LOCUS NZ_ACVX01000057 12002 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00047, whole genome shotgun sequence. ACCESSION NZ_ACVX01000057 NZ_ACVX00000000 VERSION NZ_ACVX01000057.1 GI:256006039 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000057. FEATURES Location/Qualifiers source 1..12002 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene complement(84..1013) /locus_tag="ClothDRAFT_2837" CDS complement(84..1013) /locus_tag="ClothDRAFT_2837" /inference="protein motif:PFAM:PF01594" /note="PFAM: protein of unknown function UPF0118; KEGG: sme:SMc00616 putative permease protein" /codon_start=1 /transl_table=11 /product="protein of unknown function UPF0118" /protein_id="ZP_05430976.1" /db_xref="GI:256006040" /db_xref="InterPro:IPR002549" /translation="MNKRLFKNRLKVLVRGIAITVTYLVVLLLITLIISFIIPELIKS IQVFLSNMGAYIDNFRDLTNELSELLGLERIDLSSLDKLILEYTNRLGSSLTELMPKI ISITTGVLSFFATLVITVVFSIYILAGKERLIGQCKKVFSTYLPECLYKKGAYVYRVV VDVFNKYIYGQLAEAFILGSLCFIGMVIFRFEYALLISVLIAVTALVPYFGAYIGGFC AFMLLLMISPTKAIWFLVYLVVLQQLENNLIYPRVVGSSLGLPGIWVVLAAIVGAGVG GPIGVLTGVPIATVLFTLLRNDVLRRSGKQNVK" misc_feature complement(222..>881) /locus_tag="ClothDRAFT_2837" /note="Domain of unknown function DUF20; Region: UPF0118; cl00465" /db_xref="CDD:186015" gene complement(1006..1203) /locus_tag="ClothDRAFT_2838" CDS complement(1006..1203) /locus_tag="ClothDRAFT_2838" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430977.1" /db_xref="GI:256006041" /translation="MSDKMTRNLIIVITYAVALVLIVINFVPIMRAVWKFIVLFKPFF MGIAVAFVLNRPCMAVERFFE" gene 1535..2476 /locus_tag="ClothDRAFT_2839" CDS 1535..2476 /locus_tag="ClothDRAFT_2839" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430978.1" /db_xref="GI:256006042" /translation="MEENLEGKIEKNSEANLETPVEIESTAETPGEIHSQNNPENNSV STFTKVHTTVSFIVMVLINFLANTIPLNKMTTGEISDLYPNLFAPAGMTFSIWRIIYL LLGAYTIYQFGIFKKKDGVFSKNLIEHLGIFFSISSIANTAWIFAWHYHAIGMSLVLT AVILACLIYINIKIRKANLETLEKLFIKLPFSIYFGWITITAIANTIAFLSSIGWNRF GISEPLWTSLVLIFTLLICGIITFKNQDFIYGLPVIWAFIGILIRHTSENGFEGKYPG IIILLIVIIILLLITDVYILVSDKEKLKSFKLFKRLK" gene 2835..4958 /locus_tag="ClothDRAFT_2840" CDS 2835..4958 /locus_tag="ClothDRAFT_2840" /EC_number="3.6.1.1" /inference="protein motif:PRIAM:3.6.1.1" /note="PFAM: Inorganic H pyrophosphatase; KEGG: pca:Pcar_2001 membrane-bound proton-translocating pyrophosphatase" /codon_start=1 /transl_table=11 /product="Inorganic diphosphatase" /protein_id="ZP_05430979.1" /db_xref="GI:256006043" /db_xref="InterPro:IPR004131" /translation="MIQITTQTIQIVAILISLLSLGVAAWLYSWVKSQPSSNARIAEI GGYIRQGANTFLRREYLILARFTAIAAVLILIFLPHPIWSGNITQNIWMAVSYIFGTV LSALAGKIGIQIATIANIKSAEAAQKGVKPAFMTGFRGGAVMGMAVVGTSLLGVTLVL LIVGDASAVLGFSFGASSLALFAKAGGGIFTKTADISADLVGKVELGLEEDDPRNPAV IADNVGDNVGDVAGMGADLFDSNVASMAAALVMATALGGPDSKNVAMVFAYAAIGLLS SVIGVATARIGKNGDPGKALNSSTYVTTAIFAVLTALSTYIFNFEWRIWGATAIGLIV