LOCUS NZ_ACVX01000048 16444 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00051, whole genome shotgun sequence. ACCESSION NZ_ACVX01000048 NZ_ACVX00000000 VERSION NZ_ACVX01000048.1 GI:256005907 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000048. FEATURES Location/Qualifiers source 1..16444 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene complement(397..975) /locus_tag="ClothDRAFT_2714" CDS complement(397..975) /locus_tag="ClothDRAFT_2714" /inference="protein motif:PFAM:PF03167" /note="PFAM: Uracil-DNA glycosylase superfamily; KEGG: sfu:Sfum_1040 uracil-DNA glycosylase superfamily" /codon_start=1 /transl_table=11 /product="Uracil-DNA glycosylase superfamily" /protein_id="ZP_05430853.1" /db_xref="GI:256005908" /db_xref="InterPro:IPR005122" /translation="MSKSERLKELYDLYRKEFQEREIVLGDGNVNSRLVLIGEAPGKD EVLKSKPFVGAAGKNLAEFLDVLGLKREDIYITNAIKYRLSKVKPETNRVSNRPATKN EILENRSYLLKEIEIINPEYIVTLGNVPLRSVYGDFSISIGEVHGTLTRVEVLGTEFN LFPLYHPASIIYNVKLKEIYNEDLNKLRMIIG" misc_feature complement(415..906) /locus_tag="ClothDRAFT_2714" /note="Uracil DNA glycosylase superfamily; Region: UDG; cl00483" /db_xref="CDD:186027" gene complement(954..1523) /locus_tag="ClothDRAFT_2715" CDS complement(954..1523) /locus_tag="ClothDRAFT_2715" /inference="protein motif:TFAM:TIGR00758" /note="TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: nam:NAMH_0477 uracil-DNA glycosylase" /codon_start=1 /transl_table=11 /product="phage SPO1 DNA polymerase-related protein" /protein_id="ZP_05430854.1" /db_xref="GI:256005909" /db_xref="InterPro:IPR005122" /db_xref="InterPro:IPR005273" /translation="MYSWEELIKVCSNCTKCGLSKTRTNIVIGRGNINAPMMLVGEGP GEQEDLQGLPFVGPAGKLLDLLLKAMRIKEDMYYIANIVKCRPPGNRVPTDDEAEMCL PYLRNQLVLVKPRIIVCLGATAMKYIIDRNAKITNVRGQWIERKGYWIIATFHPAALL RDESKKVLMWEDFKKVKQRLDSICQNQNG" misc_feature complement(984..1484) /locus_tag="ClothDRAFT_2715" /note="Uracil DNA glycosylase superfamily; Region: UDG; cl00483" /db_xref="CDD:186027" gene complement(1529..2161) /locus_tag="ClothDRAFT_2716" CDS complement(1529..2161) /locus_tag="ClothDRAFT_2716" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; KEGG: vok:COSY_0397 organic radical activating enzyme" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05430855.1" /db_xref="GI:256005910" /db_xref="InterPro:IPR007197" /translation="MKVNEIFLSIQGESLSAGFPTVFVRFTGCNLRCSYCDTRYAYKE GEDMTPSEVFEEIKKLHYKRVCLTGGEPLLQKELGQLLEFLDDYIVTIETNGSVSLKS VELKNPKHSYVMDMKVPSSGCSDQMLFENFDLLRDNDEIKFVIGSRVDYDWAKNIISK YHKKGTVTFSPVYGKIDYSGIVKWILEDKLDARFQVQLHKVIWGPDKTGV" misc_feature complement(1547..2161) /locus_tag="ClothDRAFT_2716" /note="Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602" /db_xref="CDD:30947" misc_feature complement(<1715..2086) /locus_tag="ClothDRAFT_2716" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature complement(order(1856..1858,1877..1885,1949..1954, 1958..1960,2054..2059,2063..2065,2069..2071,2075..2077)) /locus_tag="ClothDRAFT_2716" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene complement(2187..2570) /locus_tag="ClothDRAFT_2717" CDS complement(2187..2570) /locus_tag="ClothDRAFT_2717" /inference="protein motif:PFAM:PF01242" /note="PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dps:DP0165 6-pyruvoyl tetrahydropterin synthase" /codon_start=1 /transl_table=11 /product="6-pyruvoyl tetrahydropterin synthase" /protein_id="ZP_05430856.1" /db_xref="GI:256005911" /db_xref="InterPro:IPR007115" /translation="MKIGKVSITKLFTFDSAHHLIDYNGKCRNIHGHTYKLEITLKGL PDENGLVMDFHDLEAIIENEVLEKVDHKYLNDVFDFNPTCEMIGLWLWEEISKQVQNT RCTLEKLVLWETPTSYITIDRNDME" misc_feature complement(2214..2549) /locus_tag="ClothDRAFT_2717" /note="Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl...; Region: TFold; cl00263" /db_xref="CDD:185871" misc_feature complement(order(2214..2216,2232..2234,2472..2474, 2478..2480)) /locus_tag="ClothDRAFT_2717" /note="active site" /db_xref="CDD:29764" gene complement(2602..3270) /locus_tag="ClothDRAFT_2718" CDS complement(2602..3270) /locus_tag="ClothDRAFT_2718" /inference="protein motif:TFAM:TIGR00364" /note="TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: cbs:COXBURSA331_A2202 queuosine biosynthesis protein QueC" /codon_start=1 /transl_table=11 /product="exsB protein" /protein_id="ZP_05430857.1" /db_xref="GI:256005912" /db_xref="InterPro:IPR004479" /translation="MRRAVVLLSGGLDSTTCLSVALAEGYEVYPLSFDYGQRNRKELE SAKQVVKYFKLKEHKIVKIGNVGGSALTDMNIDVPDYKGLPTIPVTYVPARNIIFLSY AVGYAEVVDAEAIFIGVNAVDYSGYPDCRPEFIEAFQKAINLGTKSGVNGKPVKIITP LINLSKAEIIKLACENNAPLHLTTTCYRGGEKACGVCDSCVLRLKGFKEAGIVDTIEY MERT" sig_peptide complement(3199..3270) /locus_tag="ClothDRAFT_2718" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.780) with cleavage