LOCUS NZ_ACVX01000014 77760 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00043, whole genome shotgun sequence. ACCESSION NZ_ACVX01000014 NZ_ACVX00000000 VERSION NZ_ACVX01000014.1 GI:256004481 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 77760) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 77760) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000014. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..77760 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene complement(<1..1492) /locus_tag="ClothDRAFT_1322" CDS complement(<1..1492) /locus_tag="ClothDRAFT_1322" /inference="protein motif:PFAM:PF00041" /note="PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="Fibronectin type III domain protein" /protein_id="ZP_05429461.1" /db_xref="GI:256004482" /db_xref="InterPro:IPR003961" /translation="MRKFNRCVAIVLVVLLIGMTFDVPSFFPYRIQQVYAEKEQIDSG ESVAESVYKKIETYDDIPVDIEPPKPPANLQLISKTSSTVSMSWSPAEDNTGVSYYNI YNGSSVVQAVYGENTSCTVSGLLPFTQYSFTVRAVDESGNVSAPSNTLVVTTLRESIR VNSNMALFEDKIYQDLYLESGSLNLNGYNLTIEGNLIHSGGTLNINGGKLIVKGDYRI QKESVNAQGQITYGGSDGILHMTNENDYVCVEGNFVTQSYYSHSSRLTDGVLEVKGDF IQKKHQSSYAYRDNFYASGKHKTILSGEKLQKVSFETAESRFNILELRNYSEDGVEFN QPLNANTFIDNGCKVKFAGSGAIGWTLADDETYEGDLYLGGGVLDLNGHELKVTGNLI QSGGTIDINGGKLYIEGDYRLQTENTDANGNKTYTYSNGYLKMTDSGSYIKVGGDFIT QSQNSHEGYLTEGVLEVKGDLIQKRQNAYNNFKASGNHKVVLSGDEL" sig_peptide complement(1382..1492) /locus_tag="ClothDRAFT_1322" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.608) with cleavage site probability 0.284 at residue 37" misc_feature complement(1031..1291) /locus_tag="ClothDRAFT_1322" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:28945" misc_feature complement(order(1070..1072,1115..1117,1289..1291)) /locus_tag="ClothDRAFT_1322" /note="Interdomain contacts; other site" /db_xref="CDD:28945" misc_feature complement(order(1052..1057,1061..1066)) /locus_tag="ClothDRAFT_1322" /note="Cytokine receptor motif; other site" /db_xref="CDD:28945" gene complement(1778..4255) /locus_tag="ClothDRAFT_1323" CDS complement(1778..4255) /locus_tag="ClothDRAFT_1323" /inference="protein motif:TFAM:TIGR00396" /note="TIGRFAM: leucyl-tRNA synthetase; KEGG: gme:Gmet_2300 leucyl-tRNA synthetase" /codon_start=1 /transl_table=11 /product="leucyl-tRNA synthetase" /protein_id="ZP_05429462.1" /db_xref="GI:256004483" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002300" /db_xref="InterPro:IPR002302" /db_xref="InterPro:IPR013155" /db_xref="InterPro:IPR015413" /translation="MYYNFVDIEKKWQKKWLEEKAFAVREDESKKKYYVLEMFPYPSG NLHMGHVRNYSIGDVVARFKRMNGFNVLHPMGWDAFGLPAENAAIKRGVHPNDWTWSN IDNMRRQLKQLGISYDWDREVATCHPDYYKWTQWMFLQLYKNGLAYKKKAYVNWCPSC ATVLANEQVVNGVCERCKSVVGKKDLEQWFFKITDYAQRLLDDIEKLKGWPDKVKVMQ QNWIGRSEGVEVDFKVDGMDKAVRVYTTRPDTIYGVTYVVIAPEHPVVKELIKGTEQE QVCNEFINKMMFLNEIDRTATDVEKEGVFTGRYVINPLNGDRVPLYLANYVLAEYGTG VVMAVPAHDQRDFEFAKKYNLPIKVVIQPEGQELDASRMTEAFVEVGYLVNSAEFDGV RSDEAIGKIIDYIEQKGYGKRKINYRLRDWLISRQRYWGAPIPIIYCDDCGAVPVPEE DLPVILPTDIKFSGVGESPLSTSETFISAPCPKCGKMGRRELDTMDTFVCSSWYYLRY CDPCNDKAPFDKERIRYWLPVDQYIGGVEHAILHLLYSRFLMKVLYDLGYVDYDEPFT NLLTQGMVLKDGAKMSKSLGNVVSPEEIIEKYGADTARLFILFASPPEKDLEWSDQGV EGCYRFINRVWRIVNEFADAVKEGGNIDTSTFTKADKELWYMLNNTLKRVTDDISQRF NFNTAISAVMELVNSLYYYKDKVADDSKNKALVREVIEKLIIMLAPFIPHATEELWSA IGKEGSVHEQKWPSFDPAALVKDEIEIVVQINGKVRDKIVVPSDLTKEQVEERALNSE KIKAETAGKNVVKVISVPGKLVNIVVK" misc_feature complement(1781..4255) /locus_tag="ClothDRAFT_1323" /note="leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390" /db_xref="CDD:178996" misc_feature complement(<3587..4162) /locus_tag="ClothDRAFT_1323" /note="catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812" /db_xref="CDD:173906" misc_feature complement(4106..4117) /locus_tag="ClothDRAFT_1323" /note="HIGH motif; other site" /db_xref="CDD:173906" misc_feature complement(2399..>3001) /locus_tag="ClothDRAFT_1323" /note="catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812" /db_xref="CDD:173906" misc_feature complement(order(2507..2509,2513..2515,2534..2536, 2543..2545,2630..2632,2642..2647,2651..2653)) /locus_tag="ClothDRAFT_1323" /note="active site" /db_xref="CDD:173906" misc_feature complement(2504..2518) /locus_tag="ClothDRAFT_1323" /note="KMSKS motif; other site" /db_xref="CDD:173906" misc_feature complement(2033..2401) /locus_tag="ClothDRAFT_1323" /note="Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958" /db_xref="CDD:153412" misc_feature complement(order(2147..2149,2159..2161,2168..2170, 2177..2182,2189..2191,2201..2203,2357..2359,2369..2371, 2378..2383,2390..2392)) /locus_tag="ClothDRAFT_1323" /note="tRNA binding surface; other site" /db_xref="CDD:153412" gene complement(4372..4713) /locus_tag="ClothDRAFT_1324" CDS complement(4372..4713) /locus_tag="ClothDRAFT_1324" /inference="protein motif:TFAM:TIGR00090" /note="TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: saz:Sama_2586 iojap domain-containing protein" /codon_start=1 /transl_table=11 /product="iojap-like protein" /protein_id="ZP_05429463.1" /db_xref="GI:256004484" /db_xref="InterPro:IPR004394" /translation="MESRELAEKIVSILEEKKAKDLNIIDIREISILADYFVICSGTS TTHIKTLADEVEEKMLEAGIELLHKEGYNSAMWILLDYGEVVVHIFHEEDRQFYNLER LWADGVMKHRQ" misc_feature complement(4402..4698) /locus_tag="ClothDRAFT_1324" /note="Domain of unknown function DUF143; Region: DUF143; cl00519" /db_xref="CDD:186053" gene complement(4875..5471) /locus_tag="ClothDRAFT_1325" CDS complement(4875..5471) /locus_tag="ClothDRAFT_1325" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: son:SO_4365 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429464.1" /db_xref="GI:256004485" /translation="MAKKKVRRKKKNRGSGFFSVVLFLLLAAGCYFYFFKNSSVEVDN NFDALMARIMKTETTPAATSPSPAVNTAESTPGVEPVTSASAEKLSTESPQETENIQE TPVVIQQKGASIHVINYTGQKNLGEEIRTTLENYGFVVSSGNGSSLKHVSSAIIEKKE NVSGEELGNLLNIKRIRKEIDPSSRFDFIIILGDDFNP" sig_peptide complement(5388..5471) /locus_tag="ClothDRAFT_1325" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.324 at residue 28" gene complement(5500..6069) /locus_tag="ClothDRAFT_1326" CDS complement(5500..6069) /locus_tag="ClothDRAFT_1326" /inference="protein motif:TFAM:TIGR00277" /note="TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region" /codon_start=1 /transl_table=11 /product="metal dependent phosphohydrolase" /protein_id="ZP_05429465.1" /db_xref="GI:256004486" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR005249" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /translation="MTIDEIKRKLESVLSPKRFEHSLGVMDTAVNLAEKYGGNVEKAA LAGILHDCAREIEGQAMFELCKKYHINVDYITLAQPELLHGPVGAVIAAEEYGIEDED VLKAIECHTTGRENMTLLDKIIFIADYIEPGRKFPGVEEVRELAYRDLNRSILLSLDN TIRYVMNKGAFIHPDTILARNFIIKESRS" misc_feature complement(5515..6069) /locus_tag="ClothDRAFT_1326" /note="Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism]; Region: COG1713" /db_xref="CDD:31899" misc_feature complement(5569..6042) /locus_tag="ClothDRAFT_1326" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076" /db_xref="CDD:185790" gene complement(6214..6834) /locus_tag="ClothDRAFT_1327" CDS complement(6214..6834) /locus_tag="ClothDRAFT_1327" /EC_number="2.7.7.18" /inference="protein motif:TFAM:TIGR00482" /note="KEGG: sat:SYN_02003 nicotinate-nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase" /codon_start=1 /transl_table=11 /product="nicotinate (nicotinamide) nucleotide adenylyltransferase" /protein_id="ZP_05429466.1" /db_xref="GI:256004487" /db_xref="InterPro:IPR004820" /db_xref="InterPro:IPR004821" /db_xref="InterPro:IPR005248" /translation="MEVNVKRIGILGGTFDPIHNGHLIMAEIIRGAFELDRVLFIPSG NPPHKKNQTVTDAEHRYNMVCEALKGNPYFEKSRIEVDREGYTYTIDTLGILNEQYRG IADLYYIIGADVLYDLLTWKDYEKVFGICKFIAALRPGTGKEGFRERIKYLEDRFSAS ILEAEIPLIEISSTMIRNRVKEGKSIKYLVPETVENYIKKEGLYLK" misc_feature complement(6223..6819) /locus_tag="ClothDRAFT_1327" /note="nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071" /db_xref="CDD:178839" misc_feature complement(6223..6813) /locus_tag="ClothDRAFT_1327" /note="Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165" /db_xref="CDD:185680" misc_feature complement(order(6322..6324,6421..6426,6469..6474, 6493..6498,6502..6507,6511..6513,6568..6576,6697..6699, 6760..6762,6769..6774,6778..6780,6790..6804)) /locus_tag="ClothDRAFT_1327" /note="active site" /db_xref="CDD:185680" misc_feature complement(6769..6780) /locus_tag="ClothDRAFT_1327" /note="(T/H)XGH motif; other site" /db_xref="CDD:185680" gene complement(6983..7444) /locus_tag="ClothDRAFT_1328" CDS complement(6983..7444) /locus_tag="ClothDRAFT_1328" /inference="protein motif:PFAM:PF00583" /note="PFAM: GCN5-related N-acetyltransferase; KEGG: gur:Gura_1522 GCN5-related N-acetyltransferase" /codon_start=1 /transl_table=11 /product="GCN5-related N-acetyltransferase" /protein_id="ZP_05429467.1" /db_xref="GI:256004488" /db_xref="InterPro:IPR000182" /translation="MEGIIEKALKEDLPDILNLQKKAFEKVAMEENNFNILPMTQTLE SITEEYEKRLFLKYTLEGKIIGSVRAHLDNDNVCHIGRLIVHPEFQNRGIGKALMKEI ESVFKNCTRYEIFTGLNSKNTVALYKKLGYVETSVKDVDGVFMVFMKKDNK" misc_feature complement(7043..7411) /locus_tag="ClothDRAFT_1328" /note="ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575" /db_xref="CDD:162430" misc_feature complement(7121..7264) /locus_tag="ClothDRAFT_1328" /note="N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301" /db_xref="CDD:173926" misc_feature complement(order(7157..7162,7190..7198)) /locus_tag="ClothDRAFT_1328" /note="Coenzyme A binding pocket; other site" /db_xref="CDD:173926" gene 8135..9307 /locus_tag="ClothDRAFT_1329" CDS 8135..9307 /locus_tag="ClothDRAFT_1329" /inference="protein motif:PFAM:PF00535" /note="PFAM: glycosyl transferase family 2; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: gur:Gura_2340 glycosyl transferase family protein" /codon_start=1 /transl_table=11 /product="glycosyl transferase family 2" /protein_id="ZP_05429468.1" /db_xref="GI:256004489" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR001440" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR013105" /translation="MKRKYGEQKLNKELVSVIICVYNGEKYIESSIKSALAQTYQNIE IIVIDDGSTDRTGEIVKNYCPDVKYIYQENKGVSEARNTGLRHCSGNYIAWLDADDLY LPDKIKEQVDFLQQNKDIDCVYNDAFLIDAHDNLVKVLRSDYGNLAPNDFLAQLLFRQ TIPCPPSTLYRRKCFENLRFIPGMRYAEDYWSSIQLAQRFKCGYLPKILYKYRRHDSN LTNNKEKQEEMEIKVVKSLGIDKIKDIVEKSSYPEHEKLLLLGKIFIKISEYEEACKA LEKIQVPDYIQDRKTKFLKYFYLGNVNYLTKEYNKAKFCYEKSLRTDPGKAEAYNNLG AALYHLSETEEALENFNKALALKKEYLDPQNNLKNIKTGGDLKITIRELRENLMVY" misc_feature 8180..8797 /locus_tag="ClothDRAFT_1329" /note="Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394" /db_xref="CDD:187019" misc_feature order(8192..8194,8198..8200,8276..8278,8423..8425, 8429..8431) /locus_tag="ClothDRAFT_1329" /note="active site" /db_xref="CDD:132997" misc_feature 9020..>9244 /locus_tag="ClothDRAFT_1329" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature order(9023..9028,9035..9040,9125..9130,9134..9139, 9146..9151,9227..9232,9239..9244) /locus_tag="ClothDRAFT_1329" /note="binding surface" /db_xref="CDD:29151" misc_feature order(9032..9034,9068..9070,9080..9082,9089..9091, 9134..9136,9170..9172,9182..9184,9191..9193,9236..9238) /locus_tag="ClothDRAFT_1329" /note="TPR motif; other site" /db_xref="CDD:29151" gene complement(9354..10613) /locus_tag="ClothDRAFT_1330" CDS complement(9354..10613) /locus_tag="ClothDRAFT_1330" /EC_number="6.3.4.13" /inference="protein motif:TFAM:TIGR00877" /note="KEGG: dps:DP2188 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201" /codon_start=1 /transl_table=11 /product="phosphoribosylamine/glycine ligase" /protein_id="ZP_05429469.1" /db_xref="GI:256004490" /db_xref="InterPro:IPR000115" /db_xref="InterPro:IPR003806" /db_xref="InterPro:IPR011761" /translation="MKVLVVGSGGREHALVWKIVQSPRVEKVYCAPGNGGISAIAECV PIKAMDIEGIVNFSKEKKIDMVVVAPDDPLAAGMVDALEEAGIRAFGPNKAAAVIESS KAFAKNLMKKYNIPTARYEIFENSADAINYLQDQKYPVVVKADGLALGKGVIIAQNFD EAKQAVQSIMEDKVFGEAGNKVVIEEFLVGQEVSMLAFTDGKTIKTMVSSQDHKRALD NDQGLNTGGMGTFSPSRIYTEEIDRYCMERIYKPTIEAMEKEGRKFKGVLYFGLIITK DGPKVLEYNARFGDPETQVVLPRLNTDIIDIFEAVIDERLDEVEISWNDSACVCVIMA SGGYPKEYKTGYEISGIEDAERDANIVVFHAGTKRENGKYYTAGGRVLGVTAMENTLD EAIKKAYEGVGKIKFQDMHYRKDIGKK" misc_feature complement(9357..10613) /locus_tag="ClothDRAFT_1330" /note="phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885" /db_xref="CDD:179154" misc_feature complement(10314..10610) /locus_tag="ClothDRAFT_1330" /note="Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844" /db_xref="CDD:145810" misc_feature complement(9735..10313) /locus_tag="ClothDRAFT_1330" /note="Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; cl03087" /db_xref="CDD:164032" misc_feature complement(9357..9635) /locus_tag="ClothDRAFT_1330" /note="Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843" /db_xref="CDD:145809" gene complement(10638..12182) /locus_tag="ClothDRAFT_1331" CDS complement(10638..12182) /locus_tag="ClothDRAFT_1331" /EC_number="3.5.4.10" /inference="protein motif:TFAM:TIGR00355" /note="KEGG: glo:Glov_2760 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region" /codon_start=1 /transl_table=11 /product="phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase" /protein_id="ZP_05429470.1" /db_xref="GI:256004491" /db_xref="InterPro:IPR002695" /db_xref="InterPro:IPR011607" /db_xref="InterPro:IPR013982" /translation="MIKRALISVSDKTGIVEMARELQSMGVDIISTGGTAKTLSDAGI KVINISDVTGFPECLDGRVKTLHPKVHAGILAIRSNEEHMRQLKELNIETIDMVIINL YPFKQTILKENVDLSEAIENIDIGGPTMIRAAAKNYQDVVVIVDPSDYAAVLEELKTT KDVSLKTKFKLAYKVFEHTSHYDTLIAKYLREQIGEDEFPQTLSLTFEKVQDMRYGEN PHQKAVFYKEVGANVGCITAAKQLHGKELSYNNINDANGAIEIIKEFDEPTVVAVKHA NPCGVASASNIYDAYIKAYEADPVSIFGGIIAANREIDEKTAEEINKIFVEIVIAPSF TEGALKILTQKKNIRLLQLEDISAKIPKGTYDMKKVPGGLLVQNYNSELLNMNDLKVV TEKKPTQEELEDLIFAMKVVKHTKSNGIALAKGKQTIGVGPGQTNRVTACKIAIEYGG ERTKGAVLASDAFFPFADCVEAAAAAGITAIIQPGGSIRDQESIDACNKYGIAMVFTG MRHFKH" misc_feature complement(10641..12182) /locus_tag="ClothDRAFT_1331" /note="bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881" /db_xref="CDD:179152" misc_feature complement(11613..12176) /locus_tag="ClothDRAFT_1331" /note="Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates 5-aminoimidazole-4-carboxamide-; Region: IMPCH; cd01421" /db_xref="CDD:29633" misc_feature complement(order(11811..11813,11880..11882,11988..11993, 12078..12080,12087..12089,12147..12149,12153..12155)) /locus_tag="ClothDRAFT_1331" /note="purine monophosphate binding site; other site" /db_xref="CDD:29633" misc_feature complement(order(11613..11615,11622..11627,11631..11639, 11661..11669,11676..11678,11775..11777,11784..11789, 11799..11801,11808..11816,11958..11960,11967..11972, 11979..11987,11994..11999,12006..12011,12018..12020)) /locus_tag="ClothDRAFT_1331" /note="dimer interface; other site" /db_xref="CDD:29633" misc_feature complement(order(11811..11813,11991..11993)) /locus_tag="ClothDRAFT_1331" /note="putative catalytic residues; other site" /db_xref="CDD:29633" misc_feature complement(10842..11783) /locus_tag="ClothDRAFT_1331" /note="AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362" /db_xref="CDD:186567" misc_feature complement(10641..>10823) /locus_tag="ClothDRAFT_1331" /note="AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362" /db_xref="CDD:186567" gene complement(12246..12875) /locus_tag="ClothDRAFT_1332" CDS complement(12246..12875) /locus_tag="ClothDRAFT_1332" /inference="protein motif:TFAM:TIGR00639" /note="TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; KEGG: geo:Geob_2776 phosphoribosylglycinamide formyltransferase" /codon_start=1 /transl_table=11 /product="phosphoribosylglycinamide formyltransferase" /protein_id="ZP_05429471.1" /db_xref="GI:256004492" /db_xref="InterPro:IPR002376" /db_xref="InterPro:IPR004607" /translation="MLRIGVLVSGGGTNLQAIIDRIESGYIKDCSIVTVVSSKPNVYA LERAKKHNISAVCIARKDYPSVHEYGEALIQHFERCEVGLIVMAGFLSILGENFVKRF ENRIINIHPSLIPAFCGKGYYGIIPHQKALEYGVKVTGATVHFVDVEADSGPIILQKA VYIRDDDTPETLQKRVMEEAEWEILPEAIKLFAEGRLEIDGRKVRIKDN" misc_feature complement(12258..12875) /locus_tag="ClothDRAFT_1332" /note="phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647" /db_xref="CDD:180182" misc_feature complement(12252..12872) /locus_tag="ClothDRAFT_1332" /note="Formyl transferase; Region: Formyl_trans_N; cl00395" /db_xref="CDD:185966" gene complement(12869..13891) /locus_tag="ClothDRAFT_1333" CDS complement(12869..13891) /locus_tag="ClothDRAFT_1333" /EC_number="6.3.3.1" /inference="protein motif:TFAM:TIGR00878" /note="KEGG: pca:Pcar_1293 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein" /codon_start=1 /transl_table=11 /product="phosphoribosylformylglycinamidine cyclo-ligase" /protein_id="ZP_05429472.1" /db_xref="GI:256004493" /db_xref="InterPro:IPR000728" /db_xref="InterPro:IPR004733" /db_xref="InterPro:IPR010918" /translation="MTTYKDAGVDVEAGYEAVRLMRNDVKRTFRPEVLTDIGGFGGLF GLNKDKYSEPVLVSGTDGVGTKLKIAFLLDKHDTVGIDCVAMCVNDIVCSGAEPLFFL DYIALGKNRPEKVAQIVKGIADGCVEAGCALIGGETAEMPGFYPEDEYDLAGFAVGIV EKSKIIDGSKIKAGDKLIGLASSGIHSNGYSLVRKILAPTAKKLAEEIKMLGTTLGEE LIKPTRLYVKTILDLKEKFEIKGIAHITGGGFIENIPRMLPQGLGVKVVRGSWPVLPI FTLLKDLGNLDEMDMYNTFNMGIGMTIAVDAEIANSVVEYLNKDKEQAYIIGEVVSDK EGLEIC" misc_feature complement(12902..13885) /locus_tag="ClothDRAFT_1333" /note="phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385" /db_xref="CDD:180049" misc_feature complement(12899..13789) /locus_tag="ClothDRAFT_1333" /note="PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine...; Region: PurM; cd02196" /db_xref="CDD:100032" misc_feature complement(order(13124..13126,13427..13429,13439..13444, 13463..13465,13469..13471,13481..13483,13574..13576, 13583..13585,13592..13594,13610..13612,13622..13624, 13688..13690,13706..13708,13712..13714,13718..13729, 13760..13774)) /locus_tag="ClothDRAFT_1333" /note="dimerization interface; other site" /db_xref="CDD:100032" misc_feature complement(order(13481..13489,13622..13624)) /locus_tag="ClothDRAFT_1333" /note="putative ATP binding site; other site" /db_xref="CDD:100032" gene complement(13984..15450) /locus_tag="ClothDRAFT_1334" CDS complement(13984..15450) /locus_tag="ClothDRAFT_1334" /inference="protein motif:TFAM:TIGR01134" /note="TIGRFAM: amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; phosphoribosyltransferase; KEGG: gbm:Gbem_2329 amidophosphoribosyltransferase" /codon_start=1 /transl_table=11 /product="amidophosphoribosyltransferase" /protein_id="ZP_05429473.1" /db_xref="GI:256004494" /db_xref="InterPro:IPR000583" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR005854" /translation="MFDVIRGKHFNYVHNLLKKDEFGFDKPKEECGVFGIYSKGNLDT ARLTYYALYALQHRGQESAGIAVNNGGTLLFHKDMGLVPEIFNEKILNSLKGKIAIGH VRYSTTGASSRENSQPMVIKYKNGQMAMAHNGNLVNAAKIREKLEEEGIIFQSTIDSE VILNLISRFRLTSNNIEEAIVKVMKEIKGAYSLVILTPNKLIGIRDPHGIRPLCIGRI DDSYVLASETCALDAVDAEYVRDVNPGEIIVIEESGMTSIQTEVPEKTALCIFEYIYF ARPDSYIDGVSVHRARIEAGRRLAREHPVEADIVFGVPDSGVSAALGYSMESGIPYDL GLIKNKYIGRTFIQPEQGQRESGVKIKLNALKEAVNGKRVVMIDDSIVRGTTSKRLVQ ILRDAGAKEVHMRISSPPYMYPCFFGVDTSSRSQLIAAECSVEEIRKMTGADSLGYLS LEGLLKTPVGAKCGFCTGCFTGKYPMEVPKDASKYSCG" misc_feature complement(13996..15378) /locus_tag="ClothDRAFT_1334" /note="amidophosphoribosyltransferase; Provisional; Region: PRK05793" /db_xref="CDD:180262" misc_feature complement(14599..15360) /locus_tag="ClothDRAFT_1334" /note="Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715" /db_xref="CDD:48479" misc_feature complement(order(14977..14979,15049..15054,15139..15141, 15274..15279,15358..15360)) /locus_tag="ClothDRAFT_1334" /note="active site" /db_xref="CDD:48479" misc_feature complement(order(14947..14952,14959..14964,14971..14973, 15088..15090,15271..15273,15292..15294,15301..15306)) /locus_tag="ClothDRAFT_1334" /note="tetramer interface; other site" /db_xref="CDD:48479" misc_feature complement(14233..14583) /locus_tag="ClothDRAFT_1334" /note="Phosphoribosyl transferase domain; Region: Pribosyltran; cl00309" /db_xref="CDD:185893" gene complement(15501..16022) /locus_tag="ClothDRAFT_1335" CDS complement(15501..16022) /locus_tag="ClothDRAFT_1335" /EC_number="4.1.1.21" /inference="protein motif:TFAM:TIGR01162" /note="KEGG: hypothetical protein ; K11808 phosphoribosylaminoimidazole carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase" /codon_start=1 /transl_table=11 /product="phosphoribosylaminoimidazole carboxylase, catalytic subunit" /protein_id="ZP_05429474.1" /db_xref="GI:256004495" /db_xref="InterPro:IPR000031" /translation="MGVTNVEKKPKVAVVMGSDSDFSVLQNCIKVLKQFDVEVSAIVC SAHRTPDKAAEFAKGAEENGFDVIIAGAGKAAHLPGVLAAFTPLPVIGVPIKSSTMDG LDSLLSIVQMPSGIPVATVAIDGAENAALLAVQILSTAYKDLRDKMKEYKKQLEKKVE EKNKALQEKIKEL" misc_feature complement(15585..15995) /locus_tag="ClothDRAFT_1335" /note="AIR carboxylase; Region: AIRC; cl00310" /db_xref="CDD:153673" gene complement(16160..17557) /locus_tag="ClothDRAFT_1336" CDS complement(16160..17557) /locus_tag="ClothDRAFT_1336" /inference="protein motif:PFAM:PF00860" /note="PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: oan:Oant_3768 xanthine/uracil/vitamin C permease" /codon_start=1 /transl_table=11 /product="Xanthine/uracil/vitamin C permease" /protein_id="ZP_05429475.1" /db_xref="GI:256004496" /db_xref="InterPro:IPR006043" /db_xref="InterPro:IPR011547" /translation="MEKFFKLKENGTNVRTEFIAGLTTFVTMAYVIFVNPNTLEASGM DKGAVFVATILAAIIGTLIMGLVANVPYAQAPGMGLNAFFAYTVVLGQGFTWQQALAL VFLCGLINILITVTRIRKMLIAAIPQSLQYAISGGIGLFITYIGIKQAHLLDFTVSSG TYTTLPNGNVVSGDIVPALADFTDPVTQLALIGLVITVVLMLLKVRGAILWGIMATTV IGLFMGITPIPELTASNFLPPSISPTFLKLDLAGLFTDPAKIPTVLATILAFSLSDTF DTIGTFLGTGRKTGIFDEEDEKALHSGKGFKSRLDKALFADSTATSIGALLGTSNTTT YVESAAGISVGGRTGLTSVFTALFFFLALFLSPIAGMVTSAATAPALIVVGILMMESL AKIKWDEFEEAVSAFFTVVVMPFTYSISNGVAAGFVFYVITKIVKGKAKEVHPILYVV VLLFILNFVFSALKL" misc_feature complement(16220..17557) /locus_tag="ClothDRAFT_1336" /note="Permease family; Region: Xan_ur_permease; cl00967" /db_xref="CDD:186286" gene complement(17852..18862) /locus_tag="ClothDRAFT_1337" CDS complement(17852..18862) /locus_tag="ClothDRAFT_1337" /inference="protein motif:PFAM:PF03547" /note="PFAM: Auxin Efflux Carrier; KEGG: apa:APP7_0949 hypothetical protein" /codon_start=1 /transl_table=11 /product="Auxin Efflux Carrier" /protein_id="ZP_05429476.1" /db_xref="GI:256004497" /db_xref="InterPro:IPR004776" /translation="MVDVQSLTEQIRILVNQISVLVIMGLIGFIAGKTRYLPDNSGSV LSRTVIKLTAPLLIFTTLAGRNFTKDILINGMWIFLLAVVFIMFSFVVGHFAGKILKL EGATANVFKMHFMFGNVIYLAFPLLRSLYGDGILIYAVFYNLANDAVLWTLGIFLVNR HNKVSVKDNLKHLVNANTIAFATGLVIMLIKSNFKGFIDGIPYIYDIGGFIANAFTPI GEATVPLSMLFIGLILSETKISSTKDLLKRYPIFVLALFKLILIPCIALFVFSFVDFV EPLVKAVIILQLSMPCATIVPALAEQYGSDYRLATENVFITTILGIVTMPFVVYLLTL AG" misc_feature complement(17882..18811) /locus_tag="ClothDRAFT_1337" /note="Membrane transport protein; Region: Mem_trans; cl09117" /db_xref="CDD:164125" gene complement(19188..21770) /locus_tag="ClothDRAFT_1338" CDS complement(19188..21770) /locus_tag="ClothDRAFT_1338" /inference="protein motif:PFAM:PF01326" /note="PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; KEGG: ppd:Ppro_0321 phosphoenolpyruvate synthase" /codon_start=1 /transl_table=11 /product="pyruvate phosphate dikinase PEP/pyruvate-binding" /protein_id="ZP_05429477.1" /db_xref="GI:256004498" /db_xref="InterPro:IPR002192" /translation="MPAFERVRSGIPSLDKVLDNIRLGDNVVIQVTCLNDFKRIVHPF VNQSIEDKRNIIYIRFSNHEPLLEYMDGLKIYQLNANRGFEAFTVEVHNIIDKEGREA FYVFDSLSDLQVAWSTDLMMGNFFCVTCPYLFELDTVALFPVLRGHHDFATIARIQET TQLFIDVYSDEKDTFIHPIKVWNRYLPDMYMPYRLNDDNELESLTGSVDLADYYNLIH NEQKRHAEQNIDSYERFFREAREAYYRGEITDWTLNKITRSMMTRDHRMADLIRKEFS PEDYFHIKERMIGTGTIGGKACGMLLARKMVANYLPQYVKYLEPQDSYYIGTDIFYSY IVENKLWKLRILQRNDKYYFEKAEELKNAISNGKFSEPIRAQFRRMLNYFGQIPIIVR SSSFLEDGFGNAFAGKYESIFCVNACDPEERLLQFEDAVRRVYASTMDRSALEYRRQR GLDKMDEQMAILVQRVSGTKFDKYYMPCAAGVGFSYSVYRWSDEFSADAGLLRLVAGL GTKAVDRTGVDYPRLVNLDNPESTILTRSSDKHRFSQRRVDVIDLQKNEVRDIDVSEL IPELPDWYVNLVCEHDYDTERMFYERGQRRNVLFVSCDGIVKKRELMKMMKDILSTLQ EHYGNPVDVEYTINFRKDGAFTVNLLQCRPMAVWESTANREIPNIEKDKVLFKVNQTF MGNSAELNIDVVVWIDSKKYHGYPYNQKSSLCSVVSKINKYYEGKNKKLMLVSPGRIG TSSPELGVPVVFSDISNFKVLCEYADIEIGFVPELSYGSHMFQDIVETEMFYVAVMGT ERSGTEVFNKEFFKNEPSVLGKIVPEAEAYEDIIKVYEFGVSKSLSLYADFKKRTAVC GVNS" misc_feature complement(19764..20894) /locus_tag="ClothDRAFT_1338" /note="Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326" /db_xref="CDD:144793" gene 22082..22375 /locus_tag="ClothDRAFT_1339" CDS 22082..22375 /locus_tag="ClothDRAFT_1339" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429478.1" /db_xref="GI:256004499" /translation="MQNSLHSHRFMGRTTFNDGHIHEYSGITSVNLNSPGHIHYMAGE TTFEDGHIHRYSLQTGPSIPVSGGHIHYYYTATSFEDGHIHYLYGYTSVYNNQ" gene 22621..23076 /locus_tag="ClothDRAFT_1340" CDS 22621..23076 /locus_tag="ClothDRAFT_1340" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429479.1" /db_xref="GI:256004500" /translation="MPSVHHSREVFHEYHDQRFVFENKKRYWEGIAKFSDYFNLYMSI FNDNLDMKYGNTRNKVISNDITFDIANKIKNLKNESRVVRENRIKDIANHILLPFDEK YNAIGKFILQTAQNIVDEANREYLLHAELIDKWPQIVIKAKNINLMDII" gene complement(23081..23188) /locus_tag="ClothDRAFT_1341" CDS complement(23081..23188) /locus_tag="ClothDRAFT_1341" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429480.1" /db_xref="GI:256004501" /translation="MLPVNTFLYAFVLIAFLAAFLTGIVLIIKELVKSH" gene complement(23410..25677) /locus_tag="ClothDRAFT_1342" CDS complement(23410..25677) /locus_tag="ClothDRAFT_1342" /inference="protein motif:PFAM:PF01915" /note="PFAM: glycoside hydrolase family 3 domain protein; KEGG: mmw:Mmwyl1_0214 glycoside hydrolase family 3 protein" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 3 domain protein" /protein_id="ZP_05429481.1" /db_xref="GI:256004502" /db_xref="InterPro:IPR001764" /db_xref="InterPro:IPR002772" /translation="MAVDIKKIIKQMTLEEKAGLCSGLDFWHTKPVERLGIPSIMMTD GPHGLRKQREDAEIADINNSVPATCFPSAAGLACSWDRELVERVGAALGEECQAENVS ILLGPGANIKRSPLCGRNFEYFSEDPYLSSELAASHIKGVQSQGVGACLKHFAANNQE HRRMTVDTIVDERTLREIYFASFENAVKKARPWVVMCAYNKLNGEYCSENRYLLTEVL KNEWMHDGFVVSDWGAVNDRVSGLDAGLDLEMPTSHGITDKKIVEAVKSGKLSENILN RAVERILKVIFMALENKKENAQYDKDAHHRLARQAAAESMVLLKNEDDVLPLKKSGTI ALIGAFVKKPRYQGSGSSHITPTRLDDIYEEIKKAGGDKVNLVYSEGYRLENDGIDEE LINEAKKAASSSDVAVVFAGLPDEYESEGFDRTHMSIPENQNRLIEAVAEVQSNIVVV LLNGSPVEMPWIDKVKSVLEAYLGGQALGGALADVLFGEVNPSGKLAETFPVKLSHNP SYLNFPGEDDRVEYKEGLFVGYRYYDTKGIEPLFPFGHGLSYTKFEYSDISVDKKDVS DNSIINVSVKVKNVGKMAGKEIVQLYVKDVKSSVRRPEKELKGFEKVFLNPGEEKTVT FTLDKRAFAYYNTQIKDWHVESGEFLILIGRSSRDIVLKESVRVNSTVKIRKRFTVNS AVEDVMSDSSAAAVLGPVLKEITDALQIDMDNAHDMMAANIKNMPLRSLVGYSQGRLS EEMLEELVDKINNVE" misc_feature complement(23698..25665) /locus_tag="ClothDRAFT_1342" /note="beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098" /db_xref="CDD:185053" misc_feature complement(24925..25593) /locus_tag="ClothDRAFT_1342" /note="Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971" /db_xref="CDD:186723" misc_feature complement(24088..24732) /locus_tag="ClothDRAFT_1342" /note="Glycosyl hydrolase family 3 C terminal domain; Region: Glyco_hydro_3_C; pfam01915" /db_xref="CDD:145207" gene complement(25744..28896) /locus_tag="ClothDRAFT_1343" CDS complement(25744..28896) /locus_tag="ClothDRAFT_1343" /inference="protein motif:PFAM:PF02018" /note="PFAM: Carbohydrate-binding CenC domain protein; type 3a cellulose-binding domain protein; von Willebrand factor type A; KEGG: eca:ECA1981 endoglucanase V" /codon_start=1 /transl_table=11 /product="Carbohydrate-binding CenC domain protein" /protein_id="ZP_05429482.1" /db_xref="GI:256004503" /db_xref="InterPro:IPR001956" /db_xref="InterPro:IPR002035" /db_xref="InterPro:IPR003305" /translation="MLRRLSYKQSALLIAVCILIQIISLASFGLNVYANSANISLEFY NGDFGASVSSISMNFRITNNGSSQISLSDIKLRYYFTDDGVSPITVFIDYANNNGRGI NNDVTYTIKDINSSGANKYIEFGFNAQAGSLEPNTSVLMRARAYQSEYKQSFTQTNDY SFCQSNNDFAAWNKVTGYLNGVLFSGTEPVMYSPTPSLSTPTPQISPTPVATPSSVPT YQATPTPSGFETPVNWDGKAVPNGDFESGSVFWSFYCDSLSGANATNLIHSEPSGNKM SKTSITNAGSNHWAIQLKHDGIVLENLKTYRLTFDAKSTVPRNIRVSLQNATSSMIEY FGKIVEVEPKMKTYTCEFTFNSTTGTNVAIVFEMGKIGTETDKAHDIVLDNVHIEKIA SPSVSPVPSEDPQGAGITASRSSVYEAELGEEVDITLSQSGEIALEGRMDTEKEIVLV LDNSGVLNSYVEDILSPLDFGIYSNHNLTVQGKDASINGSVHANDVFTSTADSISISQ TCSAASFHITSKNVNINEYKNITIPIEMPNFHSKLIDDAMRNSMVFRPEDYFLSWFPQ PMPGQEDIFIFYNLIAGRFEIFGAGTLVINSSMYFMGNVLISLTNTNNVGEGFIVADG NIIIQGQNLYPNGPNDKLYVYSIGGNIEFQTSNSTINGIAYAPGNPANPNSGKIFFSG DKNTINGSIAANELDFFAGGLVVNHTEGQFDTVEEKYIDKSTYLKLVKDAAKNFVDKF AGSKTKMAVIQYSDSANDNDFKKYDLSLPDKGAALKETIDKIKPGTSGLSNMGDGMRR AYHILNGPPPKGQISKYIVVITGSVPNRWTAVDNKKNEPKTDNGRADFIKADNESYNS LDYAKDMGRIITSKGINLVFIDFSEEDIGDVLEEIAAESGAKPLEGTDRHYYKANNFL ELLDILNNMTLKIYYDVVLDKVLYEEILPQGVLLVEAPEWISTESVPMGGVNRIKLTG EINNIPFTFTGTGYSFVVESFKIKVKFLKPGTIVFDGADSRLRYNFNYVDGAGNIHSK SVDKHFDDMTVNVTMKVDIN" sig_peptide complement(28792..28896) /locus_tag="ClothDRAFT_1343" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.834 at residue 35" misc_feature complement(28522..28776) /locus_tag="ClothDRAFT_1343" /note="Cellulose binding domain; Region: CBM_3; pfam00942" /db_xref="CDD:109977" misc_feature complement(27787..28176) /locus_tag="ClothDRAFT_1343" /note="Carbohydrate binding domain; Region: CBM_4_9; pfam02018" /db_xref="CDD:145283" misc_feature complement(26137..26739) /locus_tag="ClothDRAFT_1343" /note="Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057" /db_xref="CDD:185787" gene complement(29016..29795) /locus_tag="ClothDRAFT_1344" CDS complement(29016..29795) /locus_tag="ClothDRAFT_1344" /inference="protein motif:PFAM:PF07833" /note="PFAM: copper amine oxidase domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="copper amine oxidase domain protein" /protein_id="ZP_05429483.1" /db_xref="GI:256004504" /db_xref="InterPro:IPR012854" /translation="MKKIRVFFSYLVVFCILIIFSFTGSFSFAVQNSYASADEIKVFL NGVEIKFDVAPYIKNGRTMVPFRAIFEALGVDISWNGVNRTILATNDTTEIYIEIGKA FAYVNGYKVNLDAEAEIVGGRTFVPLRFVSENAGADVSWDGARRTVYISYVNQVRDLG EKSYFRDLEFTVDGWESEADGKILKVYGKVNLENKMLMIELYDSSRKYVSGIAEITGK DGGMNLFEVNIYLNASFNPKTILVKTLGDSNKPIKISQYNL" sig_peptide complement(29706..29795) /locus_tag="ClothDRAFT_1344" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.595 at residue 30" misc_feature complement(29346..29624) /locus_tag="ClothDRAFT_1344" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature complement(29139..29438) /locus_tag="ClothDRAFT_1344" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" gene complement(30202..30744) /locus_tag="ClothDRAFT_1345" CDS complement(30202..30744) /locus_tag="ClothDRAFT_1345" /inference="protein motif:PFAM:PF01066" /note="PFAM: CDP-alcohol phosphatidyltransferase; KEGG: dvl:Dvul_1316 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase" /codon_start=1 /transl_table=11 /product="CDP-alcohol phosphatidyltransferase" /protein_id="ZP_05429484.1" /db_xref="GI:256004505" /db_xref="InterPro:IPR000462" /translation="MNIPNILTAIRFVFIPFFGYYLYNERYTVAVILFLLAGVTDVLD GIIARKFNMVTSFGKLADPLADKLMQLTALTILTIQDIIPLPVLIIVVAKESFMIIGS ILIYKKVNFVVQADWYGKFATVVFFLAIVLTILVRSGLFANPYSDIIVNIAVIIAVGS TLFAFFMYTIEFGRLTMKSK" misc_feature complement(<30334..30744) /locus_tag="ClothDRAFT_1345" /note="CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453" /db_xref="CDD:186005" gene complement(30776..31192) /locus_tag="ClothDRAFT_1346" CDS complement(30776..31192) /locus_tag="ClothDRAFT_1346" /inference="protein motif:PFAM:PF03061" /note="PFAM: thioesterase superfamily protein; KEGG: dde:Dde_2735 4-hydroxybenzoyl-CoA thioesterase" /codon_start=1 /transl_table=11 /product="thioesterase superfamily protein" /protein_id="ZP_05429485.1" /db_xref="GI:256004506" /db_xref="InterPro:IPR006683" /db_xref="InterPro:IPR006684" /translation="MFISETEIIVRYAETDRMGIVHHSNYPIWFEAARTDFIKNLGMS YSKIEERGFMLPLIELTCRYKGAARYEDRLIVKTCIRQMSYTRVTFYYEVFKCCDNSL ITTGETVHAWTNKNLKPVNIKKHAPDIFELLNKAVL" misc_feature complement(30851..31180) /locus_tag="ClothDRAFT_1346" /note="4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active...; Region: 4HBT; cd00586" /db_xref="CDD:48031" misc_feature complement(order(30932..30943,31022..31024,31028..31030, 31100..31102)) /locus_tag="ClothDRAFT_1346" /note="active site" /db_xref="CDD:48031" gene complement(31314..32288) /locus_tag="ClothDRAFT_1347" CDS complement(31314..32288) /locus_tag="ClothDRAFT_1347" /EC_number="2.7.1.11" /inference="protein motif:TFAM:TIGR02482" /note="KEGG: tau:Tola_1457 6-phosphofructokinase; TIGRFAM: 6-phosphofructokinase; PFAM: phosphofructokinase" /codon_start=1 /transl_table=11 /product="6-phosphofructokinase" /protein_id="ZP_05429486.1" /db_xref="GI:256004507" /db_xref="InterPro:IPR000023" /db_xref="InterPro:IPR012828" /db_xref="InterPro:IPR015912" /translation="MSSVRTIGVLTSGGDAPGMNAAIRSVVRTGLYYGFKVLGIRKGF NGLINGDIEELTARSVGDIIHRGGTILQTARSPQFKTEEGLKKAMSMAKVFGIDALVV IGGDGSYRGARDISKLGLNVIGIPGTIDNDIGCTDYTIGFDTAMNTVQDAIDKIRDTA YSHERCSVLEVMGRHAGYIAVNVSISGGAEAVVLPEKPFDMDTDVIKPIIEGRNRGKK HYLVIVAEGGEGKAIEIAKEITEKTGIEARATILGHIQRGGSPTVYDRVMASQMGAKA VEVLMENKRNRVIVFKDNQIGDMDLEEALQVKKTISEDLIQLSKILAL" misc_feature complement(31323..32279) /locus_tag="ClothDRAFT_1347" /note="6-phosphofructokinase; Provisional; Region: PRK03202" /db_xref="CDD:179553" misc_feature complement(31320..32276) /locus_tag="ClothDRAFT_1347" /note="Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases...; Region: PFK; cl00204" /db_xref="CDD:185826" misc_feature complement(order(31518..31520,31527..31529,31611..31613, 31767..31775,31893..31895,31899..31901,31905..31907, 31956..31961,31965..31973,32064..32066,32157..32159, 32247..32249)) /locus_tag="ClothDRAFT_1347" /note="active site" /db_xref="CDD:29437" misc_feature complement(order(31956..31961,31965..31973,32064..32066, 32157..32159,32247..32249)) /locus_tag="ClothDRAFT_1347" /note="ADP/pyrophosphate binding site; other site" /db_xref="CDD:29437" misc_feature complement(order(31326..31328,31410..31412,31455..31457, 31476..31478,31488..31493,31638..31640,31725..31727, 31731..31736,31818..31820,31827..31829,31839..31841, 31875..31877,32094..32096,32103..32105,32118..32120, 32205..32207,32217..32219)) /locus_tag="ClothDRAFT_1347" /note="dimerization interface; other site" /db_xref="CDD:29437" misc_feature complement(order(31632..31640,31644..31646,31719..31721, 31725..31727,31818..31820,32103..32108,32115..32120, 32205..32207,32217..32219)) /locus_tag="ClothDRAFT_1347" /note="allosteric effector site; other site" /db_xref="CDD:29437" misc_feature complement(order(31518..31520,31527..31529,31545..31547, 31611..31613,31767..31775,31794..31796,31893..31895, 31899..31901,31905..31907)) /locus_tag="ClothDRAFT_1347" /note="fructose-1,6-bisphosphate binding site; other site" /db_xref="CDD:29437" gene complement(32374..32571) /locus_tag="ClothDRAFT_1348" CDS complement(32374..32571) /locus_tag="ClothDRAFT_1348" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429487.1" /db_xref="GI:256004508" /translation="MWTVVYMAQSKEIATTMQELLTSEGILVKLRPISKNHDNNDNYY EVLVPEAEVEEAHSVIIEKGY" gene complement(32593..32826) /locus_tag="ClothDRAFT_1349" CDS complement(32593..32826) /locus_tag="ClothDRAFT_1349" /inference="protein motif:PFAM:PF02081" /note="PFAM: tryptophan RNA-binding attenuator protein" /codon_start=1 /transl_table=11 /product="tryptophan RNA-binding attenuator protein" /protein_id="ZP_05429488.1" /db_xref="GI:256004509" /db_xref="InterPro:IPR000824" /translation="MDSNMERIYEDYIVIKAEENGVNIIGLTRGKDTKFHHTEKLDKG EVLIAQFTDNTSAIKIRGKARILSRHGEVYSGE" misc_feature complement(32596..32814) /locus_tag="ClothDRAFT_1349" /note="Tryptophan RNA-binding attenuator protein; Region: TrpBP; cl03437" /db_xref="CDD:186573" gene complement(32894..36439) /locus_tag="ClothDRAFT_1350" CDS complement(32894..36439) /locus_tag="ClothDRAFT_1350" /inference="protein motif:TFAM:TIGR00594" /note="KEGG: sat:SYN_00896 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein" /codon_start=1 /transl_table=11 /product="DNA polymerase III, alpha subunit" /protein_id="ZP_05429489.1" /db_xref="GI:256004510" /db_xref="InterPro:IPR003141" /db_xref="InterPro:IPR004013" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR004805" /db_xref="InterPro:IPR011708" /translation="MLQKFVHLHVHTEYSLLDGANRIKDLIRRTKELGMDSIAITDHG VMYGVVDFYKEAVNNGIKPILGCEIYTAKGSRFDKQGGWDSDPGHMVLLAKNNTGYKN LMKIVSIGFTEGFYYKPRVDMEVLEKYSEGLIAMSACLSGDIPKAILNNNYEKAKELA LKLNSIFGQDNFYLELQMNGIEEQNIVNQQLIKLSRETGIPLVATNDAHYLRREDARA HEILLCIQTGKSINDEDRMRFSSDDFYIKSPEEMISLFRNIPEAISNTVRIADMCNVE LEFNKLHLPKFDVPDGKDPFEYLRALCYEGFERIYGKDNRDEEKINRLEYELSVIKQM GYVDYFLIVSDFIRYAKEKGIMVGPGRGSAAGSFVAYCLGITNIDPLKYNLLFERFLN PERISMPDIDIDFCFERRQEVIDYVVEKYGKDRVAQIITFGTMAARAVIRDVGRALDI SYGEVDAIAKMIPFQIGMSIEKAMELNPELRQRYNDDERVKELIDTAKLLEGMPRHAS THAAGVVISREPLTEYVPLQRSEDSITTQFPMGILEELGLLKMDFLGLRTLTVIRDAV ALIKKNHNIDVKIDELQMDDPNVFKLIGEGRTAGVFQLESAGMTQFMKELQPASLEDI IAGISLYRPGPMDQIPRYLRNKNNPELVKYDHPLLENILNVTYGCMVYQEQVMQIVRD LAGYSMGRSDLVRRAMAKKKVSIMEQERKNFIYGIDDDNGNIIVKGAVRNGVDEETAN KIFDEMMDFASYAFNKSHAAAYAVIAYQTAWLKCYYPVEFIAALLNSFMGSSDKISQY VHECRKLGIEVLPPDINESDVRFTVVNGKIRFGLAAVKNVGENAVRSIIDERNINGNY KSFRNFLERVDGKDVNKRCIESLIKSGAFDSMGVYRSRLMNAYEKMMEGISSQRKKSM EGQLSIFDMALNTEDGKKDEKHQLYPEDEDIYPDIPEYSQKILLSMEKEMLGLYISGH PLSEFEKEFSEVVTLYSKDMVSDADENGEVITVEGNKGLKDGMTVTVGGIITSRKTKT TKNNNLMAFVTLEDLYGTMEIIVFPAVLERFSNLLEVENIVLIKGSISIKEEEQPKII CEEVRPLRKEDGANPLKRKVVKLYLRVDDNIDNELMESIICMLKFFGGNTPVCLYNES QKKIKVLERDCWVSLNDTVINELKLLIGEENVKVS" misc_feature complement(32900..36439) /locus_tag="ClothDRAFT_1350" /note="DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826" /db_xref="CDD:180713" misc_feature complement(36224..36421) /locus_tag="ClothDRAFT_1350" /note="DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481" /db_xref="CDD:128757" misc_feature complement(34241..35551) /locus_tag="ClothDRAFT_1350" /note="Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733" /db_xref="CDD:149024" misc_feature complement(33149..33388) /locus_tag="ClothDRAFT_1350" /note="DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli...; Region: DnaE_OBF; cd04485" /db_xref="CDD:72957" misc_feature complement(order(33161..33163,33218..33220,33224..33226, 33230..33232,33386..33388)) /locus_tag="ClothDRAFT_1350" /note="generic binding surface II; other site" /db_xref="CDD:72957" misc_feature complement(order(33176..33184,33206..33214,33233..33235, 33278..33280,33284..33292,33308..33310,33314..33325, 33365..33373)) /locus_tag="ClothDRAFT_1350" /note="generic binding surface I; other site" /db_xref="CDD:72957" gene complement(36763..38499) /locus_tag="ClothDRAFT_1351" CDS complement(36763..38499) /locus_tag="ClothDRAFT_1351" /inference="protein motif:PFAM:PF02878" /note="PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: scl:sce4837 putative phosphoglucomutase/phosphomannomutase" /codon_start=1 /transl_table=11 /product="phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I" /protein_id="ZP_05429490.1" /db_xref="GI:256004511" /db_xref="InterPro:IPR005841" /db_xref="InterPro:IPR005844" /db_xref="InterPro:IPR005845" /db_xref="InterPro:IPR005846" /db_xref="InterPro:IPR016066" /translation="MRSSALYKFWVENDYFDAETKKELLSIKDNPKEIEERFYKDLEF GTGGLRGIIGAGTNRINIYTVRKASQGLADYIKSLGLQDRGIAIAYDSRYKSPEFALE AAKVFAGNGIKAFLFDELRPTPELSFTVRHLNAAAGVVITASHNPKEYNGYKVYGEDG GQLPVEASNKVISYINKIEDITQVKVMEKDEAIEKGLLRIIGKEIDDEYISKLKTLSV NPELAAEIGKTFKIVYTPLHGTGNKPVRRILDEIGFKNVLVVKEQELPDSEFSTVKSP NPEEREAFELAIELAKKENVDLIIGTDPDCDRVGIVVRNKEGEYVPLTGNQTGCLLLE YILSQKKQRGELPENGFVVKTIVTTELARAITDAYNVELVEVLTGFKFIGEKIKQLDE FGDKKYLFGFEESYGYLAGTFARDKDAVVASMLIAEMAAYYKSRGLTLYEGLMELLEK YGYTLEGITSFTLKGKDGVEKIKSAMKNLRENRVVKFGEYEAVAVRDYLTSERYEVAT GAKEKLTLVESDVLYYELKDKAWFCIRPSGTEPKIKIYYGVTEKSMDAAKEKLKHLQD NVLSVIEPLLKD" misc_feature complement(36790..38451) /locus_tag="ClothDRAFT_1351" /note="phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150" /db_xref="CDD:185482" misc_feature complement(36802..38379) /locus_tag="ClothDRAFT_1351" /note="This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-...; Region: PGM2; cd05799" /db_xref="CDD:100092" misc_feature complement(order(36868..36870,36883..36891,36895..36897, 37279..37281,37285..37287,37291..37293,37360..37368, 37429..37431,37576..37581,37585..37587,37591..37593, 38038..38040,38062..38070,38350..38352,38359..38361, 38365..38367)) /locus_tag="ClothDRAFT_1351" /note="active site" /db_xref="CDD:100092" misc_feature complement(order(36868..36870,36883..36891,36895..36897, 37279..37281,37285..37287,37291..37293,37360..37362, 37366..37368,37429..37431,37576..37578,38068..38070, 38359..38361)) /locus_tag="ClothDRAFT_1351" /note="substrate binding site; other site" /db_xref="CDD:100092" misc_feature complement(order(37579..37581,37585..37587,37591..37593, 38068..38070)) /locus_tag="ClothDRAFT_1351" /note="metal-binding site" /db_xref="CDD:100092" gene complement(38607..41075) /locus_tag="ClothDRAFT_1352" CDS complement(38607..41075) /locus_tag="ClothDRAFT_1352" /inference="protein motif:PFAM:PF00015" /note="PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_3614 methyl-accepting chemotaxis sensory transducer" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis sensory transducer" /protein_id="ZP_05429491.1" /db_xref="GI:256004512" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /translation="MSFGPVNGIKVVIARATSKVRELTKSKLKRKSMKTLQNDTKKKE RNDTYKVYDKNRFEKIIRLSRVNKIKIGIKINLSFVITILLLSVVLGYSLLTLSNTMI QQAKESTLGLMEQTGNKIKIVLEEVDNLAMTITRDITIAPALDEINRAESEYMRARWA GIIKPYLNAYQSYRVDTISNLTLASNNGYVILGGEGTFEDVKKDYYDTVAAREFVESG AKSLWIDTHIADLFYLRRKGGNTTIALMKAVYKSTSLKSVGVLQVNLREDYLTRMLED IHIPHNGFFFIVGSKDNMIFNPQDKRDNGLLIEDLCYVNSKGQTKAELLKKTELLDLK DSEVKELLYKADTGVELDEKTLKDLRERDNYINLRILEKVRKSIDEIQTKNRQATAFG GIIEDDVIINGKKMMVTFYTIREIKGTPLEWTLISITPLENITRDVNSVAGFIVLIGV VCIIIGIMLSVLITGDISSGIGKLVKLMNKIKEGDLEVECDTTRKDEIGKLGINFVDM VENLKKLIGSIKNASNIAVESSQTVSATCQESYASIQEFSAMLDEMKNEINSQTQEIM NNDNVVNELSEQIQVIIDDFKNVSNMVTGAKKLSEAGKETVNMLKNNADEVKKTIEEF SELIGSLKRESAEISKITSTIKGISSQTNLLALNATIEAARAGEAGKSFSIVASEIKK LADQSKVSANYIESKLKNIGKTIEKTNEAVKSSGEVISGHDLAVVETINKFDNIVGFM DNVFSAITSITDYVQHIEEARCNIIKSMERLNESTKNNIRDIQNISAAMDEQVDLIKH LLSLSENLSELSVKLEQTINIFKI" misc_feature complement(39534..39701) /locus_tag="ClothDRAFT_1352" /note="Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The...; Region: HAMP; cl01054" /db_xref="CDD:154171" misc_feature complement(38682..39422) /locus_tag="ClothDRAFT_1352" /note="Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283" /db_xref="CDD:128579" misc_feature complement(38700..39278) /locus_tag="ClothDRAFT_1352" /note="Taxis toward Aspartate and Related amino acids and Homologs (TarH). The Tar chemoreceptor of Escherichia coli mediates attractant responses to aspartate, maltose, and phenol, repellent responses to Ni2+ and Co2+, and thermoresponses. These...; Region: TarH; cl00144" /db_xref="CDD:153541" gene complement(41440..42090) /locus_tag="ClothDRAFT_1353" CDS complement(41440..42090) /locus_tag="ClothDRAFT_1353" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: dar:Daro_0834 LuxR response regulator receiver" /codon_start=1 /transl_table=11 /product="two component transcriptional regulator, LuxR family" /protein_id="ZP_05429492.1" /db_xref="GI:256004513" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR013249" /translation="MDKIRVVIADDHAMVREGLKQILELEKDIAVVAQASNGEEAVKL AKECQPDVVLMDINMPGMNGLQAIEKIKAENLAVKIIVLTIHEDKEYLFKTLQMGAEG YVLKDADSTVLVEAIRSVNRGESYIQSNMTKELVREFNRVTVNEKAKKTENDLTPREL EVLELIAQGLINKEIAKRLFISEKTVKNHVSNIFKKLNVSDRTQAAIYAYKHNITK" misc_feature complement(41449..42081) /locus_tag="ClothDRAFT_1353" /note="Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197" /db_xref="CDD:32379" misc_feature complement(41731..42072) /locus_tag="ClothDRAFT_1353" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(41770..41775,41782..41784,41839..41841, 41899..41901,41923..41925,42058..42063)) /locus_tag="ClothDRAFT_1353" /note="active site" /db_xref="CDD:29071" misc_feature complement(41923..41925) /locus_tag="ClothDRAFT_1353" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(41899..41907,41911..41916)) /locus_tag="ClothDRAFT_1353" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(41767..41775) /locus_tag="ClothDRAFT_1353" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature complement(41464..41628) /locus_tag="ClothDRAFT_1353" /note="C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors...; Region: LuxR_C_like; cd06170" /db_xref="CDD:99777" misc_feature complement(order(41485..41487,41518..41532,41536..41541, 41545..41550,41572..41580,41617..41625)) /locus_tag="ClothDRAFT_1353" /note="DNA binding residues" /db_xref="CDD:99777" misc_feature complement(order(41470..41472,41479..41487,41578..41580, 41584..41586,41590..41592)) /locus_tag="ClothDRAFT_1353" /note="dimerization interface; other site" /db_xref="CDD:99777" gene complement(42083..43261) /locus_tag="ClothDRAFT_1354" CDS complement(42083..43261) /locus_tag="ClothDRAFT_1354" /EC_number="2.7.13.3" /inference="protein motif:PRIAM:2.7.13.3" /note="KEGG: hypothetical protein; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein" /codon_start=1 /transl_table=11 /product="Histidine kinase" /protein_id="ZP_05429493.1" /db_xref="GI:256004514" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR008595" /db_xref="InterPro:IPR011712" /translation="MAGYKKVDTANLDKIIKKTIEAINNSKAELFDIAENARNECVRL EKELEELKRRTSEIIKSVETLEVALYESKKRLMHVSRNYDKYSEEELREAYENADNIR VELAIKREREQYYIKRRNELEIRLKEAYKTVEKADNLISQIGISLSYLTGDLENVSLQ IEDMKQRRLLGIRIIKAQEEERQRVAREIHDGPAQSMSNIVLKAEICERLVDSDPEKA