GTIIGLTSDYFTNDAKPPVRAVANASKSGPAFTILSGFSYGLLSALPSLIGIAVTALI SYYICEPLGSGYGMFGISMSALGMLSIVGMIISNDAYGPIVDNARGLAEMGGFGEKVI AIADELDSAGNTVKAVTKGFSISAAGLTVISLLGAFMSEVNTAASELGVQGIANFDIM NPTVFFGLIVGVAIPAVFSAMLMLGVDKNAQRMVAEIHRQWDTIPGLKEGKENAKPDY DKCIDIATTGSLKELIPAGLVAIFSTILVGFIGGASAIGGFLTGNITSGLLLALLMSN AGGLWDNSKKYVEAGNCGGKGSTAHKAAVVGDTVGDPFKDTAGPSINTQITVVSLVSS LLASLFLNVLNFLKKRNGFALISVA" sig_peptide 2835..2912 /locus_tag="ClothDRAFT_2840" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.934) with cleavage site probability 0.638 at residue 26" misc_feature 2883..4856 /locus_tag="ClothDRAFT_2840" /note="Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030" /db_xref="CDD:145921" misc_feature 2886..4856 /locus_tag="ClothDRAFT_2840" /note="Inorganic pyrophosphatase [Energy production and conversion]; Region: OVP1; cl11452" /db_xref="CDD:187048" gene 5285..6019 /locus_tag="ClothDRAFT_2841" CDS 5285..6019 /locus_tag="ClothDRAFT_2841" /inference="protein motif:PFAM:PF03591" /note="PFAM: AzlC family protein; KEGG: dds:Ddes_0523 AzlC family protein" /codon_start=1 /transl_table=11 /product="AzlC family protein" /protein_id="ZP_05430980.1" /db_xref="GI:256006044" /db_xref="InterPro:IPR011606" /translation="MNKSQTKINDFVYGFKKGTPILLGYIPVAFTFGLMAVGGGLHPL MAVFISLTNLTSAGQFAGTNLIIQGAGYLEIALTTFVINIRYMLMSLSLSQKIDPKIT LWQRLVFGFGITDETFSVASMEKGRLSYFYMLGLIAGPIFGWSFGTALGAFTSSALPE SLSNAMGIALFAMFIAIIVPPAKKSRPVLMIVLISVAINLALKYIPLFSFISSGFAII ISTVLGAGIGAAIWPIKEENPVLKEE" misc_feature 5342..5761 /locus_tag="ClothDRAFT_2841" /note="AzlC protein; Region: AzlC; cl00570" /db_xref="CDD:153863" gene 6024..6326 /locus_tag="ClothDRAFT_2842" CDS 6024..6326 /locus_tag="ClothDRAFT_2842" /inference="protein motif:PFAM:PF05437" /note="PFAM: branched-chain amino acid transport; KEGG: dds:Ddes_0522 branched-chain amino acid transport" /codon_start=1 /transl_table=11 /product="branched-chain amino acid transport" /protein_id="ZP_05430981.1" /db_xref="GI:256006045" /db_xref="InterPro:IPR008407" /translation="MPYALIAALLMALVTYLPRVLPIAVFRKEIKSTYIKSFLRYVPY AVLGALTFPDIFSSTNNYGTAICGTVVALILAYMEKSLFIVALGAILTVYVTGLFL" misc_feature 6036..6308 /locus_tag="ClothDRAFT_2842" /note="Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735" /db_xref="CDD:153963" gene complement(6307..7635) /locus_tag="ClothDRAFT_2843" CDS complement(6307..7635) /locus_tag="ClothDRAFT_2843" /inference="protein motif:PFAM:PF00232" /note="PFAM: glycoside hydrolase family 1; KEGG: scl:sce4196 beta-glucosidase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 1" /protein_id="ZP_05430982.1" /db_xref="GI:256006046" /db_xref="InterPro:IPR001360" /translation="MVTFKLNDEFMFGTATASTQIEGGDTGNTWYKWCQEGRIKDSSS CITACDHWNRVEEDTELLKNLGVQTHRMSLEWSRIEPSRGKFSDDAMKHYRDEIKLLV ENNIKPLVTLHHFSEPIWFHEMGGWKKTGNADIFIEYVKYVVENLGDLVSDWVTFNEP NVYVDFGYVIGIFPPGERSLSEGLKVTAELINTHVKLYRLIHRIRRERKFAGRTMVGT