site probability 0.599 at residue 24" misc_feature complement(2644..3264) /locus_tag="ClothDRAFT_2718" /note="ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995" /db_xref="CDD:73293" misc_feature complement(order(3157..3159,3163..3165,3229..3240, 3244..3252)) /locus_tag="ClothDRAFT_2718" /note="Ligand Binding Site; other site" /db_xref="CDD:73293" gene complement(3562..4341) /locus_tag="ClothDRAFT_2719" CDS complement(3562..4341) /locus_tag="ClothDRAFT_2719" /inference="protein motif:TFAM:TIGR00241" /note="TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: gur:Gura_0484 putative CoA-substrate-specific enzyme activase" /codon_start=1 /transl_table=11 /product="CoA-substrate-specific enzyme activase" /protein_id="ZP_05430858.1" /db_xref="GI:256005913" /db_xref="InterPro:IPR002731" /db_xref="InterPro:IPR008275" /translation="MRVLGIDLGSRTVKLVVFEDGNFVNSMIYDTATFYRDFCSNVNQ KINVDFEKLDIGYFDSVVSTGYGRNNVNVENATVILELKAHTYGAVWQTGLDDFTLLD IGGQDSKVISVRNGKMADMVLNDKCAASCGRYLENMANILGIGLEELAGYHENPVELN STCAVFGESELIGKISEGYGIRELAAGVNYSLFKRIKPIIERFPHENLVVCGGVAQNK ALLEFIKSELDFKRVVIPERPQLNGAIGCCAFRIEKMKLAK" misc_feature complement(3565..>4341) /locus_tag="ClothDRAFT_2719" /note="ROK family; Region: ROK; cl09121" /db_xref="CDD:186831" gene complement(4402..5388) /locus_tag="ClothDRAFT_2720" CDS complement(4402..5388) /locus_tag="ClothDRAFT_2720" /inference="protein motif:PFAM:PF06050" /note="PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; KEGG: gbm:Gbem_0393 2-hydroxyglutaryl-CoA dehydratase D-component" /codon_start=1 /transl_table=11 /product="2-hydroxyglutaryl-CoA dehydratase D-component" /protein_id="ZP_05430859.1" /db_xref="GI:256005914" /db_xref="InterPro:IPR010327" /translation="MKNIGFTTSVPVEVIFAAGYRPVDLNNVFITDDNPGKLIEVAEN TGFPRNICAWIKGIYSAVADMGGIDELIGVVEGDCSNAKALVEVLELKGVQCFQFSYP SSRSYDRLKKEIDRFCSHFGVSYEECLKVKKELDKIRLRLAYLDELTWKHNKAGGFEN HIWQVSSSDFNGDYVTFGRELEDAISSIEKREPKTESKRIGYIGVPPINADIYEFIES LDARVVYNEVQRQFTMADSVGIEDIVEEYRRFTYPYGIRGRLEDITVQVKKRKIDGVI HYTQAFCFRGIEDIIIRKELGVPVLTLEGDRPGKLDQRTRLRIEAFIDMLDE" misc_feature complement(4411..5388) /locus_tag="ClothDRAFT_2720" /note="Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775" /db_xref="CDD:31961" gene complement(5532..6467) /locus_tag="ClothDRAFT_2721" CDS complement(5532..6467) /locus_tag="ClothDRAFT_2721" /inference="protein motif:TFAM:TIGR00350" /note="TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="cell envelope-related transcriptional attenuator" /protein_id="ZP_05430860.1" /db_xref="GI:256005915" /db_xref="InterPro:IPR004474" /translation="MNFRKSILYICVVFSLVLFIQGIYTLLLAKEKYNGTESDDKYDP VEIVKWKIDREDGRKTLNSYINVLVLGLDDDEKRSDVIALINYNPDENKMNILSIARD TRVKVNGKYMKINALIGKGGEKMVIDMVEDITGLPVDYYVTLNFKGFREIVDTLGGVE INVPFDMDYDDPYQNLHIHLKKGKQVLDGKKAEQFVRYRKGNHNGEGYEDGDLGRIKM QQLFMREFVNQKLKLKYLLKADEIFYTLKKNMRTNIEIGDIRYFIKDIKNIKTPEING YTLPGYSRYIGGQWFYIYDKKKTKELIEQNFYYSN" sig_peptide complement(6378..6467) /locus_tag="ClothDRAFT_2721" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.727) with cleavage site probability 0.702 at residue 30" misc_feature complement(5781..6236) /locus_tag="ClothDRAFT_2721" /note="Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581" /db_xref="CDD:186090" gene complement(6578..7810) /locus_tag="ClothDRAFT_2722" CDS complement(6578..7810) /locus_tag="ClothDRAFT_2722" /inference="protein motif:PFAM:PF00155" /note="PFAM: aminotransferase class I and II; KEGG: geo:Geob_1134 aminotransferase class I and II" /codon_start=1 /transl_table=11 /product="aminotransferase class I and II" /protein_id="ZP_05430861.1" /db_xref="GI:256005916" /db_xref="InterPro:IPR004839" /translation="MAFINENYLKLPGSYLFSEIARRVDNFRKENPNAKIIRLGIGDV TKPLAPAVIDALHKAVDEMAKEETFKGYGPEQGYSFLVSKIIEYDYMPRGIRLDEDEV FVSDGAKSDTGNFQEIFGLDNKVAVTDPVYPVYVDSNVMAGRTGKYLANGYFENITYL PCTAENNFIPELPKEKVDIIYLCFPNNPTGMTLSREELKKWVDYARENRAIILFDSAY EAYIREKDVPHSIYEVEGADEVAIEFRSFSKTAGFTGTRCAYTVVPKKVVAYTKNGEA HQLNSLWNRRQTTKFNGVPYIIQRAAAAVYTPEGQKQTKETIDYYMENAKIIKQGLED IGLTVFGGVNAPYIWLKTPDGISSWEFFDIMLKEINVVGTPGSGFGPSGEGYFRLTAF GSRENTLEAVERFKNLKF" misc_feature complement(6590..7771) /locus_tag="ClothDRAFT_2722" /note="aspartate aminotransferase; Provisional; Region: PRK07681" /db_xref="CDD:181081" misc_feature complement(6593..7702) /locus_tag="ClothDRAFT_2722" /note="Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609" /db_xref="CDD:99734" misc_feature complement(order(7040..7042,7064..7069,7073..7075, 7157..7159,7250..7252,7415..7417,7484..7492)) /locus_tag="ClothDRAFT_2722" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99734" misc_feature complement(order(6908..6910,6917..6919,7040..7048, 7178..7180,7385..7387,7481..7483)) /locus_tag="ClothDRAFT_2722" /note="homodimer