LOCUS       NZ_ACVX01000031        48256 bp    DNA     linear   CON 10-NOV-2010
DEFINITION  Clostridium thermocellum DSM 2360 ctg00058, whole genome shotgun
            sequence.
ACCESSION   NZ_ACVX01000031 NZ_ACVX00000000
VERSION     NZ_ACVX01000031.1  GI:256005470
DBLINK      Project: 55637
KEYWORDS    WGS.
SOURCE      Clostridium thermocellum DSM 2360
  ORGANISM  Clostridium thermocellum DSM 2360
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (bases 1 to 48256)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L.
            and Hemme,C.L.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The draft genome of Clostridium thermocellum DSM 2360
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 48256)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L.
            and Hemme,C.L.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800
            Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     PREDICTED REFSEQ: This record has not been reviewed and the
            function is unknown. The reference sequence was derived from
            ACVX01000031.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4085028
            Source DNA and Bacteria available from Christopher L. Hemme
            (hemmecl@ou.edu)
            Contacts: Christopher L. Hemme (hemmecl@ou.edu)
                 David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            
            ##Metadata-START##
            Organism Display Name :: Clostridium thermocellum DSM 2360
            Culture Collection ID :: DSM 2360
            GOLD Stamp ID         :: Gi02594
            Isolation Site        :: contaminant of Clostridium thermocellum
                                     strain LQ8
            Isolation Country     :: USA
            Oxygen Requirement    :: Anaerobe
            Cell Shape            :: Rod-shaped
            Motility              :: Motile
            Sporulation           :: Sporulating
            Temperature Range     :: Thermophile
            Temperature Optimum   :: 60 C
            Gram Staining         :: gram+
            Biotic Relationship   :: Free living
            Diseases              :: None
            Phenotypes            :: Cellulose degrader, Ethanogenic, Ethanol
                                     production
            Energy Source         :: Chemoorganotroph
            ##Metadata-END##
FEATURES             Location/Qualifiers
     source          1..48256
                     /organism="Clostridium thermocellum DSM 2360"
                     /mol_type="genomic DNA"
                     /strain="DSM 2360"
                     /isolation_source="contaminant of Clostridium thermocellum
                     strain LQ8"
                     /db_xref="taxon:572545"
     gene            complement(348..782)
                     /locus_tag="ClothDRAFT_2294"
     CDS             complement(348..782)
                     /locus_tag="ClothDRAFT_2294"
                     /inference="similar to AA sequence:KEGG:HRM2_02490"
                     /note="KEGG: dat:HRM2_02490 predicted anti-sigma
                     regulatory factor RsbW1 (serine/threonine protein kinase)"
                     /codon_start=1
                     /transl_table=11
                     /product="putative anti-sigma regulatory factor,
                     serine/threonine protein kinase"
                     /protein_id="ZP_05430433.1"
                     /db_xref="GI:256005471"
                     /translation="MKVLKTYNSKVSSQKENICFLVKDIMKFLSDSSDVSEDVLFEIK
                     VILNELLQNAIKHGNKEDASKSVEVSVGITADNHVYLIVEDEGEGYDLDCVCAKEEIP
                     EEVTDVCDLKENGWGILIVKNLCDRIRLNKKGNKVIVFKSLK"
     misc_feature    complement(360..>656)
                     /locus_tag="ClothDRAFT_2294"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cl00075"
                     /db_xref="CDD:185789"
     gene            complement(949..1707)
                     /locus_tag="ClothDRAFT_2295"
     CDS             complement(949..1707)
                     /locus_tag="ClothDRAFT_2295"
                     /inference="protein motif:TFAM:TIGR02980"
                     /note="TIGRFAM: RNA polymerase sigma-70 factor,
                     sigma-B/F/G subfamily; RNA polymerase sigma factor,
                     sigma-70 family;
                     PFAM: sigma-70 region 2 domain protein; sigma-70 region 3
                     domain protein; sigma-70 region 4 domain protein;
                     KEGG: hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase, sigma 28 subunit, Sig B/F/G
                     subfamily"
                     /protein_id="ZP_05430434.1"
                     /db_xref="GI:256005472"
                     /db_xref="InterPro:IPR000943"
                     /db_xref="InterPro:IPR007624"
                     /db_xref="InterPro:IPR007627"
                     /db_xref="InterPro:IPR007630"
                     /db_xref="InterPro:IPR014284"
                     /db_xref="InterPro:IPR014322"
                     /translation="MMDDAVNNNNVVNDSDELFREYKETKSVEVRNKIVSKYLYLSDI
                     LAKKFLNRGIDYEDIYQVVSIALIKAVERFDPDKGVKFISFATPTIIGEIKRYFRDKG
                     SVIRIPRRIYEVYQKINHARESLTQELKRPPRIDELARHLNISEESVVEIIESYNAYN
                     IQSFSQNVYANDELELHEVIGDQDSTFERIENRDFLEKSLDKFSDVEKEFISMRYFDN
                     KTQKDIAQKMGVSQMYISRLERKVLEKFRRMLAK"
     misc_feature    complement(958..1626)
                     /locus_tag="ClothDRAFT_2295"
                     /note="RNA polymerase sigma-70 factor, sigma-B/F/G
                     subfamily; Region: SigBFG; TIGR02980"
                     /db_xref="CDD:163094"
     misc_feature    complement(1402..1575)
                     /locus_tag="ClothDRAFT_2295"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:146937"
     misc_feature    complement(967..1122)
                     /locus_tag="ClothDRAFT_2295"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial...; Region:
                     Sigma70_r4; cd06171"
                     /db_xref="CDD:100119"
     misc_feature    complement(order(979..981,985..990,994..1002,1006..1011,
                     1015..1017,1045..1050,1066..1068,1096..1098))
                     /locus_tag="ClothDRAFT_2295"
                     /note="DNA binding residues"
                     /db_xref="CDD:100119"
     gene            complement(1710..2102)
                     /locus_tag="ClothDRAFT_2296"
     CDS             complement(1710..2102)
                     /locus_tag="ClothDRAFT_2296"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="putative anti-sigma regulatory factor,
                     serine/threonine protein kinase"
                     /protein_id="ZP_05430435.1"
                     /db_xref="GI:256005473"
                     /translation="MNSVCDKIELTLPFKAEYVSVARLVASGVCNRIGFDIETIEDIK
                     VAISEVCSKIVSMGSKITDNYTIIYGVSENTLNVEFVCDDPSIKCIFDEEKDGLAISI
                     ITALMDNVVLCDKSNRIISMSKVLEGNR"
     misc_feature    complement(1725..2102)
                     /locus_tag="ClothDRAFT_2296"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cl00075"
                     /db_xref="CDD:185789"
     gene            complement(2115..2429)
                     /locus_tag="ClothDRAFT_2297"
     CDS             complement(2115..2429)
                     /locus_tag="ClothDRAFT_2297"
                     /inference="protein motif:TFAM:TIGR00377"
                     /note="TIGRFAM: anti-anti-sigma factor;
                     PFAM: Sulfate transporter/antisigma-factor antagonist
                     STAS;
                     KEGG: dat:HRM2_02120 predicted anti-anti-sigma factor
                     (ant-sigma factor regulator)"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-factor antagonist"
                     /protein_id="ZP_05430436.1"
                     /db_xref="GI:256005474"
                     /db_xref="InterPro:IPR002645"
                     /db_xref="InterPro:IPR003658"
                     /translation="MSEGLRFVEEKVDDSVKLSLFGEVDIYTSQELKEKLYSIVDNNQ
                     TDLIIDCKELNYIDSTGLGIFVGALKKTKQYGKKIIITSLKDNIKKLFIITGLDKVFV
                     IE"
     misc_feature    complement(2121..2411)
                     /locus_tag="ClothDRAFT_2297"
                     /note="Sulphate Transporter and Anti-Sigma factor
                     antagonist) domain of anti-anti-sigma factors, key
                     regulators of anti-sigma factors by phosphorylation;
                     Region: STAS_anti-anti-sigma_factors; cd07043"
                     /db_xref="CDD:132914"
     misc_feature    complement(order(2139..2141,2145..2150,2160..2162,
                     2226..2231,2238..2246,2250..2258,2262..2264,2331..2333,
                     2349..2357,2361..2363))
                     /locus_tag="ClothDRAFT_2297"
                     /note="anti sigma factor interaction site; other site"
                     /db_xref="CDD:132914"
     misc_feature    complement(2253..2255)
                     /locus_tag="ClothDRAFT_2297"
                     /note="regulatory phosphorylation site; other site"
                     /db_xref="CDD:132914"
     gene            complement(2778..3257)
                     /locus_tag="ClothDRAFT_2298"
     CDS             complement(2778..3257)
                     /locus_tag="ClothDRAFT_2298"
                     /inference="protein motif:TFAM:TIGR01462"
                     /note="TIGRFAM: transcription elongation factor GreA;
                     PFAM: transcription elongation factor GreA/GreB domain
                     protein;
                     KEGG: transcription elongation factor"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="ZP_05430437.1"
                     /db_xref="GI:256005475"
                     /db_xref="InterPro:IPR001437"
                     /db_xref="InterPro:IPR006359"
                     /translation="MATNKEVVLTYEGLQKLEQELENLKTVKRREVAERIKQALSFGD
                     ISENSEYDEAKNEQAYIEGRIFQLENMLKNAKVIDEEDIQTDVVSIGSKVKVLDMEFD
                     EEVEYYIVGSTEADPSQYKISNESPVGKALIGGKIGDIVEVTVPDGVIKFKILEIRK"
     misc_feature    complement(2784..3248)
                     /locus_tag="ClothDRAFT_2298"
                     /note="transcription elongation factor GreA; Reviewed;
                     Region: greA; PRK00226"
                     /db_xref="CDD:178936"
     misc_feature    complement(3027..>3182)
                     /locus_tag="ClothDRAFT_2298"
                     /note="domain; Region: GreA_GreB_N; pfam03449"
                     /db_xref="CDD:146205"
     misc_feature    complement(2784..3011)
                     /locus_tag="ClothDRAFT_2298"
                     /note="C-term; Region: GreA_GreB; pfam01272"
                     /db_xref="CDD:144753"
     gene            complement(3586..4512)
                     /locus_tag="ClothDRAFT_2299"
     CDS             complement(3586..4512)
                     /locus_tag="ClothDRAFT_2299"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430438.1"
                     /db_xref="GI:256005476"
                     /translation="MTGRKAKKGDLIKRILNVLRSFFSTKLSDDAVKKAELYDGFNVF
                     TVRLPYKASELERPGRFKIRRLKKIIKRLCLDYSIEKCYFPHCAPDKLDIDFCVKDPF
                     FGRFLYKALLVNILKLISEKKGKDIRELDVAIIHGNDYTFLHSYIKILSSILKFLTII
                     THEKESIENMTDNIFEETGLAVRVTDNLAGGMKDAEAVINLADLGDFDIPGKMKFNEP
                     VVNYGSINTDKIKFTDIINSVDVILPGKFEEKLGKDVYKFYKRIELAEIILLNRLEIG
                     TCTINNNLDYAVLEKLARQFERDGFGFIPVIS"
     gene            complement(4616..6367)
                     /locus_tag="ClothDRAFT_2300"
     CDS             complement(4616..6367)
                     /locus_tag="ClothDRAFT_2300"
                     /inference="protein motif:PFAM:PF00704"
                     /note="PFAM: glycoside hydrolase family 18; copper amine
                     oxidase domain protein;
                     SMART: chitinase II;
                     KEGG: hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 18"
                     /protein_id="ZP_05430439.1"
                     /db_xref="GI:256005477"
                     /db_xref="InterPro:IPR001223"
                     /db_xref="InterPro:IPR001579"
                     /db_xref="InterPro:IPR011583"
                     /db_xref="InterPro:IPR012854"
                     /translation="MKKKILGCFVIVVLLAVLAAIPLAGYYLYFKPNDEVVPAFAEGE
                     LVLVVEGEKVLSKNSPKILEGEVLLPFDIVKEYFDPHIFWDEALGKVTITTKDRVIRM
                     KTDKLDAIVNNQPITLNIPVTVENDVVYIPIEFLAEFYGIEVSYVEKSNVVIIDYKNS
                     IKQIAEPIDPEAVVRKGRSIREPIIRKFDLSSGDTAENTLRIFEEYDKWYKVRTWDGA
                     IGYIEKRFVVVKKLMVEKISDDKTPKPAWTPPKGKINLAWDMIYTRREDHSSLGEMKG
                     LDVISPTWFQVKNAKGELINRAYSKYVDWAHSRGYQVWALLSNDFTDSEMTSKFLNNT
                     DARDNLIREILAYAALYNLDGINIDFENMYISDRDVFTQFVREIAPLLREQGLVVSVD
                     VNDIQCYDKKALSEAVDYIMYMSYDQHWSTSPVAGSVAQVSWQEKIVKRVLEQEGVPR
                     EKLLLGIPFYTRLWKETVDESGKKKLTSSALTMKQAKNLIIENNAKVEWDEESGQFYA
                     EYTKDNTNYRLWLEDANSINLRTSLVHKYRLAGTCAWSIYFVSEDIWDVLNKNLKEIE
                     SYQEWLEQNRNNQYKFP"
     sig_peptide     complement(6308..6367)
                     /locus_tag="ClothDRAFT_2300"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 1.000) with cleavage site probability 0.867 at
                     residue 20"
     misc_feature    complement(5903..6178)
                     /locus_tag="ClothDRAFT_2300"
                     /note="Copper amine oxidase N-terminal domain; Region:
                     Cu_amine_oxidN1; pfam07833"
                     /db_xref="CDD:149091"
     misc_feature    complement(4694..5602)
                     /locus_tag="ClothDRAFT_2300"
                     /note="Cortical fragment-lytic enzyme (CFLE) is a
                     peptidoglycan hydrolase involved in  bacterial endospore
                     germination.  CFLE is expressed as an inactive preprotein
                     (called SleB) in the forespore compartment of sporulating
                     cells.  SleB translocates across the...; Region:
                     GH18_CFLE_spore_hydrolase; cd02874"
                     /db_xref="CDD:119353"
     misc_feature    complement(order(4733..4735,4988..4990,5117..5122,
                     5126..5128,5285..5287,5291..5293,5297..5299,5402..5404,
                     5516..5521,5585..5587))
                     /locus_tag="ClothDRAFT_2300"
                     /note="active site"
                     /db_xref="CDD:119353"
     gene            complement(6531..7019)
                     /locus_tag="ClothDRAFT_2301"
     CDS             complement(6531..7019)
                     /locus_tag="ClothDRAFT_2301"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430440.1"
                     /db_xref="GI:256005478"
                     /translation="MDIFVEKLVKKKLDGNDMLIIGGSIALAVVVISAIILFLGPYGA
                     SLILCLAVVYLTYMVISSRRIEYEYAFTNGELDIDKIVNKRKRENLISANCREFEIFA
                     KADSDKISKYLEEIEDRIMAVSSLDSEDIYVFVAKKKIDEDEDRTKSKRVLVFLNPTK
                     KC"
     gene            complement(7053..8108)
                     /locus_tag="ClothDRAFT_2302"
     CDS             complement(7053..8108)
                     /locus_tag="ClothDRAFT_2302"
                     /inference="protein motif:PFAM:PF07238"
                     /note="PFAM: type IV pilus assembly PilZ"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver modulated PilZ
                     sensor protein"
                     /protein_id="ZP_05430441.1"
                     /db_xref="GI:256005479"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR009875"
                     /translation="MSVISVSKEELFNVMQYTNLVRVRFENDDVWTVLPILYAGEDQV
                     DILVDASKITLPGDVCGKAVIKFQSKGYEYIINGHIDNKSEDAPATVTIKYIDAKKYY
                     NLRKHIRFDVNINSRIKEKDAGQKCESSWKEATVRNISKGGAMFVSNVKLDFNSMIDM
                     KLYFDSSKEFVTSAKILRVSELGNGEFGYGVQFAGMSKENWDILNTELLKFEEKYFKS
                     LSIFREYKRTSDMRFDTKIVIFSSDIDESYDIRESLIKLGAENFDVINNFKFYFDYLT
                     EEKPKLVIIDTNTLNDEVVDTVRNIKTDFPDMHVQIILPIELMEEDILGTLATEDEIL
                     FKPLIYNEFEDRIIKYL"
     misc_feature    complement(7497..7802)
                     /locus_tag="ClothDRAFT_2302"
                     /note="PilZ domain; Region: PilZ; cl01260"
                     /db_xref="CDD:163963"
     misc_feature    complement(<7068..>7415)
                     /locus_tag="ClothDRAFT_2302"
                     /note="Response regulator containing a CheY-like receiver
                     domain and a GGDEF domain [Signal transduction
                     mechanisms]; Region: PleD; COG3706"
                     /db_xref="CDD:33501"
     gene            complement(8235..8387)
                     /locus_tag="ClothDRAFT_2303"
     CDS             complement(8235..8387)
                     /locus_tag="ClothDRAFT_2303"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430442.1"
                     /db_xref="GI:256005480"
                     /translation="MERAWAECTNLNRAINVDKQREILVVKGLSFIYVLLCVPRYYLF
                     LSKNLK"
     gene            complement(8359..9984)
                     /locus_tag="ClothDRAFT_2304"
     CDS             complement(8359..9984)
                     /locus_tag="ClothDRAFT_2304"
                     /inference="protein motif:TFAM:TIGR02348"
                     /note="TIGRFAM: chaperonin GroEL;
                     PFAM: chaperonin Cpn60/TCP-1;
                     KEGG: gur:Gura_4307 chaperonin GroEL"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="ZP_05430443.1"
                     /db_xref="GI:256005481"
                     /db_xref="InterPro:IPR001844"
                     /db_xref="InterPro:IPR002423"
                     /db_xref="InterPro:IPR012723"
                     /translation="MAKQIKFGEEARRALERGVNQLADTVKVTLGPKGRNVVLDKKFG
                     SPMITNDGVTIAKEIELEDPFENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREG
                     LKNVAAGANPMLLKKGIAKAVDAAVEGIKEISQKVKGKEDIARVASISANDEVIGELI
                     ADAMEKVTNDGVITVEEAKTMGTNLEIVEGMQFDRGYVSPYMVTDTEKMEAVLDEPYI
                     LITDKKISNIQDILPLLEQIVQQGKKLVIIAEDVEGEALATLLVNKLRGTFTCVAVKA
                     PGFGDRRKAMLEDIAILTGGQVITSDLGLELKDTTVEQLGRARQVKVQKENTIIVDGA
                     GDPKEIQKRIASIKSQIEETTSDFDREKLQERLAKLAGGVAVIQVGAATETEMKEKKL
                     RIEDALAATKAAVEEGIVAGGGTALVNVIPKVAKVLDTVSGDEKTGVQIILRALEEPV
                     RQIAENAGLEGSVIVEKVKASEPGIGFDAYNEKYVNMIEAGIVDPAKVTRSALQNAAS
                     VASMVLTTESVVADIPEKETSGGPGGAGMGGMY"
     misc_feature    complement(8404..9984)
                     /locus_tag="ClothDRAFT_2304"
                     /note="chaperonin GroEL; Reviewed; Region: groEL;
                     PRK12849"
                     /db_xref="CDD:183791"
     misc_feature    complement(8419..9978)
                     /locus_tag="ClothDRAFT_2304"
