LOCUS NZ_ACVX01000030 50361 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00035, whole genome shotgun sequence. ACCESSION NZ_ACVX01000030 NZ_ACVX00000000 VERSION NZ_ACVX01000030.1 GI:256005425 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 50361) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 50361) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000030. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..50361 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene complement(42..215) /locus_tag="ClothDRAFT_2250" CDS complement(42..215) /locus_tag="ClothDRAFT_2250" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430389.1" /db_xref="GI:256005426" /translation="MTQGVSSPLKKLVEGRKVKRDARPRDVKNYSCSVVTERSKKAEI GEKIVAEKLAGKI" gene complement(268..528) /locus_tag="ClothDRAFT_2251" CDS complement(268..528) /locus_tag="ClothDRAFT_2251" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430390.1" /db_xref="GI:256005427" /translation="MSKKNNNLSDVEFSAIQYSLLVNGVCIPPQDELRVIYAHITTSF VFPDLLVVIKSNEGSLFVYEHLIIQNIVSIFDTELYIATKEE" gene 900..1856 /locus_tag="ClothDRAFT_2252" CDS 900..1856 /locus_tag="ClothDRAFT_2252" /inference="protein motif:TFAM:TIGR00005" /note="TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; KEGG: pca:Pcar_2950 suppressor of FtsH mutation" /codon_start=1 /transl_table=11 /product="pseudouridine synthase, RluA family" /protein_id="ZP_05430391.1" /db_xref="GI:256005428" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR006225" /translation="MNLKYTVDKETSGKTVKHILKKQLKLSERLIKKLKRQGKILCNN RPVYVNAVVCENDIIEVDLDFDDSGIFIQPEDIPIDIIYEDEFLIALNKQPGIVVHPT CSHPGGTLANAVAFHLQKKGIVKKIRPVIRLDRDTSGIIIFAKNPYCQEFLIRQMNDK TFIKEYIGIVHKVLENDNGTIDLPIARKPGSIMLRHISPDGDPAVTHYTVLERLNGAT LVKFRLETGRTHQIRVHCQAIGHPLLGDTLYPFEDTPYSLSGNNPHITQANTPSITSG IITRQALHSQRAVFLHPFTKKILEITAPIPEDMKSALEILRK" misc_feature 906..1820 /locus_tag="ClothDRAFT_2252" /note="Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564" /db_xref="CDD:30910" misc_feature 1161..1769 /locus_tag="ClothDRAFT_2252" /note="PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF...; Region: PseudoU_synth_RluCD_like; cd02869" /db_xref="CDD:30029" misc_feature order(1290..1301,1596..1598) /locus_tag="ClothDRAFT_2252" /note="active site" /db_xref="CDD:30029" gene 2064..2636 /locus_tag="ClothDRAFT_2253" CDS 2064..2636 /locus_tag="ClothDRAFT_2253" /inference="protein motif:PFAM:PF00376" /note="PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: sil:SPO2496 MerR family transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, MerR family" /protein_id="ZP_05430392.1" /db_xref="GI:256005429" /db_xref="InterPro:IPR000551" /translation="MEVIKDRYSITELSGYLNVTDHTLRYYEREFNLYVPKDKRGRRY YTPELANIMYKIKTMRDEGLEIKAIKKILQSENVITEPPPVVTEDISVPVAKHNYGEN LVDIKTFFQEFEKQLTNSVALEVELAKEHMTNELNKTKLELGACLENNIRRLESKLDK HFENVDRSISMWREKNKDSLLKRLKKKVFK" misc_feature 2085..2285 /locus_tag="ClothDRAFT_2253" /note="Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg1; cd04764" /db_xref="CDD:133392" misc_feature order(2088..2096,2136..2138,2184..2192) /locus_tag="ClothDRAFT_2253" /note="DNA binding residues" /db_xref="CDD:133392" gene complement(2683..3093) /locus_tag="ClothDRAFT_2254" CDS complement(2683..3093) /locus_tag="ClothDRAFT_2254" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dvl:Dvul_0539 response regulator receiver protein" /codon_start=1 /transl_table=11 /product="response regulator receiver protein" /protein_id="ZP_05430393.1" /db_xref="GI:256005430" /db_xref="InterPro:IPR001789" /translation="MRILIAEDDYASRKFLYKFLSAYGECDITIDGIEAVDAFMLALD EGKPYDLVCLDIMMPKLDGTRALKAIRDVEKQRGIEGDSRVKVIMTTALNDTTNVYNA FDSGCEAYAAKPIDTKKFTEVLKRIGLISECETK" misc_feature complement(2713..3084) /locus_tag="ClothDRAFT_2254" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(2752..2757,2764..2766,2821..2823, 2905..2907,2929..2931,3070..3075)) /locus_tag="ClothDRAFT_2254" /note="active site" /db_xref="CDD:29071" misc_feature complement(2929..2931) /locus_tag="ClothDRAFT_2254" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(2905..2913,2917..2922)) /locus_tag="ClothDRAFT_2254" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(2749..2757) /locus_tag="ClothDRAFT_2254" /note="dimerization interface; other site" /db_xref="CDD:29071" gene complement(3142..5850) /locus_tag="ClothDRAFT_2255" CDS complement(3142..5850) /locus_tag="ClothDRAFT_2255" /inference="protein motif:TFAM:TIGR00229" /note="KEGG: glo:Glov_3522 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; ATP-binding region ATPase domain protein" /codon_start=1 /transl_table=11 /product="multi-sensor hybrid histidine kinase" /protein_id="ZP_05430394.1" /db_xref="GI:256005431" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR000700" /db_xref="InterPro:IPR001610" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013655" /db_xref="InterPro:IPR013656" /db_xref="InterPro:IPR013767" /translation="MDCRVKNEVRDDLNVNLEVMVAGNDEEFAASLKNALLDVGCKHS VKSAATFNEFKNYLRKNNFHIVFFDCSSDISFADVMESFENLKKEMPVVAVLEEDGSR HGFEMIKLGACEYLEKKDSSRLRSIIFKRCRELERERERIRFEKRLKEENERLLTTLE SIGDGVIVTDKAGCVIMMNKAAQELTGYLSCNSIGKPLSEVFVIINGVNREPEPDPYE RVLSERKTVGLRKNTMLVSKDGTLRYVSASTAPIKSSDREIMGVVVVFRDITRIRKAE EKLQKLSQAVEQSPGIIVMADTRGNIEYVNPRFTEVTGYSFDEVKGKSLFFMELEENG EEKCKDMIQAVFSGKEWRSEIRHKSKNNVVFWEYAYYSPIINSEGVVTNYLKVSEDIT ERKLMSENLFKAKEAAEAANRAKSEFLANMSHEIRTPLNGIIGMTNLTLQTELTDEQR ENLNIVNSCAELLLRVINDILDYSKIEAGKMTLENVKFDFFNLLEKTYKAHIVQANEK GLRLSYTVQKGIPRILVGDPGRLQQVLNNLISNAVKFTDIGEVRIDVDIIEKRDDSVK LKFTVSDTGIGIDGDKMNMLFKSFSQVDSSITRKYGGTGLGLAISKQLVEMMGGEIWV ESQKGKGSTFYFTAGFKRKAKSSVKAECTSNADERVLGRKLNILLAEDDKVNQQVIAG MLKKEQCSLTIAENGFEAIKLFEENEFDLILMDVQMPEMDGIEATKRIRKMEEGTFRH IPIIAVTAFAFENDREKILEAGMDDYISKPFSFDDIYAAINRVLYKDEQSSDDMQKEK EDEKGSLDPDEKVNETLSESGTVNETGPDYSLKDIMERLDLSILNGNFTAIDKSALAV KEFAQNRGFDKVKNLAFKIQLSARKNQLEDVKKLYEVLKQEISKFN" misc_feature complement(<5467..5796) /locus_tag="ClothDRAFT_2255" /note="Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204" /db_xref="CDD:32386" misc_feature complement(5014..5370) /locus_tag="ClothDRAFT_2255" /note="PAS domain S-box; Region: sensory_box; TIGR00229" /db_xref="CDD:161776" misc_feature complement(5044..5367) /locus_tag="ClothDRAFT_2255" /note="PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130" /db_xref="CDD:29035" misc_feature complement(order(5131..5133,5146..5148,5221..5226, 5245..5250,5287..5289,5305..5307,5317..5319)) /locus_tag="ClothDRAFT_2255" /note="putative active site; other site" /db_xref="CDD:29035" misc_feature complement(order(5104..5106,5110..5112,5191..5196, 5203..5205,5245..5247,5257..5259)) /locus_tag="ClothDRAFT_2255" /note="heme pocket; other site" /db_xref="CDD:29035" misc_feature complement(3940..5025) /locus_tag="ClothDRAFT_2255" /note="phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966" /db_xref="CDD:163090" misc_feature complement(4678..4986) /locus_tag="ClothDRAFT_2255" /note="PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130" /db_xref="CDD:29035" misc_feature complement(order(4765..4767,4780..4782,4858..4869, 4906..4908,4924..4926,4936..4938)) /locus_tag="ClothDRAFT_2255" /note="putative active site; other site" /db_xref="CDD:29035" misc_feature complement(order(4738..4740,4744..4746,4828..4833, 4840..4842,4864..4866,4876..4878)) /locus_tag="ClothDRAFT_2255" /note="heme pocket; other site" /db_xref="CDD:29035" misc_feature complement(4426..4599) /locus_tag="ClothDRAFT_2255" /note="Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-...; Region: HisKA; cd00082" /db_xref="CDD:119399" misc_feature complement(order(4441..4443,4453..4455,4462..4464, 4474..4476,4483..4485,4495..4497,4543..4545,4552..4554, 4564..4566,4573..4575,4585..4587,4597..4599)) /locus_tag="ClothDRAFT_2255" /note="dimer interface; other site" /db_xref="CDD:119399" misc_feature complement(4579..4581) /locus_tag="ClothDRAFT_2255" /note="phosphorylation site" /db_xref="CDD:119399" misc_feature complement(3940..4260) /locus_tag="ClothDRAFT_2255" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature complement(order(3949..3951,3955..3960,3973..3975, 3979..3981,4027..4038,4117..4122,4126..4128,4132..4134, 4138..4140,4219..4221,4228..4230,4240..4242)) /locus_tag="ClothDRAFT_2255" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature complement(4228..4230) /locus_tag="ClothDRAFT_2255" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature complement(order(4030..4032,4036..4038,4120..4122, 4126..4128)) /locus_tag="ClothDRAFT_2255" /note="G-X-G motif; other site" /db_xref="CDD:28956" misc_feature complement(3499..3849) /locus_tag="ClothDRAFT_2255" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(3541..3546,3553..3555,3610..3612, 3682..3684,3706..3708,3835..3840)) /locus_tag="ClothDRAFT_2255" /note="active site" /db_xref="CDD:29071" misc_feature complement(3706..3708) /locus_tag="ClothDRAFT_2255" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(3682..3690,3694..3699)) /locus_tag="ClothDRAFT_2255" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(3538..3546) /locus_tag="ClothDRAFT_2255" /note="dimerization interface; other site" /db_xref="CDD:29071" gene complement(5866..6900) /locus_tag="ClothDRAFT_2256" CDS complement(5866..6900) /locus_tag="ClothDRAFT_2256" /EC_number="3.1.1.61" /inference="protein motif:PRIAM:3.1.1.61" /note="KEGG: pca:Pcar_1200 chemotactic response regulator/methylesterase; PFAM: CheB methylesterase; response regulator receiver; SMART: response regulator receiver" /codon_start=1 /transl_table=11 /product="response regulator receiver modulated CheB methylesterase" /protein_id="ZP_05430395.1" /db_xref="GI:256005432" /db_xref="InterPro:IPR000673" /db_xref="InterPro:IPR001789" /translation="MRTSNMKRKIKVLVVDDSLLFREKISKGIAQDASIEVVATASDP YEARDKIIEFKPDVMTLDVEMPRMNGIEFLKRLMPQYPIPVVVVSAVSHNVFDALNAG AVDFVTKPDLSTQRGFDFLINELIIKIKIASMAKVGHWKKEYADLKTIGSMNREASSK IIAIGASTGGTEAIYNLLRAFPRDIPGTVIVQHMPPVFTRMYAERLNNSCLMEVKEAQ TGDRVCQGRVLIAPGDHHMTIKKSGSGYIVECTKGEKVSGHCPSVDVLFNSVAEVAGK NAIGIILTGMGKDGAKGLLAMRQKGARTLGQDEKSCVVYGMPKVAFEIGAVEKQVSLE AIPQLVYSML" misc_feature complement(5887..6879) /locus_tag="ClothDRAFT_2256" /note="chemotaxis-specific methylesterase; Provisional; Region: PRK00742" /db_xref="CDD:179106" misc_feature complement(6511..6864) /locus_tag="ClothDRAFT_2256" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(6571..6576,6583..6585,6640..6642, 6691..6693,6715..6717,6850..6855)) /locus_tag="ClothDRAFT_2256" /note="active site" /db_xref="CDD:29071" misc_feature complement(6715..6717) /locus_tag="ClothDRAFT_2256" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(6691..6699,6703..6708)) /locus_tag="ClothDRAFT_2256" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(order(6541..6543,6571..6576)) /locus_tag="ClothDRAFT_2256" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature complement(5887..6420) /locus_tag="ClothDRAFT_2256" /note="CheB methylesterase; Region: CheB_methylest; pfam01339" /db_xref="CDD:144802" gene complement(6917..7735) /locus_tag="ClothDRAFT_2257" CDS complement(6917..7735) /locus_tag="ClothDRAFT_2257" /EC_number="2.1.1.80" /inference="protein motif:PRIAM:2.1.1.80" /note="KEGG: pca:Pcar_1199 methylase of chemotaxis methyl-accepting protein, CheR-like; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type" /codon_start=1 /transl_table=11 /product="MCP methyltransferase, CheR-type" /protein_id="ZP_05430396.1" /db_xref="GI:256005433" /db_xref="InterPro:IPR000780" /translation="MLHISKKEFDQLAAYVKSNYGINLTEKKKTLVVGRLQNILQQMN FTSFSDYYDYVMSDTTGEAVTTLINKITTNHTFFMREPDHFDFFASTVLPYLSATIKR PLDLRIWSAGCSSGEEPYTLAMIIADFFGPQKPLWDTRILATDISVNVIQKAKAGIYS NERIEGVPEAWKRKYFRKVDENNWAVVDSIRNEVIFRIFNLMNTVFPFKRKFHVIFCR NVMIYFDQQTKMELVNRFYEYTEPGGYLFIGHSESLNRDETKYKYVMPAVYRKE" misc_feature complement(7562..7723) /locus_tag="ClothDRAFT_2257" /note="CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705" /db_xref="CDD:112515" misc_feature complement(6923..7720) /locus_tag="ClothDRAFT_2257" /note="Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138" /db_xref="CDD:128443" misc_feature complement(6950..7516) /locus_tag="ClothDRAFT_2257" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene complement(7761..8252) /locus_tag="ClothDRAFT_2258" CDS complement(7761..8252) /locus_tag="ClothDRAFT_2258" /inference="protein motif:PFAM:PF01584" /note="PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: dal:Dalk_3928 CheW protein" /codon_start=1 /transl_table=11 /product="CheW protein" /protein_id="ZP_05430397.1" /db_xref="GI:256005434" /db_xref="InterPro:IPR002545" /translation="MSEALENVLEYEEDTQKGKYLTFIIGKEVYGIEIKYVTEIIGMQ QITEVPELPEYIKGIINLRGKIIPVLDVRLRFKKEPMEYNDRTCIIVVDIKDVSVGLI VDSVAEVVSIPEENIVPPPEANTGFNNRYIKQIGKVGDEVKLLLDCNKLLNDEDCENL LNI" misc_feature complement(7830..8198) /locus_tag="ClothDRAFT_2258" /note="CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732" /db_xref="CDD:29682" misc_feature complement(order(7965..7967,7971..7973,8055..8072)) /locus_tag="ClothDRAFT_2258" /note="putative CheA interaction surface; other site" /db_xref="CDD:29682" gene complement(8269..10416) /locus_tag="ClothDRAFT_2259" CDS complement(8269..10416) /locus_tag="ClothDRAFT_2259" /inference="protein motif:PFAM:PF02518" /note="PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: dal:Dalk_3929 CheA signal transduction histidine kinase" /codon_start=1 /transl_table=11 /product="CheA signal transduction histidine kinase" /protein_id="ZP_05430398.1" /db_xref="GI:256005435" /db_xref="InterPro:IPR002545" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004105" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR008207" /translation="MTDNVSREPMLDMFIFETLQLLDQLEQSLINSEKESGFESSIDE IFRIMHTIKGSAAMMLFDDISKLAHSIEDLFFYLREEKPENVNSTEIIDIVLNGVDFI KNETVKLENGQEPDGDASDLIKEIRDYLGNLKSINNAGSDSPDSESSHTLEVEKDQKY YISSNKAASTPKSHKYEAVLKFEEQCGMENIRAFSVIHDLKEIADVNYFYPEDVIDGG GKSENSEIIQKDGFRVVFSTDLGLDEVKERLSHTILLKSLDVYVINEDLEDIMGDMPD TRETELKEQKLKMDGKANVLNDSSQASEQNEHSSGRQLSNEKKTGPSADNTASSSKQS VISVNIAKLDKLMDLVGEIVISEAMVTQNPDLEGLQLDNFHKAARQLNKLTNELQDVV MSIRMVPLSMTFQKMNRIVRDMGKKLNKSIELEIIGEETEVDKNIIERISDPLIHLIR NAVDHGLEDPDERVAKGKPPAGKITLEAKNAGGDVWIFVKDDGRGLDREKILKKAREA GLIHKPENELTDKEIYSFIFTPGFSTKENVTEFSGRGVGMDIVSNNISMVGGTIFVDS VPDNGTTISIKLPLTLAIINGMSIKVGKSRYTIPTISIKESFKVKNEAVITDSEGNEM IMVRGEVYPVLRLHKFYKINTEVTNINDGIIVMVESDSRVICIFADELLGEQQVVVKA LPKYIKKVKGIGGCTLLGDGSISLILDVAGLVS" misc_feature complement(8275..10413) /locus_tag="ClothDRAFT_2259" /note="Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643" /db_xref="CDD:30988" misc_feature complement(10102..10395) /locus_tag="ClothDRAFT_2259" /note="Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088" /db_xref="CDD:28972" misc_feature complement(order(10201..10203,10210..10212,10255..10260, 10267..10269)) /locus_tag="ClothDRAFT_2259" /note="putative binding surface; other site" /db_xref="CDD:28972" misc_feature complement(10267..10269) /locus_tag="ClothDRAFT_2259" /note="active site" /db_xref="CDD:28972" misc_feature complement(9637..9897) /locus_tag="ClothDRAFT_2259" /note="P2 response regulator binding domain; Region: P2; pfam07194" /db_xref="CDD:148665" misc_feature