KDELRTLKSVVRDTLRDVRKIIYDLRPMSLDDLGLIPTLQRYIETCREESGIKITFKT RGTCEQLKPVVSLTVFRLVQEAVNNIKKHARADKVTINLEFLEKELKLYIADNGVGFD FDSLKSNEEDINKGFGLISMRERVELLDGKFEIDSAVGKGTRLNITVPLLPEEGVSNG " misc_feature complement(42749..43225) /locus_tag="ClothDRAFT_1354" /note="Sensor protein DegS; Region: DegS; pfam05384" /db_xref="CDD:147523" misc_feature complement(42530..42697) /locus_tag="ClothDRAFT_1354" /note="Histidine kinase; Region: HisKA_3; pfam07730" /db_xref="CDD:149021" misc_feature complement(42119..42391) /locus_tag="ClothDRAFT_1354" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature complement(order(42131..42133,42137..42142,42155..42157, 42161..42163,42209..42220,42263..42268,42272..42274, 42278..42280,42284..42286,42350..42352,42359..42361, 42371..42373)) /locus_tag="ClothDRAFT_1354" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature complement(42359..42361) /locus_tag="ClothDRAFT_1354" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature complement(order(42212..42214,42218..42220,42266..42268, 42272..42274)) /locus_tag="ClothDRAFT_1354" /note="G-X-G motif; other site" /db_xref="CDD:28956" gene 43487..44770 /locus_tag="ClothDRAFT_1355" CDS 43487..44770 /locus_tag="ClothDRAFT_1355" /inference="similar to AA sequence:KEGG:sce5027" /note="KEGG: scl:sce5027 iron-sulfur cluster-binding protein" /codon_start=1 /transl_table=11 /product="iron-sulfur cluster-binding protein" /protein_id="ZP_05429494.1" /db_xref="GI:256004515" /translation="MKSKVAIVRTKPSTVLEDYHRLMNLAEYQNYISKDVDTALKINI SWHFFYPGSSTTPWQLEGVIRALKRDGYNPELIHGCHNRTVVIDAHLGERENKQINVI KAHNLRNIHLYEGEEWIDIREAVGDLTKKFLCLNEVYPKGFSIPKRFIGENIIHLPTV KTHVFTTTTGAMKNAFGGLLNEKRHWTHPVIHETLVDLLMIQKKIHKGIFAVMDGTFA GDGPGPRCMVPHVKNVLLASADQVAIDAVAAKLMGFDPLKDCKYIRLAHDAGLGCGDV RQIEIVGDVDALNENWNFVGPYKKMTFASKCQHLIYWGPLKKPVEWTLKTILAPWSYI ASVVYHDMYWYPKNYGRVEEILNSDWGRLFANWEQLQLPADDLSVPGWEHVGDKPLKL DKETSKMIRKAFRVLGTAIREAPEFSAKKSKKACK" misc_feature <43904..44338 /locus_tag="ClothDRAFT_1355" /note="Domain of unknown function (DUF362); Region: DUF362; cl00879" /db_xref="CDD:120200" gene 44851..46074 /locus_tag="ClothDRAFT_1356" CDS 44851..46074 /locus_tag="ClothDRAFT_1356" /inference="protein motif:PFAM:PF00079" /note="PFAM: proteinase inhibitor I4 serpin; SMART: proteinase inhibitor I4 serpin; KEGG: similar to retinoic acid induced 1" /codon_start=1 /transl_table=11 /product="proteinase inhibitor I4 serpin" /protein_id="ZP_05429495.1" /db_xref="GI:256004516" /db_xref="InterPro:IPR000215" /translation="MKRTACAVLCIFVLTFLFSGCSREKKVFDELKLDTELEKKNTEF CFDIFSKLNEEDYNKNIFISPLSISTVLSMTVQGAGTTTKDGMLKALKYDGMDLDKIN ESYRYILDYLSKTDKTIELEINNSIWIREGKQIKKDFIDINKDVYNAYVTELDFSSPN AADRINKWISDSTKKKITDIIDSPIPENTAMFLINAIYFKGDWAEKFKKQDTFTAKFQ SGNGQTKEVMMMERKDTIEYGAKEDFKVVRLPYGKGTTSMYCVLPAKDVSINDFIKTL DVNKWEEIKNSISKAENVTLNIPRFKIAYGTKELRDCLIAMGMEEAFTERADFSGISE GLLFIDSVIHKAIIEVNEDGSTAAGSTVVRMIDGAAIGEPLSFIADRPFLFFITEDVT GTILFMGKLYDCEKY" sig_peptide 44851..44925 /locus_tag="ClothDRAFT_1356" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.966) with cleavage site probability 0.520 at residue 25" misc_feature 44959..46053 /locus_tag="ClothDRAFT_1356" /note="SERine Proteinase INhibitors (serpins), prokaryotic subgroup. Little information about specific functions is available for this subgroup, most likely they are inhibitory members of the serpin superfamily. In general, serpins exhibit conformational...; Region: bacterial_SERPIN; cd02049" /db_xref="CDD:29124" misc_feature 45028..46053 /locus_tag="ClothDRAFT_1356" /note="serpin-like protein; Provisional; Region: PHA02660" /db_xref="CDD:165039" misc_feature order(45910..45942,45979..45996) /locus_tag="ClothDRAFT_1356" /note="reactive center loop; other site" /db_xref="CDD:29124" gene 46297..48336 /locus_tag="ClothDRAFT_1357" CDS 46297..48336 /locus_tag="ClothDRAFT_1357" /inference="protein motif:PFAM:PF03422" /note="PFAM: Carbohydrate binding family 6; glycoside hydrolase family 43; cellulosome protein dockerin type I; SMART: cellulose binding type IV; KEGG: scl:sce3118 hypothetical protein" /codon_start=1 /transl_table=11 /product="Carbohydrate binding family 6" /protein_id="ZP_05429496.1" /db_xref="GI:256004517" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR005084" /db_xref="InterPro:IPR006584" /db_xref="InterPro:IPR006710" /translation="MPKKLKKIIKLCSMVFVIGILTLLLPEKGAADYPIFSQRFTADP AAVVYNGRLYIYCSHDSDATPGQSTYNIPDITCISTDDLKNWTDHGEVFNAKRDSRWA SVSWAPSIVYRNNKFYLYYGNGGNGIGVAVSDSPTGPFKDPLPGPLVSWNTPGVQPAQ NMWLFDPGVFVDDDGQAYMYFGGNGQNNIRVIKLGNDMISTVGSAMTMSAPRFFEAAY MHKYNGKYYFSYASDFSQGASKIEYMMSDKPTTGFQYKGVILPQPPDNYSNNNHHAIV EYKGNWYVVYHNRTVAKQRGLDPVYQRNVCIDQMFYNADGTIKQVVPTVDGLKQLKYV DPYTKNLAVTMHKESGIETEECSEGGRNVAFIENGDWIQVKGVDFGNVGPTSFEARVA SATNGGNIEIRLDSPTGTLIGTCKVEGTGDWQKWVTKTCSVSKVTGVHDLFFRFTGGS GYLFNFSWWKFNSDATPTPTPPPQPSTVPVTERSAFSKIEVEDFNDIKSSTIQKIGTP NGGSGIGYIENGDWLAYKNIDFGNGATTFKALVASTLSPNIELRLDSPTGTLIGTLKV AATGGFNAYEEQSCNISKVTGKHDLYLVFSGAVNIDWFTFGGSSGIIKRGDTNSDGKI NSTDVTALKRHLLRVTQLTGDNLANADVNGDGNVNSTDLLLLKRYILGEIENFPI" sig_peptide 46297..46392 /locus_tag="ClothDRAFT_1357" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.956) with cleavage site probability 0.665 at residue 32" misc_feature 46393..47259 /locus_tag="ClothDRAFT_1357" /note="Glycosyl hydrolase family 43; Region: GH43_AXH_1; cd09003" /db_xref="CDD:185744" misc_feature order(46423..46425,46612..46614,46789..46794,46939..46941, 47104..47106,47203..47205) /locus_tag="ClothDRAFT_1357" /note="substrate binding site; other site" /db_xref="CDD:185744" misc_feature order(46423..46425,46792..46794,46939..46941) /locus_tag="ClothDRAFT_1357" /note="active site" /db_xref="CDD:185744" misc_feature 47320..47682 /locus_tag="ClothDRAFT_1357" /note="Carbohydrate binding module (family 6); Region: CBM_6; cl02697" /db_xref="CDD:155061" misc_feature 47743..48114 /locus_tag="ClothDRAFT_1357" /note="Carbohydrate binding module (family 6); Region: CBM_6; cl02697" /db_xref="CDD:155061" misc_feature 48247..48309 /locus_tag="ClothDRAFT_1357" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 48468..49205 /locus_tag="ClothDRAFT_1358" CDS 48468..49205 /locus_tag="ClothDRAFT_1358" /inference="protein motif:PFAM:PF04542" /note="PFAM: sigma-70 region 2 domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily" /protein_id="ZP_05429497.1" /db_xref="GI:256004518" /db_xref="InterPro:IPR007627" /translation="MLFVSAIIDYAGETATHIVEKIKNGDKHLKEKFIKDYIPFILNI VSSFYSSKTGDLKSSDEYSIGLMAFNEAIEKFDVNKSKSFLKFAEMVIKKRMIDYFRK TSSIGRKEIPFSYFNSNNETEFRKKINNLDIEEEFNSYEFICELRDFSKKLESFGLSI NNLPDYMPKHKDSREMCINIAKKIVENKSIFDKLKTKKYIQMKELSKIIDVHPKTVER NRAFIICLCILFDNDYGNFKSYLNKIF" misc_feature 48504..49202 /locus_tag="ClothDRAFT_1358" /note="putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311" /db_xref="CDD:181376" misc_feature 48564..48785 /locus_tag="ClothDRAFT_1358" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" gene 49303..50748 /locus_tag="ClothDRAFT_1359" CDS 49303..50748 /locus_tag="ClothDRAFT_1359" /inference="protein motif:PFAM:PF05270" /note="PFAM: alpha-L-arabinofuranosidase B; KEGG: bgl:bglu_2g01500 rhs element Vgr protein" /codon_start=1 /transl_table=11 /product="alpha-L-arabinofuranosidase B" /protein_id="ZP_05429498.1" /db_xref="GI:256004519" /db_xref="InterPro:IPR007934" /translation="MKHKGIVLKLTKSKAIISTNDFQCYYIKRSPTIYVGKEVEFTNK DIVTKKSVLIKPALSVACFILLIACVLSLSKIINNISPKVFAYISVDINPSFEIEIDD MGNVLNLLPLNDDAKVIADKLEIDKINVSNAIDIIINEAIKSNVINENEKDFILVSST LNIKKEENSQQYQSEKEKLDIIINSLKDSIEKSGKADVYIVQADVNEREAARSKGIST GRYVLYNKYKDLENDLSLEDAKDADVNVLIKSMLDVASEERNPEESPKMTPTPTPTHT ATHTPTDAPTPKPANTPTSTPAAKPSPKTASNSASTSTPAPKPTSTPTPTLMPTPTPT PTPADKIAYGQFMKFESSNYRGYYIRVKSFSGRIDPYVNPVEDSMFKIVPGLADPSCI SFESKTYPGYYLKHENFRVILKKYEDTDLFREDATFRVVPGWADENMISFQSYNYPYR YIRHRDFELYIENIKTDLDRKDATFIGIKVD" misc_feature 50344..50730 /locus_tag="ClothDRAFT_1359" /note="Alpha-L-arabinofuranosidase B (ABFB); Region: AbfB; pfam05270" /db_xref="CDD:114019" gene 50897..52204 /locus_tag="ClothDRAFT_1360" CDS 50897..52204 /locus_tag="ClothDRAFT_1360" /inference="protein motif:TFAM:TIGR02871" /note="TIGRFAM: sporulation integral membrane protein YlbJ; PFAM: nucleoside recognition domain protein; KEGG: vfi:VF_A0618 hypothetical protein" /codon_start=1 /transl_table=11 /product="sporulation integral membrane protein YlbJ" /protein_id="ZP_05429499.1" /db_xref="GI:256004520" /db_xref="InterPro:IPR011642" /db_xref="InterPro:IPR014226" /db_xref="InterPro:IPR017871" /translation="MNLYRLTIIILIALVLAINIKSIKTIKVIYLKSLVLPLVCITFI LMLIIFSDTAVKSAGSGLNLWFNVVFPSLFPFFVASEILYRTGFIKAIGILLEPIMRP LFNVPGCGSFAFAMGITSGYPVGAKITASMREEKLLSKTESERLLSFTNNSGPLFIIG AVAVGMFKMPELGLLLLACHILASITVGILFRFYGRNNKKIKMKDDKNLWRRFKKELI YTCKQELNPGTMLGEAIRNSVNVLLSIGGFITLFSVIINILIEIGFISCLASFISPFL SPFGISREIVLAVLSGFFEMTTGTNMASKAANATLQGQLAAVSLLLGWAGLSVHFQVY SIISHTDISIKPYLFGKMLQGVFAAIYISIAMKLPFTASLTAKSVLSVITPFSDFTWY NAFIYSAQNVFISFLILLILTAISLIFHFIKHVCKTLLKRSVF" misc_feature 50993..52012 /locus_tag="ClothDRAFT_1360" /note="sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871" /db_xref="CDD:163053" misc_feature 51098..51397 /locus_tag="ClothDRAFT_1360" /note="Nucleoside recognition; Region: Gate; cl00486" /db_xref="CDD:186029" misc_feature 51620..51910 /locus_tag="ClothDRAFT_1360" /note="Nucleoside recognition; Region: Gate; cl00486" /db_xref="CDD:186029" gene complement(52227..52664) /locus_tag="ClothDRAFT_1361" CDS complement(52227..52664) /locus_tag="ClothDRAFT_1361" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429500.1" /db_xref="GI:256004521" /translation="MEMLSILETLEDLVEKSVTVPFSGKCLVDKEEILEIIKEIRLKL PDDIKQAKWIKEERQRILLEAQKEANNIIKDAENKIASLIDEHEITKKAYEQSNEIIS NAQKNAREIRLGTKEYADSILSKVEQILEETLQVIRENREELK" gene complement(52694..53173) /locus_tag="ClothDRAFT_1362" CDS complement(52694..53173) /locus_tag="ClothDRAFT_1362" /EC_number="2.7.7.3" /inference="protein motif:TFAM:TIGR01510" /note="KEGG: dol:Dole_2741 pantetheine-phosphate adenylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase" /codon_start=1 /transl_table=11 /product="pantetheine-phosphate adenylyltransferase" /protein_id="ZP_05429501.1" /db_xref="GI:256004522" /db_xref="InterPro:IPR001980" /db_xref="InterPro:IPR004820" /db_xref="InterPro:IPR004821" /translation="MSVFVYPGSFDPVTNGHMDIIQRAAKLCDKLVVAVLVNSSKNPV FTLEERVDLLKCAVKGIDNVEIESFSGLLIDFMRKKNSKVIIKGLRAVSDFEYELQMA LLNKNLDSDIETLFMMTNINYSFLSSSSVRELARHNGNIDGLVPDCIKDKIMDKFRR" misc_feature complement(52715..53173) /locus_tag="ClothDRAFT_1362" /note="Nicotinic acid mononucleotide adenylyltransferase [Coenzyme metabolism]; Region: NadD; COG1057" /db_xref="CDD:31257" misc_feature complement(52709..53161) /locus_tag="ClothDRAFT_1362" /note="Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163" /db_xref="CDD:173914" misc_feature complement(order(52796..52798,52805..52807,52817..52819, 52859..52861,52871..52873,52880..52885,52904..52906, 52910..52915,52955..52963,53051..53053,53066..53068, 53114..53116,53123..53128,53144..53158)) /locus_tag="ClothDRAFT_1362" /note="active site" /db_xref="CDD:173914" misc_feature complement(53123..53134) /locus_tag="ClothDRAFT_1362" /note="(T/H)XGH motif; other site" /db_xref="CDD:173914" gene complement(53212..53787) /locus_tag="ClothDRAFT_1363" CDS complement(53212..53787) /locus_tag="ClothDRAFT_1363" /inference="protein motif:TFAM:TIGR00095" /note="TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: gur:Gura_2499 putative methyltransferase" /codon_start=1 /transl_table=11 /product="methyltransferase" /protein_id="ZP_05429502.1" /db_xref="GI:256004523" /db_xref="InterPro:IPR002052" /db_xref="InterPro:IPR004398" /db_xref="InterPro:IPR016065" /translation="MEEFVILRVISGTAKGHKLKTIKGLATRPTSDKVKGAVFNILAA FVPGTNVLDIYAGTGSLGIEALSRGADSAVFVDKSRECFFTIKENLVHTKLESKATVI AGDVFVTLNKFSKNNKKFDIIFLDPPYGKGLVEKTLKSIAENDIIVHEGIIVAEHDIE DAVPEEVDGLERYRWEKYGNTAVSFYRLKSV" misc_feature complement(53320..53640) /locus_tag="ClothDRAFT_1363" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature complement(order(53410..53412,53470..53478,53554..53559, 53608..53628)) /locus_tag="ClothDRAFT_1363" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" gene complement(53875..55944) /locus_tag="ClothDRAFT_1364" CDS complement(53875..55944) /locus_tag="ClothDRAFT_1364" /inference="protein motif:TFAM:TIGR00643" /note="KEGG: glo:Glov_1954 ATP-dependent DNA helicase RecG; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: DEAD-like helicase ; helicase domain protein" /codon_start=1 /transl_table=11 /product="ATP-dependent DNA helicase RecG" /protein_id="ZP_05429503.1" /db_xref="GI:256004524" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR004609" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014021" /translation="MNGDMKEILKKSIKNVKGVGDARAKLFHKLGIFSIEDLITHFPY DYEDRSNIKKICQLTEGESCTFEGIIMSKVTERKIRQGLTLYQAYIKDDTGTIIATWY NQPYIKKVLTVGESYIFYGKIVRGYKTLEVQNPVYEKACKEEHKNTMKIVPVYHATAN LTQNTIRTVMQNALELVDGNLEDVLPLWVRKKYCLCDINYAFSNIHFPRNDGDIKNAR YRLVFEELFLLQLGLLSVKTVLSDGKEGIAFAPNRKEMVDFINSIGFTLTNAQKRVWE EIEKDMESNRVMNRLVQGDVGSGKTIVAALALAKAVKSGYQGAMMVPTEILAKQHYES LKDIMGKHGINVALLVGSQTKKQRSEILSKIESGEVNIVIGTHALIEEKVKFSKLGLV ITDEQHRFGVRQRAMLSNKGINPDILVMTATPIPRTLALILYGDLDISIIDELPPGRK PVKTYAVDNSMRQRINNFIKKQILEGRQAYIICPLVDESDEIEAKSALKTAEKIAKED FKDFRVGLLHGKMPAGEKEEVMQKFLKGEIDILVSTTVVEVGVNVPNATLMVVENAER FGLAQLHQLRGRVGRGPHQSYCILYNESKSQIAKERMKVMQETTDGFVISEKDLLIRG PGEFFGTRQHGLPDLKIANLYRDMEILKKSAGSGAGNFKKRSKLIYGRKSKVKGKNCR EIHRKNT" misc_feature complement(53989..55932) /locus_tag="ClothDRAFT_1364" /note="ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917" /db_xref="CDD:182836" misc_feature complement(55528..55752) /locus_tag="ClothDRAFT_1364" /note="RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a four-...; Region: RecG_wedge_OBF; cd04488" /db_xref="CDD:72960" misc_feature complement(order(55528..55530,55585..55587,55591..55593, 55597..55599,55750..55752)) /locus_tag="ClothDRAFT_1364" /note="generic binding surface II; other site" /db_xref="CDD:72960" misc_feature complement(order(55549..55551,55627..55629,55639..55641, 55690..55692,55711..55713)) /locus_tag="ClothDRAFT_1364" /note="ssDNA binding site; other site" /db_xref="CDD:72960" misc_feature complement(54673..55083) /locus_tag="ClothDRAFT_1364" /note="DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046" /db_xref="CDD:28927" misc_feature complement(55042..55056) /locus_tag="ClothDRAFT_1364" /note="ATP binding site; other site" /db_xref="CDD:28927" misc_feature complement(54751..54762) /locus_tag="ClothDRAFT_1364" /note="putative Mg++ binding site; other site" /db_xref="CDD:28927" misc_feature complement(54172..54588) /locus_tag="ClothDRAFT_1364" /note="Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079" /db_xref="CDD:28960" misc_feature complement(order(54307..54315,54388..54393,54484..54495)) /locus_tag="ClothDRAFT_1364" /note="nucleotide binding region; other site" /db_xref="CDD:28960" misc_feature complement(order(54202..54204,54211..54213,54223..54225, 54289..54291)) /locus_tag="ClothDRAFT_1364" /note="ATP-binding site; other site" /db_xref="CDD:28960" gene 56162..56350 /locus_tag="ClothDRAFT_1365" CDS 56162..56350 /locus_tag="ClothDRAFT_1365" /inference="protein motif:TFAM:TIGR00009" /note="TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: geo:Geob_2147 ribosomal protein L28" /codon_start=1 /transl_table=11 /product="ribosomal protein L28" /protein_id="ZP_05429504.1" /db_xref="GI:256004525" /db_xref="InterPro:IPR001383" /translation="MAKCDICSKDVLFGLKVSHSNRKTNRTWKPNIRRIKIIENGTSK TANVCTRCLRSNKVTRAI" misc_feature 56162..>56326 /locus_tag="ClothDRAFT_1365" /note="Ribosomal L28 family; Region: Ribosomal_L28; cl00367" /db_xref="CDD:185945" gene complement(56615..56878) /locus_tag="ClothDRAFT_1366" CDS complement(56615..56878) /locus_tag="ClothDRAFT_1366" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429505.1" /db_xref="GI:256004526" /translation="MGGFIVTIVIALIAGWLGNNIIIRQTPQDIWEACVVALPAAWIG AYMPYFNTFGPKIMDIALVPTFLFALAAAVIFKVVKKVVKQAS" gene 57009..57704 /locus_tag="ClothDRAFT_1367" CDS 57009..57704 /locus_tag="ClothDRAFT_1367" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429506.1" /db_xref="GI:256004527" /translation="MYIIFISNYKRKLVYLFAIIGLWILLFFLTGLFLNNSLTMKVTI ENYLSFSCPVKYDIDSVYVNEKIKESSIETANNFKKPRAEKFSTYESIEGGFSFKYPS AFSLNEEEFEGSEILYHVGFKNKTNTCHGFVQVWNLPYTLKEFLAKSKSASEQKYKQF EEKEVLVNSIPGIFWDYTVITQDNKSFKGNEVFLKKDDKMYRISYFVPENLWNKKESK LFESIVFSFKIKT" gene complement(57763..58968) /locus_tag="ClothDRAFT_1368" CDS complement(57763..58968) /locus_tag="ClothDRAFT_1368" /inference="protein motif:TFAM:TIGR00254" /note="KEGG: dol:Dole_1741 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein" /codon_start=1 /transl_table=11 /product="diguanylate cyclase with GAF sensor" /protein_id="ZP_05429507.1" /db_xref="GI:256004528" /db_xref="InterPro:IPR000160" /db_xref="InterPro:IPR003018" /translation="MFSIYIGFFLFAVFCWMLYKDNYENEQQNKKLFMEIANKYEQLS AAQQEIKSQNDKLKECNSKLEEANKKFMTSLAELFTLQQITQAISSIFDVRELLKSVN DIIIGVMGVSSSTIILYDENKGRLKVHTTNITNRKELIILNDNINCQKLLDALQKGEP ILENFVDMEEYPFVEGRGIHSLLCVPLITKAKKFGLVLIEHKYFNAFDDNNLRLLNII GQQVGIAMENVELYQRMHEMATIDSLTGIYNRLYFQERLREEFANAKKENYDLSLAIM DIDHFKRFNDTFGHLFGDKVLKHIAHLMKKSLRSGDIIARYGGEEFVILLPRTSVKEA YDKVERLRNIVAKTTIKDELVEASVTVSFGVSSYPEFANTESELLKTADNALYDAKES GRNCVRIPR" misc_feature complement(58558..>58911) /locus_tag="ClothDRAFT_1368" /note="IkappaB kinase complex, IKAP component [Transcription]; Region: COG5290" /db_xref="CDD:34882" misc_feature complement(58261..58692) /locus_tag="ClothDRAFT_1368" /note="GAF domain; Region: GAF; cl00853" /db_xref="CDD:154040" misc_feature complement(57775..58251) /locus_tag="ClothDRAFT_1368" /note="Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949" /db_xref="CDD:143635" misc_feature complement(order(58009..58011,58138..58140)) /locus_tag="ClothDRAFT_1368" /note="metal-binding site" /db_xref="CDD:143635" misc_feature complement(order(58006..58017,58021..58023,58087..58089, 58099..58101,58111..58116,58123..58125)) /locus_tag="ClothDRAFT_1368" /note="active site" /db_xref="CDD:143635" misc_feature complement(order(57949..57951,58033..58035)) /locus_tag="ClothDRAFT_1368" /note="I-site; other site" /db_xref="CDD:143635" gene complement(58991..59443) /locus_tag="ClothDRAFT_1369" CDS complement(58991..59443) /locus_tag="ClothDRAFT_1369" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429508.1" /db_xref="GI:256004529" /db_xref="InterPro:IPR001623" /translation="MEKVSKYELMFIRFTWIFIMVFVAHIVVCDIGMQSGQNTYPGTV IKLSFFLLIPLVNIAKYFLVRNNLFFRKKVYHTVRLVEVPLILSVIVFSGTGEWGYVM LMFLILVTSFYAEKKFSFAMVGYAFLWNIILKYLFPFPLDKKWVCGSF" gene complement(59487..60128) /locus_tag="ClothDRAFT_1370" CDS complement(59487..60128) /locus_tag="ClothDRAFT_1370" /EC_number="4.2.99.18" /inference="protein motif:TFAM:TIGR01083" /note="KEGG: sfu:Sfum_1062 endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop" /codon_start=1 /transl_table=11 /product="endonuclease III" /protein_id="ZP_05429509.1" /db_xref="GI:256004530" /db_xref="InterPro:IPR000445" /db_xref="InterPro:IPR003265" /db_xref="InterPro:IPR003651" /db_xref="InterPro:IPR004036" /db_xref="InterPro:IPR005759" /translation="MMDKKEKVKEIIKIFDELYRDAQCTLDYENPLQLLISTQLAAQC TDARVNVVTKTLFKKYKDARDFANADLKELEQDIKPTGFYHNKAKNIKETCKIIVEKF GGKVPDNMEDLLTLPGVGRKTANVILGDAFGIPGIVVDTHAKRLSNRIGLVNTDDPKK IEFELMEIVPKEKWSLFCHQLVYHGRAVCKARKPECDKCAIIDYCDYGKEHLK" misc_feature complement(59490..60080) /locus_tag="ClothDRAFT_1370" /note="Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177" /db_xref="CDD:30526" misc_feature complement(59574..60032) /locus_tag="ClothDRAFT_1370" /note="endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056" /db_xref="CDD:28938" misc_feature complement(order(59868..59870,59985..59987,59994..60002)) /locus_tag="ClothDRAFT_1370" /note="minor groove reading motif; other site" /db_xref="CDD:28938" misc_feature complement(59760..59783) /locus_tag="ClothDRAFT_1370" /note="helix-hairpin-helix signature motif; other site" /db_xref="CDD:28938" misc_feature complement(order(59583..59585,59595..59597,59751..59753)) /locus_tag="ClothDRAFT_1370" /note="substrate binding pocket; other site" /db_xref="CDD:28938" misc_feature complement(59709..59711) /locus_tag="ClothDRAFT_1370" /note="active site" /db_xref="CDD:28938" gene complement(60269..61735) /locus_tag="ClothDRAFT_1371" CDS complement(60269..61735) /locus_tag="ClothDRAFT_1371" /inference="protein motif:TFAM:TIGR02095" /note="TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase catalytic domain protein; glycosyl transferase group 1; KEGG: gur:Gura_0858 glycogen/starch synthase, ADP-glucose type" /codon_start=1 /transl_table=11 /product="glycogen/starch synthase, ADP-glucose type" /protein_id="ZP_05429510.1" /db_xref="GI:256004531" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR011835" /db_xref="InterPro:IPR013534" /translation="MRENHNLKVLFVSVEVAPFAKTGGLADVAGSLPKALVSMGYDVR IAMPKYQQIDADMRYVTDFPVDMGGRQATCIVREGEISFKADGKDLNVPVYFVDNYHY FNRGGIYCYFDDADRFAFFCKATLDMLPKIDFKPDIIHCNDWHTGPICMFLNEKYKSY PFYKNIKTMFTIHNLEYQGNFSRDVLGIMGVSDEVFVPEKVEFYGMFSFMKAGLVYAD IITTVSETYAKEIQTEKYGERLEGLLRKRSKDLYGIVNGIDYDVFNPQTDPAIYKNYN VETFELKVENKYALQKEMGLPKKDVPVIGLISRLTGQKGLNLIMDEIDEMMKEDIQFV LLGAGDEYYETGFKKIQEKYPDKVGVYIGFNAPLAQRIYAGSDMFLMPSRFEPCGLGQ LFSLRYGTIPIVRATGGLAETVIDIDKDKKNGNGFSYEEFSSKDMLKTVKRAIKFYNE KPDEWKAMVKRAMSADYSWNNSASKYSDLYMKLTKKKK" misc_feature complement(60278..61717) /locus_tag="ClothDRAFT_1371" /note="glycogen synthase; Provisional; Region: glgA; PRK00654" /db_xref="CDD:179083" misc_feature complement(60290..61714) /locus_tag="ClothDRAFT_1371" /note="This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791" /db_xref="CDD:99965" misc_feature complement(order(60563..60565,60578..60580,60629..60631, 60644..60649,60809..60817,61664..61666,61673..61675)) /locus_tag="ClothDRAFT_1371" /note="ADP-binding pocket; other site" /db_xref="CDD:99965" misc_feature complement(order(60419..60421,60494..60496,60500..60505, 60518..60520,61049..61051)) /locus_tag="ClothDRAFT_1371" /note="homodimer interface; other site" /db_xref="CDD:99965" gene complement(61876..63054) /locus_tag="ClothDRAFT_1372" CDS complement(61876..63054) /locus_tag="ClothDRAFT_1372" /inference="protein motif:PFAM:PF01966" /note="PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: gme:Gmet_0849 metal dependent phosphohydrolase" /codon_start=1 /transl_table=11 /product="metal dependent phosphohydrolase" /protein_id="ZP_05429511.1" /db_xref="GI:256004532" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /translation="MEAELDSLHEVSKVITSTFDVKVIMEHTYNELVRITRCEWYYVC FVDKESFEPAFNYEFGNQVLKEAGNIDYEQYVRNLAKSNPFSEPQIETLLREEKREIM AISLNVSDELIGAIFIGSSKTGAFSEVNLSFLKSLAGYVAIGIRNAEMFNNIYSQKQE IEALYEQAAASNEELNSYIKELDKTKEELNQKNIELMTLFDNIQYGYLQTVMCLANSI EAKDPYTRGHCQRVMEISCELARAMKLSEEEIKDLRYAAILHDIGKIGISASILNKQG KLTDEEFEEIKKHPIIAYNILKDVEFLKNGLNGILQHHERYDGKGYPYGLKGEEICIF ARIMCVADAFDAMTSDRPYRKGMDMKSALEEIKRCRGTQFDPEIADLLLMMADEGRTY " misc_feature complement(62596..63045) /locus_tag="ClothDRAFT_1372" /note="GAF domain; Region: GAF; cl00853" /db_xref="CDD:154040" misc_feature complement(61957..62388) /locus_tag="ClothDRAFT_1372" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077" /db_xref="CDD:28958" misc_feature complement(order(62029..62031,62272..62277,62371..62373)) /locus_tag="ClothDRAFT_1372" /note="Zn2+ binding site; other site" /db_xref="CDD:28958" misc_feature complement(62272..62274) /locus_tag="ClothDRAFT_1372" /note="Mg2+ binding site; other site" /db_xref="CDD:28958" gene complement(63456..64985) /locus_tag="ClothDRAFT_1373" CDS complement(63456..64985) /locus_tag="ClothDRAFT_1373" /inference="protein motif:PFAM:PF00089" /note="PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: eba:ebA2969 putative serine protease MucD" /codon_start=1 /transl_table=11 /product="peptidase S1 and S6 chymotrypsin/Hap" /protein_id="ZP_05429512.1" /db_xref="GI:256004533" /db_xref="InterPro:IPR001254" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR001940" /translation="MDELNYNGFSNEENEIKSFGELNNTTGENVDANINGDVVENAAQ YAAENIIENVDADVGENAAEGFGENVIENAAVGVADKRVENEKTYEGSFVDLKSASYY SESYTKPKKRKNSVLLQMILVAVMSSILGGSIVGGFFVFGVPALSPSVQSIFRNTNVQ NGSNDATSGVDTDYYKKVVIENNADSSVVVAIAEKVGPSVVGISVKSTTSISDFWFFT PRDTESQGSGIIIRSDGYIMTNYHVIESALNGRTNTLLPNASINVILPSDPDTPHPAT VVGTDSKTDLAVLKIEATNLPVIEFGDSDKIRVGELAVAIGNPGGLEYMGSVTVGVIS GLNRTIPITDGKELKLIQTDAAINPGNSGGALVNAEGKLIGVNTAKIGGQGYEGLGFA IPVNKAKEITDSLIQYKYVRGRPSLGIQINSGYTKEIADRYGLPEGVLVYNVEIFSAA YKAGIQKDDIITEFNGVRVKNYDELEEQKNKYKPGDKVKLKIHRDGKDITVEVTLDEQ K" misc_feature complement(64701..