AMHLRIFDGISSTGKMIAKVVDYLFNEMFMEGMTTGHMMFPLSKKGSSHKKGRYADFL GINYYTRNIVEFVFDPSLYFHELVCDKDLTKSDLGWDIYPEGIYKVCKRYYKKYKLPI YITENGISDKNDTKRPSFIASHLAYIAKAIKEGIPIERYYYWTLMDNFEWLEGESTDF GLYDCNFRTQERIPRKSVRLYEQICRRKELTAEMIEDFKKYSGITIETIR" misc_feature complement(6397..7614) /locus_tag="ClothDRAFT_2843" /note="Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046" /db_xref="CDD:186308" gene complement(7666..8565) /locus_tag="ClothDRAFT_2844" CDS complement(7666..8565) /locus_tag="ClothDRAFT_2844" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430983.1" /db_xref="GI:256006047" /translation="MYEFKRLSEVFESAEEIPFDDFSKIIIMSDCHRGDGSWADNFSK NKNIYYAALTYYYRNNFTYIELGDGDELWENDNICDIISEHRDVFSLLTRFIDEGRAY FIYGNHDIEKKKYALRTLRERKSFKYLEDGDKRNVAAFFKTKVHEGLILRHRVTGDKI FLVHGHQADFANDKLWRVSKFFVRYLWRPLELLGIRDPNSASKNDRKKTVIANKIVDW VKSNNQMIIAGHTHRAVFPAVGQPPYFNDGCCVHPYGITGIEIVHGKIALVKWSVKTK DDGTLYVGRDEIEKPVKLKEYFR" misc_feature complement(7816..8490) /locus_tag="ClothDRAFT_2844" /note="Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398" /db_xref="CDD:163641" misc_feature complement(order(7870..7872,7876..7878,8074..8076, 8242..8247,8362..8364,8470..8472,8476..8478)) /locus_tag="ClothDRAFT_2844" /note="putative active site; other site" /db_xref="CDD:163641" misc_feature complement(order(7870..7872,7876..7878,8074..8076, 8245..8247,8362..8364,8470..8472,8476..8478)) /locus_tag="ClothDRAFT_2844" /note="putative metal binding site; other site" /db_xref="CDD:163641" gene complement(8609..9622) /locus_tag="ClothDRAFT_2845" CDS complement(8609..9622) /locus_tag="ClothDRAFT_2845" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430984.1" /db_xref="GI:256006048" /translation="MFDEVRDVTALLNSNVLLIAGTIIALVVIVLIALIVRKKLFIKL VSFLNKHIDALLFLIGIGKKKADKQKLNQSFAIAGYAYDEKQDIFYSTKDAWQRKFGY CRLYDEAAAPLGMIVDCEPIHFEYKGKRWLIQFWKGQYDLPTGAEVGVYATDKPDINI PGLFKGTFYNSIKDDEFLWMSFTLKKNGKVLFERGDRHWWLTGFKLGEFSQPWELTME ITITLKDAVMCSAFIDGLKRAGYTNKEIKRYGNSVRVIFDKPRTPQPFTRTKVTDEII QKKNKLLCDLYNEVTKGCVTLEEKIAAIREKAPELYQHILGLGRPKELYSSYKRIQRH LTE" gene 9800..11209 /locus_tag="ClothDRAFT_2846" CDS 9800..11209 /locus_tag="ClothDRAFT_2846" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430985.1" /db_xref="GI:256006049" /translation="MFVFLLIASFLTGFCLLKKLTQIKSPIMIISGSFLIGSVFSGTL LYWLDILFVKTLSNYYLSNIAYLVISFAFIAYVYRTNSKIFKELLDTIKEFCRDRVAI ICFIAFVLFSTWFNYDTFSLSNGSITMSGGAWSDLTLHNGFVRSISIGQNIPVEHIFY ANTPAKYHFLFDYYVGKITQTGLHSVHALNLMCILSLSFLLLMIFQFGRTVFKNDAVG ILGALFLLFHSSISGLKWVAENWGWDIFKKMYEKTGWLASTMFEGWGLFNLNVFVNQR HFAFSLAFLVFIVTYVISMYENEKETKNPEPGSGEIIPLNLRNDYSWLLSSCLIGIAV GIMPYWNSVVNTALLSFLGLYTIINIRKKDVFIPMFISTAIAGLVSLPQLLRFKSGAS SLTEYPKFHIGYEVGRFDILDLTEFYFKVLGLKLIIIVIAFLIVPNRKKYCSLSFQCR LYWPIYCSLAWCCMTITNS" gene 11206..11754 /locus_tag="ClothDRAFT_2847" CDS 11206..11754 /locus_tag="ClothDRAFT_2847" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430986.1" /db_xref="GI:256006050" /translation="MISSLIFINCLAAYYLVELFRQKHVILKFISVILCLCLMIAGVL DLMSVKNLPKVNVADKSDFTQWIIENTEPGSTFLTLPTIQYNDNAVSNILMAGGKMYV HNAADSAYKLAERFNILNTILRGEESFEKIKSIIEQEGIDYIVVSPELRQSQEYPVNE EFLKQNFVTKYDFNGITVYSIY" ORIGIN 1 gccttcattc atttgttcca taaactctaa aatgaatgaa ggctgttttc ctgctccttt 61 tactttatct ttattcatat ccttcattta acattctgct ttccggatct tcttaaaaca 121 tcatttctaa gcaaagtgaa aagaactgtt gcaatcggta ccccagtcaa aacaccaatc 181 gggcccccga ctccggcacc gacaattgcc gccaaaacaa cccatattcc gggaagtcca 241 agactgcttc cgacaaccct tgggtatatt aaattatttt ccaactgttg caatactacc 301 aggtaaacta aaaaccatat agctttagtg ggcgaaatca ttaaaaggag catgaacgca 361 caaaatccgc ctatgtacgc tccaaaatac ggcaccaatg cggtaactgc aattaaaacg 421 cttatgagaa gtgcatattc aaaccgaaaa ataaccatcc caataaagca aagcgaacct 481 aaaatgaaag cctccgccag ctgtccatat atatatttgt taaacacatc caccacaaca 541 cgatacacat aagctccctt cttgtacagg cactcgggaa gataagtgct gaaaactttt 601 ttgcattgtc cgataagtct ttcttttccc gccaaaatat atatcgagaa caccaccgtt 661 attaccaatg ttgcaaagaa tgacaaaacc cccgtcgtaa tgctgataat tttcggcatc 721 agctcggtca agctgcttcc caatctgttt gtgtactcaa gaatcaattt gtccaaagac 781 gacaggtcaa tcctttcaag tcccaagagt tcggaaagct cattggtcaa atccctgaaa 841 ttatctatat atgctcccat attgcttaaa aacacttgta tactttttat aagttccggt 901 attataaaac ttattatcag cgtaatcaac aaaagtacca ctaaatatgt aacagtaatt 961 gctattcctc tgacaagtac ttttaatcga tttttgaaca accttttatt caaaaaacct 1021 ctcaaccgcc atgcatggcc tgtttaggac aaaagcaacg gcaattccca taaaaaacgg 1081 tttgaataaa acaataaact tccatacagc gcgcataatc ggtacaaaat ttatgacaat 1141 aagaaccaaa gccactgcat aagtaataac aattatgaga tttcttgtca ttttatcact 1201 caataaaatc aactcctcaa gaaataaagc cggttatcat atacattatt cttatttatt 1261 atattatgaa caactccgga aggacaataa ggataatata tacttttgca attttcaaaa 1321 tttattgtag taaatgtgga gaaaataatc aataacatat aaatcaataa aaccttaaaa 1381 attgtctgca tcacggatat tataaatatt atgattttat tgtattatgt cgtaaaatat 1441 gttagtataa gcactgggtg attatatgtt atgtccgtaa aatagtaata aacattgacg 1501 cgtttttgat gttgtttgta taaggagtga aaatatggaa gaaaatctgg agggtaaaat 1561 tgagaaaaat tcggaagcca atttagagac tcctgttgaa attgaaagta ctgcggaaac 1621 tccaggggaa attcattctc aaaacaaccc ggaaaacaac agcgtaagta cttttacgaa 1681 agttcacacc actgtttcat ttattgtaat ggttttgata aactttctgg ccaataccat 1741 tcctcttaat aaaatgacaa ccggagaaat atccgattta tatcccaatc ttttcgcacc 1801 cgcaggtatg acgttttcca tatggagaat tatctatctt ttgcttggag catatacaat 1861 ttatcaattc ggcattttca agaaaaaaga cggagtattc agcaaaaatt taatcgagca 1921 cctgggaata ttcttttcaa tttcatccat cgcaaacacg gcatggatat ttgcatggca 1981 ttaccacgca attggcatgt ctcttgtatt aaccgctgtt attctggcat gtttgattta 2041 tattaatata aaaatcagaa aagctaatct tgagactctg gaaaaacttt tcataaaact 2101 tcctttcagt atttacttcg gttggattac aataactgca atcgccaata ccattgcatt 2161 