complement(9232..9420) /locus_tag="ClothDRAFT_2259" /note="Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895" /db_xref="CDD:145841" misc_feature complement(8683..9096) /locus_tag="ClothDRAFT_2259" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature complement(order(8695..8697,8701..8706,8719..8721, 8725..8727,8773..8784,8929..8934,8938..8940,8944..8946, 8950..8952,9055..9057,9064..9066,9076..9078)) /locus_tag="ClothDRAFT_2259" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature complement(9064..9066) /locus_tag="ClothDRAFT_2259" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature complement(order(8776..8778,8782..8784,8932..8934, 8938..8940)) /locus_tag="ClothDRAFT_2259" /note="G-X-G motif; other site" /db_xref="CDD:28956" misc_feature complement(8278..8673) /locus_tag="ClothDRAFT_2259" /note="CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731" /db_xref="CDD:29681" gene complement(10458..10811) /locus_tag="ClothDRAFT_2260" CDS complement(10458..10811) /locus_tag="ClothDRAFT_2260" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: ank:AnaeK_4453 response regulator receiver protein" /codon_start=1 /transl_table=11 /product="response regulator receiver protein" /protein_id="ZP_05430399.1" /db_xref="GI:256005436" /db_xref="InterPro:IPR001789" /translation="MKRILVVDDAGFMRASLKMMLERHGHQVVGEAENGLVAVTKYKE IRPDIVTMDITMPVCDGIKAVKMIKEFDPDAKVIMISSMGQECFVRDAILAGAKGFIV KPFKEDYVIQAIEKL" misc_feature complement(10461..10799) /locus_tag="ClothDRAFT_2260" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(10500..10505,10512..10514,10569..10571, 10629..10631,10653..10655,10785..10790)) /locus_tag="ClothDRAFT_2260" /note="active site" /db_xref="CDD:29071" misc_feature complement(10653..10655) /locus_tag="ClothDRAFT_2260" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(10629..10637,10641..10646)) /locus_tag="ClothDRAFT_2260" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(10497..10505) /locus_tag="ClothDRAFT_2260" /note="dimerization interface; other site" /db_xref="CDD:29071" gene complement(11284..12093) /locus_tag="ClothDRAFT_2261" CDS complement(11284..12093) /locus_tag="ClothDRAFT_2261" /inference="protein motif:TFAM:TIGR02875" /note="KEGG: mxa:MXAN_6959 protein-glutamate methylesterase; TIGRFAM: sporulation transcription factor Spo0A; PFAM: Sporulation initiation factor Spo0A ; response regulator receiver; SMART: response regulator receiver" /codon_start=1 /transl_table=11 /product="sporulation transcriptional activator Spo0A" /protein_id="ZP_05430400.1" /db_xref="GI:256005437" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR012052" /db_xref="InterPro:IPR014879" /translation="MTSNKIRVVIADDNREFGDILYEYLNNQEDIEVVGVARDGIEAY ELIVEKLPDIAILDIIMPHLDGLGVLEKIGATAISKRPLFIILSAVGQDKITQRALAL GAEYYVVKPFDMEVLISRIRQLKNVNQPNVIRQDGLSGEVKSSYHPPQPKNLEAEVTN IMHEIGVPAHIKGYQYLRDAIIMVVKDLDVINSITKQLYPTIAKEYNTTPSRVERAIR HAIEVAWSRGQIDTIDSLFGYTINVGKGKPTNSEFIAMVADKLRLEMKMAT" misc_feature complement(11296..12081) /locus_tag="ClothDRAFT_2261" /note="sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875" /db_xref="CDD:131922" misc_feature complement(11722..12069) /locus_tag="ClothDRAFT_2261" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(11761..11766,11773..11775,11830..11832, 11896..11898,11920..11922,12055..12060)) /locus_tag="ClothDRAFT_2261" /note="active site" /db_xref="CDD:29071" misc_feature complement(11920..11922) /locus_tag="ClothDRAFT_2261" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(11896..11904,11908..11913)) /locus_tag="ClothDRAFT_2261" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(11758..11766) /locus_tag="ClothDRAFT_2261" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature complement(11308..11625) /locus_tag="ClothDRAFT_2261" /note="Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769" /db_xref="CDD:149736" gene complement(12457..13734) /locus_tag="ClothDRAFT_2262" CDS complement(12457..13734) /locus_tag="ClothDRAFT_2262" /EC_number="3.4.21.116" /inference="protein motif:TFAM:TIGR02860" /note="KEGG: spl:Spea_1215 peptidase S41; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB" /codon_start=1 /transl_table=11 /product="stage IV sporulation protein B" /protein_id="ZP_05430401.1" /db_xref="GI:256005438" /db_xref="InterPro:IPR008763" /db_xref="InterPro:IPR014219" /translation="MSIAYIRLISVFPNQLTLFENQEYIYKFKSPLLVNLVNFKSDNN DILIFDSEDIKINNDDYKDTKNKVMFKASKLGRTSLSLKLLGLIPLKTMYVDVVPYKE VVACGNTVGVKIKVDGILVIGLSDVETPDGRRLIPARDSGLKPGDLIVEVNNNKVDTA YDLMNEVENSMGENIWVKYKRGNSYNNTKVTPVKSAEDNKYRVGMWVRDSTAGIGTLT FYDPVTKGFGALGHGITDIDTGAIMPVQRGELVESNILTVKKGTKGNPGELKGVLIED SGVLGTIVKNSHYGIYGTLNDAALDKFPNVKYPIALRNDIKVGPATILANIDGKKVEE YSIEIEKVSRKSANGLKGMVIRVTDDRLLEATGGIVQGMSGSPILQDGKLVGAVTHVL VNDPARGYGILIEWMIKNMADANLQNVEMANAS" misc_feature complement(12508..13731) /locus_tag="ClothDRAFT_2262" /note="stage IV sporulation protein B; Region: spore_IV_B; TIGR02860" /db_xref="CDD:163044" misc_feature complement(13159..>13326) /locus_tag="ClothDRAFT_2262" /note="PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most...; Region: PDZ_metalloprotease; cd00989" /db_xref="CDD:29046" misc_feature complement(12508..13158) /locus_tag="ClothDRAFT_2262" /note="SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580" /db_xref="CDD:114310" gene complement(14038..15750) /locus_tag="ClothDRAFT_2263" CDS complement(14038..15750) /locus_tag="ClothDRAFT_2263" /inference="protein motif:TFAM:TIGR00634" /note="TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: gur:Gura_1707 DNA repair protein RecN" /codon_start=1 /transl_table=11 /product="DNA repair protein RecN" /protein_id="ZP_05430402.1" /db_xref="GI:256005439" /db_xref="InterPro:IPR003395" /db_xref="InterPro:IPR004604" /translation="MLQRLEIQNVAIIDKVEIELGDGLNVLTGETGAGKSIIIDSINA ILGQRLYKDLIRTGRDKAIVEAVFQVDKKRVEDLLEDFGIDWEEDGTLVVSREFTTSG KNTCRINGRIATVSMLKQLGERLIDVHGQHDNQSLLRTESHIDLLDSFASSRLQSLKD EYLKHLETYRKIKSRLKELTGDKNERERKIDILKYQIDEIKKAKLKTGEEEELSKQRE LLVNSEKITNTLSNAYELLGSGGKFGESALDMINKAASDFGGIEEFDAKYDELKKRIE AVAIELDDIVSEIRNLRDNMEYDPDLLMQIESRLDVLYRLKKKYGDSVEEILEYKDKI EKELDEILNNEEIVNKLNEELLEEDGKLYRLAKEMNNERVKASKLLEEKIGEELKDLE MKNTSFKVRIDFDDSTENGERKYNNNGLDRVEFMISTNAGEPLKPLAKIASGGEMSRV MLAIKTILAKVDKIPTMIFDEIDIGISGVAAQKVGEKLCYISKNHQVISVTHLAQIAC MADNNYYIDKVTENGNTRTVVKKLDERGKRDEIARILGGASITDITLKHAEEMLDKAK EFKK" misc_feature complement(14050..15750) /locus_tag="ClothDRAFT_2263" /note="ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497" /db_xref="CDD:30843" misc_feature complement(<15304..15747) /locus_tag="ClothDRAFT_2263" /note="RecN ATPase involved in DNA repair; ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides...; Region: ABC_RecN; cd03241" /db_xref="CDD:73000" misc_feature complement(15643..15666) /locus_tag="ClothDRAFT_2263" /note="Walker A/P-loop; other site" /db_xref="CDD:73000" misc_feature complement(order(15331..15333,15640..15648,15652..15657)) /locus_tag="ClothDRAFT_2263" /note="ATP binding site; other site" /db_xref="CDD:73000" misc_feature complement(15331..15342) /locus_tag="ClothDRAFT_2263" /note="Q-loop/lid; other site" /db_xref="CDD:73000" misc_feature complement(14110..>14499) /locus_tag="ClothDRAFT_2263" /note="RecN ATPase involved in DNA repair; ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides...; Region: ABC_RecN; cd03241" /db_xref="CDD:73000" misc_feature complement(14398..14427) /locus_tag="ClothDRAFT_2263" /note="ABC transporter signature motif; other site" /db_xref="CDD:73000" misc_feature complement(14338..14355) /locus_tag="ClothDRAFT_2263" /note="Walker B; other site" /db_xref="CDD:73000" misc_feature complement(14320..14331) /locus_tag="ClothDRAFT_2263" /note="D-loop; other site" /db_xref="CDD:73000" misc_feature complement(14239..14259) /locus_tag="ClothDRAFT_2263" /note="H-loop/switch region; other site" /db_xref="CDD:73000" gene complement(15806..16267) /locus_tag="ClothDRAFT_2264" CDS complement(15806..16267) /locus_tag="ClothDRAFT_2264" /inference="protein motif:TFAM:TIGR01529" /note="TIGRFAM: arginine repressor; PFAM: arginine repressor; KEGG: afw:Anae109_0631 arginine repressor, ArgR" /codon_start=1 /transl_table=11 /product="arginine repressor, ArgR" /protein_id="ZP_05430403.1" /db_xref="GI:256005440" /db_xref="InterPro:IPR001669" /translation="MKHARQAKILEIIDKEVIETQEEIADRLKKAGMEVTQATISRDI KELRLIKVMTEDGRYKYAPFNSTDNTVFNRLMTVFSKSYVSSDYANNIVVVKTLPGMA PAAASAIDSMNYPEIVGSIAGDDTVLIVCRSEKIAKEFVEKLSKLAKSDDK" misc_feature complement(15821..16267) /locus_tag="ClothDRAFT_2264" /note="arginine repressor; Provisional; Region: argR; PRK00441" /db_xref="CDD:179027" misc_feature complement(16082..16264) /locus_tag="ClothDRAFT_2264" /note="Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316" /db_xref="CDD:110329" misc_feature complement(15827..16036) /locus_tag="ClothDRAFT_2264" /note="Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863" /db_xref="CDD:145816" gene complement(16269..17138) /locus_tag="ClothDRAFT_2265" CDS complement(16269..17138) /locus_tag="ClothDRAFT_2265" /inference="protein motif:PFAM:PF01513" /note="PFAM: ATP-NAD/AcoX kinase; KEGG: sat:SYN_02863 ATP-NAD kinase" /codon_start=1 /transl_table=11 /product="ATP-NAD/AcoX kinase" /protein_id="ZP_05430404.1" /db_xref="GI:256005441" /db_xref="InterPro:IPR002504" /translation="MLKIGIIPNEDKDEELKYTRILVDSIKKCGGTAIVCDDIALKLG DKESNINEDNIVDMSDVMVCLGGDGTFLKAARMTVVKGKPLLGVNLGKLGFLADVDKN DIENAVKRLVEDKFTVDERMMLDTVIVRDGKIIAEDIVLNDVVISRGAISRILHLKTY INDAFMDLYPGDGLIISTPTGSTAYSLSAGGPLVEPDVDLIICTPICPHLLYSRSFIT TADRVIKVVVAESSSHEAMVTVDGQNGYEVRGGDVIITKKSRIRMPMVRLNGKNFFDV LRGKIYDRGESMK" misc_feature complement(16299..17135) /locus_tag="ClothDRAFT_2265" /note="Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl01255" /db_xref="CDD:186404" gene 17491..22971 /locus_tag="ClothDRAFT_2266" CDS 17491..22971 /locus_tag="ClothDRAFT_2266" /inference="protein motif:TFAM:TIGR00254" /note="KEGG: gur:Gura_2258 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; tyrosine protein kinase; TPR repeat-containing protein; ATPase; Tetratricopeptide TPR_2 repeat protein; SMART: GGDEF domain containing protein; serine/threonine protein kinase; Tetratricopeptide domain protein" /codon_start=1 /transl_table=11 /product="diguanylate cyclase and serine/threonine protein kinase with TPR repeats" /protein_id="ZP_05430405.1" /db_xref="GI:256005442" /db_xref="InterPro:IPR000160" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR001245" /db_xref="InterPro:IPR001440" /db_xref="InterPro:IPR002290" /db_xref="InterPro:IPR011579" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR013105" /translation="MNIINNRYKVITTIKEDLSNTLYLVSDMINDNKKMAFKIINPEL ISPKNLEQLKKEFVTLSSLSHPNLMQIYGFGTINSIDGSLTSSKQFYCTYEYIKGKNI ISAVSGTSFEKKIDIILQICNALYYLHRRGFFLKNLDHKSVVVTETDGNLCVKLIGMP GNEEMEKVVFRLKKISNQFKFPEDLKSSNNNSNLADLYSLGVLIFYILTGKNPNRCNF LNIWEQCKNNPSVLKSVPDNIDKKRLLGIISKLTLTNPENHYKSAYSVIKDIEKVCGI KETRFQKKWFEKIITKTKLIGREENINRLNSWINDISNNNCSQKITCITGEAGIGKTR LLGELMFSLSLEKTRVLHGVSSENAENTYEPIKQILEQLIPYAPAEILESFKSELVKI LPDEKSLKGAVPSPALPDEKEKLRLKVRVGNFIANVLEKELSVLIFDNAQWLDEASLE LIDYLAGSKKIPLCIILSYRKESMNKNKSGQKYIEKWLSSSIANEITLSRFDFEETCE FIKNVLAITTSPAAFCTEMFRYTEGNPGFIIDAITALFKEGKLYIDDSGQWSTDFDED ADYSRLYIPPSMHEAVWKHINTLDKISYETLETISAFNMPVSLEIIESILEASHNEIK DILAELISHQIIEQRLADWGYTYDYHSKKIKNEIYKKIEPSRKKALHKKCAKILEEMY KDDNRINKDELIYHYIKTGEKQKALNIIIESADRMLKLHINAQTMVYLKRGRQIAKEI SSVKDTIKILLMMGELYRKKGENRKAFECYNEALKYARELNDKATIAKVKEMIGALYT RKNDFDRALLFLNDSLSLSKEIGYVEGYLEAVRRICWVYIFKGKNKEAIDMINNVLSE YSNEKYSLYHASLYNVLGTHYLEQSNIDEALRCYNKSIELYEKNNEKVEIAYPLNNIA TVFAEFLNDNAKAREYFEKSLQINLANNMVEGISSCYDNLGETYRLEDNYTQALEYYF KCEEQARECELNSLLFTVYKNIMLAYLELCEYQKSYEYLQKVKQEMEKNSDRGHDVQI FYEYAAKYYFEIGCFEEAKNMAQKGINTCKKLSTSESLTLNCIILLSEYYVSNQKDSE LLFEDALTLLKRHKQSSTVKEQRDMIHLLAEALIASGNTEASLSLLEKSLELSATVNT KKLEIEYLILYGASIGGNCGIETINSGLKLNAEYKSLRLKWKGYKTIGDIYYSMKEKS LAGINYIKALDALYHLVQKVPVEFHGCFLYSHNREESRFRLLSLKADELKEQELSIEK HINNKINSGKNIVQHFFEGINHEFVLKGAESAMALDSAQSHASKAIEEKLGMIESLFM KFTPDYLSNLKMILETACDLTSAETGYILRYNDKNELDAFVAYDSNTEANYYSYIIER TNENIEGIFAAQSFDKKAGNIDIFLPGNIKAVICIPIYSHESGDRYSSVKPSKRKRRE SNDYNIKGYIYLSTKNVFNRFSWQTFGMVKLLSKIAALQIENYDLKIISTTDKLTGTY TRKFFENAIETQLKKASREKSQMSIIMIDIDKFKSINDNYGHQKGDEILSKVGNILLK NIRPTDICCRYGGEEFVIILPDTGPSEAEALAERLRSTVEKARLMGQGNSLTISLGIS CYPKHGSIRNELIEKADQALYHAKESGRNRYSLWNTKMKKLSKRMDKLAGIISGNVTH DQRNVLALLEIVRLSNETMLFDDKIYRVLGTIIDTFDAEYGVLIVCQEQNPKTLKVYA RKSTVPGWVEEECYNKKIVDKVLKQKAGAYMVDWDNANVIDLQTGETVLNSILVEPIL RGKEVKGVLYLSRPINRKEYGFNELNFLSALGNVISGILSMP" misc_feature 17551..18111 /locus_tag="ClothDRAFT_2266" /note="Catalytic domain of Protein Kinases; Region: PKc; cd00180" /db_xref="CDD:173623" misc_feature order(17554..17556,17596..17598,17602..17604,17695..17697, 17770..17781,17791..17793,17899..17901,17905..17907, 17911..17916,17920..17922,17965..17967,18013..18024) /locus_tag="ClothDRAFT_2266" /note="active site" /db_xref="CDD:173623" misc_feature order(17554..17556,17596..17598,17602..17604,17695..17697, 17770..17781,17791..17793,17899..17901,17905..17907, 17911..17916,17920..17922) /locus_tag="ClothDRAFT_2266" /note="ATP binding site; other site" /db_xref="CDD:173623" misc_feature 17557..18264 /locus_tag="ClothDRAFT_2266" /note="Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220" /db_xref="CDD:128516" misc_feature order(17791..17793,17899..17901,17905..17907,17911..17913, 17965..17967,18013..18024) /locus_tag="ClothDRAFT_2266" /note="substrate binding site; other site" /db_xref="CDD:173623" misc_feature order(17959..17961,17962..17973,18013..18024) /locus_tag="ClothDRAFT_2266" /note="activation loop (A-loop); other site" /db_xref="CDD:173623" misc_feature 18373..