>64904) /locus_tag="ClothDRAFT_1373" /note="Ring-infected erythrocyte surface antigen; Provisional; Region: PTZ00341" /db_xref="CDD:173534" misc_feature complement(63789..64304) /locus_tag="ClothDRAFT_1373" /note="Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic...; Region: Tryp_SPc; cl00149" /db_xref="CDD:153545" misc_feature complement(63477..63743) /locus_tag="ClothDRAFT_1373" /note="PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind C-...; Region: PDZ_serine_protease; cd00987" /db_xref="CDD:29044" misc_feature complement(order(63558..63563,63570..63575,63723..63725, 63729..63740)) /locus_tag="ClothDRAFT_1373" /note="protein binding site; other site" /db_xref="CDD:29044" gene complement(65096..66610) /locus_tag="ClothDRAFT_1374" CDS complement(65096..66610) /locus_tag="ClothDRAFT_1374" /inference="protein motif:PFAM:PF02518" /note="PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: pmr:PMI1588 two-component system sensor kinase" /codon_start=1 /transl_table=11 /product="histidine kinase" /protein_id="ZP_05429513.1" /db_xref="GI:256004534" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /translation="MLKTLFSKIVALFIAILLVSTSITGVMLYIFLGNFASEEKEKLL SDTADSINSMLNDYLTAYYNNYNNPMFAFWEEIYRRMLDNALERESQSTGTVIWIVST EGEIGIIKGNQAVVREIVQKLTDDTGKIKLQNPAQYKDVMSGSVPMVKEIGDFYGLFK DTNVSWLTIGKPFTYNGKILGAVYLHTPVPEVQRARSSVFKFFIFAVVISIIISIVLI YIFSLKLSRPLKKINSAAKKIASGKFDERLDISSEDEIGELARSFNNMAGELQNLENM RRGFIANVSHELRTPMTSIHGFIEGILDGTIPPEKEKDYLLIVRDEIRRLNRLTTDLL DLAKMEAGEITINPVNFNINELIRRCIIKLENFITQKDIEVEANFEEEDMYVKADIDS IERVLINLMHNAVKFVQQNGKIKVSTSSYKNKVLVCVEDNGIGIDRNEIDLIWERFYK SDKSRSKEKGGAGLGLAIVRNIINDHKQEIWVESEVGKGTKFYFTLDKGSNEKA" sig_peptide complement(66533..66610) /locus_tag="ClothDRAFT_1374" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.989) with cleavage site probability 0.382 at residue 26" misc_feature complement(66365..>66511) /locus_tag="ClothDRAFT_1374" /note="Protein Kinases, catalytic domain; Region: PKc_like; cl09925" /db_xref="CDD:186871" misc_feature complement(65786..65938) /locus_tag="ClothDRAFT_1374" /note="Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The...; Region: HAMP; cl01054" /db_xref="CDD:154171" misc_feature complement(<65642..65791) /locus_tag="ClothDRAFT_1374" /note="Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-...; Region: HisKA; cd00082" /db_xref="CDD:119399" misc_feature complement(order(65645..65647,65654..65656,65666..65668, 65717..65719,65726..65728,65738..65740,65747..65749, 65759..65761,65771..65773)) /locus_tag="ClothDRAFT_1374" /note="dimer interface; other site" /db_xref="CDD:119399" misc_feature complement(65753..65755) /locus_tag="ClothDRAFT_1374" /note="phosphorylation site" /db_xref="CDD:119399" misc_feature complement(65123..65434) /locus_tag="ClothDRAFT_1374" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature complement(order(65135..65137,65141..65146,65159..65161, 65165..65167,65213..65224,65303..65308,65312..65314, 65318..65320,65324..65326,65393..65395,65402..65404, 65414..65416)) /locus_tag="ClothDRAFT_1374" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature complement(65402..65404) /locus_tag="ClothDRAFT_1374" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature complement(order(65216..65218,65222..65224,65306..65308, 65312..65314)) /locus_tag="ClothDRAFT_1374" /note="G-X-G motif; other site" /db_xref="CDD:28956" gene complement(66610..67302) /locus_tag="ClothDRAFT_1375" CDS complement(66610..67302) /locus_tag="ClothDRAFT_1375" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator" /codon_start=1 /transl_table=11 /product="two component transcriptional regulator, winged helix family" /protein_id="ZP_05429514.1" /db_xref="GI:256004535" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /translation="MYMSNKTKVLVIDDDVNICELIRLYMEKEGFEVVTVYNGSKALE VFRNEAPNIVILDIMLPGADGWQVCREIRKISNIPVIMLSAKGETFDKVLGLELGADD YLVKPFEPKELVARVKAVLRRYEHKDSDVQEIVYPNLIINKTNYTLKVNGKEMEFPPK ELELLYFLASNPNKVFTREQLIEQVWGYDFYGDSRTVDVHIKRLREKLDSEGQNWQLK TVWGVGYKFEVK" misc_feature complement(66613..67281) /locus_tag="ClothDRAFT_1375" /note="Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745" /db_xref="CDD:31088" misc_feature complement(66940..67275) /locus_tag="ClothDRAFT_1375" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(66982..66987,66994..66996,67051..67053, 67108..67110,67132..67134,67261..67266)) /locus_tag="ClothDRAFT_1375" /note="active site" /db_xref="CDD:29071" misc_feature complement(67132..67134) /locus_tag="ClothDRAFT_1375" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(67108..67116,67120..67125)) /locus_tag="ClothDRAFT_1375" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(66979..66987) /locus_tag="ClothDRAFT_1375" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature complement(66622..66903) /locus_tag="ClothDRAFT_1375" /note="Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase...; Region: trans_reg_C; cd00383" /db_xref="CDD:29475" misc_feature complement(order(66631..66633,66646..66648,66679..66684, 66706..66708,66715..66717,66769..66774,66829..66831)) /locus_tag="ClothDRAFT_1375" /note="DNA binding site" /db_xref="CDD:29475" gene complement(67362..67550) /locus_tag="ClothDRAFT_1376" CDS complement(67362..67550) /locus_tag="ClothDRAFT_1376" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429515.1" /db_xref="GI:256004536" /translation="MRQEDRQAINEIRDMIKVLIEENERLANTINELKEEQKKLQEEI KIQNIVLNSLPFRHEILN" gene 67850..68191 /locus_tag="ClothDRAFT_1377" CDS 67850..68191 /locus_tag="ClothDRAFT_1377" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429516.1" /db_xref="GI:256004537" /translation="MGQLNIVTVLVSLAVLVVIIALFAYINNKKSNSSASDNSQSSAD LTTVSDKTVNPTGNLSDDDALVAVLTAAVLASMGNRPDIKIRVTSFRRTNETSPIWNT VGRKEYISGKL" sig_peptide 67850..67924 /locus_tag="ClothDRAFT_1377" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.822) with cleavage site probability 0.820 at residue 25" gene complement(68241..69107) /locus_tag="ClothDRAFT_1378" CDS complement(68241..69107) /locus_tag="ClothDRAFT_1378" /inference="protein motif:PFAM:PF04909" /note="PFAM: amidohydrolase 2; KEGG: mxa:MXAN_1379 amidohydrolase family protein" /codon_start=1 /transl_table=11 /product="amidohydrolase 2" /protein_id="ZP_05429517.1" /db_xref="GI:256004538" /db_xref="InterPro:IPR006992" /translation="MIGNFTIVDGHVHTFSSEEVSLKVLKSFNKIYNIEFENPGTGTI EDVLNNMKNEGIDYTVMANFAPVKILHANNKWTLEEARKHPNLIPLVSFHPDMDVSFT SLLEEYISDGAKGIKLHPMAQGFDPRDERLKGLYEFCNDIAFPIVFHCGRVANARLNS FSDVETLEPLIAMYENISFVLTHMADGNVKDVLRLSRTYKNVYFDTSIVISGYPPIRE TNKPSWLDDSIPEGVINEIGAHRVVFGSDYPWGSPAWDLKRFMSMKLDDEEKKNILGE NAMKLFLNTAYN" misc_feature complement(68262..69092) /locus_tag="ClothDRAFT_1378" /note="Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618" /db_xref="CDD:33417" misc_feature complement(68265..69086) /locus_tag="ClothDRAFT_1378" /note="Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have...; Region: metallo-dependent_hydrolases; cd01292" /db_xref="CDD:30035" misc_feature complement(order(68367..68369,68559..68561,68661..68663, 69069..69071,69075..69077)) /locus_tag="ClothDRAFT_1378" /note="active site" /db_xref="CDD:30035" gene 69334..70542 /locus_tag="ClothDRAFT_1379" CDS 69334..70542 /locus_tag="ClothDRAFT_1379" /EC_number="5.4.2.1" /inference="protein motif:TFAM:TIGR02535" /note="KEGG: gsu:GSU1818 cofactor-independent phosphoglycerate mutase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein" /codon_start=1 /transl_table=11 /product="proposed homoserine kinase" /protein_id="ZP_05429518.1" /db_xref="GI:256004539" /db_xref="InterPro:IPR004456" /db_xref="InterPro:IPR006124" /db_xref="InterPro:IPR013371" /translation="MKYILILGDGMADYPISQLNNKTPLQYAKKPHIDFLAQNAEVGM VKTIPDGIPPGSDAANLSVMGYNPRVYYTGRSPLEAASMGIDLSDTDVAIRCNLVTLS EDEEYDQKTMIDYSSDEISSEEAKELIYEINRHFKNDSICFYPGISYRHCMVWKNGYT GLKLTPPHDILEKKITNYLPSGENTEILLDMMIKSYDILKDHPVNKARVSRGLRPANS IWLWGEGKKPSIPKFYDKYKLNGSVISAVDLIKGIGILAGFRNVEVEGATGNIDTNFY GKAQAALKELESGQDFVYLHIEAPDECGHRHEIENKVKSIELIDDRIVGPIIEGLEKY DDYRILILPDHPTPLSLRTHTAEPVPFLLYQKTNPKKSGVTGYDELQAAKTGIIFNDG YKLMDHFILD" misc_feature 69334..70536 /locus_tag="ClothDRAFT_1379" /note="Sulfatase; Region: Sulfatase; cl10460" /db_xref="CDD:186998" misc_feature 69334..70533 /locus_tag="ClothDRAFT_1379" /note="cofactor-independent phosphoglycerate mutase; Provisional; Region: PRK04200" /db_xref="CDD:179781" gene complement(70607..71614) /locus_tag="ClothDRAFT_1380" CDS complement(70607..71614) /locus_tag="ClothDRAFT_1380" /inference="protein motif:TFAM:TIGR00277" /note="KEGG: sde:Sde_0670 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region" /codon_start=1 /transl_table=11 /product="metal dependent phosphohydrolase" /protein_id="ZP_05429519.1" /db_xref="GI:256004540" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /translation="MRLVSVNSLKPGDELARPVFTASGKIILNSGVVLKENYIEKFKE LGINRVYIDDARFNDVEATQPIDITTRNDVVKVLKSAYTKIHNSEEIDEFAIKDAARK IVDYAREYRDRGISMLSTDVVDEYVVEHSVNVAIITAYIGNRLSYTFNQLCDLVAGAL IHDLGRENCAEEKPEHVEIGFEIMRKLRGMSLNSSKVCYEHHENFDGTGYPRKLKGTN ISDYARIVRVADYYDNVLHGRENNGVSVMPHQAFEVVLAVSGSILDPDVVQVFRDTIV FYPNGCTVKLSNGLHGVVVRQNMGSPQRPVVRLYNREGIIGDINLLEDLTLFVEDTVL T" misc_feature complement(70877..71242) /locus_tag="ClothDRAFT_1380" /note="Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077" /db_xref="CDD:28958" misc_feature complement(order(70925..70927,71126..71131,71225..71227)) /locus_tag="ClothDRAFT_1380" /note="Zn2+ binding site; other site" /db_xref="CDD:28958" misc_feature complement(71126..71128) /locus_tag="ClothDRAFT_1380" /note="Mg2+ binding site; other site" /db_xref="CDD:28958" gene complement(71821..73248) /locus_tag="ClothDRAFT_1381" CDS complement(71821..73248) /locus_tag="ClothDRAFT_1381" /inference="protein motif:PFAM:PF07508" /note="PFAM: Recombinase; Resolvase domain; KEGG: nha:Nham_3864 recombinase" /codon_start=1 /transl_table=11 /product="Recombinase" /protein_id="ZP_05429520.1" /db_xref="GI:256004541" /db_xref="InterPro:IPR006119" /db_xref="InterPro:IPR011109" /translation="MKKNGLGEIKSIYIDDNVSGSGFERRGIYELKRDVMEGKINLLV LKDLSRLGRNNAKTLLFLDFLEENGVRVVTFDGRYDSLKDNDIVGIETWFNERYILDI SRKIRANLRFKIQKGEYIGHAPFGYEKSPYEKNRLIVNEEEAGIVRRIYSLYKEGYGY SYIAGILNSEGVKSPSNGRWNPTAIRRILLNRVYTGDTVQGVSEKISFKSKKTRRLPK ERWVITENTHEPIVSKEEYEEIQRIRNNKNARPVPHKGIIHVFRGSIFCGGCGSVMFA RKRHNRPMSYICSSYAKEGRTACTSHSIREKDLCEVVLDDVAKLLDDENMVNKILQKI DLAGAAEDYQTLREKLLKQMEAKQKQQEILYQDRLENKISESLFLRMNNRLENRISEI KREIAQLDLRKSEFVTSEEKIAKLKNYITNNGITNEIVKIVINRIIVFDKGDNYLEEK WNLNLSQKEKRYIELYGAVLIEYGF" misc_feature complement(72925..>73245) /locus_tag="ClothDRAFT_1381" /note="Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788" /db_xref="CDD:155104" misc_feature complement(order(73090..73092,73099..73104)) /locus_tag="ClothDRAFT_1381" /note="catalytic residues; other site" /db_xref="CDD:58115" misc_feature complement(72517..72828) /locus_tag="ClothDRAFT_1381" /note="Recombinase; Region: Recombinase; pfam07508" /db_xref="CDD:148873" gene complement(73392..73508) /locus_tag="ClothDRAFT_1382" CDS complement(73392..73508) /locus_tag="ClothDRAFT_1382" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429521.1" /db_xref="GI:256004542" /translation="MENRDSKSRVIIKKYTGQKKAEEILSKIIQLFLSKIVR" gene complement(73599..74174) /locus_tag="ClothDRAFT_1383" CDS complement(73599..74174) /locus_tag="ClothDRAFT_1383" /inference="protein motif:TFAM:TIGR02727" /note="TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: dal:Dalk_4395 5-formyltetrahydrofolate cyclo-ligase" /codon_start=1 /transl_table=11 /product="5-formyltetrahydrofolate cyclo-ligase" /protein_id="ZP_05429522.1" /db_xref="GI:256004543" /db_xref="InterPro:IPR002698" /translation="MKDKRELRKEALNIRKGLSEEEIIEKSKLITEKLISLDGFYNSK CVMAYMDFKNEVMTRFLIEHCLNLGKIVALPLIDCVDGVKKIFPYELTNQEGCLKPGT YGILEPVKEFSRKIDPKDIDLVVVPGVAFDVKGGRIGYGAGYYDIFLREVRKDCLKIG IAFDIQVFPSIPKEEHDILMDAVVTENEIYF" misc_feature complement(73617..74165) /locus_tag="ClothDRAFT_1383" /note="5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; cl00360" /db_xref="CDD:185939" gene complement(74265..74951) /locus_tag="ClothDRAFT_1384" CDS complement(74265..74951) /locus_tag="ClothDRAFT_1384" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: conserved hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429523.1" /db_xref="GI:256004544" /translation="MNGIGDRKVCSFCGENIASDFKRCPYCGSFLDLDGNYSTDSSLD FVDTINNDVDDDSAYKFEKTINDSTSVADFTRQDVSFDQYDDYNENDFVLKEMLENKE TPLGGLNEHAGDNFGQNTGWQKPQVQQAGMQDSKPYNPDVTGRYVNNKNDNDMRKPLS NGTKVFMVTLSNLLPGIGQLFGVISAIVFINAGEDKDRKSFGAALLISSVIAFVVTIL AFAFLVLCFA" gene complement(75067..76122) /locus_tag="ClothDRAFT_1385" CDS complement(75067..76122) /locus_tag="ClothDRAFT_1385" /EC_number="2.4.2.21" /inference="protein motif:TFAM:TIGR03160" /note="KEGG: glo:Glov_3082 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase" /codon_start=1 /transl_table=11 /product="nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase" /protein_id="ZP_05429524.1" /db_xref="GI:256004545" /db_xref="InterPro:IPR003200" /db_xref="InterPro:IPR017846" /translation="MLFQTLKSIGELYKEPMDMVQRRLDSLSKPLGSLGRLEDIIKKL AGITGEVFPCVDKKAVIIMCADNGVVEEGISSCPKDVTSKVTRNFLKGITAINAFAKH TGSDIVVVDIGVDDDMDCEGIVKRKVRKGTWNIAKGPAMTRKEAIEAIEVGISIVEEL GRKGVNLLGTGEMGIGNTTTSSAVSTVLTDSKAENMVGRGAGLSDEALKRKISIVKKA IDLNRPDANDPIDVVSKVGGFDIAGLAGCFIGAAACRIPILIDGFISATAALAAVRME PKVKNFIFPSHGSAEPGSKKVMEALGFEPILNLEMRVGEGTGAALAFHIFDCAVSVYR NMGTFEDACIEQYQPQV" misc_feature complement(75097..76065) /locus_tag="ClothDRAFT_1385" /note="Phosphoribosyltransferase; Region: DBI_PRT; pfam02277" /db_xref="CDD:145435" misc_feature complement(75097..76038) /locus_tag="ClothDRAFT_1385" /note="Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439" /db_xref="CDD:143332" misc_feature complement(order(75097..75099,75112..75117,75127..75132, 75139..75141,75151..75153,75160..75162,75184..75186, 75190..75207,75211..75213,75253..75255,75820..75822, 75826..75831,75838..75846,75868..75873,75880..75882, 75895..75897,76012..76038)) /locus_tag="ClothDRAFT_1385" /note="putative dimer interface; other site" /db_xref="CDD:143332" misc_feature complement(order(75109..75111,75178..75186,75256..75258, 75331..75339,75589..75609,75868..75870,75880..75882, 75898..75900,76030..76035)) /locus_tag="ClothDRAFT_1385" /note="active site pocket" /db_xref="CDD:143332" misc_feature complement(75178..75180) /locus_tag="ClothDRAFT_1385" /note="putative cataytic base; other site" /db_xref="CDD:143332" gene complement(76312..76629) /locus_tag="ClothDRAFT_1386" CDS complement(76312..76629) /locus_tag="ClothDRAFT_1386" /inference="protein motif:PFAM:PF01386" /note="PFAM: ribosomal protein L25; KEGG: amc:MADE_02581 50S ribosomal protein L25/general stress protein Ctc" /codon_start=1 /transl_table=11 /product="ribosomal protein L25" /protein_id="ZP_05429525.1" /db_xref="GI:256004546" /db_xref="InterPro:IPR001021" /translation="MEEFELNIENRTALGTSASRKVKREGKIPGVLYQGDKSIPISLI EDEIRPIVDKNGSDVLVNVNLNGKRIKAKIHEVQRKPVSDEILHVDLMPLDGGKEDSF GVH" misc_feature complement(76354..76620) /locus_tag="ClothDRAFT_1386" /note="Ribosomal_L25_TL5_CTC: Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain. L25 is a single-domain protein, homologous to the N-terminal domain of TL5 and CTC, which each contain two domains. CTC is a known stress protein, and proteins of this...; Region: Ribosomal_L25_TL5_CTC; cd00495" /db_xref="CDD:88604" misc_feature complement(order(76354..76356,76360..76362,76366..76368, 76396..76398,76402..76407,76516..76518,76528..76530, 76531..76533,76561..76563,76567..76575,76597..76599)) /locus_tag="ClothDRAFT_1386" /note="5S rRNA interface; other site" /db_xref="CDD:88604" misc_feature complement(order(76354..76356,76405..76407,76417..76419, 76453..76455,76528..76530)) /locus_tag="ClothDRAFT_1386" /note="CTC domain interface; other site" /db_xref="CDD:88604" misc_feature complement(order(76354..76356,76378..76383,76387..76389, 76399..76401,76408..76413)) /locus_tag="ClothDRAFT_1386" /note="L16 interface; other site" /db_xref="CDD:88604" gene complement(76734..77048) /locus_tag="ClothDRAFT_1387" CDS complement(76734..77048) /locus_tag="ClothDRAFT_1387" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429526.1" /db_xref="GI:256004547" /translation="MYVTVNLLSKKPGEIKNFLESYYQKKLDMDNDVGHWIYVYYKPL QAIDLISTVIDNSDKHKMTLLIQVDKGDIHTVTYENCNDIIKALLYLYYKETGTYELE EM" gene 77362..>77760 /locus_tag="ClothDRAFT_1388" CDS 77362..>77760 /locus_tag="ClothDRAFT_1388" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429527.1" /db_xref="GI:256004548" /translation="MPMKKVLNTAKKYWMVSLIISLIFSGCSSKENNKKNNENPQAKQ QQLGSQTQEDEIPQQLESLENNIEKIILTLDGPAIELKKEKQQNQGKKGSEKEQGEQG TQDRKQSEEKNDKSKENEESEKEESKNKKDE" sig_peptide 77362..77454 /locus_tag="ClothDRAFT_1388" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.983) with cleavage site probability 0.521 at residue 31" ORIGIN 1 gcagctcgtc accactcagt accactttgt ggttccctga tgctttaaag ttgttatacg 61 cattttgtct cttctgtata aggtctcctt ttacctccaa taccccttcc gtcaagtatc 121 cctcatgact gttctgactc tgggttataa aatctcctcc aacttttata tatgatccac 181 tgtccgtcat ctttaaatat ccattactgt acgtatatgt cttgttccca ttcgcatccg 241 tattctccgt ctgcagcctg tagtctccct ctatgtaaag ctttcctcca tttatatcta 301 tagttcctcc tgattgtatc aggttcccag ttactttcaa ttcatgcccg tttaagtcta 361 aaactcctcc tccaagatac aagtctcctt catatgtctc atcatctgca agggtccatc 421 ctatagctcc gctccccgca aattttactt tgcatccgtt gtctataaac gtatttgcat 481 ttaaaggctg attaaattcc actccgtctt ccgaatagtt ccttaactca agtatgttaa 541 atcgggattc cgctgtctca aaacttactt tctgcagctt ctccccgctc aatatcgttt 601 tgtgcttccc tgacgcataa aaattatctc tatacgcgta actagactga tgttttttct 661 gtataaaatc tccctttacc tccaacactc cgtccgtaag acggcttgaa tggctataat 721 acgactgtgt cacaaaattc ccttccacac aaacataatc attctcattt gtcatgtgaa 781 ggattccatc gctaccacca tatgttattt gaccttgcgc atttacactt tccttttgaa 841 ttctataatc tccttttacg atgagcttcc caccatttat atttaaagtg ccgccggaat 901 gtataaggtt tccctctatc gtcaaattat agccgttaag attaagactt ccgctttcga 961 gatataaatc ctgatatatt ttatcttcaa ataaagccat atttgaatta acacgaattg 1021 attccctaag agttgtaact acaagtgtat tgctgggcgc tgaaacattt ccggattcat 1081 ccactgctct taccgtaaaa ctatattgcg taaaaggtaa aagaccggaa acggtacatg 1141 atgtgttttc tccatacaca gcttgtacaa ctgaagaacc attatatata ttataatagc 1201 ttacgcctgt attatcttca gccggagacc atgacatcga taccgttgaa cttgttttgg 1261 atatcaactg aagattggca ggtggcttcg gtggttcaat gtccaccggt atatcatcat 1321 aagtttcaat ttttttgtat actgattctg caaccgattc accggaatca atttgttcct 1381 tctcagcata gacttgttga atccgatatg gaaaaaaaga aggcacatca aacgtcatac 1441 caataagcaa aacaaccaaa acaattgcta cgcatctgtt aaactttctc acaattatga 1501 tccccctata taataataat taaaaaaaat gatagtattt tcctttaatt tataaactat 1561 attatatatt tcattattta aaaaatcaat atatacaatt tatataattt ttaatttcat 1621 ttaacaagat gatatatttt tttataattt tataaaaaaa ataaataaaa aatataaaaa 1681 aattaaattg tcagacaaaa aatcatataa aaagcaggga agtttatcaa accatccctg 1741 ccaaaaagta taaaaccata ctctgtttac gctaacttta tttcacaaca atattcacca 1801 gcttgcccgg aacggaaata acctttacaa catttttccc ggccgtttca gctttaatct 1861 tttcactatt caaagcccgt tcctcaacct gctcttttgt aagatccgac ggtacaacaa 1921 tcttgtctct cacctttccg tttatctgaa ccactatttc aatttcatcc ttcacaagag 1981 cagccgggtc aaatgaaggc cacttctgtt cgtgcacgct gccttccttt cctatggcgg 2041 accaaagctc ttctgttgca tgaggaataa agggagccag cattattatc aacttttcaa 2101 ttacttccct gacaagagcc ttgttcttgc tgtcatcagc cactttatcc ttgtaataat 2161 acaaggaatt aaccagctcc ataaccgcac tgattgcagt gttgaagttg aacctctggc 2221 tgatatcatc cgtaacgcgc ttcaatgtgt tgttcagcat gtaccacagc tctttatcag 2281 ccttggtaaa tgtggaagtg tcaatatttc cgccttcctt taccgcatcg gcaaactcat 2341 tgactattct ccatactctg ttgataaacc tatagcagcc ttcaactccc tggtcactcc 2401 attcaaggtc tttttccggt ggagatgcaa acagtatgaa caaccttgcc gtatcggcac 2461 cgtatttttc aattatctct tcaggactta caacattccc cagggatttt gacattttgg 2521 ctccgtcttt cagcaccatt ccctgagtaa ggaggtttgt aaacggttcg tcataatcca 2581 catatcccaa atcatagaga accttcataa ggaatctgga atacaacagg tgcagaattg 2641 catgttcaac accgcctata tactggtcaa ccggcaacca gtatcttatc ctttccttgt 2701 caaaaggagc cttgtcgtta catgggtcac aatatctaag ataataccat gaagaacata 2761 caaaggtgtc catggtatcc aattctcttc ttcccatctt accgcattta ggacaagggg 2821 ctgatatgaa tgtctcactt gtcgaaagcg gcgactctcc cacaccggaa aatttgatgt 2881 ccgtcggcaa aataaccggc aaatcctctt ccggaacagg cacagctcca caatcatcac 2941 agtagattat cggtatgggc gcaccccagt atctctgtct ggaaatcagc cagtctctga 3001 gcctgtaatt tatctttctt tttccatagc ctttttgctc gatataatca attatctttc 3061 ctatagcctc atcgcttctt acaccgtcaa attctgcgga attgacaaga taacccacct 3121 