cctttcaagc ataggatgga ataggttcgg tatttccgaa ccgctgtgga caagcttagt 2221 tttgattttt actcttttga tttgcggtat tataacattc aaaaaccagg attttatcta 2281 cggacttccc gtaatatggg cttttatcgg tattttaata agacatactt ctgaaaatgg 2341 ctttgaaggc aaatatcccg ggattatcat tcttcttatt gtaatcatta tccttctgct 2401 cattacagat gtttatatat tagtgtcaga caaagaaaag ctaaaaagtt ttaagctgtt 2461 taagcgacta aaatgacggg aaatagaaaa aaataatcgc agtattataa ttttttacag 2521 cctcttatga tataatagcg aaggaaaaat ataatagcga aggaaaaaaa tttaaataaa 2581 ctgcggacgt tatttttaaa tttatcataa ttttaaagcc ataataataa aaaacagaag 2641 ggaggtttat tttaaaaaag cagttgtaag gttgcttccg gtatttagtc aggtgcttaa 2701 tcaaaaagca aattttattt tcgtttcagc ttttcatgtt atgttcatca aatgaaaagc 2761 cgaaataaga tttaagtttt atgtaattgc tgttttgatg taaaagaatc taagttcacc 2821 aaggaggtct gtaaatgatt cagattacta cccaaacaat tcagattgtt gcgatattga 2881 tatcgcttct ttctcttggt gttgctgcat ggctgtactc atgggtgaaa tcccagcctt 2941 catccaatgc ccgtattgct gaaatcggag gatatatccg ccagggagca aatacctttt 3001 taagacgtga atatcttatt ctcgcccgtt ttactgctat agcggctgta ctgattctca 3061 ttttccttcc tcatcctatc tggtcaggta atattactca aaatatctgg atggctgtat 3121 catatatttt tggtacggtt ctttcagcac tggcgggaaa aataggtatt cagattgcaa 3181 ctattgccaa cattaagtct gccgaagcag cacaaaaagg tgttaaaccg gcctttatga 3241 caggattccg cggaggcgct gtaatgggta tggccgttgt aggtaccagc ctcttgggag 3301 ttacccttgt tctattgata gtcggagatg ccagcgcagt ccttggtttc agttttggtg 3361 caagttcact ggctctcttc gcaaaagccg gaggcggtat atttacaaaa actgctgaca 3421 tcagcgccga cctggtaggt aaggtggagc tcggtcttga agaagacgat ccgagaaatc 3481 ccgcagttat agccgacaac gtcggagaca acgtaggtga tgttgccgga atgggcgcag 3541 acctcttcga ctccaacgtt gcctcaatgg ccgctgcact ggttatggcc actgctctcg 3601 gaggacctga cagcaaaaac gtagcaatgg ttttcgccta tgcggcaata ggtcttttgt 3661 cttcggttat tggagtggct acggcacgca tcggcaaaaa cggtgacccg ggaaaagctc 3721 tcaacagttc cacttatgtg accaccgcca tttttgccgt acttacggct ttgtcaacct 3781 acatctttaa cttcgaatgg cgtatttggg gcgcaactgc cataggtctg atagtcggaa 3841 ccattatagg tcttacctct gactatttca caaacgacgc aaaacctccg gttcgagccg 3901 ttgcaaatgc ttcaaagtca ggacctgctt ttaccatact ttcaggtttt tcctacggat 3961 tgctaagtgc ccttccttca ctgattggta tagcagtaac tgctttaata tcctattata 4021 tttgtgaacc tctcggaagc ggctatggaa tgttcggtat ttcaatgtca gctctcggta 4081 tgctttcaat agtcggaatg attatttcca acgacgctta cggtccgatt gttgataatg 4141 cccgcggtct ggctgaaatg ggcggctttg gtgaaaaggt tattgccatt gccgacgaac 4201 tggattcagc cggaaacact gtcaaggcgg taacaaaagg attctccata agtgccgcag 4261 gtcttacggt tatatccctt ttgggtgctt tcatgagtga ggtaaacact gctgcatccg 4321 aattgggtgt tcagggaatt gcgaacttcg atatcatgaa tccaactgta ttcttcggac 4381 ttatagttgg tgtggcaatc ccggcagtat tctctgcaat gttgatgctg ggtgttgaca 4441 aaaacgctca gagaatggtt gctgagattc atcgtcaatg ggatacaatt ccggggctta 4501 aagaaggaaa ggaaaatgcc aaaccggatt acgacaagtg