>20343 /locus_tag="ClothDRAFT_2266" /note="Predicted ATPase [General function prediction only]; Region: COG3899" /db_xref="CDD:33687" misc_feature 19732..20067 /locus_tag="ClothDRAFT_2266" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature order(19732..19737,19741..19746,19753..19758,19855..19860, 19870..19875,19882..19887,19981..19986,19993..19998, 20005..20010) /locus_tag="ClothDRAFT_2266" /note="binding surface" /db_xref="CDD:29151" misc_feature order(19750..19752,19786..19788,19798..19800,19807..19809, 19870..19872,19906..19908,19918..19920,19927..19929, 19990..19992,20026..20028,20038..20040,20047..20049) /locus_tag="ClothDRAFT_2266" /note="TPR motif; other site" /db_xref="CDD:29151" misc_feature 20107..20403 /locus_tag="ClothDRAFT_2266" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature order(20110..20112,20146..20148,20158..20160,20167..20169, 20230..20232,20269..20271,20281..20283,20290..20292, 20353..20355,20389..20391,20401..20403) /locus_tag="ClothDRAFT_2266" /note="TPR motif; other site" /db_xref="CDD:29151" misc_feature order(20113..20118,20221..20226,20230..20235,20242..20247, 20344..20349,20356..20361,20368..20373) /locus_tag="ClothDRAFT_2266" /note="binding surface" /db_xref="CDD:29151" misc_feature 20338..20673 /locus_tag="ClothDRAFT_2266" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature order(20338..20340,20344..20349,20356..20361,20464..20469, 20473..20478,20485..20490,20587..20592,20599..20604, 20611..20616) /locus_tag="ClothDRAFT_2266" /note="binding surface" /db_xref="CDD:29151" misc_feature order(20353..20355,20389..20391,20401..20403,20422..20424, 20473..20475,20509..20511,20521..20523,20530..20532, 20596..20598,20632..20634,20644..20646,20653..20655) /locus_tag="ClothDRAFT_2266" /note="TPR motif; other site" /db_xref="CDD:29151" misc_feature 21946..22413 /locus_tag="ClothDRAFT_2266" /note="Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949" /db_xref="CDD:143635" misc_feature order(22057..22059,22186..22188) /locus_tag="ClothDRAFT_2266" /note="metal-binding site" /db_xref="CDD:143635" misc_feature order(22072..22074,22081..22086,22096..22098,22108..22110, 22174..22176,22180..22191) /locus_tag="ClothDRAFT_2266" /note="active site" /db_xref="CDD:143635" misc_feature order(22162..22164,22246..22248) /locus_tag="ClothDRAFT_2266" /note="I-site; other site" /db_xref="CDD:143635" gene complement(23444..24118) /locus_tag="ClothDRAFT_2267" CDS complement(23444..24118) /locus_tag="ClothDRAFT_2267" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430406.1" /db_xref="GI:256005443" /translation="MDKRVNKMVPLIFDLKTVSYVGYFILLAFAAVMIFFLVLMGGAA TKYILLQTTVFVVSVVGVLAWILTPYMEIVQPESKELILSLPIDGFKYGFLRMLRLFA IYTGFVLLLLYFIYSISDGDRLEYGIVDIFLIAGALFFVSGFGMTAFLVSRQLIIGYG IPILWVAISFFYRGGASWLWHTCQWINPKPFESSLKYAVAHWLTGLVLYVVSAFLIEQ RKYLMR" gene complement(24103..24966) /locus_tag="ClothDRAFT_2268" CDS complement(24103..24966) /locus_tag="ClothDRAFT_2268" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ccs:CCNA_03681 ABC transporter ATP-binding protein" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05430407.1" /db_xref="GI:256005444" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /translation="MRLKIEGLSKSYKKKKALDSVNLFISNGIYGLLGPNGAGKTTLM RILAGLIAPDEGRIEFDGEDVLKNMDKFRYKIGYLPQEFGCYKSITVEECLDTIGVLK GIRAPERKKQIEQVLAEVNLSNEAKKKVGALSGGMRRRLGIAQAMLGNPAFIMVDEPT AGLDPEERIRFRGFIRRVAANRVVLLSTHIIEDIKNNCDGLALINNGKVKQFDGFEEL ENMAKGKVWKMVINSNDFYKIEGKYKILSTNTNADNNLEIRVYSEEKPSEDAEAVQPT VEEGYLTWINA" misc_feature complement(24121..24960) /locus_tag="ClothDRAFT_2268" /note="ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131" /db_xref="CDD:31326" misc_feature complement(24325..24960) /locus_tag="ClothDRAFT_2268" /note="ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the...; Region: ABC_drug_resistance_like; cd03264" /db_xref="CDD:73023" misc_feature complement(24844..24867) /locus_tag="ClothDRAFT_2268" /note="Walker A/P-loop; other site" /db_xref="CDD:73023" misc_feature complement(order(24400..24402,24493..24498,24724..24726, 24841..24849,24853..24858)) /locus_tag="ClothDRAFT_2268" /note="ATP binding site; other site" /db_xref="CDD:73023" misc_feature complement(24724..24735) /locus_tag="ClothDRAFT_2268" /note="Q-loop/lid; other site" /db_xref="CDD:73023" misc_feature complement(24541..24570) /locus_tag="ClothDRAFT_2268" /note="ABC transporter signature motif; other site" /db_xref="CDD:73023" misc_feature complement(24493..24510) /locus_tag="ClothDRAFT_2268" /note="Walker B; other site" /db_xref="CDD:73023" misc_feature complement(24475..24486) /locus_tag="ClothDRAFT_2268" /note="D-loop; other site" /db_xref="CDD:73023" misc_feature complement(24394..24414) /locus_tag="ClothDRAFT_2268" /note="H-loop/switch region; other site" /db_xref="CDD:73023" gene complement(25007..27019) /locus_tag="ClothDRAFT_2269" CDS complement(25007..27019) /locus_tag="ClothDRAFT_2269" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430408.1" /db_xref="GI:256005445" /translation="MMVLKKILTLETKLFIRKYYLIIPMFLSFLYMFYGYCIMKDRLD NFSFIRTSGFVMMVLTILSMCFGVINARQDKDAKFEEVLDTLPSAWIRQMAKVFTWSV CSFVYCLVLAIFCTVWVDNGLNELGKYALQVAPYIFVNFYMPMVSTWLIAYSVEKTFN PKLGWPILLLIWYVISPIKNGSSGISLMLNQFVEEPHGNPHLLHYGLEMNIGLLSRKL WFLMFGMSVYIFANLSRLERRNLRNTKAKIAGTAAILLFIGAIPLAAFSTKYHSQGKM RYLDFGIWNDKILEQAKERFEEKYCNGRIKLFHLELGDSKGDLLEYYAKINIDNIKNE PIIFTLYRSLAIKDVKINGTEYNEFVRDRDWIIIQDPPEGEAEIEINVSGRLPYALGE VTDRTLLLRPDFPWYPILGKHKVILPVLTYDYLTNNLSNGKPYDIVLKSHRGNVITNL SCDIGTEFKGQATGPAVIQGDYESGNIGGIHFVAPPSIYYSYKEYISIVPDLLMKYRK EFEDSVGIEADYNLCDKYNKVFLVNLNGSMNGSILVNQNELYLDYSSWLYPASEDGIR RSCEFLRPMFILECFWRTGKYMESSVAPCLFPSLIEIAETGEKKDLEEYYTEWWGEGK EKQIVWENDLNDIYEIERLVKAESKDEVSKIAYEILRKWITVNKSK" gene complement(27091..27489) /locus_tag="ClothDRAFT_2270" CDS complement(27091..27489) /locus_tag="ClothDRAFT_2270" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430409.1" /db_xref="GI:256005446" /translation="MKKIFRKIFPLILACIIVTSVAVDALTFIGVSRVTLSDTQTSNT GSLVALWGTSGQGRLRARSENGLQVTAKAMRVRENWFDEELKTIVTNQTSWTSWTPYF DLKTVNVGYYARIEGSQSAKGQAEFEVYQL" sig_peptide complement(27412..27489) /locus_tag="ClothDRAFT_2270" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.638 at residue 26" gene complement(27956..29632) /locus_tag="ClothDRAFT_2271" CDS complement(27956..29632) /locus_tag="ClothDRAFT_2271" /inference="protein motif:PFAM:PF00754" /note="PFAM: coagulation factor 5/8 type domain protein; cellulosome protein dockerin type I; glycoside hydrolase family 5; KEGG: scl:sce8082 Mannan endo-1,4-beta-mannosidase" /codon_start=1 /transl_table=11 /product="coagulation factor 5/8 type domain protein" /protein_id="ZP_05430410.1" /db_xref="GI:256005447" /db_xref="InterPro:IPR000421" /db_xref="InterPro:IPR001547" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MKKRVCILLAVVILMTVSLPFVTLGADDIYPGLRVQGRFLYDKY GEKIILYGVNEMSIWGDIDGDVALPEIRKTGANAVRLVWSVSGPARKLDILLYNCRIN NMIPIIELHDATGEWQKLSMLVDYWTRPDVLEVLKKHQEYLIINIGNEVGAQVSESEF KTGYEAAVKRMREAGIHVPLMIDGSDWGKNIDILQATGPYLINADPDKNLLFSVHMWW PYMWGYNEQKVIDEIKESVEMGLPLVVGEFGHQWEEHEMGKIPYKTIMEQCYKNEVGY LAWSWGPGNQPQTFLDMTTDGTFDTLRGWGLEVCVTDPYSIMNIAVRPASMLEEPTTE PPVINIPAGSIAQNKPVYASSTEPGLGNTPEKAVDGNIATRWSSDYSDNQYIYVDLLD EYEIERVYIEWEAAYARQYKIQVSNDAVTWTDVYTEYNGDGDIDDIYLEARGRYVRIY CMQRATQYGNSIFELGVYPKGGIAEPTPPGVEILVGDINRDGKINSTDLGMLNRHILK LVILDDNLKLAAADIDGNGNINSTDYSWLKKYILKVITEFPGGDMRIVTP" sig_peptide complement(29555..29632) /locus_tag="ClothDRAFT_2271" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.896 at residue 26" misc_feature complement(28778..29515) /locus_tag="ClothDRAFT_2271" /note="Cellulase (glycosyl hydrolase family 5); Region: Cellulase; cl12144" /db_xref="CDD:159804" misc_feature complement(28229..28576) /locus_tag="ClothDRAFT_2271" /note="Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042" /db_xref="CDD:176621" misc_feature complement(order(28415..28417,28502..28504)) /locus_tag="ClothDRAFT_2271" /note="sugar binding site; other site" /db_xref="CDD:28939" misc_feature complement(28112..28174) /locus_tag="ClothDRAFT_2271" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature complement(28007..28069) /locus_tag="ClothDRAFT_2271" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 30173..31948 /locus_tag="ClothDRAFT_2272" CDS 30173..31948 /locus_tag="ClothDRAFT_2272" /inference="protein motif:PFAM:PF07833" /note="PFAM: copper amine oxidase domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="copper amine oxidase domain protein" /protein_id="ZP_05430411.1" /db_xref="GI:256005448" /db_xref="InterPro:IPR012854" /translation="MAKKLLFMALCILVFYFPLISHASANITVVVNGEKVNFTDQQPF IDSNSRTMVPIRFISEALDAKVDWIEKERMVVIKKQGTEISLVVGMKTAKVNGKEIKL DTSSVIAGGRTFVPVRFISEAFGATVEWDGKNKIVTITTKPQAGNEIGKMPESSYYNE LYNLFTLVPKGMKGSNIEQFAYYTFKEDGTVLNLNFTEEEIFKGHSFPELSKGGVIFS PSNLETVESYTVEIFKNVSRTNKQLVGQYIYFSDLKPENLMVIEKNGFTFVTTKGFKP FEIKETGYKLMSKKLFIYNDKNLYVFSFIYDPSDIKYLTESVMDSIINSIEINGTKIN LKKSTTPGKNGEVEDILPAEANYTRKMTVKENEERLKKKYFSQGFDLSDMVRIEGGTF IDENGEKVTVKPFYVSKNLVTISEWNSISKNKINIKDLNAKYNLNIKSENYPAVFETE EKYGTVKIKNNMELYVFCNEKSKSFGIEEYYTFQKTSYGTSTIFEHNGGFRLLSEDEL KYILRKTKSDAYKNNVKSNTVSEVGRSSKNEFGIFDYDSNVAEVTDFDSVLKIKDNSQ MLCGFRYAKDIGNSPQDLILDFFSN" sig_peptide 30173..30244 /locus_tag="ClothDRAFT_2272" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.949 at residue 24" misc_feature 30314..30589 /locus_tag="ClothDRAFT_2272" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature 31385..>31834 /locus_tag="ClothDRAFT_2272" /note="Fibrobacter succinogenes paralogous family TIGR02171; Region: Fb_sc_TIGR02171" /db_xref="CDD:162742" gene complement(32074..34023) /locus_tag="ClothDRAFT_2273" CDS complement(32074..34023) /locus_tag="ClothDRAFT_2273" /inference="protein motif:PFAM:PF00759" /note="PFAM: glycoside hydrolase family 9; glycoside hydrolase family 9 domain protein Ig domain protein; cellulosome protein dockerin type I; KEGG: sde:Sde_0636 cellulase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 9" /protein_id="ZP_05430412.1" /db_xref="GI:256005449" /db_xref="InterPro:IPR001701" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR004197" /translation="MSRMTLKSSMKKRILSLVIAVVFLSLTGVFPSGLIETKVSAAKI TENYQFDSRIRLNSIGFIPNHSKKATIAANCSTFYVVKEDGTIVYTGTATSMFDNDTK ETVYIADFSSVNEEGTYYLAVPGVGKSVNFKIAMNVYEDAFKTAMLGMYLLRCGTSVS ATYNGIHYSHGPCHTNDAYLDYINGQHTKKDSTKGWHDAGDYNKYVVNAGITVGSMFL AWEHFKDQLEPVALEIPEKNNSIPDFLDELKYEIDWILTMQYPDGSGRVAHKVSTRNF GGFIMPENEHDERFFVPWSSAATADFVAMTAMAARIFRPYDPQYAEKCINAAKVSYEF LKNNPANVFANQSGFSTGEYATVSDADDRLWAAAEMWETLGDEEYLRDFENRAAQFSK KIEADFDWDNVANLGMFTYLLSERPGKNPALVQSIKDSLLSTADSIVRTSQNHGYGRT LGTTYYWGCNGTVVRQTMILQVANKISPNNDYVNAALDAISHVFGRNYYNRSYVTGLG INPPMNPHDRRSGADGIWEPWPGYLVGGGWPGPKDWVDIQDSYQTNEIAINWNAALIY ALAGFVNYNSAQNEVLYGDVNDDGKVNSTDLTLLKRYVLKAVSTLPSSKAEKNADVNR DGRVNSSDVTILSRYLIRVIEKLPI" sig_peptide complement(33919..34023) /locus_tag="ClothDRAFT_2273" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.287 at residue 35" misc_feature complement(33622..33867) /locus_tag="ClothDRAFT_2273" /note="Cellulase N-terminus domain. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually catagorized into either exoglucanases which sequentially release sugar units from the cellulose chain and...; Region: Cellulase_N_term; cd02850" /db_xref="CDD:30337" misc_feature complement(32317..33612) /locus_tag="ClothDRAFT_2273" /note="Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959" /db_xref="CDD:186543" misc_feature complement(32209..32271) /locus_tag="ClothDRAFT_2273" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature complement(32104..32163) /locus_tag="ClothDRAFT_2273" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene complement(34475..35260) /locus_tag="ClothDRAFT_2274" CDS complement(34475..35260) /locus_tag="ClothDRAFT_2274" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430413.1" /db_xref="GI:256005450" /translation="MKKGLLKQFPKQIREKILDHTIESYELRDVILKLIEKNPKFIIR TYLNDEELRDLLEEKDFEMIENKLKSALNYEWLYYEFKKAVKENMDELVRDIAESFAF SILYENKYEYDESSGQIKDCGKYNLDDYEKLGDFLCDYGLVTENTDDYLEIDPDNDTS HLDSIAINYLHKTLKQLLIDVYNNRREEFLKFFGIEQDYVLSDMDFEELEYELFEFFD SDFPIPDFDNPVGIAAQLISEVEEMDAKTLFEMGKEAVMSKEK" gene complement(35313..36125) /locus_tag="ClothDRAFT_2275" CDS complement(35313..36125) /locus_tag="ClothDRAFT_2275" /inference="protein motif:TFAM:TIGR00478" /note="KEGG: gur:Gura_2037 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein" /codon_start=1 /transl_table=11 /product="hemolysin A" /protein_id="ZP_05430414.1" /db_xref="GI:256005451" /db_xref="InterPro:IPR002877" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR004538" /translation="MKKERLDVLLVNRGFFQSREKAKSSIMAGVVFVNDKKEDKPGVK VDVDSIITIKENVHPYVSRGGLKLEKAIRVFNIDLKDKTAIDVGASTGGFTDCMLKNG AKKVFAVDVGYGQLAWELRNDERVVCMERTNIRYVKPEDIGILADFSSIDVSFISLKK VIPVVINLLKDDGELLCLIKPQFEAGREKVGKHGVVRDKKVHEEVVKDIITFSLKEGL KIRGLDFSPIKGPEGNIEYLVYLSKKEGSTSEGELFELVNKVIDDSHTELSP" misc_feature complement(35391..36122) /locus_tag="ClothDRAFT_2275" /note="Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189" /db_xref="CDD:31382" misc_feature complement(35946..36116) /locus_tag="ClothDRAFT_2275" /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165" /db_xref="CDD:29105" misc_feature complement(order(35988..35990,35994..36017,36036..36038, 36042..36047,36054..36059,36063..36068,36072..36077, 36111..36113)) /locus_tag="ClothDRAFT_2275" /note="RNA binding surface; other site" /db_xref="CDD:29105" misc_feature complement(35397..35948) /locus_tag="ClothDRAFT_2275" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene complement(36188..38071) /locus_tag="ClothDRAFT_2276" CDS complement(36188..38071) /locus_tag="ClothDRAFT_2276" /inference="protein motif:TFAM:TIGR00204" /note="TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain protein; KEGG: gsu:GSU0686 1-deoxy-D-xylulose-5-phosphate synthase" /codon_start=1 /transl_table=11 /product="deoxyxylulose-5-phosphate synthase" /protein_id="ZP_05430415.1" /db_xref="GI:256005452" /db_xref="InterPro:IPR005474" /db_xref="InterPro:IPR005475" /db_xref="InterPro:IPR005476" /db_xref="InterPro:IPR005477" /translation="MDSINFPDDIKKLNLEQLKQLAGEIRSFLIEKVSKTGGHLASNL GVVELTLALHRVFNTPEDKIIWDVGHQCYVHKIITGRKDRFDTIRKLGGLSGFPKSAE SEYDAFNTGHSSTSISAALGIAKARDLRKEKYSVVAVIGDGALTGGMAFEALNDAGRS PNNLIVVLNDNEMSISKNVGGLSVYLSKIRTEPFYFKVKEDIDIILNKIPAIGKSAVK ALGRVKGTIKYMIMPGIVFEELGFKYLGPIDGHNIAELENVLTRAKNTKGPVLVHVCT QKGRGYTYAEKNPAVFHGISPFEVETGEVIANKVPGYSDVFGSEIVRIAEKEERVVAL TAAMPHGTGLIKFSKRFPERFFDVGIAEQHAVTFGAGLAKNGMIPVIALYSSFLQRAY DQVVHDVALQNLHVVFAIDRAGIVGEDGETHQGIYDISFLRHIPNMTILAPCDYNELA KMLEYAVLEHSGPIAIRYPRGAGPEKLFDTPDIKLGQSLLISEGNDVTIAAVGNKVEV AMKVAEKLKETGLSADVIYCRFIKPLDSNTIINSVLKTKRLVTIEDNTVEGGFGSRVL ETINQKGINVTTRMFGYPDAFIPHGSIKELVHMYRLDPDSIFNDVLKLINKSKVKEFR AIR" misc_feature complement(36227..38071) /locus_tag="ClothDRAFT_2276" /note="1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444" /db_xref="CDD:180086" misc_feature complement(37226..37963) /locus_tag="ClothDRAFT_2276" /note="TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products with important pharmaceutical activity. DXS...; Region: TPP_DXS; cd02007" /db_xref="CDD:73294" misc_feature complement(order(37553..37555,37559..37561,37640..37651, 37733..37735)) /locus_tag="ClothDRAFT_2276" /note="TPP-binding site; other site" /db_xref="CDD:73294" misc_feature complement(36662..37129) /locus_tag="ClothDRAFT_2276" /note="Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033" /db_xref="CDD:132916" misc_feature complement(order(36689..36691,36755..36760,36806..36808, 36815..36817,36890..36895,36902..36904,36956..36964, 36968..36973,36980..36997,37001..37003,37010..37012, 37061..37063,37079..37081,37085..37087)) /locus_tag="ClothDRAFT_2276" /note="PYR/PP interface; other site" /db_xref="CDD:132916" misc_feature complement(order(36764..36766,36770..36775,36779..36784, 36809..36811,36815..36817,36896..36898,36902..36907, 36986..36994,37001..37003,37061..37063)) /locus_tag="ClothDRAFT_2276" /note="dimer interface; other site" /db_xref="CDD:132916" misc_feature complement(order(36902..36904,36911..36913,36986..36988, 36992..36994)) /locus_tag="ClothDRAFT_2276" /note="TPP binding site; other site" /db_xref="CDD:132916" misc_feature complement(36251..36616) /locus_tag="ClothDRAFT_2276" /note="Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780" /db_xref="CDD:145764" gene complement(38102..38830) /locus_tag="ClothDRAFT_2277" CDS complement(38102..38830) /locus_tag="ClothDRAFT_2277" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430416.1" /db_xref="GI:256005453" /translation="MDDGYKHPSHEKKMKFRINILGSKNGNIRWIVLITILAFVLSSS LSFVSSNLLGDVNIFFSILIVLVIVFIGIIFDIIGIAVTSADESPFHAMASRKYYGAK QAIRLIRNANKVSSFCNDVVGDICGVISGTASAFIVFKVSQSVGGIVAFLVELSFAGF VAALTIGGKAIGKTIAIENCDYIVYKVGVIAKFLTGRFGIKKKKRKHKNRQMTNKKFK QNGQKSDDRKTNKNKNKQNKKDTV" sig_peptide