caacgaaggc ttccgtcatc ctggacgcat caagctcctg gccttccggc tgaattacaa 3181 ctttaatcgg caaattatac ttctttgcaa actcaaagtc tctctggtca tgagcaggaa 3241 cagccatgac aacaccggtt ccatactctg caagaacata attggcaagg tacaacggaa 3301 ctctgtctcc gtttaacgga ttaatgacat accttcctgt gaaaactcct tctttctcaa 3361 catcggttgc agttctgtct atttcattca aaaacatcat cttgtttata aactcgttac 3421 atacctgttc ctgttccgtt cccttaatca attctttcac cacaggatgc tcgggagcaa 3481 tcaccacgta ggtcacgcca tatatggtat caggtcttgt ggtatatacc ctgacggctt 3541 tgtccattcc gtccacttta aaatccactt cgacaccttc gctccgtcca atccagtttt 3601 gctgcataac tttaaccttg tcaggccatc ctttgagctt ttcaatatca tccagaagcc 3661 tttgagcata gtcggttatc ttaaagaacc actgttccaa atcttttttt ccgactaccg 3721 acttgcagcg ctcacaaact ccgtttacaa cctgctcgtt ggcaagaacc gtcgcacagg 3781 atgggcacca gtttacatag gcctttttct tgtacgcaag accgttttta taaagttgaa 3841 ggaacatcca ttgagtccac ttgtagtaat cgggatgaca ggtggcaacc tctctgtccc 3901 aatcataact gatgccaagt tgttttaact gccttctcat gttgtcgata ttggaccatg 3961 tccagtcatt gggatgaacc cctcttttta tggcagcatt ttcggcaggc aaaccgaaag 4021 catcccatcc catcgggtga agaacattaa aaccattcat tcttttaaat cttgccacaa 4081 catctcctat ggaataattc ctcacatgtc ccatgtgaag atttccggaa ggataaggaa 4141 acatttcaag cacataatat ttctttttgc tttcgtcttc ccggacggca aaagcttttt 4201 cctccagcca tttcttttgc cacttctttt caatatccac aaaattgtaa tacataagac 4261 aacctccaga tccaacttga aaatcgattt aattatatca aaactccaat aaacgtatcc 4321 ttaatggagt ccaattacat cttttataaa aaacacagag ggatcctgcc cctattgtct 4381 gtgcttcatt acgccgtcag cccacaacct ttcaagattg taaaattgcc tgtcctcttc 4441 atgaaaaatg tgaactacaa cttctccgta atccaataat atccacattg cgctgttata 4501 gccttcctta tgcagaagtt ctataccggc ctccaacatt ttttcttcca cttcatctgc 4561 aagagttttt atatgtgtgg tagatgtacc gctgcatatt acaaaataat ccgcaagaat 4621 tgatatttct cttatatcaa tgatatttaa atccttcgct tttttctctt cgagtatgct 4681 tacaatcttt tcggccagtt ccctggattc caacaagcct ccatcctttc atcctgaatt 4741 ttaataataa tttttaataa acatattttt atatagtata tattatttac ttaatatatc 4801 caattaaatc aacattacat gtcttaaatt ataacaccaa aacaatggtt ttgtgaataa 4861 aaacttgaca aaaatcaagg attaaagtca tctccaagta ttattataaa atcaaatcgt 4921 gaacttgggt caatttcctt tctgattctt tttatattta acaggtttcc caattcctct 4981 cccgatacgt tttctttctt ctcaataatt gcagagctga catgttttaa agagcttccg 5041 ttgcccgaac ttactacaaa accatagttt tcaagggtcg tcctgatttc ttctccaaga 5101 tttttttgtc cggtatagtt tattacatgt atgcttgcac ctttttgctg aataacaacc 5161 ggcgtctctt gaatattctc agtctcctga ggactctccg tgcttaactt ctccgcagaa 5221 gcagaagtaa ccggctccac acctggagtg ctttctgcag tgtttactgc aggtgaagga 5281 cttgtggccg caggagtagt ctccgttttc ataattcttg ccattaatgc atcgaaattg 5341 ttgtcaactt ccaccgaaga gtttttaaaa aagtaaaaat aacaacctgc tgccaaaagt 5401 aaaaacagta caacactaaa aaaaccggag cctctgtttt tctttttcct cctcaccttt 5461 ttctttgcca tgaataatca atctcccatg tgcagaaatc tatgacctgc tctccttgat 5521 tataaaattc cgggccagaa tagtgtccgg atgaataaat gctcctttgt tcattacata 5581 tcttattgtg ttgtccaaag aaagcagtat ggacctgttc aaatcacgat aagccagctc 5641 ccttacttcc tcaacccccg gaaactttct tcccggttct atgtaatctg caataaaaat 5701 tattttgtcc agcaaagtca tattctctct gccggtggta tggcattcaa tggctttaag 5761 tacatcttca tcttcaatgc catactcttc ggcggcaata accgcaccca cagggccgtg 5821 caaaagctcc ggctgcgcca acgtaatata atccacattt atatgatact ttttgcacag 5881 ctcaaacatg gcctgtccct ctatttccct tgcacaatcg tgcaaaatcc ctgccaaggc 5941 cgccttttcc acattcccgc catatttttc cgcaaggttt actgccgtgt ccataactcc 6001 aagtgaatgc tcaaatcttt taggagaaag aacactttca agttttcgtt ttatctcatc 6061 tatcgtcatc gctgattacc tctgtattag aattacttta ccattattaa agtaaaaata 6121 tttaaaaaat caaaacatct ttcaaattaa ttaaatttat ctttttaaaa ccaattacag 6181 attttaatca tttcaattac agcccattct aaatcattta agatacaatc cttctttttt 6241 tatatagttc tccaccgttt ccggaacaag gtattttatg gattttcctt cttttaccct 6301 gtttctaatc atggttgaag atatttcaat caaaggtatt tcagcctcca gtatactcgc 6361 cgaaaatctg tcctcaagat actttatccg ttccctgaag ccttctttgc cggtcccagg 6421 ccttaaagcc gcgataaact tgcagattcc aaacactttc tcgtaatctt tccatgtaag 6481 aaggtcatac aaaacatccg caccaattat gtaatacaaa tcggcaattc ctctgtattg 6541 ctcattcaaa atgcccaggg tgtctatcgt ataagtatac ccttccctgt ccacctcaat 6601 ccttgacttc tcaaaataag ggttaccctt taaagcttca cagaccatat tgtaccgatg 6661 ttcggcatcg gttactgtct gatttttttt atggggaggg ttgcccgaag gtataaaaag 6721 caccctgtcg agttcaaaag ccccccttat tatctccgcc attatcaaat ggccgttatg 6781 aataggatca aatgttcctc ccagtatgcc tattctctta acatttactt ccataaccca 6841 tttccttcac tcacaaaaat cggcttgtgc gattaagaat ctttttcaaa aaattattat 6901 agcacacaat tgccatgttt aaaataaata aatccatata aatccataca gattggaaac 6961 cttgacttaa aacttatatc atctatttgt tatccttttt cataaaaacc ataaatactc 7021 cgtcaacatc ttttacgctt gtttcaacat atcccaattt tttatataaa gctacagtat 7081 ttttactgtt taatccggta aaaatttcgt atcgtgtaca gtttttaaac acactttcaa 7141 tttccttcat taaagctttt ccaatccccc tgttttgaaa ctcaggatgt acaatcagcc 7201 ttcctatatg acaaacattg tcattatcca aatgagcacg cacagaacct ataattttcc 7261 cttccaatgt atactttaaa aacagtcttt tttcatattc ctcagtaatg ctttccaagg 7321 tctgggtcat aggaagaata ttgaaattgt tttcttccat tgccaccttt tcaaaggctt 7381 tcttttgtaa attcaatata tccggcaaat cttcttttaa tgctttttca ataatgcctt 7441 ccattttacc atcctccaaa gtttactatg taattttatt aattatacca tcagtagcaa 7501 tttgtgtcca gtttttaaca gcaatatacc atagtccttc tctattcagt tttgcactca 7561 ctcaaaatgc tatatgaaaa cttttaagat actttaaatc tccaataata tccaacagtt 7621 tatacccaat tcccttttct gtcctggtgc aaaaagaact gaaaaagatt tttctataat 7681 ttgattgtcc atacaaataa ctgcgtaagt atttacataa aaaacgtttc ataaaactca 7741 tgataattac ctgaaattat ctgataattt ataattataa atgtaaatag taaataaaaa 7801 acaagtcatt ctcaaagaag gaattttcaa aaaaatgtag aacatctcta taattagaat 7861 cgagttgata tatatttttg agttttatca acaataaatg aagaattcaa atattaaata 7921 atgaaatttt tcattatttt aaagaaacat ctgaaaatct ttcgaaaagc aatgactgtt 7981 tcatagagaa tgattgcttc catatacgtt tattccacat aaaattatta atttccagtc 8041 ggaattcagt caatatgaaa aagtcatatt tcggtactca aaaaatatat atttgctgtt 8101 ttaataaaaa aaataacttt atagtatttt ataaatgaaa agaaagtatg gtgagcaaaa 8161 attgaataaa gagttagttt cagtaatcat atgcgtttac aatggcgaaa aatatataga 8221 atcttctata aaaagcgccc ttgcgcaaac atatcaaaac atagaaataa tagtaattga 8281 tgatggttcg acggacagga cgggcgagat tgtaaaaaac tattgtcccg atgttaaata 8341 tatctatcaa gagaataaag gtgtgtcaga agccaggaat acaggactta ggcactgcag 8401 cggaaattat attgcatggt tggatgccga tgacttatat ttaccggata aaataaaaga 8461 acaggttgat tttttacaac agaataaaga tatagactgt gtatacaatg acgctttttt 8521 aatcgatgct cacgacaact tggttaaagt gcttagaagc gattatggca atttggctcc 8581 aaatgatttt ttggcacagc ttcttttcag acaaaccatt ccctgtccgc caagtacctt 8641 gtatagaaga aagtgttttg aaaacctgcg ttttattccc ggcatgaggt atgcggaaga 8701 ttattggagc agcatccaac tggcccaaag attcaaatgt ggatatttgc ctaaaatcct 8761 ctacaaatac agaaggcatg actccaacct gaccaataac aaagaaaaac aagaagaaat 8821 ggaaatcaaa gtagttaaaa gtcttggaat tgataaaata aaagatatcg tagaaaagtc 8881 ttcttatcct gagcatgaaa agcttttatt gcttggtaaa atttttatca aaatcagtga 8941 atacgaggaa gcatgtaaag ccttggaaaa aatccaagtc ccggactata ttcaggacag 9001 aaaaacgaaa tttttaaaat acttttacct gggaaatgta aactatttga caaaagaata 9061 taacaaagca aaattttgct acgaaaaatc gctccgaaca gaccccggca aagcagaagc 9121 atataacaat ttgggtgcgg cattatatca cttgtcagaa actgaggaag cacttgaaaa 9181 ttttaataaa gcactcgctt tgaaaaaaga atatctcgac cctcagaaca acttaaaaaa 9241 tataaaaaca ggcggggatt taaaaattac aatccgggag ttgagagaaa atttgatggt 9301 ttattagcaa gaaagtattt aaaggataaa aagtaagaga gcattatgct ctcctacttt 9361 tttcctatat cctttcgata gtgcatatcc tggaacttaa tctttcctac gccctcgtaa 9421 gccttcttta ttgcctcatc caaagtgttt tccatggccg taactcccag cacacgtcct 9481 cctgcggtgt aatatttgcc gttttcacgc tttgtacctg cgtggaagac cactatgttg 9541 gcatctcttt ccgcatcttc aatacctgat atctcatagc cggttttata ctcttttggg 9601 tatcctcccg aagccatgat tacgcacaca catgcactgt cattccagct tatttcaact 9661 tcatccaatc tttcatcaat aacagcttca aatatatcaa ttatgtcggt attaagcctt 9721 ggaagcacca cctgggtctc cggatctccg aatcttgcat tatactccag tactttcggg 9781 ccgtcttttg tgataataag cccaaagtac aatactccct taaacttcct gccttctttc 9841 tccatagcct caatcgtggg cttgtagatt ctttccatgc agtacctgtc aatttcctct 9901 gtatatatcc tgctgggcga aaatgttccc atacctccgg tattaagccc ctggtcattg 9961 tccaaagccc tcttgtggtc ctgggaggaa accatggtct ttatggtttt tccgtcggta 10021 aaggccagca ttgatacctc ctgacccacc aaaaactctt caattaccac cttgtttccg 10081 gcttcaccaa agaccttgtc ctccatgatg ctttgaaccg cttgtttggc ctcgtcaaaa 10141 ttctgtgcaa ttattacacc tttgcccagc gccaaaccat cggctttcac aaccaccgga 10201 tatttctgat cctgtaaata atttatggca tcggcgctgt tttcaaaaat ttcatatctg 10261 gcagtgggta tattgtattt cttcataaga tttttcgcaa aagccttgct gctttcaatc 10321 acggccgccg ccttgtttgg tccaaacgct ctgattcccg cttcctcaag agcatcaacc 10381 ataccggctg caagagggtc gtcaggcgca accactacca tgtcaatttt cttttccttc 10441 gaaaagttta caattccctc tatatccatt gcctttatcg gcacacactc tgctattgcg 10501 gaaattcctc cgttgccggg agcacagtac actttctcca ccctgggact ttgaacaatt 10561 ttccatacca atgcatgctc acggccaccg cttcctacaa ccagtacctt cattttactc 10621 ctccttaaag ttaatcatca atgcttaaaa tgtctcattc ccgtaaatac cattgcaatg 10681 ccatacttgt tgcatgcatc aatggattcc tgatccctta tcgagcctcc gggctggata 10741 attgcagtaa tgcccgcagc agctgccgcc tcaacacagt cagcaaacgg gaagaaggca 10801 tccgatgcaa gaacggctcc ttttgtcctt tccccgccat attcaatggc aatcttgcag 10861 gccgttactc tgttggtctg acccggtccg actccaatag tctgcttgcc ctttgccagc 10921 gcaataccgt tggatttggt atgctttaca actttcatgg caaaaatgag atcttccaat 10981 tcttcctggg taggtttctt ttccgtaaca actttcaaat cgttcatatt aagaagttca 11041 ctgttgtaat tttgcaccag caagcctccc ggcactttct tcatgtcata agttcccttt 11101 ggaattttag ccgaaatgtc ctcaagctga agcagtctta tgttcttctt ctgggtaaga 11161 atttttaatg ccccttcagt aaaggacggt gcgataacta tctcaacaaa aatcttgttt 11221 atttcctcgg ccgttttttc gtcaatttcc ctgttggccg caataatacc gccgaatatg 11281 gacacaggat ccgcctcata tgcctttata taagcatcat atatatttga agcacttgcc 11341 acaccacacg gatttgcatg tttcaccgcc accacggtgg gttcgtcaaa ctcttttatg 11401 atttctatgg caccgtttgc atcatttata ttgttatagg aaagttcctt tccgtgcagc 11461 tgttttgcag ccgttataca gccgacattc gctcccactt ctttatagaa caccgctttt 11521 tggtggggat tttcaccata tctcatatcc tggacctttt caaaggtcag agaaagggtt 11581 tgagggaact cgtcttctcc gatttgctct cttaaatact ttgcaattaa agtatcataa 11641 tgacttgtat gttcaaacac tttatatgcc agcttgaact tggttttcaa tgatacatcc 11701 ttcgtagtct taagctcttc caatacggca gcatagtctg aagggtcaac aattacaacc 11761 acgtcctgat aattctttgc cgcagctcta atcattgtag gtccgcctat atcaatattt 11821 tcaattgcct ccgaaaggtc aacgttttct tttaatatcg tctgcttgaa cggataaaga 11881 ttgatgatta ccatgtctat tgtctctatg ttaagctctt tcagctgtct catatgttcc 11941 tcattgcttc ttattgcaag aattcccgca tgaactttgg gatgaagggt ttttaccctt 12001 ccgtcaagac attccggaaa accggtaaca tccgatatgt ttattacctt tataccggca 12061 tcactcaatg tctttgcagt accaccggtg gaaataatat caactcccat gctttgaagt 12121 tcacgggcca tttcaacaat tcccgtcttg tcggatacac ttatcagtgc acgctttatc 12181 atactatcac tcctttttta gtttatagca aaacttaagc aaaattctgc aaactttctg 12241 tcaacttaat tatccttaat tctaactttc cttccatcga tttcaagcct tccttcggca 12301 aaaagcttta tggcctcagg gagaatttcc cactccgcct cctccatcac cctcttctgg 12361 agagtttcgg gagtgtcatc gtcccttatg tacacagctt tctgcagaat aataggtccg 12421 ctgtcggctt caacgtcaac aaaatggacc gttgctccgg tcactttgac cccgtattcc 12481 agcgccttct gatgaggaat tatgccataa tagcctttgc cgcagaaagc aggtatcaaa 12541 gaaggatgaa tgttgattat cctgttttca aaccgtttta caaagttttc tcccagtatg 12601 gacaaaaatc ccgccataac aataaggccc acttcgcagc gttcaaaatg ctgtatcagc 12661 gcttccccgt attcatgcac cgaaggataa tcttttctgg caatgcaaac cgccgaaata 12721 ttgtgttttt tggctctttc aagggcatac acattgggtt tgctcgacac aacggtaaca 12781 atcgagcagt cctttatata gccgctttca attctatcaa ttatagcctg aagatttgtt 12841 ccccctccgg aaaccaacac accaattctt aacatatttc aagcccttcc ttgtctgata 12901 caacttctcc gattatgtaa gcctgctctt tatccttgtt caaatactcc acaacactgt 12961 ttgcaatttc agcatccacg gcaattgtca tacctattcc catgttaaag gtattgtaca 13021 tatccatttc gtcaaggttt ccaagatctt ttaagagagt gaatatcgga agtacaggcc 13081 agctacccct gactactttg actcccaaac cttgaggcag cattctcggt atgttttcaa 13141 tgaatcctcc gcctgtaata tgggcaattc ccttgatttc aaacttttct ttcaaatcca 13201 ggatcgtctt gacatacagt cttgtgggct ttataagctc ttcacccaaa gtggttccaa 13261 gcatcttaat ctcttccgca agttttttcg cagtaggcgc caaaatcttc cttacaaggg 13321 aatatccatt gctgtgaata cctgatgacg caagtcctat taatttgtcc cccgccttga 13381 ttttactgcc gtctataatc ttgctttttt ccactattcc gaccgcaaat ccggccaaat 13441 catattcatc ctcaggataa aatcccggca tttccgccgt ttctcctccg attagggcac 13501 atcctgcttc aacacatccg tcggctatac ctttcacaat ctgagccact ttttcgggac 13561 ggtttttgcc caaggctata tagtcgagga aaaacagagg ttccgcacca ctgcacacaa 13621 tatcatttac acacatcgcc acacagtcaa taccaacggt atcatgcttg tccagcagga 13681 aagcaatttt cagttttgta cccacgccat cagttcctga tacaagaacg ggttccgaat 13741 atttatcttt gtttaagcca aacaatccac caaagccacc tatatcagta agcacctcag 13801 gcctgaatgt cctttttaca tcatttctca taagcctgac cgcttcataa ccggcttcca 13861 catcaacacc cgcatcttta tatgtagtca tcaaagtacc tcctaattac aaatgaaata 13921 aattatatat aatagatttc agcaattatt ttagcaatta acaaatatta tgtacaacta 13981 tcattacccg caactatact tgctggcatc tttaggtact tccatcggat atttgcctgt 14041 gaagcatccg gtacaaaaac cgcattttgc tcccaccggc gttttcaaga gcccttcgag 14101 acttaagtac ccaaggctgt ccgcacctgt catctttctg atttcctcaa cggaacattc 14161 cgccgcaata agctgggacc tgctcgatgt gtcaactcca aagaaacatg gatacatata 14221 aggcggagag ctgattctca tatgaacttc cttcgcaccg gcatccctta aaatttgaac 14281 aagtctcttg ctggtagtac ctctgactat tgagtcatct atcataacaa cccttttacc 14341 gttaacggct tccttcaaag cattaagctt aattttcact ccgctttccc tctgtccctg 14401 ttccggctga ataaaggttc ttccgatata tttgtttttt ataagtccca aatcataagg 14461 tattcccgac tccatggaat aacccagtgc cgcggataca cccgaatccg gaactccgaa 14521 aacaatgtcg gcttccacag gatgctcccg ggcaagcctt cttccggcct caattctcgc 14581 tctgtgaaca cttacaccgt caatatagct gtcgggtctt gcaaagtaaa tatactcaaa 14641 aatgcaaagt gccgtctttt ccggaacttc cgtttgtatt gaagtcattc cgctctcttc 14701 aataacgata atctctccgg gatttacatc tcttacatat tcggcatcta ctgcatcaag 14761 agcgcaagtc tctgaagcaa gaacatagga atcatctata cggccgatgc aaagcggtct 14821 tataccgtga gggtctctga taccaataag cttgtttggt gtgagaataa ccagcgaata 14881 cgcacctttt atctccttca ttaccttgac aatggcctct tcaatattgt tgctggtcag 14941 cctgaatctt gaaatcaaat tcaaaattac ctcggaatct atagtcgact ggaatataat 15001 accctcttcc tcaagttttt ctcttatctt tgcggcatta acaagattgc cgttatgagc 15061 catggccatc tgtccgttct tgtactttat aaccataggc tgggagtttt ccctgctgct 15121 cgcaccggta gtcgaatatc tcacatgtcc tattgcaatt ttgcctttga gactgtttaa 15181 aattttttca ttgaaaatct cgggaacaag ccccatgtcc ttgtgaaaga gaagtgtccc 15241 accattgttg acggcaattc ccgcactttc ctgtcctctg tgctgaagcg cataaagggc 15301 ataataagtc agacgtgcgg tatccaaatt acctttactg taaataccga aaactccaca 15361 ctcttctttc ggcttgtcaa acccaaactc atcttttttc aacaaattgt gtacgtaatt 15421 aaaatgcttt ccccttatta catcaaacat agcttttact ccttatatca gtttggtata 15481 atttacctga atatgagttg ttaaagttct tttatctttt cctgaagagc tttgttcttc 15541 tcttcaacct ttttctcaag ctgcttttta tattccttca ttttgtccct gagatccttg 15601 taagcagttg acaatatctg aaccgcaagc aaagcagcat tttccgcacc gtctatcgca 15661 accgtggcaa ccggaattcc tgaaggcatt tgaactatag acagcagtga atcaagcccg 15721 tccattgtag atgatttaat tggcacaccg ataaccggaa ggggcgtaaa tgctgccaga 15781 actcccggca aatgagccgc ttttcccgca ccggctatta taacatcaaa accgttttct 15841 tcggcacctt tagcgaactc agccgctttg tcgggtgtcc tgtgggccga gcaaactatt 15901 gccgaaacct ccacatcaaa ctgctttaag accttgatgc agttctgtaa aactgaaaaa 15961 tcggaatcac tccccattac aacagcaact tttggttttt tttcaacatt ggtcacaccc 16021 atagttcaac ctccccaaaa atttgaaata tagttgtatt gttgaattat atattcttac 16081 ataaatatca cgtaccaaaa ttagccatca gaaaacataa aagtctgatc caatcggatc 16141 aaacttttat gtgcaatatt catagcttta aagcggaaaa tacgaaattc agtataaaaa 16201 gcaacactac tacataaagg attggatgta cctcttttgc tttgcctttt acaatttttg 16261 ttattacata gaatacaaaa cctgccgcaa ctccgtttga aatgctgtat gtaaaaggca 16321 ttacaacaac cgtgaaaaat gctgaaaccg cttcttcaaa ctcatcccat tttatcttgg 16381 caagggactc catcatcaaa atacccacta caataagtgc cggagcagtt gcggcggatg 16441 ttaccatacc ggcaatcggt gacaggaaca atgccaggaa gaaaaacaat gcggtgaaaa 16501 ccgatgtaag accggttctt cctcccacgc tgattcctgc agcactttca acataagtgg 16561 tagtattgct tgtacctaaa agtgctccta ttgacgttgc agttgagtct gcaaacaaag 16621 ccttatccag tcttgattta aatcctttgc ctgagtgaag tgctttttcg tcttcttcgt 16681 caaaaattcc ggtctttctg ccagttccca ggaatgttcc tattgtatca aaagtatccg 16741 ataggctgaa ggcaagtatc gtggccaaga ctgtcggtat cttcgccgga tcagtgaaaa 16801 gtcccgccaa atcaagcttt aagaaagtcg gtgatattga cgggggcaaa aagtttgacg 16861 ctgtcagttc cggaataggt gttatgccca taaacagtcc aatcactgtg gttgccataa 16921 tcccccaaag tattgctccc ctgactttta aaagcattaa aacaaccgta attacaagcc 16981 cgattaatgc caattgagtt accggatcgg taaagtcggc aagagccgga acaatgtctc 17041 ctgaaaccac gtttccattg ggaagtgtag tataagtgcc gctgctgact gtaaaatcca 17101 ataaatgcgc ctgtttaatt cctatgtatg ttataaacag gcctattcct ccgcttatag 17161 catactggag ggattgaggt attgccgcta tcagcatctt tctaattctt gtgacggtaa 17221 taagtatgtt tatcagtccg caaagaaaaa ccagtgccaa agcctgctgc caggtaaatc 17281 cctgtcccaa aacaacggtg tatgcaaaga atgcgttaag ccccattccc ggagcttggg 17341 catacggaac gtttgccacc aatcccatta tcaatgtacc gattattgct gcaagtattg 17401 ttgcaacaaa cacagcacct ttgtccattc ccgaagcttc cagggtattg ggattgacaa 17461 aaataacata tgccatcgtt acgaaagtag ttaaacctgc tataaattcc gtcctgacat 17521 ttgtgccgtt ttccttgagc ttaaagaact tttccataag actcctcctt catcctttcg 17581 gacttaataa aagtttgaaa taaaaatggg ctggcagaac caaccctcca aaccgataca 17641 acaaaacgat gtccttaacc gccaaaactt ctgcttcttc gaacaaaaga acattttcat 17701 ccttgtccga actaaacctg ccttttacat aaataatact atcaaaacaa agtacggctt 17761 gtcaacgaaa gttatcaaaa aatacgaaca ttattttaaa tttttgaggt taatattcgt 17821 ttttttacga aattataagc ttacataata tttatccggc caaagtcagc aaataaacca 17881 caaagggcat tgtcacaatc cccagtattg tcgttataaa cacgttttcg gtggcgagcc 17941 tgtaatcaga accgtactgc tccgccaaag cgggaacaat tgtggcacac ggcatcgaaa 18001 gctgcagtat gattaccgct ttcacaagag gttctacaaa atccacaaaa gaaaatacga 18061 acaaagcaat acacggaatc aggataagtt taaacaaagc taaaacaaat atagggtatc 18121 tttttaataa atccttcgta ctgcttattt tcgtttcaga caatatcagg cctataaaaa 18181 gcattgacaa aggaaccgta gcctctccta taggagtaaa tgcattggct atgaatccgc 18241 ctatatcata aatgtatgga atgccgtcta taaatccttt gaaatttgac tttatcagca 18301 taataacaag acctgttgca aaagctatgg tattggcatt tacaagatgc tttaaattat 18361 ctttcacact caccttgttg tgcctgttta cgagaaaaat tcccaaagtc cataaaacag 18421 cgtcattcgc caaattgtaa aacacagcat agattaaaat accgtctcca taaagtgacc 18481 ttaaaagggg aaaagccaga taaattacgt ttccaaacat gaaatgcatt ttaaatacgt 18541 tcgcagttgc cccttcaagt tttaatatct ttccggcaaa atgccccact acaaaggaaa 18601 acattataaa tactaccgcc aaaaggaata tccacattcc gtttatcaga atgtctttag 18661 taaaatttcg tcccgccagg gtcgtaaaaa tcaggagcgg tgccgtaagc tttattaccg 18721 ttcttgaaag cactgatccc gaattatccg gaagataacg ggttttacct gcaataaacc 18781 ctatgagtcc cattatcact aaaacagaaa tttgattgac taaaattcgt atttgctccg 18841 taaggctttg aacatcgacc atttttataa ctcccgcaaa atatttgtca aactgccttg 18901 agatactccg tttagccgta tccccatata tcgacatttt tttagcagcg tgaccgagtg 18961 atatgataac atattagcag gagcttttca acaattataa tttgatatgt caattgtaat 19021 ttggatatgt tcagtctaat gcaatgactt cgtttttttt aacctgtcta atatccgccg 19081 attttttaaa gctttacaca tcctggtttc catccggttt caatgccatt gaatgaaaaa 19141 caaacatctt ttttattttt aaacttaacc gtaatacttt gtgacagtta agaatttaca 19201 ccgcaaactg cagttctttt cttaaaatca gcatagaggc ttagtgattt tgaaacacca 19261 aattcatata ctttgatgat atcttcatat gcttcagctt caggaacaat cttacccaga 19321 accgaaggct catttttgaa aaactctttg ttaaatactt cggtaccgct tcgctcggtg 19381 cccattaccg ccacataaaa catttccgtt tcaactatgt cctgaaacat atgactgcca 19441 taagacaact caggaacaaa tccaatttca atatccgcat actcgcatag gactttaaaa 19501 ttggatatat ccgaaaacac aaccggaact cccaattcag gggatgaagt cccaattcgc 19561 cccgggctta caagcatcag tttcttattc tttccttcat aatatttgtt aattttagag 19621 actacactgc acaaagagct tttctgatta taaggataac catgatactt ttttgagtca 19681 atccacacaa ccacatcaat gttcaactct gcggaattcc ccataaaagt ctgattaact 19741 ttaaacagaa ctttatcttt ttcaatattc ggaatttccc gattggcagt actctcccat 19801 acagccatgg gcctgcactg aagaagattt acggtaaatg ctccgtcctt tctgaaatta 19861 attgtgtatt ccacatccac aggatttccg taatgctcct gaagagtgga aagaatatct 19921 ttcatcattt tcataagctc tcttttctta acaatcccgt cacacgaaac aaaaagaaca 19981 tttcgtctct gtcctctttc ataaaacatt ctctcagtat cataatcatg ctcacagaca 20041 agattcacat accaatccgg aagctcagga atcagttcac ttacatcaat atctcttact 20101 tcatttttct gtaaatcaat aacatccact cttcgctgtg aaaaacgatg tttatcactc 20161 gacctcgtta aaatggtact ttcaggatta tccaggttta ccagccgggg ataatcgaca 20221 cccgttctgt ccaccgcctt tgtacccaga cctgcaacca aacgcagaag tcccgcatct 20281 gcactaaatt catcactcca gcggtataca ctataggaaa aaccaactcc cgcagcacat 20341 ggcatataat atttgtcaaa tttcgttccg ctgacacgct gcaccaaaat cgccatttgc 20401 tcgtccattt tatcaagtcc ccgttgtctg cggtactcca aagcagacct gtccatcgtg 20461 cttgcatata ccctgcgcac cgcgtcttca aattgcaaaa gcctttcttc cggatcgcat 20521 gcgtttacgc agaaaatcga ctcgtatttt cccgcaaaag catttccaaa tccgtcttcc 20581 aggaaactgc tcgaacgcac aatgatagga atttgtccga aatagttcag cattcttctg 20641 aattgcgccc taatgggctc ggaaaattta ccgtttgata tcgcattttt cagttcttcc 20701 gccttttcaa aataatactt gtcattacgc tgtaaaatac gtaatttcca gagtttgttt 20761 tccacgatat atgaataaaa gatatcagtt ccgatataat aggaatcctg aggctccaaa 20821 tactttacat actgaggcag gtagtttgca accatttttc ttgccaaaag cataccacat 20881 gcctttcccc caattgttcc ggtaccgatc attctttctt tgatatggaa ataatcctca 20941 ggactgaatt cttttcttat caaatcagcc attctgtggt cgcgggtcat catgctgcgg 21001 gttattttat taagagtcca gtctgtaatt tcacccctgt aataagcttc cctggcctcc 21061 ctgaaaaacc tttcataact gtcaatattc tgctcggcgt gcctcttttg ctcattatga 21121 ataagattgt agtaatctgc caaatccaca ctgccggtca gggattccag ctcgttgtcg 21181 tcattcagcc tgtaaggcat atacatgtca ggcaaatagc ggttccaaac tttaatagga 21241 tgtataaacg tatctttttc gtccgaatac acatcaataa acagctgtgt tgtctcctga 21301 atacgggcaa ttgttgcaaa atcgtgatgc cctctcagta caggaaacaa tgccacagtg 21361 tcaagttcaa acaaataggg gcaggttaca caaaagaaat ttcccatcat caagtctgtg 21421 gaccaggcaa cctgcaggtc ggaaagggaa tcaaacacat aaaatgcctc ccttccctcc 21481 ttatcaatta tattgtggac ctcaaccgta aaggcctcaa accctcgatt ggcattcagc 21541 tgataaattt tcagcccgtc catgtattcc agtaaaggtt catggttgga aaaacggata 21601 taaataatat ttcttttgtc ctcaatggat tgatttacaa agggatgcac tattctttta 21661 aaatcattca aacaagttac ctgtatgacc acattatctc caagtcttat gttgtcaaga 21721 accttgtcca aactcggtat acctgatcta accctttcaa aagccggcat atctttcacc 21781 tatatagctt taactatatt tgttcctttc ttccagatta ttatcaaatg ggtagaaatc 21841 tattttaaag