKNIYGEETLEDIARKMNAEAEKLNV DLSFVQSNHEGEIIDKIHESRGKIDVIIINPGAYTHYSIAIRDAIKAVEIPTIELHLS NIHAREEFRSKSVIAPVCVGQISGFGSAGYILALHAALMI" misc_feature complement(2553..2966) /locus_tag="ClothDRAFT_1184" /note="Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466" /db_xref="CDD:63885" misc_feature complement(order(2640..2642,2700..2702,2709..2714, 2721..2723,2742..2744,2787..2789,2796..2798,2805..2819, 2934..2936,2940..2942)) /locus_tag="ClothDRAFT_1184" /note="trimer interface; other site" /db_xref="CDD:63885" misc_feature complement(order(2640..2642,2667..2675,2712..2714, 2733..2735,2742..2747,2751..2753,2904..2906,2919..2921)) /locus_tag="ClothDRAFT_1184" /note="active site" /db_xref="CDD:63885" misc_feature complement(order(2559..2561,2571..2573,2583..2585, 2592..2600,2604..2615,2619..2624,2655..2660,2664..2666)) /locus_tag="ClothDRAFT_1184" /note="dimer interface; other site" /db_xref="CDD:63885" gene complement(2950..3840) /locus_tag="ClothDRAFT_1185" CDS complement(2950..3840) /locus_tag="ClothDRAFT_1185" /inference="protein motif:PFAM:PF01261" /note="PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; KEGG: rpc:RPC_2669 xylose isomerase-like TIM barrel" /codon_start=1 /transl_table=11 /product="Xylose isomerase domain protein TIM barrel" /protein_id="ZP_05429324.1" /db_xref="GI:256004343" /db_xref="InterPro:IPR001719" /db_xref="InterPro:IPR012307" /translation="MIVLVRFGPSGNSESFYKEGHKSSAEMPAWLSGMGLDAYEYQCN RGVNIGKELAEKIGQEAQKYNIFLSIHAPYYINMASPEEEKRIKSKGYIIDCMRLAKW MGAKRIVVHTGSYSKVDKKWALEISAKLFDEVLKEADSLGLTDIVLCPEVLGKNNQIG SLEEIIEICKTNERLFPTIDFGHIHARGQGSLNTVEDFERIINMLENSLGTEKVRELH CHFSRIEFTKGGEKKHWNIDDTQFGPEFEHLAEVILKKNMNPVIICESRANMAEDALK LKKIYNKVAEGMQNEKSACN" misc_feature complement(3001..3741) /locus_tag="ClothDRAFT_1185" /note="AP endonuclease family 2; Region: AP2Ec; smart00518" /db_xref="CDD:128793" misc_feature complement(3004..3708) /locus_tag="ClothDRAFT_1185" /note="AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of D-arabino-6-...; Region: AP2Ec; cd00019" /db_xref="CDD:28903" misc_feature complement(order(3046..3048,3139..3141,3145..3147, 3187..3189,3292..3294,3301..3303,3388..3390,3508..3510, 3628..3630)) /locus_tag="ClothDRAFT_1185" /note="Metal-binding active site; metal-binding site" /db_xref="CDD:28903" misc_feature complement(order(3010..3012,3046..3048,3619..3621)) /locus_tag="ClothDRAFT_1185" /note="AP (apurinic/apyrimidinic) site pocket; other site" /db_xref="CDD:28903" gene complement(3953..4219) /locus_tag="ClothDRAFT_1186" CDS complement(3953..4219) /locus_tag="ClothDRAFT_1186" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429325.1" /db_xref="GI:256004344" /translation="MSQIKNYMEEVVFSLMKDVLSDINVCSCEKCRMDIAAIALNNLP PKYIVTDKGELYSKVDSLKQQFEVDVISALAKAAVIVKRNPRHE" misc_feature complement(3959..4210) /locus_tag="ClothDRAFT_1186" /note="Late competence development protein ComFB; Region: ComFB; pfam10719" /db_xref="CDD:151209" gene complement(4400..5245) /locus_tag="ClothDRAFT_1187" CDS complement(4400..5245) /locus_tag="ClothDRAFT_1187" /inference="protein motif:PFAM:PF06750" /note="PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; KEGG: ppd:Ppro_0982 prepilin peptidase" /codon_start=1 /transl_table=11 /product="peptidase A24A domain protein" /protein_id="ZP_05429326.1" /db_xref="GI:256004345" /db_xref="InterPro:IPR000045" /db_xref="InterPro:IPR010627" /db_xref="InterPro:IPR014032" /translation="MGTSLNLGLLFETGFTVFCYISVALLGLLVGSFLNVCIYRIPND ESVVRPRSHCMKCGHTLGALDLVPVFSYLFLKGRCRYCGEKISPRYALVELLTSVVYL LLFWKYGLAVDFLASAYLMSVLIAVFFIDLDHMIIPNKLVVAALVGGVLPFVYNIFRP MDIYVDRKWWNPLLGAFIGFGFLLLVAIVGYLVYKTDEAMGGGDVKLFAPIGLFLGWK MTIVALFISFVSAGIVSIVLLLLKKKERRSTFVFGPFIVMGTFFTYLFGWELLEWYLS TLLHV" misc_feature complement(4409..5188) /locus_tag="ClothDRAFT_1187" /note="Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989" /db_xref="CDD:32172" misc_feature complement(4916..5173) /locus_tag="ClothDRAFT_1187" /note="Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750" /db_xref="CDD:148386" misc_feature complement(4538..4894) /locus_tag="ClothDRAFT_1187" /note="Type IV leader peptidase family; Region: Peptidase_A24; cl02077" /db_xref="CDD:154734" gene complement(5331..7016) /locus_tag="ClothDRAFT_1188" CDS complement(5331..7016) /locus_tag="ClothDRAFT_1188" /inference="protein motif:PFAM:PF00437" /note="PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: geo:Geob_3374 type IV-A pilus assembly ATPase PilB" /codon_start=1 /transl_table=11 /product="type II secretion system protein E" /protein_id="ZP_05429327.1" /db_xref="GI:256004346" /db_xref="InterPro:IPR001482" /db_xref="InterPro:IPR007831" /translation="MQKQKRKGLGDILVEAGLISKEQLDKALKLQKKTGQKLGVLLVS EGIVTQEDIMRVLEEKIGVLRVALEECNIDPAVCSLIPEKLARRYELIPIAQKDGVLR VAMSDPLNVFAIDDIEDYTGMRVEPVVDFASSIKNAIDKYYRTQHVLVEPVKEKGILF KIDEETIELESVEAENESASMLLNSIIEQAIRNGSGDIHIEPLQNALKIRFRTDGQMH EVMRTEIGMLNGVLAKIKAICGMNMNEKAVPQDGRVKVSLDGRDYNLKVSILPTVFGE KIAIRIVHKKTSVIPKEQLGICQEDLVKFERMIKSPKGLVLITGPEGSGKTTTLYSAV SEINSPNVHIITIEDPVEYVIEGVNQVQVNMKTGLTYEKGLSSILEQGPDVIVIGDIK DAKTAEIAVKAAMGGHLVLGAFCANDTLDAVLTLVEMGIDPFFIASSLIGVISQRLVR KICPNCIKKYVATDEELSLLELDRPVELYSGNGCAECSGTGYKGKLGVFEVLNVDKSF RDMMKENFAKEKLRKFCVLRGMKTLKENAKQLVLEGKTTAFEMSRMLSFEEEL" misc_feature complement(5349..6995) /locus_tag="ClothDRAFT_1188" /note="type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538" /db_xref="CDD:162908" misc_feature complement(6576..6887) /locus_tag="ClothDRAFT_1188" /note="GSPII_E N-terminal domain; Region: GSPII_E_N; pfam05157" /db_xref="CDD:147371" misc_feature complement(5532..6317) /locus_tag="ClothDRAFT_1188" /note="PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129" /db_xref="CDD:29995" misc_feature complement(6036..6059) /locus_tag="ClothDRAFT_1188" /note="Walker A motif; other site" /db_xref="CDD:29995" misc_feature complement(order(5847..5852,5970..5975,5979..5981, 6036..6044,6054..6056)) /locus_tag="ClothDRAFT_1188" /note="ATP binding site; other site" /db_xref="CDD:29995" misc_feature complement(5847..5864) /locus_tag="ClothDRAFT_1188" /note="Walker B motif; other site" /db_xref="CDD:29995" gene complement(7112..8008) /locus_tag="ClothDRAFT_1189" CDS complement(7112..8008) /locus_tag="ClothDRAFT_1189" /EC_number="1.1.1.25" /inference="protein motif:TFAM:TIGR00507" /note="KEGG: kpe:KPK_4667 putative shikimate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase" /codon_start=1 /transl_table=11 /product="shikimate 5-dehydrogenase" /protein_id="ZP_05429328.1" /db_xref="GI:256004347" /db_xref="InterPro:IPR006151" /db_xref="InterPro:IPR011342" /db_xref="InterPro:IPR013708" /translation="MDIDVRVTGKTKLLGLVGNPVEHSISPQLHNTLSSLLGLDIVYI PLAVGKEDLETVVKALKALDFIGFNVTIPYKRDIMKYLDENSKEAILMGAVNTVKKID GRLYGYNTDAEGFLRSFKEEAGVGFKGKKVVLIGAGGVARAIAVKIASEDAEKISVVN RTVEKSVELAEVVNENIKEIVQVYNFEDKTFRMAFEESDIIINTTSVGMYPKTRETPV KFTECFNKNQIVYDVIYNPEKTKFLNDAEKRGAKIINGLGMLFYQGISAYEIWTGVKF TEDKLKSVYESFKKYLQLKSAK" misc_feature complement(7184..7987) /locus_tag="ClothDRAFT_1189" /note="shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258" /db_xref="CDD:178949" misc_feature complement(7715..7963) /locus_tag="ClothDRAFT_1189" /note="Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501" /db_xref="CDD:149523" misc_feature complement(7190..7681) /locus_tag="ClothDRAFT_1189" /note="NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065" /db_xref="CDD:133443" misc_feature complement(order(7220..7222,7229..7231,7304..7306, 7676..7678)) /locus_tag="ClothDRAFT_1189" /note="shikimate binding site; other site" /db_xref="CDD:133443" misc_feature complement(order(7229..7234,7241..7243,7310..7312, 7391..7399,7526..7531,7589..7591,7598..7600)) /locus_tag="ClothDRAFT_1189" /note="NAD(P) binding site; other site" /db_xref="CDD:133443" gene complement(8053..8556) /locus_tag="ClothDRAFT_1190" CDS complement(8053..8556) /locus_tag="ClothDRAFT_1190" /inference="protein motif:TFAM:TIGR01668" /note="TIGRFAM: HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: hypothetical protein ; K07015" /codon_start=1 /transl_table=11 /product="HAD superfamily (subfamily IIIA) phosphatase, TIGR01668" /protein_id="ZP_05429329.1" /db_xref="GI:256004348" /db_xref="InterPro:IPR006549" /db_xref="InterPro:IPR010021" /translation="MLEKFYPDLQADRVQDIDLDFLAEKNIKGLILDIDNTLVPEHVE EADENTIAWIDKVKKKGFKVCIVSNASEKRVARFNSKLNVDVIHRASKPRSRSFVKAM EIMNTKASETAVIGDQIFTDIYGGNKVNMFTILVTPIDKREYFFVRLKRIAEKFVLAK MKTRKQI" misc_feature complement(8149..8469) /locus_tag="ClothDRAFT_1190" /note="Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others...; Region: HAD_like; cd01427" /db_xref="CDD:119389" misc_feature complement(order(8350..8355,8452..8460)) /locus_tag="ClothDRAFT_1190" /note="active site" /db_xref="CDD:119389" misc_feature complement(8443..8460) /locus_tag="ClothDRAFT_1190" /note="motif I; other site" /db_xref="CDD:119389" misc_feature complement(8353..8355) /locus_tag="ClothDRAFT_1190" /note="motif II; other site" /db_xref="CDD:119389" gene 8856..9926 /locus_tag="ClothDRAFT_1191" CDS 8856..9926 /locus_tag="ClothDRAFT_1191" /inference="protein motif:TFAM:TIGR01123" /note="TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; KEGG: dat:HRM2_10750 branched-chain amino acid aminotransferase" /codon_start=1 /transl_table=11 /product="branched-chain amino acid aminotransferase" /protein_id="ZP_05429330.1" /db_xref="GI:256004349" /db_xref="InterPro:IPR001544" /db_xref="InterPro:IPR005786" /translation="MSYQISIQKTQNPKNKPDQDNLGFGQIFTDHMFIMDYTEGKGWH DPRIVPYGPLSLEPSTMVFHYGQAVFEGLKAYKTEDGRILLFRPRKNMERINISNERV CIPKIDVDFAVEACKTLVSVDRDWIPEAEGTSLYIRPFIISTDPFLGVRPSWTYKFII ILSPVGAYYKEGINPVKIYVESEYVRAVKGGTGYAKTPGNYAASLIAQVKAKELGYTQ VLWLDGVEKKYIEEVGTMNVFFKINGEVITPSLDGSILAGITRESTIELLRASGIKVT ERKITIEEIYNAHEAGTLEEAFGTGTAAVISPIGELSWNGKVIKINDGKIGETASFVY NTITGIQSGKIEDKFGWTVEVK" misc_feature 8856..9923 /locus_tag="ClothDRAFT_1191" /note="branched-chain amino acid aminotransferase; Provisional; Region: PRK13357" /db_xref="CDD:183996" misc_feature 9018..9884 /locus_tag="ClothDRAFT_1191" /note="BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-...; Region: BCAT_beta_family; cd01557" /db_xref="CDD:29568" misc_feature order(9018..9032,9039..9053,9057..9059,9063..9065, 9156..9158,9267..9269,9273..9275,9291..9299,9309..9311, 9330..9332,9447..9449,9462..9464,9468..9470,9480..9482, 9522..9524) /locus_tag="ClothDRAFT_1191" /note="homodimer interface; other site" /db_xref="CDD:29568" misc_feature order(9048..9050,9063..9065,9135..9137,9303..9305, 9441..9443,9456..9458,9549..9551,9630..9635,9759..9761) /locus_tag="ClothDRAFT_1191" /note="substrate-cofactor binding pocket; other site" /db_xref="CDD:29568" misc_feature 9441..9443 /locus_tag="ClothDRAFT_1191" /note="catalytic residue; other site" /db_xref="CDD:29568" gene 10216..10707 /locus_tag="ClothDRAFT_1192" CDS 10216..10707 /locus_tag="ClothDRAFT_1192" /inference="protein motif:PFAM:PF01957" /note="PFAM: protein of unknown function DUF107; KEGG: scl:sce5335 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF107" /protein_id="ZP_05429331.1" /db_xref="GI:256004350" /db_xref="InterPro:IPR002810" /translation="MFDFVHNIDIWAAISFILGFIFVIIEMFFPGFGLPGVVGLIFLF IGIVLTAKTLTDVLVLLAIILLILAVVLAIAVRSASKGRLKKLVLTDSLEKESGFEGT EDFTSFLGKEGVALTALRPAGTAEFDGVKLDVVSEFDFIEKDAKVKIVKVEGRRIVVR KID" misc_feature <10237..10704 /locus_tag="ClothDRAFT_1192" /note="Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030" /db_xref="CDD:31233" misc_feature <10531..10704 /locus_tag="ClothDRAFT_1192" /note="NfeD-like; Region: NfeD; cl00686" /db_xref="CDD:120037" gene 10810..11799 /locus_tag="ClothDRAFT_1193" CDS 10810..11799 /locus_tag="ClothDRAFT_1193" /inference="similar to AA sequence:KEGG:Dole_0018" /note="KEGG: dol:Dole_0018 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429332.1" /db_xref="GI:256004351" /translation="MDGIAFILIVGAIIVFISLFFAIVPVGLWISAFAANVRVSIFTL IGMRLRRVVPSRVINPLIKATKAGINVSINKLEAHYLAGGNVDRVVNALIAAQRANIP LEFERAAAIDLAGRNVLEAVQMSVNPKVIETPVVAAIAKDGIELRAKARVTVRANIDR LVGGAGEQTIIARVGEGVVTTVGSATDHKQVLENPDAISKTVLSKGLDAGTAFEILSI DIADIDVGRNVGAQLQTDQAEADKRIAQAKAEERRAMAVAREQEMKAMVQEMRAKVVE AEAEVPKALAAALREGKIGVLDYYHLQNLIADTQMRDSISKMSKHDDSSSDKK" misc_feature 10810..11745 /locus_tag="ClothDRAFT_1193" /note="Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4864" /db_xref="CDD:34473" misc_feature 10810..11745 /locus_tag="ClothDRAFT_1193" /note="SigmaW regulon antibacterial; Region: YdfA_immunity; cl12057" /db_xref="CDD:187175" gene 11854..12399 /locus_tag="ClothDRAFT_1194" CDS 11854..12399 /locus_tag="ClothDRAFT_1194" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: GD17302 gene product from transcript GD17302-RA" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429333.1" /db_xref="GI:256004352" /translation="MSMNKDLLLSLLETLAEQSKNANNTKMRQYNTANKNPHNYSTRP VQRASHNSGAHAKPRPNVSHVAKEHYFEGSHNLEESSDFEGIGQGSLDYASSEGVGQG SLDYTSSEGKPGFQGSPGLEGSLSSEGDGRHSKNNIVTPETPSQTASFNLSEISKNDI VRGIILSEILSKPKALRRNQW" gene complement(12416..13135) /locus_tag="ClothDRAFT_1195" CDS complement(12416..13135) /locus_tag="ClothDRAFT_1195" /inference="protein motif:PFAM:PF02915" /note="PFAM: Rubrerythrin; KEGG: dal:Dalk_2366 rubrerythrin" /codon_start=1 /transl_table=11 /product="Rubrerythrin" /protein_id="ZP_05429334.1" /db_xref="GI:256004353" /db_xref="InterPro:IPR003251" /db_xref="InterPro:IPR009040" /translation="MKSLKNTKTMENLMKAFAGESQARTRYNFYASVANKEGYRQIEA IFNETADNEKEHAKRFYKFLLEGLNGELPASIMINADYPVAYGNTLDNLKAAAAGENE EWTKLYPEFAKVAKEEGFDEIAAAFTKIAEVEQRHEARYKKLAENIENNKVFNKDEKV LWKCRNCGYVHEGNSAPENVRHVLIQKHFSKCWQKIINLCILKFILSLKYISSVAKTS KSGNFTRICFCILRTKKFLTS" misc_feature complement(12602..13123) /locus_tag="ClothDRAFT_1195" /note="Rubrerythrin [Energy production and conversion]; Region: COG1592" /db_xref="CDD:31780" misc_feature complement(12689..13114) /locus_tag="ClothDRAFT_1195" /note="Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041" /db_xref="CDD:153100" misc_feature complement(order(12725..12727,12734..12736,12827..12829, 12836..12841,12968..12970,12977..12979,13055..13057, 13067..13069,13076..13078)) /locus_tag="ClothDRAFT_1195" /note="binuclear metal center; other site" /db_xref="CDD:153100" misc_feature complement(<12599..12658) /locus_tag="ClothDRAFT_1195" /note="Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected...; Region: rubredoxin_like; cl00202" /db_xref="CDD:185824" misc_feature complement(order(12635..12637,12644..12646)) /locus_tag="ClothDRAFT_1195" /note="iron binding site; other site" /db_xref="CDD:29431" gene 13418..14554 /locus_tag="ClothDRAFT_1196" CDS 13418..14554 /locus_tag="ClothDRAFT_1196" /inference="protein motif:TFAM:TIGR00350" /note="TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="cell envelope-related transcriptional attenuator" /protein_id="ZP_05429335.1" /db_xref="GI:256004354" /db_xref="InterPro:IPR002195" /db_xref="InterPro:IPR004474" /translation="MGQKKIFSKKKNLTFKKALLIWMVSLIVLGGMIFLLGKFVLSDS NGSSDVDNDLTYPPVKSYEPISFPTPGKIGNDKPSDEENSDKFQGLTNGMKYHEKLVD ESSRNILFIGQDRISGLYDTIGILSIDRKNKKLKIIMIPRDLYIDYSSRVKHYLEENG RLNDPDFYKINAAHLIGPYMKYEGKFGAYSMNFLAELIKEIFDIEVHDYVRVNTEGFV QIVDLFGGVDINVPYDMHYDDIYQDLHIHINKGWNHLDGKKAEGFVRYRQSNDEMGNI THSIGDYERKKNQINFIKAFIEQHGTMSNIDKLPSLISTLNKYMKHSIGVGDVLTTYI GYAKDVVLYKYPIETYTVTGKDKYMNQRYYIVIENDNKTSKVVD" sig_peptide 13418..13546 /locus_tag="ClothDRAFT_1196" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.657 at residue 43" misc_feature 13736..14539 /locus_tag="ClothDRAFT_1196" /note="Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581" /db_xref="CDD:186090" gene 14729..15049 /locus_tag="ClothDRAFT_1197" CDS 14729..15049 /locus_tag="ClothDRAFT_1197" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429336.1" /db_xref="GI:256004355" /translation="MYPHIHRYKFESKNTNRHNHKIIGYTDNMIGIEAFHIHAYYGIS SYNGHTHYFSGFTGLPIKTENGHIHRIEGILESASDHEHVYRNYTDENIEYISHSILK HAYV" gene 15282..17399 /locus_tag="ClothDRAFT_1198" CDS 15282..17399 /locus_tag="ClothDRAFT_1198" /inference="protein motif:PFAM:PF00120" /note="PFAM: glutamine synthetase catalytic region; KEGG: ppd:Ppro_1682 glutamine synthetase, catalytic region" /codon_start=1 /transl_table=11 /product="glutamine synthetase catalytic region" /protein_id="ZP_05429337.1" /db_xref="GI:256004356" /db_xref="InterPro:IPR008146" /translation="MVNDELQTYSLTEVFGANVFNDAAMRERLPKPAYKALKKTIDEG TPLDRDIAEIVANAMKDWAIDKGATHYTHWFQPMTGITAEKHDSFISPTSDGKVIMEF SGKELIKGESDASSFPSGGLRATFEARGYTAWDCTSPAFVKDNTLYIPTVFCSYNGEV LDKKTPLLRSMEALSKQALRILRLLGNTTVKKVITTVGAEQEYFLIDKKLHDQRKDLI YTGRTLFGAMPPKGQEMDDHYYGAFKERISAFMKELDRELWKLGVSAKTKHNEVAPAQ HELAPIFNTANIATDHNQLIMDTLKKVAQRHGLVCLLHEKPFAGLNGSGKHNNWSLST DDGQNLLDPGRTPHENAQFLIFLCAVIKAVDEYADLLRCAAANAGNDHRLGAHEAPPA IISIFLGEQLTDILEQIENNGGAKSLKQAAPLKIGVTTLPVLPKDATDRNRTSPFAFT GNKFEFRMVPSSASIAGPIFVLNTIVAEELCQIADRLEKAEDLNAEIHAVLREIVKNH KRIIFNGNNYSEEWIEEAKRRGLPNIRSTVEAIKALIDEKNIRVFEKHKVLNRTELYS RYEILLESYIKTINIEALTMIEMTKRDIIPAVIGYITKLADSINTVKATGVNADTSVQ AELLQEVSSLLAELKKNLAALEKSTSEAADFSGDTYKKACMYRDDVFVRMNELRAVAD KLETLVDSKMWPFPTYGDLLFNV" misc_feature 15309..15791 /locus_tag="ClothDRAFT_1198" /note="Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437" /db_xref="CDD:152871" misc_feature 15312..17396 /locus_tag="ClothDRAFT_1198" /note="Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968" /db_xref="CDD:33749" misc_feature 15870..16532 /locus_tag="ClothDRAFT_1198" /note="Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120" /db_xref="CDD:143894" gene complement(17592..18137) /locus_tag="ClothDRAFT_1199" CDS complement(17592..18137) /locus_tag="ClothDRAFT_1199" /inference="protein motif:PFAM:PF01558" /note="PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dde:Dde_0046 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit" /codon_start=1 /transl_table=11 /product="pyruvate ferredoxin/flavodoxin oxidoreductase" /protein_id="ZP_05429338.1" /db_xref="GI:256004357" /db_xref="InterPro:IPR002869" /translation="MKMADQQIIMAGFGGQGILSAGRILAYAGMLENKNVSWLPSYGP EMRGGTANCNVIISDDVIGSPILNSATTLIVMNGPSLDKFESYVESGGIIIKDSSLVQ REPARTDVKVYGVPATETAFKMGNPTFANIILLGKLIALTNIVSKENFEIALRKTLPS KKHNLIPEEMKALEFGMQYEC" misc_feature complement(17601..18131) /locus_tag="ClothDRAFT_1199" /note="Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546" /db_xref="CDD:186072" misc_feature complement(17601..18119) /locus_tag="ClothDRAFT_1199" /note="2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537" /db_xref="CDD:181462" gene complement(18138..18884) /locus_tag="ClothDRAFT_1200" CDS complement(18138..18884) /locus_tag="ClothDRAFT_1200" /inference="protein motif:PFAM:PF02775" /note="PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: dat:HRM2_10700 keto/isovalerate ferredoxin oxidoreductase, beta subunit" /codon_start=1 /transl_table=11 /product="thiamine pyrophosphate protein domain protein TPP-binding" /protein_id="ZP_05429339.1" /db_xref="GI:256004358" /db_xref="InterPro:IPR011766" /translation="MNAVFKKPHALVDVSMHYCPGCTHGIVHRLIAEVIDELDIEGKT IGVSPVGCAYNNYEYFNCDMIQAAHGRAPAVATGAKRVNPDNVVFAYQGDGDLAAIGT AEIVHAATRGEKITVIFINNAIYGMTSGQMAPTTLIDQVTTTTPFGRKPEVHGYPINV CELLSTLEGAVYVERVSVHDIKNIMNAKKAIKKAFKVQMANLGFSIVEVLSSCPTNWG LSPVEALKWIEEKMIPVYPLGNYKGKDLEV" misc_feature complement(18237..18833) /locus_tag="ClothDRAFT_1200" /note="Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375" /db_xref="CDD:73355" misc_feature complement(order(18513..18515,18519..18521,18597..18608, 18678..18680)) /locus_tag="ClothDRAFT_1200" /note="TPP-binding site; other site" /db_xref="CDD:73355" gene complement(18935..19993) /locus_tag="ClothDRAFT_1201" CDS complement(18935..19993) /locus_tag="ClothDRAFT_1201" /inference="protein motif:PFAM:PF01855" /note="PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sfu:Sfum_0301 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein" /codon_start=1 /transl_table=11 /product="pyruvate flavodoxin/ferredoxin oxidoreductase domain protein" /protein_id="ZP_05429340.1" /db_xref="GI:256004359" /db_xref="InterPro:IPR002880" /translation="MGEKLLMKGNEAIAEAALRAGCRHYFGYPITPQTEIAHYLAKKM PEVGGTFIQAESEVAAINMVYGAASAGARVLTSSSSPGISLKQEGLSYLAGAELPAVV VNIVRCGPGLGGILPAQGDYFQAVKGGGHGDYKMVVLAPSSVQELYELTVEAFNIADR YRIVSMIMGDGILGQMMEAVEFKDVENIEKIDKPWATTGTQMKREHNTITSIYIQPEV LEKHNQKLQAKYRLIEERETRVESYNCENADIIVTAFGTVARIVKNVIKMAEKEGIKV GLIRPITLWPFPTKEYEKYADVPKAFLTVELNAGQMVEDVRLAVNGKKPVYFHGRMGG MIPTQKEILDKIKEILNN" misc_feature complement(18944..19993) /locus_tag="ClothDRAFT_1201" /note="2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119" /db_xref="CDD:180853" misc_feature complement(19481..19969) /locus_tag="ClothDRAFT_1201" /note="Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034" /db_xref="CDD:132917" misc_feature complement(order(19613..19618,19664..19669,19706..19708, 19718..19720,19727..19729,19778..19780,19784..19786, 19793..19801,19805..19810,19829..19840,19880..19882, 19889..19891,19901..19903,19919..19924)) /locus_tag="ClothDRAFT_1201" /note="dimer interface; other site" /db_xref="CDD:132917" misc_feature complement(order(19718..19720,19727..19729,19778..19780, 19784..19786,19793..19801,19805..19810,19829..19840, 19880..19885,19901..19903,19907..19912,19919..19924)) /locus_tag="ClothDRAFT_1201" /note="PYR/PP interface; other site" /db_xref="CDD:132917" misc_feature complement(order(19823..19825,19907..19909)) /locus_tag="ClothDRAFT_1201" /note="TPP binding site; other site" /db_xref="CDD:132917" misc_feature complement(order(19673..19675,19901..19903)) /locus_tag="ClothDRAFT_1201" /note="substrate binding site; other site" /db_xref="CDD:132917" misc_feature complement(<19076..19261) /locus_tag="ClothDRAFT_1201" /note="Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780" /db_xref="CDD:145764" gene complement(20044..20250) /locus_tag="ClothDRAFT_1202" CDS complement(20044..20250) /locus_tag="ClothDRAFT_1202" /inference="protein motif:PFAM:PF00037" /note="PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gur:Gura_2240 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein" /codon_start=1 /transl_table=11 /product="4Fe-4S ferredoxin iron-sulfur binding domain protein" /protein_id="ZP_05429341.1" /db_xref="GI:256004360" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR017900" /translation="MAKVIFDENRCKGCKLCTTVCPKKIVVMNEDKLNQKGFHPAGVV DMDKCIGCAFCATICPDCVIEVYK" misc_feature complement(<20071..