complement(38666..38830) /locus_tag="ClothDRAFT_2277" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.758) with cleavage site probability 0.525 at residue 55" gene complement(39723..40169) /locus_tag="ClothDRAFT_2278" CDS complement(39723..40169) /locus_tag="ClothDRAFT_2278" /inference="protein motif:PFAM:PF02681" /note="PFAM: acid phosphatase/vanadium-dependent haloperoxidase related; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="acid phosphatase/vanadium-dependent haloperoxidase related protein" /protein_id="ZP_05430417.1" /db_xref="GI:256005454" /db_xref="InterPro:IPR003832" /translation="MKIVYSILSNKTVTVPMIAWFVAQFLKVVNVIVVERKLDFTRFI GSGGMPSSHSSFIVSLATVVGKMRGLDSVEFGISAAVAAIVMYDAAGVRRAAGKQAKV LNKLIFSQKDEDRKNFDENLKELIGHSPFEVFVGAMLGMLIGLCFA" misc_feature complement(39738..40151) /locus_tag="ClothDRAFT_2278" /note="Divergent PAP2 family; Region: DUF212; cl00855" /db_xref="CDD:154041" gene complement(40207..41103) /locus_tag="ClothDRAFT_2279" CDS complement(40207..41103) /locus_tag="ClothDRAFT_2279" /inference="protein motif:PFAM:PF00348" /note="PFAM: Polyprenyl synthetase; KEGG: glo:Glov_2183 polyprenyl synthetase" /codon_start=1 /transl_table=11 /product="Polyprenyl synthetase" /protein_id="ZP_05430418.1" /db_xref="GI:256005455" /db_xref="InterPro:IPR000092" /translation="MIKVEFKQQLEKYADIVNEYLDRCIVKNELPEKSLYSAMRYSLM AGGKRLRPVLSLAVCDMLGGSVEQVLPFACAVEMIHTYSLIHDDLPAMDNDDFRRGRP TNHKVYGEALAILAGDGLLNLAFEIMLENIIKNGDMERKSKAAAVIAKAAGMNGMIAG QVIDLESEGKQVDNEILNRMHRLKTGALIKAPVVSAAILCGADADDIQKLDEFAENLG LAFQIKDDILDVEGSSEKLGKKVGSDADNNKSTYVTVYGLEKSKEILSDVTKKAVDAL EKFGEKADFLRSLAKYLLEREN" misc_feature complement(40216..41001) /locus_tag="ClothDRAFT_2279" /note="Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685" /db_xref="CDD:173833" misc_feature complement(order(40357..40359,40372..40374,40387..40389, 40417..40419,40426..40431,40540..40542,40549..40554, 40612..40614,40621..40623,40807..40812,40825..40830, 40840..40848,40852..40860,40867..40869)) /locus_tag="ClothDRAFT_2279" /note="substrate binding pocket; other site" /db_xref="CDD:173833" misc_feature complement(order(40825..40830,40837..40860)) /locus_tag="ClothDRAFT_2279" /note="chain length determination region; other site" /db_xref="CDD:173833" misc_feature complement(order(40357..40359,40372..40374,40387..40389, 40417..40419,40426..40431,40552..40554,40612..40614, 40807..40812,40825..40827,40840..40845)) /locus_tag="ClothDRAFT_2279" /note="substrate-Mg2+ binding site; other site" /db_xref="CDD:173833" misc_feature complement(order(40426..40431,40552..40554,40807..40812, 40825..40827,40840..40845)) /locus_tag="ClothDRAFT_2279" /note="catalytic residues; other site" /db_xref="CDD:173833" misc_feature complement(order(40552..40554,40612..40614,40807..40812, 40825..40827,40840..40845)) /locus_tag="ClothDRAFT_2279" /note="aspartate-rich region 1; other site" /db_xref="CDD:173833" misc_feature complement(order(40351..40365,40372..40389,40405..40410, 40777..40821)) /locus_tag="ClothDRAFT_2279" /note="active site lid residues" /db_xref="CDD:173833" misc_feature complement(order(40357..40359,40372..40374,40387..40389, 40417..40419,40426..40431)) /locus_tag="ClothDRAFT_2279" /note="aspartate-rich region 2; other site" /db_xref="CDD:173833" gene complement(41084..41326) /locus_tag="ClothDRAFT_2280" CDS complement(41084..41326) /locus_tag="ClothDRAFT_2280" /inference="protein motif:TFAM:TIGR01280" /note="TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; KEGG: dal:Dalk_0838 exodeoxyribonuclease VII, small subunit" /codon_start=1 /transl_table=11 /product="exodeoxyribonuclease VII, small subunit" /protein_id="ZP_05430419.1" /db_xref="GI:256005456" /db_xref="InterPro:IPR003761" /translation="MKKSFEESLKELEEIVKQLEKGELPLDESIEMFQKGMMLSKDLS KMLDEMEKRVSILIEDENGTVREEDFIKMGDDKSGI" misc_feature complement(41117..>41284) /locus_tag="ClothDRAFT_2280" /note="Exonuclease VII small subunit; Region: Exonuc_VII_S; cl00750" /db_xref="CDD:186173" gene complement(41360..42595) /locus_tag="ClothDRAFT_2281" CDS complement(41360..42595) /locus_tag="ClothDRAFT_2281" /EC_number="3.1.11.6" /inference="protein motif:TFAM:TIGR00237" /note="KEGG: geo:Geob_2626 exodeoxyribonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII large subunit; nucleic acid binding OB-fold tRNA/helicase-type" /codon_start=1 /transl_table=11 /product="exodeoxyribonuclease VII, large subunit" /protein_id="ZP_05430420.1" /db_xref="GI:256005457" /db_xref="InterPro:IPR003753" /db_xref="InterPro:IPR004365" /translation="MGEFFSDNCDNILTVSAVNRYIKEIMSRDLILSNLWVRGEISNF KYHSSGHMYFTLKDENCSLKCVMFRTYNLHLKFMPENGMKVIVKGYISVFERDGQYQL YAEEMQNDGIGDLYIAFEQLKRRLASEGLFDPAHKKKIPFMPRTIGVVTSATGSVIRD IMNILDRRFYNSYIKIFPVRVQGETAALEISHAISKLNEIGGVDVIILARGGGSLEEL WPFNEEIVARSIFNSSIPVISAVGHETDYTIADFVADLRAPTPSAAAELVMPEKVTII NRIRELNVRMVDALQRNVKQKRDMLKKLADSVVFRQPYDRIYQERMKLDILNRDLKKS MFASLERAGSKLGFLIGKLDALSPLTILSRGYGIIKSEEKGIFVKSVNDVDVGEGIEV SVKDGRLYCTVRKKELNDD" misc_feature complement(41387..42568) /locus_tag="ClothDRAFT_2281" /note="exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286" /db_xref="CDD:178962" misc_feature complement(42263..42496) /locus_tag="ClothDRAFT_2281" /note="ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a single-strand-...; Region: ExoVII_LU_OBF; cd04489" /db_xref="CDD:72961" misc_feature complement(order(42272..42274,42332..42334,42338..42340, 42344..42346,42488..42490)) /locus_tag="ClothDRAFT_2281" /note="generic binding surface II; other site" /db_xref="CDD:72961" misc_feature complement(order(42287..42295,42320..42328,42347..42349, 42392..42394,42398..42406,42422..42424,42428..42439, 42467..42475)) /locus_tag="ClothDRAFT_2281" /note="generic binding surface I; other site" /db_xref="CDD:72961" gene complement(42642..43079) /locus_tag="ClothDRAFT_2282" CDS complement(42642..43079) /locus_tag="ClothDRAFT_2282" /inference="protein motif:TFAM:TIGR01951" /note="TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44; KEGG: dat:HRM2_31230 NusB" /codon_start=1 /transl_table=11 /product="NusB antitermination factor" /protein_id="ZP_05430421.1" /db_xref="GI:256005458" /db_xref="InterPro:IPR006027" /db_xref="InterPro:IPR011605" /translation="MGRRASREIAMKLIYQLEIQKDSREEQINNTLEQYDLNENDREY ILDVVKGVFKNQEEIDGTIEKFSKGWKLSRISKVDLAILRLAIYEMCHRDDIPFTVAI NEAVELAKNYSGEESGSFINGILGKVVKVKLMSADGNENRDEE" misc_feature complement(42684..43073) /locus_tag="ClothDRAFT_2282" /note="Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619" /db_xref="CDD:29565" misc_feature complement(order(43059..43061,43071..43073)) /locus_tag="ClothDRAFT_2282" /note="putative RNA binding site; other site" /db_xref="CDD:29565" gene complement(43134..43367) /locus_tag="ClothDRAFT_2283" CDS complement(43134..43367) /locus_tag="ClothDRAFT_2283" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430422.1" /db_xref="GI:256005459" /translation="MTNKEKLIEFYKSHYGEINGALTGFIFAVSILVIGFFQTVFITI CVAIGYYIGKKISQDKDYLKNLLDRILPPGTYR" misc_feature complement(43194..43346) /locus_tag="ClothDRAFT_2283" /note="Small integral membrane protein (DUF2273); Region: DUF2273; cl11575" /db_xref="CDD:159555" gene complement(43381..43929) /locus_tag="ClothDRAFT_2284" CDS complement(43381..43929) /locus_tag="ClothDRAFT_2284" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430423.1" /db_xref="GI:256005460" /translation="MNIIFRSLLAFYAFCLTVISLITMIFTLRPEMLEGASGFLVTNV LSDRGFTVLLFIIELLFFGLSLMFLLSGVKSDKDKKYISKYNNLGETRISLNTIESIA LAASRKLGGVKENKAYVKKQGDNVLIFIKTIVMPDINIPALLEDIQLKVKKSVEETTG IVVNEVKVSVENTYTGYRSRVE" misc_feature complement(43414..43668) /locus_tag="ClothDRAFT_2284" /note="Protein of unknown function (DUF322); Region: DUF322; cl00574" /db_xref="CDD:153866" gene complement(44133..44537) /locus_tag="ClothDRAFT_2285" CDS complement(44133..44537) /locus_tag="ClothDRAFT_2285" /inference="protein motif:PFAM:PF03780" /note="PFAM: protein of unknown function DUF322" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF322" /protein_id="ZP_05430424.1" /db_xref="GI:256005461" /db_xref="InterPro:IPR005531" /db_xref="InterPro:IPR005829" /translation="MGDAGQGGSNDRGTLKISEEVVAIIAGIAAMEVPGVAGMSGGIA GGIAEMLGRKNLSKGVKVEVGDKEAAIDLYIIVEYGCRIPEVSWNIQEKVKKAIETMT GLNVVEVNIHIQGVNIEKEHKKDSDEEQARVR" misc_feature complement(44190..>44393) /locus_tag="ClothDRAFT_2285" /note="Protein of unknown function (DUF322); Region: DUF322; cl00574" /db_xref="CDD:153866" gene complement(44638..45285) /locus_tag="ClothDRAFT_2286" CDS complement(44638..45285) /locus_tag="ClothDRAFT_2286" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: WD40 repeat-containing protein ; K11795 nuclear receptor interaction protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430425.1" /db_xref="GI:256005462" /translation="MMVLKRKQIVVLSLILMIVVAGYLQYSYNNSGSSGNDSDDISVS QFDEETESLGEAWYVDNTTDLQAGNKEEKKDEKSENSDKKENKQDNKALQASKEANEF FAQAKMDKDVRRAKDKEELEKITNDANATEEQRTQAYERMLKLLENSDKEMRIEALIK NKGFSDVVVFFGDDGSVDVVVKAPSISSVEVAQIAEITSRQAGVDISDVHVSNKF" sig_peptide complement(45196..45285) /locus_tag="ClothDRAFT_2286" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.619) with cleavage site probability 0.222 at residue 30" gene complement(45392..46015) /locus_tag="ClothDRAFT_2287" CDS complement(45392..46015) /locus_tag="ClothDRAFT_2287" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430426.1" /db_xref="GI:256005463" /translation="MGKIKETIERLKNMLDKDKNNKWGENLVILIIIGMIIIIAGGTL FGGNDKKKDENKVKSSEALDNTREVLNIGVDDEKSDLEKDIENILEKIQGVGKVSVMI TYASGKEIVPYTDVKRSDNSTNEKDSAGGTRRIAQSSYESSVVYEESDKGVKKPIIAK ELMPEVKGVLVVAEGASDATVKENLVNSVKVLLDIPVHKIQVVERGK" misc_feature complement(45404..45874) /locus_tag="ClothDRAFT_2287" /note="stage III sporulation protein AG; Region: spore_III_AG; TIGR02830" /db_xref="CDD:163038" gene complement(46026..46658) /locus_tag="ClothDRAFT_2288" CDS complement(46026..46658) /locus_tag="ClothDRAFT_2288" /inference="protein motif:TFAM:TIGR02896" /note="TIGRFAM: stage III sporulation protein AF; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="stage III sporulation protein AF" /protein_id="ZP_05430427.1" /db_xref="GI:256005464" /db_xref="InterPro:IPR014245" /translation="MIDFLRNWVVNIVTLVVFVMLIEMMLPSGKVKKIVNLVTGFILV IGLINPVLELFEKEIDLKEFQLAGSNYIDKKEVMINSEVLEERQIRQITNAYREKIIA QLKSVAKDIKEVKEAEADVIINEDYTSERFGEVKKVYLYLSLEDESEQVKHILEVKRV KVDIGQSVDNSDNKGLEKQPDEKIRRELEDKVIKLLNVPKENIVISLMED" misc_feature complement(46041..46622) /locus_tag="ClothDRAFT_2288" /note="Stage III sporulation protein AF (Spore_III_AF); Region: Spore_III_AF; cl09803" /db_xref="CDD:158705" gene complement(46681..47910) /locus_tag="ClothDRAFT_2289" CDS complement(46681..47910) /locus_tag="ClothDRAFT_2289" /inference="protein motif:TFAM:TIGR02829" /note="TIGRFAM: stage III sporulation protein AE; KEGG: hypothetical protein LOC769970" /codon_start=1 /transl_table=11 /product="stage III sporulation protein AE" /protein_id="ZP_05430428.1" /db_xref="GI:256005465" /db_xref="InterPro:IPR014194" /translation="MKNKRYYAKCILVFVFVTVFTSMCFVSLPAYAAGEDETYAQDKS IEEKIMEEQIEADEVDLLEKELKKYKDEKIDEILPGYDPEKIIRDVAKGKLNFNLPDI INKILTYLFEEIYLNMGILVKLMVLVALCAILNNLQSSFLNKGVGELAFYVCYIVLVS ILLVSFSSVVKSGTEIIDRMVNFMYSSIPVLVTLIISSGNISSGGVLQPLLIMVVQVS ATIIKNILIPLIVLSTIISIVDNISDKIQISRLSSFLKNITQWTLGLILTIFVAIVSL QGSLGAVVDGVTSKTAKFAIGAFIPVAGKYLADAADAVIGCTLLIKNAVGVAIMIGIV VICLLPLLKILAVVLLYRMACVLLEPLAEGRIIKCISDVAGSMAHILGIAASVAFMFL MTVTALILASNISTMIR" sig_peptide complement(47812..47910) /locus_tag="ClothDRAFT_2289" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 33" misc_feature complement(46696..47676) /locus_tag="ClothDRAFT_2289" /note="Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; cl09771" /db_xref="CDD:164148" gene complement(47975..48364) /locus_tag="ClothDRAFT_2290" CDS complement(47975..48364) /locus_tag="ClothDRAFT_2290" /inference="protein motif:TFAM:TIGR02849" /note="TIGRFAM: stage III sporulation protein AD" /codon_start=1 /transl_table=11 /product="stage III sporulation protein AD" /protein_id="ZP_05430429.1" /db_xref="GI:256005466" /db_xref="InterPro:IPR014211" /translation="MEIFQIIGLALVATVIALLLKAHRPEMALQISLVTGIIIFLVIL GKITAVVDLLSSYAEKVNIDMVYINTLLKIVGIAYIAEFGAEVCRDAGEGAIASKVEL AGKVIIVVMAVPIITSLLDLIISILPQ" misc_feature complement(48023..48286) /locus_tag="ClothDRAFT_2290" /note="Stage III sporulation protein AC/AD protein family; Region: SpoIIIAC; cl05961" /db_xref="CDD:156954" gene complement(48390..48584) /locus_tag="ClothDRAFT_2291" CDS complement(48390..48584) /locus_tag="ClothDRAFT_2291" /inference="protein motif:TFAM:TIGR02848" /note="TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation AC family protein" /codon_start=1 /transl_table=11 /product="stage III sporulation protein AC" /protein_id="ZP_05430430.1" /db_xref="GI:256005467" /db_xref="InterPro:IPR009570" /translation="MNIDLIFRIAAIGILVSVLNALLNKSGREEQAMMTTLAGLVVVL MMIVKEIANLFDAVKTLFQF" misc_feature complement(48393..48584) /locus_tag="ClothDRAFT_2291" /note="Stage III sporulation protein AC/AD protein family; Region: SpoIIIAC; cl05961" /db_xref="CDD:156954" gene complement(48687..49208) /locus_tag="ClothDRAFT_2292" CDS complement(48687..49208) /locus_tag="ClothDRAFT_2292" /inference="protein motif:TFAM:TIGR02833" /note="TIGRFAM: stage III sporulation protein AB" /codon_start=1 /transl_table=11 /product="stage III sporulation protein AB" /protein_id="ZP_05430431.1" /db_xref="GI:256005468" /db_xref="InterPro:IPR014198" /translation="MLLKIIGSLIVFMSSSLLGYMYSRRCSKRPAELRALQGYLQMFE TEISFMSNVLKDAFTKIYMYDDSSVAVFFKGTVEALENDTGITAGEAWAKAVKENIKN TSLNKEDEEIIISFGKMLGSSDVEGQIKNIRLTINQLKLQEQKAEELRAKNEAMYRNL GILGGLAIIIILF" sig_peptide complement(49149..49208) /locus_tag="ClothDRAFT_2292" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.883) with cleavage site probability 0.865 at residue 20" misc_feature complement(48732..49199) /locus_tag="ClothDRAFT_2292" /note="Stage III sporulation protein AB (spore_III_AB); Region: Spore_III_AB; cl08022" /db_xref="CDD:186736" gene complement(49211..50221) /locus_tag="ClothDRAFT_2293" CDS complement(49211..50221) /locus_tag="ClothDRAFT_2293" /inference="protein motif:TFAM:TIGR02858" /note="TIGRFAM: stage III sporulation protein AA; KEGG: Os07g0187400; hypothetical protein" /codon_start=1 /transl_table=11 /product="stage III sporulation protein AA" /protein_id="ZP_05430432.1" /db_xref="GI:256005469" /db_xref="InterPro:IPR014217" /translation="MVTKEDFVFSVEKVQNFEKDILRMISPQVRDVLKKIPLNELITT EEIRLRANKPLMIQNEKGSFFVNLEGRLTANRMNLFYVSQEQIAKTLELISENSIYAF QDEIRNGFLTIRGGHRVGIVGRVVLNGDTVKNIKDVSGLNIRISREITGCSSKVLKYI ISSEKQVYNTLIVSPPQCGKTTLLRDITRAISDGVEEMGFKGVKVGVVDERSEIAACY KGVPQNRVGTRTDVLDACPKQIGMIMMLRSMSPDVIVTDEIGNKGDKDALIQVLNAGV KVISTAHGYNISELKSRKEVLSLIEEKMFERYIVLSARKGPGTVEEIIDGTDMSILYK GE" misc_feature complement(49244..50089) /locus_tag="ClothDRAFT_2293" /note="stage III sporulation protein AA; Region: spore_III_AA; TIGR02858" /db_xref="CDD:163043" misc_feature complement(<49583..49711) /locus_tag="ClothDRAFT_2293" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature complement(order(49679..49687,49697..49702)) /locus_tag="ClothDRAFT_2293" /note="Walker A motif; other site" /db_xref="CDD:29986" misc_feature complement(order(49598..49603,49607..49609,49679..49687, 49697..49699)) /locus_tag="ClothDRAFT_2293" /note="ATP