                     /note="GroEL_like type I chaperonin. Chaperonins are
                     involved in productive folding of proteins. They share a
                     common general morphology, a double toroid of 2 stacked
                     rings, each composed of 7-9 subunits. The symmetry of type
                     I is seven-fold and they are found...; Region: GroEL;
                     cd03344"
                     /db_xref="CDD:48161"
     misc_feature    complement(order(8422..8442,8449..8451,8611..8613,
                     8833..8835,8839..8841,9220..9222,9304..9306,9400..9402,
                     9760..9762,9769..9771,9781..9783,9805..9807,9811..9813,
                     9841..9843,9847..9852,9865..9867,9871..9882,9913..9915,
                     9964..9966,9976..9978))
                     /locus_tag="ClothDRAFT_2304"
                     /note="ring oligomerisation interface; other site"
                     /db_xref="CDD:48161"
     misc_feature    complement(order(8503..8505,8509..8511,8626..8628,
                     8746..8748,8797..8799,9538..9540,9715..9717,9727..9729,
                     9889..9897))
                     /locus_tag="ClothDRAFT_2304"
                     /note="ATP/Mg binding site; other site"
                     /db_xref="CDD:48161"
     misc_feature    complement(order(8587..8589,8596..8601,8605..8607,
                     8632..8634,8686..8688,9661..9663))
                     /locus_tag="ClothDRAFT_2304"
                     /note="stacking interactions; other site"
                     /db_xref="CDD:48161"
     misc_feature    complement(order(8761..8766,8866..8868,9412..9414,
                     9433..9435,9565..9567))
                     /locus_tag="ClothDRAFT_2304"
                     /note="hinge regions; other site"
                     /db_xref="CDD:48161"
     gene            complement(10033..10317)
                     /locus_tag="ClothDRAFT_2305"
     CDS             complement(10033..10317)
                     /locus_tag="ClothDRAFT_2305"
                     /inference="protein motif:PFAM:PF00166"
                     /note="PFAM: chaperonin Cpn10;
                     KEGG: sat:SYN_00062 co-chaperonin"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin Cpn10"
                     /protein_id="ZP_05430444.1"
                     /db_xref="GI:256005482"
                     /db_xref="InterPro:IPR001476"
                     /translation="MNIRPLGDRVVVKMVETEETTKSGIVLPGSAKEKPQVAEVVAVG
                     PGTVVDGKEVKMEVKVGDKVIISKYAGTEVKFDGQEYTILRQNDILAVVE"
     misc_feature    complement(10039..10314)
                     /locus_tag="ClothDRAFT_2305"
                     /note="Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10
                     cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase,
                     to assist the folding and assembly of proteins and is
                     found in eubacterial cytosol, as well as in the matrix of
                     mitochondria and chloroplasts...; Region: cpn10; cd00320"
                     /db_xref="CDD:73192"
     misc_feature    complement(order(10042..10050,10096..10098,10102..10104,
                     10117..10119,10147..10149,10207..10212,10291..10293,
                     10300..10302,10306..10308,10312..10314))
                     /locus_tag="ClothDRAFT_2305"
                     /note="oligomerisation interface; other site"
                     /db_xref="CDD:73192"
     misc_feature    complement(10225..10266)
                     /locus_tag="ClothDRAFT_2305"
                     /note="mobile loop; other site"
                     /db_xref="CDD:73192"
     misc_feature    complement(order(10153..10155,10183..10185))
                     /locus_tag="ClothDRAFT_2305"
                     /note="roof hairpin; other site"
                     /db_xref="CDD:73192"
     gene            complement(10540..11709)
                     /locus_tag="ClothDRAFT_2306"
     CDS             complement(10540..11709)
                     /locus_tag="ClothDRAFT_2306"
                     /inference="protein motif:PFAM:PF04326"
                     /note="PFAM: AAA-4 family protein;
                     KEGG: lpn:lpg2559 ATP-dependent DNA helicase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulator"
                     /protein_id="ZP_05430445.1"
                     /db_xref="GI:256005483"
                     /db_xref="InterPro:IPR007421"
                     /translation="MDCHKLRRLLKKEEGPKLDFKAEYDLSTESGKKELTKDVIAIAN
                     SRGGRGYIILGIEDKTKRVLGIEPKRYTEEQIQQIIYNRCDPPVPISVDFVGLDGKTV
                     GVITVYRSSHKPHQMIQNGAFYIRRGSTTDIARRSEIANLFQENGLMTYETVILKNVG
                     MEELDFGLIKDYFKTLNVFSDNPSELILEALGIIGQKSDTEEYHPTIGGLLLFGKNPS
                     LYLPHVYVKVVYNGEARLFFGNILKMLDDVSDYMRSIIKVEGYPFNALEEVIANALVH
                     RDYLDVSKGIVITVTDKNIEISNPGALIAGNSVYSFSREINPDRRNPWLYQRLLTLDP
                     KKRFMKSGVGLKRVKKSFTGIGPVKFINIGSQNLFKVLLPIGKKQESTSDTSGLF"
     misc_feature    complement(10570..11709)
                     /locus_tag="ClothDRAFT_2306"
                     /note="Predicted transcriptional regulator containing an
                     HTH domain and an uncharacterized domain shared with the
                     mammalian protein Schlafen [Transcription]; Region:
                     COG2865"
                     /db_xref="CDD:32692"
     misc_feature    complement(11308..11670)
                     /locus_tag="ClothDRAFT_2306"
                     /note="Divergent AAA domain; Region: AAA_4; pfam04326"
                     /db_xref="CDD:146784"
     gene            complement(11733..12395)
                     /locus_tag="ClothDRAFT_2307"
     CDS             complement(11733..12395)
                     /locus_tag="ClothDRAFT_2307"
                     /inference="protein motif:TFAM:TIGR03188"
                     /note="TIGRFAM: phosphoribosyl-ATP diphosphatase;
                     PFAM: phosphoribosyl-AMP cyclohydrolase;
                     phosphoribosyl-ATP pyrophosphohydrolase;
                     KEGG: nam:NAMH_1557 histidine biosynthesis bifunctional
                     protein hisIE"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP diphosphatase"
                     /protein_id="ZP_05430446.1"
                     /db_xref="GI:256005484"
                     /db_xref="InterPro:IPR002496"
                     /db_xref="InterPro:IPR008179"
                     /translation="MENILKELKFDDRGLIPVITQDYKTNEVLMMAYMNEEALKKSLE
                     TGKVHYFSRSRNKLWLKGETSGHFQLIKSISIDCDADTLLIKVEQVEAACHTGHYSCF
                     YREISGNELKETSDKVFDEQKVYEAENAKILQEIYDVIVDRTIHPKEGSYTNYLFEKG
                     LDKILKKVGEEAAEVIIGAKNRDKGEIVYEISDLIYHLLVLMVERGIKLEDIYEELRK
                     RR"
     misc_feature    complement(11736..12395)
                     /locus_tag="ClothDRAFT_2307"
                     /note="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein;
                     Reviewed; Region: PRK02759"
                     /db_xref="CDD:179470"
     misc_feature    complement(12018..12392)
                     /locus_tag="ClothDRAFT_2307"
                     /note="Phosphoribosyl-AMP cyclohydrolase; Region: PRA-CH;
                     cl00344"
                     /db_xref="CDD:185924"
     misc_feature    complement(11736..12011)
                     /locus_tag="ClothDRAFT_2307"
                     /note="Phosphoribosyl-ATP pyrophosphohydrolase; Region:
                     PRA-PH; cl00345"
                     /db_xref="CDD:185925"
     gene            complement(12417..13178)
                     /locus_tag="ClothDRAFT_2308"
     CDS             complement(12417..13178)
                     /locus_tag="ClothDRAFT_2308"
                     /inference="protein motif:TFAM:TIGR00735"
                     /note="TIGRFAM: imidazoleglycerol phosphate synthase,
                     cyclase subunit;
                     PFAM: histidine biosynthesis protein;
                     KEGG: ppd:Ppro_3055 imidazole glycerol phosphate synthase
                     subunit HisF"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol phosphate synthase, cyclase
                     subunit"
                     /protein_id="ZP_05430447.1"
                     /db_xref="GI:256005485"
                     /db_xref="InterPro:IPR004651"
                     /db_xref="InterPro:IPR006062"
                     /translation="MVTKRIIPCLDVHNGRVVKGVNFVNIRDAGDPVEIASYYDKAGA
                     DELTFLDITASAEARNIMIDVVRRVAEQVFIPFTVGGGIRTVEDFREILKAGADKVSI
                     NSAAVKRPELISEAASRFGSQCVVVAIDAKRRDDNSGWDVYINGGRINTGKDAVEWAV
                     EVEKLGAGEILLTSMDCDGTKKGYDIELTRKVSESVRIPVIASGGAGTMEHFREALVE
                     GKADAVLAASLFHYREIEIMELKKYLKENGIEIRM"
     misc_feature    complement(12420..13178)
                     /locus_tag="ClothDRAFT_2308"
                     /note="Imidazoleglycerol-phosphate synthase [Amino acid
                     transport and metabolism]; Region: HisF; COG0107"
                     /db_xref="CDD:30456"
     misc_feature    complement(12438..13169)
                     /locus_tag="ClothDRAFT_2308"
                     /note="The cyclase subunit of imidazoleglycerol phosphate
                     synthase (HisF). Imidazole glycerol phosphate synthase
                     (IGPS) catalyzes the fifth step of histidine biosynthesis,
                     the formation of the imidazole ring. IGPS converts
                     N1-(5'-phosphoribulosyl)-formimino-5-; Region: HisF;
                     cd04731"
                     /db_xref="CDD:73393"
     misc_feature    complement(order(12495..12500,12564..12572,12642..12647,
                     12660..12662,12741..12743,12789..12791,12795..12797,
                     12867..12872,12933..12935,13029..13031,13122..13124))
                     /locus_tag="ClothDRAFT_2308"
                     /note="substrate binding site; other site"
                     /db_xref="CDD:73393"
     misc_feature    complement(order(12513..12515,12588..12590,12672..12674,
                     12810..12812,12882..12887,12894..12896,12951..12953,
                     12957..12959,12966..12968,12978..12980,13044..13046,
                     13059..13061))
                     /locus_tag="ClothDRAFT_2308"
                     /note="glutamase interaction surface; other site"
                     /db_xref="CDD:73393"
     gene            complement(13191..13904)
                     /locus_tag="ClothDRAFT_2309"
     CDS             complement(13191..13904)
                     /locus_tag="ClothDRAFT_2309"
                     /EC_number="5.3.1.16"
                     /inference="protein motif:TFAM:TIGR00007"
                     /note="KEGG: glo:Glov_1019
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]
                     imidazole-4-carboxamide isomerase;
                     TIGRFAM: phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribotide isomerase;
                     PFAM: histidine biosynthesis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribotide isomerase"
                     /protein_id="ZP_05430448.1"
                     /db_xref="GI:256005486"
                     /db_xref="InterPro:IPR006062"
                     /db_xref="InterPro:IPR006063"
                     /translation="MIIYPAVDIKDGRCVRLVQGEFDKVTVYSDNPVEMGLKWERMGA
                     QYLHVVDLDGARTGQIQNTPIISEMAVKLGIPVQLGGGIRTVETIETLLCKGIHRVIL
                     GTSAVKNPELVKQALKTFEDSVVIGIDAKDGMVAIEGWAKTSEFTAIGFAKKMEELGA
                     KTIIYTDISRDGMLAGPNLKAMEEMVKAVNIEVIASGGVRNIDDIRNLKNVGVSGVIV
                     GKALYTGDLDLKEAIEVAK"
     misc_feature    complement(13203..13901)
                     /locus_tag="ClothDRAFT_2309"
                     /note="HisA.  Phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribonucleotide (ProFAR) isomerase catalyzes
                     the fourth step in histidine biosynthesis, an
                     isomerisation of the aminoaldose moiety of ProFAR to the
                     aminoketose of PRFAR (N-(5'-phospho-D-1'-...; Region:
                     HisA; cd04732"
                     /db_xref="CDD:73394"
     misc_feature    complement(13212..13898)
                     /locus_tag="ClothDRAFT_2309"
                     /note="phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribotide isomerase; Region: TIGR00007"
                     /db_xref="CDD:161661"
     misc_feature    complement(order(13518..13520,13761..13763,13881..13883))
                     /locus_tag="ClothDRAFT_2309"
                     /note="catalytic residues; other site"
                     /db_xref="CDD:73394"
     gene            complement(13972..14592)
                     /locus_tag="ClothDRAFT_2310"
     CDS             complement(13972..14592)
                     /locus_tag="ClothDRAFT_2310"
                     /inference="protein motif:TFAM:TIGR01855"
                     /note="TIGRFAM: imidazole glycerol phosphate synthase,
                     glutamine amidotransferase subunit;
                     PFAM: glutamine amidotransferase class-I; CobB/CobQ domain
                     protein glutamine amidotransferase; SNO glutamine
                     amidotransferase;
                     KEGG: geo:Geob_0691 imidazole glycerol phosphate synthase,
                     glutamine amidotransferase subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase, glutamine
                     amidotransferase subunit"
                     /protein_id="ZP_05430449.1"
                     /db_xref="GI:256005487"
                     /db_xref="InterPro:IPR000991"
                     /db_xref="InterPro:IPR002161"
                     /db_xref="InterPro:IPR010139"
                     /db_xref="InterPro:IPR011698"
                     /db_xref="InterPro:IPR011702"
                     /translation="MIAVIDYGVGNLKSVEKAFQFIGYDARTTSDKELILNADSVVLP
                     GVGAFADAMDSLSKSGMIEVIQKVIDSGKPFLGICLGMQLLFEYSEEGGQNKKGLGIL
                     KGAIKQLPFGMNLKVPHMGWNSLELKNKSLLFDGLPQKPYVYFVHSYYLDTDDEDIVI
                     AKTNYGINFSVAVQKQNVFATQFHPEKSGEVGLKILKNFAGIISNK"
     misc_feature    complement(13984..14592)
                     /locus_tag="ClothDRAFT_2310"
                     /note="imidazole glycerol phosphate synthase subunit HisH;
                     Provisional; Region: hisH; PRK13141"
                     /db_xref="CDD:183868"
     misc_feature    complement(13996..14589)
                     /locus_tag="ClothDRAFT_2310"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in imidazole glycerol phosphate synthase (IGPS);
                     Region: GATase1_IGP_Synthase; cd01748"
                     /db_xref="CDD:153219"
     misc_feature    complement(order(14035..14037,14041..14043,14350..14364,
                     14452..14475))
                     /locus_tag="ClothDRAFT_2310"
                     /note="putative active site; other site"
                     /db_xref="CDD:153219"
     misc_feature    complement(14452..14475)
                     /locus_tag="ClothDRAFT_2310"
                     /note="oxyanion strand; other site"
                     /db_xref="CDD:153219"
     misc_feature    complement(order(14035..14037,14041..14043,14356..14358))
                     /locus_tag="ClothDRAFT_2310"
                     /note="catalytic triad; other site"
                     /db_xref="CDD:153219"
     gene            complement(14674..15558)
                     /locus_tag="ClothDRAFT_2311"
     CDS             complement(14674..15558)
                     /locus_tag="ClothDRAFT_2311"
                     /EC_number="6.3.2.6"
                     /inference="protein motif:TFAM:TIGR00081"
                     /note="KEGG: geo:Geob_3487
                     phosphoribosylaminoimidazole-succinocarboxamide synthase;
                     TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide
                     synthase;
                     PFAM: SAICAR synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole-succinocarboxamide
                     synthase"
                     /protein_id="ZP_05430450.1"
                     /db_xref="GI:256005488"
                     /db_xref="InterPro:IPR001636"
                     /translation="MLLGDTNFIDLPLYIKGKVRNVYDLGDKLLIVVTDRISAFDVVF
                     PNLIPNKGKVLNGISKFWFDYTRDIVDNHVITTDVSEYPEGLSKFKEELEGRSMLVKK
                     IKMIPAECIVRGYLEGSGLKDYKATGSICGIKLPEGLRQADKLPEPIFTPSTKETEGH
                     DQNVSFEGLCNAIGTELATKLRDISLALYEKASKYAESRGIILADTKFEFGILDGKIV
                     LGDELFTPDSSRFWDMNEYEPGRAQKSFDKQFVREYLESIGWDKKPPAPTLPDDVVKN
                     TELKYIEAYERITGNKFA"
     misc_feature    complement(14689..15522)
                     /locus_tag="ClothDRAFT_2311"
                     /note="non-metazoan
                     5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide
                     (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414"
                     /db_xref="CDD:133469"
     misc_feature    complement(order(14896..14901,14932..14934,15094..15096,
                     15244..15246,15250..15252,15256..15258,15340..15342,
                     15466..15468,15472..15474,15490..15495,15499..15501,
                     15505..15510,15514..15519))
                     /locus_tag="ClothDRAFT_2311"
                     /note="ATP binding site; other site"
                     /db_xref="CDD:133469"
     misc_feature    complement(order(14869..14880,14896..14898,14932..14934,
                     14938..14946,15076..15078,15094..15096,15100..15102,
                     15202..15210,15220..15222,15226..15228,15232..15234,
                     15244..15246,15250..15261,15337..15339,15436..15438,
                     15472..15474,15493..15495,15499..15510,15514..15516))
                     /locus_tag="ClothDRAFT_2311"
                     /note="active site"
                     /db_xref="CDD:133469"
     misc_feature    complement(order(14869..14880,14938..14946,15076..15078,
                     15100..15102,15202..15210,15220..15222,15226..15228,
                     15232..15234,15436..15438))
                     /locus_tag="ClothDRAFT_2311"
                     /note="substrate binding site; other site"
                     /db_xref="CDD:133469"
     gene            complement(15661..16248)
                     /locus_tag="ClothDRAFT_2312"
     CDS             complement(15661..16248)
                     /locus_tag="ClothDRAFT_2312"
                     /EC_number="4.2.1.19"
                     /inference="protein motif:PRIAM:4.2.1.19"
                     /note="PFAM: imidazoleglycerol-phosphate dehydratase;
                     KEGG: gur:Gura_4056 imidazoleglycerol-phosphate
                     dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="Imidazoleglycerol-phosphate dehydratase"