>20226) /locus_tag="ClothDRAFT_1202" /note="The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved alpha-; Region: HCP_like; cl14655" /db_xref="CDD:187409" gene complement(20263..20973) /locus_tag="ClothDRAFT_1203" CDS complement(20263..20973) /locus_tag="ClothDRAFT_1203" /inference="protein motif:PFAM:PF07238" /note="PFAM: type IV pilus assembly PilZ" /codon_start=1 /transl_table=11 /product="type IV pilus assembly PilZ" /protein_id="ZP_05429342.1" /db_xref="GI:256004361" /db_xref="InterPro:IPR009875" /translation="MSKIKLRDFLSEGAIIRTKHCNSTNWVTNVVYAINEDWIEVDIG LEKDYIDNIIMIGDTMRCKYSTDEYEFMLIGWVTKIKLEEPQSITIKIHDVERFANRR DNYRYDIYLCSVIKANRNDEKGVFAIMTNLSQGGAAFIAKEDIEKELETAYNMQEEKN YYFEVFITPKKQLCFTGTVKRKTSNEKGFEYGVKIFDIDFQNEKTLNELLDELEKKDK EFYNKRSSFWSKNSKYNK" misc_feature complement(20371..20676) /locus_tag="ClothDRAFT_1203" /note="PilZ domain; Region: PilZ; cl01260" /db_xref="CDD:163963" gene complement(20987..21655) /locus_tag="ClothDRAFT_1204" CDS complement(20987..21655) /locus_tag="ClothDRAFT_1204" /inference="similar to AA sequence:KEGG:Dalk_2229" /note="KEGG: dal:Dalk_2229 putative ATP/GTP-binding protein" /codon_start=1 /transl_table=11 /product="putative ATP/GTP-binding protein" /protein_id="ZP_05429343.1" /db_xref="GI:256004362" /translation="MFGKRISIFTGHFGSGKTEVAVNFALKLRERNIKTAIVDFDIVN PFFRAVDAKEHLESKGVWVISSLYANTNVDIPALPAEIYTLFEKKEYNVVFDVGGDDL GARALSRFKQEIESEDYEMYFVINTKRPMTDTAEKIEEMIFEIESASRLKVSKLVNNT NLVGQTTVEDVLEGHRMIKELSQKLDIPIAFVSGFREIADEVRKIENTEVLYLDGLIK LPWD" misc_feature complement(21380..21616) /locus_tag="ClothDRAFT_1204" /note="Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras...; Region: Ras_like_GTPase; cl10444" /db_xref="CDD:186996" gene complement(21772..21942) /locus_tag="ClothDRAFT_1205" CDS complement(21772..21942) /locus_tag="ClothDRAFT_1205" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429344.1" /db_xref="GI:256004363" /translation="MSVRKQEPELRKFLIIALLKIEYKHYMKDYNDVGGIPPVFIETG CRVAIQNCNKNT" gene complement(21917..22504) /locus_tag="ClothDRAFT_1206" CDS complement(21917..22504) /locus_tag="ClothDRAFT_1206" /inference="protein motif:PFAM:PF03358" /note="PFAM: NADPH-dependent FMN reductase; KEGG: dps:DP1259 iron-sulfur flavoprotein" /codon_start=1 /transl_table=11 /product="NADPH-dependent FMN reductase" /protein_id="ZP_05429345.1" /db_xref="GI:256004364" /db_xref="InterPro:IPR005025" /translation="MLIVGINGSPKKEGNTKYLINTVLEEAKSQGVETMVLEVGELLN SVKNPFCVVCSNPCSGICYKGTKLEEAYEILKKADAIVMGSPVYFGSVSAQLKAFFDK TRKLRSEKALYNKFACGVTVGGARFGGQETTMKALHDIMLVHGMTIVGDGYVGDDCGH HGVCAQQPADKDEFAIKRAKILGRRLVDVCKKAGA" misc_feature complement(22025..22504) /locus_tag="ClothDRAFT_1206" /note="NADPH-dependent FMN reductase; Region: FMN_red; cl00438" /db_xref="CDD:185997" gene complement(22598..23254) /locus_tag="ClothDRAFT_1207" CDS complement(22598..23254) /locus_tag="ClothDRAFT_1207" /EC_number="5.3.1.24" /inference="protein motif:PRIAM:5.3.1.24" /note="PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: glo:Glov_1212 N-(5'-phosphoribosyl)anthranilate isomerase" /codon_start=1 /transl_table=11 /product="Phosphoribosylanthranilate isomerase" /protein_id="ZP_05429346.1" /db_xref="GI:256004365" /db_xref="InterPro:IPR001240" /translation="MTCVKICGLRRKEDIDYVNLYKPQFAGFVFAESRRKVSKETARM LVKALLPQIKSVGIFVNEKKETVAEIVKYTGLDCVQLHGDETPEYVEKLKELLGRITE KRIEIWKAVRVKNKESLEIISEFDVDAFLLDAYVEGSYGGAGAVFDWQLAADVAAGHE RIILAGGLNPENVKTAVAKVKPYGVDVSSGVETDGFKDAEKIRDFIMKVREADGGVLS " misc_feature complement(22628..23245) /locus_tag="ClothDRAFT_1207" /note="Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric...; Region: PRAI; cd00405" /db_xref="CDD:73365" misc_feature complement(order(22688..22693,22697..22699,22856..22858, 23009..23011,23015..23017,23168..23170,23234..23236, 23240..23242)) /locus_tag="ClothDRAFT_1207" /note="active site" /db_xref="CDD:73365" gene complement(23258..23989) /locus_tag="ClothDRAFT_1208" CDS complement(23258..23989) /locus_tag="ClothDRAFT_1208" /EC_number="4.1.1.48" /inference="protein motif:PRIAM:4.1.1.48" /note="PFAM: Indole-3-glycerol phosphate synthase; KEGG: pol:Bpro_4451 indole-3-glycerol-phosphate synthase" /codon_start=1 /transl_table=11 /product="Indole-3-glycerol-phosphate synthase" /protein_id="ZP_05429347.1" /db_xref="GI:256004366" /db_xref="InterPro:IPR001468" /db_xref="InterPro:IPR013798" /translation="MSRITIEGWKQKIKRPGIHKPLDFYGALKNNGDISIIAEVKKAS PSKGIIKEDFDPLKIAKEYVESDIQAISVLTERNFFKGDEDYLVKIRQFCPLPILRKD FIIDLWQIYESRYIGADAILLIVSLLSDEELKKFQIVANILGMQCLVEVHDERELERA LESGARIIGINNRDLRTFEVDLKNTEKLMNRIPNDRVVVSESGIKDTEDLKYLKELGV DAVLIGETFMRARSISEKIREFKAV" misc_feature complement(23270..23920) /locus_tag="ClothDRAFT_1208" /note="Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331" /db_xref="CDD:73363" misc_feature complement(order(23315..23320,23381..23386,23465..23467, 23471..23473,23477..23479,23540..23542,23618..23620, 23681..23683,23687..23689,23750..23752,23852..23860, 23867..23869,23873..23875)) /locus_tag="ClothDRAFT_1208" /note="active site" /db_xref="CDD:73363" misc_feature complement(order(23477..23479,23540..23542,23687..23689, 23867..23869,23873..23875)) /locus_tag="ClothDRAFT_1208" /note="ribulose/triose binding site; other site" /db_xref="CDD:73363" misc_feature complement(order(23315..23320,23381..23383,23867..23869)) /locus_tag="ClothDRAFT_1208" /note="phosphate binding site; other site" /db_xref="CDD:73363" misc_feature complement(order(23465..23467,23471..23473,23750..23752, 23855..23857)) /locus_tag="ClothDRAFT_1208" /note="substrate (anthranilate) binding pocket; other site" /db_xref="CDD:73363" misc_feature complement(order(23465..23467,23618..23620,23681..23683, 23687..23689,23750..23752)) /locus_tag="ClothDRAFT_1208" /note="product (indole) binding pocket; other site" /db_xref="CDD:73363" gene complement(24105..25142) /locus_tag="ClothDRAFT_1209" CDS complement(24105..25142) /locus_tag="ClothDRAFT_1209" /inference="protein motif:TFAM:TIGR01245" /note="TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; KEGG: sat:SYN_01945 anthranilate phosphoribosyltransferase" /codon_start=1 /transl_table=11 /product="anthranilate phosphoribosyltransferase" /protein_id="ZP_05429348.1" /db_xref="GI:256004367" /db_xref="InterPro:IPR000312" /db_xref="InterPro:IPR005940" /db_xref="InterPro:IPR017459" /translation="MLKKAISKLVEGKNLSESEIIEALDCIMEGKATPAQIGSFITAL RIKGETIEEITGCAKVMRAKADKICPNVDYYIDTCGTGGDGTNTFNISTATAFVAAAG GVYVAKHGNRSVSSKSGSADVLEALGVNIDLDPVQVKECIEKVGIGFIYAPVFHKSMK HAAGPRKELGIRTIFNILGPLTNPSNAKGQVLGVFNPNLTELMANVLLNLGIERAMVI HGMDGMDEITTTTSTKVSEVRNNEVITYELFPENYGIALASPEDLTGGNAEENAQIIR RIFNGEKGPKRDIVVLNSAAALYVGKVVSSIEEGIGLAEEVIDSGKALQKLDEFVEFT NSFISYNEMSG" misc_feature complement(24129..25142) /locus_tag="ClothDRAFT_1209" /note="anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188" /db_xref="CDD:178920" misc_feature complement(24945..25142) /locus_tag="ClothDRAFT_1209" /note="Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885" /db_xref="CDD:145834" misc_feature complement(24171..24878) /locus_tag="ClothDRAFT_1209" /note="Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591" /db_xref="CDD:144256" gene complement(25217..25807) /locus_tag="ClothDRAFT_1210" CDS complement(25217..25807) /locus_tag="ClothDRAFT_1210" /inference="protein motif:TFAM:TIGR00566" /note="TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: sat:SYN_01946 anthranilate synthase component II" /codon_start=1 /transl_table=11 /product="glutamine amidotransferase of anthranilate synthase" /protein_id="ZP_05429349.1" /db_xref="GI:256004368" /db_xref="InterPro:IPR000991" /db_xref="InterPro:IPR001317" /db_xref="InterPro:IPR006220" /db_xref="InterPro:IPR006221" /db_xref="InterPro:IPR011702" /translation="MIENILIIDNYDSFTYNLYQYVGEISPNIEVYRNDKITLEKIEE MNPTHIIISPGPGFPKDAGICIEAIRKFGRYIPILGVCLGHQAIGEAFGGKVVHAKEL MHGKASEVEIDRECLIFRNLPEKIRVGRYHSLIVQKEGLPECLKITAVTQDGEIMGLM HKSFPVFGIQFHPESILTPEGKAILKNFINIKRVAI" misc_feature complement(25238..25795) /locus_tag="ClothDRAFT_1210" /note="para-aminobenzoate synthase component II; Provisional; Region: PRK08857" /db_xref="CDD:181566" misc_feature complement(25241..25795) /locus_tag="ClothDRAFT_1210" /note="Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743" /db_xref="CDD:153214" misc_feature complement(order(25406..25417,25550..25552,25559..25564, 25637..25639,25643..25648)) /locus_tag="ClothDRAFT_1210" /note="glutamine binding; other site" /db_xref="CDD:153214" misc_feature complement(order(25286..25288,25292..25294,25562..25564)) /locus_tag="ClothDRAFT_1210" /note="catalytic triad; other site" /db_xref="CDD:153214" gene complement(25804..27288) /locus_tag="ClothDRAFT_1211" CDS complement(25804..27288) /locus_tag="ClothDRAFT_1211" /EC_number="4.1.3.27" /inference="protein motif:TFAM:TIGR00564" /note="KEGG: gur:Gura_1731 anthranilate synthase component I; TIGRFAM: anthranilate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein" /codon_start=1 /transl_table=11 /product="anthranilate synthase component I" /protein_id="ZP_05429350.1" /db_xref="GI:256004369" /db_xref="InterPro:IPR005256" /db_xref="InterPro:IPR005801" /db_xref="InterPro:IPR006805" /db_xref="InterPro:IPR015890" /translation="MFYPTLDEVKIMAKDYNIIPVTMEVYADMETPISLFKRFEESSC CFLLESVEGGEKWARYSIIGKNPFLVVESYKNKTIIRERNGSQREVEGNPVEIIKGIM GKFKGANLPNLPRFNGGAVGYFGYDLIRHYENLPNVPEDDMGLPECHFMFTDEVLVYD HLKQKIHIIVNLHVNGNIERAYISAVDRIKTIHREILDTRWKTADNSVLSYNKKKNEL AVTSNISKEDFCRNVLKAKQYIRDGDIFQVVLSQRLCVETNENPFNIYRALRVINPSP YMYYLKFGGYRIIGSSPEMLVRVENGIVETCPIAGTRKRGRTKEEDEALEKELLSDEK EIAEHVMLVDLGRNDIGRVSKFGTVAVKNLMHIERYSHVMHVVTNVQGEIREDKTPFD ALMSILPAGTLSGAPKVRAMEIIDELETVKRGPYGGAIGYLSFNGNLDSCITIRTIIL KDGKAYVQAGAGIVADSVPEREYEECYNKAMALLKAIEEAGEIR" misc_feature complement(25825..27210) /locus_tag="ClothDRAFT_1211" /note="anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564" /db_xref="CDD:161932" misc_feature complement(26785..27207) /locus_tag="ClothDRAFT_1211" /note="Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715" /db_xref="CDD:147064" misc_feature complement(25897..26616) /locus_tag="ClothDRAFT_1211" /note="chorismate binding enzyme; Region: Chorismate_bind; cl10555" /db_xref="CDD:187007" gene 27782..29074 /locus_tag="ClothDRAFT_1212" CDS 27782..29074 /locus_tag="ClothDRAFT_1212" /inference="similar to AA sequence:KEGG:Nmul_A0278" /note="KEGG: nmu:Nmul_A0278 glycosyl transferase family protein" /codon_start=1 /transl_table=11 /product="glycosyl transferase family protein" /protein_id="ZP_05429351.1" /db_xref="GI:256004370" /translation="MISRFIDYIKKNKYLVIIFIGVILRLVWIFAMPTYPETDFMWYH VKGKEIAEGKGFLNGIYPYYTGRPGFPTAFRPIGYPGTLAILYFIFGAHFIVAKLFNI VLSTLIMFLTYKLADKFFGNKIALLTLLLYALSPLAIAYNSIICSEILFSALLMLSVY LFFNKNNPLLIGLLIGYLTLVRPIGVFIPSIFVLYEFIRKDVGLKHKIKYVAVFAVAV GLVIAPWIIRNYIVFGEPIFSTNGGYVFYVNNNDYATGSWSDPFKYPDSPMLKYKTED GFDELAIHKLGKQLAREWIKKNPKRFIELAFLRIANSYWFKTEDIMWAFTIGINQWHP VTSKAVKLQKLLYRPFYIVLFIFIIYALIRFIRQRKIDFTTFILLIFLYFNAMMFVLE GNSRYVFPLHPIYTIGVSFVIYNVLKKLLPERFSAVLS" gene 29223..30317 /locus_tag="ClothDRAFT_1213" CDS 29223..30317 /locus_tag="ClothDRAFT_1213" /inference="protein motif:TFAM:TIGR00092" /note="TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; GTP-binding protein HSR1-related; KEGG: pca:Pcar_2000 translation-associated GTPase" /codon_start=1 /transl_table=11 /product="GTP-binding protein YchF" /protein_id="ZP_05429352.1" /db_xref="GI:256004371" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR004396" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR013029" /translation="MKMGIVGLPNVGKSTLFNAITKAGAESANYPFCTIEPNVGIVAV PDERLNKLAEMYKPEKVTPTTIEFVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHVV RCFEDSNIVHVEGSVDPVRDVETIEMELILADMEVLERRIDRTRKMLKSGDKKYQVEL DIYERIMKTFEEGKPVRSMSFSEEEKKIVDQLFLLTSKPVLYAANVSEDDINSDKPNP LVEKLVNYAKNEGSEVMVICAKIEEEIAQLDDEEKAEFLKELGLSESGLDRLIKASYR LLGLISFLTAGPQEVRAWTIVKGTKAPQAAGKIHSDFEKGFIRAEVVAYDDLIKAGSY TIAKEKGLVRSEGKDYVMQDGDVTLFRFNV" misc_feature 29223..30314 /locus_tag="ClothDRAFT_1213" /note="GTP-binding protein YchF; Reviewed; Region: PRK09601" /db_xref="CDD:181981" misc_feature 29229..30056 /locus_tag="ClothDRAFT_1213" /note="YchF subfamily. YchF is a member of the Obg family, which includes four other subfamilies of GTPases: Obg, DRG, Ygr210, and NOG1. Obg is an essential gene that is involved in DNA replication in C. crescentus and Streptomyces griseus and is associated...; Region: YchF; cd01900" /db_xref="CDD:133300" misc_feature 29241..29264 /locus_tag="ClothDRAFT_1213" /note="G1 box; other site" /db_xref="CDD:133300" misc_feature order(29250..29252,29256..29267,29835..29840,29844..29846, 29934..29942) /locus_tag="ClothDRAFT_1213" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133300" misc_feature 29310..29333 /locus_tag="ClothDRAFT_1213" /note="Switch I region; other site" /db_xref="CDD:133300" misc_feature 29322..29324 /locus_tag="ClothDRAFT_1213" /note="G2 box; other site" /db_xref="CDD:133300" misc_feature order(29427..29456,29475..29504) /locus_tag="ClothDRAFT_1213" /note="Switch II region; other site" /db_xref="CDD:133300" misc_feature 29430..29441 /locus_tag="ClothDRAFT_1213" /note="G3 box; other site" /db_xref="CDD:133300" misc_feature 29835..29846 /locus_tag="ClothDRAFT_1213" /note="G4 box; other site" /db_xref="CDD:133300" misc_feature 29934..29942 /locus_tag="ClothDRAFT_1213" /note="G5 box; other site" /db_xref="CDD:133300" misc_feature 30060..30308 /locus_tag="ClothDRAFT_1213" /note="TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867" /db_xref="CDD:133440" gene complement(30445..31023) /locus_tag="ClothDRAFT_1214" CDS complement(30445..31023) /locus_tag="ClothDRAFT_1214" /inference="protein motif:PFAM:PF01584" /note="PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: dds:Ddes_1022 CheW protein" /codon_start=1 /transl_table=11 /product="CheW protein" /protein_id="ZP_05429353.1" /db_xref="GI:256004372" /db_xref="InterPro:IPR002545" /translation="MEGMQIVVFSLNDEICGVDTSQVKEIVKYEEVSKMPRMPRFIDG VINLRGKVVPVVNLNKRFKLGDMEVGKKTKIIITDIEDKLIGFVVNDVYEIIRLSADD IEPTPEIIKKVYNDYLKCVGKKDDKLIAILDLSVILTDSEIDKLEENFEDENNTNDDN ENDDCNDNEGSSENNNEDKLEENTEENEKDKE" misc_feature complement(30598..31017) /locus_tag="ClothDRAFT_1214" /note="CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256" /db_xref="CDD:185867" gene 32018..33034 /locus_tag="ClothDRAFT_1215" CDS 32018..33034 /locus_tag="ClothDRAFT_1215" /EC_number="2.5.1.54" /inference="protein motif:TFAM:TIGR01361" /note="KEGG: gme:Gmet_0346 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA" /codon_start=1 /transl_table=11 /product="phospho-2-dehydro-3-deoxyheptonate aldolase" /protein_id="ZP_05429354.1" /db_xref="GI:256004373" /db_xref="InterPro:IPR006218" /db_xref="InterPro:IPR006268" /translation="MIIVMSPNATKEQIENVEKKLLELGFKTHPIVGDVKTVIGAIGD KRLLNTHSISTMPGVESIVPIMKPYKLASKELKQEPTIVEVGDVRIGGNEVVVMAGPC AIENEEIYVETAKKVKEAGAKILRGGAFKPRTSPYSFQGLEEEGLKIMAIAREVTGLK LVTEVVDTRDVELVASYTDIIQIGARNMQNFRLLKEVGMSNKPVLLKRGLAATIEEWL MAAEYIISEGNPNVILCERGIRTFETATRNTIDMSAIPVIKELSHLPIVLDPSHAAGT WKYVEPLAKGAIATGADGLIIEVHSQPDCALCDGQQSLIPSRFEQLMKDLEPIALAVG RKLL" misc_feature 32021..33025 /locus_tag="ClothDRAFT_1215" /note="3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673" /db_xref="CDD:181535" misc_feature 32225..33004 /locus_tag="ClothDRAFT_1215" /note="NeuB family; Region: NeuB; cl00496" /db_xref="CDD:186036" gene complement(33216..34346) /locus_tag="ClothDRAFT_1216" CDS complement(33216..34346) /locus_tag="ClothDRAFT_1216" /inference="protein motif:TFAM:TIGR00254" /note="KEGG: gme:Gmet_1298 diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein" /codon_start=1 /transl_table=11 /product="diguanylate cyclase" /protein_id="ZP_05429355.1" /db_xref="GI:256004374" /db_xref="InterPro:IPR000160" /translation="MNDIINGLLKKKKTGNFRQQRNFVYLRWVALLLVIPLFFLVSDC PRTEKSFWITFSVAILYNGFQTLLILFKRPNGWVKKFISIAFYFDIMFICAFSYILNG IESDIYILIFFVISYYGIGKDVSSTINISIFSIILYTVSSIAVKADNIGELNFLKLII RDFFILLVAYGVSMVILEVKKYDEMHQREFKLARTDKLTGLANRHMLDQKLEEEALYC EYSKKPLNVLMFDIDDFKKFNDTYGHIWGDKLLSLFGDIIKQSIRKTDMAFRYGGEEF MVLIRDLDLEKAKCVADRIRCQLEKQNLFSDEGHNMGKATVSCGIAQFPTHSDDIKKV VDYADRALYYAKKIGKNIVVSYDEIGKLTETVQINADTYLSK" misc_feature complement(33285..33767) /locus_tag="ClothDRAFT_1216" /note="Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949" /db_xref="CDD:143635" misc_feature complement(order(33525..33527,33654..33656)) /locus_tag="ClothDRAFT_1216" /note="metal-binding site" /db_xref="CDD:143635" misc_feature complement(order(33522..33533,33537..33539,33603..33605, 33615..33617,33627..33632,33639..33641)) /locus_tag="ClothDRAFT_1216" /note="active site" /db_xref="CDD:143635" misc_feature complement(order(33465..33467,33549..33551)) /locus_tag="ClothDRAFT_1216" /note="I-site; other site" /db_xref="CDD:143635" gene complement(34444..35334) /locus_tag="ClothDRAFT_1217" CDS complement(34444..35334) /locus_tag="ClothDRAFT_1217" /inference="protein motif:PFAM:PF00892" /note="PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: rpe:RPE_4153 protein of unknown function DUF6, transmembrane" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF6 transmembrane" /protein_id="ZP_05429356.1" /db_xref="GI:256004375" /db_xref="InterPro:IPR000620" /db_xref="InterPro:IPR004853" /translation="MRKFNFGYLFILVTVVFFSTYEVVSKTIIGKVDPFQINFLRFFI GGSLLFLFLLIKRDVKIDRKSLMIVSAAGILNVVFSMNLLQLSLNVAYAKAAVVAVIF SSNPIFVSIFAAVMDKEKITLFKAAGMFLGMLGIAVISINGQAFRDINILSPLLALMS AGLYGLYTVVGRRASSKIGSIKMNAYSFLIGSLILLSVLLIKGLPAFKFDCSAWPQVV YLSVFVTGIAYLIYFMGLVRTGAGSGSVVFFLKPVLASVFAIVFLGEKITLNLIFGTF LILLGMAVMFYWEKIRQRFV" misc_feature complement(34474..34848) /locus_tag="ClothDRAFT_1217" /note="EamA-like transporter family; Region: EamA; cl01037" /db_xref="CDD:154161" gene 35585..36004 /locus_tag="ClothDRAFT_1218" CDS 35585..36004 /locus_tag="ClothDRAFT_1218" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: zinc finger protein 557" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429357.1" /db_xref="GI:256004376" /translation="MIDVVTCEICGRLYNNPSGFFRVCPTCYENDENEFQKIKDYLNV HPCAKIFDVVADLNISIKQIKRYLRESRLEILEKDNHFLLCESCGKSIRTGRYCDECY KNRHKNIRAVYSGSSNIKHSNAIRFRTDGNSKRASSI" misc_feature 35603..35923 /locus_tag="ClothDRAFT_1218" /note="flagellar operon protein TIGR03826; Region: YvyF" /db_xref="CDD:163538" gene complement(36118..36684) /locus_tag="ClothDRAFT_1219" CDS complement(36118..36684) /locus_tag="ClothDRAFT_1219" /inference="protein motif:PFAM:PF01464" /note="PFAM: Lytic transglycosylase catalytic; KEGG: tcx:Tcr_0924 lytic transglycosylase, catalytic" /codon_start=1 /transl_table=11 /product="Lytic transglycosylase catalytic" /protein_id="ZP_05429358.1" /db_xref="GI:256004377" /db_xref="InterPro:IPR000189" /db_xref="InterPro:IPR008258" /translation="MFHRLKRSFKLFFVFAVALISIIFILEGTVKMLFPLKYKEYVYK YSSEYNLDPYLVFSIIKAESSFNPNATSHKNARGLMQLTDETALWIAEMMGLENFKVE YLYDPETNIKFGCWLLNNLEKQFDSRILVVASYNAGAACVHSWLKDSKYSKTGKTLDV IPYKETEIYTKRVENYYSIYKMLYEKDV" sig_peptide complement(36598..36684) /locus_tag="ClothDRAFT_1219" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.721) with cleavage site probability 0.435 at residue 29" misc_feature complement(36154..36528) /locus_tag="ClothDRAFT_1219" /note="Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic 'goose-type' lysozymes (GEWL). LTs catalyze...; Region: LT_GEWL; cd00254" /db_xref="CDD:29556" misc_feature complement(order(36280..36282,36334..36336,36436..36438, 36496..36498)) /locus_tag="ClothDRAFT_1219" /note="N-acetyl-D-glucosamine binding site; other site" /db_xref="CDD:29556" misc_feature complement(36496..36498) /locus_tag="ClothDRAFT_1219" /note="catalytic residue; other site" /db_xref="CDD:29556" gene complement(36722..36883) /locus_tag="ClothDRAFT_1220" CDS complement(36722..36883) /locus_tag="ClothDRAFT_1220" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: dephospho-CoA kinase" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429359.1" /db_xref="GI:256004378" /translation="MKRSGFSYEQVLERINAQLSDEYYCSLADVIIENGGTCEELRRI VEAHYNKRL" misc_feature complement(36764..>36883) /locus_tag="ClothDRAFT_1220" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" gene complement(36976..37308) /locus_tag="ClothDRAFT_1221" CDS complement(36976..37308) /locus_tag="ClothDRAFT_1221" /inference="protein motif:PFAM:PF01121" /note="PFAM: Dephospho-CoA kinase; KEGG: swp:swp_4764 dephospho-CoA kinase" /codon_start=1 /transl_table=11 /product="Dephospho-CoA kinase" /protein_id="ZP_05429360.1" /db_xref="GI:256004379" /db_xref="InterPro:IPR001977" /translation="MRTIGVTGGIGSGKSTVSKILADLGAQIIDADVIARDVILKGHE AYQEIVDYFGSQILLPDGEIDRKKLAGEVFNNKDKLEILNGITHKHVAQIIIERHEIL KKREKLLL" misc_feature complement(<36979..37299) /locus_tag="ClothDRAFT_1221" /note="Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022" /db_xref="CDD:30195" misc_feature complement(order(37045..37047,37213..37215,37288..37290)) /locus_tag="ClothDRAFT_1221" /note="CoA-binding site; other site" /db_xref="CDD:30195" misc_feature complement(order(37267..37272,37279..37287)) /locus_tag="ClothDRAFT_1221" /note="ATP-binding; other site" /db_xref="CDD:30195" gene complement(37384..40068) /locus_tag="ClothDRAFT_1222" CDS complement(37384..40068) /locus_tag="ClothDRAFT_1222" /EC_number="2.7.7.7" /inference="protein motif:TFAM:TIGR00593" /note="KEGG: dat:HRM2_12370 PolA; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; 3'-5' exonuclease; Helix-hairpin-helix domain protein class 2" /codon_start=1 /transl_table=11 /product="DNA polymerase I" /protein_id="ZP_05429361.1" /db_xref="GI:256004380" /db_xref="InterPro:IPR001098" /db_xref="InterPro:IPR002298" /db_xref="InterPro:IPR002421" /db_xref="InterPro:IPR002562" /db_xref="InterPro:IPR008918" /translation="MSKQKLMAIDGNSILNRAFYGLPELLTTSDGIYTNGIYVFLNIM HKFIEEENPEYICVAFDLKAPTFRHNKYEGYKANRKGMPEELRVQVPLLKEVLDAMNI KRLEMEGFEADDILGSVSLCAEKKGLEVILVTGDRDAFQLIGPSTRLKLPRTRGGKTE VEEYDYNKIVEVYGIKPEQFVDVKALAGDTSDNIPGVPGIGEKTALALIKEYNNLENL YNSLDSIKKKGLREKLETFKEQAFLSRELALIERNMPSLCDIEELKRVEIDREKTYEI FKRLEFRSFIDKFGLNDVQIQNTVELNVKIAKNASELESLKNNILKSRKVCIYHLIDK TGSFSQKLAAIAISPVEDEAWYLDFTNNIDEDEFFRQFKDVLEDGNIKKYGHDLKNFI VYLNNRGIDFNGLAFDTMIGAYIINPSKETYTISELAQEYLNLSVKAVEELAGKGKSF TLFKDMQPDVLSKTVGVYPHVISKVSRKIDSLLKENNQERLYYDIELPLVRTLADMEY YGFKVNVDALVEFSKELQEKIDVVTKEIYTLAGEEFNINSPKQLGVILFEKLGLPIIK KTKTGYSTDAEVLEELSDRHEIVEKILEYRQLVKLKSTYAEGLLAVINPYTGKIHSSF NQTVTATGRISSTEPNLQNIPIKLEMGRKIRKVFIPSDENYLLLDADYSQIELRVLAH ITNDENMINAFLNNEDIHTSTAASVFGIPKEEVTPLMRSRAKAVNFGIVYGIGDFSLA KDLKISRKEARAYIDGYLDRYPNVKKYMHDIVEEGKEKGFVTTMFMRRRYLPELKSRN FNIRSFGERVAMNTPIQGSAADIIKIAMVKVHGELKKRKLKSRLILQVHDELIVETFK DEKEEVEKILLEGMQNAVSLKVPLVVEIKSGSNWYETK" misc_feature complement(37387..40062) /locus_tag="ClothDRAFT_1222" /note="DNA polymerase I; Provisional; Region: PRK05755" /db_xref="CDD:180237" misc_feature complement(39319..40056) /locus_tag="ClothDRAFT_1222" /note="5'-3' exonuclease; T5 type 5'-3' exonuclease domains may co-occur with DNA polymerase I (Pol I) domains, or be part of Pol I containing complexes. They digest dsDNA and ssDNA, releasing mono-,di- and tri-nucleotides, as well as oligonucleotides, and...; Region: 53EXOc; cd00008" /db_xref="CDD:28892" misc_feature complement(order(39661..39663,39730..39732,39736..39738, 39886..39888,40039..40041)) /locus_tag="ClothDRAFT_1222" /note="metal binding site I; metal-binding site" /db_xref="CDD:28892" misc_feature complement(order(39820..39822,39829..39876)) /locus_tag="ClothDRAFT_1222" /note="putative ssDNA interaction site; other site" /db_xref="CDD:28892" misc_feature complement(order(39493..39495,39502..39504,39655..39657, 39661..39663)) /locus_tag="ClothDRAFT_1222" /note="metal binding site II; metal-binding site" /db_xref="CDD:28892" misc_feature complement(38554..39105) /locus_tag="ClothDRAFT_1222" /note="inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140" /db_xref="CDD:176652" misc_feature complement(37396..38529) /locus_tag="ClothDRAFT_1222" /note="Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637" /db_xref="CDD:176474" misc_feature complement(order(37525..37533,37624..37626,37645..37647, 37897..37899,37909..37911,37969..37971,38053..38058, 