interface; other site" /db_xref="CDD:99734" misc_feature complement(7064..7066) /locus_tag="ClothDRAFT_2722" /note="catalytic residue; other site" /db_xref="CDD:99734" gene complement(7900..8742) /locus_tag="ClothDRAFT_2723" CDS complement(7900..8742) /locus_tag="ClothDRAFT_2723" /EC_number="5.1.1.7" /inference="protein motif:TFAM:TIGR00652" /note="KEGG: dds:Ddes_1150 diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; PFAM: diaminopimelate epimerase" /codon_start=1 /transl_table=11 /product="diaminopimelate epimerase" /protein_id="ZP_05430862.1" /db_xref="GI:256005917" /db_xref="InterPro:IPR001653" /translation="MRFTKMHGLGNDYIYVNCFEETVENPSEVAKKVSDRHFGIGSDG LVLIMPSERADFKMRMFNSDGSEAEMCGNAIRCVGKYVFDRGMTNKNVIRVETLAGIK VLELTVQDGKAKLVKVDMGEPILKPENIPVNSDKEIFRTEPVEIDGKEFKVTCVSMGN PHAVSYVKNVDIFPLEKIGPKMEHHPLFPKRINAEFVEVIDRTTLKMRVWERGAGETL ACGTGACAVLVASVLNGVSERKATVKLLGGDLIIEWNENNNHVYMTGPAVKVFEGEVD LNEL" misc_feature complement(7912..8742) /locus_tag="ClothDRAFT_2723" /note="diaminopimelate epimerase; Provisional; Region: dapF; PRK00450" /db_xref="CDD:179032" misc_feature complement(8368..8736) /locus_tag="ClothDRAFT_2723" /note="Diaminopimelate epimerase; Region: DAP_epimerase; cl14668" /db_xref="CDD:187422" misc_feature complement(7933..8283) /locus_tag="ClothDRAFT_2723" /note="Diaminopimelate epimerase; Region: DAP_epimerase; cl14668" /db_xref="CDD:187422" gene 8943..9641 /locus_tag="ClothDRAFT_2724" CDS 8943..9641 /locus_tag="ClothDRAFT_2724" /inference="protein motif:PFAM:PF00535" /note="PFAM: glycosyl transferase family 2; KEGG: sun:SUN_1537 glycosyl transferase" /codon_start=1 /transl_table=11 /product="glycosyl transferase family 2" /protein_id="ZP_05430863.1" /db_xref="GI:256005918" /db_xref="InterPro:IPR001173" /translation="MKILVIIPAYNEEATIKNVIQRIKLKMPQADILVVNDGSKDNTS RKAKTAGAKVIDLPYNLGIGGAMQTGYLYAKENGYDIAVQVDGDGQHDPSYIKELIEP IINNSADVVVGSRYISKTNYKSSVFRRMGMIFFSFLVSTLTNQKFKDTTSGFRAVNKE VINYFSNHYPVDYPEVDVLIRLKKRNFRIAELPVEMYKRQGGKSSITTFRSLYYMLKV SLAIIIGTLRSSEE" misc_feature 8955..9431 /locus_tag="ClothDRAFT_2724" /note="DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179" /db_xref="CDD:133022" misc_feature order(8964..8966,8970..8972,9204..9206) /locus_tag="ClothDRAFT_2724" /note="Ligand binding site; other site" /db_xref="CDD:133022" misc_feature order(9051..9053,9201..9206) /locus_tag="ClothDRAFT_2724" /note="Putative Catalytic site; other site" /db_xref="CDD:133022" misc_feature 9198..9206 /locus_tag="ClothDRAFT_2724" /note="DXD motif; other site" /db_xref="CDD:133022" gene 9655..10005 /locus_tag="ClothDRAFT_2725" CDS 9655..10005 /locus_tag="ClothDRAFT_2725" /inference="similar to AA sequence:KEGG:Anae109_1820" /note="KEGG: afw:Anae109_1820 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430864.1" /db_xref="GI:256005919" /translation="MVINVYSLSIMFSVFFLLLVIELVRKNKLQERYCLLWILMSIIL LVLSSTPVIIETVSAWLDIKNPPSLLFLFGLGYLILYNLATTVTVSKQSERITRLTQE IALLRQKITDMNSK" gene 10134..11012 /locus_tag="ClothDRAFT_2726" CDS 10134..11012 /locus_tag="ClothDRAFT_2726" /inference="protein motif:PFAM:PF00535" /note="PFAM: glycosyl transferase family 2; KEGG: cvi:CV_1160 glycosyl transferase" /codon_start=1 /transl_table=11 /product="glycosyl transferase family 2" /protein_id="ZP_05430865.1" /db_xref="GI:256005920" /db_xref="InterPro:IPR001173" /translation="MGTYLISVAIPVYNEAKQIYENINIIHKILTENNINHEFILVDD GSRDNTWEELKRLSVDLPNVLAIRLSRNFGKEAALCAALEAAHGDACVVMDSDLQHPP EIIPQMVRMWREEGYDVVEGVKSSRGKESITNKVGAHLFYSILKNLSGFNLDGASDFK LLDSKVVASWRIMPERNTFFQRNVRLAWIQKSLHSLRSGGKKGRKIKMVHFKTFQTGN NRNNIFFVASASFGYINGHVVSLLLHYNGHLHPVYEVQRFGRKRFHHCHSSAFDNREH INDKSRHYRNLHCKNI" misc_feature 10146..11009 /locus_tag="ClothDRAFT_2726" /note="Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463" /db_xref="CDD:30811" misc_feature 10161..10673 /locus_tag="ClothDRAFT_2726" /note="Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187" /db_xref="CDD:133030" misc_feature order(10164..10166,10170..10172,10422..10424) /locus_tag="ClothDRAFT_2726" /note="Ligand binding site; other site" /db_xref="CDD:133030" misc_feature order(10263..10265,10419..10424) /locus_tag="ClothDRAFT_2726" /note="Putative Catalytic site; other site" /db_xref="CDD:133030" misc_feature 10416..10424 /locus_tag="ClothDRAFT_2726" /note="DXD motif; other site" /db_xref="CDD:133030" gene 11231..12166 /locus_tag="ClothDRAFT_2727" CDS 11231..12166 /locus_tag="ClothDRAFT_2727" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein LOC684087" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430866.1" /db_xref="GI:256005921" /translation="MFKKVVAIFTTMVLLIALTVVSCAENTNYIFNGSFELLIDGEPS NWMREAYDKSPGASNFRVETEGAKFGEKYVTIINNKLNDSRYSQIVLVEENKKYKLSC