                     /protein_id="ZP_05430451.1"
                     /db_xref="GI:256005489"
                     /db_xref="InterPro:IPR000807"
                     /translation="MDRKFEVSRKTGETDITLSINIDGSGKSNISTGVGFFDHMLNLF
                     AKHGLFDLDVKAKGDLEIDAHHTVEDVGIVLGQAIKQALGEKKSIRRYGSSFVPMDEA
                     LVLVALDLSGRPYLVFDAELKCEKLGNMETELVEEFFRAVAFNAGITLHVKALYGSNT
                     HHIIEAMFKAFGRALDDATRKDDRIEGVMSTKGML"
     misc_feature    complement(15664..16233)
                     /locus_tag="ClothDRAFT_2312"
                     /note="Imidazoleglycerol-phosphate dehydratase; Region:
                     IGPD; cd07914"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(15754..15756,15763..15768,15838..15840,
                     15910..15912,15949..15954,15976..15978,16042..16044,
                     16051..16056,16108..16113,16120..16122,16132..16134,
                     16210..16212))
                     /locus_tag="ClothDRAFT_2312"
                     /note="putative active site pocket; other site"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(15763..15777,15838..15843,15850..15852,
                     15856..15858,15865..15879,16051..16056,16060..16068,
                     16132..16134,16141..16146))
                     /locus_tag="ClothDRAFT_2312"
                     /note="4-fold oligomerization interface; other site"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(15754..15756,15763..15768,15838..15840,
                     16042..16044,16051..16056,16132..16134))
                     /locus_tag="ClothDRAFT_2312"
                     /note="metal binding residues; metal-binding site"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(15703..15705,15721..15723,15730..15732,
                     15784..15786,15790..15792,15796..15798,15802..15804,
                     15904..15906,15910..15912,15922..15930,15940..15945,
                     15949..15957,15961..15969,15973..15975,15979..15981))
                     /locus_tag="ClothDRAFT_2312"
                     /note="3-fold/trimer interface; other site"
                     /db_xref="CDD:153419"
     gene            complement(16361..17437)
                     /locus_tag="ClothDRAFT_2313"
     CDS             complement(16361..17437)
                     /locus_tag="ClothDRAFT_2313"
                     /inference="protein motif:TFAM:TIGR01141"
                     /note="TIGRFAM: histidinol-phosphate aminotransferase;
                     PFAM: aminotransferase class I and II; Allinase-like;
                     KEGG: lhk:LHK_00185 His8"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase"
                     /protein_id="ZP_05430452.1"
                     /db_xref="GI:256005490"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR005861"
                     /db_xref="InterPro:IPR006948"
                     /translation="MIKDLVRPELQKLVPYVSHQVPYRIKLDANESPFELPESIRKKL
                     ADYFLKGPGLNIYPDNESVELRKTIAKYWNVDADEVIVGTGSNQLIQLIITVFVGKGE
                     KVLYPWPTFSMYKINTLIAGGEPVAFPLDKEKDFVLDTDKFIEAVKTENAKVVFLCNP
                     NNPTGGLVPLEHIEKIVKECKSSIIVVDEAYAEFCPQSVIPLVKKYENLVVLRTFSKA
                     YLLAGARCGYSISGIEIANEINKVRPTYNVSSLTQLIAKMVFEEQEEMQKMIRYLIEQ
                     RGELEKSLKKIKDVCIYPSHANYILVKVPEAEMISKELQKRGILIRSFPNDPVLYDCI
                     RITVGTKEQNDIFLEEFSDIINNF"
     misc_feature    complement(16385..17419)
                     /locus_tag="ClothDRAFT_2313"
                     /note="histidinol-phosphate aminotransferase; Region:
                     hisC; TIGR01141"
                     /db_xref="CDD:162223"
     misc_feature    complement(16391..17365)
                     /locus_tag="ClothDRAFT_2313"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(16763..16765,16787..16792,16796..16798,
                     16865..16867,16952..16954,17105..17107,17177..17185))
                     /locus_tag="ClothDRAFT_2313"
                     /note="pyridoxal 5'-phosphate binding site; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(16673..16675,16682..16684,16763..16771,
                     16886..16888,17075..17077,17174..17176))
                     /locus_tag="ClothDRAFT_2313"
                     /note="homodimer interface; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(16787..16789)
                     /locus_tag="ClothDRAFT_2313"
                     /note="catalytic residue; other site"
                     /db_xref="CDD:99734"
     gene            complement(17672..18979)
                     /locus_tag="ClothDRAFT_2314"
     CDS             complement(17672..18979)
                     /locus_tag="ClothDRAFT_2314"
                     /EC_number="1.1.1.23"
                     /inference="protein motif:TFAM:TIGR00069"
                     /note="KEGG: geo:Geob_0689 histidinol dehydrogenase;
                     TIGRFAM: histidinol dehydrogenase;
                     PFAM: histidinol dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="ZP_05430453.1"
                     /db_xref="GI:256005491"
                     /db_xref="InterPro:IPR001692"
                     /translation="MIKIIDLRCGKDSDIFENLASRSQLEYRDVLDRVEEIVANVRRN
                     GDKAVLEYTAMFDKVQLTLGKLRVTEKEIKEAYTKVDPKLVEVIKRSRDNIWNFHEKQ
                     KEKSWFSTEKEGVIVGQLYRPLEVVGVYVPGGTAAYPSSVLMCAVPAKVAGVSKIVMT
                     TPPGKDEKINPAILVAANEAGVDEIYKVGGAQAVAALAFGTETIPKVDKIVGPGNIYV
                     AMAKRTVYGYCDIDMIAGPSEIMVVADETANPVFVAADLLSQAEHDILASSILVTTSE
                     DIAKEVQRELEAQLAVLERKEIAGKSIADYGAIIIVESLKDAATVVNRIAPEHLELCV
                     KDPFAALGDIKNAGAIFLGNYSTEPLGDYFAGPNHVLPTSGTARFFSPLNLSDFMKKS
                     SIISYTRDALQKVKDDVILFAESEGLGAHANAIRVRFQDGQDK"
     misc_feature    complement(17717..18892)
                     /locus_tag="ClothDRAFT_2314"
                     /note="E.C 1.1.1.23. Histidinol dehydrogenase catalyzes
                     the last two steps in the L-histidine biosynthesis
                     pathway, which is conserved in bacteria, archaea, fungi,
                     and plants. These last two steps are (i) the NAD-dependent
                     oxidation of L-histidinol to L-...; Region: Histidinol_dh;
                     cd06572"
                     /db_xref="CDD:119329"
     misc_feature    complement(17687..18880)
                     /locus_tag="ClothDRAFT_2314"
                     /note="Histidinol dehydrogenase [Amino acid transport and
                     metabolism]; Region: HisD; COG0141"
                     /db_xref="CDD:30490"
     misc_feature    complement(order(18191..18193,18326..18331,18335..18343,
                     18404..18406,18410..18415,18494..18496,18557..18559,
                     18581..18586,18590..18592,18812..18814))
                     /locus_tag="ClothDRAFT_2314"
                     /note="NAD binding site; other site"
                     /db_xref="CDD:119329"
     misc_feature    complement(order(17717..17737,17741..17746,17789..17812,
                     17819..17824,17828..17842,17846..17851,17879..17881,
                     17885..17887,17891..17905,17909..17914,17918..17920,
                     17924..17950,17954..17959,17966..17968,17981..17983,
                     18191..18196,18200..18208,18212..18217,18224..18229,
                     18299..18301,18311..18313,18356..18358,18560..18574,
                     18608..18610,18614..18616,18623..18637,18647..18649,
                     18653..18655,18674..18679,18686..18691,18698..18703,
                     18710..18712,18716..18721,18728..18733))
                     /locus_tag="ClothDRAFT_2314"
                     /note="dimerization interface; other site"
                     /db_xref="CDD:119329"
     misc_feature    complement(order(17717..17719,17726..17728,17732..17734,
                     17873..17875,17891..17896,17906..17908,17993..17998,
                     18191..18193,18266..18268,18560..18562,18566..18568))
                     /locus_tag="ClothDRAFT_2314"
                     /note="product binding site; other site"
                     /db_xref="CDD:119329"
     misc_feature    complement(order(17717..17719,17726..17728,17732..17734,
                     17873..17875,17891..17896,17906..17908,17993..17998,
                     18191..18193,18200..18202,18266..18268,18560..18562))
                     /locus_tag="ClothDRAFT_2314"
                     /note="substrate binding site; other site"
                     /db_xref="CDD:119329"
     misc_feature    complement(order(17717..17719,17894..17896,18191..18193,
                     18200..18202))
                     /locus_tag="ClothDRAFT_2314"
                     /note="zinc binding site; other site"
                     /db_xref="CDD:119329"
     misc_feature    complement(17993..17998)
                     /locus_tag="ClothDRAFT_2314"
                     /note="catalytic residues; other site"
                     /db_xref="CDD:119329"
     gene            complement(18985..19626)
                     /locus_tag="ClothDRAFT_2315"
     CDS             complement(18985..19626)
                     /locus_tag="ClothDRAFT_2315"
                     /EC_number="2.4.2.17"
                     /inference="protein motif:TFAM:TIGR00070"
                     /note="KEGG: gbm:Gbem_3706 ATP phosphoribosyltransferase;
                     TIGRFAM: ATP phosphoribosyltransferase;
                     PFAM: ATP phosphoribosyltransferase catalytic region"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="ZP_05430454.1"
                     /db_xref="GI:256005492"
                     /db_xref="InterPro:IPR013820"
                     /translation="MRYLTIALSKGRLTDMSVELFEAIGIDCTELKNSSRKLILTDEK
                     NKIKFFLAKPSDVPTYVEYGAADIGIVGKDTLMEEGRHLYEVLNLGFAACKMVVAGPA
                     ELMGKLDRLTNKRVATKYPRIAREYFEHKRKESIEVIKLNGSVELAPLVGLSEVIVDL
                     VESGRTLKENGLVVLDTIADISARLVVNRVSMKMKSERINPIIDAIRKELEKR"
     misc_feature    complement(18988..19626)
                     /locus_tag="ClothDRAFT_2315"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cl11398"
                     /db_xref="CDD:187020"
     gene            complement(19644..20900)
                     /locus_tag="ClothDRAFT_2316"
     CDS             complement(19644..20900)
                     /locus_tag="ClothDRAFT_2316"
                     /EC_number="6.1.1.21"
                     /inference="protein motif:TFAM:TIGR00443"
                     /note="KEGG: geo:Geob_0845 histidyl-tRNA synthetase 2;
                     TIGRFAM: histidyl-tRNA synthetase 2;
                     PFAM: tRNA synthetase class II (G H P and S)"
                     /codon_start=1
                     /transl_table=11
                     /product="histidyl-tRNA synthetase 2"
                     /protein_id="ZP_05430455.1"
                     /db_xref="GI:256005493"
                     /db_xref="InterPro:IPR002314"
                     /db_xref="InterPro:IPR004517"
                     /db_xref="InterPro:IPR006195"
                     /translation="MAEWKIYTPEGVQDILQNECFFKKNLEDRIRKVFRASGYYEVET
                     PIVEFYDVFSTEENIIPQETMFKFFDQQGRILVLRPDLTIPIARVAATKLKDAAYPLR
                     ISYIGNAFKYNELGGGKQKEFTQAGVEIIGVNTPEADAEVIATAIDAVKATGLENFQI
                     DIGQVEFFKGLMEETGLSEEETEKMRVLIDRKDFLGIEELVEEHNIRDDLKELILDFP
                     KLFGSTDVIDRVEKYPINERSIKALNNLRSIINILDDYGLSKYVSVDLGMVQSLNYYS
                     GTIFRGFTYGVGFPILSGGRYDRLVEKFGKSSPATGFSMGINMVMMALDRQKVEFEKP
                     RVDTLVCYREEGRKTAFQICETLRKQGLAVEVDINGGDFETARNYAALKGIGGILKVL
                     DDENIEIHNLEKGEVSKVTISELLKA"
     misc_feature    complement(19704..20891)
                     /locus_tag="ClothDRAFT_2316"
                     /note="ATP phosphoribosyltransferase regulatory subunit;
                     Provisional; Region: hisZ; PRK12292"
                     /db_xref="CDD:183410"
     misc_feature    complement(19926..20834)
                     /locus_tag="ClothDRAFT_2316"
                     /note="Class II Histidinyl-tRNA synthetase (HisRS)-like
                     catalytic core domain. HisRS is a homodimer. It is
                     responsible for the attachment of histidine to the 3' OH
                     group of ribose of the appropriate tRNA. This domain is
                     primarily responsible for ATP-dependent...; Region:
                     HisRS-like_core; cd00773"
                     /db_xref="CDD:73226"
     misc_feature    complement(order(19962..19967,20016..20018,20469..20471,
                     20478..20480,20490..20492,20514..20516,20535..20540,
                     20622..20627,20634..20639,20652..20654,20658..20660,
                     20694..20699,20760..20780,20793..20795,20829..20831))
                     /locus_tag="ClothDRAFT_2316"
                     /note="dimer interface; other site"
                     /db_xref="CDD:73226"
     misc_feature    complement(20760..20786)
                     /locus_tag="ClothDRAFT_2316"
                     /note="motif 1; other site"
                     /db_xref="CDD:73226"
     misc_feature    complement(order(19944..19946,19953..19955,19962..19964,
                     20016..20018,20031..20033,20076..20081,20085..20087,
                     20091..20093,20514..20516,20526..20528,20532..20534,
                     20541..20543,20562..20564,20568..20570,20652..20654,
                     20658..20660))
                     /locus_tag="ClothDRAFT_2316"
                     /note="active site"
                     /db_xref="CDD:73226"
     misc_feature    complement(20559..20573)
                     /locus_tag="ClothDRAFT_2316"
                     /note="motif 2; other site"
                     /db_xref="CDD:73226"
     misc_feature    complement(order(19944..19946,19953..19967))
                     /locus_tag="ClothDRAFT_2316"
                     /note="motif 3; other site"
                     /db_xref="CDD:73226"
     gene            21419..22954
                     /locus_tag="ClothDRAFT_2317"
     CDS             21419..22954
                     /locus_tag="ClothDRAFT_2317"
                     /inference="protein motif:PFAM:PF00404"
                     /note="PFAM: cellulosome protein dockerin type I;
                     KEGG: scl:sce4860 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulosome protein dockerin type I"
                     /protein_id="ZP_05430456.1"
                     /db_xref="GI:256005494"
                     /db_xref="InterPro:IPR002048"
                     /db_xref="InterPro:IPR002105"
                     /db_xref="InterPro:IPR016160"
                     /translation="MKASKVGQKVILFLVSFSLFISCITISATAANGGKLGDINSDGS
                     INSTDVTLLKRHLLRENILTGTAYSNADTDGDGKITSIDLSYLKRYVLRLISSFPGET
                     SNNLNIPWDWVGIIGTGQSLSVGTTPILSTTQPYNNLKLDLGNLRVPPYDANSSELKL
                     VPLTEPIRSLATGFPSAYPRNLYGETPHSAMANQITAMVKAAGGNDYISVHTVVGESG
                     QGMSVIKKGATDTGNTGRAYAASIFEVTAINRLAKAAGKTYGVGGIILTHGETDCGNP
                     NYENELRQLWSDYNKDIKAITGQTQNIPMFVVQQHSYPSTGTSASTLAQWKAGVDYPG
                     DIICIGPNYQRTYGGDNVHLTSAGYQHLGEKYAQVYYEKVILGKDWKPLQPIKATKNG
                     RTIIVDFHVPVPPLVWDNTLPAPNQNTLTEWRNGKGFEVTANGSRVTINSVEISGNSV
                     IITCASELPAWGVKVGYAFTGGKARPNGTYRWGLLRDSDPFIGRSGVAQPNFCVSFEM
                     PVN"
     sig_peptide     21419..21511
                     /locus_tag="ClothDRAFT_2317"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 0.999) with cleavage site probability 0.939 at
                     residue 31"
     misc_feature    21530..21592
                     /locus_tag="ClothDRAFT_2317"
                     /note="Dockerin type I repeat; Region: Dockerin_1;
                     pfam00404"
                     /db_xref="CDD:144118"
     misc_feature    21632..21694
                     /locus_tag="ClothDRAFT_2317"
                     /note="Dockerin type I repeat; Region: Dockerin_1;
                     pfam00404"
                     /db_xref="CDD:144118"
     gene            complement(23206..24099)
                     /locus_tag="ClothDRAFT_2318"
     CDS             complement(23206..24099)
                     /locus_tag="ClothDRAFT_2318"
                     /inference="protein motif:PFAM:PF03412"
                     /note="PFAM: peptidase C39 bacteriocin processing;
                     KEGG: tau:Tola_3079 peptidase C39 bacteriocin processing"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39 bacteriocin processing"
                     /protein_id="ZP_05430457.1"
                     /db_xref="GI:256005495"
                     /db_xref="InterPro:IPR005074"
                     /translation="MYFNRAIFPAVIIGIILFIIGQRTSRAVSGKPVRILLGFVFILL
                     CIPNFLFGAYYMHFINEPVWYIKFRAIDNIELLSSLTGLFFGFVTFKDESFGKIKLKV
                     FNKYIFVICMLLIIVPFIKPIIRPVSRNSQFQDRWKDGVCLQSTGSTCGPAALATIFN
                     YYGISKSEEEIARAAFSSSSGTENWYLIRYAEKNGLETEVSYKNSLNDVPVPSIIGTY
                     INGRIGHFITILGKEGDHFVVGDSLKGRLLLTEKEFNKYYTFSNFVLHIKKPEDLYSS
                     KMKPGNGETEGNFDTENTDDT"
     misc_feature    complement(23299..23685)
                     /locus_tag="ClothDRAFT_2318"
                     /note="A sub-family of peptidase family C39. Peptidase
                     family C39 mostly contains bacteriocin-processing
                     endopeptidases from bacteria. The cysteine peptidases in
                     family C39 cleave the 'double-glycine' leader peptides
                     from the precursors of various...; Region: Peptidase_C39G;
                     cd02423"
                     /db_xref="CDD:30275"
     misc_feature    complement(order(23377..23379,23425..23427,23650..23652,
                     23668..23670))
                     /locus_tag="ClothDRAFT_2318"
                     /note="putative active site; other site"
                     /db_xref="CDD:30275"
     gene            complement(24269..26026)
                     /locus_tag="ClothDRAFT_2319"
     CDS             complement(24269..26026)
                     /locus_tag="ClothDRAFT_2319"
                     /inference="protein motif:PFAM:PF00395"
                     /note="PFAM: S-layer domain protein;
                     KEGG: hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer domain protein"
                     /protein_id="ZP_05430458.1"
                     /db_xref="GI:256005496"
                     /db_xref="InterPro:IPR001119"
                     /translation="MKRVLSIILVLGIMMLSTAAAAATGYDTVFSDISGHWAKDTIER
                     MANLGIVKGVGNGMFLPDREIKRSEFIVALHKAAEIKINYFKAPDINEFFDDVKNEDW
                     YASTLYDLASLNIVDDREKFRPNDLITREEMVHYLVNTYKYKLNIVLDQIDEKDKCFD
                     DEESIQKQYKESVKYAFKLGFVRGRSNGKFVPKGYSTRAEAMIVLEKLMQALKENIKA
                     EVEVIPSFEKHEDGYKMALTIKNNSKKDVVIQHFSGQKYDFVLLDDKKEELYRWSGDR