binding site; other site" /db_xref="CDD:29986" ORIGIN 1 taaaaacaca ggcaaaaaat cctgtgttct tttttaaaat tctatatttt acctgccaat 61 ttctcggcaa caatcttctc accaatttca gctttcttgc ttctttctgt tacaacactg 121 caagaataat tctttacatc tctgggtctt gcatcccgtt ttacttttct tccctcaaca 181 agttttttta atggtgaact aactccctgg gtcattttac aacattccct atatttatat 241 tatatcttaa atttcaaaaa aattcaatta ttcctcctta gtagcaatat ataactctgt 301 atcaaatatt gaaacaatat tttgaataat taaatgctca tatacaaaca aacttccttc 361 attacttttt attaccacca acaaatccgg aaacacaaaa gatgttgtaa tatgcgcata 421 aattactctc agttcgtcct gaggcggaat acaaacacca ttaactaata atgaatattg 481 aatggctgaa aactcaacat cagacaaatt attatttttc tttgacattt gtcttttcct 541 caatatattt ttcaacttcc ttcatcagtt ccggatcaac ggcttcccct cctcaacctg 601 tctgagacat acaaaatgtg agctttgccc tctcttcggt actgtttttc tgtgtctctc 661 catctttttg gcatccggca aagaggtaag ccaacatcag caagcagagc aaaagtatag 721 agaccttttt ccgagaatac attttttgcc ctctttttaa cagctttcca ctcttaattt 781 tattctacaa taaaaacgct tttcaagcaa aactgccgct ttaagctgat ttatcctttt 841 aaatacacgg gccttgaatt tttaaacggg ctgtaataat atttatatgg tgatagcatt 901 tgaatctaaa gtatacagtc gataaagaaa cttcgggcaa aaccgtaaaa catatactga 961 aaaagcagct aaagctttcc gaaaggctta ttaaaaagct aaaacgtcaa ggcaaaattt 1021 tgtgcaacaa ccgtcctgtt tatgtcaatg ccgttgtatg cgaaaacgat ataatcgaag 1081 ttgatctcga ctttgatgat tcgggtattt ttatccaacc cgaagacata cccatagata 1141 taatctatga agatgaattt cttattgctt taaacaagca gcccggcatc gtggttcatc 1201 cgacatgctc acaccccggc ggcacccttg ccaatgccgt ggcatttcac cttcagaaaa 1261 aaggaattgt aaaaaagatt cgcccggtta taaggctgga cagagatact tcgggcatca 1321 tcatatttgc aaaaaatcca tattgccagg aatttctcat tcgccagatg aacgacaaaa 1381 ctttcatcaa agaatacatt ggcattgtgc acaaggtatt ggaaaatgac aacggaacaa 1441 tagatcttcc cattgccaga aagcccggaa gcattatgct taggcacatt tctcctgacg 1501 gtgatcctgc cgtgacacac tacacggtac ttgagcgtct taacggcgcc accctggtaa 1561 aattcagact ggagaccggc aggactcatc agataagggt tcactgccag gcaatcggtc 1621 atccccttct gggtgacact ctgtaccctt ttgaagatac tccatactct ctttcgggaa 1681 ataaccccca tattacccaa gccaacactc cttccataac ttcgggaatt atcacaaggc 1741 aagcacttca ttcccaaaga gcagtctttt tgcatccttt tacaaaaaaa atccttgaaa 1801 ttaccgctcc tatacccgaa gacatgaaat ctgctttgga aatattgaga aaataatcgc 1861 ccaaacattt acacaataag gtattggtgt tattatagta cttgccttca ttataaaggt 1921 attatttagg ttaagcctct tggtccatgc gtcctgttgg ctttatcgcc ggctgtacgc 1981 caaaaatgaa tgggctttat atttctggaa agtgtaattc taacctgctt ataatatgct 2041 gcaaaagaaa cggaggtatt tacgtggaag ttataaaaga ccgttattct atcacagaac 2101 ttagcggata tcttaatgtt accgatcata ccttaagata ttatgagagg gagtttaatc 2161 tgtatgtccc aaaggacaaa aggggcagga gatactacac tccggagctt gccaatatta 2221 tgtacaagat taagaccatg agggatgaag gacttgaaat taaagccata aaaaaaattc 2281 tccaatcgga gaatgtaata acggagcctc caccggtcgt aaccgaggat attagtgtgc 2341 ctgttgcaaa gcataattac ggcgaaaacc tcgttgatat aaaaactttc tttcaggaat 2401 ttgaaaaaca actgaccaac agcgtcgccc tcgaggtaga gctggcaaaa gaacacatga 2461 ccaacgaact taataaaaca aagcttgaac tgggtgcatg tctcgaaaac aatatcagac 2521 gacttgagag caagcttgac aagcattttg aaaatgttga ccgttccata tcaatgtgga 2581 gggaaaaaaa caaagacagc ctcttaaaac gcctcaaaaa aaaggttttc aaatagcaaa 2641 ccgaacaaaa ggggcatttg cttccccttt tgtctttata tgctattttg tttcacactc 2701 gctgattagt ccaattctct ttaaaacttc ggtaaacttc tttgtgtcta tgggctttgc 2761 cgcataggcc tcacatcctg aatcaaaagc gttatagaca tttgtagtgt catttaaggc 2821 cgttgtcatt ataactttga cccgactgtc tccttcaatt cccctttgct tttccacatc 2881 ccttattgcc tttaaggccc ttgttccgtc aagctttggc atcataatat cgaggcatac 2941 caggtcatag ggttttcctt cgtcaagagc gagcataaat gcatctactg cttcaattcc 3001 gtctattgta atgtcacatt ccccgtaggc ggaaagaaac ttgtacaaaa acttcctgct 3061 tgcatagtcg tcttctgcaa taagtatcct catattataa cccctttcca tggatatttt 3121 tgtatgtgtt taattcttga attaattaaa tttgctgatt tcctgcttta gcacctcata 3181 cagttttttg acatcctcta gctgattttt cctggcagaa agttgtattt tgaacgcaag 3241 attttttact ttgtcaaatc ctctgttttg tgcaaattct tttactgcca aagcactctt 3301 gtcaattgcc gtaaagtttc cattcagtat ggaaagatcc agtcgttcca ttatatcttt 3361 caaactataa tccggacccg tttcatttac agttccactt tcagataaag tttcattaac 3421 tttttcatcc ggatccaaac ttcctttttc atcttctttc tctttttgca tatcatcact 3481 cgattgctca tctttgtaca gcactctgtt tattgctgca taaatgtcat caaaggaaaa 3541 gggttttgaa atgtaatcat ccattccggc ttccaaaatc ttctccctgt cattctcaaa 3601 agcaaatgca gtaaccgcaa taatgggaat gtgcctgaaa gttccttctt ccatttttct 3661 tattcttttt gtcgcttcaa taccatccat ttccggcatt tggacatcca tcagtataag 3721 gtcaaactca ttttcttcga agagtttaat tgcctcaaaa ccattttcag caattgtaag 3781 agaacattgc tcttttttca gcatgcctgc tataacctgc tgattgacct tgtcatcttc 3841 ggcaagaaga atgttgagtt tcctcccaag tacccgctca tcggcatttg aagtacactc 3901 tgccttaaca ctgcttttgg cttttctttt aaaacctgca gtaaaataga aagtgcttcc 3961 tttccctttt tgactctcta cccagatttc gccacccatc atctctacaa gctgttttga 4021 aattgcaagt cccaagcctg tacctccata ttttcgggta atggagctgt caacctggct 4081 gaaactttta aacagcatgt tcatcttgtc accgtctata cctattcccg tatctgacac 4141 agtaaatttc aactttacag aatcatctct tttttcaata atatccacat ctattcttac 4201 ttcgccgata tcagtaaatt ttacggcatt ggaaatcagg ttgtttaaaa cctgctgaag 4261 ccgtccggga tcccccacca aaatcctcgg tatgcctttt tgcacagtgt agcttaatct 4321 cagtcctttt tcgtttgcct gtacaatatg ggctttgtat gtcttttcca aaaggttgaa 4381 gaaatcaaac ttgacatttt ctaaagtcat tttgccggct tctatcttgg aatagtccaa 4441 aatatcgttt ataaccctaa gaagcagttc cgcacatgaa tttacaatat tgaggttttc 4501 cctttgctca tcagttaatt ctgtctgtaa agtaaggttg gtcatcccga ttattccgtt 4561 taagggagtc cgtatttcat ggctcatgtt tgcaagaaat tcgctttttg ccctgtttgc 4621 agcctcggca gcttcttttg ccttgaaaag gttttccgac attaactttc tttcagtaat 4681 atcttcggaa actttaagat aattagttac gacaccttcc gagttgatta tcggagaata 4741 atatgcatat tcccaaaata ccacattgtt ttttgattta tgcctgattt cacttctcca 4801 ttccttgcct gaaaacactg cctgaatcat atctttgcat ttttcttcgc cattttcttc 4861 taactccatg aaaaaaaggc tttttccctt tacctcatca aagctgtatc ctgtaacttc 4921 agtaaatcgg ggatttacat attcaatatt tccacgcgtg tctgccatca caatgatacc 4981 gggactttgc tccactgcct gggataattt ctgaagcttc tcttccgctt ttcttatcct 5041 agttatgtct ctgaaaacta caacaacacc cattatttcc ctgtcagaac tttttatcgg 5101 agcggtgctt gccgaaacat accttaaagt accgtctttt gaaaccagca tggtattttt 5161 cctaaggccc acggtcttcc gctcggacaa taccctctca tagggatcgg gctcaggctc 5221 acggtttaca ccgtttatta tcacaaaaac ttccgacagc ggtttcccaa ttgaattaca 5281 ggacaaatac cctgtcagtt cctgggccgc tttgttcatc atgattacac aacccgcctt 5341 gtcggtaaca attacgccgt cccctatgct ttccaaagtt gttaacagtc tttcattttc 5401 ctccttcagc cttttttcaa accttattcg ttctctttcc cgttcaagct cccggcatct 5461 tttaaatata atggatctta gccttgagga atctttcttt tcgagatact cacaggctcc 5521 cagttttatc atttcaaaac catgcctact tccgtcttct tccaaaactg caacaacggg 5581 catttctttt ttaagatttt caaaactctc catcacatcg gcaaaagaaa tgtcagaaga 5641 acagtcaaaa aaaacaatat gaaaattatt ttttcttaaa tagtttttaa attcattaaa 5701 tgtagcagca ctttttacgg aatgcttgca ccccacgtcc aaaagagcgt tctttaggga 5761 tgctgcaaac tcctcgtcat ttcctgccac catcacctcg aggttcacat tcaaatcatc 5821 cctcacctcg ttttttactc tgcaatccat acttccaaca gtctgttaca acattgaata 5881 taccaattgt ggtattgctt ccaaagaaac ctgcttttca acggcgccaa tttcaaaggc 5941 aacttttggc ataccgtata caacgcagga tttttcatcc tgtcccaatg tcctcgctcc 6001 tttttgtctc atggccaaaa ggccttttgc accatctttg cccatgcctg taagtattat 6061 gcctatggca tttttacccg caacttcggc aacggaatta aaaagcacat ccaccgaggg 6121 acaatgtccg ctgacctttt ctcctttggt acactcgact atataacctg aaccgctttt 6181 ctttattgtc atgtgatgat cccccggtgc aatcaagact cttccctggc aaactctgtc 6241 tccggtctga gcttctttga cttccataag gcacgaattg ttcagccttt ccgcatacat 6301 tctggtaaat accgggggca tgtgctgaac aataacagta cccgggatgt ccctcggaaa 6361 cgctctgagc agattgtata tcgcctcggt ccctccggtg gaggcaccaa tggcaatgat 6421 tttgctcgag gcttctctgt tcatgcttcc tatggttttt aaatcagcat actctttttt 6481 ccagtgtccc acttttgcca ttgaagcaat ctttatcttt ataatcaatt catttatcaa 6541 aaagtcaaat cctctttggg ttgacaaatc cggctttgta acaaaatcaa cggcaccggc 6601 gttgagagcg tcaaacacat tgtggcttac agcacttact accacaacag gaataggata 6661 ttgaggcatg agccgcttta gaaattcaat cccgttcatt ctcggcatct caacatccaa 6721 ggtcataaca tccggcttaa attcaataat cttgtccctg gcttcataag ggtctgatgc 6781 tgttgctaca acttcaattg atgcatcctg agctattcct tttgaaattt tctctctgaa 6841 caaaagagaa tcatcaacca ccaaaacttt gatttttctt ttcatgttgc tggttctcat 6901 agtattcaag ctctatctat tcctttctgt aaaccgccgg cattacatat ttgtatttgg 6961 tttcatcccg gtttaaagat tcggaatggc cgataaacaa atatcctccc ggctcagtat 7021 actcatagaa cctgtttacc agttccattt tggtttgttg gtcaaaatat atcattacat 7081 ttctgcagaa tatgacatga aactttcttt taaatgggaa gacagtattc ataagattaa 7141 aaatcctgaa tattacctca tttcgaatac tgtccaccac ggcccaattg ttttcgtcta 7201 cctttctgaa gtactttctt ttccacgctt caggaactcc ttcaatcctc tcattggaat 7261 aaattccagc tttggctttc tgaatcacat ttactgaaat atctgttgcc aaaattctcg 7321 tatcccataa tggcttttga ggaccaaaga agtctgctat tatcattgca agagtataag 7381 gttcctcacc gctggagcag cctgcactcc atatcctaag gtccagcggc ctttttatag 7441 tggcagaaag atacggcaac acagttgagg caaaaaaatc aaagtgatcc ggttccctca 7501 taaagaaagt atgatttgtg gttatcttgt ttataagtgt tgttaccgct tcgccggttg 7561 tatcggacat aacataatca tagtaatccg aaaaacttgt gaaattcatc tgctgcaaaa 7621 tattttgaag ccttcccaca accaatgtct ttttcttttc cgtcaggttt attccatagt 7681 tgctttttac ataagcggca agctggtcaa attctttttt gctaatatgc aacatatcat 7741 ctcaccggct acctcatttt ttatatattg agcaaatttt cacaatcttc gtcatttaac 7801 agcttgttgc agtcaagcag aagctttact tcatcgccga cctttccgat ttgcttgata 7861 tagcggttgt taaaaccggt attggcttcc ggaggaggca ctatattctc ttccggaatg 7921 gataccactt ctgcaacact gtccacaata aggcccacgg aaacatcttt tatgtcaaca 7981 actataatgc atgtcctgtc attgtactcc attggctctt ttttaaatct aagccttaca 8041 tctaaaacag gtatgatttt cccacgcaaa tttataatac ctttaatata ttccggcagc 8101 tcgggaactt cggttatctg ctgcatgccg attatctccg taacatactt gatttctatt 8161 ccgtatactt ctttcccgat aataaatgtt agatatttgc ctttttgagt atcttcttcg 8221 tattccaaaa cattttccaa agcttcactc ataaatagat ccctcctact agcttactaa 8281 ccctgcaaca tccaatatca ggcttatgct tccgtcacct aaaagcgtac aacctccgat 8341 accttttact ttctttatat actttggcag tgccttgact accacctgtt gttctcctaa 8401 aagttcatcc gcaaatatgc atattaccct ggagtcgctc tcaaccataa caattattcc 8461 gtcatttata tttgtaacct cagtgttgat tttatagaat ttgtgaagtc tcaatacagg 8521 ataaacctct cctctgacca tgatcatttc attgccttca gagtctgtaa ttacagcttc 8581 gtttttcact ttaaaggatt ctttgattga tatggtcggt attgtatatc tggattttcc 8641 gactttgata ctcataccgt tgataatggc cagtgtcaga ggcagcttta tggaaattgt 8701 cgttccatta tccggcacgc tgtcaacaaa aatcgttcca cccaccatgg agatgttgtt 8761 gcttacaata tccattccca caccgcgccc ggaaaattca gtaacatttt cctttgttga 8821 aaagcccgga gtaaaaataa atgaatatat ttctttatcg gtaagctcgt tttccggttt 8881 gtgtataagt cctgcttctc ttgctttttt aagtattttt tcccggtcaa gtcctcttcc 8941 gtcatccttt acaaatatcc atacatcccc tccggcattc tttgcctcaa gagtaatctt 9001 tcccgccgga ggttttccct ttgccaccct ctcatcagga tcttcaagcc cgtggtccac 9061 ggcatttctt ataagatgaa tgagggggtc ggatatacgt tcaataatat ttttgtcaac 9121 ttcggtttcc tctccgatta tctccagctc tattgacttg tttaatttct tacccatgtc 9181 tctgactatc ctgttcatct tttggaaagt cattgaaagg ggaaccattc gaattgacat 9241 caccacatcc tgcagctcat ttgtcaactt gttgagctgt cttgctgcct tgtgaaaatt 9301 gtcgagctga aggccctcaa gatcgggatt ctgcgttacc atggcttcgg agatgactat 9361 ttctccaacc aaatccatta atttgtcaag tttcgctatg ttaacactta taacactttg 9421 cttgcttgaa gatgcagtat tatctgccga cggacctgtt ttcttctcat ttgaaagctg 9481 tctgccggaa gaatgctcgt tttgctccga agcttgagaa gaatcattca aaacattagc 9541 tttcccgtcc attttcagct tttgctcttt tagctcagtt tcccgggtat ccggcatatc 9601 gcccattata tcctcaagat cttcatttat tacataaacg tcgaggcttt tgagcaaaat 9661 ggtatgggac agtctttctt ttacctcgtc aagtcctaaa tcggtactga acaccaccct 9721 gaagccatct ttctggatga tctcactatt ttcacttttt ccgccgccgt caatgacatc 9781 ctcagggtag aaataattca catcggctat ttcctttaag tcatgaatta cggaaaatgc 9841 cctgatgttc tccataccgc actgttcttc aaatttaagg acggcttcgt atttatgact 9901 tttgggagtt gacgccgctt tatttgagct tatgtaatat ttttggtctt tttcaacttc 9961 caaagtatga gatgactcag aatcaggaga atcacttccg gcattattta tactttttaa 10021 attacccaga taatccctta tttcttttat aaggtcagag gcatctccgt ccggttcctg 10081 tccgttttca agtttaacgg tctcattttt tataaagtca actccgttca gcacaatatc 10141 aataatttct gtcgaattaa cattttcagg cttttcttcg cgaaggtaaa agaacagatc 10201 ttcaatagaa tgggcaagtt ttgatatatc gtcaaaaagc atcattgccg ctgagccttt 10261 tattgtatgc atgattctga aaatctcatc tatcgaagat tcaaacccac tttctttttc 10321 actgttaatc aaagactgct ctaactgatc caataactgg agtgtttcaa atataaacat 10381 gtccagcatc ggctcacggc taacattatc agtcaatttt tccacctcca tgtgtttata 10441 ttactacttc catgctatta taatttttca atagcctgta taacataatc ttctttgaaa 10501 ggttttacaa tgaatccttt tgcacctgcc aaaattgcgt cccttacaaa gcactcctgg 10561 cccatggaag aaatcattat gacttttgca tcgggatcaa actctttaat catcttaacc 10621 gcctttatcc cgtcacatac cggcatggtt atatccatcg taactatatc cggcctgatt 10681 tccttatatt ttgtgaccgc aaccaaaccg ttttcagctt ctccaaccac ctgatgtcca 10741 tgtctttcca acatcatttt aagtgacgcc ctcataaatc ccgcatcgtc aaccactaaa 10801 attcttttca tttcctcaca ctcccacgtt tttagttttg ttgaatacta aatctcatgg 10861 tttaaaattg tgttatttcc ccttctatat tggaaattta gaataaacaa tcacaagact 10921 tgcgctcccc tctttttatg aacaaatcaa gatgtgtata tttgaccaat aaaatacttt 10981 atataaatat tatgttatta tttttcaatt taatcaagta aaaagtttta tttgatgttt 11041 atatcgaaat ctataatact attattaaca gtaaattttt attattttgt agaatatcat 11101 gttgaatacc tcgtaatcac ctaaaaaact caggaaattg acatgactaa aatccgctaa 11161 aataatcaga tttttaaagc caacataaat gaagcagtaa taaattctaa gcttataact 11221 taaaatttat tactgcttcc acaccttatt actgttttgt atttttttgc attttttatt 11281 gttttatgta gccattttca tttccaatct caatttgtct gccaccattg ctataaattc 11341 cgaatttgtg ggtttacctt ttccaacatt tatcgtatag ccaaacaacg aatctattgt 11401 atcaatctgt cccctgctcc acgccacttc aatagcatgt cttattgccc tttcaactct 11461 gctgggtgtg gtgttgtatt ccttcgctat tgtaggatac agctgctttg taattgaatt 11521 tatcacgtca aggtctttga ctaccattat tatggcatcc ctcagatact gatacccttt 11581 tatatgggcc ggtacgccta tttcatgcat aatatttgtt acttcagctt caagattttt 11641 tggctgcgga ggatgataag acgacttgac ttcaccggac aaaccgtcct gtcttataac 11701 attgggctgg ttcacgttct tgagttgtct tattctcgaa attaaaactt ccatgtcgaa 11761 aggctttaca acatagtatt cagctccgag tgccaatgct ctttgtgtta tcttgtcctg 11821 gcccactgcc gaaagaataa tgaacaaagg tcttttactg attgcagtcg cgcctatttt 11881 ctccaaaaca cccaaaccgt ccaaatgagg catgataata tcaagtatag caatgtcagg 11941 aagtttttca actataagct cataagcttc aataccgtct cttgccaccc ctaccacttc 12001 aatatcttcc tgattgttaa ggtattcata taaaatatcg ccaaattccc tgttatcatc 12061 agcaattacg acccgaatct tatttgatgt caaattgact cccccttaat tttttgtaaa 12121 agactgctag ttaatttata ccattattat attgtctatt cgacaaaatt tcaatatact 12181 gggtaatgaa attactcttt atataacttg ttttacattt ataatactat ataatcattt 12241 actgtaagta ctggtatttc tggattttgt gacataaaga aaccttttat gaattttttt 12301 attctaaaag caatatctta aaattttttg gaaatatgca aaacccggga aatatgcaat 12361 ttatgtaaaa tatgtgtatc ctccttacga aaatacacat atttttataa tcttacaaat 12421 ttattatttc gttaatcttt cttcttaaaa aactttttaa gaagcattgg ccatttcaac 12481 attttgcaaa tttgcatcag ccatgttttt aatcatccac tcaatcagta tgccatagcc 12541 tcttgcaggg tcattcacca gtacatgggt tacagctccc accagtttgc catcctgtaa 12601 aatagggctg cctgacattc cctgaacaat acctcccgtt gcctcaagaa gtctgtcatc 