ctaaggtaat tctatatatt cattataaca ttttttataa atttattata 21901 atataacgct cagaaaaaat accaagaaat ctcataaaaa attgaatttt ccccattcca 21961 ttgagcatct cgctacaatg gttaacttaa gggtatttac tgcttaatgc accataaaat 22021 acgttattat agaagtaaca ccctctacat agttaacata atatgtattg aggtgattat 22081 tatgcaaaac agtttgcaca gtcatagatt tatgggaaga actactttta atgacggcca 22141 tattcatgaa tattcaggta taaccagtgt aaacctcaac agtcccggtc acatacacta 22201 catggctggc gaaaccacct tcgaagacgg tcatatacat cgttatagcc tacaaacagg 22261 tcccagtata cccgttagcg gtggacatat acactattac tacactgcaa cctcttttga 22321 ggatggtcat attcactatt tatatgggta tacaagcgtt tataataatc aataagacgg 22381 cttaaaactc gattattttt gaggcattca taattatatg ttcgaagaga gactaaaaga 22441 tggcataaaa gttgctccta cttccggtat ttccatatcg gatagaacaa tagataattc 22501 ataaacaaga caaggggcaa tgtagctgtc tacaaactgc atgaatattt acccaatctt 22561 cccggaagaa acactcttgc atccgactat ttcgcatttg atgtttcaac agcccttggt 22621 gtgccttcag ttcatcactc aagagaggtt tttcatgaat accatgacca aagatttgta 22681 tttgaaaaca aaaagcgtta ttgggaggga attgcaaaat tttcggacta tttcaatttg 22741 tacatgtcca tctttaacga caatttggat atgaaatacg gaaataccag aaataaagtt 22801 atttccaatg acattacttt tgacattgca aataaaataa aaaacttaaa aaatgaatca 22861 agggtggttc gtgagaacag aattaaagat attgcaaatc acatactttt accctttgac 22921 gaaaaatata atgccattgg aaaatttata ttgcaaacag cacaaaatat tgtcgatgaa 22981 gccaaccgcg aatatcttct tcatgctgag ttgattgata aatggcctca aatagtaatt 23041 aaagccaaaa atattaatct tatggatatc atttagcttt ctaatgcgac ttgacaagct 23101 cttttataat gagaactatt cctgttaaaa aagccgccaa aaaagctatt aaaacaaagg 23161 cataaagaaa tgtattcacc ggcagcatcc ggatctcctc cttctttccc gtattcaccc 23221 tgccacaatt agacaacgta cattaaaaat catgtttttt acatgcaaaa gttttttgct 23281 ttatatttaa ttatttattt taatatatta cataaaaata ttcaatatta ttccatttct 23341 taaattaaac aaaaggtaat gcgaagtttt atatacttcg gcattacctt ttatctgcac 23401 caaacccatt tattccacgt tgtttatttt gtcaaccagt tcctccagca tttcttcgct 23461 taaccttccc tgagagtaac cgacaagtga gcgcaaaggc atattcttta tattggccgc 23521 catcatgtca tgagcattgt ccatatcaat ctgcagtgca tcggttatct cttttagtac 23581 aggccctaaa acggccgcag ccgaagaatc ggacattaca tcttcaaccg ctgaattcac 23641 tgtgaatctt tttcttatct tcaccgttga atttactctc actgattctt ttaaaactat 23701 gtccctggag gaccttccta ttaatatcag aaactctccg ctttcaacat gccagtcctt 23761 aatctgagta ttgtaatatg caaaagccct tttgtccaaa gtaaatgtaa ccgtcttttc 23821 ttctcccgga ttaaggaaga ccttttcaaa tcctttaagc tctttctcag gtcttctgac 23881 gctgcttttc acatctttta catacagctg cacaatttct tttcctgcca tttttccaac 23941 atttttgact ttaacgctga catttatgat gctattgtcc gaaacatctt ttttatcgac 24001 tgatatatca ctgtattcaa atttggtata gctaagtccg tgaccaaagg ggaacaatgg 24061 ctcaattccc tttgtatcat aatatctgta tccgacaaac aacccttctt tatattccac 24121 tcggtcatcc tctccgggaa aattcaaata ggacggatta tggcttaatt tcaccgggaa 24181 ggtctccgca agttttcccg acggattgac ttcaccgaat agcacatccg ccagcgcgcc 24241 tcccagcgcc tggcctccaa gataagcttc aagcacggat tttaccttgt caatccacgg 24301 catttcaacc ggtgagccgt taagcaatac cacaacaata ttactctgga cttcggccac 24361 cgcttctatc agcctgtttt gattttccgg aatactcatg tgagttctgt caaatccttc 24421 agattcatat tcatccggaa gccctgcaaa tactaccgca acatccgagc ttgatgccgc 24481 ctttttagct tcgtttatca attcctcatc aataccgtca ttttcaagcc tgtatccttc 24541 cgaatataca aggtttactt tgtcgcctcc ggcctttttt atctcttcat aaatatcatc 24601 aagtcttgtc ggggtaatat gagaactgcc cgaaccctgg tatcttggtt ttttcacaaa 24661 agctcctatc aaagctatgg ttccgctctt ttttaaagga agcacatcgt cctcgttttt 24721 aagaagaacc atcgattcgg ccgcagcctg ccttgccagt ctgtgatgag catctttgtc 24781 atactgcgcg ttttcttttt tgttttccag tgccataaaa attactttca aaattctttc 24841 cacagctctg tttaaaatat tttcagacag ctttccgctt tttacggctt caactatctt 24901 tttatccgta ataccatgac tggtgggcat ttccaggtca agacctgcat ccaggccgct 24961 gaccctgtca tttaccgcac cccagtcgga taccacaaag ccgtcatgca tccattcatt 25021 ctttaaaact tccgtcaaaa gatatctgtt ctccgaacaa tattcaccgt tgagcttgtt 25081 atatgcacac ataaccaccc aaggccgtgc tttttttaca gcattctcaa agcttgcaaa 25141 atatatttcc ctcaacgttc tttcatccac aatggtatca acggtcattc tccggtgttc 25201 ctggttgttt gcggcaaaat gtttaagaca tgcacccact ccctgacttt gaactccttt 25261 tatatggctt gccgccagct ctgacgaaag ataagggtct tcggaaaaat attcaaaatt 25321 tcttccacac aaaggtgaac gctttatatt tgcacctggt ccaagcagta ttgagacatt 25381 ttccgcctga cattcttctc ctagtgctgc acctactctc tcaaccagtt ctctgtccca 25441 ggaacatgcc aaacctgctg cagacggaaa acaggttgct ggaacgctgt tgttgatgtc 25501 cgcaatctct gcatcttccc tctgctttct cagtccatga ggtccgtcag tcatcattat 25561 tgaaggaatg cccagtctct caacaggctt ggtatgccaa aaatccagtc ccgagcacaa 25621 ccctgctttt tcttccaaag tcatctgctt tattattttc ttgatatcta ccgccatttc 25681 tatcctcctc atgctttgcg tttatatgtg catatatatg ttaaatcgtc ttttggcaac 25741 ccatcagttt atatcaacct tcatcgtgac attcaccgtc atgtcgtcaa aatgtttgtc 25801 cacgctcttt gaatgaatgt ttcctgctcc gtcaacgtaa ttaaaattgt atcttagtct 25861 ggaatctgcc ccgtcaaata ctattgtgcc cggtttgagg aattttactt ttattttgaa 25921 gctttcaact acaaaactgt aacccgtgcc tgtaaacgta aacggaatgt tgtttatctc 25981 accggtaagc tttatcctgt taactccgcc catcggcaca ctttccgtgc ttatccactc 26041 aggagcctca accagcagca ctccctgcgg aagaatctct tcgtacaaaa ccttgtcaag 26101 cacaacatca taatatatct tcaaagtcat attgtttaaa atatccagaa gttccaggaa 26161 attatttgcc ttgtaatagt gtctgtctgt tccttctaac ggttttgctc cgctttctgc 26221 tgcaatttct tccagtacgt cgccaatatc ctcttctgaa aagtctataa acacaagatt 26281 gatacccttt gaagtaatga ttcttcccat atcctttgca taatccagtg aattgtatga 26341 ctcattgtca gcctttataa aatcagcacg tccgttgtct gtcttcggtt cattcttttt 26401 attgtccact gccgtccacc ggttcggtac agagcctgta ataacgacta tatattttga 26461 aatctgacct tttggaggag gaccattaag aatatgatag gctcttctca ttccgtcacc 26521 catgttgctc aggcctgatg ttccgggctt aattttgtca atagtctcct tcaaagcagc 26581 tcctttatca ggcaaagaca aatcatactt tttaaaatca ttatcattgg cagaatcgga 26641 atactgaata acggccattt tggtcttaga acccgcaaac ttgtctacaa agttctttgc 26701 agcatctttt accaatttta aataagtgga tttgtcaata tacttttcct caacagtatc 26761 aaattgccct tcagtatgat ttaccacaag gccgccggca aaaaaatcaa gttcgttcgc 26821 tgcaatagaa ccgttaattg tatttttgtc acctgagaag aaaatttttc ctgaattagg 26881 gtttgcagga tttccaggtg cataagctat tccgtttata gtagagttac tggtctgaaa 26941 ctctatattt ccccctatgg agtaaacata caacttgtca ttaggtccgt tgggatacaa 27001 gttttgtccc tgtataatta tatttccgtc agcaacaata aatccctcac cgacgttatt 27061 ggtatttgtc agtgatataa gaacattgcc cataaaatac attgaagaat ttataacaag 27121 tgtacctgct ccaaatattt caaaccgtcc ggcaattaag ttataaaata taaagatatc 27181 ttcttgaccc ggcattggct gggggaacca actcaaaaaa taatcctcag gtctgaaaac 27241 catggaattg cgcatcgcat catcaataag tttagaatgg aaattgggca tttctattgg 27301 aatcgtaatg tttttatatt catttatatt tacgttttta cttgtaatgt ggaagctggc 27361 agctgagcaa gtttgagaaa tacttatact atccgctgta gaagtaaata catcatttgc 27421 atgcacactt ccgttaatgg aagcatcttt tccctgtaca gttaaattat gatttgaata 27481 tattccaaag tccagcggtg ataaaatatc ttccacataa gaatttaaca cacctgagtt 27541 atccaataca agcacaattt ctttttctgt gtccatcctg ccttccaaag caatttctcc 27601 gctttgggat aatgttatgt caacttcttc tccaagctcc gcctcatata cggaacttct 27661 cgaagcggtg ataccggctc cctgagggtc ctccgacggc acgggcgata cggaaggcga 27721 agctattttt tcaatatgta cattgtcaag aacaatgtca tgggctttat ccgtctctgt 27781 tccgattttc cccatttcaa acacaatcgc cacatttgta cctgttgtgc tgttaaatgt 27841 gaattcacag gtataagtct tcatctttgg ctcaacttcc actatcttgc cgaaatactc 27901 aatcatactg cttgtggcat tctgcaatga cacccttata tttctcggaa ccgttgactt 27961 tgcatcaaaa gtaagcctgt aggtttttaa attttcaagt acaattccgt catgcttcaa 28021 ttgaattgcc cagtgattcg agcctgcatt cgtaatagaa gttttggaca ttttatttcc 28081 ggaaggctcg gaatggatca aatttgtggc attcgcaccg gataagctgt cgcagtaaaa 28141 actccaaaat accgatccgc tctcaaaatc tccgttggga actgcttttc catcccaatt 28201 tacaggagtc tcaaaacctg aaggtgttgg cgtggcctgg taagtcggaa cagacgaagg 28261 tgttgcaacc ggcgtcggac tgatttgcgg agtcggagtt gacaaagaag gggtgggact 28321 atacattacc ggttccgttc cactgaacaa aacgccgttc aaatacccag taaccttgtt 28381 ccatgccgca aaatcgttat tagactgaca gaaagaataa tcattggttt gtgtaaaact 28441 ctgtttgtat tcggattgat aggctctggc tctcattaac acggatgtat tgggttcaag 28501 acttcccgcc tgagcgttaa atccaaattc aatatatttg tttgctccgg atgaatttat 28561 atcttttata gtataagtaa catcgttgtt aattcctctg ccgttattgt tggcataatc 28621 gataaaaaca gtaattggag acactccgtc atcagtaaaa tagtatctta atttaatgtc 28681 cgaaagtgaa atttgagaag aaccattgtt ggtaattcta aaattcatag aaatggaaga 28741 aacagaagca ccaaaatctc cattatagaa ttccaaactt atgtttgcag aatttgcata 28801 gacattcaaa ccaaaagaag ctaaagatat gatttgtatt aatatacaca ctgcaataag 28861 caatgcactt tgcttatatg ataatctccg tagcatattg catccatccc cctttatttt 28921 tgcgttgata agtacgaagc aattttatgt cgattgtgta atgtcgactg gttgattgca 28981 ctaatgccaa actatgacaa attataaagg atgcattata aattatactg tgaaatttta 29041 atcggtttat tggaatctcc aagtgtcttt acaagaatag tcttaggatt aaaagaagca 29101 ttcaggtaaa tattaacctc aaacaaattc attccaccgt ctttacctgt tatttccgct 29161 ataccgctca catattttct tgagctgtca tacaactcta tcataagcat cttgttttcc 29221 aaattcactt ttccatatac ttttaatatt tttccgtccg cttcactttc ccatccgtcc 29281 acagtaaact ccaaatctct gaagtaggat ttctccccta aatcccgtac ttggttaaca 29341 taagaaatat aaaccgttct tctggcaccg tcccaggaaa catctgctcc cgcattctca 29401 cttacaaatc gtaacggaac aaaagttctt cctcccacga tctcagcctc agcatcaaga 29461 tttactttgt atccgttgac ataagcaaag gctttcccta tttcaatata aatctcggtg 29521 gtatcattgg ttgccagaat ggtacggttt actccgttcc agcttatatc cacaccaaga 29581 gcttcgaaaa tcgctctgaa aggcaccatc gttcttccgt tttttatgta cggagccaca 29641 tcaaacttaa tttcaacccc atttagaaaa acctttattt catccgccga agcataactg 29701 ttttgtacgg caaatgagaa gcttcccgta aagctaaata taatcaaaat gcaaaatacc 29761 acaagatatg aaaaaaacac tcttattttt ttcataatca ccctcctcca cattgagatt 29821 ttgagaacaa cacatacaca ggatttagga ctctttcgga tttaagaatc tgtcccacac 29881 tttcctgaat ctgtctaatt aactattggt ctaatcaact attgattgaa cgaaagaaaa 29941 aatcagaaat gaaataaatt tatgcaggcc tcgatgaaag ttctatctaa taaactatta 30001 taaagttaca ttttccctta tattaattat ataacgaatt tggtgtttaa gtcaacttta 30061 tgcaagtctt tgtaattata ttgacatatt ttgattgagc aaaattttag taataacagt 30121 ataataatgg tattgttatg taaacctaaa taaagatttg taaaaaaaat aatttatttt 30181 aaaaggattt aattatcctc attattttga tttcattgta agtcttccaa actcaattgt 30241 atacataaaa aaagcaaaca atgtggaacc aactgcgatt ataacggcaa tattaactat 30301 tatatccgag taaggatttg caaacagccc cgatcttaca agtatagtta atactattgc 30361 caggaaaaaa acaactgtgg caaacttacc ataccagtca gcctgtacaa caaaatttac 30421 cttcttgtat attaaaatac tgccgataat cataaacgac tcttttgcaa caacaattat 30481 caaaaccggc aacggtataa tatcctgtat ggtaagaata gtcaatgctg tcaactgcat 30541 caatttgtcc gccaatggat cggcaagctt tccaaaggac gtcaccatat tgaattttct 30601 cgcaattatt ccatccaata catcagtaac tcccgccaaa agaaacaaaa tcacggcaac 30661 ggtatatcgt tcattataga ggtagtatcc aaaaaacggt ataaaaacaa atcttatggc 30721 agtcaatata tttggaatat tcacctattc accaccttaa aaaaattata acaatttata 30781 aaacagcctt atttaacaat tcaaaaatat ccggtgcatg ttttttaata tttacaggct 30841 taagattttt gtttgtccat gcatgcaccg tctcccccgt tgttatcagc gaattgtcac 30901 aacatttaaa aacctcgtag taaaacgtta ccctcgtata agacatttgc ctgatacaag 30961 tttttacaat gagcctgtcc tcatatcttg ccgcgccttt gtatctgcat gtaagttcaa 31021 tcaggggaag cataaaacct ctttcttcaa tttttgaata ggacattccc aaatttttta 31081 taaaatccgt ccttgccgcc tcaaaccaga taggatagtt cgaatgatga actattccca 31141 tccggtctgt ttcagcatat cttacaataa tctccgtctc cgatatgaac aatgcttatt 31201 caccttacca taatatacag ctctttatta ttataaaaat attataaata aaaattataa 31261 aaaataattg cgtaacaact aaagcaaatc aaattgcatt ctgacgctta ttattataat 31321 gctaatattt tgctaagctg aatcaaatct tccgaaatgg tctttttaac ctgcaaagct 31381 tcttccaaat ccatatcacc tatctggttg tccttaaaga caattactct gttacgcttg 31441 ttttccatca aaacttcaac agccttcgct cccatctgac ttgccattac tctgtcgtat 31501 acagtgggac tgcctcccct ttgtatatga cccagtatgg tggctctggc ttcaataccc 31561 gtcttttccg taatctcttt cgcgatctcg atggctttgc cttctccccc ttcggcaact 31621 ataacaaggt agtgcttttt gcctctgttc cttccctcaa ttatgggctt tatgacatcg 31681 gtatccatat caaaaggttt ctcaggcaga acgacagcct cagcacctcc ggaaatactt 31741 acattcacag caatatatcc ggcatgtctt cccataactt ccagcacact gcatctttca 31801 tgggaatatg cagtatcgcg tatcttgtct atcgcatcct ggacagtgtt catggcggta 31861 tcaaaaccta tggtataatc ggtgcaacca atgtcattat caatcgtccc gggtattcct 31921 atgacattaa gtccaagttt gctgatgtct cttgctcctc tgtaagaacc gtcaccgcct 31981 attaccacaa gagcgtcaat accaaatact tttgccatgg acatggcttt tttaagtcct 32041 tcctcggtct taaactgggg tgatctggct gtctggagaa tggtacctcc cctgtgaatt 32101 atatctccca ctgatcttgc cgtcagttct tcaatatctc cgtttataag accgttaaaa 32161 ccctttctta ttcccaaaac cttaaagcca taatacagtc ctgttctcac aaccgacctt 32221 atggccgcat tcattccggg agcgtctcca ccgcttgtca aaactccaat cgttcttaca 32281 ctgctcatct acgacaaccc tccttaatag tattaaaccc gtgttttaag aggctaaaca 32341 cgggataata aaaaaaacta tattaacttt aactcaatat cccttttcaa ttattacact 32401 atgggcctct tccacttcgg cttcagggac taaaacttcg taatagttgt cattattgtc 32461 gtgatttttg ctgataggtc ttaatttaac caaaatccct tcgctcgtca acaattcctg 32521 catcgtagtg gcgatctctt tgctttgagc catatacacc actgtccaca tataaacacg 32581 ccccttttta cgttattcac cggaataaac ttctccatgc ctgctcagta tcctggcttt 32641 tcctctgatt tttatcgcag aagtattatc ggtaaactgg gcaataagaa cttcaccctt 32701 atccagtttc tcggtatggt ggaacttcgt atctttacct ctggtaaggc caataatatt 32761 cacaccattt tcttcagcct taatcacaat ataatcctca tatattcttt ccatattcga 32821 atccaaagag aaccacctcg acataactat atattaattt gcaccaaaaa tcaatatgaa 32881 ttttaggcaa aggttacgag actttgacat tttcctcccc tataagtaac ttcaattcat 32941 taatcacggt gtcattaagg cttacccagc aatccctttc caacaccttg atcttttttt 33001 ggctttcatt gtaaaggcat acaggagtgt tcccaccaaa aaacttcagc atgcaaatta 33061 ttgattccat cagctcgttg tcaatgttat cgtccactct caaataaagc tttaccactt 33121 ttcttttcag cggatttgcg ccgtcttctt ttcttaacgg ccttacttcc tcgcatatta 33181 tttttggctg ttcctcttct tttatactta tacttccttt tatcagaaca atgttttcca 33241 cctccagaag gttcgaaaac ctctccaaaa cagcaggaaa aactattatc tccattgtgc 33301 catacaaatc ttccaatgtc acaaaagcca tcaaattgtt attcttcgtg gtttttgtct 33361 tccttgaagt aattattccc ccaaccgtca cagtcatacc gtcttttaaa cctttgtttc 33421 cttcaacagt tattacctca ccgttttcat ccgcatccga caccatatcc ttgctgtaca 33481 atgtaaccac ttcactgaat tccttttcaa attcactcaa aggatgtccc gatatataaa 33541 ggcccagcat ttccttttcc attgacagaa gtatcttctg cgaatattcg ggaatatcgg 33601 gataaatatc ttcatcttcc ggatatagct gatgcttctc atcctttttg ccatcctcgg 33661 tgttaagtgc catgtcaaat atggaaagct ggccttccat gctctttttc ctctggctgg 33721 atattccttc catcattttc tcataagcat tcataagcct tgaacggtat actcccattg 33781 aatcaaaagc tccgctcttt atgaggcttt caatgcatct tttgtttaca tcctttccgt 33841 caactctctc caaaaagttc ctgaaacttt tatagtttcc gtttatattc ctttcatcaa 33901 taattgacct gactgcattc tcaccgacat ttttaaccgc tgcaagccca aatcttatct 33961 ttccgttcac aacggtaaat ctgacatcgc tttcatttat atccggagga agtacttcaa 34021 tacccagctt gcggcactca tgcacatact gggatatttt atcgctgctt cccataaaac 34081 tgtttaaaag cgctgcaata aattccacag gataataaca tttgagccat gcagtttgat 34141 acgctataac cgcataagca gctgcatggg atttgttaaa cgcatagctt gcaaagtcca 34201 tcatctcatc aaatattttg tttgctgtct cttcatccac accgtttctg acagctccct 34261 ttactataat atttccatta tcgtcatcta ttccataaat aaaatttttt ctctcctgtt 34321 ccattatact gacctttttc ttggccattg cacgccttac aagatcggac cttcccattg 34381 agtaaccggc aaggtcgcgg actatctgca ttacctgctc ctgataaacc atgcatccat 34441 aagttacatt cagtatgttt tccagcaaag gatggtcata ctttacaagc tccggattgt 34501 ttttgtttct aagatatctt ggaatctgat ccataggacc cggccgatac agggatatgc 34561 cggctattat atcttccaga gacgccggct gaagctcctt catgaactgg gtcatacccg 34621 cactttccaa ttggaacact cccgccgtcc gtccctctcc tatgagtttg aacacatttg 34681 ggtcatccat ttgaagctcg tcaattttta catctatatt gtgattcttc tttataagag 34741 ccaccgcatc ccttattacc gtaagagtcc taagtcccag aaagtccatc ttgagaagtc 34801 ccagttcctc caaaattccc atgggaaatt gagtcgtgat actgtcctca ctcctttgaa 34861 ggggaacata ttccgtcaga ggttcccggg aaataaccac tcccgcggca tgggtggaag 34921 catgtctcgg catgccttca agaagctttg cggtatcaat cagctccttt accctttcat 34981 catcattata cctctggcga agctcgggat ttagctccat ggccttttct atactcatgc 35041 caatctgaaa aggtatcatt ttggcaatgg catcaacctc tccataggat atgtcaaggg 35101 ctcttcccac atcccgtata accgctcttg cagccatggt tccaaaagta attatctgtg 35161 caaccctgtc ctttccatac ttttcgacaa cataatctat aacttcctgc cttctttcga 35221 agcaaaagtc tatgtcgata tccggcatgc ttattctctc cggatttaaa aatctctcaa 35281 acagaagatt gtactttaac ggatcaatat ttgtaattcc aaggcagtag gccacaaaac 35341 ttccggccgc ggaacccctt ccgggtccca ccattatccc tttttccttt gcatatctga 35401 taaaatcgct cacaatgagg aaataatcca cataacccat ctgctttatt accgaaagct 35461 catattcaag cctgtttatt ttctcctcat cccggttgtc ttttccgtaa attctttcaa 35521 atccctcata gcacagggcc cttagatatt cgaaagggtc ttttccgtcc ggcacgtcaa 35581 atttgggcag gtgcagcttg ttaaactcaa gctcgacatt gcacatgtcc gcaatcctta 35641 cggtatttga aattgcttcg ggaatgtttc tgaaaagact gatcatttct tcaggggact 35701 ttatataaaa atcatccgaa gaaaacctca ttctgtcttc gtcattgata ctctttcccg 35761 tttgtatgca aagaaggatt tcatgggcac gggcatcctc tcttctaaga taatgggcgt 35821 cattggtggc aacaaggggt attcccgttt ccctgctaag ctttataagc tgctggttga 35881 ctatgttctg ctcttcgata ccgttcatct gaagctcaag ataaaaatta tcctgtccga 35941 aaatgctgtt gagcttaagt gccagctcct ttgccttttc ataattgttg tttaaaatcg 36001 ctttgggtat gtctccggaa aggcaggcac tcatagcaat caagccttca ctgtattttt 36061 cgagaacttc catgtcaacc ctgggtttat agtaaaatcc ttcggtaaaa cctatggata 36121 caattttcat cagatttttg tatcccgtat tattttttgc caaaagcacc atatgaccgg 36181 gatccgaatc ccagcctccc tgtttgtcaa accttgaccc tttggcagta tatatttcac 36241 acccaagtat gggttttatt ccattattga cggcttcctt gtaaaaatca acaactccgt 36301 acattacacc atggtcggtt attgctatac tgtccattcc cagctctttt gtacgcctta 36361 tgaggtcctt tattctgttt gccccgtcca aaagactgta ttcagtatgg acatgaaggt 36421 gtacaaattt ctgcaacatt atcacccttc gtattatcat ccatcggcat atttttcggt 36481 atattataaa aaatattttc atgaatattc atgaaaactt acggcattca aatcatgtaa 36541 acttcacaac aaatatcacg tttttttatt ttcaattata acgaatattt ttggctgtta 36601 tatttaatta taacacacta taaaacacgg taaacaaatt actttttaaa atgataaatt 36661 attaaaaatc tcaaaacaaa taatgtgcat gcagcacctt taacaacgga aggtgacgca 36721 tgcacatatt tttcatgcca aaatatacaa tatattttac aatcagtctt taagaagcgg 36781 ttctataact gacagtacat tatcctgcaa atgtttcaat ttctcttttg cagcatccat 36841 actcttttct gtaacaccat aataaatctt tattttcggc tctgtgccgg aaggtcttat 36901 acagaaccag gctttatcct taagctcata atacaacaca tccgactcaa caagtgtaag 36961 tttctctttc gcacccgttg ccacttcata ccgttcactt gtcaaatagt cccttacggc 37021 aacggcttca tattctccaa attttacaac tctgttttct ctaaggtttt tcatagccga 37081 ctttatcttt tccacgccgt cttttccctt gagagtaaac gaagtaattc cttcaagagt 37141 gtatccatat ttctcaagta actccatcag tccctcgtaa agagtcagac ctcttgattt 37201 gtaataagcc gccatttcgg caataagcat ggatgcaaca acagcgtcct tgtctcttgc 37261 aaaagttcct gcaaggtatc catagctttc ttcaaaacca aaaagatatt ttttgtctcc 37321 aaactcatcc agctgcttaa ttttctcgcc tataaactta aatcccgtca aaacttccac 37381 aagttccaca ttgtaagcat cagtaatagc tctggcaagc tccgttgtaa ctattgtctt 37441 tacgacaaat ccgttttcag gaagctctcc tctttgcttc ttttgagaca gtatgtactc 37501 aagcagcaaa caacccgtct gattacccgt aagaggcaca tactcgcctt ctttgtttct 37561 tacgacaata cccactctgt cacagtcagg gtcggtacct atgataaggt caacattttc 37621 tttttttgcc agctcaatgg caagctcaaa cgcttccctt tcctccggat tgggtgattt 37681 taccgtggaa aattcgctgt ccggaagctc ctgttctttg accacaagta catttttaaa 37741 tccaatttcg tcaagtattc ttcttacagg tttgtttcct gtgccatgca acggcgtgta 37801 cactattttg aaagttttgc ctatttctgc agccagttca gggtttacag aaagagtttt 37861 taatttcgat atatactcat cgtcaatttc cttgcctata atcctgagca aacccttctc 37921 tatcgcttcg tccttttcca taaccttaac ctgagttata tcctcaattt tatttatata 37981 ggatataact ttgtttgatg cctctacagg aagttgtccc ccgtcttctc cataaacttt 38041 gtatccatta tactccttgg gattatggct cgccgtaata accacaccgg cagctgcatt 38101 taaatgcctt acggtaaaag aaagttccgg tgttggtctc aattcatcaa aaagaaacgc 38161 ttttatgccg tttcccgcaa aaaccttggc agcttccaaa gcaaattccg gggatttgta 38221 acgggaatca taagcaattg ctattcccct gtcttgcaat ccaagactct ttatataatc 38281 cgcaagtccc tgggaagctt ttctgacggt gtaaatattg attctgttgg tcccggcacc 38341 gataattccc ctaagtccgc cggtaccaaa ttccaaatcc ttgtaaaacc tctcttctat 38401 ttccttcgga ttgtctttaa tactcaaaag ttctttcttt gtttccgcat caaaataatc 38461 attctccacc caaaatttat aaagcgcgct acttcgcata tatttctctc cctctataaa 38521 aaattaattc attgatttcg cataaatgct ttttctcctt ccctagtata ccacatttta 38581 tccatattac aatataaata ttacgtttat attttaaata tgttaatggt ctgttcaagt 38641 tttacagaca attcactcaa attttcggag agggagagaa gatgttttat caaatccacc 38701 tgttcatcca ttgcggcaga aatattctgt atatccctga tattgttttt cgtactttca 38761 ttcagtcttt ccattgactt gataatattg cagcgggctt cttctatatg ctgcacataa 38821 tccgtaatac ttgtgatcgc actaaatacg ttatccataa atcctacaat attgtcgaac 38881 ttgtttattg tttcaacaac ggcaaggtca tgcccgctta ttacctcgcc ggaagacttg 38941 acagcctcat tggttttttc aatggtcttg cctatatttt taagtttgga ttcaatataa 39001 tttgcagaca ctttcgactg gtcggcaagt ttcttgattt ccgacgcaac tatactaaag 39061 ctttttcccg cttctcccgc tcttgcagcc tcaatggttg cattaagcgc caaaagattg 39121 gtctggctgg aaatgccttt gatggtggaa gttatttttg aaatttccgc agactctctt 39181 ttgagacttc caattagttc tgagaattct tctatggtct tttttacctc atcggcattg 39241 tttttcagca tattgacagt ttcttttcca gcttcgctca actttttggc tccggtaacc 39301 atattgctga catttttgaa atcatcgata atcacttgaa tttgctccga caattcattt 39361 actacattat cattgttcat tatttcctgg gtctgggaat taatctcatt tttcatttca 39421 tccaacatag ctgaaaattc ctggatcgat gcatagctct cctgacaggt cgcagatacc 39481 gtttgcgatg attcaacggc tatattggaa gcatttttta tgcttcctat gagctttttc 39541 aagttttcca ccatatccac gaaatttatt cccaattttc ctatctcatc ttttctggtg 39601 gtatcacatt ctacttcaag atctccctct tttattttat tcattaattt taccagtttc 39661 ccgatacctg aagaaatatc gccggtaatc agcactgaaa gcattattcc tattataatg 39721 catacaacgc ctataagtac tataaacccg gctaccgaat ttacatcccg ggttatgttt 39781 tccaaaggcg ttatagatat caaagtccac tccaaagggg tgcctttaat ttctcttata 39841 gtgtaaaaag taaccatcat ttttttgccg tttataataa catcatcttc aattataccc 39901 ccaaaagcgg tggcctgtct gtttttcgtt tgaatctcat ctatactttt ccttaccttt 39961 tcaagaatac gaagatttat atagttgtcc ctttccctca agtctttgag cgttttttca 40021 tcaagttcca ctcctgtatc agctttatac aacaactctt ttacttccga atcttttaga 40081 tccaataatt ccgttttctt cagcaattcc gctttggtct gtcccttgct gtttacataa 40141 cacagatcct caatcaaaag cccgttgtct cttttatcct ggggattgaa tatcatattg 40201 tctttgcttc ccactataaa aaagaatccg ttatgaggaa tatgtatgtc ttcgagcata 40261 cgagtcaggt aatcctccct gaggtttact tgaagaacac cgacactttt caggcttgtt 40321 gatttgtaaa ccgctttcat aagggcaatc gtagtgttgc cgccctttct tctcaggtag 40381 aataaatcgg ctatatgtgt atcaatccac aacgattttg cgccgctttc cacaaattcg 40441 cgggcagcca cggtatcata gtaatctttt ttcacgtctt caaatgttcc