                     AFVEILTSTEIPAGKTVEFSEILDAKTYDEISGKAYYFKAVIVGSSEDFEINEDGYYL
                     SLKEEKDNKLEIVPSYKKGEKTFTMKLSIKNTSKKPITINHTSGQKFDFKLLDENKEI
                     IYTWSADKIFIMMETQTVIDPGKTVEFADELDMESFGDIVKKARYLKAYIVGASEDCE
                     IEEDGYEVEITESKENSLVVVPEYEKSQNTFTMKLKLKNTSDGDITINHSSGQKFDFK
                     LLDKNKEILYTWSADKGFIGVLTETVIDAGKTVEFEEKLDMENYKDVIGKAKYLKAYI
                     VGTSEDCDIEKDGYEIEIK"
     sig_peptide     complement(25958..26026)
                     /locus_tag="ClothDRAFT_2319"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 1.000) with cleavage site probability 0.907 at
                     residue 23"
     misc_feature    complement(25814..25939)
                     /locus_tag="ClothDRAFT_2319"
                     /note="S-layer homology domain; Region: SLH; pfam00395"
                     /db_xref="CDD:144111"
     misc_feature    complement(25625..25747)
                     /locus_tag="ClothDRAFT_2319"
                     /note="S-layer homology domain; Region: SLH; pfam00395"
                     /db_xref="CDD:144111"
     misc_feature    complement(25421..25552)
                     /locus_tag="ClothDRAFT_2319"
                     /note="S-layer homology domain; Region: SLH; pfam00395"
                     /db_xref="CDD:144111"
     gene            complement(26172..28397)
                     /locus_tag="ClothDRAFT_2320"
     CDS             complement(26172..28397)
                     /locus_tag="ClothDRAFT_2320"
                     /inference="protein motif:TFAM:TIGR01073"
                     /note="TIGRFAM: ATP-dependent DNA helicase PcrA;
                     PFAM: UvrD/REP helicase;
                     KEGG: gme:Gmet_0089 ATP-dependent DNA helicase PcrA"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase PcrA"
                     /protein_id="ZP_05430459.1"
                     /db_xref="GI:256005497"
                     /db_xref="InterPro:IPR000212"
                     /db_xref="InterPro:IPR000634"
                     /db_xref="InterPro:IPR005751"
                     /db_xref="InterPro:IPR014016"
                     /db_xref="InterPro:IPR014017"
                     /translation="MDLLKDLNKEQREAVLHVDGPLLVLAGAGSGKTKVLTHRIAYLI
                     KEKNVHPASILAITFTNKAAREMRERIDRLVEDVSDSIWVSTFHSMCVRILRRDIEKI
                     DYDKNFVIFDYADQQNVVKDCLKELNLSDKNFPPKSILEMIGRAKDELITPDSYLKMY
                     SGDFRMEKIARVYELYQKKLKQNNALDFDDIIMLTIKLFLDNPEVLNYYQRKFKYILV
                     DEYQDTNTAQYSLVSLLAQGYRNLCVVGDDDQSIYGWRGANIRNILDFEKEFKDAKVI
                     KLEQNYRSTQIILDAANHVIKNNVGRKAKRLWTNNKGGDGIRYLECLNEHEEAYFVAS
                     EIKRLCREQNRSYKDFAVLYRINAMSRVIEDELMREGISYKIFGGLRFYDRKEIKDVI
                     AYLRVIQNPSDNISLKRIINEPKRGIGNATIDTAERLANERGVSIFSIISSAAEIPEL
                     ARASSKLEKFVSLINSLRAQSMVMTASEMIEEVLERTGILEAYRQENTLEAQSRIENI
                     KELLSVAIEFENESEEKSLTDFLAHVSLVSDVDTMDENSEYVALMTLHSAKGLEFPVV
                     FLVGMEEGIFPGYRSMTNESELEEERRLCYVGITRAKENLYMTSTFSRTLFGNTTYNR
                     VSRFVKEIPEELFDFGGDKKKAKDENIGEGTAKKSGTLNKDFNSSKSFNAVSFKPVQR
                     TETSKTELKVGDVVRHKVFGEGIITKREPDGDDFKLEIHFKGKGMKRLLESYANLTKV
                     N"
     misc_feature    complement(26193..28391)
                     /locus_tag="ClothDRAFT_2320"
                     /note="ATP-dependent DNA helicase PcrA; Region: pcrA;
                     TIGR01073"
                     /db_xref="CDD:162191"
     misc_feature    complement(26934..28379)
                     /locus_tag="ClothDRAFT_2320"
                     /note="UvrD/REP helicase; Region: UvrD-helicase; cl14126"
                     /db_xref="CDD:187234"
     misc_feature    complement(26577..>26834)
                     /locus_tag="ClothDRAFT_2320"
                     /note="UvrD/REP helicase; Region: UvrD-helicase; cl14126"
                     /db_xref="CDD:187234"
     gene            complement(28512..29045)
                     /locus_tag="ClothDRAFT_2321"
     CDS             complement(28512..29045)
                     /locus_tag="ClothDRAFT_2321"
                     /inference="protein motif:TFAM:TIGR00741"
                     /note="TIGRFAM: ribosomal subunit interface protein;
                     PFAM: sigma 54 modulation protein/ribosomal protein S30EA;
                     KEGG: gsu:GSU1886 ribosomal subunit interface protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54 modulation protein/ribosomal protein
                     S30EA"
                     /protein_id="ZP_05430460.1"
                     /db_xref="GI:256005498"
                     /db_xref="InterPro:IPR003489"
                     /translation="MRFKVVGKNIVVTEALKEAAVKKVGKLDKYFRRDAEATITMSVQ
                     KNRHIVEVTIPFEGGLLRAEEDSPDMYASIDKVIDSLERQIRRNKTKLEKKVHDGSLR
                     FENIKFDDDEVEEEPKFEVVRTKKFAIKPMTVEEAILQMNLLGHQFFMFSNAETNEAN
                     VVYRRKDGNYGLIEPEF"
     misc_feature    complement(28773..29042)
                     /locus_tag="ClothDRAFT_2321"
                     /note="RaiA ('ribosome-associated inhibitor A', also known
                     as Protein Y (PY), YfiA, and SpotY,  is a stress-response
                     protein that binds the ribosomal subunit interface and
                     arrests translation by interfering with aminoacyl-tRNA
                     binding to the ribosomal A site...; Region: RaiA; cd00552"
                     /db_xref="CDD:29642"
     misc_feature    complement(order(28773..28775,28785..28790,28830..28832,
                     28839..28841,28845..28847,28854..28856,28860..28862,
                     28869..28880,28887..28889,28914..28916,28926..28928,
                     28938..28943,28959..28961,28968..28970,29022..29024,
                     29028..29030,29034..29036))
                     /locus_tag="ClothDRAFT_2321"
                     /note="30S subunit binding site; other site"
                     /db_xref="CDD:29642"
     gene            complement(30320..32137)
                     /locus_tag="ClothDRAFT_2322"
     CDS             complement(30320..32137)
                     /locus_tag="ClothDRAFT_2322"
                     /EC_number="4.1.1.32"
                     /inference="protein motif:PRIAM:4.1.1.32"
                     /note="PFAM: phosphoenolpyruvate carboxykinase (GTP);
                     KEGG: pzu:PHZ_c2232 phosphoenolpyruvate carboxykinase
                     (GTP)"
                     /codon_start=1
                     /transl_table=11
                     /product="Phosphoenolpyruvate carboxykinase (GTP)"
                     /protein_id="ZP_05430461.1"
                     /db_xref="GI:256005499"
                     /db_xref="InterPro:IPR008209"
                     /translation="MTSTNMTKNKKLLDWVKEMAEMCQPDEIYWCDGSEEENERLIKL
                     MVDSGLATPLNPEKRPGCYLFRSDPSDVARVEDRTFIASKTKEDAGPTNNWIDPVELK
                     ATMKELYKGCMKGRTMYVIPFSMGPIGSPISKIGVELTDSPYVVVNMRIMTRIGKAVL
                     DQLGEDGDFVPCLHSVGAPLKEGEKDKGWPCAPIEKKYISHFPEERTIWSYGSGYGGN
                     ALLGKKCFALRIASVMARDEGWLAEHMLILRITDPEGNKTYVTGAFPSACGKTNLAML
                     IPTIPGWKVETIGDDIAWMRFGKDGRLYAINPEAGFFGVAPGTSMDSNPNAMHTIKKN
                     TIFTNVALTDDGDVWWEGIGTEPPAHLIDWQGKDWTPDSGTLAAHPNGRFTAPASQCP
                     VIAPEWEDPEGVPISAILIGGRRPNTIPLVHESFDWNHGVFMGSIMGSEITAAAISNK
                     IGQVRRDPFAMLPFIGYNVNDYLQHWLNMGTKTDPSKLPKIFYVNWFRKDSNGKWLWP
                     GYGENSRVLKWIVERVNGKGKAVKTPIGYMPTVDAIDTTGLDVSKEDMEELLSVNKEQ
                     WLQEVESIKEHYKSYGEKLPKELWAQLEALEQRLKEYNG"
     misc_feature    complement(30350..32104)
                     /locus_tag="ClothDRAFT_2322"
                     /note="Phosphoenolpyruvate carboxykinase (PEPCK), a
                     critical gluconeogenic enzyme, catalyzes the first
                     committed step in the diversion of tricarboxylic acid
                     cycle intermediates toward gluconeogenesis. It catalyzes
                     the reversible decarboxylation and...; Region: PEPCK_GTP;
                     cd00819"
                     /db_xref="CDD:29831"
     misc_feature    complement(30329..32098)
                     /locus_tag="ClothDRAFT_2322"
                     /note="Phosphoenolpyruvate carboxykinase; Region: PEPCK;
                     pfam00821"
                     /db_xref="CDD:144423"
     misc_feature    complement(order(30599..30601,30608..30610,30617..30619,
                     30989..30991,31166..31168,31193..31195,31199..31201,
                     31265..31270,31322..31342,31406..31408,31466..31471,
                     31487..31489,31493..31495,31916..31918))
                     /locus_tag="ClothDRAFT_2322"
                     /note="active site"
                     /db_xref="CDD:29831"
     misc_feature    complement(order(30989..30991,31199..31201,31466..31471,
                     31487..31489,31493..31495,31916..31918))
                     /locus_tag="ClothDRAFT_2322"
                     /note="substrate-binding site; other site"
                     /db_xref="CDD:29831"
     misc_feature    complement(order(31199..31201,31265..31270,31325..31327,
                     31406..31408,31466..31468))
                     /locus_tag="ClothDRAFT_2322"
                     /note="metal-binding site"
                     /db_xref="CDD:29831"
     misc_feature    complement(order(30599..30601,30608..30610,30617..30619,
                     30647..30652,30896..30898,31331..31333,31337..31339))
                     /locus_tag="ClothDRAFT_2322"
                     /note="GTP binding site; other site"
                     /db_xref="CDD:29831"
     gene            32535..33236
                     /locus_tag="ClothDRAFT_2323"
     CDS             32535..33236
                     /locus_tag="ClothDRAFT_2323"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: maq:Maqu_2145 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430462.1"
                     /db_xref="GI:256005500"
                     /translation="MKKNVVLILGIVFTAAGLIPILIGVTFFLSHYNFISNAARTTAV
                     VTDIKSYRDFDGDKHYEVVIKYSVEGEEYYEIIAHSPLMYVGREITVYYDPNKPRHVK
                     TMGFVFDDLFLVGIGLVFFIIGISFTASQFKKFRLRKRLLETGRTVYADISEITLNTS
                     YTVNSKHPYVITCKWKDPDTGLFYFFTSDNIWFDPEPIIHEKGITSLPVYIDPENPKN
                     YFVSVKDIEMFVANV"
     sig_peptide     32535..32651
                     /locus_tag="ClothDRAFT_2323"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 0.824) with cleavage site probability 0.609 at
                     residue 39"
     misc_feature    32544..>32837
                     /locus_tag="ClothDRAFT_2323"
                     /note="Protein of unknown function (DUF3592); Region:
                     DUF3592; pfam12158"
                     /db_xref="CDD:152593"
     gene            33540..35240
                     /locus_tag="ClothDRAFT_2324"
     CDS             33540..35240
                     /locus_tag="ClothDRAFT_2324"
                     /inference="protein motif:PFAM:PF00150"
                     /note="PFAM: glycoside hydrolase family 5; cellulosome
                     protein dockerin type I;
                     KEGG: azc:AZC_1301 endoglucanase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5"
                     /protein_id="ZP_05430463.1"
                     /db_xref="GI:256005501"
                     /db_xref="InterPro:IPR001547"
                     /db_xref="InterPro:IPR002048"
                     /db_xref="InterPro:IPR002105"
                     /db_xref="InterPro:IPR005479"
                     /translation="MKKAKAIFSLVVALMVLAIFCFAQNTGSTATTAAAAVDSNNDDW
                     LHCKGNKIYDMYGNEVWLTGANWFGFNCSENCFHGAWYDVKTILTSIADRGINLLRIP
                     ISTELLYSWMIGKPNPVSSVTASNNPPYHVVNPDFYDPETDDVKNSMEIFDIIMGYCK
                     ELGIKVMIDIHSPDANNSGHNYELWYGKETSTCGVVTTKMWIDTLVWLADKYKNDDTI
                     IAFDLKNEPHGKRGYTAEVPKLLAKWDNSTDENNWKYAAETCAKAILEVNPKVLIVIE
                     GVEQYPKTEKGYTYDTPDIWGATGDASPWYSAWWGGNLRGVKDYPIDLGPLNSQIVYS
                     PHDYGPSVYAQPWFEKDFTMQTLLDDYWYDTWAYIHDQGIAPILIGEWGGHMDGGKNQ
                     KWMTLLRDYIVQNRIHHTFWCINPNSGDTGGLVGNDWSTWDEAKYALLKPALWQTKDG
                     KFIGLDHKIPLGSKGISLGEYYGTPQASDPPATPTATPTKPAASSTPSFIYGDINSDG
                     NVNSTDLGILKRIIVKNPPASANMDAADVNADGKVNSTDYTVLKRYLLRSIDKLPHTT
                     "
     sig_peptide     33540..33611
                     /locus_tag="ClothDRAFT_2324"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 1.000) with cleavage site probability 0.548 at
                     residue 24"
     misc_feature    33690..34805
                     /locus_tag="ClothDRAFT_2324"
                     /note="Cellulase (glycosyl hydrolase family 5); Region:
                     Cellulase; cl12144"
                     /db_xref="CDD:159804"
     misc_feature    35145..35207
                     /locus_tag="ClothDRAFT_2324"
                     /note="Dockerin type I repeat; Region: Dockerin_1;
                     pfam00404"
                     /db_xref="CDD:144118"
     gene            complement(35323..35835)
                     /locus_tag="ClothDRAFT_2325"
     CDS             complement(35323..35835)
                     /locus_tag="ClothDRAFT_2325"
                     /inference="protein motif:PFAM:PF07739"
                     /note="PFAM: TipAS antibiotic-recognition domain protein;
                     KEGG: mxa:MXAN_5120 transcriptional activator TipA"
                     /codon_start=1
                     /transl_table=11
                     /product="TipAS antibiotic-recognition domain protein"
                     /protein_id="ZP_05430464.1"
                     /db_xref="GI:256005502"
                     /db_xref="InterPro:IPR012925"
                     /translation="MFIRKREQLDLLIANVEKTIAAAERRAEMTDKEKFEGFKQKMIE
                     ENERKYGEEIREKYGDEEVDKSYRKLKNMTKEQYEEAERLSAELKNLLKQAFATGDPA
                     GELAQKAADLHRQWLCCFWESYSKEAHAGLAKMYVEDERFAAYYDKDQPGTAEFLRDA
                     ILIYTGMKEE"
     misc_feature    complement(35341..35703)
                     /locus_tag="ClothDRAFT_2325"
                     /note="TipAS antibiotic-recognition domain; Region: TipAS;
                     pfam07739"
                     /db_xref="CDD:149030"
     gene            complement(35875..37176)
                     /locus_tag="ClothDRAFT_2326"
     CDS             complement(35875..37176)
                     /locus_tag="ClothDRAFT_2326"
                     /inference="protein motif:PFAM:PF01595"
                     /note="PFAM: protein of unknown function DUF21; CBS domain
                     containing protein; transporter-associated region;
                     SMART: CBS domain containing protein;
                     KEGG: gme:Gmet_1153 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="protein of unknown function DUF21"
                     /protein_id="ZP_05430465.1"
                     /db_xref="GI:256005503"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="InterPro:IPR002550"
                     /db_xref="InterPro:IPR005170"
                     /translation="MFVEILVLILLIVLNGFFAASEIALISLNDNKLRLMGNEKSKKK
                     IEILKKLLSEPGRFLATIQIGITLGGTLSSAFASESFSDRLAGLIKQTGVPVPDAVLK
                     TLSMIFVSVILSYFSLVIGELVPKRLAMKKEEAISMFAARPLYILSVVTYPAVKLLNA
                     STNLIVRLFGIDPNADEEEVTEEEIRMMVDVGEEKGTIQENEKEMINNIFDFDNKTVM
                     DIMTHRTDIVALPVDASLDEVISLFNEEKYTRIPVYEESIDNIVGILHVKDLIKYIGV
                     GSDTADFDLRKIIRKPYNVPWSKKADELFSELQKNKVHMAIIIDEYGGTAGIVTVEDL
                     VEEIVGNIFDEYDEEEKDFEKLDESTYIFSGTAGLDVLNEWADAQLPEDEYDTLSGFI
                     ISQLGRIPEYDEKPEIEFNGLLFKVEEVSEKRIEKIKVCRA"
     misc_feature    complement(35887..37134)
                     /locus_tag="ClothDRAFT_2326"
                     /note="Hemolysins and related proteins containing CBS
                     domains [General function prediction only]; Region: TlyC;
                     COG1253"
                     /db_xref="CDD:31445"
     misc_feature    complement(36571..37134)
                     /locus_tag="ClothDRAFT_2326"
                     /note="Domain of unknown function DUF21; Region: DUF21;
                     pfam01595"
                     /db_xref="CDD:144983"
     misc_feature    complement(36166..36504)
                     /locus_tag="ClothDRAFT_2326"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domains associated
                     with the CorC_HlyC domain. CorC_HlyC is a transporter
                     associated domain. This small domain is found in Na+/H+
                     antiporters, in proteins involved in...; Region:
                     CBS_pair_CorC_HlyC_assoc; cd04590"
                     /db_xref="CDD:73090"
     misc_feature    complement(35881..36099)
                     /locus_tag="ClothDRAFT_2326"
                     /note="Transporter associated domain; Region: CorC_HlyC;
                     pfam03471"
                     /db_xref="CDD:146225"
     gene            complement(37707..38693)
                     /locus_tag="ClothDRAFT_2327"
     CDS             complement(37707..38693)
                     /locus_tag="ClothDRAFT_2327"
                     /inference="protein motif:PFAM:PF01408"
                     /note="PFAM: oxidoreductase domain protein; homoserine
                     dehydrogenase NAD-binding; Oxidoreductase domain;
                     KEGG: MGC82109 protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain protein"
                     /protein_id="ZP_05430466.1"
                     /db_xref="GI:256005504"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="InterPro:IPR005106"
                     /translation="MADKIRWGILGCGRIARTFAESLQHVPDAKLAAVASKTPGRAAE
                     FAKIFNAERYYEDYQELVKDESLDVIYVATTHNFHYEHALLCLENKKAVLCEKPFTVN
                     SKQAEDLIKVARRNKVFLMEAMWTRFLPCIVELNRLLSQNIIGDIGFLRADFGNSTKG
                     RDVPKYYFDPNLAGGALLDLGVYPVSFARLVFKKSPVGIKTFGYIADSKVDVHAAYMF
                     EFGFGKVAMLSSSYSVDMPHDAVICGTEGYIKVPDFFHPTQFSIHLNGREEKVVRIPF
                     VSNGLNYQVQEVNKCLKEGKLESDIMPLNESLEVMKILDVLRAKWGLKYPME"
     misc_feature    complement(37710..38684)
                     /locus_tag="ClothDRAFT_2327"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:31017"
     misc_feature    complement(38322..38681)
                     /locus_tag="ClothDRAFT_2327"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:186874"
     misc_feature    complement(37995..38282)
                     /locus_tag="ClothDRAFT_2327"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; cl11611"
                     /db_xref="CDD:159579"
     gene            complement(38898..39992)
                     /locus_tag="ClothDRAFT_2328"
     CDS             complement(38898..39992)
                     /locus_tag="ClothDRAFT_2328"