12661 agtcactctg ataaccattc ccttcaaacc attggcgctt tttcttgaaa ctttttcaat 12721 ttcaatactg tattcttcaa cttttttgcc gtctatattg gcaagtatgg tggcaggtcc 12781 cacctttata tcgtttctca aagctatagg atattttacg ttcggaaatt tatccaacgc 12841 cgcgtcattc aaagtaccat atatgccata atggctgttt ttcactattg ttccaagaac 12901 accgctgtct tctatcaata cacctttaag ttccccggga ttgcctttgg tacctttttt 12961 tacggtcaaa atatttgatt cgacaagctc acctctttga acgggcataa tggctcccgt 13021 atcaatatcg gtgattccgt gtcccaaagc cccaaagcct ttagtcacag ggtcgtaaaa 13081 tgtcaacgtt ccgattcctg ccgtgctgtc tctcacccac attccgacac ggtacttatt 13141 gtcttcagcc gatttgaccg gcgttacttt tgtattgttg tagctgtttc ctctcttata 13201 ttttacccat atgttttcgc ccatgctatt ttctacttca ttcattaaat catatgcagt 13261 atcaaccttg ttgttgttca cttcaacaat aaggtcaccg ggtttcagtc cggaatctct 13321 ggccggaatc aaccttcttc catccggggt ttcaacatcc gacaatccaa tgacgagtat 13381 accgtccacc tttattttca cccctactgt atttccgcaa gccacaacct ctttatacgg 13441 gacaacatca acatacatgg tttttaaggg aatgagtccc aaaagcttta agctaaggct 13501 tgttctgcca agtttgctgg ctttgaacat tactttgttt ttggtatcct tataatcatc 13561 attattgatt tttatgtctt cgctgtcaaa tatcaatatg tcattattat ctgatttaaa 13621 gtttacaagg tttacaagaa gcgggctttt gaatttataa atatattcct ggttttcaaa 13681 caatgtcagc tggtttggaa agacggaaat taatcttata tatgctatgc tcaaaattgc 13741 ggcacaagcg ctaaaaaaaa ttataagttt tttttagcgg gttttataaa tttcaaaagg 13801 atcaccctcc tggtgtcttg ttggaaaaat aaaaaacatt ataaaaaata tcaacacaaa 13861 ttgattgttt tccccttgat tactaacatt aaattaacct ataataactt tatttattca 13921 ctaaaaaact ctgaaataat gtaaaaaaac agtaaccgat ttcacataaa agttcgcgca 13981 acaaaataaa aaagcccggg attgtgattc tcccaagctt tttatctata gaaaaactta 14041 tttcttaaat tcttttgctt tgtcaagcat ttcttcagca tgctttaatg ttatgtccgt 14101 aatactcgct ccaccgagga tccttgctat ttcgtccctc tttccccttt catcaagctt 14161 tttaaccacc gtcctggtat tgccgttttc ggttaccttg tcaatataat agttattgtc 14221 cgccatacag gctatttgtg ccaagtgggt tacagatatg acctggtggt ttttcgaaat 14281 ataacagagc ttctctccca ctttttgagc cgcaacaccg cttattccaa tatcaatctc 14341 gtcgaatatc attgtgggta tcttgtccac ttttgcaaga attgtcttta ttgcaagcat 14401 cactctcgac atttctccgc cggaagctat ctttgccaaa ggtttcaaag gctctccagc 14461 gttggtggat atcataaact ccactctgtc aagaccgttg ttattgtatt ttctttcccc 14521 attctccgtt gaatcgtcaa aatctattct caccttgaaa ctggtgtttt tcatttccag 14581 gtctttaagc tcctcgccga ttttttcttc gagaagcttt gacgccttaa ccctttcatt 14641 gttcatttcc tttgccagtc ggtacagctt cccgtcttct tccaaaagct cttcatttaa 14701 cttatttaca atttcttcat tatttaaaat ttcatccagt tccttttcta ttttatcctt 14761 gtactctaag atttcttcca ccgaatctcc atatttcttt ttaagcctgt ataatacatc 14821 aagtctgctt tcaatctgca taagaaggtc tggatcatat tccatattat cgcgcaaatt 14881 gcggatttcc gagacaatat catcaagttc aatcgcaacc gcctcaatcc tttttttaag 14941 ttcatcatat tttgcatcaa actcctctat accgccaaaa tccgaagcag ccttgtttat 15001 catgtccagt gcggattctc cgaatttgcc tccgcttcct aaaagttcat aggcattgga 15061 aagagtgttt gtaatttttt cagaattcac caaaagttct ctctgttttg aaagttcctc 15121 ttcttcacct gtctttagct tcgccttttt tatttcatca atctgatact tgagaatatc 15181 tattttacgc tccctttcat ttttgtcacc ggtcagttcc ttcaacctgc ttttaatctt 15241 ccggtatgtt tcaagatgtt ttaaatactc atctttcaag ctttgaagcc tggaagacgc 15301 aaaagaatcc agaagatcga tgtggctttc ggttcttaag agggattggt tgtcatgctg 15361 tccatgtaca tcaataagcc tttctcccaa ttgttttagc attgacaccg ttgcaattct 15421 gccgttaatc ctgcaagtat tcttccctga agtggtaaac tctctggaca caaccaaagt 15481 accgtcttct tcccagtcta ttccaaaatc ctccagcaaa tcttccaccc tttttttatc 15541 cacctgaaag acggcttcaa caatggcttt gtccctgccc gttcttataa ggtctttata 15601 cagtctttgc cctaaaatgg catttattga gtcaattatg atggactttc ccgctccggt 15661 ttcgccggtc agtacattga gcccatctcc caactcaatt tcaaccttgt caattattgc 15721 tacattctga atttccaacc gttggagcat gcccaaccct catttcctta aggattaaaa 15781 attttgaaaa gaaattggaa ctgtgtcatt tgtcatcgga ttttgcaagt ttacttaact 15841 tttcaacaaa ttccttggca atcttttcgc ttctgcaaac aatgagtaca gtatcatcgc 15901 cggctatcga gcccactatc tcgggatagt tcatggaatc aattgccgat gccgctgccg 15961 gtgccatacc cggaagggtc tttaccacca cgatattgtt tgcataatca cttgaaacat 16021 aggattttga aaataccgtc ataagcctgt tgaatacggt attgtcagta ctattgaaag 16081 gtgcgtactt atatcttccg tcctctgtca ttacttttat gagtcttaac tcttttatat 16141 cccttgatat tgtagcctgg gtaacttcca taccggcttt tttcagtctg tcagcaatct 16201 cttcctgggt ctcgataact tctttgtcga taatctccag tatctttgcc tgcctggcgt 16261 gcttcatatt acttcatgct ctctcctctg tcataaattt tacctcttaa cacatcgaaa 16321 aagttttttc cattcagcct gaccataggc atccttatcc gggacttttt tgttatgatc 16381 acatccccgc ctcttacctc atagccattc tgcccgtcta cggtaaccat agcttcatgg 16441 ctgctgcttt cggccaccac cacttttatc accctgtcgg ccgtagttat aaaagatctt 16501 gaatacaaaa ggtgcgggca tatgggggta cagataatca aatccacatc cggctccacc 16561 aaaggtcctc ccgccgaaag agaataggcc gtagaacccg tcggtgtcga gataatcagc 16621 ccgtctcccg gataaagatc cataaaggca tcgttaatat atgttttaag atgcaaaatc 16681 ctggatattg ctccccggga aataacaaca tcatttaaga caatatcctc tgcaattatt 16741 ttgccgtccc ttacaataac ggtatcaagc atcattcttt cgtcgacggt aaatttatcc 16801 tcaaccagcc gctttaccgc attttcaata tcgttcttgt cgacatccgc caaaaaaccc 16861 agcttcccaa gattaacacc caaaagcggc ttgcctttta ccacagtcat tctggctgcc 16921 ttaagaaagg taccgtcacc cccaagacat accatgacat cggacatatc cactatgttg 16981 tcctcattga tatttgattc tttatctccg agctttaatg caatatcatc gcatacaata 17041 gccgttccgc cgcatttttt tatgctgtct acaagaatcc tggtatattt aagttcttcg 17101 tccttgtctt cattaggtat tattccgatt ttcaacatta tatccctctt tgctctgaaa 17161 aagtaagcca acccaacatt ctaatatttt gtattatggt cgtctccaaa taatcccata 17221 catttaatat gaaattaaac aagatctttt cgcaataatt atataaaata aatttcaaaa 17281 gcacaacatt taacaatctt ttaatcatat taattataat tatttcttta gtttttttcg 17341 atatttaata ataagcggta caatgctgtt taagctgtac atggcttaat tttccgtatt 17401 ttaattgtat attcatcgga gttttatacc tgtgtattca gtatacattt ttcatgaaca 17461 ttgtatgatt ttcaggagtt gataacaaat atgaacatca ttaacaacag atacaaggta 17521 attacaacta tcaaggaaga cttgtcaaac acattatacc ttgtttcaga tatgataaat 17581 gacaacaaaa aaatggcttt taaaatcatc aatccggaac ttatatctcc aaaaaactta 17641 gaacagctaa agaaggaatt tgtaactctt tcttcactgt cccatcccaa tcttatgcaa 17701 atttacgggt ttggaacaat aaattccatt gacgggagcc tgacttcatc caaacaattt 17761 tattgcacct atgaatatat aaaaggtaaa aatataatca gcgccgtctc aggcacgagt 17821 tttgaaaaga aaattgacat tattctccaa atatgcaatg cactttatta tttgcacaga 17881 agaggatttt tcctcaaaaa tcttgaccat aaaagtgttg ttgtaaccga aacagacggc 17941 aatctttgcg taaaactgat tggaatgccg ggaaatgaag aaatggaaaa agtagttttt 18001 cgtttaaaga aaatatccaa tcagtttaaa tttccggaag atttaaaatc ctcaaataat 18061 aacagcaatc ttgctgatct ctattcactg ggcgttttaa tcttctatat tctgacgggt 18121 aaaaatccta acagatgtaa tttcttgaat atttgggaac aatgcaaaaa caatccttcc 18181 gtcttaaaat cggtaccgga caacatagac aaaaaaaggt tgctgggaat tatttctaaa 18241 cttacattaa caaatcctga aaatcattac aagagtgcat actctgtaat taaagatatt 18301 gaaaaagtat gcggtataaa agaaacccgt tttcagaaaa aatggtttga aaaaattata 18361 accaaaacca agctgatagg aagagaagaa aacataaacc gtttgaattc atggataaac 18421 gatatttcaa acaataactg cagtcaaaaa ataacttgta taaccggtga agccggtatt 18481 ggaaaaacaa ggcttttagg tgaacttatg ttctcgctga gtcttgaaaa aacaagggta 18541 ttgcatgggg tgtcctctga aaacgcggaa aacacttatg aaccgataaa acaaatactg 18601 gagcagttaa tcccttatgc accggccgaa atattggaaa gtttcaaatc cgagctggta 18661 aaaattttgc ccgacgaaaa aagtttaaaa ggagcggttc cgagtccggc tctgcctgat 18721 gaaaaggaaa aactaaggct taaggtgaga gttggaaatt tcatagccaa tgttttggag 18781 aaagaactgt ctgttttgat atttgacaat gctcaatggc tggatgaagc atctttagag 18841 cttatcgact atcttgccgg ctcaaaaaag attcctcttt gcataattct gtcctaccgg 18901 aaagagtcca tgaacaaaaa caagtcagga caaaaataca tcgaaaaatg gctgagctca 18961 tccattgcca acgagataac cttaagtcgt tttgactttg aagaaacttg tgaatttata 19021 aaaaatgttc ttgcaataac aacctcccct gccgctttct gtacggaaat gttccgttac 19081 accgaaggaa acccggggtt tataatagac gctattacgg cattgttcaa ggaaggaaag 19141 ctgtacattg atgacagcgg gcagtggagc actgattttg atgaagatgc ggactattcc 19201 aggctctata tacccccaag catgcacgaa gctgtgtgga agcatatcaa tactttggat 19261 aagatttcgt atgaaacttt ggaaacaatt tctgctttta acatgcctgt ctctcttgag 19321 ataatcgagt caatattgga agcctctcat aatgagataa aagacatact ggcagaactt 19381 atttcccacc agataataga acagaggctt gccgactggg gttacactta tgattatcac 19441 tcaaaaaaaa ttaaaaatga aatctacaag aaaattgaac cttccagaaa aaaagcactt 19501 cacaaaaagt gcgccaaaat tttggaggaa atgtataaag acgacaacag aataaacaag 19561 gatgagctta tttatcacta tataaaaacc ggcgaaaagc aaaaggcact gaacatcatt 19621 atagaatccg ccgacagaat gttaaagctc cacatcaatg cccagaccat ggtttatctc 19681 aaaagaggac gtcagatagc aaaagaaatt tcttctgtaa aagataccat aaaaatcctt 19741 ttaatgatgg gtgaactcta ccgcaaaaaa ggagaaaacc gtaaagcctt tgaatgctac 19801 aatgaagctt tgaaatatgc cagggaactt aatgacaaag caacaattgc gaaagtcaag 19861 gaaatgatcg gagccctgta cacaagaaaa aatgattttg accgggcact gcttttcctc 19921 aatgactctt tgtcactgtc caaagaaata ggatatgtgg aaggctatct tgaagccgtc 19981 cgccgtatat gctgggtata tatattcaaa ggaaaaaaca aagaagcaat agacatgatt 20041 aacaatgttc tttcagagta cagtaatgaa aaatactccc tctatcatgc ctcgctttac 20101 aacgttcttg gtacccacta tctggagcag tcaaatatag acgaggcttt gagatgctac 20161 aataaaagta tagagcttta tgaaaaaaac aatgaaaaag ttgaaatagc ttatccctta 20221 aacaatattg ccactgtatt tgccgaattc ttaaatgata atgccaaagc ccgggaatat 20281 tttgaaaaat cccttcagat aaaccttgca aacaacatgg ttgaagggat atccagctgt 20341 tacgacaacc tcggcgaaac ctaccggctg gaagacaatt acacccaggc tctggaatat 20401 tattttaagt gtgaagagca ggcaagggaa tgcgagctca attccctttt gttcacggta 20461 tataaaaata tcatgcttgc ttatctggaa ctttgcgaat accaaaaatc ctatgaatat 20521 ctgcaaaaag taaaacagga aatggaaaaa aattcagacc gcgggcatga cgttcagatt 20581 ttctatgaat atgcagcaaa atattacttt gaaatagggt gttttgaaga agcaaaaaac 20641 atggctcaaa aaggaataaa cacatgcaaa aagttatcca ccagtgaaag cctgacttta 20701 aattgcatta tacttctttc ggaatactat gtctcaaacc aaaaagattc agagcttctt 20761 ttcgaggatg ctcttactct gctgaaaagg cataaacaaa gctcaactgt aaaagaacaa 20821 agagacatga ttcatttgct tgccgaagca cttattgctt ccggcaacac ggaagcttcc 20881 ctaagccttt tggaaaaaag cctggagctt agcgcaaccg taaatacaaa aaagctggaa 20941 atagaatacc ttatacttta cggtgccagc ataggcggga actgcggaat agaaaccatt 21001 aacagcggac taaagttaaa cgctgagtac aaaagcctac gtttaaaatg gaaaggctat 21061 aaaacaattg gcgatattta ttattccatg aaggaaaaaa gtttggccgg cataaactat 21121 ataaaggcct tggacgcact gtatcatctt gtacaaaaag ttcctgttga atttcacggt 21181 tgctttttgt attctcacaa ccgcgaggag tccaggttca ggctcctttc actcaaggct 21241 gacgagctga aagaacaaga attgtcaatc gaaaagcaca taaacaataa aatcaacagt 21301 ggtaaaaaca tcgtccaaca tttctttgaa ggaataaatc atgaattcgt actcaaaggg 21361 gccgaaagcg ctatggcgtt ggacagcgct caaagccatg cttcaaaagc aatcgaagaa 21421 aagcttggga tgatagaaag cttgtttatg aagtttacgc cggattattt aagcaacctc 21481 aagatgatcc ttgaaaccgc atgcgacctg acatcggcag agacaggata tatactgcgt 21541 tacaacgata aaaacgaact ggatgccttt gttgcttatg atagcaacac tgaagccaat 21601 tattacagtt acataatcga acgtaccaat gaaaatattg aaggaatatt tgcagctcaa 21661 agttttgaca aaaaagcagg aaatattgat attttccttc ccggaaacat caaagccgtt 21721 atatgtattc ccatatacag ccatgaatcc ggggacagat attcgtctgt aaaaccgtca 21781 aaaagaaaac gccgggaatc aaacgattac aatattaaag gatatattta tctttcaacc 21841 aaaaacgtat tcaacagatt ctcatggcaa accttcggca tggttaagct tctttcaaaa 21901 attgcggcac tgcaaataga aaattacgac cttaaaataa tttcaaccac cgacaaattg 21961 accggaacat atacaagaaa attcttcgaa aatgccattg aaacacaact taaaaaggca 22021 agcagggaaa aaagccagat gtcaataatt atgattgata tcgacaagtt taagagcata 22081 aatgacaact atggtcatca aaagggagac gagattctct caaaagtcgg aaatattctg 22141 cttaagaata tcagaccgac agatatttgc tgcagatacg gaggcgagga atttgtaata 22201 atacttccgg atacaggacc ctccgaggcc gaagccctgg ctgaaaggct tagaagcacg 22261 gtggaaaaag cccgcttgat gggacaagga aacagtctta ccataagtct tggtatatcc 22321 tgctatccga aacacggcag catacgcaat gaactcattg aaaaagccga ccaggccctt 22381 tatcatgcaa aagaatcggg ccgaaaccgt tactctctct ggaatacaaa aatgaaaaag 22441 ctgtctaaaa gaatggacaa acttgccggc attatatccg gcaatgtaac ccacgatcaa 22501 agaaatgttc tggcattgct ggaaatcgtc agactctcca acgaaacaat gctttttgat 22561 gataaaatat accgagtgct tggaacaata atagacactt tcgatgcgga atacggagtt 22621 ttaattgtct gccaggagca aaatccaaaa actttaaagg tctatgcaag aaaaagtaca 22681 gtaccgggat gggttgagga agaatgctac aacaaaaaaa tcgtagacaa agtactgaaa 22741 caaaaagcag gagcttacat ggtggactgg gacaatgcca acgtaattga tttgcaaacc 22801 ggcgaaaccg tactcaattc aatattggtt gaacccatat taagaggaaa ggaagtaaaa 22861 ggcgtcctct acctctcccg ccccatcaac cggaaagaat acggctttaa tgaattgaac 22921 ttcctcagtg ctttgggaaa cgttatatcc ggtatattat caatgccgta aactttcaaa 22981 cattccagcc tcttttgctt caccccaaag aagaggctga attataacca ccgactcagc 23041 cggtggtttg ctctaaccct atacgggcat ggttcttgca gcgttttaag acacattgaa 23101 tggttcgcca accgcatatt cttctcaagc caccactaaa gtggttttat cttttgcttt 23161 ggtttgcttc tattatttct actcctttca tttcgcccgg ctttcttaat atttatccca 23221 tgtatttcct tatatttccg tatactactt atttcctata ttttggtgca aataccatat 23281 ggtatttaca attcccttgc gtatgtgcta aactatataa tccttacctg gcttcagcta 23341 ttattccgta aaaaattagt atataaaggt acaaagcctc tttattttca ctgggttcct 23401 cataatccaa ccttcatatt ataaattatg acttaagtat acattatctc ataagatact 23461 tacgctgttc tattaagaaa gctgatacaa catacaacac cagccctgtt agccaatggg 23521 ccacggcata tttcagcgag gactcaaaag gcttcggatt aatccattgg catgtatgcc 23581 aaagccaact ggcccctcct ctgtaaaaaa agcttatggc aacccacaaa atcggaatgc 23641 cgtaaccaat tataagttgt ctgctcacta aaaaagccgt cattccgaaa cctgacacaa 23701 aaaagagggc tcctgcaatt aaaaatatat caacaatgcc atactcaagt ctgtcaccat 23761 cacttataga atatataaaa tacagtagca gcaatacaaa accggtatat attgcaaaca 23821 gtctcaacat tctcagaaaa ccgtatttaa acccgtctat gggaagtgac aatatcaatt 23881 ctttgctttc cggttgtaca atttccatat aaggggttag tatccaggcc aatacaccaa 23941 ctaccgatac tacaaacaca gtcgtctgaa gcaaaatata ttttgtcgcc gctcctccca 24001 taagcacaag gaagaatatc ataactgccg caaaggcaag cagtataaaa tacccaacat 24061 aacttaccgt tttcaaatca aaaatcaaag gtaccatctt atttacgcgt ttatccatgt 24121 caaataacct tcctccaccg ttggttgaac cgcctccgca tcttccgacg gtttttcttc 24181 ggaataaacc cgaatttcca aattattatc cgcattggtg tttgttgaaa gtatcttgta 24241 cttgccctct attttataaa aatcattact gtttataacc attttccata ctttcccttt 24301 tgccatgttt tccaattctt caaaaccgtc aaactgctta accttgccgt tatttattaa 24361 tgccagtcca tcgcaattgt ttttaatgtc ttcaataata tgagtggaca gcaatacaac 24421 cctgtttgcg gcaactcttc ttataaatcc tctgaacctt atacgctcct cagggtccag 24481 accagctgta ggttcatcaa ccataataaa tgcaggattg cccagcatag cctgtgcaat 24541 tcccagcctt cttctcattc ctcccgacag ggctccgact tttttctttg cctcattact 24601 caaattaacc tcagcaagaa cctgttctat ttgctttttc cgctccggag cccttattcc 24661 ctttaaaaca cctatcgtat ccaggcactc ttcaaccgtt atactcttgt agcacccgaa 24721 ttcctgaggt aaatagccta tcttgtagcg aaatttgtcc atatttttca gcacatcttc 24781 cccgtcaaat tcaattctcc cttcatccgg cgctataagc ccggcaagaa tcctcatcag 24841 agttgtcttt ccggcaccgt tgggtcccaa aagaccgtag attccgtttg aaataaacaa 24901 gttgacagaa tcaagagctt ttttcttttt gtagcttttt gacaggccct ctattttcaa 24961 tctcatgcct tatacttcct ttctatttca aaataaaact tacagtttac tttgacttat 25021 ttactgttat ccattttctc agtatttcat atgctatttt gcttacttca tccttggatt 25081 ctgcttttac gagtctttca atttcataga tatcattgag gtcgttttcc catactattt 25141 gcttttcctt gccttcgccc caccattctg tatagtattc ctccagatct tttttttcac 25201 cggtttcagc tatttcaatt aagcttggaa