38155..38166,38170..38172,38176..38184,38257..38262, 38269..38271,38281..38283)) /locus_tag="ClothDRAFT_1222" /note="active site" /db_xref="CDD:176474" misc_feature complement(order(37525..37533,37624..37626,37636..37638, 37645..37650,37873..37875,38155..38166,38170..38172, 38176..38184,38257..38262,38269..38271,38281..38283)) /locus_tag="ClothDRAFT_1222" /note="DNA binding site" /db_xref="CDD:176474" misc_feature complement(order(37525..37527,37897..37899,37909..37911, 37969..37971,38047..38049,38053..38058)) /locus_tag="ClothDRAFT_1222" /note="catalytic site; other site" /db_xref="CDD:176474" gene complement(40169..40381) /locus_tag="ClothDRAFT_1223" CDS complement(40169..40381) /locus_tag="ClothDRAFT_1223" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429362.1" /db_xref="GI:256004381" /translation="MFIDAVVKRIENGYAVLVSDDCGVEVSIPVRECEGMYMKGENVS LIIDNGGSINSIADKETKKRNPTNEE" gene complement(40606..41307) /locus_tag="ClothDRAFT_1224" CDS complement(40606..41307) /locus_tag="ClothDRAFT_1224" /inference="protein motif:PFAM:PF07238" /note="PFAM: type IV pilus assembly PilZ" /codon_start=1 /transl_table=11 /product="type IV pilus assembly PilZ" /protein_id="ZP_05429363.1" /db_xref="GI:256004382" /db_xref="InterPro:IPR009875" /translation="MMNVELSNWIPVQREEYVLSVKEKEEIFRRGAVISIKHGYIFEP VLSVIQKCEGECIYFRIPEEFLKNNVFKGDVVSCQVMQGEYEYIVSGIISEFEITYPW LVEVAIKRVSKVKNNRGAKRYLVNFQSRFYPKGSDNGIYAIIKNISLTGVGAVFREEV QPHSLVNVFVSASVDKVQSLEFKAKINRIVNREIYNEYGLEIVEIDEVNKDKLDKLIY RLECNEAEFVSNSLK" misc_feature complement(40651..40962) /locus_tag="ClothDRAFT_1224" /note="PilZ domain; Region: PilZ; cl01260" /db_xref="CDD:163963" gene complement(41437..42426) /locus_tag="ClothDRAFT_1225" CDS complement(41437..42426) /locus_tag="ClothDRAFT_1225" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: sfu:Sfum_1326 hypothetical protein" /codon_start=1 /transl_table=11 /product="putative transmembrane anti-sigma factor" /protein_id="ZP_05429364.1" /db_xref="GI:256004383" /translation="MKNCGEIIELMSLYIDGELDSETKREFEEHIETCESCRSELYEL KEIVDVLGEVEEVELPSGFKEQLHEKLVAEKKKNESESKILSFRKKFIGFAPSIAAGL VLVFVAASLIITRGLFGNVPSTNTGGSMGIEYSGMMESDQKNNKDGQYNGLKNEEDSQ VSVLFNEEPGATQSQKFYDGAEDSLQKEKSEDARKIENSSFYEITSSSDVPASEQPQK TYSIAATGMTVYDVNITVNSPDLEKDTDNIINIARSCNVEIEVEIEKSGHKSVAFSGL DENKNTLNFSMDAATYENFISKLKEEYGSKLSLDEKTDDSEKTKRVEITIFKE" misc_feature complement(<42061..42426) /locus_tag="ClothDRAFT_1225" /note="Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662" /db_xref="CDD:35221" misc_feature complement(<42295..42426) /locus_tag="ClothDRAFT_1225" /note="Predicted integral membrane protein [Function unknown]; Region: COG5660" /db_xref="CDD:35219" gene complement(42447..43043) /locus_tag="ClothDRAFT_1226" CDS complement(42447..43043) /locus_tag="ClothDRAFT_1226" /inference="protein motif:TFAM:TIGR02937" /note="TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: asa:ASA_3492 RNA polymerase sigma factor RpoE" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma-24 subunit, ECF subfamily" /protein_id="ZP_05429365.1" /db_xref="GI:256004384" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR014284" /translation="MSSSEKELIKRAKKGDVEAFEQLIEGCQKKVFNIALRMLGNYDD ASELAQEVFLKAYKSIKNFKGDSLFNTWIYKVTTNACLDEIRKRKNKKVVYLDEDIEL GGNEIKRQIKDDSPGPELKAEDNELKRAVMDSINMLPEEYRTVIVLRDIQGFTYEEIA NIIKCPEGTVKSRINRARQALKKILQQKKELINEEYVK" misc_feature complement(42504..43019) /locus_tag="ClothDRAFT_1226" /note="RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652" /db_xref="CDD:182019" misc_feature complement(42777..42977) /locus_tag="ClothDRAFT_1226" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature complement(42507..42662) /locus_tag="ClothDRAFT_1226" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cd06171" /db_xref="CDD:100119" misc_feature complement(order(42510..42512,42516..42521,42525..42533, 42537..42542,42546..42548,42576..42581,42597..42599, 42627..42629)) /locus_tag="ClothDRAFT_1226" /note="DNA binding residues" /db_xref="CDD:100119" gene 43284..43727 /locus_tag="ClothDRAFT_1227" CDS 43284..43727 /locus_tag="ClothDRAFT_1227" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: tdn:Suden_1924 response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase" /codon_start=1 /transl_table=11 /product="response regulator receiver protein" /protein_id="ZP_05429366.1" /db_xref="GI:256004385" /db_xref="InterPro:IPR001789" /translation="MINTILVIDDNVFDNAIIKNYLSGERYSIISAVNGREALELIES RNIDLILLDIVMPIMDGYDFLKEFSKTPYYKEIPVIVASNLDNAENIEKIFEFEIFDY IIKPLDQINKLIFLNKIKSALKYRNALSELNKATRLINQLSAKEA" misc_feature 43299..43652 /locus_tag="ClothDRAFT_1227" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(43308..43313,43440..43442,43464..43466,43530..43532, 43587..43589,43596..43601) /locus_tag="ClothDRAFT_1227" /note="active site" /db_xref="CDD:29071" misc_feature 43440..43442 /locus_tag="ClothDRAFT_1227" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature order(43449..43454,43458..43466) /locus_tag="ClothDRAFT_1227" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature 43596..43604 /locus_tag="ClothDRAFT_1227" /note="dimerization interface; other site" /db_xref="CDD:29071" gene complement(44233..45339) /locus_tag="ClothDRAFT_1228" CDS complement(44233..45339) /locus_tag="ClothDRAFT_1228" /inference="protein motif:PFAM:PF01784" /note="PFAM: protein of unknown function DUF34; KEGG: gme:Gmet_0399 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF34" /protein_id="ZP_05429367.1" /db_xref="GI:256004386" /db_xref="InterPro:IPR002678" /translation="MSIKAKDIIKYMEELAPVSLAEDYDNVGLLIGSRESTVERIFVC LDVTSKTVDEAVAKKADLIVSHHPVIFKGLKRINEDDPKGNIIYKLIRNNIGVYSAHT NLDVAHGGVNNYLSSILGLKDIISLKDYKAEKLYKVVVFVPHESVDAVRDAMSRAGAG WIGNYSDCSFMTAGTGTFRPLEGTNPYIGTTGNLEKVDEYRIETVVSQRNLKKVIEAM IKVHPYEEVAYDVYPLEIKGRQYGMGNVGVLDKPKSLDEFIAVVKEKLGVKNVRVIGE TNKEIEKVAVFCGSFDRDVMEAAKSKADVLVTGDVKYHDAVDMLEIGMCVIDAGHFNT ERIIADRLAQLIKENFPEVEVIKSNMEEDPFKFY" misc_feature complement(<44929..45321) /locus_tag="ClothDRAFT_1228" /note="NIF3 (NGG1p interacting factor 3); Region: NIF3; cl01309" /db_xref="CDD:186417" misc_feature complement(44635..44946) /locus_tag="ClothDRAFT_1228" /note="Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323" /db_xref="CDD:33132" misc_feature complement(44293..>44652) /locus_tag="ClothDRAFT_1228" /note="NIF3 (NGG1p interacting factor 3); Region: NIF3; cl01309" /db_xref="CDD:186417" gene complement(45353..46057) /locus_tag="ClothDRAFT_1229" CDS complement(45353..46057) /locus_tag="ClothDRAFT_1229" /inference="protein motif:PFAM:PF04816" /note="PFAM: protein of unknown function DUF633; KEGG: ppw:PputW619_2868 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF633" /protein_id="ZP_05429368.1" /db_xref="GI:256004387" /db_xref="InterPro:IPR006901" /translation="MELKGRLKLIADLTPKCNIVCDIGTDHAYIPIYLVMNKKCQRAL ACDVRKGPIGFAEKNIAEYGLSQYISTRIGYGLEPLEDNEVDVVVIAGMGGLLIKEIL EKGFGKAKRANALIIQPMNAIELVRRWLCENGFDIFDERLAKEEEDRIYTAMAVKWTG EVKIKDEVYYYIGEKLFENKDPLLPELIKKKIGQMDKIILEMEKMNDKNSKKRLDTIR IRNEISRLFTEYQEKA" misc_feature complement(45383..46057) /locus_tag="ClothDRAFT_1229" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene 46174..46344 /locus_tag="ClothDRAFT_1230" CDS 46174..46344 /locus_tag="ClothDRAFT_1230" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429369.1" /db_xref="GI:256004388" /translation="MIQSHRLVAKDTEKPFETEITGITEPLYQVISKKSTPALSHREL NENFDTFLETKK" gene complement(46383..46459) /locus_tag="ClothDRAFT_R0028" /note="tRNA-Met1" tRNA complement(46383..46459) /locus_tag="ClothDRAFT_R0028" /product="tRNA-Met" gene complement(46463..46538) /locus_tag="ClothDRAFT_R0027" /note="tRNA-Asn1" tRNA complement(46463..46538) /locus_tag="ClothDRAFT_R0027" /product="tRNA-Asn" gene complement(46692..46910) /locus_tag="ClothDRAFT_1231" CDS complement(46692..46910) /locus_tag="ClothDRAFT_1231" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429370.1" /db_xref="GI:256004389" /translation="MEDMNRNEIEITTYDRLLRAWENSMELVRDYEMYSKRIEDQKIK EIFKRYAEDEGRHAAELRELLLEYKNKN" gene complement(47197..48273) /locus_tag="ClothDRAFT_1232" CDS complement(47197..48273) /locus_tag="ClothDRAFT_1232" /inference="protein motif:TFAM:TIGR02393" /note="TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; Bacterio-opsin activator HTH domain protein; sigma-70 1.1 domain protein; sigma-70 region 4 domain protein; KEGG: gme:Gmet_0395 RNA polymerase sigma factor RpoD-like" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma 70 subunit, RpoD subfamily" /protein_id="ZP_05429371.1" /db_xref="GI:256004390" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007050" /db_xref="InterPro:IPR007127" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR009042" /db_xref="InterPro:IPR012760" /db_xref="InterPro:IPR014284" /translation="MKPNSDKKAILLELIEKGKQKGMLTYQEIMDAFEEVDIDPEQIE KIYETLENMGIDVVGDIEAEMEDIQLTEDDLDLSIPEGISIDDPVRMYLKEIGKVPLL TAEEEIELAHRMEQGDAEAKRRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNLGLIK AVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRVSRQLLQ ELGREPHPEEIAKEMNMPVEKVREIMKISQEPVSLETPIGEEEDSHLGDFIPDDDAPA PSEAAAFTLLKEQLVDVLDTLTPREEKVLRLRFGLDDGRARTLEEVGKEFNVTRERIR QIEAKALRKLRHPSRSKKLKDYLD" misc_feature complement(47200..48273) /locus_tag="ClothDRAFT_1232" /note="RNA polymerase sigma factor RpoD; Validated; Region: PRK09210" /db_xref="CDD:181701" misc_feature complement(48028..48237) /locus_tag="ClothDRAFT_1232" /note="Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979" /db_xref="CDD:112778" misc_feature complement(47908..48018) /locus_tag="ClothDRAFT_1232" /note="Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140" /db_xref="CDD:143911" misc_feature complement(47689..47901) /locus_tag="ClothDRAFT_1232" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature complement(47467..47664) /locus_tag="ClothDRAFT_1232" /note="Sigma-70 region 3; Region: Sigma70_r3; pfam04539" /db_xref="CDD:146934" misc_feature complement(47239..47415) /locus_tag="ClothDRAFT_1232" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cd06171" /db_xref="CDD:100119" misc_feature complement(order(47251..47253,47257..47262,47266..47274, 47278..47283,47287..47289,47317..47322,47350..47352, 47380..47382)) /locus_tag="ClothDRAFT_1232" /note="DNA binding residues" /db_xref="CDD:100119" gene complement(48323..49702) /locus_tag="ClothDRAFT_1233" CDS complement(48323..49702) /locus_tag="ClothDRAFT_1233" /inference="protein motif:PFAM:PF08275" /note="PFAM: DNA primase catalytic core domain; TOPRIM domain protein; SMART: Toprim sub domain protein; KEGG: gme:Gmet_0394 DNA primase" /codon_start=1 /transl_table=11 /product="DNA primase catalytic core domain protein" /protein_id="ZP_05429372.1" /db_xref="GI:256004391" /db_xref="InterPro:IPR006154" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR013264" /translation="MTKRKVSGSIARKFGLGYSPEEWDALYNHLRKKGYDDEILLDSG LILKGKNGGYYDRFRGRIIFPIFDLRGNVIGFGGRVLDNSTPKYMNSPETLVYNKRKN LYGLNFAKNSGQKRIIVVEGYMDVISLFQFGIINTVASLGTALTESQGRILKKYAEEI IISYDADTAGMAATMRGLDLLNDIGCNVKVLIIPEGKDPDEFVKKNGPEAFNKLVENA LSLVEYKIKALKSTIDTNTTEGKINFLNKAADLLSKIDNNMEREMYIKKISKEYDISQ ESIYAEILKRIKPKTVYKPLTRTLTAKNDNNRLKIEKNGKKSSYDKIIECERMLLCLL SIDNSLYKVVKDKIIVDEFKDEQNKEIAKIVFKRFEEKKGIVPAELINLAGEETSGVF ARLIQGECNFDDNIKAVMDIIKKMELYRLEDRQKEILQQLSSGNLSTEDSEKLKLELK EVLLKMKSI" misc_feature complement(49373..49699) /locus_tag="ClothDRAFT_1233" /note="DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275" /db_xref="CDD:149368" misc_feature complement(49130..49360) /locus_tag="ClothDRAFT_1233" /note="TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364" /db_xref="CDD:173784" misc_feature complement(order(49196..49198,49202..49204,49208..49210, 49328..49330,49337..49342)) /locus_tag="ClothDRAFT_1233" /note="active site" /db_xref="CDD:173784" misc_feature complement(order(49208..49210,49340..49342)) /locus_tag="ClothDRAFT_1233" /note="metal-binding site" /db_xref="CDD:173784" misc_feature complement(order(49280..49282,49310..49315,49331..49336)) /locus_tag="ClothDRAFT_1233" /note="interdomain interaction site; other site" /db_xref="CDD:173784" misc_feature complement(48866..49042) /locus_tag="ClothDRAFT_1233" /note="DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410" /db_xref="CDD:150991" gene complement(49735..50124) /locus_tag="ClothDRAFT_1234" CDS complement(49735..50124) /locus_tag="ClothDRAFT_1234" /inference="protein motif:PFAM:PF01807" /note="PFAM: zinc finger CHC2-family protein; SMART: zinc finger CHC2-family protein; KEGG: dol:Dole_2153 DNA primase" /codon_start=1 /transl_table=11 /product="zinc finger CHC2-family protein" /protein_id="ZP_05429373.1" /db_xref="GI:256004392" /db_xref="InterPro:IPR002694" /translation="MYKYYPEELIEEIRMSNDILSVVGEYVKLERKGKNYFGLCPFHS EKTPSFSVDPNKQLYYCFGCGKGGSVIQFVMEVENLDYIEAVKMLAERARIQLPEGDN EKKGLLPEKSRNFLELMLKRPVFSMSS" misc_feature complement(49831..50112) /locus_tag="ClothDRAFT_1234" /note="CHC2 zinc finger; Region: zf-CHC2; cl02597" /db_xref="CDD:141551" gene complement(50483..51478) /locus_tag="ClothDRAFT_1235" CDS complement(50483..51478) /locus_tag="ClothDRAFT_1235" /inference="protein motif:TFAM:TIGR01353" /note="KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region" /codon_start=1 /transl_table=11 /product="deoxyguanosinetriphosphate triphosphohydrolase" /protein_id="ZP_05429374.1" /db_xref="GI:256004393" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006261" /db_xref="InterPro:IPR006674" /translation="MLIREELEKLEAQILSPYAAKSADSRGRLREEKECDIRTRFQRD RDRILYSKAFRRLKHKTQVFLSPEGDHYRTRLTHTLEVSQIARTIAKSLRLNEDLTEA IALGHDLGHTPFGHAGERVLNEICPHGFKHNEQSLRVVDVLEKDNGLNLTWEVRDGIL NHTGNTIPSTLEGQIIRYADRIAYINHDIDDAIRGGIISEDSLPKECVKVLGNTSGRR INNMIVDIIANSKDRNTIKMSSEFQEAMDELREFMFDNVYIGSKAKKHEMKAQNIIKE LYNYLKKRPEFLSEEAAKMLQHSDIDRVVCDYIAGMTDRYAVKKFHEIFIPESWH" misc_feature complement(50504..51403) /locus_tag="ClothDRAFT_1235" /note="deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096" /db_xref="CDD:179219" misc_feature complement(50915..51262) /locus_tag="ClothDRAFT_1235" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077" /db_xref="CDD:28958" misc_feature complement(order(50939..50941,51155..51160,51245..51247)) /locus_tag="ClothDRAFT_1235" /note="Zn2+ binding site; other site" /db_xref="CDD:28958" misc_feature complement(51155..51157) /locus_tag="ClothDRAFT_1235" /note="Mg2+ binding site; other site" /db_xref="CDD:28958" misc_feature complement(50504..>50944) /locus_tag="ClothDRAFT_1235" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076" /db_xref="CDD:185790" gene complement(51625..52662) /locus_tag="ClothDRAFT_1236" CDS complement(51625..52662) /locus_tag="ClothDRAFT_1236" /inference="protein motif:TFAM:TIGR00277" /note="KEGG: sde:Sde_0670 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region" /codon_start=1 /transl_table=11 /product="metal dependent phosphohydrolase" /protein_id="ZP_05429375.1" /db_xref="GI:256004394" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /translation="MSKIFLPLEEVKPGMRIAETIMNDYGSVVISEGTILDDHMIKKL VNLNYTKVRVIEKDKNFVSSEISESFNVSYNASVNCFKSILYDAAVGKNINMEKVDKV VMSVVARLDEKRDIVRCINQIKSADQYTYTHCVNVSLLCMLLGKWLGYSKDSLIKLVQ AGLLHDIGKAKVPKEILNKPSKLTPEEYEEIKKHTVYGYRILEKEHEIDRDVAIAVLM HHERMDGSGYPTGAKSDQINMMARVIAVADIYDAMTSNRVYREKESPFEVFHIIEEEA VGKLDVRVVNAFLSNIAAYYIGDFAKLNTGEICEIVYINPRYVSRPIIRVDDQYIDLT VEKDLKILEIL" misc_feature complement(51874..52281) /locus_tag="ClothDRAFT_1236" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077" /db_xref="CDD:28958" misc_feature complement(order(51919..51921,52165..52170,52264..52266)) /locus_tag="ClothDRAFT_1236" /note="Zn2+ binding site; other site" /db_xref="CDD:28958" misc_feature complement(52165..52167) /locus_tag="ClothDRAFT_1236" /note="Mg2+ binding site; other site" /db_xref="CDD:28958" gene 53039..53311 /locus_tag="ClothDRAFT_1237" CDS 53039..53311 /locus_tag="ClothDRAFT_1237" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429376.1" /db_xref="GI:256004395" /translation="MQLNNMKKIERIAKQFNKINRLSKIIIKYGFFTFFALFLLGALT ILMYQTVFYSNSYIYYLGTQIVKTSFTILAEVIIGGLVIDFIAEKG" sig_peptide 53039..53209 /locus_tag="ClothDRAFT_1237" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.933) with cleavage site probability 0.798 at residue 57" gene complement(53352..53732) /locus_tag="ClothDRAFT_1238" CDS complement(53352..53732) /locus_tag="ClothDRAFT_1238" /EC_number="4.1.1.11" /inference="protein motif:TFAM:TIGR00223" /note="KEGG: cju:C8J_0273 aspartate alpha-decarboxylase; TIGRFAM: aspartate 1-decarboxylase; PFAM: aspartate decarboxylase" /codon_start=1 /transl_table=11 /product="aspartate 1-decarboxylase" /protein_id="ZP_05429377.1" /db_xref="GI:256004396" /db_xref="InterPro:IPR003190" /translation="MFITLMKSKIHRATVTEANLDYVGSITIDEDLMEAADIMENEKV QVVDNNNGNRFETYVIKGERGSGMICLNGAAARLVHPGDLIIIISYGIFDREEAKTFN PKVVFVDEKNKIINIKSEEKHGEI" misc_feature complement(53406..53726) /locus_tag="ClothDRAFT_1238" /note="Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919" /db_xref="CDD:132994" misc_feature complement(order(53430..53432,53457..53465,53475..53477, 53499..53504,53508..53513,53559..53573,53577..53579, 53586..53588,53592..53594,53604..53609,53616..53618, 53622..53624,53664..53675,53697..53702,53706..53708, 53712..53726)) /locus_tag="ClothDRAFT_1238" /note="tetramerization interface; other site" /db_xref="CDD:132994" misc_feature complement(order(53559..53561,53658..53663,53700..53702, 53706..53708)) /locus_tag="ClothDRAFT_1238" /note="active site" /db_xref="CDD:132994" gene complement(53738..54583) /locus_tag="ClothDRAFT_1239" CDS complement(53738..54583) /locus_tag="ClothDRAFT_1239" /EC_number="6.3.2.1" /inference="protein motif:TFAM:TIGR00018" /note="KEGG: gme:Gmet_1643 pantothenate synthetase; TIGRFAM: pantoate/beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase" /codon_start=1 /transl_table=11 /product="pantoate/beta-alanine ligase" /protein_id="ZP_05429378.1" /db_xref="GI:256004397" /db_xref="InterPro:IPR003721" /translation="MRVIETISDLKAIIRTQKNLGRVIGLVPTMGYLHEGHLSLVNMS RQNNDYTVMSIFVNPTQFGPNEDFDRYPRDLERDLKLAEAAGVDVVFAPSVKEMYPDG YKTYVNVEGITEVLCGKSRPGHFRGVTTIVTKLFNIVEPHRAYFGQKDAQQVAVIKKM VKDLNMNVEIITCPIVREEDGLAMSSRNVYLSPEERKSAVILSKSLMEAEELIKKGET DAKKIRKYIIDRIQTEKNAVIDYVEVVNADTLENVDEIKGRVLVALAVKFGSTRLIDN VIVEV" misc_feature complement(53747..54583) /locus_tag="ClothDRAFT_1239" /note="pantoate--beta-alanine ligase; Region: panC; TIGR00018" /db_xref="CDD:161666" misc_feature complement(53753..54583) /locus_tag="ClothDRAFT_1239" /note="Pantoate-beta-alanine ligase; Region: PanC; cd00560" /db_xref="CDD:185673" misc_feature complement(order(54023..54034,54056..54064,54125..54127, 54134..54139,54143..54148,54188..54193,54200..54202, 54371..54373,54401..54403,54410..54412,54464..54466, 54473..54478,54482..54484,54491..54502)) /locus_tag="ClothDRAFT_1239" /note="active site" /db_xref="CDD:185673" misc_feature complement(order(54032..54037,54056..54061,54125..54127, 54134..54139,54143..54148,54188..54193,54401..54403, 54464..54466,54473..54475,54482..54484,54494..54502)) /locus_tag="ClothDRAFT_1239" /note="ATP-binding site; other site" /db_xref="CDD:185673" misc_feature complement(order(54125..54127,54179..54181,54188..54193, 54401..54403,54410..54412,54494..54496,54500..54502)) /locus_tag="ClothDRAFT_1239" /note="pantoate-binding site; other site" /db_xref="CDD:185673" misc_feature complement(54473..54484) /locus_tag="ClothDRAFT_1239" /note="HXXH motif; other site" /db_xref="CDD:185673" gene complement(54644..55495) /locus_tag="ClothDRAFT_1240" CDS complement(54644..55495) /locus_tag="ClothDRAFT_1240" /EC_number="2.1.2.11" /inference="protein motif:TFAM:TIGR00222" /note="KEGG: sat:SYN_02773 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase" /codon_start=1 /transl_table=11 /product="3-methyl-2-oxobutanoate hydroxymethyltransferase" /protein_id="ZP_05429379.1" /db_xref="GI:256004398" /db_xref="InterPro:IPR003700" /translation="MNDKFTTASFLESKKQGRKITMLTAYDYPTAKILDEAGVDSILV GDSLGMVVLGYEDTTRVTMDDMVHHTKAVVRGVKRAMVVADMPFLSYHTGKNDSVRNA GRLVSEGGCKAVKLEGGEDIIENVKAIISAGIPVVGHLGYTPQSINVFGGHKAQGKTI DTAKKIYRDALLLQKAGVFAVVLECVPYKLAAFISKRLDIPTIGIGSGPDCDGQVLVI HDLTGMFKDFTPKHVKKYAEIGETVSTAVKSYIDEVKNGVFPTEKNSFKVDDWIIDEL DKVRFDI" misc_feature complement(54716..55477) /locus_tag="ClothDRAFT_1240" /note="Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557" /db_xref="CDD:119342" misc_feature complement(order(54764..54778,54785..54787,54827..54832, 54839..54841,54959..54961,55043..55054,55058..55063, 55091..55108,55160..55162,55175..55180,55187..55189, 55199..55201,55229..55234,55271..55273,55280..55282, 55289..55294,55301..55303,55316..55321,55331..55348, 55352..55354,55397..55399,55406..55417,55472..55477)) /locus_tag="ClothDRAFT_1240" /note="oligomerization interface; other site" /db_xref="CDD:119342" misc_feature complement(order(54845..54847,54851..54853,54944..54946, 55064..55066,55079..55081,55151..55153,55241..55243, 55355..55363,55367..55369,55424..55426)) /locus_tag="ClothDRAFT_1240" /note="active site" /db_xref="CDD:119342" misc_feature complement(order(55151..55153,55241..55243,55358..55360)) /locus_tag="ClothDRAFT_1240" /note="metal-binding site" /db_xref="CDD:119342" gene complement(55870..56826) /locus_tag="ClothDRAFT_1241" CDS complement(55870..56826) /locus_tag="ClothDRAFT_1241" /inference="protein motif:TFAM:TIGR00966" /note="TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: nis:NIS_1465 preprotein translocase subunit SecF" /codon_start=1 /transl_table=11 /product="protein-export membrane protein SecF" /protein_id="ZP_05429380.1" /db_xref="GI:256004399" /db_xref="InterPro:IPR003335" /db_xref="InterPro:IPR005665" /translation="MFNFDYVGKRKYFFILSTVLLLIGLVALIVRGGLNLDIQFRGGT QIEIEMENGDFDVIKAENIAKEAIGKSGIHVQKSYTFNPTNSDEAISFLVIKSSGKLT DDERNKVLDALKAEFNVKENGEMRVRDVDPSIGAELLTKGLLAVALSLILLILYIGIR FNIMSGLLAGFTAVVAVLHDVLMMVAVYAVFNIPVNESFIAAVLTILGYSVNDTIVIY DRIRENSRISRKDSIRTIVNNSITQSMSRTINTSVTTLISVITVYAFAAYNGIGSMKE FTFPLIIGLICGTYSSIFIASPLWELLKEKQAKRKASQAAKA" misc_feature complement(55918..56826) /locus_tag="ClothDRAFT_1241" /note="preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022" /db_xref="CDD:183847" misc_feature complement(55918..56505) /locus_tag="ClothDRAFT_1241" /note="Protein export membrane protein; Region: SecD_SecF; cl14618" /db_xref="CDD:176628" gene complement(56819..58156) /locus_tag="ClothDRAFT_1242" CDS complement(56819..58156) /locus_tag="ClothDRAFT_1242" /inference="protein motif:TFAM:TIGR01129" /note="TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: bja:bll4735 preprotein translocase subunit SecD" /codon_start=1 /transl_table=11 /product="protein-export membrane protein SecD" /protein_id="ZP_05429381.1" /db_xref="GI:256004400" /db_xref="InterPro:IPR001036" /db_xref="InterPro:IPR003335" /db_xref="InterPro:IPR005791" /translation="MRWSSGIKFFLVLAVIAAMTAIVFTGLKIPNTDFVIPKAYDGIR YGIDISGGVSAVLTAPDGITPTDDELDTVKGIIDTRLEGKQIYDKTVTVDRVNKRVLV EIPYKKGGEYGDPYETIADIGATAMLTFREVDEDKVDPETGVYEMTDRIVLQGNDIES AVAETDPQTQYGIVRLIFSDEGAKKFEEATERLVGKRIAIYLDDQMISAPIVNEKISG KDRAVINLGFIDRNESIEYAKELAAIIRSGALPFKLEAKDVNHISPIIGESALNISIY AGAVAIILVWLFMLLYYRVPGLVADITLLGQVAAIILVFVLSGMSLTLPGIAGLILTV GMSVDANVIIFERIKEELRSGKTVQAAIELGFKRAFTAILDGNLTTLITAAVLYYFGT GAVRSFAITLGLGIIVNFITAIVATKIVLNALSQIRVLRKPWLFGAKGGTANV" sig_peptide complement(58079..58156) /locus_tag="ClothDRAFT_1242" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.778 at residue 26" misc_feature complement(56849..