                     /EC_number="3.1.1.61"
                     /inference="protein motif:PRIAM:3.1.1.61"
                     /note="KEGG: aha:AHA_1386 chemotaxis-specific
                     methylesterase;
                     PFAM: CheB methylesterase; response regulator receiver;
                     SMART: response regulator receiver"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver modulated CheB
                     methylesterase"
                     /protein_id="ZP_05430467.1"
                     /db_xref="GI:256005505"
                     /db_xref="InterPro:IPR000673"
                     /db_xref="InterPro:IPR001789"
                     /translation="MQKYGVLVVDDSSFMRRCISLIIEKDPQLFIIGIARNGIEAIEK
                     VQRLKPDIVTMDVEMPEMDGMTALKEIMRVCPVPVIVLSNQTDKDPETTFQALELGAA
                     DFYLKNALLEENVKPEIIREFLDRLKAIAQKARKCGKKEIKQKTDSEKVSEILDNILS
                     KSEDLIKTKTGAADLLIIGCSTGGPSALQSILPRFPKDTHVPIVVLQHMPPGFTKPLA
                     ERFDAICNLRVKEAEDGDIVEAGNIYIAPAGYQTFFDKKANGVIALRVKDCPSVKTLY
                     KPSINVTLDSAAPIYRERLLSVILTGMGNDGLVGCETVKKYNGKVIVEAEETCVVYGM
                     PKVVYEAGLADIQVPLSDIFHEIMLCIGNK"
     misc_feature    complement(38919..39992)
                     /locus_tag="ClothDRAFT_2328"
                     /note="chemotaxis-specific methylesterase; Provisional;
                     Region: PRK00742"
                     /db_xref="CDD:179106"
     misc_feature    complement(39600..39974)
                     /locus_tag="ClothDRAFT_2328"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems...; Region: REC;
                     cd00156"
                     /db_xref="CDD:29071"
     misc_feature    complement(order(39642..39647,39681..39683,39744..39746,
                     39801..39803,39825..39827,39960..39965))
                     /locus_tag="ClothDRAFT_2328"
                     /note="active site"
                     /db_xref="CDD:29071"
     misc_feature    complement(39825..39827)
                     /locus_tag="ClothDRAFT_2328"
                     /note="phosphorylation site"
                     /db_xref="CDD:29071"
     misc_feature    complement(order(39801..39809,39813..39818))
                     /locus_tag="ClothDRAFT_2328"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:29071"
     misc_feature    complement(39639..39647)
                     /locus_tag="ClothDRAFT_2328"
                     /note="dimerization interface; other site"
                     /db_xref="CDD:29071"
     misc_feature    complement(38919..39470)
                     /locus_tag="ClothDRAFT_2328"
                     /note="CheB methylesterase; Region: CheB_methylest;
                     pfam01339"
                     /db_xref="CDD:144802"
     gene            complement(39971..40804)
                     /locus_tag="ClothDRAFT_2329"
     CDS             complement(39971..40804)
                     /locus_tag="ClothDRAFT_2329"
                     /EC_number="2.1.1.80"
                     /inference="protein motif:PRIAM:2.1.1.80"
                     /note="KEGG: gsu:GSU2215 chemotaxis protein
                     methyltransferase CheR;
                     PFAM: MCP methyltransferase CheR-type;
                     SMART: MCP methyltransferase CheR-type"
                     /codon_start=1
                     /transl_table=11
                     /product="MCP methyltransferase, CheR-type"
                     /protein_id="ZP_05430468.1"
                     /db_xref="GI:256005506"
                     /db_xref="InterPro:IPR000780"
                     /translation="MDTFGLIQLAELIYEYCGIDFFKNLSSLESKISDRLKELGLSCW
                     EYGGYLRVEPKEWDKLIELITVNETYFFREENLLEEFQRVILPKYQGRTPDNPLRIWS
                     AACSSGEEPYTLAILIEESGLFEAGAVEIIGSDIDKKVLEKARKGLYNKKSFSFRTMP
                     KEILEKYFVSFGDEYRVKDSIRAMVDFRRLNLLDENIAEMIGEVDIIFCRNVLIYFDA
                     KAINRVVDSLYKVLKVGGYLFLGHAETITGMNTGFETIYAPSTFYYRKGEKYPCRSMG
                     Y"
     misc_feature    complement(40007..40780)
                     /locus_tag="ClothDRAFT_2329"
                     /note="Methylase of chemotaxis methyl-accepting proteins
                     [Cell motility and secretion / Signal transduction
                     mechanisms]; Region: CheR; COG1352"
                     /db_xref="CDD:31543"
     misc_feature    complement(40016..40606)
                     /locus_tag="ClothDRAFT_2329"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy)...; Region:
                     AdoMet_MTases; cl12011"
                     /db_xref="CDD:187159"
     gene            complement(40917..45341)
                     /locus_tag="ClothDRAFT_2330"
     CDS             complement(40917..45341)
                     /locus_tag="ClothDRAFT_2330"
                     /inference="protein motif:PFAM:PF00015"
                     /note="PFAM: chemotaxis sensory transducer;
                     SMART: chemotaxis sensory transducer;
                     KEGG: mxa:MXAN_6962 methyl-accepting chemotaxis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis sensory transducer"
                     /protein_id="ZP_05430469.1"
                     /db_xref="GI:256005507"
                     /db_xref="InterPro:IPR004089"
                     /db_xref="InterPro:IPR004090"
                     /translation="MGFRRHKAVKLKNSELSQKIYETVSSAKKLDEKLKDLSGITEQV
                     AKGASEQSSAVDSTNSMAERLSQSINGVVKNTEKLKELAGESKKSLESMIGTIKLVAG
                     NSESTAKSVEEISSSIEQMGKSIKGVAGNAESLTGSAEEISSAIQKIVGSIEQVAGNA
                     ESTASSVEQISSSIEQMSKSIKGVAGNAESLTGSAREATAAVQEMAASIQQVAGNSEN
                     TASSIERISFSIEQMGRSINGVAVNAESLSNSAEEATNAIHSMVSSIQQVAGNAESTA
                     SSIEQISSSIEQMGKSIKGVAGNAESTSGSAQEASAAIQEIVASIQQVAGNAESTASS
                     IEQISSSIEQMGKSVKGVAGNAESLKGSADEASAAIQEIVASIQQVAGNAESTASSVE
                     QISSSIEQMSKSIKSVAGNAESLSGSAEEASAAVHEIISSIQQVAGNSESTAKSVEEI
                     AASIEKMGRSIQGVAGNAESLKGSADESSAAIQEIVASIQQVAGNAESTASSVEQISS
                     SIEQMGKSIKGVAGNAESLKGSADESAAAIQEIVASIQQVAGNAESTASSVEQISSSI
                     EQMGRSIEGVAGNAESLKASADEASAAIQEIVASIQQVAGNAESTAKSVEEISSSIEE
                     MGKSIQGVAGNAEQLQKSANETSKVVENMAASISQVAQNAQNVNELSEKVRSDAIDGQ
                     KAVADTLVAIKDISEVIHRAEDVINGLGKSSEKIGSIIEVIDDIAEQTNLLALNAAIE
                     AARAGEHGKGFAVVADEVRKLAERTATATKEISELIKGIQGETSQAIKAIEVGTQKVE
                     HGSKLSDEAGKAIEKIVEGIENVNVEIRQITAATEEQNKGSMKIIDAVNMVTNQAAQV
                     TQATKEQAASVENIVRGVANAREQVRQVTVAVKEQAKQGQNIITAVENVTNQAAQVTQ
                     ATKEQTKGVEEIIKGVANAREQVRQVTLAVKEQAKQGQNIVQSIENVTQQTAQVAAAV
                     KEQTAGVEEIIKGVANAREQIRQVTAAMKEQAKQSQNIVVAVENVTKQAAEVTQATKE
                     QAKDIEDIIRGIENAREQMRQVTLAVKEQANHGQNIVVAVENVTKQAAQVTDVTKEQA
                     KGVEDIVKGIENSREQVRQITEAVKEQAKQGQNIVVAVENVNRQAAQVAQAAKEQTQG
                     VEEIIKGVLNAREQVRQITAAVKEQAQQGQNIVTAVENVTNQVSQVTQAAKEQAQGVE
                     QIIKGVINAREQVKQITTAVKEEALQGQIVIRAVENVTNQAAQVTQAVKEQAAGVEEI
                     IKSVADAREQVRQITAAVKEQAKQGQDITASVQNVSEQAALVTNAVKEQTQGIEDIIR
                     GIENAREQMRQVTTTVKEQAKQGQNIVTAVENVANQAAQITNVTKEQAHGVEDIIKSV
                     ANAREQVKQISAAMKEQAVNADKVIGNVEGVTVQANEVADAAKVQANEVEQLAKYTSE
                     IDRVINLNIKDVERTCAVAKELAEYSEEIIGALQELSK"
     misc_feature    complement(44535..45194)
                     /locus_tag="ClothDRAFT_2330"
                     /note="Methyl-accepting chemotaxis-like domains
                     (chemotaxis sensory transducer); Region: MA; smart00283"
                     /db_xref="CDD:128579"
     misc_feature    complement(42687..43463)
                     /locus_tag="ClothDRAFT_2330"
                     /note="Methyl-accepting chemotaxis-like domains
                     (chemotaxis sensory transducer); Region: MA; smart00283"
                     /db_xref="CDD:128579"
     misc_feature    complement(42675..43262)
                     /locus_tag="ClothDRAFT_2330"
                     /note="Taxis toward Aspartate and Related amino acids and
                     Homologs (TarH). The Tar chemoreceptor of Escherichia coli
                     mediates attractant responses to aspartate, maltose, and
                     phenol, repellent responses to Ni2+ and Co2+, and
                     thermoresponses.  These...; Region: TarH; cl00144"
                     /db_xref="CDD:153541"
     misc_feature    complement(<41988..>42776)
                     /locus_tag="ClothDRAFT_2330"
                     /note="chromosome segregation protein SMC, common
                     bacterial type; Region: SMC_prok_B; TIGR02168"
                     /db_xref="CDD:162739"
     misc_feature    complement(41046..>41906)
                     /locus_tag="ClothDRAFT_2330"
                     /note="chromosome segregation protein SMC, common
                     bacterial type; Region: SMC_prok_B; TIGR02168"
                     /db_xref="CDD:162739"
     gene            complement(45375..47183)
                     /locus_tag="ClothDRAFT_2331"
     CDS             complement(45375..47183)
                     /locus_tag="ClothDRAFT_2331"
                     /inference="protein motif:PFAM:PF01584"
                     /note="PFAM: CheW domain protein; Signal transducing
                     histidine kinase homodimeric; Hpt domain protein;
                     ATP-binding region ATPase domain protein;
                     SMART: CheW domain protein; ATP-binding region ATPase
                     domain protein; Hpt domain protein;
                     KEGG: gme:Gmet_3266 CheA signal transduction histidine
                     kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="CheA signal transduction histidine kinase"
                     /protein_id="ZP_05430470.1"
                     /db_xref="GI:256005508"
                     /db_xref="InterPro:IPR002545"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR004105"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="InterPro:IPR008207"
                     /translation="MANISESPEMLEALIREVEEQLQLLKKDIAKLEQNYKATQKAEE
                     LLSIAHPLKGSFAAVDFEKIKTLIHEMENILDKIRRGLVEISEPIIVLLFESLDYLKM
                     LKQGLDSDANNIKAENAIDIEITSVISKLKEILSQSKPNDNNSDTAENAEVEQKNQTI
                     FMLDEKQQERVNQAPDHKTEGEGKKVVHTVRVDIDHLERMMELVGELVIEQIRIAQIS
                     NNLYNQYPFDETVDELIGISNRIPVLINELQDRIMKTRMISVQQLFSRFPGMVRDLSL
                     SLNKEIDLVLEGGETEIDRTIMEEISDPLIHLIRNAIIYGIENQEIRKKLGKPEKGKL
                     RIAALPEDSNVIITVEDDGAGIDVQKIKQSAIEKMVITEQEADNMTEQQLINLIFHAD
                     FSASQNASDVSDYRVRMDIVRNHIERLNGIIDVETCPGRGTKFIIKLPIKLPLTLAIL
                     KGLLVKISNETYALPMDNVVEIVRKPKNEIESINGQAVAVIRDRAIPLVWLHDYFGVP
                     RDEERKNMLIVLVGIAEKRFGLVVDELIGNQEVVVTNLGSYIGKVEGISGATILGDRS
                     VACILDVVGVANIVNNRQASKINGEYLQINDEELTQ"
     misc_feature    complement(46881..47159)
                     /locus_tag="ClothDRAFT_2331"
                     /note="Histidine Phosphotransfer domain, involved in
                     signalling through a two part component systems in which
                     an autophosphorylating histidine protein kinase serves as
                     a phosphoryl donor to a response regulator protein; the
                     response regulator protein is...; Region: HPT; cd00088"
                     /db_xref="CDD:28972"
     misc_feature    complement(order(46968..46970,46977..46979,47022..47027,
                     47034..47036))
                     /locus_tag="ClothDRAFT_2331"
                     /note="putative binding surface; other site"
                     /db_xref="CDD:28972"
     misc_feature    complement(47034..47036)
                     /locus_tag="ClothDRAFT_2331"
                     /note="active site"
                     /db_xref="CDD:28972"
     misc_feature    complement(46419..46622)
                     /locus_tag="ClothDRAFT_2331"
                     /note="Signal transducing histidine kinase, homodimeric
                     domain; Region: H-kinase_dim; pfam02895"
                     /db_xref="CDD:145841"
     misc_feature    complement(45888..46277)
                     /locus_tag="ClothDRAFT_2331"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cl00075"
                     /db_xref="CDD:185789"
     misc_feature    complement(45465..45830)
                     /locus_tag="ClothDRAFT_2331"
                     /note="CheA regulatory domain; CheA is a histidine protein
                     kinase present in bacteria and archea. Activated by the
                     chemotaxis receptor a histidine phosphoryl group from CheA
                     is passed directly to an aspartate in the response
                     regulator CheY. This signalling...; Region: CheA_reg;
                     cd00731"
                     /db_xref="CDD:29681"
     gene            complement(47199..47624)
                     /locus_tag="ClothDRAFT_2332"
     CDS             complement(47199..47624)
                     /locus_tag="ClothDRAFT_2332"
                     /inference="protein motif:PFAM:PF01584"
                     /note="PFAM: CheW domain protein;
                     SMART: CheW domain protein;
                     KEGG: dds:Ddes_1022 CheW protein"
                     /codon_start=1
                     /transl_table=11
                     /product="CheW protein"
                     /protein_id="ZP_05430471.1"
                     /db_xref="GI:256005509"
                     /db_xref="InterPro:IPR002545"
                     /translation="MNELLTSLYVACELVNEKYALKISDVYEIIKMQNITPIPNSQPF
                     LEGVINLRGKIIPVVNLHKRLGLTNYTPTKKTRIVVVKSRDEMIGVVVDKVNHVIRFS
                     DIQPPPEMIAGIDGSYFEGIGITDEGVVSILKIDSVLYE"
     misc_feature    complement(47202..47597)
                     /locus_tag="ClothDRAFT_2332"
                     /note="CheW, a small regulator protein, unique to the
                     chemotaxis signalling in prokaryotes and archea. CheW
                     interacts with the histidine kinase CheA, most likely with
                     the related regulatory domain of CheA. CheW is proposed to
                     form signalling arrays together...; Region: CheW; cd00732"
                     /db_xref="CDD:29682"
     misc_feature    complement(order(47202..47219,47370..47372,47376..47378,
                     47460..47477))
                     /locus_tag="ClothDRAFT_2332"
                     /note="putative CheA interaction surface; other site"
                     /db_xref="CDD:29682"
ORIGIN      
        1 cgatattttc aatttgtcaa cactttttta aaatttttta tctaaatttt aaatcccttt
       61 aatttggcgt cgctcatcgg cgacggctct aataatataa caccttaagc aaattgtttc
      121 aactcccggg acagttattt aacataatta tatcaattta ttagttaaat tcttgattat
      181 tctataaaat tttaaacaat atcggctgtt ttctcgatgt atctttctga ttttacaacc
      241 acattgtaca attatacatt attattgttg tcgaaaccga atattttata caactccaaa
      301 gccaaccttt tatatcaaaa tcaaatatcc ttacaattta cataatatta tttaaggctt
      361 ttaaatacta ttaccttgtt tcctttctta ttaagtctta tcctgtcgca caaatttttc
      421 acaatcagga ttccccaccc gttttcttta agatcgcata catccgtaac ctcctcgggg
      481 atttcttcct ttgcgcatac gcaatccaag tcgtagccct caccttcgtc ctccactata
      541 agatagacat gattatcagc cgttataccc acactgactt caaccgactt tgacgcatct
      601 tctttattac cgtgttttat tgcattttgc agaagttcat tcaatataac tttgatttca
      661 aacaggacat cttcacttac atcacttgag tcggataaga atttcattat atctttgacc
      721 aaaaaacaaa tattttcctt ttgacttgac actttcgagt tataagtttt caatactttc
      781 acttaactta tctcccttaa aataatatct actccaatta taatattacc catcatacta
      841 ttgtcgtaaa cattgcctta aacttcccct atgctgaaac cctcatgtta cgcatcaaac
      901 aaacttcatg caaaaagttg ctttgtttat aaatcagctt tgacggatct attttgccag
      961 cattctcctg aatttttcca gtacctttct ttcaagcctg gaaatataca tctgcgatac
     1021 gcccatcttt tgggcaatgt ctttctgagt cttgttgtca aaatacctca tgctgataaa
     1081 ttctttctca acatcgctga atttatcaag actcttttca agaaaatccc tgttctcaat
     1141 tctttcgaaa gtggaatcct gatcaccgat aacttcatgg agctccaact catcgttggc
     1201 atacacattc tgactgaagg actggatatt ataagcgttg taggattcaa taatttcaac
     1261 aacgctttct tcactgatat ttaaatgccg ggcaagctca tctatcctcg gaggcctttt
     1321 taattcctga gtcaatgact ccctggcatg gttaatcttc tgataaacct catatattct
     1381 tctgggaatt ctgataacgg aacccttgtc cctgaaatat ctttttattt cgccgataat
     1441 agtgggtgtt gcaaaactta taaatttaac acccttgtcg ggatcaaatc tctccaccgc
     1501 tttaatcaag gcaatggaaa ccacctgata aatgtcttca taatcaatgc ctctgtttaa
     1561 aaattttttg gcaagtatgt ccgaaagata aagatatttg cttacaattt tgtttcttac
     1621 ctcaacactt tttgtctctt tatattctct aaacaactca tcgctgtcat ttacaacatt
     1681 gttattgttt actgcatcgt ccatcatgac tatctattcc cctcaagcac ttttgacatg
     1741 gatattatcc tgtttgattt gtcacacaat accacattgt ccatcaatgc agttattatg
     1801 cttattgcca gaccgtcttt ctcctcgtca aatatacatt ttatagaagg atcgtcacaa
     1861 acaaactcca catttaaagt attttccgaa acaccatata taatagtgta gttgtccgta
     1921 attttactgc ccatacttac tattttactg caaacttcag atatagcaac ttttatgtcc
     1981 tcaatggttt caatgtcaaa tcctattcga ttacacacac ctgaagcaac cagtcttgca
     2041 acactgacat attcagcttt aaacggcaga gtgagctcaa tcttgtcaca aacagaattc
     2101 atttttccac ctcactattc aataacaaaa accttatcca ggccggttat aataaacagc
     2161 tttttaatat tgtccttgag gctggttata ataatttttt tcccatattg cttggttttt
     2221 ttgagagcac cgacaaaaat gccaagccct gtactgtcaa tataattcag ctccttgcaa
     2281 tctattatca aatcagtctg attattgtca actatactgt aaagtttctc tttaagctcc
     2341 tgggaagtgt aaatgtccac ctctccgaac aaactcaatt taacggaatc atctactttt
     2401 tcttctacaa accttaaacc ctctgacata aaaaattcct ccttccttac tgacctttta
     2461 acaacaatga caccggccgg tttttcaagc ctcagcttat ttaaatttat ataatattat
     2521 acactttgta tcatatatat agcaacttta taggattttt tcccaacaaa agcaccaaat
     2581 ataaaatata agtgaaagct aaatttacaa gtccaatatt taaaattaaa caaaataaat
     2641 attaaatgaa aataaaaata aaatattaaa taaaataaca gcttacattt aatgtaaact
     2701 gttattttaa catatttata atatttttat aaattatata ttaacttaaa ttaattaata
     2761 ttacaagaca cattaaatta cttacggatt tctaaaatct taaacttaat aacgccgtca
     2821 ggtaccgtaa cttcaacaat atctcctatc ttaccaccga taagagcctt tcccacagga
     2881 gactcattgg aaattttgta ctgcgacggg tctgcttcgg tagaaccaac tatataatat
     2941 tccacctctt cgtcaaactc catgtcaaga actttaactt ttgaacctat gcttactaca
     3001 tccgtctgta tatcttcttc atctattact ttggcatttt ttaacatatt ttcaagttga
     3061 aatattcttc cttcgatata agcttgttca ttcttagctt catcatattc ggaattttca
     3121 gatatatcac caaatgaaag agcttgcttg attctctcag ctacctctct tctcttcaca
     3181 gtctttaaat tctcaagttc ttgttccaac ttttgcaatc cttcatatgt cagaacaact
     3241 tctttatttg ttgccattcg aggtctctcc tttacttaga atttcgtgtt gataatatat
     3301 gcatttcctt cttatttatt ctaaagttga agtctttgaa ataaacggca ccgaaatggt