YIKTENVSEEGKGANLSVAEQTVTSKRIKGTTDDWEYVELYVITESGVDRIKVTVGLG GYSGMSTGKASFDNVTMEEVETIPEGAPRAVVKAQNTKKSSNNSNNTNNTKSSSSQNN ENKNELGKVVLVMLIVGAIAVGVAVYNTFRSNKKVSGNQGNASNNTGTNTNMTESAAN KESAGNKEFSDNNESSHSKEDSSDNSDSDNKESSD" sig_peptide 11231..11305 /locus_tag="ClothDRAFT_2727" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.923 at residue 25" gene 12365..15271 /locus_tag="ClothDRAFT_2728" CDS 12365..15271 /locus_tag="ClothDRAFT_2728" /inference="protein motif:PFAM:PF02366" /note="PFAM: glycosyl transferase family 39; KEGG: geo:Geob_0316 glycosyl transferase family 39" /codon_start=1 /transl_table=11 /product="glycosyl transferase family 39" /protein_id="ZP_05430867.1" /db_xref="GI:256005922" /db_xref="InterPro:IPR003342" /translation="MSKKLFKVCLILLISIQFIFSSPVFAESENLVKNPGFEEGNDES VYFWQTHCWEKAEGVTEFFIDESVYHSGGKSACIVNHSENDSRYMQPIKVKGDTYYRL SCWVKTENVGTKTKGANISIEGSLDTSRDIRETSDNWEYLELYGKTSPNQETFTLTIG LGGYGNTNTGKIWIDDVEVVELESLPAGKTAINLDPKYTGGNQNTSENTGGKIFMIFI ALIFFLILLAVIFVIFFKDKMPGFNAKAAQTDKPAAKKNQKDDDEKWIKVKFDKIDFI IMGVMTLVYLCVALYNLGDFKVPTTSWEPTLPGEYFTVDLGKEATLSRIYYYCGLGSN KYNPFSKLRVEYLNENQEFEYLATIDKKELQDIFKWKYVDTAPVTTTQLKFIVDSTGG AFNEIAIVEQNSKEPLKNIKIIDSVLEDESKATIGNLFDEPDKFAFKPSYMNGMYFDE IYHARTAFEHIHRMSPYETTHPPLGKIFIALGILVFGMVPFGWRIVGTLFGVAMVPVM YMFGKKVFHDRFYAFCTAFLMMFDFMHFSQTRIATIDSYVTLFVILMYYHMYDYFINK SYNTTLKESLKPLFLSGLFFGLGAASKWIAIYGAAGLALLFFVNKGTEFWEYRKISTG KSKKKPLWIGDYPSNLGITIGACVLFFIIIPLVIYILSYIPYMLVPGDNKGITVFIEN SKHMFEYHSKLEAEHPYQSAWWEWPIMAKPMAFYFGSDLEPGMTSKIFTMGNPAVWWV GLLALLIVAIFALSKVNKNLVVLFTLAATTFGYVALPKTIFTETLKAQSAELCWAVIF FALIAILLVLSKLDTDILITSAVSSVAFGTILYLFKDIERGDAYLKSGNTQLIIWACL LICITLLFIGIYRYDKKMMVPLAGLIFQYVPWIAVPRIAFIYHYFSIVPFLILLIVYV IKKAADKHSGVKYFACVYLGIVMALFILFYPGLSGLEVPTSYMRYLKWFNTWYF" sig_peptide 12365..12445 /locus_tag="ClothDRAFT_2728" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 27" misc_feature 13259..13567 /locus_tag="ClothDRAFT_2728" /note="Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042" /db_xref="CDD:176621" misc_feature <13763..>14527 /locus_tag="ClothDRAFT_2728" /note="Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT; cl01961" /db_xref="CDD:186501" misc_feature <14909..15268 /locus_tag="ClothDRAFT_2728" /note="Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]; Region: PMT1; COG1928" /db_xref="CDD:32111" gene 15296..16270 /locus_tag="ClothDRAFT_2729" CDS 15296..16270 /locus_tag="ClothDRAFT_2729" /inference="protein motif:PFAM:PF00535" /note="PFAM: glycosyl transferase family 2; KEGG: geo:Geob_0317 glycosyl transferase family 2" /codon_start=1 /transl_table=11 /product="glycosyl transferase family 2" /protein_id="ZP_05430868.1" /db_xref="GI:256005923" /db_xref="InterPro:IPR001173" /translation="MSEKIVCSVVVPLYNEEEVILETYKRLKNVMESLNEPYEIIFVN DGSKDRTGIIANEICNKDKTVKLVDFARNFGHQTAITAGMDYSEGEAIVVIDADLQDP PELIPKMIEKWREGYDVVYGKRKERKGETFFKKFTAKVFYRFLRRMTDVDIPVDTGDF RLIDRKVCEALKLVNERNRYIRGIISWLGFKQTGIEFVREKRFAGETKYPLKKMLKFA ADAITSFSYKPLKLASYFGMLLSFCSFVYLLVVIWMKLFTDHVQQGWASTVAINLFFH GITLIILGIMGEYIGRIYDEAKGRPLYIVKQTRNFSEDKTDKITIRKK" misc_feature 15317..16219 /locus_tag="ClothDRAFT_2729" /note="undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714" /db_xref="CDD:182669" misc_feature 15320..15865 /locus_tag="ClothDRAFT_2729" /note="Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187" /db_xref="CDD:133030" misc_feature order(15329..15331,15335..15337,15587..15589) /locus_tag="ClothDRAFT_2729" /note="Ligand binding site; other site" /db_xref="CDD:133030" misc_feature order(15428..15430,15584..15589) /locus_tag="ClothDRAFT_2729" /note="Putative Catalytic site; other site" /db_xref="CDD:133030" misc_feature 15581..15589 /locus_tag="ClothDRAFT_2729" /note="DXD motif; other site" /db_xref="CDD:133030" ORIGIN 1 aaaaggtatt tttttcattt tcccgaacct tctcgacttt tgctgtctta aaggtgtcgg 61 tcgtgacagc ttttaaatta taacatcgaa aattgcataa agtcaagagg gtgttttttg 121 ctaaaaagca agtaataatc ctaatcatta ccccagaatt tattttatct tgttaattag 181 caaataatac gctttttttc acaatatttt ttacctttcc gcattctctg acttcttttt 241 cagttaaaac tcataccaaa cgattgtctt caacaattaa tttattgatt atcttcaata 301 attaacttat aattaaattc tttatttcac tctttattaa ttctttataa taacatatta 361 attttaacaa tactaatttt tatattaact tttatattaa ccgattatca ttctcagttt 421 gtttaaatct tcattataaa tttctttcag ctttacatta tatataatac ttgcaggatg 481 gtaaagcgga aacaggttaa actctgtccc caaaacctca accctggtca atgtaccatg 541 aacttcaccg atggaaatgc taaagtctcc atataccgac cttaaaggta cattgcccaa 601 agtaacgata tactcgggat taataatctc aatctccttc aataaatagc tcctgttttc 661 aagaatctca tttttggtcg caggtctgtt tgaaaccctg ttcgtttccg gttttacctt 721 tgagagcctg tatttgattg cattggttat atatatatcc tcccttttca gtcccagcac 781 gtccaaaaat