>57988) /locus_tag="ClothDRAFT_1242" /note="preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812" /db_xref="CDD:180271" misc_feature complement(56915..57382) /locus_tag="ClothDRAFT_1242" /note="Protein export membrane protein; Region: SecD_SecF; cl14618" /db_xref="CDD:176628" gene complement(58319..58984) /locus_tag="ClothDRAFT_1243" CDS complement(58319..58984) /locus_tag="ClothDRAFT_1243" /inference="protein motif:TFAM:TIGR00277" /note="TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: dat:HRM2_02570 hypothetical protein" /codon_start=1 /transl_table=11 /product="metal dependent phosphohydrolase" /protein_id="ZP_05429382.1" /db_xref="GI:256004401" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /translation="MGLISLEDLKNNEEIRALFEVADRQLAALGYTEHSFRHVGLVAK EAGEILKTLGFPEREVELAKIAGYLHDIGNAVNRVDHAHSGAILAYNILTKMGMSYSE AAEIMLAIGNHDENTGAPVSNISAALILADKSDVHRTRVRNNDMATFDIHDRVNYAVE SSELYVDKEKKLVVLELQIDTKICPVMDYFEIFLVRMTMNRRAAEYLGLKFKLIINGT HLL" misc_feature complement(58463..58969) /locus_tag="ClothDRAFT_1243" /note="HD supefamily hydrolase [General function prediction only]; Region: COG3294" /db_xref="CDD:33103" misc_feature complement(<58646..58888) /locus_tag="ClothDRAFT_1243" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076" /db_xref="CDD:185790" gene complement(59015..60367) /locus_tag="ClothDRAFT_1244" CDS complement(59015..60367) /locus_tag="ClothDRAFT_1244" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; KEGG: eba:ebA2233 quinohemoprotein amine dehydrogenase, putative SAM-radical dependentactivating subunit" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05429383.1" /db_xref="GI:256004402" /db_xref="InterPro:IPR000385" /db_xref="InterPro:IPR007197" /translation="MAMIHKFSMMGTNIVVDVNSGAVHVVDDISFDILDYYKNFTAGE IKNKLAHKYNADEIDEALREIESLEAEGLLFSEDPYKEYVSSMDRKSVVKALCLHISH DCNLRCKYCFASTGNFGGQRNMMSLEVGKKAIDFLISESGNRKNLEIDFFGGEPMMNF DVVKGIIEYARQKEKEHNKNFRFTLTTNGLLLNDENIKYINENMQNIVLSIDGRKEVN DRMRIRIDGSGCYDDILPKFKYVAESRNQDNYYVRGTFTRENMDFSNDVLHLADEGFR QISVEPVVAAKDSGYDLREEDLPRLFEEYEKLAYEYVKRRKEGNWFNFFHFMIDLTQG PCIVKRLTGCGSGHEYLAVTPEGDIYPCHQFVGNEKFKMGNVKEGVLNRDIQNYFKNS NVYTKKECDSCWAKFYCSGGCAANSYNFHKDINTVYKVGCELEKKRVECALWIKAQEM " misc_feature complement(<59681..60076) /locus_tag="ClothDRAFT_1244" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature complement(59018..60058) /locus_tag="ClothDRAFT_1244" /note="Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641" /db_xref="CDD:30986" misc_feature complement(order(59738..59740,59804..59812,59903..59908, 59912..59914,60032..60040,60044..60046,60050..60052, 60056..60058)) /locus_tag="ClothDRAFT_1244" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene complement(60756..61667) /locus_tag="ClothDRAFT_1245" CDS complement(60756..61667) /locus_tag="ClothDRAFT_1245" /inference="protein motif:TFAM:TIGR00005" /note="KEGG: gur:Gura_0881 RluA family pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein" /codon_start=1 /transl_table=11 /product="pseudouridine synthase, RluA family" /protein_id="ZP_05429384.1" /db_xref="GI:256004403" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR006224" /db_xref="InterPro:IPR006225" /translation="MEEIILVSNESGIRIDAWLCGKVKDYSRSYIQKLINDGMILVNG KPVKSNYKIKQNDEILARIPEPQVLDVVAEDIDVPILYEDEHIIVVDKPKGMVVHPAA GNYSGTLVNALLKHCGTNLSNINGIIRPGIVHRIDKDTSGVLVVAKSNAAHEGLSEKL KDHDIERVYIAVVHGIIREDYGKIDAPIGRHPVDRKKMAVNTKNGRRAVTRFKVLERF KDATYIEATLETGRTHQIRVHMSYIGFPIIGDTVYGRKNDIYNINGQALHAKKLGFVH PIKGEYMEFESPLPEYFKELLEKLRKS" misc_feature complement(60765..61643) /locus_tag="ClothDRAFT_1245" /note="pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005" /db_xref="CDD:161659" misc_feature complement(61398..61631) /locus_tag="ClothDRAFT_1245" /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165" /db_xref="CDD:29105" misc_feature complement(order(61506..61508,61512..61526,61527..61532, 61551..61553,61557..61562,61569..61574,61578..61583, 61587..61592,61626..61628)) /locus_tag="ClothDRAFT_1245" /note="RNA binding surface; other site" /db_xref="CDD:29105" misc_feature complement(60846..61409) /locus_tag="ClothDRAFT_1245" /note="PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF...; Region: PseudoU_synth_RluCD_like; cd02869" /db_xref="CDD:30029" misc_feature complement(order(60957..60959,61257..61268)) /locus_tag="ClothDRAFT_1245" /note="active site" /db_xref="CDD:30029" gene complement(61793..62248) /locus_tag="ClothDRAFT_1246" CDS complement(61793..62248) /locus_tag="ClothDRAFT_1246" /inference="protein motif:TFAM:TIGR00077" /note="TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: geo:Geob_0391 lipoprotein signal peptidase" /codon_start=1 /transl_table=11 /product="lipoprotein signal peptidase" /protein_id="ZP_05429385.1" /db_xref="GI:256004404" /db_xref="InterPro:IPR001872" /translation="MIFIVLIAAFVAADQLTKYIVVRNIEFGDKISVIDNFFYLTHWR NTGAAWGIMQNGRYILVPVTVVLSILIVYFIFKNSNKFYRFSLSMILGGALGNLIDRV FRTDGVVDFLDFQFGNYHFPVFNVADTFVVVGTLLLAYYTLFIYKEDKK" misc_feature complement(61811..62209) /locus_tag="ClothDRAFT_1246" /note="Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458" /db_xref="CDD:186009" gene complement(62329..63996) /locus_tag="ClothDRAFT_1247" CDS complement(62329..63996) /locus_tag="ClothDRAFT_1247" /inference="protein motif:PFAM:PF00496" /note="PFAM: extracellular solute-binding protein family 5; KEGG: sat:SYN_00608 oligopeptide-binding protein" /codon_start=1 /transl_table=11 /product="extracellular solute-binding protein family 5" /protein_id="ZP_05429386.1" /db_xref="GI:256004405" /db_xref="InterPro:IPR000914" /translation="MRKRALLVVVLVIASIVFSACSIDLSRLLEEGNNDYDFLNNGMD DVLDTGPVKNGVLNLFSTEPDTLNPILTSNAYVKEYSCFVFESLVRLDGNQKAVPLLA ESWEGSDDGLVWTFYLKENIYWHDGIPFSAEDVEFTASVIMNAGVNSPYKTCFENVES FLAQDSRTFKVLLKSPNSFTPELMTFPVIPKHYFLGEDILTTPKNNSPIGTGPYKFAE YRQGEYIRLTCNENWWNKDDGIENGIDLPYIQEVNIKIYGKNQSVMNAFHSQQVDVIT LDRTNWTGYSGRSDIILKKYVSNEFEFVAFNLSNKILKEREVRTAIAYAVDREQIISS ILPGEAVASDLPVIPDTWLNDTNVVSYERDVEKAKQILSDAGWKESNGIFYKRINGVN TPLSLELMVNDDNEVRLSVAEMIKEQLKEAGIEIEIKKVKWEDELNGVQSGKFDMALI GCTVASIPDISFLYSSAQIGTGLNISGYSNEEVDRYLTLILKEKDPSMKKAYFINMKE IINRDVPCLGLYFYNNMVIYNKRLRGEFNPSIWGKYYDFTRWYIPVE" sig_peptide complement(63928..63996) /locus_tag="ClothDRAFT_1247" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.732 at residue 23" misc_feature complement(62395..63822) /locus_tag="ClothDRAFT_1247" /note="The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513" /db_xref="CDD:173878" misc_feature complement(62341..63816) /locus_tag="ClothDRAFT_1247" /note="ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747" /db_xref="CDD:31090" misc_feature complement(order(62617..62619,62641..62649,62683..62685, 62773..62775,63754..63756)) /locus_tag="ClothDRAFT_1247" /note="peptide binding site; other site" /db_xref="CDD:173878" misc_feature complement(order(62746..62748,62755..62760,62767..62769, 62995..63000,63190..63192,63202..63204,63214..63216)) /locus_tag="ClothDRAFT_1247" /note="dimer interface; other site" /db_xref="CDD:173878" gene complement(64112..64951) /locus_tag="ClothDRAFT_1248" CDS complement(64112..64951) /locus_tag="ClothDRAFT_1248" /inference="protein motif:PFAM:PF02578" /note="PFAM: protein of unknown function DUF152; KEGG: sat:SYN_01799 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF152" /protein_id="ZP_05429387.1" /db_xref="GI:256004406" /db_xref="InterPro:IPR003730" /translation="MDNRFASNKNITYKTKNQVEFIQFNNLLKYENIITHCFTTRRGG VSKGWYDSLNMAFNKTDDRRNVEENYRRVADALNLDIESMVFSNQVHQNRIRVVTEED RGKGITRESDIIGYDGLVTNSKEVTLVTFYADCVPVFLFDPEKTVISIAHSGWRGTVM KIAKEAVEKMKDVFSSKPENIVAAIGPSIGKCCFEVGDDVYDEFRAKIDWGTEYCHRT GQKWHFDLPAIIKRTLLEEGVEEENIVLSGICTKCNKDIFFSHRGDNGRTGTMVGIMK ING" misc_feature complement(64127..64876) /locus_tag="ClothDRAFT_1248" /note="Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496" /db_xref="CDD:31685" misc_feature complement(64127..64840) /locus_tag="ClothDRAFT_1248" /note="Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650" /db_xref="CDD:186127" gene complement(65259..68492) /locus_tag="ClothDRAFT_1249" CDS complement(65259..68492) /locus_tag="ClothDRAFT_1249" /inference="protein motif:PFAM:PF00331" /note="PFAM: glycoside hydrolase family 10; Carbohydrate-binding CenC domain protein; putative esterase; cellulosome protein dockerin type I; SMART: glycoside hydrolase family 10; KEGG: scl:sce6693 O-glycosyl hydrolase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 10" /protein_id="ZP_05429388.1" /db_xref="GI:256004407" /db_xref="InterPro:IPR000801" /db_xref="InterPro:IPR001000" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR003305" /translation="MKNKRVLAKITALVVLLGVFFVLPSNISQLYADYEVVHDTFEVN FDGWCNLGVDTYLTAVENEGNNGTRGMMVINRSSASDGAYSEKGFYLDGGVEYKYSVF VKHNGTGTETFKLSVSYLDSETEEENKEVIATKDVVAGEWTEISAKYKAPKTAVNITL SITTDSTVDFIFDDVTITRKGMAEANTVYAANAVLKDMYANYFRVGSVLNSGTVNNSS IKALILREFNSITCENEMKPDATLVQSGSTNTNIRVSLNRAASILNFCAQNNIAVRGH TLVWHSQTPQWFFKDNFQDNGNWVSQSVMDQRLESYIKNMFAEIQRQYPSLNLYAYDV VNEAVSDDANRTRYYGGAREPGYGNGRSPWVQIYGDNKFIEKAFTYARKYAPANCKLY YNDYNEYWDHKRDCIASICANLYNKGLLDGVGMQSHINADMNGFSGIQNYKAALQKYI NIGCDVQITELDISTENGKFSLQQQADKYKAVFQAAVDINRTSSKGKVTAVCVWGPND ANTWLGSQNAPLLFNANNQPKPAYNAVASIIPQSEWGDGNNPAGGGGGGKPEEPDANG YYYHDTFEGSVGQWTARGPAEVLLSGRTAYKGSESLLVRNRTAAWNGAQRALNPRTFV PGNTYCFSVVASFIEGASSTTFCMKLQYVDGSGTQRYDTIDMKTVGPNQWVHLYNPQY RIPSDATDMYVYVETADDTINFYIDEAIGAVAGTVIEGPAPQPTQPPVLLGDVNGDGT INSTDLTMLKRSVLRAITLTDDAKARADVDKNGSINSTDVLLLSRYLLRVIDKFPVAE NPSSSFKYESAVQYRPAPDSYLNPCPQAGRIVKETYTGINGTKSLNVYLPYGYDPNKK YNIFYLMHGGGENENTIFSNDVKLQNILDHAIMNGELEPLIVVTPTFNGGNCTAQNFY QEFRQNVIPFVESKYSTYAESTTPQGIAASRMHRGFGGFSMGGLTTWYVMVNCLDYVA YFMPLSGDYWYGNSPQDKANSIAEAINRSGLSKREYFVFAATGSEDIAYANMNPQIEA MKALPHFDYTSDFSKGNFYFLVAPGATHWWGYVRHYIYDALPYFFHE" sig_peptide complement(68394..68492) /locus_tag="ClothDRAFT_1249" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.972) with cleavage site probability 0.603 at residue 33" misc_feature complement(67992..68321) /locus_tag="ClothDRAFT_1249" /note="Carbohydrate binding domain; Region: CBM_4_9; pfam02018" /db_xref="CDD:145283" misc_feature complement(66879..67910) /locus_tag="ClothDRAFT_1249" /note="Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495" /db_xref="CDD:154432" misc_feature complement(66393..66800) /locus_tag="ClothDRAFT_1249" /note="Carbohydrate binding domain; Region: CBM_4_9; pfam02018" /db_xref="CDD:145283" misc_feature complement(66240..66293) /locus_tag="ClothDRAFT_1249" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature complement(<65535..66023) /locus_tag="ClothDRAFT_1249" /note="Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031" /db_xref="CDD:187168" misc_feature complement(65271..65966) /locus_tag="ClothDRAFT_1249" /note="Putative esterase; Region: Esterase; pfam00756" /db_xref="CDD:144380" gene 69018..71552 /locus_tag="ClothDRAFT_1250" CDS 69018..71552 /locus_tag="ClothDRAFT_1250" /inference="protein motif:COG:COG5373" /note="KEGG: glo:Glov_1094 hypothetical protein" /codon_start=1 /transl_table=11 /product="membrane protein-like protein" /protein_id="ZP_05429389.1" /db_xref="GI:256004408" /translation="MTNNLKIILAKQKEIITSLENEIAGIEANDLVKENQKLKEELAK LKSSLEKEKIENEKLSKENKNLRNILYEQFYNEKISLLNSAEKRMDVYYRAHVEGEIN RLTRFELSVKRRIDEMTKVLRANRVSLQDEIYIKLEELRNLLNVKITKAREEIMQQTG AFIQNRNEGLARLRQEQVTEQEIKARAKQNNIESIIGLNIINKVGIFLLIVGVITAAQ FTYFRLPDTLKSVFTFAVGVVLLIAGEILNRKKPNVFSLGITSGGIAILYVALCLSYF QFKLLETYPALGLCILITAGTFVLSQRYNSQTISAFALIGGYLPIFSITGISAIAYGA MVYFVILNLLALIIAVNKKWAVTAYIGFVLNVIGSVYIASIMFGGLFAPSEFSFDSVI TIIYILFAFVIYTLIPIAGTFRQKLSFKTSDIVLLALNTFISSVLLYWSFYASDLEDF TGLFALTFAIIYLALGRFIEKNMPKEKQVTALFYLTGLTFVVLIIPFQFGKVWLSLGW LIEGVALLSYGICKEIKRFKKAGIAISFLCLLTFLSFDVSLIQDSLFTFKYFAITLGS IIILGALIYKKNLASKESKLFKYATSINLLIFLLYIISNELKPFLSQYVQDTKFDLDY LICSAMILTSFLVAYTLPRIKVLCDNVIKGISMSIYALALLTLFSLNFTSPVKGYLVE MPLAISIVGTLELALIAFLSILAVRDLVLYFVIDHKLGIEWYPLAISLYFVIILTQNL ITQYRLEFSNAAISIIYLAAALTWIIFGFAKRYVFIRRFGLAMSMLSVAKLFIIDLAF LTQGYRIVSYFVFGIILLAISFVYQYFNKKLENICEVMPDDKKNSN" misc_feature 69603..>70829 /locus_tag="ClothDRAFT_1250" /note="Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101" /db_xref="CDD:150741" misc_feature <71343..71510 /locus_tag="ClothDRAFT_1250" /note="Predicted membrane protein [Function unknown]; Region: COG5373" /db_xref="CDD:34937" gene 71530..72732 /locus_tag="ClothDRAFT_1251" CDS 71530..72732 /locus_tag="ClothDRAFT_1251" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: nis:NIS_1344 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429390.1" /db_xref="GI:256004409" /translation="MIKRIVISLLLFILLFVSNAYAVDFSYSARIENGGSKKYKAIRI TPKIYNNINANMADLVLYDESNEPVPYFINSFKEIKTETQKSYAMKLVNSFVKDEYYY LDYALEEFPDEDIIATSIEIKTENSGFAKRVEVFGSYDNVNWEKVKEDILYSVEGIKK LEIQFDSIKKYTHYRFKISNNLEKISFSSVELKYNLVYHEKEYFTETLSPEYNVAEQE NKTVIKIKDLKNLKVTGITLKTDSTFKREVTFDGRISKTLYNLNFNGMQYTDLTIAVE PYRITSDTAELVIDNKDDKPINVEGIEIEYLFDELVFEGSGSKEYVLKFGNNEILTPK SYDISNYKEYILDEGYDILNIREIVELPRKEPETKPPEYDYKLIFNISIILVAVIMAV IIFLKIKK" sig_peptide 71530..71598 /locus_tag="ClothDRAFT_1251" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 23" gene 72824..73708 /locus_tag="ClothDRAFT_1252" CDS 72824..73708 /locus_tag="ClothDRAFT_1252" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429391.1" /db_xref="GI:256004410" /translation="MSNTSNTHINLENGRLNVEIARPGSVYNGSRFDWTAFITKIVLD NKYSFCAPESEIPGQGSGGFGLCNEFGINTPIGYDEAKPQEKFPKLGTGLLTRPDESD YFFFDKYEVEPFPVKISADKNAVVFDVEPVNCNGYAVKMTKTVSIEGNILTIDYHLEN VGSKPIKTEEYCHNFISVNNKRIGDGYVLKFPYNIKPKEIPEVMNIKGNEIRWNFVPK GDFYCQIEGFKPGEKHYWELLYEPERVGIREYSEFEIVKVAVWGTTHVVSPEVFINVD IAPGKTQEWRRQYEFFTY" gene complement(73831..75573) /locus_tag="ClothDRAFT_1253" CDS complement(73831..75573) /locus_tag="ClothDRAFT_1253" /EC_number="6.1.1.18" /inference="protein motif:TFAM:TIGR00440" /note="KEGG: sfu:Sfum_3516 glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase class Ic" /codon_start=1 /transl_table=11 /product="glutaminyl-tRNA synthetase" /protein_id="ZP_05429392.1" /db_xref="GI:256004411" /db_xref="InterPro:IPR000924" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002016" /db_xref="InterPro:IPR004514" /translation="MDAQVDGKANELNSTEENEKVYSNFIQDIIDEDNRTNRYGGRVH TRFPPEPNGYLHIGHAKSICLNFGIAEQNGGLCNLRFDDTNPSKEDTEYVESIKADVK WLGFDWEDRLYYASDYFDKMFEYAVKLIKMGKAYVCDLSADEIREYRGTLTEPGKESP YRNRSVEENLDLFMRMKNGEFEEGSRVLRAKIDMASPNLNMRDPVIYRIIKASHHRSG DKWCIYPMYDFAHPISDSLEGITHSICTLEFEDHRPLYNWVLETLDMECKTRQIEFAR LNLTYTVMSKRKLLRLVQEGHVRGWDDPRMPTISGLRRRGYTPSAIRNFCARIGVAKS NSTVDISLLEHCIREELNQKAQRVMAVLRPLKLVIDNYPEGMVEEFEVENNPEDPNAG TRKVPFSKVLYIEKDDFCENPPKKYFRLAPGQEVRLKGAYIVKCVDVVKDDKTGEITE VHCTYDPQSRGGNASDGRKVKGTIHWVSAAHAIDAEVRLYDHLFSVPNPGADENVDFI EQLNPNSLEVLKSCKLEPSLAGAKPGDAFQFLRLGYFCVDLVDSKEGSLVFNRTVTLK DTWAKIASKEKEDK" misc_feature complement(73858..75537) /locus_tag="ClothDRAFT_1253" /note="glutaminyl-tRNA synthetase; Provisional; Region: PRK05347" /db_xref="CDD:180031" misc_feature complement(<75163..75450) /locus_tag="ClothDRAFT_1253" /note="nucleotidyl transferase superfamily; Region: nt_trans; cl00015" /db_xref="CDD:185776" misc_feature complement(75397..75408) /locus_tag="ClothDRAFT_1253" /note="HIGH motif; other site" /db_xref="CDD:173912" misc_feature complement(75397..75408) /locus_tag="ClothDRAFT_1253" /note="active site" /db_xref="CDD:173912" misc_feature complement(order(75397..75399,75406..75408)) /locus_tag="ClothDRAFT_1253" /note="nucleotide binding site; other site" /db_xref="CDD:173912" misc_feature complement(74503..>74934) /locus_tag="ClothDRAFT_1253" /note="catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807" /db_xref="CDD:185676" misc_feature complement(74713..74727) /locus_tag="ClothDRAFT_1253" /note="KMSKS motif; other site" /db_xref="CDD:185676" misc_feature complement(73930..74511) /locus_tag="ClothDRAFT_1253" /note="tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950" /db_xref="CDD:146533" gene complement(75997..>80959) /locus_tag="ClothDRAFT_1254" CDS complement(75997..>80959) /locus_tag="ClothDRAFT_1254" /inference="protein motif:PFAM:PF00404" /note="PFAM: cellulosome protein dockerin type I; KEGG: antigen 332" /codon_start=2 /transl_table=11 /product="cellulosome protein dockerin type I" /protein_id="ZP_05429393.1" /db_xref="GI:256004412" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="QTEDSKVISEGVLEVKGDFTQIACGVTPSFYACENHKVILSGEG QQIITMEESNSRFNELILINPIEDGNYIFVPEGRTFWNSLEIDLDYNQSKKIHQYWVT IEKKNDTVAIGDTIDIRMRGEENSKAEALVYYKCISKTGSADEKVITVPMKEYGPGKY QAYFKVTEDIDQIQKIQINLLDAEGNLYTKTLGKEKEGFPLEVGATVSIDLSGVSKLE KFAGMDLVLESKGLNEQARRKITGDTLYTITNLKPADDYRLAIESKNGFTAGTIENIS ISKGINDSIIVKLIEEPAKLTVIVTDDEGNIVESGYNLTFYDPARNFKQVGTGKELEH IFVGKEISVGLTLKEELGKKFKNPVEKYNVAIDKRESVLTLRLEKLKIITLTGIIVED ETGIPVQNANINVSQLLNNQFGNYIKLVTDNAGRFSIEVAMGKTTLGISHEQYMNLEL KAFDESTEINGDSLDLGEIQLTPYKGRLTLELLKKPAHTSQEEPGLEQENLYNYTISI YNKTKQAKIKNFNIKPPYIFLNDTNIETGDVIEVTFTHKKDYTLPATIELTLDRLMNA SGQAVAKENGKGMASIQSGNQRCELMVYNSDKKFIESCSMNREGKIISNPLKEGVYTF VFISSNNYLWRLNTLEQFEEIGLKEGIHFVKKEVEIKNGEIKDLGLIVVPELNEKELF FTDPDVASYAVVSENNRIGKDIVLRAKYSFRKPIESQTVKLLFRVPDQTFYVKDTLTI DGELVDSVNVSGSFIEVTTTKTEGVVRFNIRPTEAVVCYSNAYVEFKAEGRTVREPLG VVNEVVPYLTIGAPNVTSLEKVYVTGQTLPNLEVKIYDEGSLVGVTKANSTGAWNFQV SLGKDKSYSVHNLSARIEYNDQVIESETLEVIYKKSVPEIEKVTTIHSNQSLILYKNG EIVPKGVYTYVPSQSYTFIVDFVGDSAEEIENLCIVSNRNGEERKLDAKYDPQSKSWI ATGSFGYNHVPGSFTVEYNLKKKRLIKEDGELNLEVLEQISTFADQFLYELKKENVMV GLLDENEIGFMLKEDTGGIAIVTIVIGDQPIEREKYEKMGYLFKEIDGKLGAVLLIKD ETENKIFTSKVRLASNKTEDSVKSEDDDESSQKETPLVTKDERISMAATIIGELGNIA GSGKVVEAIDFISGIGTAVNTIAFTPANAVTDMGYVQKKLQESENISSEDKERLRDDL FLASGVYNFTVNANFIASLMDGHTRNGTMHKIIDIVIDKYDQYSLGDKLWEDIFGKNE DDRESGKSTKSGKGSSIKLPLQEQKTLVDPSGYVYETVPDNRITDATVTVYYKDENGE MILWNAEEFGQKNPLLTDENGFYAWDVPEGMWQVKVEKEGYETAYSEILPVPPVQTNV NIPLVSYEPPKVGHIYAYPEYIEIAFSKYVKHATLDSESIQLKQGENKVNIKIVYEDE EGNYSKKIKLIPAEKTSFEGKYTLNISKSITSYAGVAMQKAEIRDIEIVAEPKSIEIL DKVEIELRKTVAIEIRVLPEEAAKGKKIIVTSGMEEIVSAEDVLLDERGRGKLKLKGN LPGTVDIDLRLEGSAVEKKIQATVKFPEDNGEIIEPPVVLNGDLNRNGIVNDEDYILL KNYLLRGNKLVIDLNVADVNKDGKVNSTDCLFLKKYILGLITI" misc_feature complement(76015..76077) /locus_tag="ClothDRAFT_1254" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" ORIGIN 1 gaatggacat ggaaatacac tttccacgtc cattctttat atcttaaata ttaagtagac 61 taaaacctat tccttatttt cttcttcctc actgcaatct tcacagtcgc agtcccattc 121 aaaagctatt tcctcatggc agtaaggaca ctcaaaagaa tcactgtcac cgtctatcat 181 atcctcggta agatcaaata ctttattgca atgagggcat tctatctggg caagaacatc 241 atcatcttct tcctcatcga acaaaattct tgcaaactct tccaaatcct catcaatgct 301 gtcaacctgt tcttccaact gttcctgaac ctcttcgata tcctccacgg ccagtgcaat 361 atcatcaagt acttcaatca ttgctttgag cagctttcct tcattggttg aatcatcgat 421 tttcatgcct tccgcaagtc cctttaaata tgagaccctt tcctttatat agctcataaa 481 ttacctcccg tacactatat taattaacct ctgcacataa agtataacca ggtctgcctt 541 taatacaaat taagttggaa gtgactttat acattgtctt aacttccaac ccaaatatat 601 tataaccgtt atactctttc catatactct cctgttctgg tatcaattct aataatatct 661 cccttgttga caaacaatgg aaccttaatg gacgctcctg tctcgacaat ggcaggcttg 721 gtcgcaccgg tggccgtatc acctttaaaa ccgggttctg tatcggttac ttcaagttca 781 acaaagttag gaggctctat tccgaaaaca ttccctttgt gggaaagaac ttttactatc 841 tcattttctt ttacaaactt gagagcatca ccgattttgt ctttgcccaa aggcagctgc 901 tcaaaggttt ctgtatccat gaaataatac aggtcgccgt cattatacaa atactgcatg 961 tcctttcttt cgatatgggc ctttggcatc ttgtccgtcg ggttaaaagt tttctctata 1021 gtagcacctg ttactatatt tttcagttta gtccttacaa aagcagctcc cttacccggt 1081 ttgacgtgct ggaactcaat aacctgaaat atctgcccat cgagctcaaa agtcactcca 1141 tttttaaaat caccagctga aatcatctaa aatccctcca aaaaatattt cttaaaatac 1201 ataagttaca ggcccactca atccttgtac cattaagctg agctacactc caacttatgc 1261 atgtttttat tgtcttcata aataatctgt tattataaac ccatagttaa tattaaatta 1321 aaatcgtgac tatttcaaga taaaattttc ttttaatagt aaaaatataa actttatggc 1381 cctacaatac tatcatgtcc tttttggatg ctgtcaaaac atcaggatgg tctccattaa 1441 ttactatcat atcctcaatt cttacgccac ctaggccgtt cacataaata ccgggctcta 1501 cggtaacaac catgccgtca tccattacca catctcccaa cggtgaaagt ctgggttctt 1561 catggatttc aatgcccaca ccgtgtccca atccatggcc gaagttgaat ccaaagcctt 1621 ccctgtaaat tatttctctt gcaacagcat caattttttt gcctgtcaaa ccctttacag 1681 caccttcaag agcagctttc tgggcggtaa gaacggtatt gtaaatcttt acaagttctt 1741 ctttcggctt tcccacaaaa accgttcttg tcatatccga gcaatatcct ttaaacaccg 1801 ctccaaaatc catcgttaca acgtctccat gctcaattac cttttctgag gctactccgt 1861 ggggaagtgc cgagcgtact cccgatgcaa ctatcgtttc aaaagatgta cctttagccc 1921 cttgtttttt catgaaatat tccagctctg cggcaatctc tatctccctt actccgggtt 1981 taataaattc caatatgtgg ctgaaagcat tatccgcaat ttcaacggcc ttttttataa 2041 tttccagctc cattttgtcc tttttcattc tcataacttc aaccatgcct tcaaggggct 2101 ttaactcttt gaccgaaaac ttttcctcaa attctttgaa ctttttatat gttatatagt 2161 cttcctcaaa tcccagtatt tcaatgtttt ttgactttaa aatcccgttt aggaaagaat 2221 aaatattgtc gctatactcc atcacttcaa aaagaggggc ctcaagtctt gcctgttccc 2281 tgtatctaaa atccgtcacc agcacggcat catcccgggt aattacaaga tatgcaaaag 2341 aacctgtaaa tccggaaaga taaaaatagt ttggactttt tgcaattatt gcggcgtcaa 2401 ttcccttttc tttaagcttc gctctaaaat tttcaagtct ttttcccata taattttcca 2461 ttgaatcacc tttttcctaa aaataaaatt tgcagttttt aaataaacat gtcatgtcaa 2521 caacatgtca tgttaataat atgtcatatc atcagagcgg catgaagggc aagtatgtac 2581 cctgcacttc caaatccact gatttgcccc acacacacag gagcaattac cgatttgctt 2641 ctaaactcct ctcttgcatg tatgtttgac agatgaagct caatagtcgg aatttcaacg 2701 gcttttatgg catctcttat tgcaatgctg tagtgagtgt atgccccggg atttattatt 2761 atgacatcaa tttttcccct tgattcatgt atcttgtcta ttatctcccc ctcatgattg 2821 ctttgaacaa aacttaaatc aacatttaat ttttccgctt ccgcgttcat tttcctggct 2881 atgtcctcca aagtctcttc accgtaaata ttcttttccc tgatccctaa aaggtttaaa 2941 ttgggaccgt taattacaag cacttttttc attttgcatc ccctctgcaa ctttattata 3001 tattttctta agctttaaag catcttcagc catgttggcc ctggattcgc aaataatgac 3061 cggattcata ttctttttca aaatcacctc ggccaaatgt tcaaactcag gaccaaactg 3121 cgtgtcatca atgttccagt gttttttctc tccgcctttt gtaaattcaa ttctgctgaa 3181 gtggcagtga agctccctaa ctttctcggt tcccagagaa ttttccagca tatttattat 3241 tctttcaaaa tcctccacgg tattaaggct tccctgtcct cttgcatgaa tatgcccgaa 3301 atcaatcgtc ggaaagagcc tttcattggt tttgcatatt tcaattattt cttccaaaga 3361 accaatctgg ttgttctttc ccaaaacctc cgggcaaagt actatatctg taaggccaag 3421 actgtccgcc tcttttagca cctcatcgaa aagtttggcg gatatctcaa gggcccattt 3481 tttatcaacc ttgctgtatg agccggtgtg aaccactatc ctttttgccc ccatccattt 3541 tgcgagcctc atgcaatcaa ttatatatcc tttggacttt attctttttt cctcctcagg 3601 acttgccatg tttatataat aaggagcgtg tatgctcaaa aatatattgt acttttgagc 3661 ctcttgtcct attttttcag ccaattcctt tccaatatta acacctctgt tgcactgata 3721 ctcataagca tcaagcccca tcccggacaa ccacgccggc atttcagcag aggatttgtg 3781 gccctctttg taaaagcttt cagaattacc tgaaggtcca aaccttacca agacaatcac 3841 ccataaaaaa tattatgctt caatcgtaaa gattaaagca taatattatt ataactaatg 3901 attaaccgtt ttaaaactgt attgttaacc acaatcgttt tttgtgacca aatcactcat 3961 gccttggatt tctcttgact atcaccgcag ctttggccaa ggcggaaatc acatccactt 4021 caaactgctg ttttaaagaa tcgaccttcg aataaagttc tcctttgtca gtcacaatgt 4081 atttcggagg taaattattg agcgctatgg cagctatatc cattctgcac ttttcacagc 4141 tgcacacatt aatatcacta