ataaacatgg cgcaacactg ctttccatat 25261 atttgcccgt cctccagaaa cactctaaaa taaacattgg ccttaaaaat tcacaacttc 25321 ttcttatacc atcttcagaa gcaggatata gccacgaact gtaatctaaa tataattcat 25381 tttgattaac taggattgat ccattcattg atccattcaa attaactaaa aatactttat 25441 tatatttatc acagaggtta taatcagcct caatccccac cgaatcttca aattcctttc 25501 tatatttcat aagcaagtca ggtactatgc ttatatattc cttataagaa taatatattg 25561 aaggtggagc aacaaaatgt atccctccga tattcccgct ctcgtaatct ccctgtataa 25621 ctgcaggccc ggttgcctgg cctttaaatt ccgtacctat atcgcaggat aaattggtta 25681 ttacatttcc cctgtggctt tttaatacaa tatcataggg ttttccattt gacaaattat 25741 tagtcaagta atcataagta agtaccggaa gtattacttt atgttttccc aatataggat 25801 accagggaaa atccggcctc aataacaatg tacgatccgt tacttctcca agtgcatagg 25861 gtagccgtcc ggaaacatta atttcaattt ccgcttctcc ctccggagga tcttgtataa 25921 taatccaatc cctatcccgt acaaactcat tatactcagt tccgttaatc ttcacatctt 25981 taatagcaag gcttctgtat aaagtaaata ttattggttc atttttaata ttatcaatgt 26041 taattttagc ataatattcc agcaaatctc ctttgctatc tcctaactcc aaatgaaaca 26101 attttattcg accgttacaa tatttctctt caaatctctc cttagcctgt tcgagtattt 26161 tatcattcca aataccaaaa tcaaggtacc tcattttccc ctgagagtga tatttggttg 26221 aaaacgctgc caacggtatc gcaccgataa ataacaatat cgccgctgtc cccgctattt 26281 tagccttggt atttcttaaa ttccttcttt ccaacctgga caaattagca aaaatatata 26341 cggacatgcc aaacattaaa aaccataatt ttcttgataa caatccaatg ttcatttcaa 26401 gtccgtaatg taaaagatgt ggattgccat ggggttcttc aacaaattga tttaacatta 26461 aagatatccc actcgatcca ttttttattg gtgaaataac ataccatatt aacagcaaaa 26521 taggccatcc cagtttcggg ttaaatgttt tctccactga atatgcaata agccaggtgg 26581 ataccatggg catataaaaa tttacgaata tgtagggtgc aacttgcaaa gcatacttac 26641 ccaattcgtt taatccatta tcaacccaaa cagtacagaa tatagcaagt accaaacaat 26701 aaacaaaaga gcagactgac cacgtaaaaa cctttgccat ctggcgtatc caagcagacg 26761 gtaatgtatc taacacttcc tcaaatttgg catctttatc ttgtctcgca tttataacac 26821 caaaacacat tgataaaatt gtcaaaacca tcataacaaa accactagtt cttataaatg 26881 agaaattatc aagtctatct ttcataatac aatacccata aaacatgtat aaaaaagata 26941 aaaacatggg aattattaaa taatattttc tgataaataa ttttgtttca agtgtaagta 27001 ttttttttaa aaccatcata ttgcacctca caagcaggca taagacccag accattggtc 27061 caggtcttat gccaaatcat tatgtatagt ttataactga taaacttcga actctgcttg 27121 acccttagct gactgagatc cttctattct tgcataatac ccaacattaa ctgtttttaa 27181 gtcaaaataa ggtgtccagc ttgtccaaga agtctggttg gtaactattg tcttaagttc 27241 ttcatcaaac caattctctc ttaccctcat tgcctttgct gtaacttgta acccattctc 27301 agatctagct ctcaatcttc cttgtcctga tgtaccccac aatgcaacta aactacctgt 27361 atttgatgtt tgggtatcac ttaatgtaac acgtgatact ccaataaatg ttaatgcatc 27421 aacagcaaca ctagtaacaa taatacaagc taatattaag ggaaagattt ttctgaaaat 27481 ctttttcatt gcttttctcc tccttttatt ttaagttttt atagcattaa ttttcttata 27541 ccagcagctg atataagatg atagattgac taataagtag agcatgtcct actattttct 27601 attataatta tatatatata tgtaactata atgtcaatat ttttaaattt atgaatatta 27661 aaattgtttt tatcatttac ttttattatt tactttttat gtttactatt tcttttttat 27721 ggttttgctt gttccaccag ctttttgtat ataaaaaatt ataaataaaa ctccaacata 27781 atattgtaac ttatcattaa tcactatact aatgataagg agtcacaata tatgatggag 27841 cttgataaaa tttattctgt taaagatttt ctcaaatctt taattttaaa atgattaata 27901 attagtggaa tattaatgga ataaataaat tgattacctt tttgattatt tttcgtcatg 27961 gtgtcactat tctcatatcc cctcccggga attcagtaat tacttttaat atatattttt 28021 tcagccatga ataatcagtg gaatttatat ttccgtttcc gtcaatgtca gctgctgcta 28081 gctttaaatt atcatcaaga attacaagtt tcaatatatg tctgttcaac atacccaagt 28141 ccgtcgaatt aattttgccg tctctgttta tatctcccac cagaatttca acccccggag 28201 gagtcggttc cgcaattcca ccctttggat aaacccccaa ctcaaatatg gagtttccgt 28261 actgagttgc cctttgcata caatagattc ttacatatct tcctcttgcc tcaaggtaaa 28321 tatcgtctat atccccgtct ccgttgtact cggtgtatac atcagtccat gtgacggcat 28381 cattggacac ctggatttta tactgacggg cgtatgcagc ctcccactca atatacactc 28441 tttcaatttc atattcatcc agaaggtcaa catatatgta ctgattatcg ctgtaatccg 28501 atgaccatct ggttgctata tttccgtcaa cagccttctc cggtgtgtta cccagccctg 28561 gttccgtcga agatgcatat acaggcttgt tctgcgcaat acttccggcg ggaatgttta 28621 ttaccggagg ctccgttgta ggctcttcaa gcattgaagc cggacgaacc gcaatattca 28681 ttatgctgta aggatccgtt acgcaaactt ccaatcccca tcctctcaat gtatcaaaag 28741 ttccgtcggt ggtcatatcc aggaaagtct gcggctggtt gcccggtccc catgaccatg 28801 ccaggtaacc tacttcattc ttgtagcatt gctccattat ggttttgtaa gggattttac 28861 ccatttcatg ttcttcccat tggtgtccga attctcccac cacaaggggc aagcccattt 28921 caacagattc ttttatttca tcgattactt tctgttcatt gtaaccccac atgtacggcc 28981 accacatatg taccgagaac aagaggtttt tgtcagggtc ggcgtttata agataaggtc 29041 cggttgcctg aagaatatca atattctttc cccagtcgct gccgtcaatc ataagaggaa 29101 catgaattcc agcttccctc attctcttta cggcagcctc ataccctgtt ttaaattcag 29161 attccgaaac ctgggctcct acttcattac caatattgat aatgagatat tcctgatgtt 29221 ttttcaatac ttcaagcaca tcgggtcttg tccaatagtc aacgagcatg gaaagcttct 29281 gccattcacc ggttgcgtca tgaagctcta taataggaat catattgttt atacggcaat 29341 tgtaaagcaa aatatcaagt ttccttgccg gcccggaaac tgaccataca agtcttaccg 29401 cattagctcc ggttttcctg atttcaggaa gtgccacatc accgtcaatg tcgccccaga 29461 tcgacatttc gttcacacca tacagtatta ttttttcacc gtatttgtcg tacaaaaacc 29521 tcccctgaac tctaagtccc ggataaatgt catccgcccc cagtgttaca aacggcaggc 29581 tgacagtcat taaaatgaca acagccaaaa gaatgcacac cctctttttc attatcattc 29641 ctcccctttt taaattcatt taattattta attcctccgc cctttaaatc ggaggacttg 29701 tgtcggtttt aattttgaaa aaagtaatat tacttttgca agatgtatgc cggatatgct 29761 caagttttat ccatgaaaag ttgctttgta gtaaatatga ccttatttga agaaaatctt 29821 caaattccgc tttattgaaa acattatatc aaatataatt ctaaaataca tattaccaca 29881 tatttctttt aaatgaaaga gaaaataatt tagtttgtaa cattattttt ctgttttgta 29941 attaagactg tacaaaattt ttatttccct ttatttaatg aaaatttgac tttacaaaga 30001 tactttacaa aaaatatata tacctttaat ttaaaaaaaa taaaaatata caccgccctg 30061 tataaatttt gctttattta tagtataatt tgcttagtgg cctgtttcca aaagctgctg 30121 aaatctcagg tttgacaata gacaaacatt ccacccgaaa ggagctgatt gtatggcaaa 30181 aaagctgtta ttcatggcgc tgtgcatcct tgttttttac tttccgttga tttcccatgc 30241 cagtgcaaac atcacggttg tggtaaacgg cgaaaaagtt aactttactg accaacaacc 30301 tttcattgac agcaactcaa gaacaatggt acccataaga ttcatttccg aagccctcga 30361 cgccaaagtg gattggattg aaaaagagcg catggtggta ataaaaaagc agggaacgga 30421 aatttcactg gttgtaggta tgaaaaccgc caaagtcaat ggtaaagaaa tcaagcttga 30481 tacttcatcg gttattgcag gaggcaggac ttttgtccct gtaagattta tctcagaagc 30541 ctttggtgct accgtagaat gggacggtaa aaacaaaatt gtcacaatca caaccaagcc 30601 gcaagccgga aatgaaatcg gtaaaatgcc cgaatcaagc tattacaacg aactttacaa 30661 cctcttcacc ctcgtgccca aaggtatgaa aggctccaat atagagcagt tcgcttatta 30721 cacctttaaa gaagatggta ctgtcctcaa cctcaacttt accgaagagg aaatattcaa 30781 aggtcattca ttccccgagt tgtcaaaagg cggggttatc ttttccccca gcaaccttga 30841 aaccgttgaa tcatacactg ttgaaatctt caaaaatgtg tcaaggacaa acaaacagct 30901 tgtcggtcaa tacatatatt tttccgattt aaaacctgaa aaccttatgg ttattgaaaa 30961 aaacgggttt acttttgtca ccacaaaggg atttaaacct tttgaaatca aagaaaccgg 31021 ctacaagctg atgagtaaaa aactctttat atacaacgac aaaaacctgt atgttttttc 31081 atttatttat gacccctcgg acataaagta tcttacggaa agtgttatgg acagcatcat 31141 taattccatt gaaataaacg gtaccaaaat caatctgaaa aaatcaacaa caccgggcaa 31201 aaacggcgaa gttgaagata ttttaccggc agaagccaat tataccagga aaatgactgt 31261 aaaagaaaat gaggaacggc ttaaaaagaa atatttttct caaggatttg acctttcgga 31321 catggtcaga attgaaggag gcacctttat cgacgaaaac ggtgaaaaag taaccgtaaa 31381 gcccttctac gtcagcaaaa acttagtgac aatcagcgaa tggaacagca tctcaaaaaa 31441 taaaatcaac atcaaagacc tcaacgcaaa atacaattta aacataaaat ccgaaaatta 31501 tccggccgta tttgaaaccg aagaaaaata cggcacggtc aaaataaaga acaatatgga 31561 gctttacgtg ttctgcaatg aaaaaagcaa aagtttcgga atcgaagaat attatacctt 31621 ccaaaaaacc agttacggta cttctaccat ctttgaacac aacggaggat tcaggttgct 31681 gagtgaagat gaactaaaat acatattgag aaaaaccaaa tccgatgcct ataaaaacaa 31741 cgtaaaatca aataccgttt ccgaagtcgg acgttcttcc aaaaacgagt ttggaatttt 31801 tgactacgac tctaatgttg cggaagtaac ggattttgat tcggtactca aaatcaaaga 31861 caattctcaa atgctgtgcg gtttcagata tgcaaaagat attggaaatt caccacaaga 31921 tttgatactg gattttttca gtaattaata tttacgtctg ctattttcgt ctgcgccgga 31981 attgataaaa acagccctgc ggcagttttt gccacagggc tcttttaccg attaaacact 32041 tatatattag tgtttatcaa tatttatcag aatttatatt ggtaatttct cgattaccct 32101 tatcaaatat cttgaaagta ttgtgacatc actggaatta actcttccgt cacgatttac 32161 atctgcgttc ttttcagctt tggaagaagg cagagttgag acggctttaa gaacatatct 32221 ttttaacaaa gtcaagtcag tggagtttac ttttccgtca tcattcacat ctccgtacag 32281 tacttcattt tgagcagaat tatagttgac aaatccggca agggcataaa tcaatgccgc 32341 attccagttt atagcaattt cattggtctg ataactgtcc tgaatatcca cccaatcctt 32401 cggtccgggc catcctcctc ctacaaggta accgggccac ggctcccata ttccgtcagc 32461 ccctgaacgt ctgtcatgag gattcatagg aggatttata ccaaggcctg ttacataaga 32521 cctgttgtaa tagtttcttc caaatacatg tgaaatcgca tcgagagcag catttacata 32581 atcattgttg ggtgaaatct tgttcgcaac ctgaagtatc atagtctgtc ttacaaccgt 32641 gccgttgcat ccccagtaat atgttgtacc aagggttctg ccatagccat ggttttggct 32701 ggtcctcaca attgaatccg cagtggaaag gagactatcc tttattgact gcaccaaagc 32761 aggattcttg cccggtcttt ctgacaaaag atatgtaaac atacctaagt ttgcaacatt 32821 atcccagtca aaatcggctt ctattttttt cgagaattgc gccgccctgt tttcaaaatc 32881 tctaaggtat tcttcatctc ccagggtctc ccacatttca gccgccgccc acaatctgtc 32941 atctgcatca ctgacagtgg catattctcc tgttgagaat ccactctggt ttgcaaaaac 33001 attcgcagga ttgttcttca aaaactcata gcttactttt gccgcattta tacatttttc 33061 agcatattga ggatcataag gcctgaatat tcttgcagcc atggccgtca tggcaacaaa 33121 gtctgccgtt gcggcactgc tccagggcac gaaaaatctt tcgtcgtgtt cgttctcagg 33181 catgataaag ccgccaaagt tccttgtcga aactttatga gccacccttc cgctcccgtc 33241 agggtattgc atggtaagaa tccagtctat ctcatatttt aattcatcaa gaaaatccgg 33301 tattgaattg ttcttttcgg gaatctccaa tgccacaggc tccaactggt ctttaaaatg 33361 ctcccacgcc aggaacattg aaccaacggt tatgccggcg tttaccacat atttgttgta 33421 gtcgcccgca tcatgccagc cttttgtact gtctttttta gtatgctgtc cgtttatata 33481 atcaagatat gcatcattag tatggcacgg tccatgggaa tagtgtattc cgttgtatgt 33541 ggccgacaca ctggtgccgc agcgcagcaa atacattccc agcattgctg ttttaaaagc 33601 atcctcatat acattcattg caattttaaa gtttacgctt tttcctactc ccggcacggc 33661 aagatagtac gttccttctt cattaacgga tgaaaaatca gcaatataaa cagtttcttt 33721 tgtatcattg tcaaacattg aagttgccgt tccggtatac actattgttc cgtcttcttt 33781 aacaacataa aaggttgaac aatttgcagc tatagtcgcc tttttgctgt ggttcggtat 33841 aaaacctatt gagtttaaac ggattcgtga atcaaattga taattctccg ttatttttgc 33901 agctgacact ttggtctcaa tcaatcccga aggaaacact ccggtcaagc ttagaaacac 33961 tacagcaatg accaaagata aaatacgttt tttcatgctg cttttcaagg tcattctact 34021 cattttttac ctttatcccc ctttttatta aaaattgtaa aatacctgaa ttaagataat 34081 ttaaaacctg ttgcaacctc ctttcttcca caagtttaat tattatttgc ttcaggtatt 34141 ataaatgcag gtataaatac aggcattttg aatacagacg tatgctggaa ctgagctaaa 34201 gcattggata ggagttttag tttgaaacaa gaactcatca attgcttctt acattctaaa 34261 aagctaacaa aaaagacaaa aaaataaatt atatggataa atccaattgc ttaagtgaat 34321 ttaattatac catctaaata gcaaataatt caatattcaa tacaatatat tgcaattaca 34381 attattatta catatgttta ttattgtttg tttattatta ctgtgttttt tatcgctcaa 34441 aattgcaaaa cacttccgtt tggctgtttt tgggctattt ttctttagac atcaccgctt 34501 cttttcccat ctcaaaaagc gtcttggcat ccatttcttc aacttcagat atcaactggg 34561 ccgcaatacc taccggattg tcgaaatcgg gaataggaaa atcactgtca aaaaattcaa 34621 aaagttcata ttcaagttct tcgaagtcca tgtcgcttaa gacataatcc tgctcgatgc 34681 cgaaaaattt aagaaattct tcccggcggt tgttatatac gtcgatcaac agctgtttta 34741 gcgttttgtg caaatagtta atggcaattg aatctaaatg tgaagtgtca ttgtccgggt 34801 caatctcaag ataatcatca gtgttttccg tcacaagccc ataatcacac aaaaaatccc 34861 ccagtttctc atagtcgtca aggttgtatt tgccgcaatc ctttatttga ccgctgcttt 34921 cgtcgtattc atacttgttt tcatacagta ttgaaaaagc aaaactttca gctatatcgc 34981 ggacaagctc atccatattc tctttaacag cctttttaaa ttcataataa agccattcat 35041 agtttagagc agatttcagc ttgttctcaa tcatctcaaa atctttttct tcgagcaaat 35101 cccgaagttc ttcgtcgttt aaataggttc tgattatgaa ttttgggttt ttttcaataa 35161 gttttaatat cacgtctctt aattcatagc tctcaatagt atggtcaagt attttttctc 35221 tgatttgttt cggaaattgt ttcagcaatc cctttttcat tgagcttcaa gcctccagca 35281 tctgataaag tcttaatttg aataaaattt ttttacgggg acagttctgt gtgtgaatca 35341 tcaataactt tattcaccag ctcaaaaagt tctccttcgc ttgtactgcc ctcttttttt 35401 gacaaataaa caaggtattc gatgttgcct tccgggccct taataggtga aaaatcaagc 35461 cctcgaattt taagtccttc ttttaagcta aatgtaataa tatcttttac tacttcctca 35521 tggacctttt tgtcccggac aaccccatgt tttccgacct tttcccggcc cgcttcaaac 35581 tggggcttga taaggcataa aagctcaccg tcgtccttca gcaggttgat tacaacagga 35641 ataacctttt tcagcgatat aaaagaaaca tctatcgacg aaaagtccgc aagaatacca 35701 atatcttccg gttttacata tcttatattg gttctttcca tgcaaacaac ccgttcatca 35761 ttcctaagct cccatgccag ctgtccgtag cccacgtcaa ctgcaaaaac ctttttggcc 35821 ccgtttttca gcatgcaatc ggtaaaaccg cctgttgatg ctccaacatc gatagctgtc 35881 ttatctttta aatcaatatt aaaaaccctt atcgcttttt cgagtttaag tccaccccgg 35941 ctgacataag gatggacatt ttcctttatt gtaataatag aatcaacatc cactttgaca 36001 ccgggtttgt cttccttttt gtcgtttaca aacaccaccc cggccattat agagcttttt 36061 gccttttccc tgctttgaaa aaatcctctg tttaccaaaa gaacatccag tctttccttt 36121 ttcaaaaaaa ccttcctccg aacattgaac attattatta aatttattat ttagtgcttc 36181 attcagttta tcttatggct cggaattctt tcactttgct tttatttatc agttttaaaa 36241 catcattgaa aatggaatcc ggatccagtc tgtacatatg caccagttct ttgatagagc 36301 catgaggaat aaaagcatcc ggatatccaa acattcttgt agtgacattt atccccttct 36361 ggtttattgt ttccaaaact ctgcttccaa atccaccctc aacggtatta tcctctattg 36421 ttacaagtct ttttgtttta agtacggaat ttataatggt atttgaatca aggggcttta 36481 taaatctgca ataaatcaca tccgcagaca aacctgtctc cttaagcttt tcggcaacct 36541 tcatggccac ttccaccttg ttgccgacag ccgcaatggt aacatcattt ccttcactta 36601 taagcagaga ttgtcccaac tttatgtcag gggtgtcaaa aagcttttca ggtcctgctc 36661 ctctcgggta ccttatcgct atcggaccgc tatgctccag tacggcatac tcaagcattt 36721 tggcaagctc attataatca cagggagcaa gaatggtcat atttggtata tgtcttaaaa 36781 aagatatgtc ataaattccc tgatgtgtct ccccgtcttc cccgactatt ccggccctgt 36841 ctatcgcaaa aaccacatgc agattttgaa gagccacatc atgcactacc tggtcatagg 36901 ctctctggag aaaagacgaa taaagagcta tgaccggaat catcccgttt tttgcaagcc 36961 cggcaccaaa agttaccgca tgttgctcgg ctatgccaac gtcaaaaaac ctttccggaa 37021 atctctttga aaatttgata agacctgttc catgaggcat tgcagccgta agagcaacaa 37081 ccctttcttc tttttcagca atcctgacaa tttcacttcc aaatacgtcg gaatatcccg 37141 gaactttatt agcaataacc tcccccgtct caacctcaaa gggcgagatg ccgtgaaaaa 37201 cagccggatt tttttccgcg taagtgtaac ctcttccttt ttgggtacat acatgcacca 37261 gtacaggtcc tttggtgttt ttggctcttg taagaacgtt ttccagttcg gcaatattat 37321 gtccgtcaat aggtcctaaa tatttaaaac cgagttcttc aaacactatt cccggcataa 37381 tcatgtattt tatggtgcct ttgaccctgc caagtgcttt gaccgcgctt tttccgattg 37441 ccggtatttt gtttaaaata atgtctatat cttctttaac tttaaaatag aagggttctg 37501 ttcgaatttt gctcaaataa actgaaagcc ctcctacatt tttcgaaatt gacatttcat 37561 tatcatttaa tacaacaata agattattcg gtgaccttcc cgcatcattc aatgcttcaa 37621 aagccattcc tccggtcagg gcaccgtctc cgataacggc aacaaccgaa tatttttctt 37681 ttcttaaatc ccttgctttt gcaataccca gggctgcaga tatggaagta ctgctgtgcc 37741 cggtattgaa agcatcatac tcactttccg ccgattttgg aaaaccggaa agtccgccaa 