tccgcaaggt ttttccccgc agcacctaca aaaggttttg atttcaaaac 841 ctcatctttc cccggagctt ctcctatcaa taccaatctg gaattaacat ttccgtctcc 901 caaaacaatt tctctttcct ggaattcttt cctgtataaa tcatataatt ctttcagccg 961 ttctgatttt gacatatgct atccaacctc tgttttacct ttttaaaatc ctcccacata 1021 agaaccttct ttgactcatc tctcaataat gccgcagggt gaaatgtggc tataatccaa 1081 tatccctttc tctcaatcca ctggcctctg acatttgtaa tctttgcatt cctgtcaata 1141 atatatttca ttgccgttgc ccccaaacat actattatac ggggcttgac aagcacaagc 1201 tggtttctca gatacggcag gcacatttca gcttcgtcat ccgtaggaac tctgttgccc 1261 ggaggcctgc attttacgat atttgctata tagtacatgt cctcttttat tctcattgct 1321 ttcagcaaca aatccagaag ctttccagcc ggccccacaa acggaagtcc ctgcaaatcc 1381 tcctgttcgc cgggaccctc ccccacaagc atcatgggag cgtttatgtt tccgcgccca 1441 atcacaatat tggttcttgt cttgctcaaa ccgcactttg tacagtttga acatactttt 1501 atcagctctt cccaactata cataccattt atacccctgt tttgtcaggt ccccatatca 1561 ctttgtgaag ctgaacctga aatcttgcat caagcttatc ctccagtatc catttaacta 1621 taccggagta atcaattttt ccatataccg gagaaaaagt cacagttcct tttttgtgat 1681 attttgaaat tatatttttg gcccaatcgt aatcaactct gcttcctatc acaaacttta 1741 tttcatcatt gtccctcagc aaatcaaaat tttcaaagag catttggtcg ctgcatcccg 1801 atgacggtac tttcatgtcc ataacataag aatgcttcgg atttttaagc tcaacacttt 1861 taagacttac agagccgttg gtctctatag tcacaatata gtcatcaagg aactcgagca 1921 attgacccaa ctctttttgc aaaaggggtt ctcctcctgt aagacatacc cttttataat 1981 gaagcttttt tatctcttca aatacttcag agggagtcat gtcttctccc tctttatagg 2041 cataccttgt gtcacagtag ctgcatcgaa gattgcagcc ggtaaagcgg acgaatacag 2101 tcggaaaacc tgcggacaaa ctctccccct gaatacttaa aaatatctca ttcactttca 2161 tgttcttttc ccctttgaaa acaaagctac tccatatcat tcctgtcaat ggttatatag 2221 ctggtgggag tttcccaaag caccagtttt tccaaggtgc accgggtatt ttgtacctgc 2281 tttgaaatct cttcccataa ccaaagtcct atcatttcac aggtcggatt aaaatcaaac 2341 acatcattaa ggtacttgtg atccaccttt tccagtacct cattttctat tatagcttcc 2401 aaatcatgaa aatccattac caagccgttt tcatcaggaa gacctttcaa tgtaatctcc 2461 aatttgtaag tatgcccgtg gatgttcctg catttgccgt tatagtctat caggtgatgc 2521 gcgctgtcaa aggtaaacag ctttgttata gaaactttcc caattttcat gactgcaatc 2581 ctttcaaatg aatttatatt tttaagttct ctccatatat tctatggtat ccacaattcc 2641 ggcctcttta aatcccttca gtcttaaaac acagctgtca caaacaccgc atgctttttc 2701 tccgcccctg taacaggttg tggtcaaatg aaggggggca ttgttttcac acgccagctt 2761 tataatttcg gctttggaaa gatttattaa cggagtaatt attttaaccg gttttccatt 2821 cactccgctc ttcgttccca ggtttattgc tttttgaaaa gcctcgataa attccggcct 2881 gcaatccgga tagccgctgt aatcaacagc attaacgccg ataaaaatgg cttcggcatc 2941 caccacctcg gcatacccta ctgcatagct taaaaaaatt atgtttcttg caggcacata 3001 cgtaacaggt atggtcggaa gccctttata atcgggaaca tctatgttca tatctgtcaa 3061 agcgcttcct cccacatttc ctatcttcac gattttgtgc tcttttagtt taaaatactt 3121 aactacctgt tttgcactct caagctcctt tctgtttctc tgcccgtaat caaaggacag 3181 aggataaacc tcatagcctt ccgccaaggc aactgacaaa caagtggtac tgtccagtcc 3241 gccggacaac aatacaacag ctcttctcat actatcctct ccaataacat tagaatttaa 3301 gttaaaatga acatttaatt aatatttaca aaatgacatt tggtttttac gtcaaagcaa 3361 cactgcaaat gcaagttcca acaaaatcta agttcaaact cagtttgtcc aatacagcaa 3421 tgcatcaaca cagcaataga gcaacaaaaa ccaatgcaat ttttagtaca attttcacaa 3481 aatattgatg caacttataa aaccaattta tataagtata ccagtatatt aatgattttt 3541 caaaaagtat tcggcctcag tttattttgc cagtttcatt ttctcaatcc tgaacgcaca 3601 gcagccgatg gcaccgttca gctggggcct ttcaggtatg acaacccttt taaaatcaag 3661 ctcggatttt ataaattcca gcaaagcttt attttgggca acaccgccgc ataccaccaa 3721 attctcatga ggaaatcttt caattatcgg tttaatcctt ttaaaaaggg agtagttcac 3781 ccctgcggca agctccctga tgccgtaccc ttcggatatt tttccgataa gctccgattc 3841 accgaaaaca gcgcaagtag agttaagctc caccggattt tcatggtatc ctgcaagctc 3901 ttcaagaccg ataccgagaa tgtttgccat gttttcaaga tatcttccgc aggatgcggc 3961 acatttgtcg ttcaaaacca tgtccgccat tttgccgttc ctgaccgata taactttact 4021 gtcctggccg cctatgtcaa gaagcgtgaa gtcatcaagc ccggtctgcc acaccgcgcc 4081 gtaagtgtga gcttttaact ccagtatcac cgttgcattt tccacattta cattatttct 4141 tccgtagcct gtgcttacca cgctgtcaaa gtatcctata tcaagttttt caaaatcaac 4201 gttgattttt tggtttacat tggagcaaaa gtcacggtaa aaagttgcag tgtcgtaaat 4261 catgctgttt acaaaattgc cgtcttcaaa aacgaccagt ttaaccgttc tgctccccaa 4321 atctattccc aataccctca taattcacct tttctaatat attttatttt ttcaatagag 4381 attattcatt caaatttaaa ttcactcatc cagcatatca ataaacgctt caatacgaag 4441 ccttgttctc tggtcaagtt ttccgggtct gtctccttca agggtaagaa ccgggacacc 4501 aagttccttc cttattataa tgtcttcaat acctctaaag caaaatgcct gagtgtagtg 4561 tataacccca tcaatctttc tttttttcac ctggaccgtt atatcttcaa gtctgcctct 4621 tataccgtac gggtaggtaa atctcctgta ttcttccaca atatcttcaa tgccaaccga 4681 atctgccatt gtaaactgtc tctgcacctc attatatacc accctggcat