agcacgtcct tcatcagcga aaaaactacc tcttccatat 4201 aattttttat ttgactcatt ttaattttcc tcctcttttg gcagtttgac tgctatacag 4261 tttttggaga gcaaatttcc ttaaatatca tatgcatggt ttatataata atatcggtca 4321 catgcacaac catcttaatt cttttactct tttacttaat tcgtctaaag tttcctgatt 4381 taaacccatg ttttctcact catacatgaa gcaaagtgct caggtaccat tccaatagct 4441 cccagccaaa aagataagtg aaaaaagtac ccattacaat aaaaggaccg aaaacaaacg 4501 tactccttct ctccttcttc ttaagcaaaa gtaatacaat acttacaatt ccggccgaca 4561 caaaggatat aaaaagtgcc actatagtca ttttccagcc caggaaaagg cctatcggag 4621 caaacagctt gacatcgccg ccgcccattg cctcatccgt tttataaacc aaataaccta 4681 caattgccac cagaagcaaa aagccaaatc ctataaacgc acccaacaga ggattccacc 4741 atttgcgatc cacataaata tccatgggcc tgaaaatatt ataaacaaaa ggcagaactc 4801 ctccaaccag agccgctact acaagcttgt tgggaataat catatgatcc aaatcaataa 4861 agaatacggc tataagtact gacataagat aagcagatgc caaaaaatcc accgccaacc 4921 catacttcca gaacaaaagc aaataaacaa cggacgttaa aagttcaacc aaagcatatc 4981 ttggagaaat cttttcgccg cagtatctgc atctgccttt taaaaacaga taactgaaaa 5041 caggaactaa atccaacgca ccaagcgtat gtccgcattt catgcagtgg gatcgaggcc 5101 tgacaacaga ttcatcgttg ggtattctgt agatacagac atttaaaaat gaaccgacca 5161 gaagcccaag caaggccact gaaatgtaac aaaaaaccgt aaatcccgtt tcaaacaaca 5221 gtccaagatt taatgaagtc cccatcttct atacctcttt tgttttttat tttctaaaaa 5281 actttagcat agaattatta tatagtaaga taatagaaat ttaaagcatt ttataattct 5341 tcttcaaaag acagcattct tgacatctca aaagcagtgg tttttccctc aagaacaagc 5401 tgttttgcat tttcttttaa agttttcatt ccccttaaaa cacaaaattt tctcaatttc 5461 tcctttgcaa agttttcctt catcatatcc ctgaagctct tgtccacatt cagcacctca 5521 aaaacaccca atttcccttt gtatccggta ccggaacatt ctgcgcaccc atttcccgaa 5581 tacagttcga cgggtctgtc cagttcaaga agtgaaagtt cctcatctgt tgcaacatac 5641 ttctttatgc agttgggaca aatttttctc acaagccttt gagaaattac ccctatcagg 5701 gacgatgcaa taaaaaacgg atctattccc atttccacaa gagttaacac tgcgtccaaa 5761 gtatcattgg cacaaaaagc tccaagtaca agatgccctc ccattgccgc ctttacagct 5821 atttcagccg ttttcgcatc ctttatgtcc ccaatgacaa ttacatccgg tccctgttct 5881 aaaattgaac ttagaccttt ttcataagtc aggcctgtct tcatgttgac ctgtacctgg 5941 tttactcctt caataacgta ttcaacaggg tcttcaatgg taattatatg tacattcgga 6001 ctgttgattt cacttacggc ggaatacaaa gttgtggttt tgccgcttcc ttcaggacct 6061 gttatcaaaa ccaatccttt aggacttttt atcattctct caaattttac gaggtcctcc 6121 tgacaaattc ccagctgctc ttttggaatg acggaagtct ttttatgaac aatacggatt 6181 gcaattttct ctccaaaaac ggtcggaaga atcgacacct taagattgta atctcttccg 6241 tccagactta ccttcaccct gccgtcctgc ggaactgcct tttcgttcat attcataccg 6301 caaattgcct ttatctttgc caaaacacca tttagcatgc caatttccgt tctcatgacc 6361 tcatgcattt gtccgtcggt tctaaacctt atttttaatg cattttgcaa aggttcaata 6421 tgtatatctc cggacccgtt tcttatcgcc tgctctatta tggaatttaa aagcattgag 6481 gcagattcat tttccgcctc aacgctttca agctctattg tttcctcatc aattttaaat 6541 aaaattcctt tttcctttac aggctccacc aaaacatgct gtgttctgta atatttgtca 6601 atggcatttt ttattgacga cgcaaaatca actacaggct caactctcat acctgtataa 6661 tcctcaatat catcaatggc aaaaacattt aaaggatcgc tcatggcaac cctaagaact 6721 ccgtcttttt gtgctatagg aatcaattca taccttctgg caagtttttc ggggattaag 6781 ctgcaaacag cgggatcaat gttgcattct tccaatgcca cacgtaaaac acctattttt 6841 tcctccagga ccctcattat gtcctcctgg gtcacaattc cttcagaaac cagcaaaact 6901 ccaagttttt ggcctgtttt tttctgaagt tttaaagctt tatccagctg ctcttttgaa 6961 ataagcccgg cttccactaa aatgtcgcca agaccttttc ttttttgttt ttgcataaac 7021 tccctccctg gatttcaatc cccggcactt gtacggaaat cttgcatgca aatatacaaa 7081 ctgccttcat ttcactgtct ttgttttttt attatttggc tgatttaagc tgcaaatatt 7141 ttttgaaaga ttcataaaca cttttaagtt tatcctcggt aaactttaca cccgtccaga 7201 tttcataggc gcttatccct tgatagaaaa gcattccaag gccatttatg atttttgccc 7261 ctcttttttc agcatcattg agaaatttgg ttttttcagg attgtagatc acatcataca 7321 ctatttgatt tttgttgaag cactcagtga atttaacggg ggtttcccgg gttttaggat 7381 acatacctac agaagttgta ttaataataa tatcactttc ctcaaaagcc attctgaaag 7441 ttttatcttc aaaattgtac acctggacta tttcttttat attttcattt acaacctcgg 7501 caagttcaac ggatttctcg acggtacggt ttacaacact gattttttcc gcatcttcag 7561 aggcaatttt aacggcaatt gcccgggcca ctcctccggc tcctataagt acaacctttt 7621 tgcctttaaa gcccacaccg gcttcttcct taaaagatct taaaaaacct tccgcatcgg 7681 tattataacc gtacagacga ccgtcaatct tttttaccgt gtttaccgct cccatgagta 7741 ttgcttcttt tgaattctcg tcaagatatt tcattatgtc ccttttgtaa ggaattgtaa 7801 cgttaaaacc tataaaatcc aaagctttga gagcttttac cactgtctca aggtcttctt 7861 ttccaactgc cagaggtatg taaacaatat ccagtcccag cagcgaactt aacgtattgt 7921 gaagttgggg tgatatggaa tgctcaacag gatttcctac aagtcccaac aattttgtct 7981 ttcccgttac cctgacatcg atatccataa tctttcctct ctccattatt cagtttattt 8041 tacaatttta ttttaaattt gttttcgggt tttcattttt gcaagaacaa acttttcagc 8101 tattcttttc agtctgacaa aaaagtattc tcttttatct atcggtgtaa ccagtatggt 8161 aaacatatta accttgtttc ccccatatat atcggtaaaa atctgatctc ctattacagc 8221 cgtttccgaa gctttggtat tcattatctc catagctttc acaaacgacc tgcttctggg 8281 cttcgaggcc ctgtggatga cgtcaacatt aagtttgctg ttaaatctgg ccacacgctt 8341 ttcggaagca tttgacacaa tgcaaacctt aaatcccttt ttcttaactt tgtcaatcca 8401 ggctatcgta ttttcatccg cttcttccac atgctcaggt acaagggtgt tgtctatgtc 8461 aagaataagc ccttttatat ttttttcagc caggaaatcc aaatctatat cctgcactct 8521 gtctgcctgc aaatcaggat aaaacttttc taacatttca ctcctccagg ttcattatgc 8581 tattcataaa tatgataaac acaccaatca acaaactata actataataa caataatgta 8641 acagtatagc aataaaaacg ttgcaccagg ttgaattatt tttttctcaa attttaaaag 8701 tactggattt ttaaaaaaaa agtagcataa tagaatataa gatttggagt aaagaattaa 8761 ttcatcagta ttatgatatg cgcaaagaaa tattggaata ttcaaattcc aaatattttt 8821 atcttaatgt tattattgaa aggggttaaa tagatatgtc ctaccaaatc agtattcaaa 8881 aaacacaaaa tccaaaaaac aaacctgacc aggataacct aggctttggc cagattttta 8941 ccgatcacat gtttataatg gactatactg aaggaaaggg ctggcatgat ccaagaattg 9001 ttccatacgg ccctctttct ttggaaccca gcacaatggt atttcattat ggtcaggcag 9061 tttttgaagg tctgaaagct tacaaaacag aggatggaag aatccttctt ttcagaccaa 9121 gaaaaaacat ggagagaata aatatttcaa atgaaagagt ttgcataccg aaaatagacg 9181 ttgattttgc cgtagaggca tgcaaaactc ttgtaagtgt cgacagagac tggattccgg 9241 aagctgaagg cacttctctt tatatacgcc cgtttataat ctctaccgat cctttcttag 9301 gagtaagacc gtcctggaca tacaaattca taattatttt atctcctgta ggagcttatt 9361 ataaagaggg aatcaatccc gtaaaaatat acgttgaaag cgagtacgta cgtgccgtaa 9421 agggaggcac aggttatgca aagactcccg gcaactatgc cgcaagtctc atagcgcagg 9481 ttaaagcaaa ggaactgggt tacacccagg tactctggct tgacggagtt gagaaaaagt 9541 acatagaaga agtaggtaca atgaatgtgt tctttaaaat aaacggcgaa gtcatcactc 9601 cttcccttga cggaagcatc cttgccggaa taacccgtga atctacaatt gagctgctta 9661 gagcatccgg cataaaagta actgaaagaa aaataaccat agaggaaatt tacaatgctc 9721 atgaagcggg aactttagag gaggcttttg gaaccggaac tgctgcggta atttcgccta 9781 tcggcgaatt aagctggaac ggcaaggtta taaaaataaa tgacggtaaa atcggagaaa 9841 cagcctcgtt tgtttacaat accatcacag gcattcaaag cggcaagatc gaagacaagt 9901 tcggatggac cgttgaagta aaataatgat aatattgttt ttggaaagca ggtgattact 9961 cacctgcttt tttatacgtt tttatactga ataaaaaaat taaccaaaaa tatcattgtg 10021 atagatgact gttatagtat ataatataaa atgtacttaa aaaaaattta atacttgcaa 10081 aatcactgta aaaatactaa ttttcgacat cgtcctaatc aattccgttg aaaggatgtt 10141 taagtttggt cttgccgccg gaaacaagtc tcaattcaac aaattatttt tatttaccgg 10201 aagggggttt tccaattgtt tgattttgtt cacaacattg atatctgggc agcaatctcc 10261 tttatacttg gttttatttt tgtgataatc gaaatgtttt tccccggttt cggtttaccg 10321 ggtgttgtgg gtctgatttt tctttttata ggcattgtgt tgacggctaa aacgctcacg 10381 gacgtccttg tcctgttggc gataatactt ttgatactgg ctgttgtcct tgccatagca 10441 gttcgatctg cctcaaaagg acgccttaaa aaactggtac ttaccgattc tttggaaaag 10501 gagagcggat ttgagggaac cgaagacttt acgtcatttc tcggcaagga aggagtggct 10561 ctgacagctc tgcgcccggc aggcactgca gagtttgacg gagtaaaact tgatgttgta 10621 tcagaatttg actttattga aaaagatgca aaagtaaaaa ttgttaaagt tgaaggtcgg 10681 cgtatagtgg taagaaaaat cgattaatac tttaatattg ggtcaatact gggttgttgt 10741 acaccagtgg agttgtatga tgtaacaata tttaacataa caacaaaaat atgaaaggag 10801 agttttatta tggatggtat agctttcatt cttattgtag gagcaataat agtatttatc 10861 tcactgtttt ttgcaattgt tcctgttggt ctttggattt cggcatttgc cgcaaacgtc 10921 agggtcagca tattcaccct aataggaatg cgccttagaa gagtcgttcc ttcaagagtt 10981 ataaatccgc ttattaaagc tacaaaagca ggtatcaatg tgtccatcaa caaacttgaa 11041 gcccattatc ttgcaggcgg taatgtggac agggttgtaa atgctcttat tgccgctcaa 11101 agagccaata tccctcttga atttgaaaga gccgctgcta tcgaccttgc cggaagaaat 11161 gttcttgaag ccgttcaaat gagtgttaac ccaaaagtta ttgaaacacc agtcgtggca 11221 gcaatagcaa aagacggtat tgaacttcgg gcaaaagcaa gagtcactgt cagagcaaat 11281 attgaccgtc tcgtcggagg tgccggtgaa caaaccatca ttgcccgtgt cggcgaaggt 11341 gttgttacga cagttggttc cgctacggac cacaaacagg ttctcgaaaa tcctgatgcc 11401 atatccaaaa cagtgttaag caaaggtctt gatgcaggta ccgcttttga aattctttcc 11461 attgatattg cagacattga cgtgggaaga aatgtcggtg cccagctgca gacagaccag 11521 gcggaagcgg ataaacgtat tgcccaggca aaagctgaag aaagaagagc tatggctgtt 11581 gcaagggaac aggaaatgaa agccatggta caggaaatga gagcaaaagt tgtggaagcc 11641 gaagcggaag tgccaaaagc actggctgct gctcttcgcg aaggaaaaat cggtgtcctt 11701 gactactatc atttacaaaa tctcatagca gacacccaaa tgagagacag tatttcaaaa 11761 atgagcaaac atgatgattc ttcatctgac aaaaaatagt taggtttaac gtttcaccgc 11821 cgtcctggtc caataaaaag gagctgtttt gttatgagta tgaataaaga tttattatta 11881 agtttgctgg aaacacttgc agaacaatct aaaaacgcaa acaacactaa aatgcggcaa 11941 tataatactg caaacaaaaa tcctcacaat tattcaacaa ggccggttca aagagcttct 12001 cataattccg gcgcccacgc aaaaccaagg ccaaatgtga gccatgttgc aaaggagcac 12061 tattttgaag gaagtcacaa tcttgaggaa agctcagact ttgaaggaat aggtcaaggt 12121 tctttggact atgccagttc agaaggagtg ggacaaggtt ctttagatta caccagttct 12181 gaaggaaaac cgggttttca gggttctccc ggtttagaag gctctttaag ttccgaaggt 12241 gacggcagac actcaaaaaa caatattgtg acaccggaga ctccttccca aactgcatct 12301 tttaatcttt ctgaaatcag taaaaatgac atagttcgcg gaataatttt atcggaaatt 12361 ttgtcaaaac ccaaagcact cagaagaaac caatggtaaa ttgaaatcat aaaattcaag 12421 atgtcaaaaa ctttttagtg cgtaaaatac aaaagcaaat ccgggtgaaa ttcccggatt 12481 tacttgtttt tgcaacactt gatatatatt tcaagctcaa tataaatttc aatatgcata 12541 aattaataat tttctgccag cacttcgaaa aatgcttttg gatgagcaca tgccggacat 12601 tttccggtgc gctgtttcct tcatgcacat aaccacagtt tctgcatttc cataaaactt 12661 tctcgtcttt attaaacacc ttgttatttt caatgttttc cgccagcttc ttgtatcttg 12721 cctcatgcct ttgctcaact tcggctattt ttgtgaaagc tgccgctatt tcatcaaaac 12781 cttcttcttt tgcaactttc gcaaattccg gataaagctt tgtccactct tcattttccc 12841 ccgctgccgc cgccttgagg ttgtccaaag tgtttccgta agccacaggg taatctgcat 12901 ttatcataat tgaagcaggc agctcaccgt tcaacccctc aagaagaaat ttgtaaaacc 12961 tttttgcatg ttccttttca ttgtcggcgg tttcattaaa aatagcctca atctgtctgt 13021 aaccttcctt attggcaaca gaagcgtaaa aattgtacct tgtgcgagcc tgggattctc 13081 cggcaaacgc cttcataaga ttttccattg tttttgtgtt tttaagactt ttcatctggt 13141 acctccccaa tagttataat ttgtgcttga catcacaatt ttaccataac ctctaaaaat 13201 aaagcaactg ccctcaatct tacgacattt ctttacaaag atttacaaaa ataacatttt 13261 agtattacat tatttttaaa tataccttaa aattaaaaat tttttaccct taatgttcaa 13321 ttatatgata aaattaaatg tatgctagaa taaagacaga cagataaaat atcgttaaaa 13381 attgtaaata tagttgattg ttaaggggtt tttgcaaatg ggtcaaaaaa aaatattttc 13441 aaagaaaaag aatttaactt ttaaaaaagc cctgctcatt tggatggtta gtttgatagt 13501 tttaggggga atgatttttc ttttgggaaa attcgttcta agtgacagca acggcagttc 13561 agacgtggac aatgacctta catatccacc tgttaaaagt tacgaaccga ttagttttcc 13621 tacacccggc aaaatcggca atgacaagcc ttccgatgag gaaaactccg ataaatttca 13681 gggtctcaca aacggaatga aatatcatga aaagctggtt gacgaaagca gtcgaaacat 13741 attgttcatc gggcaggaca gaatttccgg cctgtatgat accataggta tattaagcat 13801 tgacagaaaa aacaaaaaac tgaaaataat aatgattccc cgcgacctgt atatcgatta 13861 cagttccaga gtcaaacact atttagaaga aaacggcaga ttaaacgatc ccgactttta 13921 taaaattaat gccgcgcacc ttatagggcc gtatatgaaa tatgagggaa aatttggtgc 13981 atattcaatg aattttctgg ccgaactgat caaagaaatt tttgacattg aagttcatga 14041 ctacgtaagg gttaacaccg aaggcttcgt ccaaattgtc gaccttttcg gcggtgtcga 14101 cattaacgtt ccgtacgaca tgcattacga tgacatatat caggatctcc acatccatat 14161 aaacaaagga tggaaccatc ttgacggaaa aaaagccgaa ggattcgtcc gttacaggca 14221 aagcaacgac gaaatgggaa acatcaccca ttcgatcggc gattatgaaa gaaagaaaaa 14281 ccagattaat tttataaaag catttattga gcagcatggg acaatgtcca atatcgacaa 14341 gctccccagt ctgatttcta cgttaaacaa atacatgaaa cacagcatcg gagtcggaga 14401 cgttctgaca acttacattg gctatgcaaa agatgtcgtt ctatacaaat acccgataga 14461 aacttataca gttaccggaa aagacaaata tatgaaccaa agatattata ttgtaattga 14521 aaatgacaac aagaccagca aagttgttga ctaagcttta aatcaaattg gcagcatata 14581 tttataaaaa cagtttaaat ttgttttttt tagaatttga cctttattta agttacataa 14641 attggaataa taaattcgac tgctttgtat aaattatatt tagagttttg gaatacagct 14701 aaattttgaa tccaaggagg ccatattcat gtatcctcat atacacagat ataaatttga 14761 atcaaaaaat accaacaggc ataatcacaa aataatagga tacacggata atatgattgg 14821 catagaagcc tttcatattc atgcatacta cggcatttca tcatacaatg gacacaccca 14881 ctacttttca ggattcaccg gccttcctat aaaaactgaa aacggtcata ttcacagaat 14941 agaaggtata cttgaatcgg cttcagatca cgaacatgta tacaggaatt atacagatga 15001 gaatattgag tatatttctc acagcatatt gaaacatgca tatgtttaaa cgattttttt 15061 tataacttct tgcatttttt attaaaaccc attattatat ataataaaaa tgcgaattat 15121 ttttatgtaa aaaatcgttt tttgttaatg tccaatgaat attgagcaat aacaaaaaag 15181 gcgtttcatt attttgttga tgcgcctttt tcttataatt cgctattaca gtttttggta 15241 gttgtgtgtt tttatctaca tattgaaagg ggattttact gatggttaat gacgaattac 15301 agacctattc attaacagag gtttttggtg cgaatgtgtt taatgacgcc gcaatgagag 15361 aacgccttcc caaaccggct tacaaagcat taaagaagac tatagatgaa ggaactccat 15421 tggaccggga tatagcagaa atagttgcaa acgctatgaa agactgggca atcgacaagg 15481 gggcaactca ttacacccac tggttccagc ccatgaccgg aatcacggct gaaaagcacg 15541 attcctttat ttcaccgaca tcggacggaa aagttataat ggaattctct ggaaaagaac 15601 tgataaaggg agagtccgac gcttcatctt tcccttccgg aggtttgaga gcaactttcg 15661 aggcaagagg atatacggca tgggactgta catctccggc ttttgtgaaa gacaacaccc 15721 tttatatccc gacagttttc tgctcataca acggcgaggt tttggacaaa aaaacccctc 15781 tgcttcgctc tatggaggca ctgtcaaagc aagcccttcg catactcaga cttcttggaa 15841 acacgaccgt gaaaaaagta attaccacgg taggtgccga acaggaatat tttctgattg 15901 acaaaaaact tcacgatcaa cgcaaagacc tcatctacac cggtcgtaca ctttttggag 15961 caatgcctcc aaaaggacag gaaatggacg atcattatta tggcgctttc aaggaaagaa 16021 tatctgcttt tatgaaagaa ctggaccggg agctttggaa acttggcgtt tcagcaaaaa 16081 caaaacacaa tgaggtcgca cccgcacagc acgagcttgc tccaattttc aacacggcca 16141 acattgccac cgaccacaac cagttgataa tggacactct taaaaaagtt gcgcaaaggc 16201 acggtcttgt ttgtctgctt cacgaaaaac ctttcgcagg ccttaatggt tccggaaaac 16261 acaacaactg gtctctgagt accgacgacg gtcaaaacct cctggatccg ggccgtacac 16321 ctcatgaaaa tgcacagttt ctcatattcc tgtgtgcggt aataaaggcc gtggatgaat 16381 atgcggacct tctcagatgc gctgctgcaa atgccggcaa cgaccaccgt cttggagctc 16441 atgaagcacc tccggcaata atatcaatat tccttggtga acagcttacg gatattcttg 16501 aacaaatcga gaataacgga ggagcaaaat cattaaagca ggccgcaccg ctgaaaatcg 16561 gtgtaaccac gcttcctgtc ctgcctaagg acgccaccga cagaaacaga acttctcctt 16621 ttgcatttac aggaaacaag tttgagttca gaatggttcc ttcgtcagct tcaatcgccg 16681 gcccaatttt tgtacttaac accatagttg ccgaggagct ctgccaaatt gcagacaggc 16741 ttgagaaagc tgaagacctc aatgcggaaa ttcacgcagt tctcagggaa atagtaaaaa 16801 accacaaaag aataatattc aacggaaaca attattccga agaatggatt gaagaagcca 16861 aaagaagagg tcttcccaat atacgctcaa ccgttgaggc aataaaggca ctgatagatg 16921 aaaaaaacat ccgcgtattc gaaaaacaca aggttttaaa cagaacagag ctgtattcca 16981 ggtatgaaat acttcttgaa agctatatta agacaatcaa catcgaagca ctaacaatga 17041 tagaaatgac aaagcgggat attatacctg ctgttatcgg ctatattaca aaacttgccg 17101 actcaataaa cactgtcaaa gcaacaggtg tcaatgccga caccagtgtt caggcagagc 17161 ttttgcagga agtgtcctca cttcttgccg aacttaaaaa gaacttggcc gctcttgaaa 17221 aatcgacttc agaggcagca gatttcagcg gtgacacata caaaaaagca tgtatgtaca 17281 gggatgatgt gttcgtcaga atgaatgaac tcagagccgt ggctgacaaa ctcgaaacac 17341 tggttgattc aaaaatgtgg ccgttcccga catacggcga ccttctcttt aacgtgtaat 17401 aatctttacc gtataagaat taaaaataag aattaaaaat caaaacaatc aaaaaaaggc 17461 cctcctctca ataaggaggg ctttatcaat gatttcacat taaaatgcaa aaaagccgta 17521 tttcgaattt aataatgttt aatattaatt aataatgctt aatatcaaat aattgtagca 17581 ttaattaagc attaacattc atactgcata ccaaactcaa gagctttcat ctcttcagga 17641 atcagattat gctttttgct cggtaacgtc tttcttaagg ctatttcaaa gttttctttg 17701 gacactatat tggtaagagc aataagtttc cccaaaagaa ttatattggc aaaagtggga 17761 tttcccattt taaaagctgt ctcggtggca ggaacaccgt aaaccttcac atctgttctt 17821 gccggttccc tttgaaccag ggaactgtcc tttataatta ttcctccgct ttccacgtaa 17881 ctttcaaact tgtccaggga tggaccgttc ataacaatca aagttgtagc actgtttaaa 17941 atcggagaac ctattacatc gtcggaaatt ataacgttgc aattggcggt accgcccctc 18001 atttcaggac cgtaagacgg aagccatgat acattcttgt tctccaacat tccagcgtaa 18061 gcaagaattc ttcccgccga cagtatccct tgtccgccga aacctgccat aataatctgc 18121 tgatccgcca ttttcattta cacctccaaa tccttgcctt tgtaattgcc caacggataa 18181 accggaatca tcttctcctc tatccatttc aatgcttcca caggacttaa tccccagttt 18241 gtcggacagg atgacagcac ttcaacaatc gagaaaccca ggtttgccat ctgaacttta 18301 aatgccttct ttattgcctt ctttgcattc ataatatttt ttatgtcatg caccgaaact 18361 ctctcaacat ataccgcgcc ctcaagtgtg gacaaaagtt cacaaacatt tatcggatat 18421 ccgtgaacct ccggctttct tccaaaagga gttgtggtcg taacctgatc aatcaaggtg 18481 gtgggagcca tctgtcccga tgtcattccg taaatggcat tgtttataaa aataaccgtt 18541 attttttcgc cccttgtagc tgcatggaca atctctgccg tacctatcgc ggccaaatct 18601 ccgtccccct gataggcgaa cacaacattg tcgggattaa ccctttttgc cccggtcgca 18661 accgccggag cccttccatg ggctgcctga atcatatcac aattaaaata ctcatagttg 18721 ttgtaggcac agccaacagg tgaaacacct attgtctttc cttcaatatc aagctcatct 18781 ataacctcgg ctataagtct atgaactatc ccgtgagtac atccgggaca ataatgcatg 18841 gacacatcta ctaaagcatg tggtttctta aaaactgcat tcatttttct tccccttcca 18901 aaaataaaat cctcgctttt aaagctttaa aactttaatt gttcaaaatt tcctttatct 18961 tgtccaatat ttccttttgt gtcggtatca ttccgcccat tcttccatgg aaatacacag 19021 gttttttgcc gttgaccgcg agccttacat cctcaaccat ttggccggca ttaagttcca 19081 cagtcaaaaa tgctttcggc acatccgcat atttttcata ctcttttgtc gggaaaggcc 19141 acaaagttat aggtctgatc aaaccaactt ttattccttc cttctcggcc atcttgataa 19201 catttttcac tattcttgca accgtaccaa aagcggtcac tataatatcc gcattttcac 19261 aattgtaact ttcaacacgg gtttcccttt cctcaatcaa tctgtatttt gcctgcagct 19321 tttgattgtg cttctccaga acttcgggtt gaatatagat ggaggttatg gtattatgct 19381 ctctcttcat ctgtgtacct gttgtagccc agggcttgtc aattttttct atattctcaa 19441 catctttaaa ctcaacggct tccatcatct gtcctaaaat tccgtcaccc ataatcattg 19501 atacaattct gtatctgtcg gcaatattaa aagcctccac agtaagctca taaagttcct 19561 gaacgctgga aggtgccagt acaaccatct tgtaatctcc gtgacctcca cctttcacag 19621 cctggaaata atctccctgt gcaggcagta ttcctccaag acccggtcca catcttacga 19681 tattgacaac aacagccgga agctccgcac cggcaagata agacagtcct tcctgtttca 19741 gacttatacc cggactggat gacgaagtta agacccttgc tcccgcactg gcagcaccgt 19801 aaaccatgtt tatggcggca acctcactct ctgcctggat aaaagttccg ccaacctccg 19861 gcattttctt tgccaaataa tgtgcaattt ctgtttgtgg tgtaatcggg tatccgaaat 19921 agtgcctgca tcctgctctt aaagcagctt ctgcaatagc ttcgtttccc ttcattaaca 19981 atttttctcc catatatttc aagtccccct aatcttgttt cattaaaact ttatctttac 20041 aagttattta taaacttcta taacacaatc aggacaaata gttgcacaaa aagcacatcc 20101 aatgcatttg tccatgtcca ctactcctgc cggatgaaag cctttctggt ttaatttgtc 20161 ctcattcata acaacaattt ttttcgggca aacagttgta cacaatttac aacccttgca 20221 cctgttttca tcgaaaatta ccttagccat gtaaatcccc cattatttat tatatttgct 20281 attcttcgac caaaagctac ttcgtttatt atagaactct ttatcttttt tttcaagctc 20341 atccaacaac tcgttcagag ttttttcatt ttgaaaatca atatcgaaaa tttttacacc 20401 atactcaaat cctttttcat tactcgtttt tcttttcacg gtaccggtaa aacacagttg 20461 ttttttagga gtaataaata cttcaaaata ataatttttc tcctcctgca tattataagc 20521 cgtttccagt tctttttcga tatcttcctt ggcaataaaa gcagccccgc cctggcttag 20581 attagtcatg atggcaaaca cgcctttttc gtcatttctg tttgccttta tgactgagca 20641 caaatatata tcgtatctgt agttgtcacg tctgtttgca aatctttcga catcatgaat 20701 cttgatggta atactctgcg gttcttcaag ctttattttt gttacccagc caattaacat 20761 aaactcatac tcatcagtac tgtatttgca tctcattgta tctccaatca taattatgtt 20821 gtcaatataa tccttttcaa ggccgatatc tacctcaatc cagtcctcat taatggcata 20881 aacgacgttg gtcacccagt tggttgaatt gcaatgcttt gtcctgatta tagcgccttc 20941 tgaaagaaaa tcccgtaatt ttatcttgct cattacagtc cctccatcaa tcccatggta 21001 attttatcag accgtccagg tacaatactt cagtgttttc tatctttctt acttcatctg 21061 caatttcacg aaagccgctt acaaatgcga ttggtatgtc gagtttttga gacaattctt 21121 ttatcatcct gtgaccttca agcacatctt caacagttgt ttgaccaacg aggtttgtat 21181 tattcacaag ttttgaaact ttcagtctgg atgcactttc aatttcaaaa atcatttcct 21241 caatcttttc agcagtgtct gtcatgggcc ttttggtgtt aattacaaaa tacatttcat 21301 agtcttcgct ctcaatttcc tgcttaaatc ttgacaacgc tcttgctcca aggtcgtcac 21361 cgcccacgtc aaaaacaaca ttgtactctt ttttttcaaa caatgtatat atctccgcag 21421 gcagcgccgg aatgtcaaca tttgtattgg cataaagtga agaaatcacc cagacgcctt 21481 ttgattcaag gtgctcttta gcatcaacag ccctgaaaaa aggattaact atgtcaaaat 21541 cgacaattgc agttttaata ttccgttctc taagcttaag agcaaaattt acggccactt 21601 ccgttttgcc gctgccaaaa tgtcccgtaa aaatactgat tctttttcca aacatttcaa 21661 acacctgtaa ttataaactc ttttgcctga accttctaag taatgcaaat aaaaaacagc 21721 tattctgcaa actatttatt atactgatta taacactatt aaaaataatt tttaagtatt 21781 tttattgcaa ttttgtattg cgactctgca acctgtttca ataaaaaccg ggggtattcc 21841 cccgacatca ttatagtctt tcatataatg tttatattct atctttaaca aagcaattat 21901 tagaaattta cgtaattcag gctcctgctt tcttacagac atcgaccagc cttcttccaa 21961 gtatctttgc cctttttatg gcaaactcgt ctttatcggc cggctgctgg gcgcatacac 22021 catggtggcc gcaatcgtcg ccgacatatc cgtcgccgac aattgtcatt ccgtggacaa 22081 gcattatatc atgcagtgct ttcatagttg tttcctgacc gccaaatctt gctcccccga 22141 cagtcactcc gcatgcaaac ttattgtaga gagctttttc cgatcttaac tttctcgttt 22201 tgtcaaaaaa tgctttaagc tgtgccgaaa cacttccaaa gtatacggga cttcccatta 22261 ctattgcgtc agcttttttg aggatttcat aagcctcttc caacttcgtg cctttataac 22321 atataccgga gcaaggattg ctgcaaacaa cacaaaatgg gttctttaca gaatttaaaa 22381 gttccccaac ttcaagaacc attgtctcca ctccctggct ctttgcctct tccagtacag 22441 tattaatgag atatttcgta ttaccttcct tttttgggct tccgtttatc cccacaatta 22501 acatccctat cacctcttaa acaacaattt tagcacataa tccacaagtt ctcaagtaaa 22561 caggcataat aataaaaaaa agcggacaaa acatttatta tgataatacc ccaccatccg 22621 cttctcttac tttcataata aaatccctta tcttttcagc atctttgaaa ccgtcagtct 22681 caacaccgct gctgacatcg actccataag gttttacctt tgccactgcc gtcttgacat 22741 tttccggatt aagaccaccg gcaaggataa tcctctcatg tcctgccgcc acatccgcag 22801 ccagctgcca gtcaaacaca gccccggctc ctccatagct tccctcaaca taagcatcca 22861 aaagaaaagc atccacatca aactcagaaa taatttcaag ggattctttg ttttttaccc 22921 gaactgcctt ccatatttca attctttttt ccgttatcct gccaagaagt tccttaagct 22981 tttccacata ttccggcgtc tcgtctccat gaagctgtac acagtcaagt cctgtgtact 23041 tcacaatctc agccactgtt tctttttttt catttacaaa tatccccaca gacttaattt 23101 ggggcaaaag agcttttaca agcatccttg ctgtctcttt cgaaaccttc cggcggcttt 23161 ctgcaaatac aaaacctgca aattgaggtt tgtagagatt tacataatct atgtcttctt 23221 ttcttcttaa accgcaaatc ttaacacaag tcataaatca caccgcttta aactctctta 23281 ttttttcact tatggaccgg gcccgcataa aggtctcgcc aattaaaaca gcatccacgc 23341 caagctcttt cagatacttt aaatcttcgg tgtccttaat tccactttcg cttaccacca 23401 cccggtcatt gggtatcctg