tatagatatc gctacaacag 4561 gctctcttaa ggaattgatc cctgccggat tagttgcaat attctcgacc atacttgtcg 4621 gctttatcgg cggtgcatcg gcaatcggag gatttttgac cggtaacatt acttccggac 4681 tcctgcttgc acttctgatg tccaatgcag gcggtctttg ggacaactcc aaaaagtatg 4741 ttgaggcagg aaattgcggc ggaaaaggtt caacagcaca caaagctgcc gttgtgggag 4801 ataccgtagg tgacccgttc aaagatactg ccggtccttc catcaatacg cagattaccg 4861 ttgtgtcact ggtttcttcg ctgcttgcat cattgttcct taatgtactc aattttctaa 4921 aaaagcgaaa cggatttgct ttaataagtg ttgcgtaaaa agccttcctt tcacggaagg 4981 ctttttgcgt tttttgcttc taagactaaa acaaaacgtt caatatttct tacactaccg 5041 gcgtataatt tcgactcaaa ctgttcgaat atatccttat atttgcataa aatatgaaac 5101 agtcacatca gcctaaactg cgtgccctca gtgtttcact atttttactt cattttttca 5161 atctgttttt caatcaaaaa cactatagat attttttcaa tttagtatta taatgttcta 5221 atgtttgata agaatatcac attcaaacta acttgaaaat gtttttattg aggagttttt 5281 attcatgaac aaaagtcaaa caaaaataaa tgattttgtc tatggattta aaaaaggaac 5341 accgattcta ttaggataca taccggtagc ttttactttc ggccttatgg ctgtcggcgg 5401 cggacttcat ccgttaatgg cagtgtttat ttccctgacc aaccttacca gcgcagggca 5461 gtttgccggt acaaatttaa ttatccaggg tgcgggttat cttgaaattg cccttaccac 5521 cttcgttata aatatcaggt acatgctgat gtctctttct ctgtctcaaa aaatcgatcc 5581 aaagattaca ctttggcagc gtcttgtctt cggatttgga ataaccgacg aaaccttttc 5641 ggtggcttca atggaaaaag gaaggttgtc ttatttctat atgttggggc taatcgcagg 5701 accaattttc ggctggagtt tcggaacggc tttaggtgcc ttcaccagtt ccgcattgcc 5761 cgaatccctg agcaatgcaa tgggtattgc cttgttcgcc atgtttattg caataatagt 5821 tccgcctgca aaaaaatcca gaccggttct gatgattgta cttatttcag ttgcgataaa 5881 tctggcttta aaatatatcc ctctctttag ctttatttca agcggttttg ctattattat 5941 ttccaccgta cttggtgccg gaatcggtgc cgccatatgg cccataaaag aagaaaatcc 6001 cgttttaaag gaggagtaaa atcatgccgt atgcactcat tgccgctttg ttaatggcgc 6061 ttgttacata tttgcccagg gtacttccca ttgccgtctt tagaaaagaa atcaaatcaa 6121 cttatataaa atctttttta cggtatgtcc cttatgcagt attgggagca cttacgtttc 6181 cggacatttt tagttccacc aacaattacg gcactgccat ctgcggcact gttgtcgctt 6241 taattctggc ttatatggaa aaaagccttt ttatagtggc attgggagca atattgaccg 6301 tatatgtcac cggattgttt ctatagtaat cccgctgtac ttcttaaaat cctcaatcat 6361 ctccgcggtt aattcttttc ttctgcatat ttgctcataa agccggacgc tttttctcgg 6421 tatcctctcc tgcgtgcgga aattgcagtc gtaaaggccg aaatccgttg actcaccttc 6481 aagccattcg aagttatcca tcagcgtcca gtaataatac cgttctatcg gaatcccttc 6541 ttttatggct tttgcaatat aagcaagatg gctggcaata aagctcggcc gtttggtgtc 6601 atttttatcg cttattccgt tttcggttat ataaatggga agtttatatt tcttatagta 6661 cctcttgcat actttgtata tgccttccgg atatatgtcc cacccgaggt ccgatttggt 6721 caaatccttg tcacatacaa gctcgtgaaa ataaagggac gggtcaaata cgaactcaac 6781 aatatttctt gtataataat taattcccaa aaaatccgca tacctgcctt ttttatggct 6841 tgaacccttt ttggaaagag gaaacatcat gtgccctgtc gtcatgcctt ccataaacat 6901 ttcgttaaac agataatcta