     3361 ataaccacgc cttaggctat gccatggaac cacgaacata aaaatttctt cacccactgg
     3421 tacaaatgaa atggaaccta gcaatcagag tcgtctgata ttacaaatcc gtaccggcaa
     3481 taaatttaca aacacgaaat attctatatc aatttttatt cattatagac cactaatata
     3541 atattgtcaa taacctgcag gcaaaaaagt ttttcataac acaaatcagg aaataaccgg
     3601 aataaagcca aatccgtccc tctcaaactg ccttgcaagc ttttctaata cagcataatc
     3661 aagattattg tttatggtgc atgttccaat ttcaagcctg tttaataaaa taatctcggc
     3721 aagttcaatt ctcttataaa atttataaac gtcttttccc aacttttctt caaattttcc
     3781 cggcaaaatt acatcaacac tgtttataat atcggtaaat tttattttgt ccgtattaat
     3841 acttccataa tttacaacag gctcattgaa tttcatttta ccaggaatat caaaatcacc
     3901 taaatccgca agatttatga ccgcttcggc atctttcatg ccgcccgcca gattgtccgt
     3961 tacccgcacc gccaggcctg tttcttcgaa aatattatcg gtcatatttt caattgactc
     4021 tttctcgtga gttattatcg tcaaaaattt taaaatactt gataaaatct tgatgtatga
     4081 atgcaaaaaa gtatagtcgt ttccatgaat gattgctaca tcaagttccc ttatatcttt
     4141 accctttttt tctgaaatca actttaaaat atttaccagt agtgctttat agagaaaacg
     4201 tccaaaaaaa ggatctttaa cacaaaagtc aatatccaac ttgtcagggg cacagtgagg
     4261 aaaatagcat ttttcaatag aataatccag gcacagtctt tttataattt tcttcagcct
     4321 tcttatttta aaacgtcccg gtctttcaag ttccgacgcc ttatacggta atctcactgt
     4381 aaaaacatta aatccgtcat aaagctccgc tttctttacc gcatcatcgg aaagctttgt
     4441 actaaaaaaa cttcttaaca cattcaatat tcttttaatc agatcccctt tttttgcctt
     4501 ccttcccgtc atagaacagt atcaatccta tattggtcat ttaacaccac ttgctttctt
     4561 ttttgcaggt tttaatacca tcctatttga gagggaagac aaatattcat gttaatcagg
     4621 gaaatttata ctgattgttc cggttttgtt caagccattc ctgatagctt tctatttcct
     4681 tgagattttt gttcaacaca tcccatatat cctcggacac aaaataaatg ctccatgcac
     4741 atgtacccgc aagtctgtat ttatgcacca gagaagtcct taaattgatt gagttggcat
     4801 cctcaagcca aagtctgtaa tttgtattgt ccttggtgta ttctgcgtag aactgtccgc
     4861 tttcctcatc ccattctacc tttgcattgt tttctataat caggtttttt gcctgcttca
     4921 ttgtaagagc gctgctggtc agcttctttt taccggattc atcaaccgtc tctttccaca
     4981 gccgggtata aaaaggaatt cccaaaagca gtttttccct tggtactcct tcctgttcaa
     5041 ggactctttt tactattttc tcctgccagc tcacctgtgc cactgagcct gccacaggac
     5101 ttgtactcca gtgctggtcg taggacatat acattatata atcaacagcc tcgctcaatg
     5161 cctttttgtc ataacattgt atatcgttga catccaccga taccacaagt ccctgttccc
     5221 tcagcaaagg ggcaatttct cttacgaatt gtgtaaaaac atctctgtcc gaaatataca
     5281 tgttttcaaa atcaatatta atgccgtcaa gattatacag tgccgcataa gcaagtattt
     5341 ccctgataag gttgtccctt gcgtcggtat tgtttaaaaa tttgctggtc atttcgctgt
     5401 cggtaaagtc attacttaaa agggcccata cctgataacc tctgctatgg gcccaatcaa
     5461 catattttga atatgccctg ttgattaact ctccttttgc atttttcacc tgaaaccacg
     5521 tgggagaaat gacgtcaagc cccttcattt ctcccaaaga tgaatggtct tctcttcttg
     5581 tatatatcat gtcccacgca agatttatct taccctttgg aggtgtccac gccggttttg
     5641 gagttttgtc atcagaaatc ttctccacca tcaatttttt cacaaccaca aaacgttttt
     5701 caatatatcc gatggcaccg tcccaagttc tgactttgta ccatttgtca tactcttcaa
     5761 atatcctgag tgtgttttcc gccgtatcac cggaggataa atcaaacttt cttataatag
     5821 gctcgcgtat cgaacggcct tttcttacaa ccgcctccgg atcaataggc tcagctatct
     5881 gttttatgct gtttttatag tcaataataa cgacattgct cttttcaacg tatgacactt
     5941 caataccgta aaattcggcc aaaaactcaa taggaatata caccacgtca ttttccaccg
     6001 ttacagggat attaagagtt ataggctggt tgttgacaat tgcgtcaagc ttgtccgtct
     6061 tcattcttat tactctgtct ttcgtggtta tggtgacttt gcccaaagct tcgtcccaga
     6121 aaatatgagg gtcaaaatat tcttttacaa tgtcgaaagg aagaagcacc tcaccttcca
     6181 aaatctttgg gctgttcttt gaaagtacct tttccccttc gacaaccaaa accaattccc
     6241 cttcggcaaa agcaggaact acttcgtcat tgggcttaaa ataaaggtaa taccctgcca
     6301 gcggaattgc cgccagtact gccagtaaaa caacaatcac aaaacaacct aaaattttct
     6361 ttttcatttt gttcccccat aattacaaaa taatcatttg tctaacatta tacaataaaa
     6421 ttattaattc gacactaaat aaaaaaagga agccctcctt gacctcctgt ttttcgccaa
     6481 tatcccacgc tattcaaata cttttcccgg tatcatcagc ctgatggatt ttaacatttt
     6541 ttcgttgggt tcaaaaaaac caaaaccctt ttggactttg tcctatcctc atcctcgtca
     6601 atcttttttt tggcaacaaa aacatagatg tcctcggaat ccaaagaact tacggccatt
     6661 atcctgtctt ctatttcctc aaggtatttg cttatcttgt cggaatctgc tttggcgaaa
     6721 atttcgaatt ccctgcaatt tgcacttatg aggttctctc tctttctctt gttgactatt
     6781 ttgtcaatat caagctctcc gttggtaaag gcatattcat actcaattct tcttgatgaa
     6841 attaccatat aagtcaaata cactactgcc agacacaata tcagagaagc accgtaagga
     6901 cccaaaaaaa gtattattgc actaataaca acaacagcca aagctattga accaccgatt
     6961 atcagcatat cattgccgtc caacttcttc tttactaatt tttccacaaa tatatccact
     7021 tttatcctcc ccagtgaaca taaaataata attcaaagat actttataat tctatcttcg
     7081 aattcattat aaatcaatgg cttaaacaaa atttcatctt ctgtggcaag tgtgccgagt
     7141 atatcctctt ccataagttc tatgggcaaa atgatctgaa catgcatgtc cggaaaatct
     7201 gtttttatat ttcttaccgt atccacaact tcatcattca atgtatttgt atcaattatt
     7261 accagtttag gcttctcttc tgtcagatag tcaaaataga acttaaagtt gtttattaca
     7321 tcaaaatttt cagctccaag ttttatgagc gattccctga tatcatagct ttcgtcaata
     7381 tcggaactga aaataacaat tttggtgtca aacctcatgt cggaagttct tttatattct
     7441 ctgaaaatgc tcaaagattt aaaatatttt tcttcaaatt ttaaaagctc ggtatttaaa
     7501 atgtcccagt tctctttact catcccggca aactgcactc catagccgaa ttcaccgttt
     7561 cccagctctg atactcttaa tatttttgca gacgtaacaa attcttttga tgaatcaaaa
     7621 taaagcttca tatctatcat gctgttaaaa tcgagcttca cattggaaac aaacatggct
     7681 ccgcctttgc ttatgttcct gacagtggct tctttccacg aactttcaca cttttggccc
     7741 gcatcctttt cttttattcg ggaattaata ttaacgtcaa atcttatatg ctttcttaaa
     7801 ttgtaatatt tttttgcatc aatgtatttt atggtcacgg ttgccggagc atcttcgctt
     7861 ttattgtcaa tatgcccgtt tattatgtac tcataccctt tgctctggaa ttttatgaca
     7921 gctttgccgc acacatcacc aggcaaagta atctttgaag cgtcaaccaa aatatccacc
     7981 tggtcttcac cggcatataa tatgggaagt accgtccata catcatcgtt ttcaaatctt
     8041 acacgcacaa gattggtata ttgcatgaca ttaaacaatt cttccttgct tacggaaata
     8101 acactcatgt ttaatctcct tttacagaaa atgatttgag tgcagaatac tgaacaagac
     8161 atgaactgaa ttgcctatat tatatatttt ataacttttg taaaataagt tcaatacctt
     8221 ataaatatca gccgttattt caagtttttt gaaaggaata aataataacg cgggacacat
     8281 aataacacat aaataaaaga gagacccttg acaacaagga tctctctttg tttatccaca
     8341 tttatggcac ggttcagatt agtacattcc gcccatgccc gctccaccgg ggcctccgct
     8401 tgtttctttt tcaggaatgt cggcaacaac actttcagtg gtaagtacca ttgaagcaac
     8461 ggatgcagca ttttgcaaag ctgaccttgt tacttttgca gggtcaacta ttccggcttc
     8521 aatcatgtta acatattttt cattgtatgc gtcaaatcca ataccaggtt cgctggcctt
     8581 aaccttttca actattacgg aaccttcaag acctgcattt tcagcaattt gtctaaccgg
     8641 ctcttccaaa gctctcaaaa taatctgtac accggtcttt tcgtctccgg atacagtatc
     8701 gagaaccttt gcaaccttcg gaataacatt taccagagct gttcctccgc ctgctactat
     8761 tccttcttca acggcagcct ttgtagcagc aagagcgtct tcgattctca atttcttttc
     8821 cttcatttct gtttcagtag cagcaccaac ctggattaca gctacgccgc cggcaagttt
     8881 tgcaagtctt tcctgaagtt tttctctgtc aaagtcggaa gtcgtctctt caatttgaga
     8941 ctttatggat gcaattctct tctgtatttc ttttggatct cccgcaccgt caacaataat
     9001 tgtgttttct ttctgaactt taacctgtct tgctctaccg agctgttcaa cagtagtatc
     9061 cttaagttca agaccgaggt ctgatgtgat aacctgaccg ccggtgagaa ttgctatatc
     9121 ttcaagcata gcttttcttc tgtcaccaaa gccaggtgct ttaacagcaa cgcatgtgaa
     9181 tgtacctctt aatttgttta caagcaatgt tgcaagagct tcgccctcaa catcctcagc
     9241 aatgataacc agtttcttgc cctgctgaac tatctgttcc agcaatggga gaatgtcctg
     9301 gatattgctt attttcttgt ctgtaatgag gatgtaaggc tcatcaagaa cagcttccat
     9361 cttttcagtg tcagtaacca tgtatggtga tacataacct ctgtcaaact gcataccttc
     9421 aactatttcg aggtttgtgc ccattgtctt tgcttcttca acagtgataa caccgtcatt
     9481 tgtaactttt tccatagcat cggctatcaa ttcaccaata acttcgtcat tggcggaaat
     9541 tgaagcaacc cttgctatat cttcttttcc tttaaccttc tggctgattt ccttgatacc
     9601 ttcaactgcc gcatcaacag cttttgctat acccttttta agaagcatcg ggtttgcacc
     9661 ggctgcaacg ttcttaagtc cttctctgat tatagcctgt gcaagaagtg ttgctgtagt
     9721 tgtaccgtca ccggcaacat cgttggtttt tgtggcaact tcttttacaa gctgcgcacc
     9781 catgttttca aacggatctt caagctcaat ttctttagca atggttacac cgtcatttgt
     9841 aatcatcggt gaaccgaatt tcttgtcaag tacaacgttt cttcccttag gtccgagagt
     9901 aactttaact gtatctgcta attgattaac gcctctttcc agagctcttc ttgcttcttc
     9961 accaaatttt atttgctttg ccatatgatt aacctcctta ggatactttt tgtattgaag
    10021 ttggtaatat aattactcta ctaccgccaa aatatcgttt tgtcttaaga tcgtatattc
    10081 ctgtccgtca aattttactt ccgtaccggc atatttgctt ataataacct tgtcgccgac
    10141 ttttacttcc atttttactt cttttccgtc taccaccgtt ccgggaccta ctgctacaac
    10201 ttcagccacc tggggttttt cctttgccga acctggtaaa acaataccgc tctttgtagt
    10261 ttcttcagtt tctaccattt taacaactac cctgtctcct aatggtctga tattcatatt
    10321 ggtacctcct ctttcaaatt ttttatttca acctgctttg gcttatgtat tcatttgtta
    10381 gcactcacct aaggtgagtg ctaatcacaa atataatatt attatattac ccttttcgtt
    10441 atcaaacatg catttttcct aaattttatc gttttacgga gataggcgcc gattgtaagt
    10501 aaatacattt caaattcatt aatttactca atttttcgat taaaataaac cgcttgtatc
    10561 agaggttgac tcttgttttt ttccaatagg caggagcacc ttaaacaaat tctgggaacc
    10621 aatatttata aatttcacag gtccaatgcc ggtaaaagat tttttcaccc tttttaatcc
    10681 aactcccgat ttcataaacc tttttttggg atccaaggtc agaagtcttt gatacagcca
    10741 tggatttcgc ctgtcgggat tgatctctct tgaaaaactg tagacactgt tgccggcaat
    10801 aagagctccg ggattgctaa tttcaatatt tttatccgta accgttatta caattccttt
    10861 tgaaacatcc aaatagtccc tgtgaacaag agcattggca attacctctt ccaaagcatt
    10921 aaaaggatat ccttccacct ttattatgct tctcatatag tcggatacat catcgagcat
    10981 ctttaaaata ttcccgaaaa acagccgggc ctctccattg taaacgactt ttacataaac
    11041 atggggaagg tacaaagaag gatttttccc aaacagcaaa agccctccta tggttggatg
    11101 gtattcctcc gtatcggact tttgtccgat tatgcccaaa gcctcaagaa tcaactcact
    11161 gggattgtcg ctaaaaacat tcagagtttt gaagtaatcc ttaataagcc cgaagtccag
    11221 ttcctccata ccgacatttt ttaatatcac cgtctcatag gtcataagac cgttttcctg
    11281 aaaaagattt gcaatttcac tgcgccttgc tatgtcggtg gttgaacctc ttcttatgta
    11341 aaacgcaccg ttttgtatca tctgatgggg cttatgactg cttctgtaga cagtgataac
    11401 cccgaccgtt tttccatcca gcccgacaaa gtccactgat atcggcacag gtgggtcaca
    11461 gcggttgtaa attatctgct gaatctgctc ctcagtatat cttttaggct caattcccag
    11521 cactcttttg gttttgtctt caatgcccag gataatgtaa cctcgcccgc ccctggaatt
    11581 ggctatggca ataacgtctt tggtgagctc ttttttcccg ctttcagtgg ataaatcata
    11641 ttctgcctta aagtcaagct ttggaccctc ttccttttta agcagccgcc tcagcttatg
    11701 gcaatccatt cccagacctc cgtgacgcct tcctatctcc tttttctaag ctcctcataa
    11761 atgtcttcca gcttgattcc tctttccacc atcaaaacaa ggagatgata aatcaaatcg
    11821 gatatttcat acacaatttc acctttatcc ctgttctttg ctccgataat aacctccgcc
    11881 gcttcttctc cgactttctt taatattttg tccagaccct tttcaaataa ataatttgta
    11941 tatgagccct ctttaggatg tattgttctg tcaactatga catcatatat ttcctgaagt
    12001 atctttgcat tttctgcctc atacaccttt tgctcgtcaa aaaccttgtc agaagtttct
    12061 tttagttcat tccctgaaat ttccctgtaa aaacaggagt aatgccctgt gtggcaggcg
    12121 gcttcaacct gctcaacttt aataagaagc gtatctgcgt cacaatctat gcttatggat
    12181 ttaatgagct gaaaatgacc cgaagtctcc ccttttagcc acaatttgtt tctgcttctg
    12241 ctaaaataat gaaccttgcc tgtttccaaa gacttcttca gggcctcttc attcatatat
    12301 gccatcatca ggacttcatt tgtcttatag tcctgggtaa ttaccggaat cagacccctg
    12361 tcatcaaatt tcaactcttt taagatattt tccattttac tgcctccgta tccaatctac
    12421 attcttattt ctattccgtt ctccttcaaa tattttttta gttccattat ttctatctct
    12481 ctgtagtgaa acagagatgc agccagcaca gcgtcggcct ttccctcaac taatgcttca
    12541 cggaaatgct ccatggtacc ggcaccgccc gatgcaataa caggaatcct tacactttcc
    12601 gacacctttc tggtaagctc aatgtcatat ccttttttcg taccgtcaca gtccatgctc
    12661 gtaagaagaa tctccccggc accgagtttt tcaacctcca cagcccattc cacggcatct
    12721 tttccggtat tgattcttcc tccgttaata tacacatccc aaccggaatt gtcgtcgcgc
    12781 cttttcgcat caatcgcaac caccacgcac tgacttccaa aacgggatgc ggcttccgat
    12841 atcagctcag gcctttttac cgcagcggaa ttaatggata ctttgtccgc accggctttt
    12901 aaaatctccc tgaaatcctc aacggttctt attccacccc ccacagtgaa gggaataaaa
    12961 acctgctctg caacccttct taccacatca atcatgatgt ttctggcttc cgccgaagca
    13021 gttatgtcaa gaaaagtaag ttcgtcagcg ccggctttgt cataatagga cgcaatctca
    13081 accggatctc cggcatctct tatattcaca aaattgactc cctttaccac cctgccgttg
    13141 tgaacgtcca ggcagggaat tattcttttt gtgaccattt aattcacccc ttatttcgcc
    13201 acttctatgg cttctttcaa atccaaatcc cctgtataca atgccttccc gacaataacg
    13261 ccggaaacgc ccacgttttt gagatttctg atgtcatcta tgtttctgac tccaccggaa
    13321 gcgattactt caatatttac ggctttcacc atttcctcca tggcttttag attcggaccc
    13381 gccaacattc cgtctctgga tatgtccgta tatattatgg tttttgcacc cagctcttcc
    13441 atcttctttg caaagcctat tgcagtaaat tcactggttt ttgcccagcc ttctatagcc
    13501 accatgccgt cttttgcgtc aattccaatt acaacgctgt cctcaaaagt ttttaaagcc
    13561 tgttttacca gttccggatt ttttactgcc gaagtcccca atattacgcg gtgaattccc
    13621 ttgcacagga gagtttctat cgtttcaaca gtccttattc ctccgcccag ctgtacagga
    13681 ataccaagct ttacagccat ttcacttata atcggagtgt tctgaatctg cccggttctt
    13741 gccccgtcca ggtcaaccac atgcaaatac tgtgcgccca ttctttccca cttcaatccc
    13801 atctccacag gattgtcgga ataaacggta accttgtcaa attctccctg tacaagtctt
    13861 acgcaccttc catccttaat gtcaacggcc ggataaataa tcatgatttg caacaacctc
    13921 ccaagctaaa ttaagcgcct tttaaaaagg tttttattat tcaaagaatt tttatttatt
    13981 agatatgatt cccgcaaaat tttttaatat tttaagtcca acttcaccgc ttttctcagg
    14041 atggaactgg gtagcaaaaa cattttgctt ttgcaccgca acagagaagt tgataccata
    14101 gttggttttt gcaatgacaa tgtcttcatc atcagtgtcg aggtaataag agtgaacaaa
    14161 ataaacatac ggtttttggg gaagcccgtc aaacaacaaa gacttgtttt taagctccag
    14221 actattccat cccatatgag gcaccttaag attcatgcca aagggaagct gtttgattgc
    14281 accttttaag atcccaagtc ccttcttatt ctgtccacct tcttcactgt actcaaacaa
    14341 aagctgcatg ccaaggcaaa tgcccaaaaa cggttttccg ctgtcaataa ccttttgtat
    14401 tacttcaatc attccgcttt ttgaaagact gtccatggca tccgcaaagg ctcccactcc
    14461 cggaagaacc acagaatccg catttaaaat aagttcttta tcagaagttg tccttgcatc
    14521 ataaccaata aattgaaatg ctttttccac gctttttaaa ttacctactc cataatctat
    14581 taccgctatc aaatttgttc actccacaca aaaaattaag tatatacacc caacactccc
    14641 cttctaaaac aagtaaaagg ggagtgtttt aagttacgca aacttgttgc ctgtaattcg
    14701 ttcataagct tcaatgtact taagctccgt attcttaacc acatcatcag gaagagtcgg
    14761 agccggcggt ttcttgtccc agccgatgct ttcaaggtat tcccttacaa actgcttgtc
    14821 aaaactcttc tgagcccttc cgggttcata ttcattcata tcccagaatc ttgaggaatc
    14881 gggtgtaaac aattcgtcac ccagtacaat ctttccgtcc agaataccga attcaaactt
    14941 tgtatccgcc agaataatgc ctctgctctc cgcatacttg cttgcttttt cgtataatgc
    15001 caggcttatg tccctaagtt tggtagcaag ctccgtgcct atggcattgc agagcccttc
    15061 aaaggacaca ttctgatcgt ggccctccgt ttcctttgtg gaaggcgtaa atatcggctc
    15121 aggaagtttg tcagcctgtc ttaaaccctc cggaagtttt attccgcata tgcttccggt
    15181 ggccttgtaa tctttaagtc cggaaccctc aagatatcct ctgactatgc actcggccgg
    15241 aatcatcttt atcttcttta ccagcatgga acggccttca agttcttcct taaatttcga
    15301 aagtccttca ggatattcac tgacatcagt ggttataaca tggttgtcca cgatatccct
    15361 ggtgtaatca aaccagaact tggaaatacc gttcaaaacc tttcccttat tgggtataag
    15421 gttcggaaat accacatcaa aagcagatat cctgtcagta actacaatta acagtttgtc
    15481 tcccaaatca taaacatttc ttaccttacc tttaatatat aaaggaaggt ctataaaatt
    15541 tgtgtctcct aacagcattt tcaaaacccc tcttattaaa tatgtagatt tttaattttt
    15601 atttatctgt aataatttta taaaatgctc atcaataatt ttaattttaa taaaatttgc
    15661 ttacaacatt cctttagttg acataacccc ttcaattctg tcatcttttc tggtggcatc
    15721 gtccagagct cttccaaagg ctttgaacat agcctcaatt atatggtggg tattgctgcc
    15781 gtataatgcc ttgacatgca aagttatgcc ggcattgaag gcaaccgccc ggaaaaactc
    15841 ttcaacaagc tccgtctcca tattgcccag cttttcacat ttaagctccg catcaaaaac
    15901 caagtaaggt cttccgctta aatcaagggc aaccagcacc agcgcttcat ccatgggaac
    15961 aaaagaagaa ccataccttc tgatggattt cttttcaccc agagcctgct ttatcgcctg
    16021 gccaagtaca attcccacgt cctccacggt atgatgggca tcaatttcca aatcaccctt
    16081 tgcttttaca tccaggtcga aaagaccgtg ttttgcaaac aaattaagca tatggtcaaa
    16141 aaaccctact cccgtggaga tgttactttt gccggaaccg tcaatattta tgcttaaagt
    16201 aatatcggtt tctccggttt ttctgcttac ttcaaacttt ctatccatta atgtgcctcc
    16261 gaaaaatacg taatcaattg taatcaattc ctatcggtat tcaccagata aactatttta
    16321 attctatcat ttctatagaa aatcgcaact ataatgttcc ttaaaaatta ttaattatgt
    16381 cggaaaactc ctctaagaaa atatcatttt gttctttggt tcctacagtt atcctgatac
    16441 agtcgtaaag caccggatca ttgggaaagc ttcggatgag tattccccgc ttttgaagtt
    16501 ccttgcttat catctcagct tcaggcactt tgacaagtat ataatttgca tgggaaggat
    16561 aaatgcagac atcctttatc tttttcaaag atttctccag ctctcctctt tgctcaatca
    16621 aataccgtat cattttctgc atctcttcct gttcctcaaa caccattttt gctataagct
    16681 gggtcaatga acttacattg tatgtcggtc ttactttgtt tatctcattt gcaatctcaa
    16741 ttccgcttat ggaatatccg caccttgctc cggcaagaag atacgctttg gagaaagtgc
    16801 gcagcaccac aaggttttca tacttcttta caagaggtat cacactctgc gggcaaaatt
    16861 cggcatacgc ttcatcaaca acaataattg aacttttgca ctctttcact attttttcaa
    16921 tatgctccag aggaacaagc cctcctgtcg gattgttggg attgcaaagg aataccacct
    16981 tggcattttc cgtttttaca gcctcaataa acttgtcggt atccaaaaca aagtcttttt
    17041 ccttgtcaag gggaaatgcc accggttcac cgcccgctat cagagtgttt attttataca
    17101 tcgaaaacgt gggccaggga tacagcacct tctccccttt ccccacaaac actgttatta
    17161 tcagctgaat aagctggttg gaaccggtac ccacgataac ctcatccgca tcaacattcc
    17221 agtattttgc gatggtcttt ctaagctcca cagactcatt atctggataa atgtttaaac
    17281 ccggcccttt taaaaagtag tccgccagtt tcttcctgat actttcagga agctcgaagg
    17341 gactttcatt tgcgtcaagc tttattctgt acgggacctg atgggaaaca tacggtacta
    17401 atttttgcag ctcaggtctt accaaatcct taatcattcg tacattacac cccccctttt
    17461 ttatttgcag ccaattaatt atttatttgc cgaatatatt tctaaatata ttttttgata
    17521 atattttttt gctgctgtta cgttttttgc cgttgtatga tttttattta atttatttct
    17581 ttttcgattt gtttttacct ttttgttcct ttttctatat tatccttttt taatttcctt
    17641 tctttattct ctttcctttt atgctctctt tttatttgtc ctgtccgtcc tgaaacctca
    17701 ctctaatggc atttgcatgg gctcccaatc cttcggactc tgcaaagagt atgacatcgt
    17761 ctttaacctt ttgaagggca tctcttgtat atgaaataat gctgcttttc ttcataaaat
    17821 ccgaaagatt taaaggtgag aagaatcttg ccgtaccgct tgtggggagc acatggttgg
    17881 gtcctgcaaa atagtctccc aaaggctctg tggaatagtt gccaaggaat atcgcacccg
    17941 cattctttat atcccccagt gcggcaaagg gatcttttac gcaaagttcc agatgctccg
    18001 gcgcaattct gttaaccacc gtcgcggcat ccttgaggct ttccacaata attatcgctc
    18061 catagtcagc tatcgatttt ccggctattt cttttctttc caaaaccgcg agctgagcct
    18121 caagctccct ttgaacctct ttggcaatat cctcagaagt tgtaaccaaa attgatgaag
    18181 caagtatatc atgctctgcc tgggataaaa gatccgccgc cacaaacaca ggatttgcgg
    18241 tctcatcggc aaccaccatt atctcgctgg gtccggctat catgtcaata tcgcaatagc
    18301 cgtataccgt cctctttgcc attgccacat atatgttccc cggccccaca attttgtcca