ttcataagct tttcagtatt ctttaaatcc acttcaaaag 23461 ttctaagatc cctgttgttt attccgatta ttcttgcgcc ggattccaaa gcccgctcaa 23521 gttccctttc atcatgcacc tcaaccaggc actgcatccc taaaatattt gcaacgatct 23581 ggaatttttt cagttcctca tcggaaagca gtgatacaat aagcaatatt gcatcggccc 23641 caatataccg cgactcatat atctgccaca aatcgattat aaaatccttt ctcaaaatag 23701 gaagaggaca gaactgacga atctttacaa ggtagtcttc atcccccttg aaaaagttcc 23761 tttccgtaag caccgatata gcctgaatat ccgactcaac gtattctttt gcaattttga 23821 gcggatcaaa gtcctccttt ataatccctt ttgacggtga agccttcttt acctcggcaa 23881 taatggatat atccccattg ttctttaaag ctccgtaaaa gtccagaggt ttgtggattc 23941 ccggtctttt aattttttgc ttccagcctt ctatggtaat cctgctcata tcttttttaa 24001 gctgtatttt ttttgcgcta caatttcatc cagtatcatg ttctcctcct tgtcctaacc 24061 gtgtttaatc ttttttgctt tcttaccgat aatgcctttt atcatcagcc tgacatttca 24121 ttatagctta taaatgaatt agtaaattcc acaaactcgt caagcttttg caaagctttt 24181 ccggaatcaa tcacttcttc ggcaaggccg ataccttctt caatgcttga tacaaccttt 24241 cctacatata atgccgccgc tgaatttaac acaacaatgt ctctcttagg tcctttttct 24301 ccgttaaata tccttctgat tatctgagcg ttttcctctg cattgcctcc cgtcaaatcc 24361 tcaggcgacg caagggcaat accatagttt tccgggaata attcgtaagt tataacctca 24421 ttgttccgta cctccgacac ttttgtagaa gtcgttgtcg ttatttcatc catgccgtcc 24481 attccgtgta taaccatagc cctttcaatt ccaagattca aaaggacgtt tgccataagt 24541 tccgtaagat ttggattaaa tactcccagc acctgccctt ttgcattgga agggttggtc 24601 aaagggccaa gtatattgaa tattgtcctt attcccagtt cctttctggg acccgcggcg 24661 tgtttcattg atttatggaa caccggggca tatataaatc ctattcccac cttttcgata 24721 cactctttta cctgaaccgg atcaaggtca atattgacgc ccaaagcttc caaaacatcc 24781 gcacttccgc tcttgcttga taccgatctg tttccgtgtt ttgccacata tacgcctccc 24841 gctgctgcca caaaagccgt tgctgttgat atattaaagg tgttggttcc gtctcccccg 24901 gttccgcagg tatcaatata ataatctaca ttcggacata ttttgtcagc ctttgctctc 24961 attactttcg cacaacctgt tatctcctca attgtttccc ctttgattct caacgccgtt 25021 ataaaactgc ctatctgggc aggtgttgcc ttgccctcca tgatacagtc caatgcctca 25081 attatttcgg actcacttaa atttttccct tcaaccagtt ttgaaattgc tttttttaac 25141 attttgacct ctcctctctt ctcatctcta ctattctttt aaaacaagtg cttaaaaaac 25201 ttttaagtac tgcgactcaa atcgcaactc tttttatgtt aatgaaattt tttaagattg 25261 cctttccttc cggagtaaga atcgactcgg gatgaaattg tattccaaat accggaaagc 25321 ttttatgcat caatcccatt atttctccat cctgtgttac ggcagtgatt tttaaacatt 25381 cgggaagtcc ttccttttgc actatcaaag aatgatacct tcccacccgt atcttttcag 25441 gcagatttct aaatatcaga cattccctgt caatctcaac ttccgatgct tttccatgca 25501 taagttcttt tgcatgcact acctttcctc cgaaagcttc tccaattgcc tgatgtccaa 25561 ggcatacccc cagaatgggt atatacctgc cgaactttct tatagcttct atgcatattc 25621 ctgcatcttt cggaaaaccg gggccgggag aaattattat atgcgtggga ttcatttctt 25681 ctatcttttc caaagttatt ttgtcatttc tgtagacctc aatattggga ctgatttccc 25741 cgacatactg gtacaaattg taggtaaaag aatcataatt atcaataatc aatatgtttt 25801 ctatcatctt atttcacctg cctcttctat ggctttaaga agtgccattg ctttgttgta 25861 gcactcttca tactcccttt ccgggaccga atccgcgact atgcccgctc cggcctgaac 25921 ataagccttt ccgtccttta atataattgt ccttatggtt atgcagctgt cgagattgcc 25981 gttaaagcta agatacccga tcgcaccgcc gtagggacct ctttttacgg tctcaagctc 26041 gtctattatc tccatagccc tgacctttgg cgctccggaa agggtaccgg caggaagaat 26101 ggacataagg gcgtcaaaag gagtcttatc ctcccgaatc tctccctgta cgtttgttac 26161 cacatgcatt acatgggaat atctctcaat gtgcataagg ttctttaccg ctacggtacc 26221 aaatttcgat actcttccga tatcgtttct gcccaggtcc accagcatca catgctcggc 26281 tatttctttc tcatcggaaa gaagctcttt ttccaaagcc tcatcctctt cttttgtcct 26341 gcctctcttt cgcgttcctg caatcggaca ggtttccaca attccatttt caaccctgac 26401 cagcatctcg ggggaagaac ctattattct gtagccgcca aatttaagat aatacatata 26461 tggagaagga tttataaccc ttaaggcgcg gtatatgtta aaaggatttt catttgtctc 26521 aacacacaag cgttgcgaca aaaccacctg gaatatgtct ccgtccctta tatactgctt 26581 tgccttcaac acattccggc agaaatcctc ttttgaaata ttgctggtta ccgcaagttc 26641 atttttcttt ttattgtaac ttagaacaga gttgtcagcg gttttccacc tggtgtcaag 26701 aatctccctg tgtatggttt ttatccggtc aaccgcgctt atataggccc gttcaatgtt 26761 gccgttgaca tgcaaattaa caattatatg aattttctgc tttagatggt catacaccag 26821 cacttcgtcg gtaaacatga aatggcattc cggaagaccc atgtcatctt cggggacatt 26881 gggaagattt tcatagtgtc gtatgaggtc atacccaaaa tatcccaccg ctcccccgtt 26941 gaatctcgga agattcggaa ggttggcacc tttaaacttc cccataatgc cctttattat 27001 ttcaacagga tttccttcaa cttccctttg agaaccgttc ctctccctta taatggtttt 27061 gtttttgtag ctttccacaa caagaaacgg attttttccg atgatggagt accgggccca 27121 tttttcaccg ccctcaacgc tctccaaaag gaaacagcaa ctgctttcct caaacctttt 27181 aaaaaggctt ataggggttt ccatgtcggc atatacttcc attgtgacag gtatgatatt 27241 ataatctttt gccattattt tgacttcgtc cagggttgga taaaacattc cgactcctcc 27301 ttatttctaa gaaggaagac atgagagagg accatactaa aaacgccgga tggaagaatc 27361 cggcgatatg gcgcaaatac atttattcac gctcgtctct tctcatctct tctcttcaaa 27421 ctcaaactca tctcatccaa ttcttaactt attcttatct ttaagattat tgtagcatgg 27481 aaaatacgaa aaatgcaagt taaatttcat aaatgttata aattttattt gaaacttttt 27541 caaatgatat ataataaatg atgttttgtg ccaaatatac agctttcact gacaccgtaa 27601 caataatctt tttaatgagc tgtttcgcaa taatccttga cattgaacac ttatgaaaag 27661 tacaatgtag gatgtaggat taacgcaata acttaaaaac aaccaactga caagtcataa 27721 agataaaaaa taagcaatct aaaagcaata atcaaagtac aaaggagaat cagggaaaga 27781 catgatttca aggtttatag actacatcaa aaaaaacaaa tatcttgtca taatatttat 27841 aggggtaata ctcaggctcg tatggatttt tgccatgccc acgtatcccg aaaccgactt 27901 tatgtggtat catgtaaagg gaaaggaaat tgctgaagga aaaggatttt taaacggaat 27961 ttatccctat tacaccggaa ggccgggatt tcccacagct ttcagaccca taggctatcc 28021 cgggactttg gcaatcctct atttcatatt cggtgcccac tttatagtgg caaaactgtt 28081 taatattgtg ctttccactc ttatcatgtt tttgacttac aagcttgccg acaagttttt 28141 cggtaacaaa attgctcttt tgactttgct cctttatgcc ttgtcgccct tagcaatagc 28201 atacaacagt atcatatgct cggaaattct gttttctgcg ctgttaatgt tgtctgttta 28261 tctgtttttc aataaaaaca atccccttct cattgggctt ctaattggtt atttaactct 28321 tgtaagaccc ataggagtgt ttattccgtc aatatttgta ctgtatgaat ttatccgaaa 28381 agacgtggga cttaagcata aaatcaaata tgttgcagtt tttgcagtag cagtgggatt 28441 ggtaattgct ccatggataa taagaaatta cattgttttc ggcgaaccaa tcttctccac 28501 caacggcggc tatgttttct acgtaaataa caacgactat gcaaccggtt cgtggagtga 28561 ccccttcaag taccccgaca gtccgatgct gaagtacaaa acggaagacg gatttgatga 28621 attggcaatt cacaaacttg gcaaacaact tgctagagaa tggataaaga aaaatcccaa 28681 aagattcatt gagctggcat ttctccgtat tgccaattca tactggttca aaaccgaaga 28741 tataatgtgg gcgtttacca taggcatcaa ccagtggcac cctgtaactt ctaaggctgt 28801 caagcttcaa aaacttttat accggccttt ttacatcgta cttttcatat tcattatata 28861 tgctttgata aggtttatac gacagagaaa aattgacttt accacattca tccttcttat 28921 atttctctac tttaatgcaa tgatgtttgt gctggaggga aactcaagat atgtttttcc 28981 tcttcacccg atttacacga taggcgtatc ctttgttata tacaatgtac ttaaaaagct 29041 gctgcctgaa cgtttttcag cagttttgtc ttaagtttgg tttgttgcat tgacattaca 29101 aatactatat aatattgttt cgtggattcc tcttttaatt ttaaaataag tttagcttat 29161 aacctgcaag ttgaggagat ttaccacctt gttacaaata tgcgaaagga cagatgtttg 29221 aaatgaaaat gggaatagtc ggacttccta atgttggaaa aagcactctt tttaatgcga 29281 taacaaaagc cggtgcagaa tcggcaaact atcctttttg tacgattgag ccgaatgtgg 29341 gaattgtggc cgtcccggat gaaaggctca acaagcttgc cgagatgtac aaaccggaaa 29401 aggtcacacc taccacaata gaatttgtgg atatagccgg gcttgtaaaa ggagccagca 29461 aaggcgaagg tcttggcaac aagtttttgt cccatataag agaggttgat gcaatagtcc 29521 atgtcgtccg ttgctttgaa gacagcaata tcgtgcatgt cgaaggctcg gtagaccctg 29581 ttcgcgatgt ggaaaccatt gaaatggaat taattctggc ggacatggaa gttttggaaa 29641 gaaggataga cagaacacgc aaaatgttaa agtccggaga taaaaagtat caagtggagc 29701 ttgacattta cgagcgtatc atgaaaacct ttgaagaagg caaaccggtt cgctcaatga 29761 gctttagcga ggaagagaaa aaaattgtgg accagctgtt tcttctgaca tcaaagccgg 29821 tattgtacgc agcaaacgtt tccgaagatg acataaattc cgacaaacca aatccgttgg 29881 tagaaaagct tgttaattat gcaaaaaacg aaggttcgga agtaatggtt atatgtgcaa 29941 aaatcgaaga agaaattgct cagctcgatg acgaggaaaa agcggaattc ttaaaagaac 30001 tgggactgtc ggaatctgga cttgaccggt tgataaaagc aagttacagg cttttgggcc 30061 ttatcagctt ccttaccgcc ggaccgcagg aagtcagggc atggactata gtcaagggca 30121 caaaggcgcc ccaggcggcc ggaaaaattc acagtgactt tgaaaaaggc tttatccgtg 30181 ctgaagtcgt cgcctatgat gaccttataa aggccggttc atataccatt gcgaaggaaa 30241 aaggcctggt gcgttccgaa ggaaaggact acgtgatgca ggacggcgac gttactctct 30301 ttagatttaa tgtataaaag agataaattt attttattta atttgcgttg aaaaaatctt 30361 cattctcaaa cagaataaaa gcgcatacaa actgtaacaa atgcatgcgc tttttttctg 30421 tcaaaattgt agtaactgtc cggtttattc tttgtccttt tcattctcct cggtgttttc 30481 ttccaattta tcctcattat tgttctcgct tgacccttca ttatcattgc aatcatcatt 30541 ctcattgtcg tcattcgtgt tgttttcatc ttcaaaattt tcttcaagct tgtcaatttc 30601 actgtcggtt aatataacgc tcaaatccaa aatggcaatt agcttgtcat ccttctttcc 30661 aacgcactta agatagtcat tatacacctt tttaatgatt tcaggtgttg gctctatatc 30721 atcagctgac aatctgatta tctcataaac atcatttact acaaagccaa taagcttgtc 30781 ctcaatgtcc gtaattataa tcttggtttt tttgccgact tccatgtccc ccagcttgaa 30841 ccttttattg agattaacaa ccggaaccac ttttccccta agattaataa ctccgtcaat 30901 aaatctaggc attcttggca tcttggaaac ttcttcatat ttgacaattt cttttacctg 30961 gctggtgtca actccgcaaa tctcatcatt tagactaaat acgacaatct gcataccttc 31021 catcagaaaa acctccttat tgtgaatttt ctgcatagaa ttcaatcctt cgggcaagga 31081 atatgctttt gaattggact taccataaat attcaacctt tccgatatga aatcaaaaaa 31141 ccaagaagtg aaacgctata tcttaatatt atactaaaaa agtgtaattt acaacatctt 31201 tatgaagttt tttaatcaat aaatataaag ttagcctgca tattttacat caaccgggat 31261 ttttcaacaa aattcatcat taaaactaaa ttttgtgcac aactgttgaa aatcaacagg 31321 tcggaaaact atttcaaagc atttacatca ctagaatttt gttatacatt tgtattgata 31381 ttcaaatatc aatatgctaa attaaaaaag taagaattat gaagtattgt aatatagata 31441 gacacgaatt ggtgtccata tggaaaaagt actttttaaa gtattaatcc ttctgacaat 31501 catttttttg gtggaatgtc agcagcagcc attaagttta caaaattcct ttttcaaatt 31561 tcaagaaatt tattattgac tgacatccct ttagcgtggt aaaataatta gtaacagtaa 31621 aataattgat gttaaaggca atgatggggt aaagtaggtt atatattctt tttaagcgag 31681 ccggggacgg tgcgagcccg gtaaaaggat tataactgaa gttcaccgcc tgagctgttg 31741 gctgaaaagc ggttcacacc gctaaagtag gcttaaccgg agctttcacc gttaaaagaa 31801 aggttgtatc ggattattaa taatatataa tcccgtacaa taatgagtgg gctttatgcc 31861 aatttgggtg gtaccgcgtg gagaatacac tcctcgtccc ttaaaaaata agggatgagg 31921 agttttttat ttgacttaaa aaattaaata agcaaatcca agttaaagag taaaagaatg 31981 atatatcaat attaaaatat taacggaggt tttgcctatg attatcgtta tgagtccaaa 32041 tgctacaaaa gagcagattg aaaatgtgga aaaaaaactt ttggagctgg gttttaaaac 32101 tcatcccata gtcggagacg taaaaacggt aattggggct atcggagaca aaagacttct 32161 caatacccac tccatatcca ccatgcccgg agttgaaagc attgttccaa tcatgaaacc 32221 ttacaagctg gccagcaaag aactaaagca ggaaccaacc attgttgagg taggcgatgt 32281 acgaattggt ggcaatgaag tagtggttat ggccggcccc tgtgcaattg aaaacgaaga 32341 aatttatgtc gaaacagcca aaaaggttaa agaggcagga gccaaaatac tccgcggcgg 32401 tgctttcaag ccccgtacat ctccttattc tttccaaggt ttggaagaag aaggcctcaa 32461 aataatggcc attgcccggg aagtaacggg acttaagctt gtcaccgaag ttgtggacac 32521 aagagatgtg gaacttgtcg catcttatac agacatcatc caaatcggtg caagaaacat 32581 gcaaaacttc aggctgctta aagaggtcgg aatgtccaat aagcccgtac tcctaaaaag 32641 aggactggct gcaaccattg aagaatggtt aatggccgcc gaatatatta tttccgaggg 32701 taatcccaat gtaatacttt gcgaacgagg catccgaacc ttcgagacag ccacaaggaa 32761 caccattgac atgagcgcca ttccggtaat aaaagagctg tcccatttgc cgatagtgct 32821 tgaccccagc catgcggcag gtacctggaa atatgttgag cctcttgcaa aaggcgcaat 32881 agcaaccgga gccgacggtt taatcattga agtccacagc cagcctgact gtgctctctg 32941 tgacggtcaa cagtctttga taccttcaag gttcgaacag cttatgaagg atcttgagcc 33001 tatagctctt gcagtgggaa gaaaactatt gtaaaaccgc cataaagtta aaacttccac 33061 aaatgtaata aaaccaatat aaagaccttt acaacccaaa acaacaaaat caaaaaagct 33121 cgtaagacaa aagttagatg tctttcgagc taatttattg tcttttactc ttaactttag 33181 ttttattata agctttttat attttattat acttttcact tgcttaaata agtatctgcg 33241 ttaatctgta ccgtttctgt aagtttgcct atttcatcat agcttacaac aatatttttt 33301 cctattttct ttgcataata caatgcccgg tcggcataat cgacaacctt ttttatatca 33361 tcggaatgcg tcggaaattg tgcaatcccg cagcttacag tcgccttccc catgttatgg 33421 ccttcatcgg aaaacagatt ctgtttttca agctgacacc ttattctgtc tgccacgcat 33481 ttggctttct caaggtcaag gtcccttatg agaaccataa actcttcccc accataccga 33541 aaagccatat cagtctttcg aatgctttgc tttattatgt cgccaaaaag cgaaagaagc 33601 ttatcacccc aaatgtgacc gtaagtgtcg ttaaattttt taaaatcgtc aatatcaaac 33661 ataagaacgt ttaaaggctt ttttgaatac tcacagtaaa gagcttcctc ctcgagtttc 33721 tgatccagca tatgcctgtt ggcaagccct gtaagcttat ccgtcctggc gagcttaaac 33781 tctctttggt gcatttcgtc atattttttt acttccagga taaccattga cacaccgtat 33841 gccaccaaaa gaatgaaaaa atccctgatt atgagtttta aaaagttcaa ttccccaata 33901 ttatccgctt ttaccgcaat tgacgaaacc gtgtaaagta ttatgctaaa aatactgata 33961 tttatggtac tcgaaacatc tttgccaatg ccgtaatatg aaattacaaa aaatatgaga 34021 atgtatatat ccgactcaat accgtttaat atgtaggaaa aagcacaaat aaacataata 34081 tcaaaataaa aggcaatgct tatgaatttc tttacccaac cgttcggacg cttgaataaa 34141 atgagcaaag tttgaaatcc attatacaga attgccactg aaaaggtaat ccagaaactt 34201 ttctctgtcc gcgggcaatc agaaaccaga aaaaaaagag gtatcaccaa taacagagct 34261 acccatctta agtaaacaaa atttctctgt tggcgaaagt taccagtctt ttttttcttt 34321 aaaagcccat ttattatatc attcatcgta tctcatttta ccccaaaaca atagaatatt 34381 ttaccttttc atattcaatt ttatatttgt tttgattttt tgtcaattac ttatgttgca 34441 aacctataca aacctctgcc tgattttctc ccaataaaac atcactgcca ttcccaaaag 34501 aataaggaaa gtaccaaata taagattcaa agtgattttt tcaccaagaa aaacaattgc 34561 aaacacactt gccaaaacag gctttaaaaa gaaaaccaca gaaccgctgc cggcgccggt 34621 acgaaccaag cccataaaat aaataagata agcaataccg gtgacaaaga ccgagagata 34681 taccacctga ggccatgctg aacagtcaaa tttgaaagcc ggaagacctt ttatcaataa 34741 aacagaaagc aaaattagac taccgattaa aaaggaatat gcattcattt taatgcttcc 34801 gatttttgaa gatgcccttc tgcccacgac agtatacaac ccatataaac ctgccgacat 34861 caacgcaaga aggggactta atatatttat atccctaaag gcttgtccat tgatacttat 34921 aaccgctata cccagcattc ccaaaaacat acccgcagct ttaaacaaag ttattttttc 34981 cttgtccata acggctgcaa agatagaaac aaatatcgga ttactgctga aaataaccgc 35041 cactacggct gctttagcat aagcaacgtt taaactcagc tgaagaagat tcatactgaa 35101 cactacatta aggattcccg ctgccgagac aatcatcagg ctttttctat caattttcac 35161 gtcacgcttt atcaataaga ataaaaatag cagagagccg ccgatgaaaa atctcagaaa 35221 gttgatttga aaagggtcta ctttaccaat aattgttttg cttaccacct catatgtact 35281 aaaaaaaaca acggtaacca gaataaaaag atagccaaaa ttgaatttcc tcaccgtttt 35341 tccccctcca atttaacccg tcatacttga aaaatcctaa ttcattcatt caactgcttt 35401 gctatttctt tcctaattta tcctccgcat ttgcagaatc ccatttatcg ctgcaattca 35461 taggacttcc ttactatctg tcgcctcccg atttaagcca ttatcaccat taacacataa 35521 aagatatcga ggtataatta taatataggg tggtgtaata ataatcagaa acagggtgag 35581 ttccatgata gatgttgtaa cttgtgaaat atgcggcaga ctatacaata atcccagcgg 35641 tttcttcaga gtatgtccaa cttgctatga aaatgatgaa aatgagtttc aaaaaatcaa 35701 agattatctt aacgtgcacc cttgcgccaa aatctttgac gtagtggcag accttaatat 35761 ttctataaaa caaatcaagc gataccttcg cgaaagcagg cttgaaatcc tggaaaagga 35821 taatcatttc ctgctgtgcg aaagctgcgg aaaaagtata cgcacgggca gatactgcga 35881 cgaatgctat aaaaaccgcc ataaaaatat aagagccgtt tattccggca gcagcaacat 35941 caagcattca aatgccatcc gctttagaac cgacggcaat tcaaagcgtg cttcatcaat 36001 ctagtccgtt tatgaaacat cccctatacc ctttatatat atattttttt ttatttattt 36061 attatttttg tcgaccatgg tctttttgcg ctttttatta taaacaataa aatatcacta 36121 aacatctttt tcgtaaagca ttttataaat actgtagtaa ttctccaccc ttttggtata 36181 aatctcagtt tccttgtaag gtatgacatc aagagtcttt cccgttttgc tgtacttgct 36241 gtctttcagc caggaatgca cacatgcggc accggcattg tatgatgcca ccacaagaat 36301 acggctgtca aactgctttt ccaggttgtt caaaagccag catccaaatt ttatgttcgt 36361 ctcagggtca tataaatatt ccaccttaaa attctccagc cccatcattt ccgcaatcca 36421 aagtgctgtt tcatcagtca gctgcataag accacgggcg tttttatgcg aggtcgcatt 36481 gggattgaaa ctgctttccg cctttataat tgaaaaaaca aggtacggat ctaaattata 36541 ttcagaagaa tatttgtaaa catattcctt atatttcaaa ggaaatagca ttttaacagt 36601 tccttccaga atgaatataa ttgaaatcaa tgccaccgca aaaacaaaaa acaacttgaa 36661 acttcttttt aatctgtgaa acacaaaaat acccacctta acaaatcttt tttacgaagt 36721 attataagcg cttgttgtag tgtgcttcaa caattcttcg aagctcttca caagtaccgc 36781 cgttttcaat tattacatca gccaggctgc aatagtattc atcacttaac tgggcgttta 36841 ttctttccaa cacctgttca taactaaaac cgcttctttt catcactctt tttatcctag 36901 tttccctgtc tgccactacc acccagactt cgtcaacaat atcaagaaaa ccatgtttta 36961 tcggaatggg agcatctata acaatagttt ttcccgtttt tttagaattt catgcctttc 37021 tataataatt tgagccacat gcttgtgagt tataccgttt aaaatctcaa gtttgtcttt 37081 gttattaaaa acctcaccgg caagcttttt tctgtcaatt tctccgtccg gcaaaagtat 37141 ttgggatcca aaatagtcca caatttcctg atacgcttca tgccccttta ggataacatc 37201 tcttgcaata acatcagcat caattatttg ggcacccaaa tcggccaaaa tttttgatac 37261 cgtgctcttt ccgcttccta ttccaccggt aactccaatt gtcctcaatt tcaacatccc 37321 tctatattct atattatatt gtcttgtttt atattactct ttatcttttt tattactttt 37381 ttattacttt gtctcatacc agttgctgcc cgatttaatc tccacaacca gcggcacttt 37441 cagacttacg gcattttgca tgccttcaag taaaatcttt tccacctctt ctttttcatc 37501 cttgaacgtc tctacaataa gttcatcgtg aacctgaagt atcagcctgg atttaagctt 37561 tcttttttta agctctccat gcacctttac catggcaatc ttgattatat ccgcggcact 37621 tccctgtatc ggggtgttca tcgcaacccg ttctccaaaa gaccgtatgt tgaagttgcg 37681 cgatttaagc tcaggaaggt accttcttct catgaacatg gtggttacaa aacctttttc 37741 ttttccctct tccacaatat catgcatata tttctttaca tttggatatc tgtccagata 37801 accgtctata tatgctctgg cttcctttct gcttatctta agatcctttg caagactgaa 37861 gtcccctata ccgtatacaa taccgaaatt gacagctttc gctctggacc tcatgagagg 37921 ggtaacttcc tcttttggta ttccaaagac cgatgcagcc gtggaagtat gaatgtcttc 37981 gttgtttaaa aacgcattta tcatgttttc gtcattggtt atgtgggcca gaacccgaag 38041 ctctatctgg gaatagtccg catcaagaag cagatagttt tcatccgaag gtataaaaac 38101 ttttcgtatt ttcctgccca tttcaagttt tatcggtata ttctgaagat ttggctctgt 38161 actgcttatt cttcccgtag ccgtcactgt ctggttgaaa cttgaatgaa tctttcccgt 38221 gtaaggattt ataaccgcca aaaggccttc cgcataagtg gatttcagct ttacaagctg 38281 tctgtattcc agtatttttt ccactatttc atgcctgtcg gaaagctctt ccaatacttc 38341 agcatcggtt gaatatccgg tttttgtttt cttaataatg ggaagaccca gtttctcaaa 38401 caaaataact cccagctgtt tcggagaatt gatattgaac tcttctcccg ccaaagtgta 38461 tatttctttt gttacaacat ctatcttttc ctgaagctct ttcgaaaatt ccacaagagc 38521 atcgacatta accttgaatc cgtaatactc catatccgcc aaggtccgca ccagcggaag 38581 ctcaatgtca taataaagcc tctcctggtt gttttcttta agaaggctgt caattttccg 38641 gcttactttg cttataacat gaggataaac accaacagtc tttgaaagaa cgtcaggctg 38701 catgtcctta aacaaagtaa agcttttgcc cttgcccgca agttcctcaa ccgcctttac 38761 actcaagttt aaatactcct gtgccagctc ggatatcgta taggtctcct ttgacgggtt 38821 tattatataa gctccaatca ttgtgtcaaa agccaaaccg ttaaaatcaa ttccccgatt 38881 atttaaatat actataaaat ttttcaaatc atgcccgtat ttctttatat ttccatcctc 38941 caaaacgtcc ttaaactgcc tgaaaaactc atcttcatca atattattgg taaaatccaa 39001 ataccatgct tcatcctcca cgggcgaaat tgcaatggcg gcaagctttt gagaaaagct 39061 gcccgttttg tcaatcaaat gataaataca aacttttctg gacttgagaa tattgttttt 39121 caaactctca agttcactgg cgttttttgc gattttcaca ttcagttcca cggtattttg 39181 gatttggaca tcgttcaatc caaacttgtc aataaagctt ctaaattcca gcctcttaaa 39241 tatctcatag gttttttccc tgtcaatctc cactcttttc agctcttcaa tatcacaaag 39301 ggacggcatg tttctttcaa tcagggcaag ctccctgctc agaaaagcct gctccttaaa 39361 agtttcaagc ttttccctaa gtcctttctt tttaatgctg tccaatgaat tataaaggtt 39421 ttcaagattg ttgtattctt ttatgagagc cagggccgtc ttttcgccga tacccggaac 39481 accgggaata ttgtcggaag tatctcccgc caaagccttg acgtcaacaa actgttccgg 39541 cttgattccg tagacctcca caatcttgtt gtagtcatat tcctcaacct ctgttttccc 39601 gcctctcgtc cgcggaagtt tcagccttgt ggaaggaccg atcaattgaa aagcatccct 39661 gtcccctgta accagtatta cttccagacc ctttttttcg gcgcacaagg aaacggaacc 39721 aagtatgtcg tcagcctcga acccctccat ctcaagtctt tttatattca ttgcatccaa 39781 aacttcctta agcaggggaa cctgaacccg gagctcttcc ggcattcctt tcctgtttgc 39841 cttgtaacct tcgtatttat tgtgcctgaa agtcggagcc ttaaggtcga acgcaacgca 39901 aatgtactcg ggattttcct cttcaataaa tttatgcatt atatttaaaa aaacataaat 39961 tccgttggta tatatcccgt cggatgttgt cagaagttcg ggaagcccgt aaaaagccct 40021 gttaagaata ctgtttccgt ctatggccat caatttttgc ttgctcattg cataaccctc 40081 tcaacttttt tatttaaaat accttccgtc aatatcccta agccacatgt taaatttccc 40141 gtatcaatca ttttttaaca tattctttct actcttcatt agtaggattt cgcttttttg 40201 tttctttatc cgcaatagaa ttaattgaac cgccattgtc aatgattaaa gaaacatttt 40261 cccctttcat atacattccc tcacactccc tgacgggaat gctcacctca acaccacagt 40321 catcggacac caaaacggca tagccattct caatcctttt tactaccgca tctataaaca 40381 attttaacca tcaccttttc taaattctat atttcaaaaa ttcatcaggt ttttaagtaa 40441 aaattttttc cctgttttaa tgcaaaatat aaacagtgta tgcaacaaca tacaccctaa 40501 ataattgtac acaaaaaagg gaccgcagta aacagctgtc ccttaatttt ttataatgca 40561 caaagcttaa agaaaatttt taaatttaaa gcaatttttc aacattcatt taagactgtt 40621 ggatacaaat tcggcttcat tacactccag acggtaaatc aatttatcaa gtttgtcctt 40681 gttaacttca tctatttcca caatttccaa accatattcg ttgtatatct ccctgtttac 40741 aatcctgttt atttttgcct tgaattccaa agactgaact ttgtcaaccg aagcacttac 40801 aaacacattc acaagactat ggggctggac ttcttccctg aaaaccgctc caacacccgt 40861 cagactgata tttttaatta tggcatatat cccgttatcc gatccctttg gataaaatct 40921 tgactgaaaa ttaacaaggt atcttttagc ccctctgttg ttcttcactt tgctgaccct 40981 ttttattgca acctcgacca accacggata agttatttca aactcactta ttatcccgct 41041 aacaatatat tcatactccc cctgcataac ctggcaggaa acaacatcac ctttaaacac 41101 attattcttt aagaactctt caggaattct aaaatagatg cactcgcctt cgcacttttg 41161 gatgactgac aggaccggtt caaaaatata accatgctta atgctgataa ccgctccccg 41221 tctgaaaatc tcttcctttt ccttgacaga caacacatat tcttctctct gaaccggaat 41281 ccaattagac aactcgacat tcatcattat aatccctccc tagactggtt gacgttccaa 41341 tcctttgaaa cagaaaaatt ataatgatga tatattcgac aaataagaca aaatatcctc 41401 cttaacatca agaatttttc tttttttaca caaatgctac tccttaaata ttgttatttc 41461 tactcttttt gtcttttcac tgtcatccgt cttttcatcc agggagagtt tgcttccata 41521 ttcttctttt agtttactta taaaattttc atatgtcgca gcatccatac tgaaattcag 41581 cgtattttta ttttcatcca atccggaaaa agcaacactt ttatgaccgg atttttctat 41641 ttcgacttca atctccacgt tgcacgaacg ggcaatatta ataatgttat ccgtatcttt 41701 ttcaagatcc ggtgaattta ctgtaatatt cacatcataa acagtcatgc cggttgcagc 41761 aatactgtaa gtcttctgcg gctgttctga agcaggaaca tctgaagaag aagttatttc 41821 ataaaaagat gaattttcaa tcttccgggc atcttccgat ttttcctttt ggagagaatc 41881 ttcagctccg tcataaaact tttggctttg agttgctccg ggttcttcat tgaataaaac 41941 gcttacttga gaatcttcct cgtttttcaa tccgttgtac tgaccatctt tattattttt 42001 ttgatcagat tccatcattc cgctgtattc aatacccatc gaaccaccgg tgttggtact 42061 tggaacattg ccaaacaatc cccgggttat aatcaggctt gcggcaacaa aaaccaaaac 42121 aagtccggcg gcaatggaag gtgcaaaacc aataaacttt ttcctgaaag acaaaatttt 42181 gctctctgat tcatttttct tcttttccgc cacaagtttc tcgtgaagct gctctttaaa 42241 tcctgaagga agctcaacct cctcaacttc tcccaacaca tccacaattt ctttcaattc 42301 gtaaagctca cttctacagc tttcacaagt ttctatatgc tcttcaaact cccttttagt 42361 ttcactgtcc agttcaccat ctatatataa agacatcaat tcgattattt cgccacagtt 42421 tttcatctcc aaccctcctt tcaatattat ttgacgtatt cctcatttat aagttccttt 42481 ttttgttgaa gtattttttt cagagcctgc cgtgccctgt tgattctcga cttgaccgta 42541 ccttccggac attttataat gttggctatc tcttcatagg taaagccctg aatatctctt 