caactttggc tatcattttt ccggtagaac ttatcccgtc 6961 aaagatgcga aggtgcattg ccgttcctac cattgtcctg cctgcaaatt tgcgctctct 7021 tcttatccta tgtatcagcc ggtatagttt tacatgggtg tttataagct ctgccgtaac 7081 ctttaaccct tcagacaggc ttctttcccc cggagggaaa atgccgatta cataaccaaa 7141 atcaacatag acattgggct cgttaaaggt tacccagtcg cttacaaggt cacccaaatt 7201 ttcaaccaca tacttcacat attctataaa aatatctgca ttgcccgttt ttttccatcc 7261 ccccatttca tgaaaccaaa tgggctcgga aaagtgatga agcgtaacca gaggctttat 7321 gttgttctcc accaaaagct taatctcatc tctgtaatgt ttcattgcgt catcggaaaa 7381 tttgcccctg gaaggctcta ttctgctcca ctcaagactc attctgtggg tttgaactcc 7441 caagttcttc aacagctccg tatcctcctc caccctgttc caatggtcac atgcagtgat 7501 acagctgctg gagtccttga tacgtccttc ctggcaccac ttataccatg tatttcccgt 7561 atccccaccc tcaatctgag tacttgcggt agcggttcca aacatgaatt catcattaag 7621 cttaaaagta accattatcg ccaccccctt tacacgttta tatgtttatc tgaagtattc 7681 tttaagcttc accggcttct ctatttcatc cctgccgacg tacaaggtac cgtcatcctt 7741 ggtttttaca ctccatttga caagtgctat ctttccatgt acaatctcta ttcccgttat 7801 gccataagga tggacacagc agccgtcatt aaaatatggt ggctggccga ccgccggaaa 7861 taccgctctg tgagtgtggc ctgcaataat catctgattg ttgctcttga cccagtctac 7921 aatcttgttt gcaataactg tttttttccg gtcatttttc gatgcactgt ttgggtcccg 7981 aattcccaac aactcaagcg gtctccataa ataccttaca aaaaatttgc tgaccctcca 8041 caatttgtcg tttgcaaaat ccgcctgatg tccgtgtaca agaaatattt tgtctcccgt 8101 gaccctgtgc cgtaaaatca aaccctcgtg tacttttgtt ttaaaaaatg cggctacatt 8161 tcttttgtcg ccgtcttcca aatacttaaa actttttctt tccctaaggg ttctcaatgc 8221 atactttttc ttctcaatat catgattgcc gtagataaag taagccctgc cttcatcaat 8281 aaacctggtc agcaaggaaa agacgtctct gtgttcactt attatgtcac atatattgtc 8341 attttcccac agctcgtctc catcccccag ttctatataa gtaaaattat tgcgatagta 8401 ataggtcagt gcagcatagt aaatgttctt gtttttactg aaattatccg cccagcttcc 8461 gtctcccctg tgacaatcgc tcattatgat aattttggaa aaatcatcaa aaggaatctc 8521 ctccgcagac tcaaaaactt ccgacaacct cttgaattca tacatttcaa acacccccac 8581 aaataccgca aaacctattc cggcatgctt attccgtcaa atgcctttga atccttttat 8641 aggagctgta caactctttt ggtcttccca aaccaagaat gtgctgatac aattccggcg 8701 ctttttcacg gattgcagct atcttttctt ccaaagtaac gcatcctttt gtaacttcat 8761 tatataggtc acataaaagt ttgttttttt tctggatgat ttcatcagtt acctttgttc 8821 gtgtaaaagg ctggggagta cgaggcttgt caaatattac ccttacggaa tttccgtatc 8881 tttttatctc cttgtttgta tatcccgctc tcttcaatcc gtcaataaat gccgaacaca 8941 tcacagcatc ttttaatgtt atggtaatct ccatggtcaa ttcccacggc tgggagaatt 9001 caccaagttt gaaacctgtc aaccaccaat gccggtctcc gcgctcaaaa agtacttttc 9061 cattcttttt taaagtaaat gacatccata aaaactcatc atcctttata ctgttataaa 9121 aagttccttt aaataacccc ggaatgttta tatccggttt gtcggttgca tataccccca 9181 cctcagcacc ggtaggcaaa tcatattgcc ctttccagaa ctgaattaac catctctttc 9241 ccttgtactc aaaatgaatc ggctcacaat ccactatcat tcctaaaggt gccgccgcct 9301 