37801 gctttcttat ggtgtcaaac ctgtcttttc ttccggtgat aatcttatga acatagcatt 37861 gatgacctac atcccatata attttatcct ccggagtgtt aaacaccctg tgaagcgcaa 37921 gggtcaactc tacgactccc aagttggaag caagatgccc gcctgttttt gagacctttt 37981 caataagaaa agacctaatc tcgcctgcga gttgctttaa ctgttccaaa ttcagttttt 38041 ttatatcatc agggaaatta atactgtcca atacagattc caccctggta tcatctctct 38101 ttcaaaccgt atctttttta ttttgtttgt ttttattttt gtttgttttg cggtcgtcac 38161 ttttttgacc gttttgtttg aactttttat ttgtcatctg ccggttttta tgctttcttt 38221 ttttcttttt aatgccaaat ctccctgtca aaaacttagc tataaccccg actttataaa 38281 caatatagtc gcaattttca atggcaatgg ttttaccaat ggcttttccc ccaatggtaa 38341 gagccgcaac aaagcctgca aaactcaatt ccaccaggaa ggcaacaatc ccgccgactg 38401 actgggagac cttgaaaact ataaaagcac ttgcagtacc gcttattact ccgcatatat 38461 ctcccaccac atcattgcaa aaactcgata ccttgtttgc attcctaatg agccttatgg 38521 cctgtttagc accataatat tttcttgagg ccatagcatg aaaaggagat tcatccgccg 38581 atgtcaccgc aattccgatt atatcaaaaa taattcctat aaatacaata acaagcacaa 38641 tcaaaattga aaaaaaaata ttaacatccc caagcaaatt tgatgacaca aacgaaagac 38701 ttgaggacag tacaaaagcc aatattgtta taagtacaat ccatcgtata tttccatttt 38761 tcgaacctaa aatatttatg cgaaacttca tctttttttc atgggaagga tgtttataac 38821 catcatccac ctaatatttt cctcctaaaa acaaaaatat gtaaaaaacc aaacaaagta 38881 atccatttaa acgctataat acagggtggc attatgctga gtaaattttg cggcttaggt 38941 caggcatgat ttccacagaa ggtactgaat gtcgccattt cagcggtttc cctttaaacc 39001 ttcagccgcc cctttaaagg gagcggggcc tgattaccac ttagtccaca cttcaatccc 39061 cagcataact cgcttaacga acagtctagg ggctttcccc gacagtctat ccggttccta 39121 gcctcttttg caagattggt ttcaaactgc tatagtgtat atgtatcggc caatacctat 39181 acacctgacc attatccgcc aacctcactc aaggcaggct actctgtcca caacaccaat 39241 aaatggtatc gcaaaacagg ttctctcccg gctcgtagaa gtgtttacac actgacaaaa 39301 ttattatgct tgcagtgtac tttactccca caaggtcggg tctccacggt aaaggggtca 39361 atgcccgcat gccattgcgg gttgccccta aaccttaact cccagcacca gcccaccact 39421 gggcgtagca agccagcaca aggaacttca tcgatgtgcc ctttaacgga tttttaggcc 39481 cgtcttcaga accggtagta ctgactagaa tactgcacca ccctgtctta caagcatttt 39541 cgcattgatt cgctttctat tcatttgttt ttgcagttaa gttcctatgg cttaaaatta 39601 tatcacacaa aaagaaacgt ttaaagaatg acattctgta aaaaatactc caataaacat 39661 taataaaagc ttttactttg cttctatcta aattatacat caaatatttt acgtatgcta 39721 gcttatgcaa aacacagccc tatcagcatg cccaacatgg cacctacaaa cacctcaaac 39781 ggggagtgcc ctataagctc tttcaaattt tcatcaaaat ttttcctgtc ttcgtctttt 39841 tgagaaaaaa taagtttatt caatactttt gcctgttttc ccgccgctct tctcactcct 39901 gcggcatcat acataacaat tgcggccacc gcagccgata tcccaaactc taccgaatct 39961 aatcccctca tttttccgac cacagttgca agagaaacaa taaatgagga atgagaactc 40021 ggcatgccgc ctgaaccgat aaacctggta aaatccagtt ttctttcaac aacaatgaca 40081 ttaaccacct tcaaaaactg tgctacgaac catgcaatca tgggtacggt aacagtcttg 40141 ttggacaata tgctatatac tattttcacc tacacacccc cgccaaccaa ttaactgatg 40201 atagaatcaa ttttcccttt ccagcaaata tttcgcaaga cttcttaaaa aatccgcttt 40261 ttccccgaac ttttcaaggg catcaacggc ctttttcgtg acatcggaaa gtatttcctt 40321 tgatttttcc aaaccgtaaa cggtaacata tgtggatttg ttattatcgg catcgctgcc 40381 aacctttttg ccaagtttct cactgctgcc ttccacatcc aatatgtcat cctttatctg 40441 aaaggccaga ccaaggtttt cggcaaactc atcaagtttt tgaatatcat ccgcatccgc 40501 tccgcacaat atggccgccg aaaccaccgg cgcctttatc agcgctccgg ttttcagtct 40561 gtgcatacga tttaaaatct cattgtccac ttgctttcct tccgactcaa gatcaataac 40621 ctgtcccgca atcatgccgt tcatccctgc ggctttcgca attactgccg ccgcttttga 40681 ctttctctcc atgtcaccgt tttttattat attctccagc ataatctcaa atgccaggtt 40741 taaaagaccg tcgcctgcaa gtattgccaa cgcttcgcca tataccttgt gatttgtggg 40801 cctgcccctc ctgaaatcgt cattgtccat ggccggaaga tcatcatgta tgagagaata 40861 tgtatgaatc atctcaacgg cgcacgcaaa gggaagcact tgttcaacac ttcctcccag 40921 catatcgcat accgcaaggg aaagaacggg ccgaagcctc tttcctcccg ccatgagact 40981 gtatctcatt gcgctgtaca aagacttttc aggaagctca tttttaacaa tacacctgtc 41041 aagatattca tttactatat ctgcatattt ttccagttgc tgtttaaatt ccacttttat 41101 catcacccat cttgataaaa tcttcctccc ttaccgttcc attttcatct tctatcagga 41161 tagacactct tttttccatt tcatcaagca ttttgctaag atcttttgac agcatcatcc 41221 ctttttgaaa catttcaatg gactcgtcca aaggtagttc ccctttttca agctgcttta 41281 ctatttcctc aagctctttc aatgattctt caaaactttt tttcatccgc ctttacccgc 41341 ctttccgtga cgacaaaatt taatcatcat tcaattcctt cttccttacc gtgcagtaaa 41401 gccttccgtc tttcacactc acttcaattc cttctccgac atccacatcg ttaacggatt 41461 ttacaaaaat ccctttttct tccgacttta taattccgta tccccttgat aatatagtaa 41521 gggggcttaa tgcgtcaagt tttcctatca aaaatccaag ctttgatcct gccctctcta 41581 aagaagcaaa catgctcttt ttcaagtccc tgtttaaaat gtccagcttc attctttcct 41641 gatatattct gtcatatggc tgcctgaaaa ctactgaatc ggcaagtttt ttaagcatat 41701 cccttttttg ctttacattt ctttgaagtg cgtccaccat cctgacatta agctctctta 41761 ttctgtttat aatagttact ttttcaggca ttaccaattc ggcggccgct gatggagtgg 41821 gcgcccttaa atctgcaaca aaatccgcta ttgtatagtc cgtctcatgt cccacggccg 41881 atattaccgg tatggaagaa ttaaatatgc ttcttgccac tatttcctcg ttaaacggcc 41941 ataattcctc caaagagcct ccacctctgg caaggataat gacatccaca ccgccgattt 42001 cattcaattt gcttatcgca tggcttattt ccaaagcggc ggtttcaccc tggaccctga 42061 caggaaatat ctttatatat gaattataga accgtctgtc caaaatattc ataatatctc 42121 tgataaccga accggtggca gaggtaacca ctcctattgt cctcggcata aacggtatct 42181 ttttcttgtg tgccggatca aaaagacctt cgcttgcaag tcttctcttt agctgttcaa 42241 aagcaatata aaggtctcct ataccgtcat tttgcatttc ctcagcatag agctgatatt 42301 gtccgtccct ttcaaatacc gaaatatagc cctttactat caccttcatg ccgttttcag 42361 gcataaattt aaggtgcaag ttgtatgttc tgaacatcac acattttagt gaacagttct 42421 catccttaag ggtaaaatac atatgacccg aagaatgata tttaaaattc gatatttcgc 42481 ctctaaccca aagatttgac aggatcagat cccttgacat gatttccttg atatatctgt 42541 tgactgctga aaccgttaat atgttgtcac aattgtcaga aaaaaactcc cccatctatc 42601 tccaccttga atattatttt taaaattcct ctcacaatct cttattcctc gtctctgttc 42661 tcatttccgt ctgctgacat aagtttcact ttgacaactt tccccaaaat tccgtttata 42721 aaggagccgc tttcttcccc gctgtagttc tttgccagtt cgacagcctc gttgatggcc 42781 acggtgaacg gtatgtcatc cctatggcac atttcatata tggcaagcct taaaattgca 42841 aggtcaacct ttgaaattct ggacagtttc catcctttcg aaaacttttc tatggtgccg 42901 tctatctctt cctgattttt aaaaactcct tttacaacat cgagaatata ttccctgtca 42961 ttttcgttca aatcatattg ttccagggtg ttgtttattt gttcctccct tgagtctttt 43021 tgtatttcaa gctgatatat aagcttcatg gcaatttccc tggatgctct tcttcccatt 43081 taactctttc ctcccaaaaa tcctttacag ttttcttgaa atatatttca taatcatctg 43141 tatgtacccg gcggtaaaat cctgtccagc aaatttttca aataatcctt gtcctgggaa 43201 atcttcttcc caatataata gcctattgca acacatattg taataaatac cgtctggaag 43261 aaacctatta ctaaaataga gacagcgaaa ataaaacccg tgagtgctcc atttatttct 43321 ccgtaatgag atttgtaaaa ttcaatcaat ttctccttgt ttgtcataac caaacctcca 43381 tcactcaact ctggacctgt aaccggtgta ggtgttttcc accgaaactt tcacttcatt 43441 taccacaata ccggtagttt cttcaacaga cttcttaact ttaagctgaa tatcctcaag 43501 aagagcagga atatttatat ccggcattac tattgtcttt ataaatatca aaacattatc 43561 cccctgcttt ttcacataag ccttgttttc tttaacgcct ccaagctttc ttgaagctgc 43621 aagggcaatg ctttctatgg tatttagcga tattcttgtc tctccaagat tattatactt 43681 gctgatatat tttttatcct tgtcactttt tactcctgac aatagaaaca taagacttaa 43741 tccgaaaaag agaagctcga tgataaagag taaaaccgta aaaccccggt cggacaaaac 43801 attcgtcaca agaaacccag acgcgccctc aagcatttca ggccttaatg taaaaatcat 43861 ggttataagg gaaataactg tcaggcaaaa tgcataaaaa gccaataaac ttctgaaaat 43921 aatgttcata tatcaaaaat cacctctttt gttttatctt ctgttaaact tcggcaattc 43981 agattacaca ttttacttta tatgctaatc caaatgcaaa attatatata cattatattt 44041 cattttgcca aaaaaataaa ccctcacggg ttgttaattt aattttttac tatatatatt 44101 tccaaatata tttccaatat accgtcttga cattatctta ccctggcctg ttcctcgtct 44161 gaatccttct tatgttcctt ttctatgttc acgccttgaa tgtggatgtt tacctcaacc 44221 acgttaaggc cggtcatagt ctcaatagcc ttttttactt tctcctgtat gttccaggat 44281 acctccggta tcctgcaccc gtattcaaca attatatata aatctattgc agcttccttg 44341 tccccgactt caacctttac tcctttggaa aggttcttcc ttcccagcat ttcagcaatt 44401 ccgccggcaa ttccaccgct catgccggcc actcccggaa cctccattgc agcaatgcca 44461 gcaataatag caacaacctc ttctgaaatt ttcaacgtac ctctgtcgtt agaacctccc 44521 tgtcctgcat ctcccacttg gaattacctc ctttgctgca atttaaccgt taggttttgc 44581 caacatcaaa tattataaca ccacggcatt atattatcaa ctttgtgaca taaatcttta 44641 gaatttattg cttacatgaa catcggagat atccactccg gcctgacggg aagttatttc 44701 cgcaatctgt gccacttcca ccgaggaaat acttggagct tttaccacaa catcaacgct 44761 tccgtcatcc ccgaaaaaca ccacaacgtc actaaaccct ttgtttttta tcaatgcttc 44821 aattctcatt tccttgtctg aattttccaa aagcttcagc attctttcat atgcctgggt 44881 tctttgctct tctgtggcat tggcatcatt ggtaatcttc tctaattcct ccttgtcttt 44941 ggccctcctt acatccttat ccatctttgc ctgggcaaaa aactcatttg cttccttgga 45001 agcctgaaga gccttgttgt cctgcttgtt ctctttcttg tcgctgtttt cactcttttc 45061 atccttcttt tcttctttat tcccggcttg cagatccgtt gtattgtcca cataccatgc 45121 ttcgcccagg ctttccgttt cttcatcaaa ctgacttacg gatatgtcat ccgaatcatt 45181 tcctgacgaa ccgctgttat tgtagctgta ctgtaaatac cccgctacaa caatcataag 45241 aatcaatgac aatacaacaa tttgttttct ctttaaaacc atcataaaat gatccccctt 45301 tatgacatat gtttatagta aactgttttt cagtaaatat atattatatt tccaaacatt 45361 ttatatctat aataaactgc atttgataaa tttattttcc cctttccaca acctgtatct 45421 tatgaacggg aatatcaagc aaaaccttga cggagttaac aaggttttcc tttaccgtcg 45481 catccgacgc accttccgca actaccagca ctccctttac ctccggcata agttcctttg 45541 ctataatggg ttttttcaca cccttgtcac tttcttcata gacaacactg ctttcataac 45601 tgctttgggc aatccttcgt gtgcctccgg cactgtcttt ttcattggtg ctgttgtcac 45661 ttctctttac gtccgtgtag gggactatct cctttcccga ggcataagtg atcattacac 45721 ttacctttcc caccccttgg attttttcca atatgttttc tatgtctttt tccaaatcgg 45781 atttttcatc gtcaacaccg atattcaaaa cttcccgggt attgtccaaa gcttcactgc 45841 ttttgacttt gttttcatct tttttcttgt cattgcctcc aaacaatgtt cctccggcta 45901 ttattataat catgccgatt ataataagta tgacaagatt ctctccccat ttgttgtttt 45961 tatctttgtc cagcatgttt ttaagacgct ctatagtttc ttttatcttg cccattttat 46021 cctcctcaat cctccataag agaaatcacg atattttctt ttggtacatt taaaagtttt 46081 attactttat cttcaagctc acgtctgatt ttttcatcag gttgtttttc caaaccctta 46141 ttgtctgagt tgtccacgga ttgtccaatg tcaactttca ccctctttac ctctaaaata 46201 tgttttactt gctcgctctc atcctccaaa gacagataca aataaacctt tttcacctct 46261 ccgaaccttt ccgatgtata gtcttcattg attatgacat cggcctctgc ctctttaact 46321 tccttaatat ccttagctac tgacttaagc tgagctatga ttttttccct gtacgcattg 46381 gttatctgcc ttatttgcct ctcttccaaa acctcgctgt ttatcatcac ctccttctta 46441 tctatgtaat tgctgcccgc cagctgaaac tccttaagat caatttcttt ttcaaacaac 46501 tccagcacag gatttataag accaatcacg agaataaacc cggtaaccag atttacaatt 46561 ttttttacct tacccgaagg cagcatcatt tctataagca tgacaaacac tacaagagtg 46621 acaatattta caacccagtt tcttaaaaaa tctatcattt tttcctccat ttattaaaat 46681 ttatcttatc attgtactga tattgcttgc caatatcagt gccgtaacag tcattaaaaa 46741 cataaacgcc accgatgccg caattcccaa aatatgagcc atggaaccgg caacatcgct 46801 tatacatttt ataattcttc cttccgccaa aggttccaaa agcacacagg ccattctgta 46861 caaaaggaca accgcaagta ttttgagcaa aggaagaagg catatgacta caatccctat 46921 cataatagcc actcccaccg cgttcttaat caaaagagtg cagccaatta ccgcgtcggc 46981 ggcatccgcc aaatattttc ccgccacggg aataaatgcg cctatggcaa atttggcagt 47041 cttgcttgtt actccgtcaa caaccgctcc caaagatccc tgaagcgata ctatcgctac 47101 aaatattgta agaatgaggc ctaatgtcca ttgagttata tttttcaaaa aacttgaaag 47161 tcttgatatt tgaatcttgt ccgatatatt gtccactatg gatatgatgg tggacagcac 47221 gataagaggt ataagtatat tctttattat tgtggcacta acttgcacca ccattataag 47281 cagcggctgc aacacacctc ccgatgaaat gtttccggat gatataatca acgtcaccaa 47341 aaccggtatc gacgaataca tgaagtttac catccggtct attatttccg ttccggactt 47401 taccacggag ctgaaactta ccaaaagtat ggataccagt actatatagc acacgtaaaa 47461 agccagttct ccgacacctt tgtttaaaaa agatgattga agattgttaa ggattgcgca 47521 caaagccacc aacaccataa gttttaccag gatgcccata tttaaataaa tctcttcaaa 47581 aagataagtc aaaattttgt ttattatatc cggcagattg aaatttaatt ttccttttgc 47641 cacatcacgg attatttttt caggatcata acccggcaag atttcatcga ttttttcatc 47701 tttgtatttt ttaagctctt tttccagtaa atccacttca tccgcttcaa tctgttcttc 47761 cataattttc tcttctatac tcttgtcctg ggcataagtt tcatcctcac cggcggcata 47821 cgccggcaaa gaaacaaaac acatggatgt aaatacagta acaaaaacga atactaaaat 47881 acatttggca taatatcttt tgtttttcat acaccttttc cccattcaga caattttatt 47941 gagtgaaatt gcataaaaca aattaatgtg cttttcattg aggcaaaatg ctgattataa 48001 gatccaacag cgaggttatt ataggtaccg ccattacaac aataataact tttcccgcaa 48061 gctccacttt tgacgctatt gccccttctc cggcatccct gcacacctcg gcgccaaatt 48121 cagctatata ggcaatgccc acaatcttta aaagggtatt tatataaacc atgtcaatgt 48181 tcactttttc cgcatagctg cttaacaagt ccacgaccgc cgtaattttt cccagtatga 48241 ccagaaaaat gattattccc gtaaccaggc tgatctgtaa agccatctcg ggtctgtggg 48301 ctttaagaag caaagctatt actgtagcaa ccaaagccaa tccgataatc tgaaatattt 48361 ccatttttat catccgcctc tgagaaatct taaaactgaa acagtgtttt tacggcatca 48421 aacaggtttg ctatttcctt tactatcatc atcaaaacca caaccaatcc cgccagtgtg 48481 gtcatcattg cctgttcttc ccttccggat ttgttcagca atgcattcaa aacagatacc 48541 aaaattccta ttgccgcaat tctgaaaatc aaatctatat tcatacttct ttttctcctc 48601 cgtgttttac ttttataaac actcttttcc cagccggaaa tcaagtttgc cttattagta 48661 caagtatatt cacggcatat taaaaattag aacaatataa tgattattgc cagacctcca 48721 agtatcccca aatttctgta catggcttca ttctttgctc tcagctcttc agctttttgt 48781 tcctggagtt tcaattgatt aatggtgagc cggatgttct ttatctgtcc ttctacgtct 48841 gagcttccga gcatttttcc gaaggaaata attatttcct cgtcctcttt gttcaaagat 48901 gtgttcttta tattttcctt gacggctttg gcccaggctt cgccggcagt tattcccgta 48961 tcgttttcaa gggcttccac cgtgcctttg aaaaaaactg caacactgct gtcatcatac 49021 atgtatattt ttgtaaaagc atcttttaaa acgttggaca taaagcttat ttcagtttca 49081 aacatctgaa gatatccctg cagagctctc agctccgctg gtctttttga gcaccgtctt 49141 gagtacatgt atcccaaaag gctgctcgac ataaaaacaa tcaggcttcc gataattttt 49201 agcagcatac tcattctcct ttgtacaaaa tactcatatc ggtcccgtca attatctctt 49261 ccactgtacc ggggcctttt ctcgcgctca aaacaatata cctttcaaac atcttttctt 49321 ctatcaggct caagacttct ttgcggcttt ttaattccga aatattgtac ccgtgcgccg 49381 tggatatcac tttcacccct gcattaagca cctgaatcaa agcatctttg tctcccttgt 49441 ttcctatttc atccgtaaca atcacatccg gcgacatgga tctgagcatc attatcatgc 49501 caatttgttt ggggcacgca tcaagcacat cggtccttgt tcctaccctg ttctggggca 49561 cccccttgta acatgctgca atttctgaac gttcatctac aactcccact ttaactcctt 49621 taaagcccat ttcttcaaca ccgtcgctga tagccctcgt tatgtctctt aacaaggttg 49681 ttttcccgca ttggggagga gatactatca aagtgttgta aacttgcttt tcactgctga 49741 taatatattt taaaactttc gaggaacatc cggttatttc cctggatatt cttatattaa 49801 gcccggaaac atccttgatg ttctttacgg tatctccgtt taaaacaact cgtccgacaa 49861 taccgaccct atggcctccc cttatggtca aaaaaccgtt tcttatttca tcctgaaaag 49921 cataaatgga gttttcactt ataagttcca gcgtttttgc tatctgctcc tggcttacat 49981 aaaaaagatt catcctgttt gctgtaagtc ttccttccaa attgacaaaa aagcttcctt 50041 tttcattttg aatcattaaa ggcttgttcg ctcttagtct tatctcttcg gtggttataa 50101 gttcatttag cggaatcttc tttaaaacat ctctcacttg tggagatatc attctcaaaa 50161 tgtccttttc aaagttctgt actttttcaa cgctgaaaac aaaatcttct tttgtaacca 50221 taaaaggccc ccctgttttc acatatcctt tttcgcgcat ccttaaggcc aaagcttgtt 50281 ttttgatatt tgatatttat taatatttga atttgtccaa ttttatgaca aaaaaataaa 50341 aggtaacggt caaaaaaaga a //