42601 aatactataa ctgtcctgta ctcttcaggc aacatgttta ttgaatccat tacagctctt 42661 ttcagctcat tatcctcagc cttaagttca ggtcccggtg aatcgtcctt aatctgacgt 42721 tttatttcat tcccacctaa ttcaatgtct tcatccaaat atacaacctt cttgttcttt 42781 cttttacgaa tctcatcgag gcaggcattt gttgtaacct tgtatatcca tgtattaaaa 42841 agagaatcac ctttaaaatt ttttatcgat ttatatgcct tcaaaaaaac ttcctgcgcc 42901 aattcactgg catcatcata atttcccagc attctcagcg caatgttgaa cactttcttc 42961 tgacatcctt ctataagctg ctcaaaagct tcaacatcgc ctttttttgc ccttttaatc 43021 aattcctttt ccgaactgct catgctacca gcctcacctc cggccctaaa atgatataaa 43081 accaaccact gcaaaaataa aaaaatcatt tgctttacct ttaggttttt attatacaat 43141 ttttttaaaa taatttaaac cggtacagtt ttttttcata caaaagtaat attattcact 43201 ctcatatatt accaaaggtt ttttttataa tttatagaat atacttatca ttagattaaa 43261 ctaaatttaa aaggggtagt actatgatta atacaatttt agtaattgat gacaatgtct 43321 ttgacaatgc catcatcaaa aattatctct ccggtgaaag atacagcata atttccgccg 43381 taaacggccg tgaagctttg gaacttattg aaagccgcaa tatcgacctg atacttcttg 43441 atatagtcat gcccataatg gacggatacg actttttgaa agaattctca aaaacacctt 43501 attacaagga aattcccgta attgtcgcat caaatcttga caatgcggaa aatatagaaa 43561 aaatttttga atttgagata tttgattata tcataaaacc gttggaccaa attaacaaat 43621 tgatattttt aaacaaaata aaatcagcct taaaatacag aaatgctctt tcagagctta 43681 acaaagccac aaggcttatt aaccagctgt cagccaaaga ggcttgaact cactttatat 43741 tttgctcaat attttacgca agcaaaaaca ccagccatgt aagctggtgt ttttgataat 43801 ttacaatatt gagtaagcct gtaagccggg ttctgtcttg gatagtcatc tatctaggct 43861 atatatttct atatagctca agccacctac ccgggactgg cgggccacct taacgtccct 43921 ctatgcggtg ttgctccggg tggggtttac atagccggta agtcgccata ccgctggtga 43981 gctcttacct cacctttcca cccttaccat gctgaaaacc gaaagcactc gacctcaatc 44041 ttcagcaggc ggtatatttc tgttgcactt tccttgaagt cgccttcacc gggagttacc 44101 cggcaccctg ccctgcggag cccggacttt cctcgtgtac ggcctttcgg cactgtaccc 44161 gcgactatcc ggcttactca atattttcgt ttttatcggt aaaatatatt atacgcatac 44221 aaaatattaa tgtcaataaa atttaaatgg gtcttcttcc atattgcttt ttataacctc 44281 aacttctgga aaattctctt ttatcagttg tgcaagcctg tcggcaataa tcctttccgt 44341 attaaaatgt ccggcatcta taacacacat tcctatttcc aacatatcta cggcatcgtg 44401 atattttacg tctccggtga ccaatacatc cgcttttgat tttgcagctt ccattacatc 44461 cctgtcgaaa cttccgcaga atacggccac tttttcaatt tctttgttag tttcgccaat 44521 tactcttacg ttttttacgc caagcttttc ttttacaact gctataaact catcaaggct 44581 cttaggtttg tcaagcactc ccacatttcc catgccatac tgcctgcctt ttatttcaag 44641 aggataaacg tcataagcca cttcctcata aggatgaacc tttatcatgg cctctataac 44701 ctttttaagg ttcctttgac ttaccaccgt ttcaatcctg tattcatcaa ccttctccaa 44761 gttgcctgtt gtgcctatat aagggtttgt cccctccaaa ggcctgaatg ttcctgttcc 44821 cgccgtcata aaggagcagt cgctgtaatt gcctatccat ccggctccgg cccggctcat 44881 tgcatctctg accgcatcca cgctctcatg aggtacaaat acaacaacct tgtaaagttt 44941 ttcagccttg taatctttga gactaattat atccttaagc cccaaaatcg aggaaagata 45001 attgttaact cctccatggg caacatccag attggtatgg gcactgtaca ccccgatatt 45061 gtttcttatc aatttgtaaa tgatattccc ctttggatcg tcctcattta ttcttttaag 45121 gcctttaaat ataacaggat gatgggaaac aatcaaatca gctttttttg ccacagcctc 45181 atccacagtt ttcgaagtca catcgagaca cacaaaaatt ctttcaacag tactctcccg 45241 gcttccaatc agcaatccga cattgtcata atcctccgca agactgacag gggccagttc 45301 ttccatgtat tttattatgt cctttgcttt aatactcata aaatcactcc tctcaagctt 45361 tttcctggta ttccgtaaaa agccttgata tttcatttct tattcttatg gtatccaatc 45421 gttttttaga gtttttatcg ttcatttttt ccatttccaa aataatttta tccatctgtc 45481 caatcttctt tttaatgagt tcaggcaaaa gaggatcttt gttttcaaaa agtttctcgc 45541 cgatataata atacacttcg tcttttattt ttacttctcc cgtccacttt acagccatgg 45601 cagtatatat tctgtcttct tcctcttttg caagtctttc gtcaaaaatg tcaaaaccgt 45661 tttcacaaag ccaccggcgt acaagttcta ttgcattcat cggctggatt atcagcgcat 45721 ttgctctttt tgcctttcca aaaccttttt ccaatatttc ttttataagc agtcctccca 45781 ttcctgcgat aactacaaca tcaacctcgt tatcctccaa aggctccaat ccgtacccta 45841 ttctggtgct tatgtattgc gaaagaccat attcagctat atttttctct gcaaaaccta 45901 tcggcccttt tctcacatca caggccaacg ccctttgaca ttttttattc atcacaagat 45961 aaatgggaat atatgcatga tccgtcccta tatcgcatac aatattgcat tttggggtta 46021 ggtcggcaat aagtttcaaa cgccctttta attccatgac ggctcccttc aaaataaaaa 46081 gtttgacact atacggtaac aattatatta gattttttgc acataataaa tagtataaaa 46141 acatttttaa atttttataa aggagatgtt tcaatgatac aaagccacag actcgtcgca 46201 aaggatacgg aaaaaccttt cgagacggaa atcaccggca tcacagagcc tttatatcaa 46261 gttatcagca aaaaaagcac ccctgcctta agtcatagag agttaaatga aaactttgac 46321 acctttttgg agacaaaaaa ataaaatcag gagtatttca tacttcctga ttttattccc 46381 tatggtgggc cttcagggac tcgaaccccg gaccaaccgg ttatgagccg gttgctctaa 46441 ccaactgagc taaaggcccg tctggctcct caagtaggac tcgaacctac gaccctgcgg 46501 ttaacagccg catgctctac cgactgagct attgaggaac gttttgtgtc agcaactatt 46561 tgctaaacac aaaatatatt atacttatgc acttctccaa ggtcaagaat tgttttttcg 46621 tcattacaac aatttataat cacttttctt ttatttttag cctattactt tcattttcat 46681 ggtataatac tttagttttt gtttttatat tcgagtaaaa gttccctgag ttccgccgca 46741 tgcctcccct catcctcggc atatctttta aaaatttcct tgattttttg atcttctatt 46801 cttttagaat acatttcgta atctcttacc aactccattg aattttccca tgctctaagc 46861 aacctgtcgt aagttgtaat ctctatttca tttctgttca tatcttccat atcatccact 46921 ccatcgcata atttatttta tatcattcat atgttgcttc aagcaatgct tttttattca 46981 atcgcattga aatcatttta aaataaggat tttaaaattt attttaaaaa tcccttgatt 47041 tttattttta tatctattaa tatactacta gtatagtaat tatactcccc tagttcctgc 47101 aaatatgcgt agagcaaatt tgcaggatgt tttttattat cttcaatcta aaacgccaaa 47161 ctaaaagagc caggcagcaa atcccggctc ttaaaatcaa tccaaataat ccttcagttt 47221 tttgctcctg ctcggatgtc taagtttcct aagcgctttt gcctcgatct gacgaattct 47281 ttcccttgtc acattaaact cttttccaac ttcttcaagg gttctggccc gtccgtcatc 47341 cagcccgaat cgaagcctta aaactttctc ttctctggga gtcaaagtat ccaaaacgtc 47401 tacaagctgt tctttcaaaa gcgtaaaagc agcagcctct gacggtgcag gagcgtcatc 47461 gtcaggtata aagtccccaa ggtggctgtc ttcttcttca cctataggtg tttcaagcga 47521 cacaggctcc tgggatattt tcattatctc ccttaccttt tcaacaggca tattcatctc 47581 cttggcaatc tcttcaggat gaggttccct tccaagctcc tgaagaagct gcctggaaac 47641 tcttataagc ttgttgatgg tttcaaccat gtgaacaggt attctaatgg ttcttgcctg 47701 gtctgcaatc gctcttgtaa ttgcctgtct aatccaccat gtggcataag tactgaattt 47761 gaaacctttt ctgtaatcaa acttttccac cgcttttata agcccgagat ttccttcctg 47821 aatcaaatca agaaaaagca tgccccttcc gacatacctc ttggctatac ttacaaccag 47881 cctcaggttc gcctcagcca gtcttctttt ggcttcggca tcaccctgct ccatcctgtg 47941 agccagctct atctcttctt ctgcagtcaa aagaggtact ttgccgatct cttttaaata 48001 cattctgaca ggatcatcta tacttatacc ttcgggaatg gaaagatcca gatcatcttc 48061 cgtaagctgg atatcctcca tttccgcttc gatatctcct actacatcta ttcccatgtt 48121 ttctaatgtc tcataaattt tttcgatctg ttccggatcg atatcaactt cttcaaaagc 48181 atccataatt tcctggtatg tcagcattcc tttttgtttg cctttttcaa taagctcaag 48241 caaaattgct tttttatcgc tattgggttt cacttactgc ccctccgttc attaagatgt 48301 atctctctac atacttttca ttctatatac ttttcatttt caataatact tcctttaact 48361 ccaacttcag cttttccgaa tcttccgttg acaaatttcc ggaagaaagc tgttggagta 48421 tctctttttg tctatcctcg agccggtata attccatttt tttaattata tccataactg 48481 cctttatgtt atcatcaaaa ttacattccc cctgtatcaa tcttgcaaat acgcccgaag 48541 tctcttcgcc ggccaaattt ataagctcgg caggaacaat tcccttcttc tcttcgaagc 48601 gtttaaaaac aatctttgct atttctttgt tttgttcatc tttaaattca tcaacaatta 48661 tcttatcttt tacaacttta tataaagaat tatcaatgct aagaagacac aataacatcc 48721 tttcacactc aataatcttg tcataactgc tttttttgcc gtttttctca atcttaagtc 48781 ggttattgtc gttttttgcc gtcaaagtcc tcgttaaagg tttatatacc gtttttggct 48841 ttatcctttt cagtatttcc gcatatatcg actcctggct tatatcatac tcctttgaaa 48901 ttttcttaat atacatttct ctttccatgt tattatcaat ctttgacagc aaatccgccg 48961 ccttattaag aaaattaatt tttccctcag tagtatttgt atctatggtg gattttaaag 49021 cctttatttt atactcaact aaagaaagcg cattttccac cagcttgtta aaagcctcag 49081 ggccgttctt tttaacaaat tcatccggat cttttccttc cggtattata aggaccttta 49141 cattgcatcc tatatcattg agcaaatcaa gtcctctcat tgttgcagcc attcctgcgg 49201 tatccgcatc gtaggatata attatctctt ctgcatattt ttttaatatc cttccctgac 49261 tttcagtcaa agccgtgcca agagatgcca cagtatttat tattccaaac tgaaacaagg 49321 atattacatc catatatcct tcgacaacta ttattctttt ttgtcctgaa ttcttggcaa 49381 agtttaaacc gtacaaattt ttccttttat tgtaaaccaa cgtttccggg gagttcatat 49441 actttggagt agaattatcc aggactcttc caccaaaacc aattacattt ccccttaaat 49501 caaatattgg aaatataatt ctacctctga acctgtcata ataaccgccg ttttttcctt 49561 ttaaaatcag tccgctgtct aaaagtattt catcatcata accttttttc cttaaatgat 49621 tgtatagcgc gtcccattct tccggcgaat agcctaaacc aaattttctg gctatgcttc 49681 cgctgacctt cctttttgtc aaatactctc ttggcgccaa attcttttta tcattcagct 49741 gctcatagaa aaaacgggcc gcttcaacat taattctaag aagttcctgc ttttttcggg 49801 caataatcct ttcttctcgt tgtctccctc gggaagctgt atccttgccc tttccgccaa 49861 catcttgact gcctcaatgt agtcaaggtt ctccacttcc ataacaaact gtatgacgct 49921 cccgcccttg ccacatccaa aacaataata cagctgcttg ttcgggtcta cactgaatga 49981 aggggttttc tcactgtgaa atggacacag tccgaaataa ttcttgcctt ttctctccag 50041 tttgacgtac tcccccacaa cacttaaaat atcattgctc attctaattt cttcaatcaa 50101 ttcttccgga taatatttat acattctcta ttcttctttc cccaaacaac tcctttgtaa 50161 aaactttgtt atttgataaa catgctgtct gccacagttt aactatattc ttcgacatat 50221 ttgtttatat tccttctttt tttgttaatt aacatactta aattaatttc taataagtta 50281 caccccgtta ttgctgtaac aaaacaaaat aaaagaccag catgatatga ttttatttta 50341 ttcttcataa aaataaattt tccttcttta aataaaaaca aatattttta gatattcttt 50401 ctactttact gccaatttat acgtttaaca taaattcaac ataaattcaa cctcaaacac 50461 aaactattta acttttttat attcagtgcc acgattccgg aataaatatt tcgtgaaatt 50521 tttttaccgc atatctatcg gtcattccgg caatataatc acaaacaacc ctgtctatat 50581 ccgaatgttg aagcattttc gccgcttcct ccgaaagaaa ttccggcctc tttttaaggt 50641 agttgtaaag ctcttttatt atgttttggg ctttcatttc gtgctttttc gcttttgaac 50701 ctatatatac attgtcaaac ataaattctc tcagttcgtc cattgcttcc tgaaattcac 50761 tgctcatctt tatcgtgttc ctgtctttgc tgttggctat aatatctaca atcatattgt 50821 ttatccttct tccggaagta ttacccaata ctttgacaca ttctttggga agactgtctt 50881 ctgaaataat tcctcctctg atagcatcat ctatatcatg atttatatat gctattctgt 50941 cggcatatct tataatctgt ccttccaacg ttgagggaat ggtgtttcct gtgtgattga 51001 gtattccgtc tcttacctcc catgtaaggt ttaacccatt gtctttttcc aatacatcca 51061 caaccctgag actttgctcg ttatgcttaa acccatgggg acatatctca tttaatactc 51121 tctcaccggc gtgcccaaag ggagtatgtc ccaaatcgtg tcccaaagct attgcctcag 51181 tcaaatcctc atttaatctt aggcttttgg caatagtcct cgctatctgc gaaacttcaa 51241 gagtatgggt aagcctcgtc ctgtaatgat ccccttcggg agaaagaaaa acctgagtct 51301 tgtgctttaa tcttcgaaaa gcttttgaat acaatattct gtccctatcc ctttgaaacc 51361 gggttcttat atcacattct ttttcctctc gcagcctgcc gcgggaatca gcactttttg 51421 ccgcataagg tgacaatatt tgagcctcaa gcttttccag ttcttcacgt atgagcaccg 51481 aacacaacac ctccctgcaa ataaaaaaac ctgtattttg tatttatatt atacaaaatt 51541 cacaggtttc cttccaaaaa tcattatatt tctgcttgta taacttttct taataatata 51601 taaatatata ttgccaataa atgattataa tatttcaagt atttttaaat ctttttccac 51661 cgtaagatca atgtactggt catccactct tataatcggt cttgacacat atcttggatt 51721 tatatataca atttcacata tctcaccggt attaagcttg gcaaaatctc caatatagta 51781 tgcggctata ttgctgagaa aagcattaac cacccttaca tcaagctttc ctaccgcttc 51841 ttcctctatt atgtgaaata cttcaaaagg actttctttc tctctgtaca ccctgtttga 51901 cgtcatggca tcatatatat ccgctactgc tatcaccctt gccatcatat ttatttgatc 51961 acttttggcg cctgtaggat aaccgctgcc gtccattctc tcatggtgca taagaacggc 52021 aatggccaca tcccggtcga tttcatgctc cttttcaagt atcctgtagc cgtaaacagt 52081 gtgtttcttt atctcctcat attcctccgg agtcagtttt gaaggcttgt tcaaaatttc 52141 tttcggtact ttggccttgc ctatgtcatg aagcagacct gcctgaacaa gctttataag 52201 gctgtctttg ctgtaaccca gccactttcc caacaacatg caaagaagag atacatttac 52261 acaatgggtg taagtatact gatccgcact ttttatttga tttatacatc ttactatatc 52321 ccttttttcg tccaatcttg cgaccacaga cataacaact ttgtcaacct tttccatgtt 52381 gatattttta ccgacagccg catcataaag aatgcttttg aaacaattga cactagcatt 52441 gtatgaaaca ttaaagctct cggaaatttc agaagaaaca aaattcttat ccttttcgat 52501 taccctgacc ttggtgtaat ttaagttaac aagcttcttt atcatatgat cgtccaatat 52561 tgttccttcc gaaatcacta ccgagccata atcattcatt atggtttcgg caattctcat 52621 gccaggtttt acttcttcca gcggtaaaaa tatttttgac acattattcc cccaattctg 52681 aatcggtttg taattctgat tttgtctata ttatttctat attattatcg tatttttcct 52741 ttatatagtt tataaataat tgtaattcga cgtttcgatg gtaaactttt tgcattgatg 52801 atgtatgtat tttatgttaa catttatgaa gtgcagtgat attcttcact attttttatc 52861 ttttttataa ttgttgttgt tttatgtcaa tacacaaaaa ggtatgattt aaacggaact 52921 tcattttaat tgaatatttt ctgtaaatat tttttgagaa ctgcctcaaa ccatacaata 52981 attctctcaa gggatattta tatttatatt aattatgtgg aaggggtgct tataaggcat 53041 gcagttaaat aatatgaaaa aaatagaaag aatagcaaaa caatttaata aaataaaccg 53101 tctttcaaaa attatcataa aatacggttt ttttaccttc tttgcgctgt ttttactcgg 53161 agcgttgaca attcttatgt atcaaacggt gttttactca aatagctata tttattattt 53221 aggcacgcaa attgtaaaaa ccagttttac catacttgcg gaagtaataa tcggtggcct 53281 cgttatcgat tttattgcag aaaaaggtta agaactgaac aatccaaaaa ggattcccca 53341 attcttaacc ttcatatttc cccatgcttc tcttcgcttt taatattaat tattttattc 53401 ttttcatcca cgaaaactac tttcggatta aaagttttag cttcttccct gtcaaatatt 53461 ccataggaaa ttataattat caaatccccc ggatgaacaa gccttgcggc cgctccgtta 53521 aggcaaatca ttccgctgcc tctttctcct ttaatgacat aagtttcaaa cctgtttccg 53581 ttgttattgt caaccacttg aaccttctca ttttccatta tatcagcagc ttccattaaa 53641 tcttcatcaa tcgtaatgct gcccacatag tccaagttcg cttcggtcac cgtggcccta 53701 tggatcttgg atttcatcaa tgttataaac atactcccta cacctccaca attacattgt 53761 caataagtct cgtacttccg aacttgacgg ctaatgccac aagaactctt ccttttatct 53821 catcaacatt ttccaaagtg tcggcattta ccacttcaac ataatcaatc actgcatttt 53881 tctctgtttg tattctgtca attatatatt ttctgatttt ttttgcatcg gtttcgcctt 53941 tttttataag ctcctcggcc tccattaagg attttgaaag tatcaccgca gattttcttt 54001 cctccgggct taaatacacg tttctcgagc tcatggcaag tccgtcttct tcccttacta 54061 taggacaggt tatgatttca acgttcatat taagatcttt taccattttc tttattaccg 54121 caacctgctg ggcgtctttc tgcccaaaat atgccctgtg gggttcaaca atattaaaga 54181 gtttggttac aatcgtcgta acacctctaa aatgtcccgg ccttgattta ccacagagaa 54241 cttcagttat accttcgaca tttacataag tcttgtatcc gtcgggatac atttctttaa 54301 ccgacggtgc aaaaaccaca tcaactcccg ctgcctccgc aagcttcaaa tctctctcca 54361 aatccctcgg gtatctgtca aaatcctcat taggcccaaa ctgcgtcgga tttacaaaaa 54421 tactcatcac ggtatagtca ttattctgcc gcgacatatt taccaaagac aaatgtcctt 54481 cgtgcaagta tcccattgtg ggcaccaaac caattaccct gcccagattc ttttgtgtcc 54541 ttatgatggc ttttaaatca ctgattgtct ctattactct cataatatat atactccctt 54601 gtttgttttt gtatccaata gttcaatatt aatattataa tccctaaatg tcaaacctaa 54661 ctttatcaag ctcatcaata atccaatcat ccactttaaa agaatttttt tctgttggaa 54721 atactccgtt tttcacttcg tctatatagc tttttaccgc cgtggataca gtttctccaa 54781 tctcagcgta ctttttaaca tgctttggag taaaatcctt aaacatacct gtcaaatcat 54841 gtatgacaag aacctgtccg tcacagtccg gaccggaccc aattcctatt gtgggtatat 54901 ccaatctctt tgaaataaaa gccgcaagtt tatacggcac acactccaaa accacggcaa 54961 aaacccctgc tttttgcaac aaaagtgcat cccggtatat tttctttgct gtgtcaatag 55021 tttttccctg agccttgtgt cctccgaaaa catttattga ctggggtgta tatccaagat 55081 gtccgactac gggtattccg gcactgatga tggccttcac gttttcaatt atatcctcgc 55141 cgccttcaag ttttacagcc ttgcagcccc cttcggacac aagtcttccg gcatttctta 55201 cactgtcgtt ttttcctgta tggtaggata aaaacggcat gtctgcaaca accattgccc 55261 tttttactcc ccgcacaaca gcttttgtgt gatgaaccat gtcatccatc gtcacccgcg 55321 tagtatcctc atatcccagg actaccattc caagagaatc cccgaccagt attgagtcca 55381 ctcctgcttc atccaaaatt ttagccgttg ggtagtcata ggctgtaagc attgtaattt 55441 ttctaccttg tttttttgat tccaaaaagc ttgccgttgt aaatttgtcg ttcataatca 55501 taccttcttc cgtcttggat tccaaaatca aaaaagtcaa tccgacagga ttgactgata 55561 tttgacaata aggccgcaaa ctatattttt gattcatcac cctgtctctg tccgctttcc 55621 ggatcaaagc agaaaatatt caaaaaacat tttttcaaca ttttataaat taatattata 55681 aattaatatc cgcagtgtgg ttcaaattga taccacctga gtatagttaa atattaacac 55741 agtcacggcg ataaatcaat aattacgaaa gaaaaattaa aataaataaa aattggacag 55801 aagccttaac ttccatccaa tttgtttact aataaaaatc atctaattat caaaagcagt 55861 aaaatccact taagcctttg cagcctgtga agcctttctc tttgcctgct tttccttaag 55921 caattcccaa agcggacttg caataaatat tgaagaataa gttccgcaaa taagaccgat 55981 tatcaatggg aaagtaaatt ctttcatcga accgattccg ttatatgctg caaatgcata 56041 aaccgttatt acggatatta acgtggtcac actggtattt atcgtccttg acatggactg 56101 cgtaatactg ttgtttacaa tggttcttat ggaatctttt ctggaaatcc tgctgttttc 56161 ccttattctg tcatatatta ctatggtatc attaaccgag tatcccagta tggtcaatac 56221 agctgctata aaagactcat taacaggtat gttgaacacc gcatataccg caaccatcat 56281 caaaacatcg tgcaataccg ccacaacggc agtaaatccc gccaaaagtc ctgacatgat 56341 attaaaccta attccaatat ataaaatcag caatatcaaa gacaaggcaa ccgcaagcaa 56401 acctttggta agcagttcgg ctcctattga agggtcaaca tccctcactc tcatttcacc 56461 gttttctttt acgttgaatt cagctttcaa cgcatcaaga actttgttgc gttcatcatc 56521 ggtaagcttg ccgctcgact ttataacaag aaaactgata gcttcatcgc tgtttgttgg 56581 attgaaggta tatgactttt gtacgtgaat accgctttta ccgatagctt cttttgctat 56641 attctcagct ttgatgacat caaaatcccc attttccatc tctatttcta tttgagttcc 56701 acctctaaat tgtatgtcaa gattaagtcc tccacggact atcaacgcaa ccagaccaat 56761 tagcaacaac acagtggata gtatgaaaaa atattttctc ttgccgacat aatcaaaatt 56821 aaacatttgc agtacctcct ttagccccaa aaagccacgg ttttcttaaa acacgtattt 56881 gtgacaatgc gttcaacaca atttttgttg caactatggc agtaataaag ttgacaatta 56941 tacctagtcc aagggtaatg gcaaaggatc taaccgctcc tgttccaaag taataaagaa 57001 ccgcagcagt tatcaatgtg gtcaagttac cgtcaagtat agcggtaaat gctctcttaa 57061 agcccaattc aatggcagct tgaactgttt tgccgctcct gagctcttcc ttgattcttt 57121 caaatataat tacattggca tcaacgctca tacccacagt aagaatcaaa cctgctatac 57181 cgggaagagt gagggacatg ccgcttaaaa caaatactaa tataatagcc gcaacctgtc 57241 caagaagtgt aatatctgca accaatcccg gaactctgta ataaagcagc ataaacagcc 57301 ataccagaat aattgcaacc gctccggcat atatacttat attaagcgca ctctcaccga 57361 taatcgggct gatgtggttc acatcctttg cctcaagctt gaaaggcagg gcaccggatc 57421 tgattatggc agcaagttct tttgcatatt caattgattc atttctgtcg atgaacccaa 57481 gattgattac cgctctatcc tttccgctta ttttttcgtt aactatggga gctgaaatca 57541 tctggtcgtc aagatatatg gcaattcttt tccctaccag tctttcggtt gcctcttcaa 57601 actttttggc tccctcatca ctgaatatca accttacaat accatattgg gtttgagggt 57661 ccgtctcagc cacggcactt tctatgtcat taccctgaag tactatcctg tcggtcattt 57721 cataaacccc ggtttcaggg tccaccttat cctcgtcaac ttctctgaaa gtcagcattg 57781 ccgtagcacc aatatcggca attgtttcat agggatcgcc atattcaccg ccttttttgt 57841 aaggtatttc aacaagtacc cttttgttaa ccctgtccac cgttacagtc ttgtcataaa 57901 tctgctttcc ttcaagtctt gtatcaatta tgccttttac agtatccagt tcgtcatcag 57961 ttggcgttat cccatccgga gccgtaagaa cagcacttac tccaccgctt atatcaattc 58021 cgtatcggat accgtcatac gccttgggta taacaaaatc cgtattcgga atttttaatc 58081 cagtaaaaac aattgcggtc atcgctgcaa taactgccaa aaccaagaag aatttaatcc 58141 cgctgctcca tctcatttgt aaaattcccc cttttaaatc ttttcacatg tggttattat 58201 ataacttcag taaaatcgag tcaatatact atttttctca acaaaatttc ataattcaag 58261 attagacaat ttatattgta taacaccaaa ttttacctcc gaagcaaaaa aacaaaattt 58321 aaaggagatg ggttccgtta attataagct tgaatttaag tcccaaatac tccgcagccc 58381 ttctgttcat ggtcattcgg accaaaaata tttcaaaata atccattacc ggacagattt 58441 ttgtatctat ctgaagttcc agaaccacca gctttttttc cttgtccaca tacaattcag 58501 agctttcaac agcatagttc accctgtcat gaatgtcaaa ggtcgccatg tcattgttcc 58561 ttacgcgggt tctgtgaaca tcggacttgt ccgcaagaat aagagctgca gaaatattgc 58621 taacaggcgc tcccgtattc tcgtcgtgat ttccgatagc cagcattatc tccgccgctt 58681 cgctgtagct catacccatt ttggtcaaaa tattataagc cagtattgcc cccgaatggg 58741 catgatccac cctgttcact gcgtttccga tatcatggag atagcctgca attttggcaa 58801 gctcaacttc ccgttcagga aatcccagag tcttaagtat ttctcccgct tcttttgcaa 58861 ccaatccgac atgtctgaag gaatgctcgg tatatcccaa tgctgcaagc tgcctgtccg 58921 ccacttcaaa aagcgccctg atttcttcat tgtttttcaa atcttccaat gatataaggc 58981 ccatataaaa cctccccaca aaaaaaattt ttcattacat ctcctgtgcc tttatccaca 59041 atgcgcattc aactcttttt ttctccaatt cgcatccgac tttgtacaca gtattgatat 59101 ctttatgaaa attatacgaa ttggcggcac atcctccgct gcaataaaac tttgcccagc 59161 agctgtcgca ttctttcttt gtatatacat tggagttttt gaaatagttt tgaatgtccc 59221 tgttcaaaac tccttctttg acattaccca ttttaaactt ttcatttcct acaaattgat 59281 ggcaggggta aatgtctcct tcgggagtaa ccgcaagata ctcatgtccc gagccgcaac 59341 cggtcaatct tttgacaatg caggggcctt gagtcaggtc aatcataaaa tggaagaaat 59401 taaaccaatt tccctctttt cttcttttca catactcata tgccagcttc tcatattctt 59461 caaaaagcct tggaagatct tcctccctca aatcatatcc gctgtccttt gccgcaacca 59521 caggctccac cgaaatctgc ctgaagcctt catcggccag atgcagcaca tcattggaaa 59581 aatccatatt ttccctggta aaggttcctc taacatagta attatcctga tttctggact 59641 ctgcgacata tttaaacttc ggcagtatat catcataaca gccgctgccg tcaattctta 59701 ttcgcatcct gtcgtttact tccttgcgcc cgtcgatgct cagcacaata ttttgcatat 59761 tttcatttat atactttata ttttcatcat tcaaaagcag tccgtttgtc gtcaatgtaa 59821 atctgaaatt tttattgtgt tctttttcct tttgacgggc gtattcaata atccccttta 59881 ccacgtcaaa gttcatcatt ggctctccgc caaagaaatc tatttccaga ttcttccgat 59941 ttcccgattc tgaaatcaaa aagtcaatgg cttttttgcc aacttccagg ctcatcatgt 60001 ttctctgtcc gccgaaattt ccggtggatg caaaacagta tttacatctt aaattgcagt 60061 catgggatat atgaagacac agcgccttta ccaccgactt tctgtccatg gaagaaacat 60121 actctttgta agggtcttcg gaaaaaagca gcccttccgc ttcgagactt tcaatttccc 60181 tcagtgcttc atcgatttca tctgcattgt acttgtgagc aagtttgttt ttaatctccc 60241 cagcagtaaa gtttttataa taatccagta tgtcgaagga tatgtcatcc accacatgga 60301 cggcgccgct gttgacatcc acaactatgt tggttcccat cattgaaaac ttgtgaatca 60361 ttgccatctt aacttaccac cttgttcttt aaccattcct taaaataaaa aaataacgct 60421 aaaaaagtga aaagcgaaat acttgtttca cttttcactt tgtcaattgt aatgaagaca 60481 gatgcttatt gttttctacc ccttttatgt aaaaggatta ccttttttca cagctttggt 60541 tcgctacggt gcaggaagtc ttgcaagctg actggcaaga agtctggcac tcgccgcatc 60601 cacctttttt caagctgtct tttaatgttg atccgtttaa aatcttaata tgcttcattt 60661 gctttccccc tatagtaaaa tttacacgtt gtattatagc acaaatagtt ggcgttgaaa 60721 agaatattat aaaatcaaaa ctctttttta acttcttaac tttttctcaa cttttcaaga 60781 agctctttaa aatactcggg aagcggtgac tcaaactcca tatactctcc ctttatcgga 60841 tggacaaatc caagcttctt tgcatgaaga gcctgtccgt ttatgttgta tatatcattt 60901 ttccttccat aaaccgtatc cccgataatg gggaagccta tgtaggacat atgaacacgt 60961 atctgatgtg ttcttccggt ttccaaagtc gcctcaatat aagtggcatc cttgaatctt 61021 tcaagcactt taaaacgggt cactgcccgc ctgccgtttt tggtgttcac agccatcttt 61081 tttctgtcaa cagggtgcct tcctatggga gcgtcaattt tgccataatc ctcccggatt 61141 atgccatgaa ccacagcaat ataaactctt tcaatgtcat gatccttaag tttttcagac 61201 aaaccttcat gcgcggcatt gctctttgca accaccaaaa ctcccgaagt atccttgtca 61261 attctatgga caataccggg tcttataatc ccgtttatat tggaaagatt ggtgccgcaa 61321 tgtttaagca gggcatttac caaagtgccg gaatagtttc ccgcagccgg atgcactacc 61381 atgcccttgg gcttgtccac cactataatg tgctcatcct cgtacaatat gggcacatca 61441 atatcctccg ccaccacatc aagaacttga ggctccggta ttcttgccag tatctcgtcg 61501 ttttgtttta tcttgtagtt tgattttaca ggttttccgt ttacaagtat cattccatcg 61561 tttataagct tttgtatata cgaccttgaa taatctttga cctttccgca aagccacgca 61621 tcaatcctta tcccgctttc attggaaaca agtataattt cttccataat tacctgtacc 61681 ccgaattatt catttatctc gtaataatat atttaaaaca atctcttgta aaacaatctt 61741 ttattattct tcaaaatata ttatttatta cttttaatac