    18361 ctttcgggat tgtctccgtt ccaaaggcca gggcggctac ggcctgcgcc ccacccactt
    18421 tgtatatttc atcaaccccg gcttcattgg ctgccaccag tattgcagga tttatctttt
    18481 catcctttcc gggaggcgtg gtcattacta ttttgcttac accggccacc tttgcaggca
    18541 ctgcgcacat gagaaccgat gaagggtagg ccgctgtccc gccgggaaca tacacgccga
    18601 caacctccaa aggtctgtaa agctgtccga caattacccc ttccttttcg gtggaaaacc
    18661 aggatttctc cttctgcttt tcatgaaaat tccaaatatt gtcccttgac ctttttatca
    18721 cttcaacaag tttggggtca acctttgtgt acgcctcttt tatttctttc tccgtaaccc
    18781 ttaattttcc taaagtgagc tgaaccttgt caaacatggc tgtatattcc agcacggctt
    18841 tgtctccgtt tcgccgaaca tttgccacta tctcctccac ccggtccaaa acatccctat
    18901 actccagctg acttcttgat gcaaggtttt caaatatgtc gctgtctttg ccgcatctta
    18961 aatcaataat ttttatcatg tatttcacct cttttccaat tcttttcgta ttgcgtcaat
    19021 tatcggattg attctttcgc ttttcatttt catacttacc ctgtttacca caagtctcgc
    19081 acttatatcc gcaattgtgt ccagcaccac aagtccgttt tcctttaagg ttctgccgct
    19141 ctccacaagg tccactatca cctcggaaag ccccaccaaa ggagcaagct cgacagatcc
    19201 gttcagcttt ataacctcaa tggactcttt tcttttgtgc tcaaaatact cccttgctat
    19261 cctgggatac tttgtagcca ctcttttgtt ggtgagccgg tcaagctttc ccattagctc
    19321 cgccgggcct gccaccacca ttttgcaggc ggcaaatcca aggtttaaca cttcataaag
    19381 gtgtcttccc tcttccatca gcgtatcttt tcccacgata cctatgtctg ctgctccata
    19441 ctccacatat gtaggcacat cactgggttt cgcaagaaag aatttgattt tgtttttttc
    19501 atcagtcaga ataagctttc tggatgaatt tttaagctcc gtgcaatcta ttcctatggc
    19561 ttcaaacagc tccaccgaca tatcggtaag ccttcccttt gaaagtgcta ttgtcagata
    19621 cctcatttct tcccctcctt agctcatgcc ttcaaaagct cacttatggt cacttttgag
    19681 acttctccct tttcaaggtt atgaatctct atgttttcat catcaagaac cttcaatatg
    19741 cctcctatgc cctttaaagc cgcataattt ctggctgttt caaagtctcc gccgtttata
    19801 tccacctcca cggcaagtcc ttgttttctc aaggtttcac atatttgaaa agctgttttc
    19861 cttccttctt ccctatagca gacaagagta tcaaccctgg gtttttcaaa ttcaactttc
    19921 tgcctgtcga gggccatcat taccatattg attcccatgg aaaagcctgt tgcggggctg
    19981 ctctttccga atttctccac caaccggtca taccttccgc cgcttaatat cgggaacccg
    20041 actccgtagg taaaacctct gaaaatagta ccggaatagt aattgagact ttgtaccatg
    20101 cccaggtcca ccgaaacata ttttgaaagg ccataatcgt ccaatatatt aataatgctc
    20161 cttaaattgt tcaaggcttt aattgaacgc tcatttatag gatacttttc caccctgtca
    20221 ataacatctg ttgaaccgaa taatttagga aagtccaata tcagctcttt aaggtcatcc
    20281 ctgatattgt gctcctcaac caattcctca attcccaaaa agtcttttcg gtctataagc
    20341 accctcatct tctcggtctc ttcttccgaa agaccggtct cttccatcag ccctttgaaa
    20401 aattccacct gaccgatatc aatctggaaa ttttcaagtc ctgtagcctt tacagcatca
    20461 attgccgtag ctataacctc ggcatccgct tccggagtgt ttactcctat tatttcaaca
    20521 ccggcctggg tgaactcctt ttgctttcct ccgccaagct cgttatattt aaaggcattg
    20581 ccgatatagg agattctcaa gggataagcc gcatccttta gcttggtagc cgcaaccctg
    20641 gcaataggta ttgttagatc cggtcttaaa accagaattc ttccttgctg gtcaaaaaac
    20701 ttaaacatgg tttcctgagg aattatattc tcttcggtgg aaaaaacgtc ataaaactct
    20761 acaatcggag tctccacctc atagtaaccg ctggcccgaa atacttttct gatccgatcc
    20821 tccaggtttt tcttaaagaa acattcattt tgcagtatat cttgaacacc ttcaggagta
    20881 tatatcttcc actctgccaa tttaagcacc tcactttatt actttatcac tttatcatgt
    20941 taaagttata aattgatgaa ctaaggttat tataattcat gtggattaat ttgtcaatga
    21001 gaaaaatgag gtaaagaaaa atatttgaga aacttaagtt tcgcaagtct agagcctgta
    21061 aatactcctc ggggcctttg caaaactcgc ttcgctcaaa caatgctctc cctttcctcg
    21121 tcgtattaac aggctctacg acttgcttca caatgtttct ttcatatttt tctttacatg
    21181 aaaaaactga ggggttataa atgatacaaa gaagatatat gttttatatt tttcacataa
    21241 ataaagtgta tttattaaat gcctggaagt aatttcccca atcgaaaaaa gaacatgtca
    21301 tcgaatctat atatcatcag atttatatgg tacggtatag tttaatactt atgacttttt
    21361 tataacacag ttaataaaag cagtatattt ataatttata aaaaaagggg gataaattat
    21421 gaaggcatcg aaagttgggc agaaggttat cttgttttta gtgtcttttt cattgttcat
    21481 ctcatgtatc acaatttcag caaccgctgc caatggcgga aaattgggag acataaacag
    21541 cgacggatcc atcaattcca ccgatgtgac tttattaaaa agacatcttc tcagagaaaa
    21601 catacttaca gggacggcat actccaatgc tgataccgac ggagacggaa aaataacctc
    21661 catcgactta agctatttga aaagatatgt attgcgcctt atatcttctt ttccgggcga
    21721 aacgtcaaat aatcttaaca taccctggga ttgggtcgga atcataggaa cgggacaaag
    21781 tctctccgta ggaactactc caattttatc tacaacccag ccttacaaca atcttaagct
    21841 ggatttgggc aacctgaggg ttcctcccta cgatgccaac agcagtgaac tgaaactggt
    21901 tccccttacc gaacctattc gcagccttgc aacaggtttc ccgtctgcct acccaaggaa
    21961 cctatatggt gagacccccc atagtgcaat ggcgaaccaa ataactgcaa tggtaaaagc
    22021 tgcaggcgga aacgactata tttcagtaca tacggtagta ggtgaatccg gtcagggtat
    22081 gtctgtaatc aaaaaaggtg ccaccgatac tggaaatacc ggccgtgcct atgcggcatc
    22141 aatatttgaa gtcacagcaa ttaaccgctt ggcaaaagcc gcgggaaaaa cctacggggt
    22201 gggaggaatc atcctaaccc atggcgaaac cgattgcggt aatcccaatt atgaaaatga
    22261 gctacgccaa ttgtggtcgg attataacaa ggacataaag gctataaccg gacaaaccca
    22321 aaatatcccg atgtttgttg tgcagcagca ctcctatcca agtacgggaa cttccgcttc
    22381 caccttggct cagtggaaag caggtgttga ttatcccggt gatataatct gcataggtcc
    22441 aaattatcag cgaacttacg gaggagataa cgtccatttg acttctgccg gatatcaaca
    22501 tttgggtgaa aagtacgctc aggtatatta tgaaaaggtt atcctcggta aggactggaa
    22561 acctcttcag cctataaaag ccaccaaaaa cggcagaacc atcatagtag acttccatgt
    22621 accggtaccg ccccttgttt gggacaatac gcttccggca ccaaaccaga acaccttgac
    22681 cgaatggaga aacggcaaag ggtttgaggt tactgccaac ggttcaagag tcacaataaa
    22741 ttcggttgaa atctcgggaa attcggtaat aataacctgt gccagtgaac tgcccgcttg
    22801 gggtgtaaaa gtcggctatg cctttaccgg cggaaaagca agacctaacg gaacctaccg
    22861 ctggggtttg ctgcgcgact cagatccctt cataggaagg tccggtgtgg cacagcccaa
    22921 tttctgtgta tcttttgaaa tgcccgttaa ttaagtatta ataaaataaa cttaaacaca
    22981 aaggcatcag attaattcat ttttggtagt ttcacttaga gcctgtaaat actttgtcag
    23041 gccgggcaaa atccacctta taaggatagt gcctcaccct gtctcaatgt attaacaggc
    23101 tctgcatcta tatccggatt ccactccaca gtagcaccga atgcttcact tttactttaa
    23161 tatcaatttt ttgtattggg aaataagtcc taagccttca tcttcttaag tatcatccgt
    23221 attttccgta tcgaagttgc cttctgtctc tccattcccg ggcttcatct ttgaagaata
    23281 taaatcctcc ggctttttta tgtgcaaaac aaaatttgaa aaagtatagt atttattaaa
    23341 ctccttttcg gttaacagta atctgccttt taaagaatct ccgacaacaa aatggtctcc
    23401 ttctttgcct aaaatcgtta taaagtggcc tatcctgccg ttaatataag ttccgattat
    23461 tgacggtacc ggtacatcgt tcaaactgtt tttgtatgaa acttcagttt cgagtccgtt
    23521 cttttccgca tacctgatta aataccaatt ctccgtaccg cttgaactgg aaaaggctgc
    23581 ccttgcaatc tcttcttcac tttttgatat tccataataa ttaaaaattg tcgctaatgc
    23641 tgcaggaccg caagttgaac ctgtagattg caaacacacc ccatctttcc atcggtcttg
    23701 aaactgagaa ttccggctta caggtcttat aatcggttta ataaaaggta ctataattaa
    23761 aagcatgcag ataacgaata tatatttatt aaaaactttt aacttaattt tcccaaagct
    23821 ttcatctttg aaagttacaa atccaaagaa aagacctgtc agggatgata acaactcaat
    23881 attgtcaatc gccctaaatt taatatacca tacaggttca tttataaaat gcatgtaata
    23941 tgccccaaac agaaagtttg gaatacaaag gaggatgaac acaaaaccca aaagaatcct
    24001 gacgggtttt ccgctcaccg cccttgaggt tctttgccct ataataaaaa gtataatgcc
    24061 gattattaca gccggaaata ttgcacggtt aaaatacatt ttgaaacctc tttctattgt
    24121 ttttgaatat ttatattaaa aatattatat caaatttttg gctccggaaa atatcaataa
    24181 tactctttcc caaaatgaat tcaggctgta ccgggagcaa ccccggcaca gcctaaatta
    24241 atcaatcctg taaacacctg aatgttattt attttatctc tatctcgtat ccgtcttttt
    24301 ctatgtcaca atcttcactt gtacctacaa tatatgcctt caaatatttt gcttttccaa
    24361 taacatcttt atagttttcc atatcaagtt tttcttcgaa ttccactgtc tttccggcgt
    24421 ctatcaccgt ctcggtcagt acacctataa atcccttgtc ggcggaccag gtatagagaa
    24481 tttctttatt tttgtccaac agtttgaaat caaacttttg tcctgatgag tggttaatag
    24541 ttatatcccc gtcggatgta tttttgagct tgagcttcat cgtgaaagta ttctggctct
    24601 tttcatattc cggcacaact acaagactgt tttccttact ctctgttatc tctacctcgt
    24661 atccgtcttc ttctatttca caatcctcac ttgctcccac aatatatgcc ttcaaatacc
    24721 ttgccttttt gacaatatcc ccgaagcttt ccatatccag ctcatcggca aactccactg
    24781 tctttcccgg atctattacc gtttgagttt ccatcattat aaatatcttg tcagcagacc
    24841 aggtgtaaat tatttcttta ttttcatcga gcaatttaaa gtcaaacttt tgcccagatg
    24901 tgtgattgat tgttattggt tttttcgatg tattctttat tgaaagcttc attgtaaagg
    24961 tcttttcgcc ttttttatag cttggtacta tctcaagctt attatctttt tcttctttga
    25021 ggcttaaata atatccatcc tcatttattt caaaatcctc actgcttcct actatcacgg
    25081 ctttaaaata atatgccttg ccgctgattt catcgtaagt ctttgcatca agaatttccg
    25141 aaaattccac tgtctttccc gccggaatct ctgtacttgt caaaatctca acaaatgctc
    25201 tgtctccaga ccacctgtac agttcttctt ttttatcatc aagcagtaca aaatcatact
    25261 tttgcccgga aaagtgttgg attacaacat cttttttgct gttgttttta attgtgagcg
    25321 ccattttata tccgtcttca tgtttttcaa acgaaggaat aacttcaacc tcggccttta
    25381 tattttcctt caaagcctgc attaattttt ccagaactat catggcttca gcccttgtgc
    25441 tgtatccttt ggggacaaat ttcccattgc tccttcccct gacaaatccc agtttaaatg
    25501 catacttcac agattcttta tactgcttct gaatactctc ctcatcatca aaacacttgt
    25561 ctttctcatc aatttgatcc aaaacaatat taagcttgta tttatatgta tttacaagat
    25621 aatgcaccat ttcctcacgg gttatgaggt cattgggcct aaacttctcc ctgtcgtcaa
    25681 ctatgtttag tgatgccaga tcatacagag tcgaagcata ccagtcttcg ttttttacat
    25741 catcgaaaaa ttcattgatg tccggagcct tgaagtagtt aattttaatt tccgctgctt
    25801 tgtgcaaagc cacaataaat tcggaccgtt ttatctccct atccggcaaa aacataccgt
    25861 tgccaacacc tttgactatt cccaagtttg ccattctttc aattgtgtcc tttgcccaat
    25921 gccccgaaat gtctgaaaaa accgtgtcgt atcctgtggc tgccgccgca gctgtactta
    25981 gcatcataat gccgagaacc aaaataattg acagtactcg cttcactttt attacctcct
    26041 cttgtttttt taataataat taaaacttct aattaattaa aacttctggc gccatgtttt
    26101 cctgtttgta ttcttagacg taatcatatt ctgtttggtt cgggcattat gaagaaatat
    26161 aaaaaatatt attaattcac cttagtcaga ttcgcatagc tttccaaaag cctcttcatg
    26221 ccttttccct taaaatgtat ctccagtttg aaatcatcgc cgtcaggctc tctttttgtt
    26281 ataattcctt ccccgaagac tttgtgccgc accacgtcac caactttaag ctccgttttt
    26341 gacgtctccg tcctttgcac aggcttaaag cttaccgcat taaagctttt agaagagtta
    26401 aagtccttgt ttaatgtacc gctctttttt gccgttcctt cgccaatgtt ctcatccttt
    26461 gctttctttt tatccccgcc gaaatcaaaa agctcctcgg gaatttcttt aacaaatctt
    26521 gaaactctgt tgtaggtggt atttccaaac aacgtacggc tgaaggtgct tgtcatgtaa
    26581 aggttttctt tcgccctcgt tatgcctaca taacaaagcc tcctctcctc ctccagctcc
    26641 gattcattgg tcattgacct gtaacccggg aaaatacctt cctccattcc caccagaaat
    26701 accaccggaa actccaatcc ctttgcgctg tgaagggtca taagagcaac atattcactg
    26761 ttttcatcca tcgtatcgac atccgaaacc agggacacat gggcaagaaa atccgtaagg
    26821 ctcttttcct cgctttcatt ttcaaattca attgcaacgg agagcaactc ttttatgttt
    26881 tctattctgc tctgggcttc cagggtattt tcctgtctat acgcctccaa aatgcccgtc
    26941 ctctcaagga cctcctcaat catttccgat gcggtcatca ccatactttg ggccctcagg
    27001 ctgtttatca gcgagacaaa cttttcaagc tttgacgaag cccgggcaag ctcgggaatt
    27061 tccgccgccg atgaaataat tgagaaaatg ctgactcccc tttcatttgc cagtctctct
    27121 gcagtatcta tggtcgcatt tccaatacct cttttaggct catttattat cctctttaga
    27181 cttatgttat ccgaaggatt ttgaataaca cgaagatagg caattacatc ttttatttct
    27241 tttctgtcat agaacctaag ccctccaaat atcttgtagc ttattccttc cctcataagc
    27301 tcatcctcaa taacacggga catggcattt atacgataaa gtacggcaaa atccttgtaa
    27361 gagcggttct gctccctgca gagcctcttt atctcacttg ccacaaaata cgcctcttca
    27421 tgctcattca ggcactcgag atatctaatc ccgtctcctc ctttattgtt tgtccaaagc
    27481 cttttggctt ttcttcccac attgttcttg ataacatggt ttgccgcatc aaggataatc
    27541 tgggttgaac ggtagttctg ctcaagcttt attacttttg catccttaaa ctccttctca
    27601 aaatccagaa tatttcttat attggcgcct ctccagccat agatggactg gtcgtcgtcc
    27661 ccaacaacac aaagatttct gtacccctgt gccaaaaggc ttacaaggga atactgggct
    27721 gtgttggtgt cctgatactc atccaccaga atatatttga attttctctg gtaataattc
    27781 agcacttcgg gattgtccaa aaaaagcttt atcgtaagca ttataatatc gtcaaaatcc
    27841 aaagcgttat tttgcttcag cttcttttga taaagctcat agacccgggc gatcttctcc
    27901 atcctgaaat ctccggaata catttttaaa taagagtccg gagtgataag ctcgtccttt
    27961 gcccttccga tcatctccaa tattgacttc ggaggaaagt ttttatcact gagattaagt
    28021 tccttcaggc agtcttttac aacattttgc tgatcggcat agtcaaatat cacaaagttt
    28081 ttatcataat ctattttttc tatatccctt cttagtatcc ttacacacat ggaatgaaaa
    28141 gtacttaccc atatactgtc actgacatct tcaacaagcc ggtctattct ttctctcatt
    28201 tcccttgcag ccttgttggt aaaagttatg gcaaggatac tggcaggatg tacatttttc
    28261 tctttaatta aatacgcaat cctgtgcgta agcacttttg tctttccgct tcccgcaccg
    28321 gcaagaacaa gcaaggggcc gtcaacgtga agtaccgctt ccctttgttc cttattcaaa
    28381 tctttcaata aatccatatt tcgtcctctc caataaataa aaatttaaat gccgagacat
    28441 atgcctcggc attttcaatt atattagaaa atcctttata tatcaatatt ttatcatttg
    28501 ctattatcaa gttaaaattc cggttcaatc aaaccataat ttccgtcttt tctcctgtat
    28561 accacatttg cttcattggt ttcagcattg gagaacataa agaattgatg tcccaaaagg
    28621 ttcatttgca aaatagcttc ttcaaccgtc atgggtttta tggcaaattt tttcgttctt
    28681 acaacttcaa attttggttc ttcttcgact tcatcatcat caaatttaat gttttcaaac
    28741 cttaagctgc cgtcatggac tttcttttca agtttggtct tgtttcttct tatctgtctt
    28801 tcgagactgt ctataacttt gtcgattgaa gcgtacatat ccggactgtc ttcttcagct
    28861 ctgagcaatc ctccttcgaa gggtattgta acttccacta tgtgcctgtt tttctgcacg
    28921 ctcattgtga ttgttgcttc agcatcgcga cggaagtact tgtccagttt tccgactttt
    28981 ttaacagccg cttcttttaa agcttcagtt acgacaatgt tttttccgac aactttgaat
    29041 ctcatatatg tacacagccc ctttccgtca ataacaagta ttgtaacttt tacaatactt
    29101 gtgtgctatt attaataatt ttacccagag aattttcatt aaaacacgac tttgctttaa
    29161 aaaataaaaa acatccaccc ccattttttg aaattgacaa gaccaaatca atttgcaagt
    29221 cgcgtttggc cggttcttcc aaggcttccg ggtaaaaata ttaatatttt attatattaa
    29281 ttcgacatca agtaaaatat tccttcaata taattataac cgagggaatt gatatttttc
    29341 aatctcggat tgacgatttt ccacatgaat tcttttagtt ttccagcctc caaacttatg
    29401 cagaaagctt tattcacatg cttttccaca attatctcac atttgcccca caaaacaagt
    29461 gttttgtgca cataaacact gtggataatg tggacaattc tgtgaataac tcatataggc
    29521 tgactttacc tgtggataat tccgttgtta tctttaaaaa cttcaccgtt ttatgttaac
    29581 acatttttcc ttatcatatt tgtcatatat aaatttttat tgcgggaaat acctttaaat
    29641 attgcttttt gaggatttta tttccaacaa caatatattc cgaactcatg catagccata
    29701 tttggaactc aaatccatga ttatgtaacg tcagtaaacc attacttttc gttttattca
    29761 tcaaaatatt gatttacgcc gtttaatttt ttgtggaaat tgcatattgt ttaaattcat
    29821 aaagtttgtg ataattagaa taacaagagg atagaaaatt cagggtgtga tgtataacac
    29881 ggtaaagtat atatcatctg attcagaaca ttatatccgt tatcgtcgca gctacaagta
    29941 gcaatgtatt gaaaaatcca cgtaccaatc catgcaataa attgattccc cggccatacc
    30001 aattaccgct ccaatttgac acccgtcaac cggtattaaa acgcagtcag cattacaccc
    30061 ttttttatat tattgattga tgccagacaa acatataaaa acaaaccaac taagaagagc
    30121 gaaacttaag tttcggtctt tttttttgct tcgaaacatg tattatcccg aaacccatat
    30181 taaaacctat attatattcg taaccctgtt tgcaccaagc caggaaatat ttaaaattta
    30241 aataatccaa ataagaagca aaattataaa aaggagtcgt gacaaaacat cacgactcct
    30301 ttttccactc attgggatat taaccgttat actctttcaa acgttgttca agagcctcca
    30361 attgtgccca caattctttc ggcagttttt ctccgtatga cttataatgt tcttttattg
    30421 actcaacttc ctggagccac tgttctttgt taacgctcaa gagttcttcc atatcctctt
    30481 tgcttacatc aaggccggtt gtgtcgatag cgtcaactgt aggcatatat cctataggtg
    30541 tctttactgc tttacctttt ccgttgactc tttcaacaat ccacttgaga acacggctgt
    30601 tttcaccgta tccaggccac aaccatttac cgttgctgtc cttgcggaac cagtttacat
    30661 agaatatctt gggaagcttg cttgggtcag tcttggtacc catgttcaac cagtgctgca
    30721 aatagtcatt tacgttgtag cctatgaaag gcagcatagc aaacgggtca cggcgtacct
    30781 gtccgatttt gtttgaaatt gcggcagccg taatttcaga acccatgatt gaacccatga
    30841 atacaccatg gttccagtca aagctttcat gaacaagcgg aatggtgttc ggacggcgtc
    30901 caccgataag gattgctgaa atcggcacac cttccggatc ctcccattca ggagcaatta
    30961 cagggcactg acttgcaggt gctgtaaaac gtccgttggg atgtgctgcc aaagttccgg
    31021 aatcaggagt ccagtcttta ccctgccagt ctatgagatg agccggcggt tcagttccga
    31081 tgccttccca ccaaacatcg ccgtcatcag tcaatgcaac gtttgtaaat atagtatttt
    31141 tcttaattgt atgcattgcg ttcggatttg aatccatgga tgtacccgga gcaacaccaa
    31201 agaatcctgc ttcagggttg atagcataca aacggccgtc ttttccaaat ctcatccatg
    31261 caatatcgtc accgattgtt tcaactttcc atccgggaat tgtaggaata agcatagcca
    31321 ggttcgtctt tccgcatgcg cttgggaaag cacctgtaac atatgtcttg tttccttcag
    31381 ggtctgttat gcgaaggata agcatgtgtt cagcaagcca accttcgtca cgtgccataa
    31441 cagatgcaat acgaagtgca aagcatttct ttcctaaaag cgcatttcca ccgtatccgg
    31501 aaccatatga ccatatagtc ctttcttccg ggaagtggct tatgtatttc ttttcgattg
    31561 gtgcgcatgg ccaaccttta tccttttctc cctctttgag cggagcaccg actgagtgga
    31621 gacaaggtac aaaatctccg tcttctccga gctgatccaa cacagccttg cctatgcgag
    31681 tcataatgcg catgttaaca acaacataag ggctgtcggt caattcaacg ccgatttttg
    31741 aaatgggtga accgataggt cccatggaga aaggaataac atacattgtt cttcccttca
    31801 tacaaccctt gtacaactct ttcatagttg ccttgagctc aaccggatct atccagttgt
    31861 ttgtaggtcc tgcatcttct ttggttttgg atgcaataaa agttctgtcc tcaacacggg
    31921 caacgtcgga cggatcgctg cggaagagat aacatccagg tcgcttttca ggattcaaag
    31981 gcgtagccaa acctgaatcc accatcaact ttatcaagcg ctcattttct tcctccgaac
    32041 catcgcacca ataaatttca tcaggctgac acatttcagc catttcctta acccaatcca
    32101 gcagtttttt gttttttgtc atgtttgttg atgtcatcag aaattctcct tccaactata
    32161 ttattatttt tttatgatat tacatttgtg ttgtttgcat ttttgttgtt gcatttttgc
    32221 aatataagta aaactaaaaa tactctggat attttttctt cccgagcaat tagttaattt
    32281 tttcactaac atactaacac aaaaccgtca aaatatcaac aaatcttttt gggttttttg
    32341 caggttttgt tctacaaaaa ttcatctgat ttttatgcat ttatatgcat acaacattac
    32401 atatggaaat tattgtgctt tattattgtt tttatacacc gtactttgcc taatatatag
    32461 tttttacaca tctttttttg tgatagaata actttgtaaa tgtaaacaat ttatatggga
    32521 ggataaaatt aataatgaaa aaaaatgttg tgttgattct gggaattgtt tttaccgcag
    32581 caggtctgat tcccatttta atcggcgtaa cttttttcct ttctcattac aattttataa
    32641 gcaatgccgc cagaaccacc gctgttgtta ccgatataaa gtcctaccgc gactttgacg
    32701 gtgataaaca ttacgaagtg gtaataaaat attccgtgga aggagaagaa tactacgaaa
    32761 ttattgcaca ctcccctttg atgtatgtag gcagggaaat caccgtctat tatgacccaa
    32821 ataagccgag gcacgttaaa accatgggtt tcgtcttcga tgatctcttt ttggttggaa
    32881 tcggattggt attttttatc attggaatta gctttaccgc atcacagttt aagaaattca
    32941 gacttcgcaa acggttgttg gaaaccggcc ggacagtata cgcagacatt agtgaaatca
    33001 ctttgaacac aagctataca gtaaacagta agcacccata tgttattacc tgcaagtgga
    33061 aagatcccga cacaggattg ttttactttt ttaccagcga caatatctgg tttgatcccg
    33121 aacctataat acacgaaaag ggtattacca gtcttccggt atatatagac cctgaaaatc
    33181 caaaaaatta ctttgtctca gtcaaggata tagaaatgtt cgtggcaaat gtctgaaact
    33241 tcacttatat ggcgcacaat ccttaatttt tccctacgca tatacatttc aggttgattt