caagagattc 4741 aataaattca tatatatctg cgttaatagg cggaactcct atatacccta ttcttttact 4801 ctctgttttc ggctcccttt tttcaatgga ggaaatagca tcttccagct cgcggccaaa 4861 ggtaacataa tccccgttaa aatcactgct tgaaacctgc catatgtgat tttcaaatcc 4921 tccggccttg ttgtgcttcc atgtcaattc atccaaataa gcaagtctta gtctaatctt 4981 gtccaattcc tttttaactt tcaaacactc ttcataactg accccaaaat gactgcaaaa 5041 cctgtcaatt tcctttttca accggtcgta acttcgggaa ctgggatatg aaaactggaa 5101 acattgcacg cccttcagtt ccaaaacctc cacaagggct ttcgcattag agcagtcacc 5161 ttcaacaaca cctatcagct catctattcc tcccatatct gccacagcag aataaatacc 5221 ttttatccat gcacagatat ttctgggaaa acctgtattt tcagccactt ctatcaactt 5281 tcccggatta tcatcggtaa taaaaacatt atttaaatca acaggtctgt accctgccgc 5341 aaatatcacc tcaacgggta cgcttgttgt aaaacctata tttttcaaac caactaacac 5401 ctcaaatcat ttcttcccat aaaattataa tacataaatt aatggtttta agcaattata 5461 tattaagccc aacgaaatga ctacaaaaaa tcagcctttt cagctgattt ttaaaattca 5521 ctttgttacc actaattgga gtaatagaaa ttttgttcta taagttcttt tgttttcttt 5581 ttgtcatata tataaaacca ctgtcctccg atatatctgg aatatcccgg cagtgtgtac 5641 ccattgattt cgggggtttt aatatttttt atgtctttaa taaaataacg tatgtctcca 5701 atctcaatgt ttgtcctcat attttttttc aaggtgtaaa aaatttcatc cgccttaagt 5761 aaatatttta attttagctt ttgattcaca aactccctca taaaaagctg ctgcatttta 5821 atccgtccaa gatccccatc ctcataacct tccccgttgt ggttgccttt gcggtatctt 5881 acaaattgct ccgctttttt gccgtccaat acttgctttc ccttctttaa gtgaatgtgg 5941 agattctgat acggatcgtc atagtccatg tcaaagggta cgtttatttc cacacccccc 6001 aacgtgtcaa cgatttccct aaagcccttg aaattcaaag taacatagta atctacggga 6061 aggccggtta tatcctccac catgtcaatt accatttttt ctccgccttt tccaataagg 6121 gcgtttatct tcatgtattt gccgttgact ttcacccggg tatccctagc aatggacaat 6181 atgttcattt tgttttcatc agggttgtag tttataagag caatgacatc ggaccttttc 6241 tcatcatcat caagccccag gacaaggaca tttatatatg agtttaaggt ctttcgccca 6301 tcttcccggt caattttcca ttttacaatc tccacaggat cgtacttgtc gtcagactct 6361 gttccattgt atttctcttt tgcaagcaaa agagtgtata ttccttgtat aaataaaacc 6421 agtgaaaaaa ctacacatat atacagaata ctttttctaa aattcatact tcacccgtgt 6481 ttaaaataca taagcgttat aaaaaaccgt attcttagta tatgtgtata acatttttta 6541 atacaacgga cagagtcaaa tcaaaaaata aatcctgcta aaatttcaaa tttttaaatc 6601 tttccacagc ctcaagagta ttctccctgc ttccgaaagc ggttaaccgg aaatatcctt 6661 ctccgctcgg tccgaatcct gaaccgggtg ttccgacaac atttatttct tttagcatga 6721 tatcaaaaaa ttcccatgaa cttatgccat ccggagtctt aagccagata tacggagcat 6781 ttactcctcc aaatacggta agcccgatat cctccaaacc ttgtttgatt atttttgcat 6841 tttccatgta atagtctatg gtttctttag tctgtttttg tccctccggg gtataaaccg 6901 ccgccgctgc ccgctgtata atatacggaa caccgttgaa ttttgttgtc tgtcttctgt 6961 tccaaaggct gttgagctga tgcgcttctc cgtttttggt ataagccaca acctttttgg 7021 gaactacggt atacgcacac cttgttccgg taaaacctgc cgtcttggaa aagcttctaa 7081 actcaattgc cacctcatct gctccctcaa cctcataaat gctgtggggc acatctttct 7141 cacggatata cgcctcgtat gccgagtcaa acagtattat cgcgcggttt tcccttgcat 7201 agtcgaccca ctttttaagt tcttccctag acaaggtcat tcccgtcgga ttatttggga 7261 aacaaaggta aataatatcc actttctctt ttggaagttc aggaatgaaa ttgttttcgg 7321 cagtacacgg aagataggtt atattctcaa aataaccatt cgcaagatac tttccggtcc 7381 ttcctgccat aacattgctg tcaacataaa caggatatac agggtcggta acggcaactt 7441 tgttgtccag gccaaatatc tcctggaaat ttccagtatc acttttcgcc ccgtcgctta 7501 caaaaacctc gtcctcatca agcctgattc cccggggcat atagtcatat tcaattattt 7561 tgctgactaa gaagctataa ccttgctccg gtccgtatcc tttaaaagtc tcctcttttg 7621 ccatttcgtc caccgctttg tgcaaagcgt caataactgc cggcgccaac ggctttgtaa 7681 catctccaat acccagccgt attatttttg cattgggatt ttcctttctg aaattgtcca 7741 ctctcctcgc aatttcagaa aaaaggtagc ttcccggaag cttaagataa ttttcattaa 7801 taaaagccat agacaacctc cattctattt ttttctttca aaagtcacca tgccaaaaat 7861 caaattgtat gattttaggg acttgaacct gtcaaaggtt taaagttcgt tcaagtcaac 7921 ttcaccttca aatactttaa cagccggacc cgtcatatag acatgattgt tattctcatt 7981 ccattcaata ataaggtccc cacccaaaag ttttacagtt gccttccttt cactgacacc 8041 gttcagcacc gatgccacca gcacggcaca ggcaccggtt ccgcatgcca aagtctcccc 8101 cgcgcctctt tcccaaaccc gcattttcag ggtggttctg tctatcactt ccacaaactc 8161 ggcatttatt ctttttggaa agagaggatg atgttccatt ttaggaccga ttttttcaag 8221 aggaaaaatg tccacattct tgacatagga tactgcatgg ggatttccca ttgacacaca 8281 tgtgacttta aattcttttc cgtctatttc aacaggctcc gtcctgaaaa tctccttgtc 8341 actgttcacc ggtatatttt ccggcttcaa tataggttcc cccatatcaa cttttacaag 8401 tttggccttt ccatcttgca cagtcagttc aagaaccttt attcctgcca gcgtctctac 8461 tcttataaca tttttattcg tcattccccg gtcaaataca tatttcccca cacatcttat 8521 cgcatttccg cacatttcgg cctcagaacc gtccgaattg aacattctca tcttaaagtc 8581 cgccctctct gaaggcatta tcagtacaag tccgtcggaa ccaatgccaa aatgcctgtc 8641 gctgaccttt ttcgcaactt