ttctcctcca 40501 agaattacat aaccattgtt ggaagccaaa gtgagatttg aaattgtgtc aactctgtaa 40561 ctttggtaag cattcaaata gggctttata atcccggccc atcgcgcacg catgtactca 40621 ctttccgcac gattgatttc atccaaagcc ggtgcaattg taatatccct ggtgatagtc 40681 attgccaaat tgtcaacttc ctcaagaaca atttttattt tgttccccgt ttgctccata 40741 agtcccaaag tactttcttt tgcctgttgt atcatggtat ttgacagagt aagaagagaa 40801 tatcccaaaa ccactgacag aagaagaatt gttataacaa aggaaagatt tatttttatt 40861 cctattttta ttttatttac tctggacagc cggattattt tttcaaaccg gtttttatca 40921 taaactttat aggtatcgtt tctttccttt ttctttgtat cattctgcaa agttttcatt 40981 gattttcttt ttaatttgga tttggttaat tctctgactt tagaagttgc cctggcaatt 41041 acaactttta ttccgttaac aggaccaaaa ctcatagttt cccacctctg tgcgtttttt 41101 tggacgcgct cacacaaaaa tttcaaaagt ccattgggag ctatgtagga attgcgttat 41161 aactgcagca attttacgac aaatacaaca agtatataag gtaaacagtg aatatacata 41221 catatttcag tattgatatg cagagtaatt tataaattac atatgactta tattatgatt 41281 tatcgtttca aacttttatc aactttatag aaaatttcat tttaaaagat tcaaaaacaa 41341 acactatata tccttttatg taaaatcagg caacaagtac cagctctgac ttaagcaaat 41401 ttacaacttt gaacaaagtt tgaggcagga atttgaagat tatttcgtga tattgtgctt 41461 ataggcatag attgcggcct gtgtcctgtc tgacacatta agctttttga aaatgtttga 41521 aacatgattt ttgactgtct tttcactaat aaagaggcgt tttgctatct ccttgttgat 41581 aaggccctga gctataagct ccaaaacttc aagttccctt ggcgtcaaat cattttccgt 41641 ttttttggcc ttctcattta ccgttactct gttaaactcc ctgacaagct ctttggtcat 41701 attggattga atataagact cgcctctgtt tacgcttcgt attgcctcaa ccaataccgt 41761 ggaatcggca tctttcaaca catatccttc cgcgcccatc tgcaaagttt taaacagata 41821 ctctttatct tcatggatgg taagcacaat tattttgact gcaagattct cagcctttat 41881 tttttctatt gcctgcaaac cgttcattcc aggcatgtta atatccataa gaactacgtc 41941 cggctgacat tcctttgcca attttacagc ctcttcgccg tttgacgcct gcgctaccac 42001 agcgatgtcc ttttcaagct ccaatatttg cttgagacct tctctgacca tggcatggtc 42061 atctgcaatt acaacccgta tcttatccat ttgagacccc ctcttccggt aataaaggta 42121 cagttatatt aagtctggtt cctttgccaa cggcagaatc aatctcaaat ttgccgtcca 42181 aaagctcaac cctttctctc atgcttataa gaccgaagcc tttgtttata tcctcttcgt 42241 ttgattttaa agaatcaaag tcaaaaccta ctccattgtc tgctatatag agctttaatt 42301 ctttttccaa aaattcgaga tttatagtta ctttatcggc acgggcatgc tttttaatat 42361 tattgactgc ttcctggaca agtcggaaaa cggtcaaaga aaccacaggt ttcaattgct 42421 cacatgtacc tcttgtctta aacgttattt ttattccgga ttcttcccga caagtctcta 42481 tatacctttg aagggttggt atcaaaccca agtcgtccaa tgacattggt cttaagtcat 42541 atattatttt ccttacatcc cgaagagtgt ctctgacaac ggattttaaa gttctaagct 42601 catcttttgc cttttccggg tcagagtcaa ccaatctttc gcatatttcc gcctttaaaa 42661 caatattgga catcgattgg gcaggaccgt cgtgaatttc ccttgcaacc ctctgtcgct 42721 cctcttcctg ggcttttatt atccgaatcc ccaaaagccg cctttgtttc atatcttcaa 42781 tctgcaaact gacattctca agatctccgg taagatagct taaggaaatt ccaatctggg 42841 agataaggtt gtccgccttt tcaacggttt tataagcctc tttaagcctt atttccaatt 42901 catttcttct tttgatatag tattgctcac gctcccgttt tatggcaagc tcaaccctga 42961 tattgtctgc attttcataa gcttccctta attcctcttc agaatattta tcgtaatttc 43021 tgctcacatg cattagccgt ttcttgcttt cataaagtgc aacctcaagg gtttccacac 43081 ttttgataat ttcggatgtc ctgcgcttta actcctccag ttctttttca agccttacgc 43141 attcatttct cgcgttttcg gctatgtcaa acaattcggc tttactgtta tttatggctt 43201 caattgtttt cttaattatt ttatccaaat tagctgtgtc tactttttta taaccggcca 43261 ctttgatacc tcaccatttt tccaattgat atttatttta cacaacacca tgaaatccat 43321 tgatatttga cgccgcttag caattaaaaa attcctcact agttatatcg tcttatgcct 43381 gtccattgtt aaatccgatt ttttaaatgc atattattcc cctatttgtc ttttgtaaaa 43441 tgtgttataa tgttttaaaa aaaaaagaag aaaggacaag caaaagatga agtcaaaggt 43501 agcaattgtc agaaccaaac cgtccacggt acttgaagat tatcatagac tgatgaatct 43561 tgccgaatat caaaactata tttccaaaga cgttgacact gcacttaaaa taaatataag 43621 ctggcatttt ttctacccgg gaagttcaac aacgccctgg cagctggaag gtgttatccg 43681 ggctttaaaa cgtgacggat ataatcctga gcttattcac ggctgccaca acagaacggt 43741 ggtaattgac gctcacctgg gagagcggga aaacaaacag attaatgtta taaaagccca 43801 caatcttcga aacattcatc tctacgaagg cgaggaatgg attgacataa gggaggcagt 43861 gggagatctt acaaaaaaat ttttgtgtct gaacgaagtt tatccgaaag gattttccat 43921 acccaaaagg tttattggtg aaaacattat acatcttccc actgtgaaaa cccacgtatt 43981 taccaccact accggagcaa tgaaaaacgc tttcggcgga cttttaaatg aaaaaaggca 44041 ttggactcac ccggtgattc atgaaacttt ggtggatctg cttatgatac aaaaaaagat 44101 ccacaaaggg atttttgcag ttatggacgg aacttttgca ggagacggac cgggtccccg 44161 ctgtatggtt ccccatgtaa aaaacgtgct tttggcttcg gcggatcagg tagctatcga 44221 tgccgtggcg gcaaaactga tgggtttcga cccgctaaag gactgtaaat acatccgttt 44281 agcccatgat gcaggccttg gctgtggcga cgtaagacaa atcgaaattg tcggagatgt 44341 tgacgccttg aatgaaaact ggaattttgt cggcccctat aaaaaaatga cctttgcaag 44401 caaatgccag cacctgattt actggggacc tttgaaaaag ccggtggaat ggacattaaa 44461 aacaatcctg gccccctggt cctacattgc cagtgttgtt tatcatgata tgtactggta 44521 tccgaaaaac tatggcaggg tcgaggaaat tctaaattcg gactggggac ggttgtttgc 44581 aaactgggag cagcttcagc tgcctgcgga tgacctgtcg gttccgggct gggagcacgt 44641 cggagacaaa ccgctaaaac ttgacaaaga aacaagtaaa atgatacgca aagctttcag 44701 agttcttgga accgcaatca gggaagctcc ggagtttagc gcaaagaaat caaaaaaagc 44761 atgcaaataa aaatgtcttg tccaatggaa ctttatttca ttacttacgt caaaaagcca 44821 gtgaggataa atctgacgga ggtggagaaa atgaaaagaa cagcttgcgc agttttatgc 44881 atatttgttt taacattttt attttccggg tgttcaaggg aaaaaaaggt ttttgacgaa 44941 ttaaaacttg acaccgaact tgaaaagaaa aatacagaat tttgctttga catattctca 45001 aagctgaacg aagaggacta taataaaaac atttttattt ctcccttgag tatttcaacc 45061 gtactctcca tgaccgtgca aggtgccgga accacaacaa aagacggtat gctgaaagct 45121 ttgaaatatg acggtatgga tctcgataaa attaacgaat cctacagata tatactcgac 45181 tatttaagca aaactgataa aacaattgaa cttgagatta ataattccat ctggataagg 45241 gaaggaaagc aaatcaaaaa agattttatt gacattaaca aagatgtata caatgcatac 45301 gttaccgagc ttgacttttc aagcccaaat gcagcagaca ggattaacaa atggatttcc 45361 gactcaacga agaaaaaaat cacagacata attgattcac caatacctga aaatactgca 45421 atgtttctta taaacgccat ttacttcaag ggagactggg cggaaaagtt taaaaaacaa 45481 gatacgttca ccgccaagtt ccaatcgggc aacggccaaa caaaagaagt catgatgatg 45541 gaaagaaaag atacaataga atacggagcc aaagaggatt tcaaggttgt aaggcttcct 45601 tacggaaaag gcacaacatc aatgtattgt gttttgcctg ccaaagacgt ttcaataaat 45661 gatttcataa aaacccttga tgtcaataaa tgggaagaga taaaaaacag tatttctaaa 45721 gctgaaaacg taaccttaaa tattccaagg tttaaaatag cttatggaac taaagaatta 45781 agagactgtc ttattgccat gggaatggaa gaagcattca ccgagcgggc tgatttttcc 45841 ggaataagtg agggccttct cttcatagac agtgtaattc ataaagcaat aattgaggtt 45901 aatgaggatg gaagcacggc ggcaggcagt acagtggtca gaatgataga tggtgctgca 45961 ataggagaac cgctttcttt cattgcagac agaccgtttc tgtttttcat aaccgaagat 46021 gttacaggta ctatactatt tatgggcaaa ttgtatgatt gtgaaaaata ttaaatgaaa 46081 ttacacatat attataataa aatcaaaaaa acacatcaat gaaaggggta tatggctttg 46141 catatatccc ttgttttatt ttcaacttca ttttaaaaaa atcaaaattc ccaacccaaa 46201 cttgccatat gtttcgtaca aataaattga acagaaaaaa ataatgctaa atcaaaatta 46261 atttaaaaca ataaaaattt ataagggagt gagcttatgc caaaaaaact gaaaaaaata 46321 attaagttat gcagcatggt attcgttatc ggcatcttaa cattattact gcctgaaaaa 46381 ggggctgccg attatccgat tttctcacag cgttttactg cagacccagc cgcagtcgtg 46441 tacaacggaa gactttatat ttattgttcc catgactcgg atgccacacc cggccagtcc 46501 acttacaaca tcccggatat aacctgtata tccacagatg atttgaaaaa ctggaccgac 46561 catggagaag tgtttaatgc aaaaagagat tccaggtggg cttcggtgtc ctgggcaccg 46621 tcaattgtct atcgcaacaa caagttttat ttgtattacg gtaacggagg aaacggaatc 46681 ggagttgctg taagcgacag tccgacagga cctttcaaag atcctcttcc gggtccgttg 46741 gtaagctgga atacccccgg agtacagcct gcacaaaata tgtggctgtt tgaccccggt 46801 gtttttgttg atgatgacgg acaggcttat atgtactttg gtggaaacgg acaaaacaat 46861 atcagagtta ttaagttggg caatgatatg ataagcacgg taggttcagc tatgacgatg 46921 tctgctccga gatttttcga ggcagcatat atgcataagt ataatggaaa atattatttt 46981 tcctatgcca gcgatttctc tcaaggtgca tctaagattg aatatatgat gagcgacaag 47041 cctaccacag gttttcaata taaaggggta atattgccgc agccacccga caactatagt 47101 aataataacc atcatgctat cgttgagtat aaaggcaatt ggtatgttgt gtatcacaac 47161 aggactgtgg caaaacagcg tggactggac ccggtatatc agagaaatgt ttgtattgat 47221 cagatgtttt ataacgccga cggtaccata aagcaggttg ttccaacggt agatggcttg 47281 aaacagctca aatatgtaga tccttacaca aaaaatttag ctgtaaccat gcataaggaa 47341 tccggtattg agactgaaga atgcagtgaa ggcggacgta atgtggcatt tattgaaaac 47401 ggagattgga ttcaagtcaa aggagttgat ttcggaaatg taggcccaac cagttttgaa 47461 gccagagtcg ccagtgctac aaacggcgga aacattgaaa taagactgga tagtcctaca 47521 ggaactctga ttggcacatg caaagttgaa ggaaccggag actggcagaa atgggtaacc 47581 aaaacctgtt ccgtcagcaa ggtaaccggt gttcacgatt tgttcttcag gtttacgggg 47641 ggaagcggtt atctgtttaa tttcagctgg tggaaattca actcagacgc aaccccaacc 47701 ccaacccctc ccccccaacc ttcaactgta cctgtaactg aaagaagtgc tttttcgaaa 47761 atagaagtgg aagatttcaa tgacattaag tcttccacaa tacaaaaaat cggcactccc 47821 aacggcggaa gcggcatagg atatattgaa aacggagact ggctggcgta taaaaatatt 47881 gacttcggaa acggtgcgac cacctttaag gcattggttg caagtaccct ttctccaaat 47941 attgaacttc gattagacag cccgacggga acacttatag gaacattgaa agtagcagcg 48001 accggcggtt ttaacgcata cgaagaacaa agctgcaaca tcagcaaagt tacaggaaaa 48061 catgacttgt atcttgtatt ttccggtgcc gtaaatattg actggtttac ttttggcggc 48121 agtagtggca taattaaacg aggcgataca aacagcgacg gaaaaatcaa ctcgacagac 48181 gtcacagcac tcaagagaca tttgctcaga gtaacccagc ttacaggcga taatcttgcc 48241 aacgcagatg tcaacgggga cggaaatgtt aactctacag atcttcttct gcttaaacga 48301 tatatattag gggaaataga aaatttcccg atataagtat tcattatttt ggtttttaca 48361 attcaatata ttttttaaac gatgcatttt atactcgggc ataaaaacca tgcccgggta 48421 taaaatcaat tttttattta ttacgttgtt gatgagggaa gagagatatg ctatttgttt 48481 ctgctattat agattatgcc ggtgaaacag caactcacat tgttgaaaaa atcaaaaacg 48541 gggacaagca tttaaaagaa aagttcatta aagattatat cccgtttata ttaaatattg 48601 tttcaagctt ctactcttca aaaacaggag atctaaaaag cagcgatgaa tatagtattg 48661 gcttgatggc ctttaatgag gctatcgaaa aatttgatgt taataaaagc aaaagttttc 48721 tcaaatttgc agaaatggtt ataaaaaagc gaatgataga ctattttaga aaaacatcct 48781 caatcggcag aaaagaaatc cctttttcct attttaacag caataacgaa actgaattta 48841 gaaaaaaaat aaataacctt gacatcgaag aggaatttaa cagttatgaa tttatttgcg 48901 aattaaggga cttttccaaa aaacttgaaa gctttggact tagcataaac aatttgcctg 48961 attacatgcc caaacacaaa gactcaagag aaatgtgcat aaacatagcc aaaaaaatag 49021 ttgaaaacaa gagtattttt gacaaattaa agacaaaaaa gtacatacag atgaaagagc 49081 tttccaaaat aattgatgtt catccaaaga ccgttgaaag aaacagggct tttatcatat 49141 gtttatgtat attatttgat aatgattatg gaaactttaa atcgtattta aataaaatat 49201 tttaataaat agaaatttta tggaccaaaa agtactttca aacacgaaat tattaaatag 49261 agatattcaa tatgtgcaac gggcactttt cggagggtaa aaatgaaaca caaaggcatt 49321 gtattaaagc tgacaaaaag caaagccata ataagtacca atgattttca atgctactat 49381 atcaaaagaa gccctacaat ttatgtagga aaggaagttg aatttacaaa taaagatatt 49441 gtgacaaaga agtctgtttt aataaaaccg gctttaagcg ttgcctgttt tatattgttg 49501 atagcttgtg ttttaagcct ttcaaaaata atcaataata ttagccctaa agtttttgcc 49561 tatatcagcg ttgatataaa tcccagcttt gaaattgaaa tcgatgacat gggaaatgtt 49621 ttgaatttgc ttccgttaaa tgatgatgca aaggttattg ccgataaatt ggaaattgat 49681 aaaatcaacg tttccaatgc cattgatatt ataataaatg aagcaataaa aagcaatgtt 49741 ataaatgaaa atgaaaagga ctttatatta gtttcaagca ccctgaatat taaaaaagag 49801 gagaacagcc aacagtatca gagtgaaaaa gaaaaacttg atattatcat aaattccctg 49861 aaagacagca tagaaaaaag cggaaaagcg gatgtttaca ttgtccaggc tgacgtgaat 49921 gaaagggaag ccgcacgaag taaaggaata tctacaggaa gatacgtttt atataacaag 49981 tataaagatc tggaaaacga tctgtctttg gaagatgcca aagatgctga tgtcaatgtg 50041 ttaataaaaa gtatgttgga tgtggcatca gaagaaagaa atccggaaga atcaccaaaa 50101 atgaccccaa ctccaacacc gacacataca gcaacacata caccgacaga tgcaccaacg 50161 ccgaaaccgg caaatacacc aacatcaaca ccggcagcaa aaccttcacc aaaaacggca 50221 tcgaactcag cctcgacatc aacacctgcc ccgaaaccta catcaacacc gacaccaaca 50281 ttgatgccaa cacctactcc aacaccgaca cctgctgata aaatcgcata tggtcagttt 50341 atgaaatttg aatccagcaa ctaccgcgga tattatatac gggttaaatc gttttccggc 50401 cgtatcgacc catatgtgaa tcctgtggaa gattccatgt tcaagatagt tcccggtctt 50461 gcagacccaa gctgtatttc tttcgagtcg aagacttatc cgggatatta cctcaaacat 50521 gaaaacttca gagttattct taaaaaatat gaagataccg atttattcag agaagatgca 50581 actttcagag ttgtaccggg ttgggcggat gaaaacatga tttctttcca gtcatataat 50641 tatccttaca gatatatcag gcacagggat tttgagcttt acatagaaaa cataaaaacc 50701 gatcttgaca gaaaggatgc aacatttata gggattaaag ttgattagca tatttcggga 50761 caaaggaatc tgttttgagt ggcggaactg attggattaa aagtcaggta attgtacctg 50821 tttttggcac tgcaagtata attttaccgc ccgcacaata taatctataa agcagacttt 50881 ttattgcggg tggactatga acctttacag gctgacaata atcatactta tcgcattggt 50941 attggccatt aatataaaat ccataaaaac cataaaggtt atttacctta aatccctcgt 51001 gcttccttta gtgtgcataa ctttcatcct tatgctcatt attttttccg acaccgcggt 51061 aaaatccgcc ggcagcgggc ttaacctgtg gtttaatgtt gtatttcctt ccctcttccc 51121 cttttttgtt gcatccgaaa tcctttacag gacagggttt attaaagcca taggaatact 51181 tttggaaccc ataatgcgtc ctcttttcaa tgtgcccggc tgcggctcct ttgcttttgc 51241 catgggaata accagcggtt atcccgtcgg tgccaaaatc accgcaagca tgagggaaga 51301 aaaactcctt agcaaaacag aatcggaaag gcttttgtct ttcaccaaca actcaggccc 51361 cctctttatt atcggcgccg ttgccgtagg catgttcaaa atgcctgagc ttggacttct 51421 gcttttagcc tgtcacatcc ttgcaagcat caccgtggga attctttttc gcttctatgg 51481 cagaaacaat aagaaaatca agatgaaaga cgacaaaaat ctctggagaa gatttaaaaa 51541 agaattgatt tatacctgca aacaagaatt aaaccccgga acaatgctgg gagaagccat 51601 aagaaactcc gttaacgtgc tgctttccat tggaggattc attactcttt tttcagttat 51661 tattaatatt ctgattgaaa tcgggtttat atcctgcctg gcgtctttta tttcgccgtt 51721 tctgtcaccc tttggaataa gcagagaaat agttttggcg gtattaagtg gtttttttga 51781 aatgacaaca ggaacaaaca tggcaagcaa agcggcaaac gcaaccctcc agggacaact 51841 tgcagcggtg agcctgttgc tcggctgggc tggcctttct gtgcattttc aggtttacag 51901 cattataagc cacaccgata taagcataaa gccttattta tttggtaaaa tgcttcaggg 51961 agtgtttgca gcaatttata tatcaatagc aatgaaatta ccgtttacgg cttctttgac 52021 agcaaaaagc gttcttagtg ttataacacc tttttcagac tttacatggt acaatgcctt 52081 catatattcg gctcagaatg tgtttatttc atttttgatc cttttgattt tgacggcaat 52141 atcacttata tttcatttta taaaacacgt atgcaagact cttttgaaac gttccgtatt 52201 ttaaaacagc ctgaaacttt ttgcctctac ttcagttctt ccctgttttc ccttattacc 52261 tgcaatgttt cttccaaaat ttgttcaacc ttgcttaaaa tactgtcggc atactccttt 52321 gttccaagcc ttatttccct tgcatttttc tgggcattgg aaataatttc attggactgt 52381 tcgtatgctt tttttgtaat ttcatgttcg tcaatcaaag atgcaatctt gttctccgca 52441 tcttttatta tattattggc ttccttctgt gcttcaagga gtatcctctg cctctcctcc 52501 tttatccatt ttgcctgttt aatgtcgtcg ggaagcttta acctgatttc tttgataatc 52561 tcaagtattt cttccttgtc caccaaacac tttccagaaa acggcacagt aacacttttt 52621 tcaacaaggt cctccagtgt ttcaagaatt gaaagcattt ccatatttat ccctcccagg 52681 gtttttggca atcttacctc cgaaacttgt ccataatttt atcttttata caatccggca 52741 caagtccatc aatgttgccg ttgtggcgtg caagctccct cacggagctg gaacttaaaa 52801 aagagtaatt gatattggtc atcataaaca acgtctcaat gtcggaatca agatttttat 52861 tcaaaagggc catttgcagc tcatattcaa aatccgaaac ggctcttaat cccttaataa 52921 taaccttgga attctttttt ctcataaaat ctatcaaaag ccctgaaaaa ctctcaattt 52981 ccacattatc tatgcctttt acggcacatt ttaacaaatc aactctctct tccagggtaa 53041 aaaccggatt cttgctgctg tttacaagta cagcaaccac aagtttgtcg cataattttg 53101 cagctctttg aattatgtcc atatgcccgt ttgttaccgg gtcaaaactt ccgggatata 53161 caaatacgct cactcttcat accttcttac cttaaagatt tatttgtcaa gtcacacaga 53221 tttcaacctg taaaaggata cagcagtatt gccgtatttc tcccaacgat acctctcaag 53281 tccgtccact tcttctggaa ccgcgtcttc tatatcatgt tccgcaacaa ttattccttc 53341 atgcacaatt atatcatttt cagctatgct ttttaacgtt ttttctacaa gtcccttgcc 53401 gtatggggga tcaagaaata ttatatcaaa ttttttgtta tttttcgaaa atttattcaa 53461 tgtcacaaaa acgtctccgg caataacagt ggctttgctc tcaagctttg tatgaacaag 53521 gttttccttt attgtaaaaa aacactctct gcttttatcc acaaacacag cagaatcggc 53581 acctctgctc agcgcttcta tcccaaggct ccccgtgccc gcatatatgt ccaaaacatt 53641 tgtacccggt acaaaagcag ccaaaatgtt gaacacagct cccttaacct tgtccgatgt 53701 aggccttgtg gcaagccctt ttatcgtctt tagcttatgc ccctttgctg ttccggatat 53761 aactcttaaa ataacaaatt cctccaattg acattgaata ttatggttac aatgatattt 53821 tatattatca tacttaattg tcaatcataa ttcgactttt aattcaaact tacgtcatgt 53881 attttttcta tgaatttctc ggcaattttt tcctttaact ttagattttc ttccataaat 53941 aagtttcgat ctctttttaa aatttcctgc gccgcttcct gcgctttttt ttaatatttc 54001 catatctctg taaagatttg caattttaag atcgggcagt ccatgctgcc ttgttccgaa 54061 aaattctccg ggccccctta tcagaaggtc tttttccgat atgacaaaac cgtctgtggt 54121 ctcctgcatg accttcattc tctcttttgc aatctggctt ttgctctcat tataaagaat 54181 gcagtaggac tggtgcggcc ctcttcccac ccggcctctc aattgatgaa gctgggcaag 54241 tccaaacctt tcggcatttt caacaaccat cagtgttgca ttgggaacat tcactccgac 54301 ctctacaact gtagtggaca caagaatgtc aatttcgcct tttaaaaact tctgcatgac 54361 ctcttctttt tcgccggcag gcatctttcc atgcagcaaa ccgactctaa aatctttaaa 54421 atcttctttc gctatctttt ccgcagtttt tagagctgat tttgcctcta tttcatccga 54481 ttcatccacc agaggacata ttatataagc ctgtcttccc tcaagtatct gtttttttat 54541 aaaattgttt attctctgcc tcatgctgtt gtcaaccgca taggttttca caggctttct 54601 tcccggcgga agttcgtcaa ttatcgatat gtccaaatcc ccgtaaagga ttagcgcaag 54661 agttctggga atgggtgtgg cagtcattac aagaatatcc gggtttattc ccttgttgga 54721 aagcatagcc ctttgtctta ccccaaaacg gtgctgctca tcggttataa ccagcccaag 54781 ctttgaaaac ttgacctttt cctcaataag tgcatgggtg cctataacta tattaacctc 54841 gccggattca atttttgaaa gaatttcact cctttgcttc tttgtctggc ttcccaccag 54901 caaggcaaca tttatcccgt gctttcccat aatatccttt aacgattcat agtgctgctt 54961 tgcaagaatc tccgtaggaa ccatcattgc cccctgatat ccgctcttta ccgctttagc 55021 cagcgccaga gccgcaacaa tcgtcttgcc ggagcccaca tccccctgca caagcctgtt 55081 cattacacgg ttgctttcca tatccttttc tatctcttcc cacaccctct tctgggcatt 55141 ggtaagcgta aagcctatgc tgtttataaa gtcaaccatc tcttttcggt ttggcgcaaa 55201 agcaatacct tcttttccgt cggaaagtac agtcttgacg ctaagaagtc caagctgcaa 55261 gagaaaaagc tcttcaaaca ccagcctgta cctggcattt tttatatccc cgtcatttcg 55321 tggaaaatga atattggaaa aagcataatt tatatcgcac aggcaatact tttttctcac 55381 ccataaaggc aatacatctt ccaaatttcc gtcaacaagt tccagggcat tttgcattac 55441 ggttctgatg gtgttttgtg taagattcgc cgttgcatgg taaacgggca caattttcat 55501 tgtattttta tgttcttcct tgcaggcttt ctcataaacc ggattttgca cctccagggt 55561 tttgtatccc cgtacaattt tgccgtaaaa aatatagctt tcaccgacgg tcaggacttt 55621 tttaatataa ggctgattgt accacgtcgc tattatggtt cccgtatcgt cttttatata 55681 tgcctgatac agagtcaatc cctgccttat ttttctttcc gtgacctttg acataataat 55741 gccctcaaag gtacagctct ctccctcggt aagctgacat atttttttaa tattgcttct 55801 gtcttcgtag tcatagggaa aatgggttat caaatcttct atgctaaaaa tgccaagttt 55861 gtgaaacagt tttgctcttg catctcccac acctttaaca ttctttattg attttttcag 55921 aatttctttc atatcgccgt tcataactta gctcatccct tgcaaactgc atttgataca 55981 agcaatcctc tgatacaaat tccaatacaa aaataatttt aatatatctc agtctttttt 56041 gccatatacg caaaaaaaac ttgcgaacag tgcaaactat atgttaaaat aggtattgtt 56101 ttcaatgcta aaaaaaagac agcagattaa ttgctccaga tttaaaggag gtgtaatata 56161 aatggcaaag tgtgatatat gcagtaaaga tgttcttttt ggcttgaagg taagtcactc 56221 caacaggaaa accaacagaa catggaagcc aaatatcaga agaatcaaga ttatcgagaa 56281 cggtacttcg aagacagcaa atgtctgcac aaggtgtttg cgttcaaaca aagttacaag 56341 agcaatataa caattttatt caatattaaa aaatatttaa aaaacagcga aaaagtgtac 56401 cacatgcttc ttagaaagaa tgtgatacac ttttttattt tttctgccaa ttatcagaca 56461 agcttaaccc attctaagaa cctttcttaa aatgcttcca aaaaactttg gcatttttac 56521 caccaatatc ttcatataaa aacactcctc cccggtaaaa cgctcctcaa tacatagtat 56581 attcacaatg ccgttttttt gtgaaatctt tactttagct tgcctgtttt accacttttt 56641 tgaccacttt gaaaattaca gcggccgcca gtgcaaataa aaatgtcggc accagggcaa 56701 tgtccataat tttgggcccg aacgtattaa aatagggcat ataggcacca atccaggccg 56761 ccggaagcgc aacaacacaa gcttcccaaa tatcctgcgg cgtctgcctt ataattatgt 56821 tatttcccag ccatcctgca atcaaagcaa ttacaattgt aacaataaat ccacccatca 56881 ctgactcctc ccaaataaaa aattagactt catccaatta ttatttccat aaaaatgttt 56941 tatttgctaa atgactgaat aaaatatact atcaaaaatt attttaactt ttcagggggg 57001 atttaaaatt gtacataatt tttattagca actataaaag aaaacttgta tatctttttg 57061 caattatcgg gctttggatt ttgctttttt ttcttacggg attattttta aacaactctc 57121 ttaccatgaa agttacaatt gaaaattacc tgtctttttc atgtccggtc aaatacgaca 57181 ttgacagtgt ttatgtaaat gaaaaaatta aagaaagttc gatagaaact gccaacaatt 57241 tcaaaaagcc ccgtgccgaa aagttctcaa cttatgaatc aatagaagga ggattcagtt 57301 tcaagtatcc ttccgctttt tcgctgaatg aagaggaatt tgaaggctct gaaatactct 57361 atcacgttgg ttttaagaat aaaaccaaca cctgccatgg tttcgtgcag gtatggaatc 57421 ttccttatac cttaaaagaa tttcttgcaa aatcaaaatc agcttcagaa caaaaatata 57481 aacaatttga agaaaaggaa gtcttagtca actctattcc cggcatcttc tgggattata 57541 cggtcataac gcaggacaac aaaagcttta aaggcaatga agtatttttg aagaaggatg 57601 acaaaatgta cagaatcagc tattttgttc ccgaaaattt atggaacaaa aaagaatcca 57661 aattatttga aagcattgtt ttctcattta aaatcaaaac ttaaagcaat cagaagcaaa 57721 ccattaaaag aaaagcgtat ttttaaaaac accggaaaaa tactatcttg gtatcctaac 57781 gcagtttctg ccggattctt tggcgtcata cagcgcatta tccgctgttt tcaaaagctc 57841 tgactcagtg tttgcaaact caggatagga tgaaactcca aagcttacag taactgaggc 57901 ctccaccagt tcatctttta tcgtcgtctt tgcaacaata ttcctgagcc tttcgacctt 57961 gtcatacgct tctttaacgc ttgtcctcgg aagcaatatt acaaactctt ctcctccata 58021 ccttgcaatt atatctccgc ttcgcaggga ttttttcata agatgggcaa tatgttttaa 58081 aactttgtca ccgaacagat ggccaaaggt atcgttaaaa cgtttgaagt ggtcgatgtc 58141 cataatagcc agcgacaaat cataattttc ctttttggcg ttcgcaaatt cctctctgag 58201 cctttcctgg aaataaagcc tgttgtatat tcctgttaga ctgtctatgg tagccatttc 58261 atgcatcctc tggtacaatt ccacattctc catcgcaatt cccacttgct gtcctattat 58321 gtttaaaagt ctcagattgt tgtcatcaaa agcattgaaa tacttgtgct caataagtac 58381 caaaccaaat ttctttgcct ttgtgataag aggtacacac agaagagaat gtatgcctct 58441 tccttcgaca aaaggatatt cctccatatc cacaaaattc tcaagtatgg gttctccttt 58501 ttgcaatgca tctaaaagtt tttggcagtt aatattgtca tttaatataa taagctcttt 58561 tcggtttgta atgtttgtgg tatgtacctt gagtcttcct ttattttcat cataaagaat 58621 tattgtggaa ctgcttactc ccataacccc gattataata tcattaacgc tctttaaaag 58681 ctccctgaca tcgaatatcg agcttatggc ctgggttatc tgctgcaatg tgaaaagctc 58741 cgcaaggctt gtcataaatt ttttgttcgc ttcttccagc ttcgaattgc actcttttaa 58801 tttatcattt tgagacttaa tttcttgctg agcggccgaa agctgctcgt atttgtttgc 58861 aatctccatg aacagcttct tgttctgctg ctcgttctca taattgtctt tgtacagcat 58921 ccagcaaaaa accgcaaaca gaaaaaagcc aatatagata gaaaacatgt ctataatatc 58981 cttcggcgat tcaaaaagag ccgcaaaccc attttttatc taaagggaat ggaaataaat 59041 actttaaaat aatattccac aaaaaagcat atcccaccat tgcaaaggaa aacttttttt 59101 ccgcataaaa actggtaaca