    33301 aaccccgaat attttataaa attataatag gataagtatt cctgcataaa tggtattgta
    33361 aatttactcc agaggaggtt atgcttaaaa aatattttta tagaacaact attttacaga
    33421 acaacatatt ttcactggtg caattacctc ttttattttt gcttcattgg cccggttaac
    33481 aattttcaat aatatatttt ttattgaaca aattattttt ttggggggaa ggtattttta
    33541 tgaaaaaagc aaaagcaatt ttttcgctgg ttgttgcttt gatggtattg gccattttct
    33601 gctttgcaca gaataccggt tcaacagcta cgacagcagc ggccgccgtc gacagcaaca
    33661 acgatgactg gttgcactgt aaaggcaaca aaatttacga catgtatgga aacgaagtct
    33721 ggctcacagg cgccaactgg tttggtttca actgcagtga aaactgtttc cacggtgcct
    33781 ggtatgatgt taaaaccatt ctgaccagca ttgcagacag aggtatcaac cttctgagaa
    33841 taccaatttc aacagagctt ctgtacagct ggatgattgg aaaacccaac ccggtttcca
    33901 gtgttaccgc cagcaacaat cctccatatc atgtggtcaa ccctgacttt tatgatcccg
    33961 aaaccgacga tgtaaaaaac agtatggaaa tcttcgatat cataatggga tactgcaaag
    34021 aactcggaat aaaagtaatg attgatatac acagtcctga cgccaacaac tccggacaca
    34081 actatgagtt gtggtacgga aaggaaacaa gcacctgtgg tgtggttacc acaaagatgt
    34141 ggatagacac tttggtttgg cttgccgaca agtacaaaaa tgatgacacc ataatagctt
    34201 ttgacttgaa aaacgagcct cacggaaagc gtggatatac ggctgaggtg cctaaattgc
    34261 ttgcaaaatg ggacaattcc acagacgaaa acaactggaa atacgctgcc gaaacctgcg
    34321 caaaagctat tttggaagta aatcctaaag tgcttatagt aattgaaggt gttgaacaat
    34381 atcctaaaac tgagaaaggt tatacctatg acacaccgga tatctgggga gcaacaggag
    34441 atgcttctcc atggtacagt gcatggtggg gaggaaactt aagaggtgtt aaagactatc
    34501 ctatcgattt aggtcctttg aacagccaga ttgtatattc tccgcatgac tacggtcctt
    34561 cagtatatgc tcagccgtgg tttgaaaaag actttacaat gcaaaccttg ttggatgact
    34621 attggtatga tacctgggca tatattcacg atcagggaat cgctccaatc ctaatcggtg
    34681 aatggggcgg acatatggac ggcggcaaaa accaaaaatg gatgacattg ctcagagatt
    34741 acatagttca aaaccgcatt catcatacat tctggtgcat aaatcccaac tccggtgaca
    34801 ccggcggatt ggtcggaaac gactggtcaa cttgggatga ggcaaaatac gcattgttaa
    34861 aacctgcttt gtggcagacc aaggacggaa agttcattgg acttgaccac aaaattcctc
    34921 tcggttcaaa gggaatttcc ctgggcgagt actacggaac accacaagct tcagatcctc
    34981 cggcaacacc gactgcgacg cctacaaagc ctgcagcttc atcgactcct tcatttattt
    35041 acggcgacat taacagcgat ggtaatgtca attcaacaga tcttggtata ttaaagagaa
    35101 taatagtaaa aaatcctccg gcaagtgcca acatggatgc tgcagacgta aatgcggacg
    35161 gtaaagtgaa ttcaactgac tataccgttc taaagagata tttgctgagg tcaattgaca
    35221 aactgccgca caccacctga caatcaacag gacttataat aaaattaaag gttgactgcc
    35281 aaacaaaggc agtcaacctt ttttaatatc cataatttaa aatcattctt ccttcattcc
    35341 cgtataaatc aaaatggcat ccctcaaaaa ttctgcggtt cccggctgat ccttgtcata
    35401 atatgccgca aacctctcgt cctcaacata cattttggca agcccggcat gggcttcttt
    35461 gctgtaactt tcccaaaaac agcacagcca ttgtcgatgc aggtctgcag ccttttgtgc
    35521 aagctcccct gcaggatctc ccgttgcaaa ggcttgcttt aataggtttt ttagctcagc
    35581 agaaagcctc tccgcttctt catactgctc tttggtcatg tttttaagct ttctgtaaga
    35641 cttgtcaacc tcttcatccc catatttttc ccttatctct tccccatact ttctctcatt
    35701 ctcttcaatc attttttgtt tgaaaccttc aaatttctcc ttgtctgtca tttcggctct
    35761 cctttcagca gctgcaatag tcttttccac atttgctatc aacaaatcca gctgctctct
    35821 ttttcggata aacatacttt acacctttac gctgcgttaa catcaacaac ttttttacgc
    35881 tctgcacacc ttaatttttt caatcctttt ttcacttacc tcttccactt tgaataaaag
    35941 tccgttgaac tcaatttccg gcttttcatc atactccgga attctaccca actgacttat
    36001 aataaaaccg ctcaatgtgt catactcgtc ctcaggcagc tgcgcgtccg cccattcatt
    36061 taaaacatca agacctgcgg tgccgctgaa tatataagtg ctctcatcca atttttcgaa
    36121 atctttttct tcttcatcgt attcgtcaaa tatattaccc acaatttcct ccacaaggtc
    36181 ttcaacagtg acaattccgg ccgttcctcc gtactcgtca ataataatcg ccatatggac
    36241 cttgtttttc tgcagctcgc tgaaaagctc gtctgccttt ttggaccaag gcacattata
    36301 aggctttctt attatctttc ttaaatcaaa gtctgcagta tcactcccga cgcctatata
    36361 ttttattaaa tccttgacgt gaagtatccc tacaatgtta tctatgcttt cctcatacac
    36421 cggtatcctt gtgtattttt cctcattaaa caaggatata acttcatcaa gacttgcatc
    36481 aaccggaaga gccacaatat cggttctatg ggtcataata tccataaccg tcttgttgtc
    36541 aaaatcaaaa atattattga tcatttcctt ctcgttttcc tgtatggtcc ccttttcttc
    36601 tccaacgtca accatcattc gaatctcttc ctcggtgacc tcttcctcgt ccgcattggg
    36661 gtcaattccg aaaagtctga ctatcaaatt ggttgaagca ttgagaagct ttacagcagg
    36721 ataagtgaca actgaaagga tataaagcgg cctggcagca aacatggata tggcttcttc
    36781 tttcttcatc gcaagtcttt taggaaccag ttcgccaatt accagtgaaa aatatgacaa
    36841 aattacagat acgaaaatca tggacagagt cttaagcact gcatccggaa caggtacacc
    36901 cgtctgtttt ataagtcctg ccaaccggtc ggaaaaactc tcggacgcga aagcactcga
    36961 caatgttccg ccaagagtta taccaatttg gatggtggcc aggaacctgc ccggttcaga
    37021 taatagtttt ttcaatattt caatcttctt tttgctcttt tcattgccca tcaacctgag
    37081 cttgttgtca tttaaagata tcagagcaat ctcagaagcc gcaaaaaatc cgttcagcac
    37141 tatcagaagt attaaaacca gaatctcaac aaacaattaa aatcatcctc cacaagataa
    37201 aataagacta aaaaagagca taataaacct tgtctacggt ttactccagc cctcttatag
    37261 cccttttgta tttatcaatt tttatattgt ttattttcat attacactct gatcttaata
    37321 acttccatag tgcctttccg atctgtaaat ccgccggata atcatccatt attttatcac
    37381 cccattaaat ttatcaattt ttcgctttta tataattaat tctatataat taaaaataat
    37441 taaattaaat ttaataatta aaaataatta aattaaattt actatttttc atgataaatg
    37501 tcaagccgct taaaacccaa caaaaaccat tttccttgat ttaggcggtt aaatcacgtc
    37561 aacttggcac catttctcac ctgcccgaca acaacattac caagcactaa attcctaaat
    37621 ctttcaaact ttcggaaaat tttgtaattt aaataaaaac ttcggatatt ttaataatat
    37681 ataagtataa atataagcat agttttttat tccataggat atttaagtcc ccactttgcc
    37741 ctgagtacat ccaaaatttt catgacttcc aggctctcat tcaaaggcat aatatcactt
    37801 tccaactttc cttccttaag gcatttattt acttcctgaa cctggtagtt caagccgttg
    37861 gatacaaaag gaatcctcac aaccttttct tcccgcccgt tcaaatgaat tgaaaactga
    37921 gtgggatgaa agaaatccgg aacctttatg tatccttccg ttccgcaaat tacagcatca
    37981 tgaggcatgt caacactata tgaggatgac agcattgcca cttttccaaa tccaaactca
    38041 aacatatagg ctgcatgcac atcaactttt gaatcggcta tatatccaaa agtctttata
    38101 ccaacaggag attttttaaa cacaagtctc gcaaaagaaa caggatacac tcccaaatcc
    38161 agcagcgcac ctccggcaag attggggtca aagtagtatt ttggcacatc ccgacctttg
    38221 gtactgtttc caaagtcagc ccgcaaaaat ccgatgtctc ctattatgtt ctgagaaagc
    38281 aaacggttca gctcgactat gcacggcaaa aatcttgtcc acatcgcttc catcaagaaa
    38341 actttgtttc gccttgcaac tttaattaaa tcttcggcct gttttgaatt aacggtgaaa
    38401 ggtttttcgc acaggacggc ttttttattt tcgagacaaa gaagagcgtg ttcgtagtga
    38461 aagttgtgtg tggtggctac atatatgaca tccaaagact cgtcttttac aagttcctga
    38521 tagtcctcat aataacgctc ggcattaaaa atttttgcaa attcggcagc ccgtccgggt
    38581 gtttttgaag ctacagccgc caattttgca tcaggtacgt gctgcaaact ttcggcaaaa
    38641 gttcttgcta ttcttccaca acctaatatt ccccatctta ttttatccgc cataaattta
    38701 tttcctgcct tgtacaattt ttatacttat cttaacagcc tccataagtg acgtgaatat
    38761 gtgccaaaaa ttctcttttt agaaatgcat ttgaccactg tctatatact acaatagtat
    38821 ctataatttt aaaacatgta catgcaattt gtcaatgcag ccctacgctt caaagttctg
    38881 tcgtattgca gtttctatta tttattccca atacacagca ttatttcatg aaaaatatcc
    38941 gacaaaggca cttgaatgtc ggcaagccct gcctcataaa ctacttttgg cataccatat
    39001 acaacgcatg tttcctctgc ctcaacaatt actttcccgt tatatttttt caccgtttca
    39061 cacccaacaa gtccgtcatt tcccatcccc gtaagaataa ccgacaacag cctttctcta
    39121 tagataggcg ctgcagaatc aagggttacg ttaatagatg gtttataaag cgttttaacg
    39181 gacggacagt cttttactct caaagctatt acaccgttcg cctttttatc aaagaacgtc
    39241 tggtaacctg ccggagctat ataaatatta cctgcctcaa caatgtctcc gtcttccgct
    39301 tctttaaccc ttaaattgca aatagcgtca aagcgttcgg ccagcggttt cgtaaatccc
    39361 ggcggcatat gctgcagaac aactatcggc acatgagtgt ccttaggaaa acgcgggagg
    39421 atggactgca acgcagaagg acctccggtg gagcacccta ttattaacaa gtcagctgcc
    39481 cctgtttttg tcttaatcaa atcttccgac ttgctcaaaa tattgtcaag aatttcggac
    39541 actttttcag aatcagtttt ctgtttgatt tctttcttcc cacactttct tgctttttga
    39601 gcaatggctt tcaacctatc caaaaactct cttattattt ccggtttcac gttttcttcc
    39661 agcagcgcat tcttcaaata aaaatccgca gctcccaact ccaaagcctg aaaagttgtt
    39721 tcaggatcct tgtccgtttg gttgctcaac actataacag gaacaggaca aaccctcata
    39781 atctccttta aagcagtcat gccatccatt tcaggcatct ccacatccat tgtcacaatg
    39841 tcaggtttaa gcctttgcac tttttctatt gcttcaattc cgtttcttgc aattcctatg
    39901 ataaaaagtt gtggatcttt ctctataatc aagctgatac atcttctcat aaaagatgag
    39961 tcgtccacta ctaatacccc atacttctgc atggatactt ttctcctttc cgataataaa
    40021 atgtcgacgg cgcatatatc gtctcaaatc cggtattcat tcccgttata gtctctgcat
    40081 ggcctaagaa caaatatccg ccgaccttca gcactttgta taaagagtca acaactctgt
    40141 ttattgcttt cgcatcaaaa tagatcagta cattcctgca aaagattata tccacctctc
    40201 caatcatttc cgctatattt tcatccaaga gatttaaccg gcgaaaatca accatggccc
    40261 ttattgaatc cttgaccctg tattcatctc caaatgagac aaaatatttc tcaagtattt
    40321 cttttggcat tgtgcgaaaa gagaatgatt ttttgttata caagcccttt cttgcttttt
    40381 ccaaaacctt tttgtctata tccgagccga taatctctac tgcaccggct tcaaacagcc
    40441 cgctctcttc aattaatata gccaaagtat atggttcttc cccactggaa caagctgcac
    40501 tccatatacg caaaggatta tcgggtgtac ggccctggta ctttggaagt atgactcttt
    40561 gaaactcttc cagaaggttt tcctcacgaa agaaataagt ctcattgact gtaataagtt
    40621 caataagctt gtcccattct ttcggctcaa cccttaaata acctccgtac tcccaacacg
    40681 aaagccccaa ttccttgagt ctgtctgata ttttactttc aagagaggaa agatttttaa
    40741 aaaagtcaat gccgcaatat tcatatataa gctcagctaa ttgaatcagg ccaaatgtat
    40801 ccatacagat ttgctacagc ctccctgaca gaatctgtgg agaggcataa agcctctcca
    40861 atataatata cagactttga cttatgtcaa actttaatta aaataaatat taagtgctat
    40921 ttagacagtt cctgcagtgc gcctataatc tcttccgagt attccgccaa ttctttcgct
    40981 accgcgcaag tacgctcaac atccttgata ttgaggttaa taacacgatc tatttcagat
    41041 gtatatttcg ccagttgttc tacctcattt gcctgaactt tggcagcatc ggccacttca
    41101 tttgcctgaa cggttacgcc ctcaacgttg ccaataacct tgtcagcatt tactgcctgt
    41161 tccttcatgg ctgctgaaat ctgttttacc tgttcacggg catttgcaac acttttaatt
    41221 atatcctcaa cgccatgcgc ctgttctttt gtcacattgg taatttgagc agcctggttt
    41281 gcaacgtttt caaccgcagt aactatattc tgtccctgct ttgcctgttc ttttactgtg
    41341 gtggtaacct gacgcatctg ctctcttgca ttctcaatac ctcttattat gtcttcaata
    41401 ccttgagtct gttctttcac tgcatttgtc acaagagccg cctgttcgct gacattttga
    41461 acagatgcgg taatatcctg tccctgtttt gcctgttcct tgacagctgc ggtaatctgg
    41521 cgtacctgtt ctcttgcatc ggcaacgctc ttgataattt cctcaactcc cgctgcctgt
    41581 tcttttacag cctgtgtaac ctgggcagcc tggttggtaa cattttctac agccctaata
    41641 acaatctgac cctgcaaagc ctcttctttt accgcagtgg taatctgttt tacctgctcc
    41701 cgggcattta ttacaccttt gataatttgt tcaacacctt gagcctgctc tttggcagcc
    41761 tgggttacct gcgatacctg attggtaaca ttttccacgg ctgtcacaat attttgtccc
    41821 tgttgtgcct gttccttcac cgcagcagta atctgcctta cttgttctct tgcattcaac
    41881 acacccttga tgatttcttc aacgccctga gtctgctctt ttgctgcctg ggccacctgg
    41941 gctgcctgtc tgtttacatt ctctactgcg accacgatat tctgaccttg ttttgcctgt
    42001 tctttcactg cttccgtaat ttgtcttacc tgttccctgg agttctctat gccttttaca
    42061 atatcctcaa cgccctttgc ctgttctttg gttacatcag ttacctgtgc cgcctgtttt
    42121 gtcacatttt ccacagcaac cactatgttc tggccatgat ttgcctgttc tttcacggca
    42181 agagtgactt gacgcatctg ttctcttgca ttttcaatac ctcttattat gtcttcaatg
    42241 tcttttgcct gctctttggt tgcctgagta acctctgcag cctgtttggt cacattttcc
    42301 acggcaacca ctatattctg gctctgtttg gcctgttctt tcattgctgc cgtaacctgt
    42361 cttatttgct cacgggcatt ggccacacct tttattattt cctcgacacc ggctgtctgt
    42421 tcttttacgg cagctgcaac ctgggcagtt tgctgagtta cgttttcaat ggactggaca
    42481 atattttgac cttgctttgc ctgttctttt actgcaagag taacctgcct tacctgttct
    42541 ctcgcattgg ccacaccttt tattatttcc tcaacacctt ttgtctgttc tttagtggcc
    42601 tgggtcactt gggctgcctg atttgtcaca ttttccacgg cagttatgat attttgaccc
    42661 tgttttgcct gttcctttac tgccacagtg acctgtctta cctgctccct tgcattggcc
    42721 acacctctta ctatattttc cacacttgcc gcctgctctt tggtagcctg ggttacctgg
    42781 gctgcctgat ttgtcaccat attcacagca tcaataatct tcatgctgcc cttgttctgc
    42841 tcttcggtgg cggcagttat ctggcggatt tccacgttta cattctctat tccctcaact
    42901 attttctcaa tagcttttcc ggcctcatca ctcagctttg aaccgtgttc aaccttttgg
    42961 gtgccgactt ctatggcctt gatggcctga cttgtctctc cctgaatgcc cttaatcagt
    43021 tcggatattt cctttgttgc tgtggctgtc cgttcggcca attttcttac ctcgtcggca
    43081 acaactgcaa atcccttgcc gtgttcacca gctcttgcag cctcaatcgc cgcgttcagt
    43141 gcaagaagat ttgtctgttc ggcaatatca tcaatcacct ctataatact gcctattttt
    43201 tcggagctct tcccgaggcc gtttataaca tcctccgcac gatgaataac ttcagatatg
    43261 tccttgatag ccactaaagt atcagccact gctttctggc catctatagc atcacttctc
    43321 actttttcgc tcaattcatt tacattctgg gcattctggg caacctggct tatagaggct
    43381 gccatgtttt caactacctt ggatgtttca ttggctgatt tttgaagctg ttcagcattc
    43441 ccggcaacac cttggattga tttgcccatt tcttctatcg aagaagatat ttcttcaaca
    43501 gatttggctg tactttctgc gttacctgcc acctgctgga tggacgcaac tatctcctgt
    43561 atcgcagccg aggcctcgtc agccgaagcc tttaaacttt cggcatttcc tgcaacacct
    43621 tctatcgacc tgcccatttg ctctattgaa gaagatattt gttccacaga acttgctgtg
    43681 ctctccgcat tgcctgccac ctgctgtatg gaagcaacta tctcctgtat tgcagcagca
    43741 gattcgtctg cggatccctt tagactctcg gcattgcctg caacaccttt tatggatttg
    43801 cccatttgct ctatagagga agatatttgt tccacggaac ttgctgtact ttccgcattg
    43861 cctgccacct gctggatgga cgcaactatc tcctgtatcg cagccgagga ttcgtctgcc
    43921 gatcccttta ggctctccgc attgcctgca acgccctgta tggacctacc cattttctct
    43981 atggatgcgg ctatttcctc aaccgatttg gctgtacttt cgctatttcc cgctacctgc
    44041 tgtatggaag atattatttc atgtacggca gctgacgctt cttcggccga acccgacaga
    44101 ctttcggcgt ttcctgcaac actttttatt gacttgctca tttgttcaat ggaagatgaa
    44161 atctgctcta cagagcttgc agtactctct gcatttcctg ccacctgctg gatggacgca
    44221 actatctcct gtatcgcagc cgaggcctca tctgcagaac cttttaggct ctcggcgttt
    44281 cctgccactc cttttactga tttacccatt tgctctatgg aagatgatat ttgctctatg
    44341 gaacttgccg tactctctgc atttcccgcc acctgctgga ttgacgctac aatctcctgt
    44401 attgccgccg aggcttcctg agccgatcct gacgtacttt cagcattgcc tgccactcct
    44461 ttgatggatt tacccatttg ctctatggaa gatgatatct gctctataga gcttgcagta
    44521 ctttcggcat ttcctgccac ctgttgaatt gatgaaacca ttgaatgaat ggcatttgtt
    44581 gcctcctccg ccgaatttga gagactctcc gcatttacgg caactccatt gatagatctt
    44641 cccatctgct ctatggaaaa agatatacgt tctatggaac ttgcagtatt ttcgctgttt
    44701 cccgctacct gctgaatgga tgcggccatt tcctgaactg ccgctgtagc ctccctggct
    44761 gaaccggtaa ggctctcggc gttccctgcc acacctttta tggacttact catctgctca
    44821 atagaagatg aaatctgctc tacagaactt gcagtgcttt cggcattacc ggccacctgc
    44881 tctatggaac ccactatctt ctgtatagcc gacgaaattt cttcagccga gcctgtgagg
    44941 ctttcagcat tgcctgcaac gccttttatg gattttccca tctgctctat ggaagaagat
    45001 atttcttcta ccgattttgc agtactttca ctgttgcctg caaccagttt tattgtgcca
    45061 atcatacttt caagagattt tttggactct ccggcaagct ccttcagttt ttcggtattt
    45121 ttaacaacac cgttaattga ctgggaaagc ctttcggcca ttgaatttgt tgaatcaacg
    45181 gctgaagact gttcacttgc accttttgca acctgctcgg tgataccgga caaatccttt
    45241 aatttttcat cgagtttttt agctgagctg actgtttcgt agattttctg agaaagctct
    45301 gaatttttca attttacagc cttatgtctt ctaaatccca taaacaacgc ctcctatttg
    45361 tgtttttgaa ataatcactg tgttaactct tcatcattta tttgtaagta ctcgccgttt
    45421 attttagatg cctgtctatt gtttactata ttcgcaactc ctaccacgtc caatatacag
    45481 gccacacttc tgtctcccaa gattgtagct ccggaaatac cttccacttt gcctatataa
    45541 gacccaaggt ttgtgacaac aacttcctga tttcctatga gttcatccac cacaagtcca
    45601 aaacgttttt cagctattcc caccaaaaca atcagcatat ttttcctctc ttcgtctcgc
    45661 ggcacaccga agtagtcatg cagccatacc aaaggaatcg ctctgtccct tataactgcc
    45721 actgcctgtc cattgatgga ttcaatctca tttttcggtt tcctcacaat ttcaaccaca
    45781 ttatccatgg gtagcgcata agtttcattg ctgattttga ctaaaagtcc tttcaatatt
    45841 gcaagggtaa gaggaagctt gattggcagt ttgattatga actttgtccc tctgcctgga
    45901 cacgtctcga catcaatgat tccattcaac ctttcaatgt ggttccttac aatatccatt
    45961 ctgactctat agtcagaaac atcacttgca ttttgcgaag cggaaaagtc agcgtggaaa
    46021 atgaggttta ttaactgctg ctcagtcatg ttgtctgctt cttgttccgt aatcaccatc
    46081 ttttcaatgg cagattgctt tatcttttgc acatcaattc cagctccgtc atcttcaacc
    46141 gttataatta cattactgtc ctcaggcaat gctgctatcc gcaatttccc cttctcaggt
    46201 ttccccagct tttttcggat ttcctgattt tcaatcccgt aaattatagc attccgtata
    46261 agatggatta acgggtcact gatttcttcc atgatagtcc tgtctatttc ggtctctcca
    46321 ccttcaagca ccaaatcaat ttccttattc aatgaaaggg acaaatctct gaccattccc
    46381 ggaaagcgac taaataactg ctgcaccgat atcatacggg ttttcattat tctatcttga
    46441 agctcattga ttaacaccgg tatacggttt gaaataccta tcagttcatc aacagtttcg
    46501 tcaaaagggt actggttata taaattattt gaaatctggg cgatccgtat ctgttcaatc
    46561 acaagctcac caaccagttc catcattctt tccagatggt ctatatccac ccttacagta
    46621 tgtacaacct tttttccctc tccctctgtt ttatgatcgg gtgcctgatt tacccgttcc
    46681 tgctgctttt catcaagcat aaatatcgtt tggttctttt gctcaacttc tgcattttca
    46741 gccgtatccg aattattatc gtttggtttg ctttgagaca gtatctcctt taatttactt
    46801 atcacagaag ttatttctat atcgatagcg ttctctgcct taatattgtt tgcatcagaa
    46861 tccaaacctt gctttagcat ctttaaataa tccaaactct cgaaaagaag aacaataatc
    46921 ggttcggata tttcaacaag acctctgcgg attttatcca aaatgttttc catttcatga
    46981 ataagagttt ttattttttc aaaatccaca gcagcaaaag aaccttttaa ggggtgtgcg
    47041 atgctgagta attcttcggc tttctgtgtt gccttatagt tttgttccaa ttttgcaatg
    47101 tcttttttga gaagttgtag ctgttcttcc acttcgcgaa ttaaagcctc caacatttcc
    47161 gggctttcag atatgttagc catgctacac tcctttcctt attcatagag tacgctatca
    47221 atttttagaa tgctaactac cccttcatca gtaataccta taccctcaaa gtagctgcca
    47281 tcaattcctg ctatcatctc cggaggtggc tgaatgtccg aaaatcttat gacatggttc
    47341 actttatcaa ccacaactcc aatcatctca tctctactct tcaccacaac aatgcgggtt
    47401 ttttttgtag gagtgtaatt ggtaagtccc aaccttttat gaaggttgac tacaggaatg
    47461 atttttcccc gaagattgat aaccccttcc agaaaaggct ggctgttagg tatcggagta
    47521 atattttgca ttttgataat ttcatataca tcactgattt ttaaagcata tttttcattt
    47581 actaattcac aagccacata tagactggtc aaaagttcat tcataatttt tcacctccct
    47641 tcaaacattg gataaatatt gttaatttta ttgcagtcta taataatgtt tgaataagat
    47701 aacgtaaaaa atagcatgct tgaacccata agtattcagt aatacacttt atgggtcaga
    47761 cagtaaagca aggcaatggt tctttgttca ccatccagca cctttgtcca ttttgggaat
    47821 tctaaatctg caattatgat aagactgctt ctctcatatc gagagaaaca aaacctgaag
    47881 ggcaattaga ctccatcttc gctaagagta agcccaattt atcaagatta agaaagtcaa
    47941 agctttaaag tttttcctta taattatatt gttattttcc gcttctttcg gaggaaaaga
    48001 tttatagact ttactgcttg aggtatttta agcttatccc tataaacttc aaccagtatt
    48061 ttattgatgt gcattatttt cacctctccg ttgttttgcg gcgtatccag caccggattt
    48121 ttgtgttaat taggtcaact tgagctttgt cagttttggt cttcgcaaaa atatgttttg
    48181 atactaatta ttacaatttt aatttcaatt tacataagta ctaattatat atttttttat
    48241 atggtccttc cacttt
//