cggaagggtt ttcgacagtc tcttcaaagc aattaacata 8701 tatatagtca ttccccagcc catgcatttt ggtaaacctc attttgcaac ctccaaattt 8761 aaaacttgca tttttctttg tactcattat aacatacatt tcttacatga caatatgaaa 8821 aaagaatttt ttatgcattt aatattgttt ttgaagcaaa atataaatat actcaagcac 8881 tatacaaatt tagtgtgagt agtttaagac ttattcataa atcttcacag cggggtggat 8941 aaatgaaaat tctcgttata attcctgcat ataacgaaga agccacaata aaaaacgtta 9001 tccaacgaat aaaacttaaa atgccgcaag ctgacatcct cgtcgtaaat gacggttcaa 9061 aggacaatac atcccggaaa gcaaaaacag caggagccaa agtaatagac ttgccctaca 9121 accttggaat aggaggtgca atgcaaaccg gatacttata tgccaaggaa aacggatatg 9181 atattgccgt tcaggtggat ggggacgggc aacacgaccc ttcctatata aaggagctga 9241 ttgagcccat cataaacaat tcggccgatg tggttgtcgg ttcccgctac atcagcaaaa 9301 ccaattacaa gtcatcggta tttagaagaa tgggaatgat ttttttctca tttttggtaa 9361 gtacactgac aaaccagaaa ttcaaggaca caacctcggg tttcagggct gtaaacaaag 9421 aagtcataaa ttatttttcc aaccattatc ccgtggatta tcccgaagtt gacgtattga 9481 taaggctcaa aaaaaggaat ttcagaattg cagaacttcc ggtggaaatg tataagcgcc 9541 agggaggcaa atcttccatc acaacctttc gttcattata ttacatgcta aaggtaagtc 9601 ttgccattat cattggtaca ttacggtcgt ccgaagagta gagaggtggt ataaatggtt 9661 ataaatgtat attccctttc cataatgttc agcgtgttct ttttattgct cgtaatcgaa 9721 ttggtaagaa aaaacaagct tcaggagcgc tactgcctgc tgtggatact aatgagcatt 9781 atcctccttg tattgtccag cactccggtt atcatagaaa ctgtttccgc atggctcgac 9841 ataaaaaatc ctccttccct cttgtttttg ttcggtcttg gatatttgat tttatacaac 9901 cttgccacta cggtaacggt gtcaaaacag tcggaaagaa taacccgtct cacccaggaa 9961 atcgcccttc ttagacaaaa aatcaccgac atgaactcaa agtaaaataa aaattgctta 10021 ttacccataa tactgctata atatagacat atacttctat attttttgtt tttaggaggt 10081 ttatatttat tttttggaat ttatgttgta ttttgggtta ttaggagaca attatgggta 10141 catatttgat ttcagttgct atcccggtat acaatgaagc aaaacaaatt tatgaaaata 10201 taaatataat tcacaaaatt ttgacagaaa acaacattaa tcatgaattt atccttgtgg 10261 acgacgggtc ccgggacaac acgtgggaag agcttaaaag gctttctgtg gatcttccga 10321 atgtcctggc catcagactt agcaggaatt tcggcaagga agccgctctt tgtgcggcgt 10381 tggaagccgc ccacggagat gcttgtgtgg ttatggattc cgaccttcag catccgccgg 10441 aaatcattcc ccaaatggtg cgaatgtgga gagaagaagg ttatgacgtc gtggaaggtg 10501 taaagtcttc aaggggtaag gaaagtatta caaacaaggt gggtgcccat ttattctact 10561 caatattgaa aaatttgtcg ggctttaact tagacggcgc atccgatttc aaacttcttg 10621 attcgaaagt ggtggcttca tggcgcatca tgccggagcg caacaccttt tttcagagga 10681 atgtccgcct ggcttggata caaaagagcc tccattccct tcgaagtggt ggaaagaagg 10741 gaaggaaaat caaaatggtc cactttaaaa cttttcaaac tggcaataac cgcaataaca 10801 tctttttcgt cgcttccgct tcatttggtt acattaatgg gcatgttgtt tctcttctgc 10861 tccattataa tgggcattta caccctgtat atgaagttca gaggtttggc cgtaagcggt 10921 ttcaccactg tcattcttct gcttttgata atcgggagca cattaatgat aagtctcggc 10981 attataggaa cctacattgc aaaaatattt gacgaggtca agttccgtcc gcggtacata 11041 ataagcgaaa aagcgacaag taaaaaaaca gaacatgaaa atatcggcac aaacagttaa 11101 cattgccgcc gcttaaaaat atgccgaaac acatttataa aaatttacat ttataaaaat 11161 ttacatttat aaaaatttgt tttttaattt taattattat attatatatt tttgtggagg 11221 tcgataaaaa atgttcaaaa aagtggttgc aatttttacc acaatggttt tactaatagc 11281 tcttacagtt gtttcctgtg ctgaaaatac caattacatc tttaacggtt cttttgaact 11341 gcttatagac ggcgaaccct caaactggat gagggaagct tacgacaaat ctcccggcgc 11401 atcaaatttt agagttgaaa ccgaaggcgc caagttcggg gaaaaatacg tcaccattat 11461 caacaacaaa ttaaatgaca gcagatattc acaaatcgtc ctggttgaag aaaacaagaa 11521 gtacaagctg tcctgttaca taaaaactga aaacgtaagt gaagaaggta aaggcgcaaa 11581 tctttccgtg gcagaacaga cagtaacatc aaagcgaatc aagggaacaa ccgacgattg 11641 ggaatacgtc gaattgtatg ttatcaccga aagcggtgtt gacagaataa aagttaccgt 11701 tggactcggc ggatacagtg gaatgagtac gggaaaagca tctttcgaca acgtgacgat 11761 ggaggaggtt gaaacaatac ccgaaggtgc gccccgtgct gtagtaaaag cccaaaacac 11821 taaaaaaagc agtaataatt ccaacaatac caacaacacc aagagctctt catctcaaaa 11881 caacgaaaac aaaaatgaat taggcaaggt tgttttggta atgttgattg tgggagctat 11941 tgccgtggga gttgctgttt acaatacctt cagatcaaac aaaaaagttt cgggcaacca 12001 aggcaatgcc agcaacaata ccggtacaaa taccaacatg acagaatctg ccgccaataa 12061 agaatccgcg ggcaataagg aattttctga caacaatgaa tcttcccaca gcaaagaaga 12121 ttcttctgat aattctgatt ctgataataa agaatcttct gattaattaa agatgacaaa 12181 aaagatgaca aaaattaaaa cttttatctt tcaggatgtc agaaaggcat caggtatgct 12241 tcaaaaaaac aaaagaaaaa ataacattgt tgacaacata aatgcaaaag cctgattatc 12301 agcctttctg catttatgtt taaatatttt taaatttatg aatttttttg ggggtgctta 12361 caaagtgtcg aaaaaacttt ttaaggtctg ccttatatta ttaatctcaa ttcagttcat 12421 tttttcttct cccgtgtttg ctgaaagtga aaatcttgta aaaaaccccg ggtttgaaga 12481 aggaaatgat gagagtgtat atttttggca gacccactgt tgggaaaaag ctgaaggagt 12541 tacagaattt tttattgatg aatccgtata