aggataagga acatgagcat aacatatccc cattccccgg 59161 tcccggaaaa aactatgacc gacaatataa gcggcacttc caccagtctt acggtgtgat 59221 aaactttctt gcggaaaaac aaattgtttc tgacaagaaa atacttggca atattgacca 59281 aaggtataag taaaaagaaa gaaagcttga tcacagtacc cggatatgtg ttttgaccgg 59341 attgcatgcc aatatcacag actacaatat gagcaacaaa gaccatgatg aaaatccacg 59401 taaagcgaat gaacatcagc tcatatttac tgaccttttc cacaagccca cttccttttc 59461 agattggatg tcttttctga cttgcatcat tttaaatgct ctttaccata gtcacaatag 59521 tcaataattg cgcatttatc gcattcaggc tttcttgcct tgcaaaccgc ccttccatgg 59581 tagaccagct gatggcaaaa cagcgaccac ttttctttgg gtacaatctc catcagttca 59641 aattctatct ttttaggatc atcggtattc accaatccaa ttctgttgct gagtcttttg 59701 gcatgggtat caaccacaat gcccggtatg ccgaacgcat cacctaaaat aacgtttgcg 59761 gtctttcttc ccactcccgg taaagtcagc aaatcctcca tattgtcggg aaccttgccc 59821 ccgaattttt cgacaatgat tttgcaggtt tctttaatat tttttgcttt gttatggtaa 59881 aatcctgttg gctttatatc ctgctccagc tcttttaaat cggcattggc aaaatcccgg 59941 gcatctttat atttcttaaa aagcgtcttt gtcaccacgt taaccctcgc atcggtgcac 60001 tgcgcggcaa gctgtgtgga tatgagcaat tgaagaggat tctcataatc taaagtacac 60061 tgggcatccc tgtacaactc gtcgaaaatc tttattatct ctttcacttt ctcttttttg 60121 tccatcatac tgtcctccac tatattataa cagataagta catcaattgc atagcaaaag 60181 attcaaaaat tatttatttc tgtatcacgc tatagaaaaa agtccagtaa aaccggactt 60241 ttttgcttaa tatagaaata aatatgcatt attttttctt ttttgtaagt ttcatataca 60301 aatctgaata tttgcttgcc gagttgttcc atgaataatc ggcactcatg gcacgcttta 60361 ccatagcctt ccattcatcg ggcttttcat tgtaaaactt tatcgcccgc ttgacagtct 60421 ttaacatatc ctttgatgaa aactcttcat atgaaaaacc gtttccgttt ttcttgtcct 60481 tgtctatatc aattaccgtc tctgccaatc ctcctgtagc ccttactatg ggtatggtac 60541 catacctcag gctaaacagc tgcccaagtc cgcaaggctc aaatctcgac ggcataagga 60601 acatgtcact gcccgcataa attcgctggg ccaaaggcgc attaaacccg atatacactc 60661 ccactttgtc aggatacttt tcctgaattt tcttaaatcc tgtctcataa tattcatctc 60721 cggctcccag caggacaaac tgaatatcct ccttcatcat ctcgtcaatt tcatccatta 60781 taaggtttaa gcctttctgt ccggtcaacc ttgatatcag cccgataaca ggcacatctt 60841 tttttggaag tcccatttcc ttctggagag catatttgtt ttccactttc aattcaaatg 60901 tctcaacatt atagttttta taaatcgccg ggtcggtctg gggattgaac acatcatagt 60961 ctataccgtt tacaataccg taaaggtctt tggaccgttt tctcagcaaa ccttccagcc 61021 tctcaccgta cttttcggtc tgaatttctt ttgcataggt ctcacttacc gtggttataa 61081 tatccgcata aaccagtccg gctttcataa agctgaacat tccgtaaaat tcgacttttt 61141 caggtacaaa tacttcatcg gaaactccca tgatgcctaa aacatccctt gaaaaattac 61201 cttgatactc aagattgtga attgtaaaca tggtctttat gtttttatag aaaggataac 61261 ttttatactt ctcatttaaa aacatgcaga taggtcctgt atgccagtca ttacagtgaa 61321 ttatatccgg tttgaagtct attttcggaa gcatatccaa tgttgccttg cagaagaaag 61381 caaatctgtc tgcatcatca aaataacaat atatcccgcc tctattaaaa tagtggtaat 61441 tgtccacaaa ataaacaggc acgttcaaat ccttaccgtc tgctttgaaa ctgatttctc 61501 cttcccgtac tatacaagtt gcctgccttc ctcccatatc caccggaaaa tccgtcacgt 61561 acctcatatc agcatctatc tgctgatact tcggcattgc aatcctaacg tcatatccca 61621 tggaaaccaa agcctttggc aaagaacccg ctacatctgc caatcctccc gttttagcaa 61681 atggagcaac ttcaacagaa acaaacaata ctttcaaatt atgattctct ctcattttat 61741 acctccgttt ttgtgttttt tggtaaaacg aaataatata ttctctatag tttaatcgtt 61801 aaaattacta ctaaatatta ataatatcca ttttatcctt gtgcaaaacc aaaacattcc 61861 gccaaggcct ttttatcaat aagttctacc ttcatctgcc atcatcagaa gcaaatcagc 61921 aatttcggga tcaaattgcg ttcccctgca tctttttatc tcctccaggg ctgatttcat 61981 atccatgccc tttctgtacg gtctgtcact tgtcatggcg tcgaaagcgt ccgccacaca 62041 cattatcctt gcaaaaatgc aaatttcttc tcctttaagt ccgtaaggat atcctttccc 62101 gtcatatcgt tcatgatgct gcagtatacc gttcaaccca ttctttaaaa attctacatc 62161 tttaagaata ttatatgcaa taatcggatg cttctttatt tcttcaaatt cttcatccgt 62221 caattttccc tgcttgttta atatactcgc cgaaatacct attttcccta tatcatgcag 62281 tatggccgca taccttaaat ccttgatttc ttcctcagac agtttcattg cccttgcaag 62341 ttcacaggat atttccataa ccctctggca atgccctctt gtgtaaggat cctttgcctc 62401 gatggaattg gcaagacaca taaccgtctg aagatagcca tactgaatgt tgtcaaacag 62461 tgtcatcagt tcgatatttt tctgattaag ctcctctttt gttttgtcca attccttgat 62521 ataactgttg agctcttcat tgcttgccgc agcttgttca tacaaggctt ctatttcttg 62581 tttctggctg tatatattat taaacatttc agcatttctg atacctatgg caacataacc 62641 cgcaagactc tttaaaaaac ttaaatttac ttccgaaaaa gctcctgttt ttgaactgcc 62701 aatgaaaatc gcgcctatca attcatccga aacatttaac gaaattgcca taatttcacg 62761 tttttcttcc cttaaaagcg tttcaatttg cggctccgaa aaaggattac tctttgcaag 62821 atttctcaca tactgttcat aatcgatatt ccccgcttct ttcaatactt gattgccaaa 62881 ctcatagtta aacgccggct caaaagattc tttgtcaaca aaacaaacat aataccattc 62941 acatctggta attcttacca gttcattata tgtatgttcc attattactt ttacatcaaa 63001 agtagacgta atgaccttcg acacttcatg aagagagtca agttcagctt ccattttttt 63061 attctttcgt tgtttattaa tatttcctga taattctttt tattagaaac aacctttgac 63121 atgtaatcaa ttaatgcaag tattaaagca aatcccatga taatggcaaa tctgaagtct 63181 gaagtccggg caaatccaac tgccgagaaa aagagtacgg cacacaggaa aaaaaactta 63241 actatcaata tgtacacaga tttgttttgc ataaattacc tccgctttgg gtaatattct 63301 gcagacaaga ccgatttgac acttctattt atttaacaat atgattattc tatatatcgt 63361 cataaaaatc cttccgttta atagaattta acataagtca aaacataagg taaaaaataa 63421 gcggctttta caagccgcct ctgatatgca acgctttatt tttgctcatc caacgtcact 63481 tcaacggtaa tatcttttcc gtccctgtgt attttgagtt tcactttgtc tccgggtttg 63541 tatttgttct tttgttcttc caattcatca taattcttta ctctcacgcc gttaaactcc 63601 gtaattatgt catccttttg aataccggct ttgtaagccg cactgaatat ttcaacgttg 63661 taaacaagca ctccttcagg aagtccgtaa cggtctgcta tttccttggt gtaaccgctg 63721 tttatctgta tgccgaggga cggtcttcct cttacatact tgtactgaat aaggctgtcg 63781 gttatttcct ttgctttgtt tacaggtatt gcaaaaccaa gtccttcata gccctgtccg 63841 ccgatttttg cagtattgac accaattaac tttccttcgg cattaacgag agcaccgccg 63901 ctgtttccgg gatttattgc ggcatctgtc tgtatcagct tcagttcctt gccgtcggtt 63961 ataggtattg tcctgttaag accgcttatt acacccacgg taaccgaacc catgtattca 64021 agtcctccgg gattgcctat ggcaactgca agctcaccga ctcttatttt atccgaatcc 64081 ccgaattcaa tcacgggcag gttggttgct tcaattttaa gcactgccaa atccgtcttt 64141 gaatccgttc ccacaaccgt agctggatga ggtgtgtccg gatcacttgg caaaataaca 64201 ttaatacttg cattcggaag tagagtgttg gttcttccgt tcaaagccga ttcaataacg 64261 tggtagtttg tcattatata tccgtcactt cttattataa tgcccgaacc ctgggattct 64321 gtgtctcttg gtgtaaagaa ccagaaatca ctgatgcttg tcgttgattt tacacttata 64381 cctacaactg aaggtccaac cttttcagct attgcaacca ccacagaaga atcggcgttg 64441 ttctcaatga caactttttt ataataatcc gtatccactc ccgatgttgc gtcattcgaa 64501 ccgttctgaa cattggtgtt tctgaaaatg gactgaaccg aaggactgag ggccggaact 64561 ccaaatacaa agaaacctcc gactatcgag ccgcccaata tggaactcat aacagcaaca 64621 agtatcatct gcagtaaaac actgttttta cgtttttttg gctttgtata gctttcagaa 64681 taatatgaag ccgactttaa atccacgaaa cttccttcat aagtcttttc attttccact 64741 cgtttatctg caacgcccac ggcagcattt tcaatcacat tttcgccaaa accttcggca 64801 gcattttcac cgacatccgc gtcaacattt tcaattatat tctcagctgc atactgtgct 64861 gcattttcaa ccacatctcc atttatattt gcatcaacat tttcgccggt tgtattgttt 64921 aattctccga aactctttat ttcattttct tcattgctaa aaccgttata gtttaattca 64981 tccataccca tctctccttt cgacgtattt tattttgttg attttattat agagaaggaa 65041 ttttaaaaac ttatgaataa attgttaaga ttgcttttta tatatttttt cgtttttatg 65101 ctttttcatt gcttcctttg tccaaagtaa aataaaactt ggttcctttt ccgacctcac 65161 tctcaaccca gatttcctgc ttgtggtcgt ttattatgtt tctgactatg gcaagtccaa 65221 ggccggcacc gcctttttct ttgcttctgg atttgtccga cttgtaaaat ctttcccaga 65281 taaggtcaat ttcattcctg tcaattccta tgccgttatc ctcaacacaa acaagtacct 65341 tgtttttgta acttgaggtg gatactttga tttttccgtt ctgctgaaca aatttgacag 65401 cgttgtgcat aagatttata agcactctct caatggagtc aatatccgct tttacataca 65461 tatcctcttc ttcaaaattt gcctcaacct caatgtcctt ttgtgttata aagttttcaa 65521 gctttataat gcatcgtctg ataagttcat tgatattaaa gttaaccgga tttatagtga 65581 tttcaccggc ctccattttt gcaaggtcaa gaagatccgt ggtcagcctg ttgagccttc 65641 gtatttcatc ccggacaatt aaaaggtaat ccttttcctt ttccggagga atggttccat 65701 ccagaattcc ttctataaac ccatgtattg aagtcatcgg ggttctaagc tcatgggaca 65761 cattggcgat aaaacctctt cgcatgtttt ccagattctg aagctctccc gccatgttgt 65821 taaaacttct tgcaagctca cctatctcat cttccgatga aatatcaagc ctttcgtcaa 65881 attttccgct tgcaattttc tttgcagcac tgttaatctt tttcaaaggc cttgaaagct 65941 taagtgaaaa aatataaatc agtactattg atattattat ggaaatgaca acggcaaaaa 66001 taaagaactt aaaaacactg cttcttgccc tctgtacctc aggaaccggc gtatgaaggt 66061 aaacagcccc gagaattttg ccgttatatg taaacggctt tccaatagtc agccacgata 66121 cattcgtgtc cttaaacagt ccgtaaaaat ctcctatttc tttgaccatg ggcacactac 66181 cgctcataac gtctttatat tgtgccgggt tttgcagttt aatcttgccg gtgtcgtcgg 66241 taagcttttg gactatttcc cttaccaccg cctgattacc cttgataata ccgatttctc 66301 cttctgtgga cacaatccat atgacagtgc ctgtactttg actttccctc tcaagggcgt 66361 tatccagcat tctgcggtat atttcctccc agaatgcaaa catgggattg ttatagttat 66421 tgtaataagc agtcaaataa tcgttcagca tactgtttat actgtccgca gtgtcactta 66481 ataatttttc cttttcctcc gaggcaaaat ttccaagaaa aatataaagc atcaccccgg 66541 ttatggatgt gcttacaagc aaaatggcaa taaacagggc aacaatcttg ctaaacagag 66601 tttttagcat tatttcacct caaatttgta tccgacaccc caaacagttt taagctgcca 66661 gttttgtcct tcactgtcaa gcttttccct aagtctcttt atgtgaacgt ccacggtcct 66721 ggaatctccg taaaagtcat agccccagac ctgctctata agttgttccc gcgtaaaaac 66781 cttattgggg tttgaggcaa gaaaatacag aagttccagc tcttttggcg gaaactccat 66841 ctctttgccg tttactttca aggtataatt ggtcttgttt ataataagat tcgggtatac 66901 tatctcttgg acatcactgt ccttgtgctc atatcttctg agcaccgctt tcactcttgc 66961 cacgagttcc ttcggttcga aaggttttac aaggtaatca tccgcaccaa gctccaaacc 67021 cagcactttg tcaaaagtct cccctttggc cgaaagcata atcaccggaa tattgctgat 67081 ttttcttatc tccctgcaaa cctgccatcc atccgccccc gggagcataa tatctaggat 67141 aacaatgttt ggagcctcgt ttctgaatac ttccagagcc ttgctgccat tgtataccgt 67201 tacgacctca aaaccttcct tttccatata cagccttatg agctcacaaa tatttacatc 67261 atcatcaatt acaagcacct tggttttgtt actcatatac atcaccccaa tagttttaat 67321 acgcagggca tacagagtcc cacatgaata tgaacctcac gtcaatttaa tatttcgtgg 67381 cggaaaggca aactgtttag tactatgttt tgtattttta tttcctcctg cagttttttc 67441 tgttcttcct taagctcgtt tatagtattt gcaagtctct cattttcttc aatcagaact 67501 ttaatcatat ctctaatctc attgatagcc tgcctgtcct cctgtctcat aaacatattc 67561 cccctaataa ttagtaatgt atatttacga aaaaccaatg catataaaat atcatccaat 67621 tgcattgtca atattaatat aagtaataca agaacaatat atcagcatgt attattttgt 67681 tactgtatat tatagcaaat ttattgtttt gtgaacacca aatttacatt ctcaagctgt 67741 ttctgccata caatatctgt tgacttgccg acggtgttat gataagtttt aagtatgtgc 67801 tattattata tatagtagcg gtattttacg ttttctggag gggtaaaata tgggtcaact 67861 taatattgtt accgttttag tatctctggc ggtgcttgtt gtcattatcg ctttgttcgc 67921 atatataaac aacaagaaat cgaattcctc tgcatccgac aatagccagt cttctgctga 67981 tttaaccacc gtttccgaca aaaccgtaaa ccccaccggt aatctttccg atgacgatgc 68041 cctggttgcg gtactgactg ccgcggtact tgcaagtatg ggaaacagac ccgatattaa 68101 aataagagta acctctttca gacgtacaaa tgagacatcg ccaatctgga acaccgtggg 68161 aagaaaagag tatatttccg gcaaactcta attcttcagg attgtccatc ttttaaaagg 68221 gtttgtattt ttgttaaaat ttagttgtat gctgtgttta ggaacaattt catggcattt 68281 tcgcctaaaa tatttttttt ctcttcatca tcaagtttca tgctcatgaa tctttttaag 68341 tcccatgccg ggcttcccca tgggtaatca gagccaaaga ccaccctgtg ggctcctatt 68401 tcgtttataa caccctcggg tatgctgtca tcaagccagc tgggcttgtt tgtttctctt 68461 atcggcggat agcctgaaat aacaatggat gtatcaaagt aaacattttt ataggtcctg 68521 gaaagcctta aaacatcctt tacattaccg tcagccatat gggtaagtac gaaagaaata 68581 ttttcataca ttgcaatgag cggctccaaa gtttccacat cggaaaaact gttcagtctt 68641 gcatttgcca ccctgccgca atgaaatact atcggaaaag caatgtcatt gcaaaattca 68701 tataaacctt ttaatctttc atccctggga tcaaatccct gagccatggg atgcagcttg 68761 attccttttg ctccgtccga aatatattct tcaagcaggc ttgtaaatga cacatccatg 68821 tcaggatgaa aacttaccaa aggtatcaga tttggatgtt tccgtgcttc ttccaaagtc 68881 catttattgt tggcatgaag aattttaacc ggagcaaaat tggccatgac ggtataatct 68941 ataccctcat ttttcatgtt gtttaaaacg tcctcaatag tccctgttcc cgggttttca 69001 aattctatat tataaatttt gttaaaagac ttcagtactt ttaaagaaac ctcttccgat 69061 gaaaaagtat gaacatgtcc gtccacaatt gtaaaattgc ctatcatttc ttactactcc 69121 ctttgcatct acagacaaat ttttctcttt aacttttctt gtaaccgtat ccgcatactt 69181 ttgtcataaa gtaattatag attattatta ccgtcaaatc aaataataaa ttttatatcg 69241 ccaattcttt gcatccgctt taaagtctgt gctataatta tatggttaaa atatcataaa 69301 aaaataaaat aaaagttaaa aggaactgat tttatgaagt acatattgat tttaggagac 69361 ggaatggcag attacccaat ttctcaactg aataataaaa caccgctgca atatgcaaaa 69421 aaaccccata ttgattttct tgcccaaaat gccgaggtgg gtatggtaaa aaccatcccg 69481 gacggtattc cgccgggaag tgatgctgca aacctttctg taatgggtta caatccgagg 69541 gtttattata ccggtcgctc gccccttgaa gcggcaagca tgggtattga cttgtcagac 69601 actgatgtgg ccataagatg taacctggtc acactgtcag aagatgaaga atatgatcaa 69661 aaaaccatga ttgattacag ctccgatgag atatcctcag aagaggcaaa agagcttatt 69721 tatgagataa acaggcattt taaaaatgac agtatatgct tttatcccgg cataagttat 69781 cggcactgca tggtatggaa gaacggctac acaggattaa agctcactcc acctcatgac 69841 atactggaaa agaaaatcac caattatctc ccttcgggag aaaacactga aatattgctg 69901 gacatgatga tcaaaagcta tgatatttta aaagatcatc ctgtcaacaa ggccagagtc 69961 agcagaggac ttcggcccgc caattccata tggctttggg gagaaggcaa aaaaccaagt 70021 attccaaaat tttacgacaa atacaaacta aacggctctg ttatttcagc cgttgacctt 70081 attaagggta taggcatttt ggcagggttt agaaatgttg aagttgaagg tgctacagga 70141 aacattgaca ccaattttta tggaaaggct caggcagcgc taaaggagct tgaatcaggg 70201 caggactttg tatacctcca tatagaagca cccgatgagt gcggccacag acatgaaatt 70261 gaaaacaaag tcaaatccat tgaattgata gacgaccgta ttgtcggtcc aattatagaa 70321 gggctcgaaa agtatgacga ttatagaatt ttaattttac cggatcatcc gactcctttg 70381 tccttaagga cacatactgc cgagcctgtt cctttccttc tctaccaaaa aacaaatccg 70441 aaaaagtccg gtgtaaccgg atatgacgaa ttgcaagcag ctaaaacagg catcattttt 70501 aatgacggtt acaaacttat ggaccacttt atattggatt gacaaatcgg ataatttctc 70561 tatggtttcc ccaatcgccc gcaaggtaaa ctttcgggcg gtttttctat gtcagaacgg 70621 tatcttcaac aaacaaagtc aggtcttcca aaaggtttat atctcctatt ataccttctc 70681 tattataaag ccttaccaca ggcctttgag gacttcccat gttctgccgc accacaacgc 70741 cgtgcaaacc gttgctgagt tttacggtac atccattagg ataaaacact atggtatccc 70801 gaaacacctg cacaacgtcc gggtcaagaa tgcttcctga aacagccagg acaacctcaa 70861 atgcctgatg aggcataact gaaacaccgt tgttttctct tccgtgcagg acattgtcgt 70921 agtagtccgc aacccgtaca attcttgcat aatcggaaat attggttcct ttcagttttc 70981 ttggatagcc ggttccgtca aaattttcat gatgctcgta acataccttt gaagagttca 71041 aactcattcc tctgagcttt cgcattattt caaagcctat ctcaacatgt tccggcttct 71101 cctccgcaca gttttccctt cccaggtcat gtatcaaagc tcctgcgaca agatcacaaa 71161 gctggttgaa tgtataggac aatcggtttc caatgtaggc agttattatc gccacattga 71221 cactgtgttc aacaacatac tcatcaacaa cgtccgtgga aagcatgctt atgcctctgt 71281 ctctgtactc tctggcataa tcaacgattt ttcttgcggc atcttttatg gcaaattcat 71341 ctatttcctc cgaattatgt atcttcgtgt atgcactttt cagcaccttg acaacatcat 71401 ttctcgtcgt aatgtcaatg ggctgggttg cctccacatc attaaatctg gcatcatcta 71461 tatagactct gtttattccc aattctttaa atttctctat gtagttttct ttaagaacca 71521 cgccggaatt taagatgatt tttccgcttg cagtaaatac aggccttgcc aattcatcgc 71581 cgggttttaa tgaatttaca ctgacaagtc tcattgacta cctccatgta agagtattta 71641 ttcggacaag gacctcctat ccaagccttt ttcaatattt ctcaaaagaa aagagtacat 71701 atttatgaaa ctttatgaaa ttggttttgt aaaataacat attcgacaaa aaaatatttt 71761 ttcctgttaa ctattaaaca aaaattcttt caaattaatt accaaaaata tatcaatata 71821 ctaaaaaccg tattcaatta agaccgcacc atataattcg atataccttt tttccttttg 71881 cgaaagattc agattccact tttcttccaa ataattatcg cctttgtcaa aaactattat 71941 cctgtttata acaattttaa ctatttcatt ggtaattcca ttatttgtaa tataattctt 72001 cagtttcgca atcttttctt ctgaagtcac aaactctgac tttcgtaaat ccaattgggc 72061 aatttcccgt tttatttcag aaattctgtt ttcaagcctg ttattcatcc ttaaaaaaag 72121 actttcggat atcttgtttt caagtctatc ctgataaaga atctcctgct gcttttgttt 72181 tgcttccatc tgttttaaaa gtttttccct caaagtttga taatcctccg ccgctccggc 72241 caagtcaatc ttttgcagta ttttgtttac catgttttca tcatccaaaa gctttgctac 72301 atcatccaaa acaacctcac acaaatcctt ttctcgaata ctgtggcttg tacacgccgt 72361 ccttccttct ttggcataac tgctgcaaat atagctcata ggcctgttat gccgctttct 72421 tgcaaacata acgcttccgc agcccccaca aaatatgctg ccgcgaaaca cgtgtataat 72481 ccctttgtgg ggaaccggtc ttgcattttt attattcctt attctttgaa tttcttcata 72541 ttcctctttg gaaacaatgg gttcatgggt attttcagta atcacccatc gttcctttgg 72601 cagacgtctg gttttcttgc ttttaaaact gattttctca cttactccct gtaccgtatc 72661 cccggtataa accctgttta aaagaatcct ccttatggct gtgggattcc agcggccatt 72721 ggaaggcgat tttacacctt cgctgttcaa tatgcctgcg atatagctgt atccatatcc 72781 ttccttgtaa aggctgtata ttcttcttac aatacccgcc tcttcctcgt ttacaatcag 72841 ccggttcttc tcataaggcg acttttcata tccaaaggga gcatgcccta tatattcccc 72901 tttttgtatc ttgaatctta aattggcccg gatttttctt gaaatatcca ggatgtagcg 72961 ctcgttgaac cacgtctcga tacctacaat atcgttgtct ttcaggctgt cataccttcc 73021 gtcgaaggta acgaccctta ctccgttctc ctctaaaaaa tcaagaaata aaagagtttt 73081 tgcattgttt ctcccaagcc tggacaaatc tttcagaacc agaagattta tttttccttc 73141 catcacatca cgtttaagct cgtagatacc ccttctctca aagccggatc cggaaacatt 73201 atcgtcaata taaatgcttt taatttcacc cagtccgttt tttttcacat aatcaacaag 73261 caggtctctc tgagtctcta tggtctcata gttttcctca ttgtcatccc tgctttctcg 73321 aacataaatt cccgttttgt aaaaagcctt cgctttatcc gttataccgc ctcacccctt 73381 tcctttttaa atcatcgaac gattttagac aaaaacagct gaatgatttt tgacaaaatt 73441 tcttcagcct tcttctgacc tgtgtatttt tttataatta cccttgattt cgaatccctg 73501 ttctccattg ccgaatacct cgtttgtgga tgctaactaa tatatatgcc aaaggaaaat 73561 ataataaaaa ttgtccggat tatttttaat ccggacaatc aaaaatagat ttcgttttcc 73621 gtaacaaccg catccatcaa tatatcatgc tcttccttcg gaatactcgg aaaaacctga 73681 atatcaaaag cgattcctat tttcaggcaa tcctttctaa cctctctcag aaaaatatcg 73741 tagtagcctg ctccgtatcc aattctgccg ccttttacgt caaaggcaac acccggtacc 73801 acaaccaggt caatatcttt tggatctatc ttacgggaaa actcttttac cggctctaaa 73861 ataccgtaag tacccggctt cagacaccct tcttggttcg tcaactcata cggaaatatc 73921 ttttttacac cgtccacaca atcaataaga ggcaaggcta caatttttcc aaggttcaga 73981 cagtgttcta tcaaaaacct ggtcattacc tcattcttaa aatccatata agccattacg 74041 catttactgt tgtaaaatcc gtccaaagat attaacttct ccgtaattaa tttacttttt 74101 tcaatgattt cttcttcaga aagccctttc ctaatattta gcgcttcttt cctaagctcc 74161 cttttgtctt tcacaaacat catcctacat ttctattact ttatttctat tatctgtaat 74221 caaaacctta tatttcccta actttcttaa aagattttat tcattcacgc aaaacacagt 74281 accaaaaaag caaaagccaa aattgtcaca acaaaggcaa taacagatga aatcaaaaga 74341 gcagctccaa aggattttct gtctttatcc tctccggcat ttataaacac tatggccgaa 74401 attactccaa aaagctgccc gattcccggc agaagatttg acaatgttac cataaaaact 74461 tttgtgccgt tactcaaagg ctttctcata tcattgtcat ttttattatt tacatatcta 74521 ccagtcacat caggattata aggtttggaa tcctgcatac ctgcctgctg aacctgaggt 74581 ttttgccagc cggtgttttg tccaaaatta tcacctgcat gttcgttcag accaccgagc 74641 ggagtttcct tattttccag catttctttc aatacaaaat cattctcatt ataatcatca 74701 tactggtcaa atgaaacatc ctgtcttgta aaatcagcaa cggaagtact gtcattaatc 74761 gttttctcaa acttgtacgc actgtcatca tcaacatcgt tatttatcgt atcaacaaaa 74821 tccaaagaac tatccgtcga atagttccca tccaagtcaa gaaaactgcc gcagtaagga 74881 caacgtttaa aatctgaggc aatattttct ccgcagaaac tgcatacctt cctatcgcca 74941 ataccgttca ttccaaatcc tccttgcaag tatactggct ctaaaccatc ctaacttatt 75001 attcttcaac acccgtcaaa atccttccac aatcacgcga aatttatttt atactgctta 75061 tgtaaattac acctgaggct gatattgttc aatacatgca tcctcaaatg tgcccatgtt 75121 cctgtatacc gacacggcac agtcaaaaat atgaaatgcc agtgccgcac cggtgccctc 75181 tccgactctc atctccagat tcagtatagg ttcaaatccc aacgcttcca taactttttt 75241 gcttccgggt tctgctgaac catgggaagg aaaaatgaaa tttttgacct tcggctccat 75301 ccttactgct gcaagggcag ctgttgcaga tataaatccg tcaataagga tcggaattct 75361 acatgccgct gcaccgataa agcagcctgc aaggcctgca atatcaaacc cgcccacttt 75421 tgaaacaacg tcaatagggt cgtttgcatc gggtctgttt aaatctatag cctttttgac 75481 aatcgaaatc tttcttttca gcgcttcatc cgaaaggcct gctcccctgc ccaccatatt 75541 ctcagctttt gaatctgtca aaaccgttga aaccgcgctg ctggtcgtgg tattgccaat 75601 acccatttct cccgtgccta aaagatttac tcctttcctg ccaagttcct ccacaatgga 75661 aattccgacc tctatggcct ctattgcctc tttgcgcgtc attgcgggcc cttttgcaat 75721 attccaggta ccttttctta ctttgcgctt tacaattcct tcacagtcca tgtcatcatc 75781 cactccgata tcaaccacta caatatcgga acctgtatgc tttgcaaaag catttatggc 75841 tgttataccc ttcagaaaat tcctggtcac tttggaagta acatctttcg ggcaggaact 75901 tatcccctct tccacaactc cgttgtccgc acacattata ataaccgctt ttttatcaac 75961 acacggaaaa acttctccgg ttatacctgc aagcttttta atgatatctt ccagccttcc 76021 caggctcccc aacggcttcg aaaggctgtc gagcctcctt tgaaccatgt ccatgggttc 76081 tttatacagc tctcctatgg atttcagtgt ttgaaaaagc ataaacaaat ctccttccat 76141 aaggttcttg caagcggtct gaatctttac acgcctgcaa gcaaaattat atttcaatat 76201 ttccggcaaa gcaagtaaac agatatacag gcatataaaa caaaaaacac cttggaattt 76261 cttcaaggtg ttttttgttt ttcgcatatg attttttaag ctttttttac actaatgtac 76321 cccaaaggaa tcctcttttc caccatccag gggcattaaa tccacgtgga gaatctcatc 76381 actgactggt tttctttgaa cttcatggat ttttgccttt attctttttc cgttcaaatt 76441 cacattcacc aatacatcac tgccgttttt gtcaacaatc ggtcttatct catcttctat 76501 caagcttatt ggaatacttt tatcgccttg ataaaggact ccgggaattt tcccttctct 76561 tttaaccttt cgtgaggccg atgtcccaag tgccgttctg ttttcaatat tgagctcaaa 76621 ctcctccata aaaccctctc ctttgttaat attgcggctg tcagtaagaa cagctttatt 76681 aacaaagtat ttccaacaaa atcaccgtta attcatgaat catattataa ccgctacatt 76741 tcttccaact catatgtacc ggtttcttta taatacaagt ataaaagtgc ctttataatg 76801 tcgttgcaat tctcgtatgt tactgtatgg atgtcgcctt tgtccacctg tatcaaaagt 76861 gtcatcttgt gtttgtcgct gttgtcaatt accgtactta tcagatcaat tgcctgaagc 76921 ggtttgtagt atacataaat ccaatgtcca acatcattat ccatatccaa cttcttctga 76981 taataacttt ccaaaaagtt cttgatttct ccgggtttct ttgacaatag atttacagta 77041 acatacattt aaaaaattcc cctcactttt tacatttttt aattaagcaa attgtactaa 77101 tatcaagcaa tttgcataag cttaatattt atattgattt caacaaaatc tataaaaaaa 77161 cctttatgta attttttcat tatcaactgc cgggctgtaa tcagtatttt taattattat 77221 tattgaaata atataaataa cagctttacc tgataaattt ataaagtaaa cataaggtta 77281 tttataaatt taaaaacttc ttaaaaaaac tttaaatcta caaagaatgg aggaaaagcg 77341 ttaaactgcg tttaatgctt gatgcctatg aaaaaagtgc taaataccgc caaaaaatac 77401 tggatggttt ctttaatcat atcattaatc tttagcggct gcagcagcaa agaaaataac 77461 aagaaaaata atgaaaatcc gcaagcaaaa cagcagcagc tgggttccca aacccaggaa 77521 gatgagattc cccagcagct ggaaagtctg gaaaacaata ttgaaaaaat aattttgact 77581 ttggacgggc cggcaataga attgaaaaaa gagaaacagc aaaatcaagg aaaaaaaggc 77641 agcgaaaagg aacaaggaga acaaggcacc caagacagaa aacagagcga agagaaaaac 77701 gataaatcca aagaaaatga agaaagtgaa aaggaagagt ccaaaaataa aaaagatgaa //