ttttaaatta tattatttct 61801 tgtcttcctt gtatataaac aaagtataat aggctaaaag cagagttcca accactacaa 61861 aagtatctgc aacattaaat acgggaaaat ggtaatttcc aaactgaaaa tcaagaaaat 61921 ccacaacccc gtcggttcta aataccctgt caataagatt tcccaatgct cctccaagga 61981 tcatgctaag tgagaatctg taaaacttgt tgctgttttt aaaaataaag tatacaatta 62041 aaattgaaag cactaccgta acgggaacaa gtatatatct cccgttctgc atgatacccc 62101 aggcagcacc ggtatttctc cagtgagtca gataaaaaaa gttgtcaatt acacttattt 62161 tgtctccaaa ttcaatattc ctgacaacaa tatactttgt caactggtca gcagccacaa 62221 aagcggcaat taatactatg aaaatcatat aagcccagcc ttcctcgaag atttatcagt 62281 aaaattatat acactttcca ttatgatgta aagtttgttt tcagattgtt actcaacagg 62341 tatataccac cgggtaaaat cgtaatattt gccccatatg ctgggattga actctcctct 62401 taaccttttg ttgtatataa ccatattatt ataaaaatac aatcccaaac aaggcacatc 62461 ccgatttatt atttctttca tgttaataaa ataagctttc ttcattgacg gatccttttc 62521 cttcaaaatc aaggtaagat accggtcaac ctcttcattg ctgtaaccgg aaatattaag 62581 ccctgtcccg atttgtgctg atgaatacag aaaagatata tccggaatgg atgccacagt 62641 gcatccgata agcgccatgt caaatttacc gctctgtact ccgttaagtt cgtcctccca 62701 tttgaccttt ttaatttcta tttctattcc cgcctctttc agctgttctt ttatcatttc 62761 cgccacggac agccgaactt cgttgtcatc atttaccata agctccagtg aaagcggagt 62821 gttaacaccg ttgattcttt tgtaaaatat accgttgctt tctttccatc cggcatctga 62881 aagtatctgc tttgcctttt ccacatctct ttcataagat acaacattgg tatcattgag 62941 ccatgtatcg ggaataacgg gcaaatccga cgccacagcc tcccccggca aaatactgct 63001 tataatctgc tccctgtcaa cagcatatgc tatagccgtc cttacttccc tttccttcag 63061 tattttgttt gagagattaa atgcaacaaa ctcaaattca ttacttacat atttttttaa 63121 aattatatcg gaccttccac tgtagcccgt ccaattggtc ctgtctaaag taatgacatc 63181 cacttgctgt gaatgaaaag cattcattac agactgattt ttgccatata tttttatatt 63241 gacctcctgg atatagggaa ggtcaattcc gttttcaata ccatcatctt tgttccacca 63301 attttcatta catgtaagcc tgatatactc accttgcctg tattccgcga acttatacgg 63361 tccggtacct atcggactgt tgtttttggg agtggtcaga atatcttccc caagaaaata 63421 atgcttcgga attacgggaa aagtcataag ttcgggagtg aaagaattgg ggctttttaa 63481 aagcacctta aatgtcctgc tgtcttgagc aagaaagctt tccacatttt caaaacatgt 63541 cttgtacgga ctgtttaccc ccgcattcat tataacgctt gccgtaaatt ccacgtcttc 63601 cgctgaaaaa ggtataccat cgtgccaata aatattttct tttaaataaa atgtccatac 63661 caatccatca tcggatcctt cccagctttc ggccagaagc ggcacagcct tctgatttcc 63721 gtccaacctc acaaggcttt caaacacaaa gcaggaatac tcctttacat aggcattgga 63781 agtcaatatg ggattgagag tgtcgggctc ggtggaaaac aaatttaaaa caccgttttt 63841 tacaggccct gtatccagta catcatccat accattattt aaaaaatcat agtcattgtt 63901 tccttcttcc aacaatctgc ttaaatcaat gctgcaagca gaaaaaacaa tacttgcaat 63961 caccagcaca acaaccaaca aggctctttt tctcaaagtg tatctctccc tgatcatatt 64021 ctttgtagaa ttaacttttt ccgggactta tcttttgcaa tttctttgct tgtattttct 64081 ctgtctgcaa ttttcctatc ttttttattt atcatccgtt tattttcata attccgacca 64141 tcgtaccagt tctgccgtta tctccccggt gggaaaagaa tatatccttg ttgcattttg 64201 tacatattcc gctcaaaaca atattttcct cttccacccc ttcttccagc aaagttctct 64261 taattattgc cggaaggtca aaatgccact tttggcctgt tctgtgacaa tactctgtgc 64321 cccagtcaat tttcgctcta aactcatcat atacatcatc tcccacctca aagcaacatt 64381 tgccgatgga cggaccgatt gcggcaacta tattctcagg cttgctggaa aatacatctt 64441 tcatcttttc taccgcttcc tttgctattt tcatcaccgt gccgcgccat ccggaatgag 64501 caattgaaat aaccgtcttt tccgggtcaa aaagaaaaac cggaacacag tctgcataaa 64561 atgtaaccag agtaacctct tttgagttcg taacaagacc gtcataacct ataatgtcac 64621 tttctctggt tatacccttt cccctgtctt cttccgtcac cacacgaatc ctgttttgat 64681 gcacctgatt tgaaaaaacc atgctttcaa tatcaaggtt caaggcgtcc gccactcttc 64741 tgtaattctc ttcaacattt cttctgtcat cagttttgtt aaaggccata tttaaagaat 64801 cataccagcc cttgctcact ccgccccgcc gggtggtaaa gcagtgagtt ataatattct 64861 catatttcag caggttgtta aactgaataa actccacctg attcttcgtt ttatacgtaa 64921 tattcttgtt cgatgcaaat ctgttatcca aaacaggcat cctccatatg accaaattat 64981 attccgtgtt tatactgagt ttgtatcatg atgtttacta tatatatgaa tatatatgaa 65041 taatagcata tattattcct cttaacaaca tcccgatata tacaatattt tgaagtaaga 65101 ttaaaataat aaaaaataaa ataaagactg tacctcacat tttatctctt agtacagcct 65161 tttattcagg ttgtgctttc ttttcaattt caataacctg gacaccacta aaaaattcct 65221 ttttttattg attacaaact caatcatgtt tttctttctc attcatggaa gaaatatgga 65281 agtgcatcat aaatataatg tcttacgtat ccccaccagt gagtggcgcc cggagctaca 65341 agaaagtaaa aattaccttt ggaaaaatcc gaagtataat caaaatgcgg caaagccttc 65401 atagcttcaa tttgaggatt catattagca tatgcaatat cctcggaacc ggtggccgca 65461 aatacgaaat actccctctt tgaaagtccg gatctgttaa ttgcttcagc aattgaatta 65521 gccttatcct gcggactgtt tccataccag tagtcaccgc ttaaaggcat aaaatatgca 65581 acgtaatcaa ggcagttaac cattacatac catgttgtca atcctcccat tgagaatccg 65641 ccgaaacctc tgtgcattct tgaagcggct attccctgtg gggttgttga ttctgcataa 65701 gtagagtact tgctttccac aaaaggaatg acattttgcc tgaattcctg ataaaagttt 65761 tgggccgtgc agtttccgcc gttgaaagtg ggtgttacta caatcaaagg ctcaagttca 65821 ccgttcataa tcgcgtggtc aaggatattt tgcaatttaa catcgttgct gaaaatcgta 65881 ttctcatttt caccgccgcc atgcataagg tagaaaatgt tatatttttt gttcggatca 65941 taaccgtatg gaagatatac attaagactc ttagttccgt ttattcctgt atatgtttcc 66001 ttgacaattc ttcccgcctg cggacaaggg tttaaataag aatcaggagc cggccgatat 66061 tgcacggccg actcatattt aaaagaagaa gaaggatttt ctgctacagg aaatttgtcg 66121 attactctta aaaggtagcg tgaaagaagt aaaacatcag tgctgtttat cgatccattc 66181 ttgtcaacgt ctgctctagc ctttgcatcg tcggtaaggg tgattgccct caacacgctt 66241 ctctttaaca ttgtcaagtc agttgagtta atggttccat caccgtttac atcgccaagc 66301 agtaccggag gctgtgtagg ctgtggagca ggtccttcga ttacagttcc ggcaaccgct 66361 ccgattgcct catctatgta gaagttaatg gtgtcatccg ctgtttccac ataaacatac 66421 atatctgttg catcggaagg aattctgtat tgcggattgt acaggtgaac ccactgattt 66481 ggacccacag ttttcatatc tatggtatca taccgttgag tgccgcttcc gtctacgtat 66541 tgcagcttca tgcagaatgt tgtggaagac gcaccttcaa taaacgatgc cactacgctg 66601 aaacaatatg tgtttccggg aacaaacgtt ctgggattca gcgcccgttg tgctccgttc 66661 catgctgccg tacggttcct taccaagagt gattctgaac ctttgtaagc cgttcttccg 66721 ctaagcagaa cttccgcagg tcctctggct gtccactgtc ctacgcttcc ttcaaaagtg 66781 tcatgataat aatatccgtt tgcatccggc tcttccggtt tgcctcctcc tccgccgccg 66841 gccggattgt taccgtcgcc ccattcggac tgaggaataa tggatgcaac cgcattgtat 66901 gccggtttcg gttgattgtt tgcgttaaac aaaagaggtg cattttgtga accgagccaa 66961 gtattggcgt cattaggtcc ccatacacag acagccgtaa cctttccttt gctggaggtt 67021 ctgtttatat caacagctgc ctggaaaaca gctttatatt tatcagcctg ctgctgtaag 67081 ctaaatttgc cgttttctgt actaatatca agctcggtaa tttggacatc acaaccgata 67141 tttatatatt tctgcaaagc tgctttataa ttttgtatac ctgagaatcc attcatatcc 67201 gcattaatat gggactgcat tcccacaccg tcaagcaagc ccttgttgta caagtttgca 67261 caaattgagg caatacagtc tctcttatga tcccaatatt cgttgtaatc gttgtagtaa 67321 agcttacaat ttgccggagc atattttctt gcatatgtaa atgctttctc aataaatttg 67381 ttgtctccgt agatctgaac ccatggagat ctaccatttc cgtatccagg ttccctcgcc 67441 ccgccataat atctggtcct gtttgcatca tcacttactg cctcatttac aacgtcatag 67501 gcataaagat tcaaagacgg atactgtctt tggatttcag caaacatatt ttttatgtag 67561 ctttccaaac gctggtccat aactgattgg gaaacccagt ttccgttgtc ctggaaattg 67621 tctttgaaaa accattgagg tgtctggctg tgccaaacca gtgtatgacc tctgacggct 67681 atattatttt gtgcacagaa gtttaaaata cttgctgcac gattaagaga aaccctgata 67741 tttgtattgg ttgatcctga ttgaaccagt gtggcatcag gcttcatttc attttcacag 67801 gtaatactgt taaactctct taaaatcaag gcctttattg atgaattgtt taccgttccg 67861 gagttaagta ccgaaccaac tctgaaatag tttgcataca tatctttcag cacagcgttt 67921 gctgcatata ctgtgtttgc ctcagccatt cctttacggg ttatggttac atcgtcaaaa 67981 atgaaatcta cagtgctgtc ggttgtaatt gacaaagtaa tattcactgc agttttgggt 68041 gctttgtatt ttgccgaaat ctcagtccat tctccggcca caacatcctt tgttgcaatt 68101 acttccttat tttcttcttc tgtttccgaa tccaaatagg acacagaaag tttgaaagtt 68161 tcggtgccgg tcccgttgtg ttttacaaaa acactgtact tgtattctac accaccgtcg 68221 agatagaaac ctttttccga atacgcaccg tcactcgcac tggagcgatt tattaccatc 68281 atacctcttg taccgttgtt tccttcattt tcaactgccg ttaaatatgt gtcgactccc 68341 aagttacacc atccgtcaaa gttaacttca aaagtgtcat gaaccacttc ataatcagca 68401 tatagctgac ttatgtttga cggtaataca aaaaacactc ccagcaatac cacaagagcc 68461 gttatttttg ccaaaactct cttgtttttc ataagcaacc tccttttaaa ttttaatttt 68521 taatttaatt tataaattaa atttaaataa acttaagcat gctctaaaca aattatatca 68581 taatatctat tacgaattac attcctcctt ccattttagt taaaatccac attacactat 68641 aattgcctgt aattctttgt atttttataa agggtgtttt aaagtttctt agtatttggc 68701 caatttcacc ccccctgact tcttaaaatt tcaattgaac ttaaaatata ttcacttctt 68761 ccattctttt atgttattta ttcgaaaggt attgaatttt tacgttggga attttaaatt 68821 aaatgtcaat tttttttaaa aaaaatccgt gttgtaaaaa ataatccgcg caaagaagca 68881 aaacctttgc atattggcaa acagcataaa taattgtcat ataatacttt cgtatggtaa 68941 aataagtaca aagtttttat tgaacctgtt tggacggccc gtataaataa tatactgtcg 69001 aaaaggagac aaatagcatg acaaacaatt taaaaattat tctagcaaag cagaaagaaa 69061 tcataacaag tcttgaaaat gaaattgccg gcatcgaagc caacgacctt gtaaaagaaa 69121 atcaaaaatt gaaagaagag ctggcaaaac ttaaatcaag tttggaaaag gaaaaaattg 69181 agaacgaaaa actctcaaaa gaaaacaaaa atttgagaaa cattttgtat gaacagttct 69241 acaacgaaaa aatcagcctt ttgaactcag cggaaaaaag aatggacgtt tattacaggg 69301 ctcatgtgga aggagaaata aacaggctga caagatttga attgtcggta aaaagacgta 69361 ttgatgaaat gacaaaagta cttcgggcca acagagtaag ccttcaggat gaaatttaca 69421 taaagcttga ggagcttaga aatcttctta acgttaaaat aaccaaagcc cgtgaagaaa 69481 tcatgcaaca gaccggagca tttattcaaa acagaaacga gggccttgca aggctaagac 69541 aggaacaggt tacggagcag gaaataaaag cccgggcaaa gcaaaacaac attgaatcca 69601 ttataggact taacataatc aacaaagtgg gtatattttt actcattgta ggagtaataa 69661 ccgcggcgca atttacatat ttcaggctgc ccgatacctt aaaaagcgtt tttacctttg 69721 cagtgggcgt tgttctgctc atagccggtg aaatattaaa ccgcaaaaag cccaacgttt 69781 tctcactggg cataaccagc ggaggtattg caatactgta tgtggctctt tgcctcagtt 69841 attttcaatt taaactgctt gaaacatatc cggctttagg attgtgtatt ctcataacgg 69901 caggaacttt tgtcctttcg cagaggtaca attcccagac catatcggct tttgcactga 69961 tcgggggata tcttcccatc ttctcgataa ccggtattag tgcaatagca tacggtgcca 70021 tggtttactt tgtaatactg aatcttttgg ctcttattat tgctgtcaac aaaaaatggg 70081 ctgtcactgc atacatagga tttgtgctga acgtcatagg ttccgtatat atagcatcaa 70141 taatgtttgg aggacttttc gcaccatcgg aattttcatt cgattccgtc attaccataa 70201 tttatatttt gttcgctttt gtaatttata ctctgatacc aatagcggga accttcaggc 70261 aaaaattgag ttttaaaact tctgacattg tactgctcgc attaaacaca tttatcagca 70321 gtgtacttct ttactggtca ttttatgcat ccgacctcga agactttacg ggactttttg 70381 ccctcacctt tgcaattatt tatcttgccc ttggaaggtt tattgaaaaa aacatgccaa 70441 aggaaaagca ggttaccgct ttgttttatc ttacaggact tacctttgtc gtacttataa 70501 tacctttcca gttcggcaaa gtgtggctgt ccctgggttg gctgattgag ggtgttgccc 70561 tgctttccta cggtatatgc aaagaaataa aaagatttaa aaaagccgga attgcaattt 70621 catttttgtg cctgttaact ttcctttcct ttgacgtgtc actgattcaa gattctcttt 70681 ttacctttaa atattttgca ataactttgg gcagcatcat cattttagga gccctcatat 70741 acaaaaagaa tctggcaagc aaggagtcaa aactgttcaa gtatgccaca tccataaatc 70801 tgctgatctt tttgctatac ataatcagca acgaactaaa accattttta tcccaatatg 70861 ttcaggacac aaaatttgac ctggattact tgatctgctc ggcaatgatt ttaacaagct 70921 ttcttgtggc atacaccctg ccaaggataa aagttttgtg cgacaatgtt ataaaaggca 70981 tttcaatgtc tatttatgct ttggcactgc taaccctctt ttccctgaat ttcacctccc 71041 ccgtgaaagg atatttggtc gaaatgcctt tggctataag tattgtcgga accctggaac 71101 ttgctttaat agctttcctg tccatccttg ccgtaaggga tttggtattg tattttgtaa 71161 ttgaccacaa actgggtatt gaatggtacc cacttgcaat atctctttac tttgtaataa 71221 tactgactca aaatttaatt acccagtaca ggcttgaatt cagcaacgcg gcaataagca 71281 ttatttacct tgccgcagct ctcacatgga taatattcgg ttttgccaaa aggtatgtat 71341 tcatccgccg tttcggactt gccatgtcca tgctttcggt ggcaaagctg ttcattatcg 71401 accttgcttt cctgacccaa ggttacagaa tagtatccta ttttgtgttc ggcataatac 71461 tccttgcaat atcttttgta tatcagtatt tcaacaaaaa attagaaaat atatgcgagg 71521 taatgcctga tgataaaaag aatagtaatt agtttgcttc tgttcattct tctttttgta 71581 tcaaatgcat atgccgttga ttttagttac agcgcccgta ttgaaaacgg tggaagcaaa 71641 aagtacaaag cgattcgaat tacacctaaa atatacaaca atatcaatgc aaacatggca 71701 gaccttgtgc tttacgatga aagcaacgaa ccggtgccct atttcataaa cagctttaaa 71761 gaaatcaaaa ccgaaacgca aaaaagctat gcaatgaaac ttgtcaactc ctttgtaaaa 71821 gatgaatatt attatcttga ctatgctttg gaagaatttc ccgatgaaga cataattgcc 71881 acatccattg agattaaaac cgaaaacagc ggctttgcaa aaagagttga agtcttcgga 71941 agctacgaca atgtcaactg ggaaaaagtc aaggaagaca tcctgtacag cgtggaagga 72001 atcaaaaaac ttgaaataca atttgacagc ataaaaaaat acacccatta ccgctttaaa 72061 atatcaaaca atttagagaa aatctccttt tcgtcggtgg aactgaaata caacctggtt 72121 taccatgaaa aagaatattt tacggaaacc ttaagccctg aatacaacgt tgctgagcag 72181 gaaaacaaaa ccgtcataaa aataaaagat ttgaaaaacc tgaaagtcac cggcattact 72241 ttaaaaacag acagtacttt caaaagagaa gtaacctttg acggccggat atccaaaacc 72301 ctttacaatc ttaatttcaa cggcatgcag tacaccgatt tgactattgc cgtggaacct 72361 tacagaatta cttccgatac tgccgaactg gtaatagaca acaaagatga caaaccgata 72421 aacgtcgagg gaattgaaat tgaatacctg tttgacgaac tggtatttga aggctccggt 72481 tcgaaagagt atgttcttaa gtttggcaac aacgaaattt tgactccgaa aagctatgac 72541 atttcaaatt acaaagagta tattctggac gaaggatatg atatcttaaa catcagggaa 72601 attgtcgaac tgcccagaaa agagcctgaa accaagccac cggaatacga ttacaagctg 72661 atttttaaca tatcaatcat cctggttgcc gtaattatgg ccgtaataat attcttaaaa 72721 ataaaaaagt agtttgggta agctgtctgt tttatatttt taaacttgca tttttgtgtt 72781 aaaataaaat attaatatat tactgtcagg aggcttaata caaatgagta atacatcaaa 72841 tacgcatata aatttggaaa acggcagatt aaatgttgaa attgcccgtc cgggttcggt 72901 atacaacggt tcccgctttg attggaccgc ttttatcact aaaatagtgt tggacaacaa 72961 atattccttc tgcgcacccg agtccgagat acccggccag ggttcgggag gatttgggtt 73021 atgcaacgaa tttggaataa acacacccat aggctacgat gaggcaaaac cccaggaaaa 73081 gtttccaaag ctgggcaccg gtcttttgac ccgcccggat gaatcagact atttcttctt 73141 tgacaaatat gaggttgagc ctttccctgt taaaatttca gcggacaaaa acgccgtggt 73201 gtttgatgtg gagcctgtga actgcaacgg atacgccgtc aaaatgacca aaaccgtctc 73261 tatagaaggc aatatactca ccatcgacta tcatcttgaa aatgtgggaa gcaaacccat 73321 aaaaaccgag gaatattgcc ataatttcat ctccgtaaac aataaaagaa taggagacgg 73381 atatgtactg aaattccctt acaatataaa acccaaagaa ataccggaag tcatgaacat 73441 aaagggcaat gaaattcgct ggaactttgt gcccaaagga gatttttact gccagataga 73501 aggtttcaaa ccgggggaga aacattactg ggagttgttg tacgaacctg aaagagttgg 73561 aatcagggaa tacagtgaat ttgaaattgt aaaagtcgca gtatggggta ccacccatgt 73621 cgtaagtccg gaagtattta taaatgtaga tattgctccg ggcaaaactc aggaatggag 73681 aaggcagtac gagtttttca cttactaaga cttcagtttc cggattttaa aaagcgggaa 73741 gcttttatta agcttttccc gctttttatt actccatttt ttttgttttt atttctttta 73801 tttgtgattt tcttttttta tttatccatt ttacttatct tctttctctt tacttgctat 73861 ctttgcccag gtatccttga gtgtcaccgt tctgttaaat accaaagagc cttcctttga 73921 atccaccaaa tcaacacaga aataacccaa acggaggaac tggaacgcat ctcccggttt 73981 tgcaccagca aggctgggct cgagcttgca cgattttaac acttcgagag aattgggatt 74041 tagctgttca ataaagtcaa cattttcatc agcaccggga ttgggcacgc taaacaaatg 74101 atcatacagg cgtacctcgg catcaatggc atgagctgcc gaaacccagt gaatggtacc 74161 ttttactttt cgcccgtcag aagcatttcc tccacgggat tgggggtcat aggtgcaatg 74221 tacttctgtt atctctccgg ttttgtcatc ctttacaaca tccacgcatt ttactatata 74281 agcgcctttg agtctaacct cctgaccggg cgccaggcgg aaatatttct tcggaggatt 74341 ttcgcaaaaa tcgtccttct caatataaag aacttttgaa aaaggtactt tcctggttcc 74401 cgcattcgga tcctcgggat tgttctcaac ctcaaactct tcaaccattc cctcaggata 74461 gttgtctatg acaagtttga gaggtctcag taccgccatt accctttgag ccttctgatt 74521 aagttcctct ctgatacaat gctcaaggag cgatatatca acggtgctgt tgctcttggc 74581 aacccctatg cgggcacaaa agtttcttat ggccgaagga gtatatccac gtcttctaag 74641 tcctgatatg gtaggcattc ttgggtcgtc ccatcccctc acatgccctt cctgcacaag 74701 ccttagcaat tttcgtttgc tcattaccgt ataggtcaaa ttcaaacggg caaactctat 74761 ctgacgggtc ttgcactcca tgtcaagggt ctccaaaacc cagttgtaca aaggcctgtg 74821 gtcttcaaac tccagcgtac agatggaatg ggttataccc tcaagagagt cagatatagg 74881 atgggcaaaa tcatacatcg ggtaaataca ccacttgtca ccggacctgt gatgacttgc 74941 ctttataatt ctgtaaatca ccgggtccct catattgaga ttgggggatg ccatatctat 75001 ttttgcccgc aaaaccctcg aaccttcctc gaattcaccg tttttcattc tcataaacaa 75061 atccagattc tcttcaacac ttctgttgcg atacgggctt tcctttccgg gctcggtcaa 75121 agttcccctg tattccctta tctcatcggc actcaaatcg caaacataag cctttcccat 75181 tttaatcagc ttaacggcgt attcaaacat tttgtcaaaa taatccgatg catagtacaa 75241 tctgtcttcc cagtcaaaac caagccattt aacatcggct ttaatggact caacatattc 75301 agtgtcttcc ttcgaaggat ttgtatcgtc aaatctaaga ttgcacaaac cgccgttctg 75361 ttctgcaatt ccgaaattaa ggcaaattga cttggcatgt cctatatgaa ggtagccgtt 75421 gggctcgggc ggaaacctcg tatgcactct tccgccatat ctatttgttc tattatcctc 75481 atcaataata tcctgaataa aatttgaata tactttttca ttttcttctg ttgaatttaa 75541 ttcatttgct ttgccatcaa cctgagcgtc cattcccttg ttcctccttg tcagttttaa 75601 aatactgccg catttaactt atgcagattt atgtaataga catttgttaa taatataatc 75661 aactataaac atatttatta tattatatat cataatggaa ttcattcaat atgtttttag 75721 tattattaac caaatttcac catgtagtca cagtttgtcc ttttttctat tttaaattat 75781 gcagctcttt ttagcaacat caattataca agatattatg attgtactgc tttaaatcag 75841 gaataccatg tgtggaatca gttttacgct ttccctgatt tctgtatttt ctaaacaaac 75901 aataagcaaa aaggggctat tttaaaaatc tattttgaaa cagcccctct aaaaaatcat 75961 tacaatcaaa aacttaatac attttgtaac aaaagactat atagttataa gtcccaaaat 76021 atacttctta aggaataaac agtcagtaga attaactttt ccgtctttat tgacatcagc 76081 cacattcaaa tctattacta atttattccc ccttaacaag taattcttca gcagtatata 76141 atcttcgtcg ttaacaattc catttctgtt taagtcacca ttaagcacaa caggcggctc 76201 aataatctct ccattatctt ccggaaattt aactgtcgct tgtattttct tttcaacagc 76261 gctaccttcc aaacgcaaat cgatatctac cgttccggga agattacctt tcagtttgag 76321 ttttccgcgt cccctttcat ccagtagaac atcctctgca gatactattt cttccattcc 76381 ggatgttacg attatctttt tgccttttgc tgcttcttcc ggcagtacac gtatctctat 76441 tgcaacagtt tttcttaatt caatttctac tttatctaat atttcgattg attttggttc 76501 agctacaatc tctatatcgc ggatttcagc tttttgcatc gcaactccag catagcttgt 76561 tatgctctta gaaatattaa gagtgtattt tccttcaaaa gaagtctttt ctgcaggaat 76621 tagtttaatt ttcttagagt aatttccctc ttcatcttca tatactattt taatgtttac 76681 cttattttct ccctgtttca gctgaataga ctctgaatcc agcgttgcgt gctttacata 76741 tttgctaaat gcaatttcta tatattccgg atatgcataa atgtgtccaa ccttcggtgg 76801 ttcatacgaa accaaaggaa tattaacatt ggtctgcaca ggaggcacag gtaaaatctc 76861 actatatgct gtttcatatc cttccttttc gacctttacc tgccacattc cttcaggaac 76921 atcccaggca taaaaaccat tctcgtctgt cagcaatgga ttcttctggc cgaattcttc 76981 cgcattccat aatatcattt ctccgttttc atctttatag tatactgtga ctgtagcatc 77041 ggttattctg ttgtcaggta cagtttcgta tacatatcca cttggatcta ccagagtttt 77101 ttgttcttgt aatggtagct taatagatga tccttttcca gattttgtgc ttttgcctga 77161 ttctctatca tcttcatttt ttccaaatat atcttcccat aacttatcac caagactgta 77221 ctgatcatat ttatcaataa ctatgtctat tattttatgc atcgtgccat ttctggtatg 77281 tccatccata agtgatgcaa taaagtttgc attcacagta aaattataca caccagatgc 77341 taaaaacaaa tcatcgcgga gcctttcttt atcttcgctt gaaatgttct cagattcttg 77401 caattttttc tgaacataac ccatatctgt aactgcgttt gccggtgtaa atgcaatagt 77461 attcaccgct gtaccaattc cggaaataaa atctattgct tccacaacct ttccactacc 77521 agcaatatta cctaattccc caattattgt agcagccata ctaatacgct catcttttgt 77581 aactaaaggc gtctcttttt gtgaagattc atcatcgtct tcagacttta cggaatcttc 77641 tgtcttattg ctggctaatc ttacttttga tgtaaaaatt ttattttcag tctcgtcttt 77701 tattaataat actgctccta gttttccatc tatttcttta aataaatacc ccattttttc 77761 gtatttttct cgttcaattg gctgatcacc tattacaatt gttacaattg caatgccacc 77821 tgtatcttct ttcagcataa atcctatttc attttcatca agtaatccta ccatgacatt 77881 ttcttttttt aattcataaa gaaattgatc tgcaaaagtt gaaatctgct ctaaaacctc 77941 taaattcaat tcaccatcct ctttaattaa tcttttcttt tttaaattgt actctacagt 78001 aaacgaaccc ggaacatgat tgtaaccaaa acttcctgtt gcaatccagc tcttcgattg 78061 tggatcatat tttgcatcca gttttctttc ttcgccgttg cggttgctta caatacacaa 78121 attttcaatt tcttctgccg aatcaccaac aaagtccaca ataaaagtat aggattgaga 78181 aggaacataa gtatatactc ctttaggaac tatttcacca tttttataca atatcagcga 78241 ctgatttgag tggatcgtgg ttactttctc aatctccgga acggactttt tataaataac 78301 ttcaagtgtc tcagattcaa taacctggtc attgtattca atccttgctg acaagttatg 78361 aactgaataa gatttgtctt tgcccagcga aacttggaaa ttccaagcac cggtcgaatt 78421 agctttggta actccaacca agcttccctc atcatatatc ttcacttcca ggttgggaag 78481 tgtctgaccg gttacataaa ctttttccag gcttgtaaca ttaggagctc ctattgtgag 78541 gtaaggaaca acttcgttaa cgacacccag aggttctctt acagtccttc cttccgcttt 78601 aaattccaca taagcattac tgtaacaaac aaccgcttca gtaggtctga tattaaagcg 78661 tacaacacct tctgtttttg tagttgttac ttcaataaaa ctaccggata catttactga 78721 atcaacaagt tctccgtcaa tagttaatgt atcttttaca taaaatgttt gatccggaac 78781 cctgaacagt aatttaactg tctgtgattc aataggtttt ctgaatgaat atttggctct 78841 aagcactata tcttttccta tacgattatt ttccgaaacc acagcatagc ttgcaacatc 78901 gggatctgtg aagaacaact ctttttcgtt tagttcagga acaacaatca gtcccaaatc 78961 tttaatttcc ccatttttta tttctacttc cttctttacg aaatgtatac cttctttcag 79021 acctatttcc tcaaattgct ccagtgtatt aagtctccac aagtagttgt tgctggagat 79081 gaatacaaaa gtatacactc cttctttcaa aggattggag attattttac cctctctgtt 79141 catcgaacag ctttctatga actttttgtc agagttataa accattaatt cacatctttg 79201 gttccccgac tgtattgatg ccattccttt tccgttctct tttgcaacag cttgcccgct 79261 cgcattcatt aatctgtcta aagtaagctc gatcgtagcc ggcaaagtat agtccttctt 79321 gtgtgtaaac gttacttcaa taacgtcacc tgtttctatg ttagtatcat ttaagaaaat 79381 ataaggtggt ttgatattaa agtttttgat ttttgcctgc tttgttttat tgtatatact 79441 aatagtataa ttgtataagt tttcttgctc caatccaggc tcttcctgag atgtatgtgc 79501 cggtttcttt aataattcca aggtcaacct gcccttgtaa ggtgtcaatt gaatttcacc 79561 caagtcaagg gaatcaccat taatttctgt tgactcgtca aatgctttaa gctccagatt 79621 catgtattgc tcatggctga tacccagtgt tgttttgccc attgcaactt ctatactaaa 79681 tcttccggca ttatcggtta caagtttaat atagttgcca aattgattat ttaataattg 79741 ggaaacatta atattggcgt tttgtacagg tatacccgtt tcatcttcta caataattcc 79801 cgttaatgtt attattttca gcttctccag gcgcagagtc aacacactct ctcttttatc 79861 aattgctaca ttgtattttt caacaggatt tttgaatttt ttccctagtt cttcttttag 79921 tgtcaagccc acagatattt cctttccaac aaagatgtgt tccaattctt ttcctgtgcc 79981 aacttgcttg aaattccttg cagggtcata gaaagtcaaa ttatatcctg actcaactat 80041 atttccttca tcatcggtta caataaccgt tagttttgcc ggttcttcta tcaatttcac 80101 aataatagaa tcattgatgc ctttactgat agatatgttt tctattgtac ctgccgtaaa 80161 tccattttta gattcaatgg ccaatctata atcatcagca ggttttaagt tagtaatggt 80221 atagagagta tcccctgtta tttttcttct ggcttgctca tttagtcctt tactttctaa 80281 aaccaaatcc attcctgcaa atttttccaa tttggataca ccgcttaaat caatcgatac 80341 agtggctcca acttccaaag gaaatccttc tttttctttt ccaagtgttt tagtgtaaag 80401 gtttccttca gcatctaaca aattgatttg aatcttttga atttggtcta tgtcttctgt 80461 aaccttgaaa tatgcctgat attttcccgg tccatattct ttcattggta cagtaataac 80521 tttttcgtct gcacttcctg tcttggagat acacttatag tacacaaggg cctctgcctt 80581 cgaattttct tctcccctca tgcggatatc tatagtgtcc cctattgcta cagtatcatt 80641 tttcttttca attgtaaccc aatactgatg aattttttta gattgattat agtccaagtc 80701 tatttcaaga ctattccaga atgttcttcc ctccggtacg aaaatgtaat ttccatcctc 80761 tatggggttg attaatatca attcattaaa tcggctattg gattcttcca ttgtaatgat 80821 ctgctgtcct tcaccactta gaataacttt gtgattttca caagcataaa aggatggtgt 80881 aactccgcat gctatttgcg taaagtctcc ttttacctcc agcactccct ctgatatcac 80941 ttttgagtct tcggtctgg //