ccattccgga ggcaaaagtg cgtgcatagt 12601 taaccattct gaaaatgatt ccagatacat gcagccaatc aaggtaaaag gagatacata 12661 ttatagattg tcctgttggg taaagacaga aaatgtcgga accaaaacca aaggagccaa 12721 catctccatt gaaggcagcc tggatacttc cagggatatc cgtgaaacaa gcgataactg 12781 ggaatatctc gagctatatg gtaagaccag tccaaaccag gaaaccttta ctcttaccat 12841 aggtcttggc ggatacggca ataccaatac cggtaaaata tggattgatg acgttgaagt 12901 tgtcgagctt gaaagtcttc ctgccggcaa aacagccatc aaccttgatc cgaagtatac 12961 aggaggaaat cagaacacgt ctgaaaatac cggcggtaaa atatttatga tttttatcgc 13021 actaattttc tttctcattt tgcttgccgt gatatttgtc atattcttta aagacaaaat 13081 gcccggcttt aacgccaaag cggcgcagac cgacaagccg gcagccaaaa aaaatcagaa 13141 agatgatgat gagaaatgga taaaagtcaa atttgacaaa attgatttta tcataatggg 13201 cgttatgacc cttgtttatc tctgcgttgc tttgtacaac ctcggagatt ttaaagttcc 13261 caccacttca tgggaaccaa ctctgcccgg tgaatatttt accgtagatc ttggcaaaga 13321 agccactctg tcaagaatat actactactg cggactgggc agtaacaaat acaatccttt 13381 ttccaaatta agagttgaat atcttaatga aaaccaggaa tttgaatatc ttgcaactat 13441 tgataagaaa gagcttcaag acatctttaa atggaaatac gttgacaccg caccggtaac 13501 caccacacaa ctcaagttta ttgtagactc caccggaggc gcgttcaatg aaatagccat 13561 agttgaacaa aacagcaaag agcctttgaa aaatatcaaa attattgaca gcgtactgga 13621 agatgaaagc aaggctacaa taggaaatct ttttgatgaa ccggacaagt ttgcattcaa 13681 gccttcctac atgaacggaa tgtatttcga tgaaatttat catgcaagga cggctttcga 13741 acacattcac agaatgtctc cttatgaaac aacccaccca cctctcggga aaatcttcat 13801 agcattgggt atcctcgtat ttggaatggt gcctttcggc tggagaatag tcggcactct 13861 gtttggtgtt gccatggtgc cggtaatgta tatgttcgga aaaaaggtct tccatgacag 13921 attttatgcg ttttgcactg catttttaat gatgtttgac tttatgcatt tcagtcagac 13981 gcgaatagca acaatagaca gctatgtaac tttatttgtc atactcatgt attaccacat 14041 gtatgactac tttataaaca aatcctacaa cacaaccctt aaggaatctt tgaagccttt 14101 gttcctaagc ggactgttct ttgggttggg cgccgccagc aagtggattg caatttacgg 14161 agccgccgga cttgcccttc tgttctttgt aaacaaggga accgagtttt gggaatatag 14221 aaagatatca accggcaaat ccaaaaagaa acctctctgg attggcgatt atccttcaaa 14281 cttaggcatt acgataggag cgtgtgtttt attctttatt ataattcctc tggtaattta 14341 catcctgtca tatattcctt atatgctggt acccggggac aacaaaggaa tcactgtatt 14401 tattgaaaac tccaagcaca tgtttgaata tcactcaaaa ctggaagcgg aacacccgta 14461 ccagtccgca tggtgggaat ggcctattat ggcaaaaccc atggcgttct acttcggtag 14521 cgaccttgaa cccggtatga cttcaaaaat atttacaatg ggaaatccgg ccgtatggtg 14581 ggttggactt ctggctttat tgatagttgc aatatttgcc ctttcaaaag tcaacaaaaa 14641 tcttgtcgta ctgtttactt tggcagcaac caccttcgga tatgttgcac tgcctaaaac 14701 aatcttcaca gaaactctga aagcccaaag cgccgaatta tgctgggccg taatcttctt 14761 cgcattaatt gctatcctgc tggttctgtc aaagctggat acggacattt taataaccag 14821 cgctgtttcc tcggttgcat ttggaacaat actttacctc tttaaagata tcgaaagagg 14881 agatgcatac ttaaagagcg gcaatacaca gcttattata tgggcctgtc ttttaatatg 14941 tataacattg ctgtttatcg gaatatacag gtacgacaaa aaaatgatgg tgcctttggc 15001 cggacttata ttccagtacg taccatggat tgccgtcccc agaatagcat ttatatatca 15061 ctatttctcc attgtaccgt ttttaatact gttaattgtt tatgtcatta aaaaagctgc 15121 cgataaacat agtggcgtaa aatatttcgc atgtgtttac cttggaattg ttatggctct 15181 gtttatactc ttctatcctg gattgtcagg acttgaagta cctacatctt atatgagata 15241 tcttaaatgg tttaacacat ggtatttcta aacaaggaaa ttggaggcaa aagaaatgtc 15301 ggagaaaatt gtatgttcag ttgttgtacc tctttacaac gaagaagagg taattctgga 15361 aacctacaaa aggcttaaaa atgtaatgga atcactgaat gagccttatg aaataatatt 15421 tgtcaacgat ggaagcaaag acagaacagg aattatcgcc aatgaaatat gtaacaagga 15481 taaaaccgta aagctggtgg actttgcaag aaatttcggc catcaaaccg caataaccgc 15541 cggaatggat tattctgaag gtgaagccat agttgtcatt gatgcagacc ttcaggaccc 15601 tccggagctt attcccaaaa tgattgaaaa atggcgcgaa ggctatgatg ttgtatacgg 15661 aaaaagaaaa gaaagaaaag gcgaaacttt ctttaaaaag tttacggcaa aggtattcta 15721 ccgcttctta agaagaatga ccgatgtaga tattcctgtt gacacaggcg acttcagact 15781 catagaccgg aaggtctgtg aagctctcaa gctggttaat gagcgcaaca gatatatacg 15841 cggcataata agctggcttg gctttaaaca aacaggaatt gagtttgtaa gggaaaaacg 15901 ctttgccggc gaaacaaagt atcccttaaa gaaaatgctg aagtttgccg ccgatgccat 15961 tacatcattc tcctataaac ctttgaagct ggcgtcatac tttggtatgc tgctctcatt 16021 ttgcagtttc gtatatctgc ttgtggttat ctggatgaag ctttttacgg accatgtaca 16081 acaaggttgg gcgtcaaccg tcgcaatcaa cctctttttc cacggcatta ctcttatcat 16141 tttaggtatc atgggagagt atataggaag aatttatgac gaagccaaag gaagaccttt 16201 atatatcgta aaacagacca gaaacttctc tgaagacaaa accgacaaga taaccataag 16261 aaaaaaataa tcacaaagga tagtctcaaa gcaaggttta taaagttcgt aacaataaaa 16321 taataaacca aaaacaataa atcaataagc caccaataaa acatcccctg aataaaagct 16381 gagaacagtg ttctcagctt ctattcaggg gggatttgtt tttggataaa aaaaaataac 16441 agtt //