catcatacaa acggcaatat ccaaattttc tttgccatgc gtcttttgtg gaataaaaaa 9361 tgtcctgctt ttcgtcatac gcataaccgg caatggcaaa ggattggttg agtttttgct 9421 tgtctgcctt ttttttgcct attcctatga gaaacaaaag cgcgtcaata tgtttattca 9481 aaaacgaaac aagttttatg aaaagttttt ttctgacaat cagggcaatt aaaacgatta 9541 caactaaagc aattatagtt ccggcgataa gcaatacgtt tgaatttaac aaagccgtta 9601 cgtctctcac ctcgtcaaac ataagaatcc caccccaaac ataatttctt tgtaacataa 9661 tattctgaat cgaatgatta tgttaataga attgaaatta atataatttg acaaaaaact 9721 attattttct tatttattgt gatataattt tttttgtatt tgcgcagata gaaatttatt 9781 tgtcgggaag tgggatgata tgtttgtttt tctcttgatt gcatcattct taacgggatt 9841 ttgcctgctt aaaaaattaa ctcaaataaa atccccgata atgattattt ctggttcttt 9901 tctaataggg tccgtttttt ccggcacact gctatactgg cttgatatac ttttcgttaa 9961 aaccctgagc aactactatc tcagcaatat agcatacctc gtaatatctt ttgcttttat 10021 agcatacgta taccgaacaa acagcaaaat attcaaagag cttcttgaca cgataaaaga 10081 gttctgccgt gacagagttg caataatttg ctttatcgct tttgttttat tttcaacgtg 10141 gttcaattat gataccttca gtttgtcaaa cggaagcatc accatgtccg ggggagcatg 10201 gagcgattta actcttcaca acggatttgt acgttccata agcattggcc aaaacattcc 10261 ggttgagcat atcttttacg ccaatactcc ggcaaaatat cactttctgt ttgactacta 10321 tgtgggtaaa ataacccaaa ccggcctgca ttcggttcac gccttgaatc ttatgtgtat 10381 tttgagtctt tctttcctgc tgttaatgat atttcagttt ggaagaacag tatttaaaaa 10441 tgatgccgtg ggaattctcg gcgccctctt tttattgttc cacagctcaa taagcggttt 10501 aaagtgggtt gccgaaaact ggggctggga tatattcaag aaaatgtatg aaaaaaccgg 10561 ctggctggct tcaaccatgt ttgaaggctg ggggcttttt aacctgaatg ttttcgtaaa 10621 tcagcggcac tttgccttct ccttggcatt tcttgttttc atcgttacat atgtgatttc 10681 tatgtatgaa aatgaaaaag agacaaaaaa tccggaaccg ggaagcggtg aaataatccc 10741 attgaacctg cgtaacgatt attcatggct tttatcaagc tgtcttatag gaattgctgt 10801 aggtatcatg ccttactgga actctgttgt aaacacggct ctgctttcat ttttgggact 10861 gtatacaatt ataaatataa gaaaaaaaga tgtctttatt ccaatgttta tctcaaccgc 10921 catagccgga cttgtttcac tgccgcagct tctgagattt aaatcaggtg cttcgagcct 10981 gacagaatat ccaaagtttc atatcggcta tgaagtggga cgctttgaca tattggattt 11041 aacagaattt tacttcaaag tcctgggatt aaaattaatt ataattgtta tagcattttt 11101 gattgtaccc aacagaaaaa aatactgttc cttatccttt cagtgccgtt tgtactggcc 11161 aatttactgc agcttggcgt ggtgctgtat gacaataaca aactcatgat ttcatcactc 11221 atatttataa actgcctggc agcttactac ttagtagaac ttttccgcca aaaacatgta 11281 atacttaaat tcatatccgt tatcctttgt ctctgcctta tgattgccgg agtgcttgac 11341 ttaatgtcag tcaagaatct tcccaaagtc aatgtggcag acaaatcaga cttcacacag 11401 tggattattg aaaacaccga accgggctca actttcctta ctctgccgac catacaatat 11461 aatgacaacg cagtatccaa catactgatg gcaggcggta aaatgtatgt acataatgca 11521 gccgactcgg catacaagct cgccgaacgc ttcaacattc taaacaccat attaaggggc 11581 gaagaaagtt ttgaaaaaat aaaaagcatt attgagcagg aaggtattga ctatatcgtg 11641 gtcagtccgg aactcagaca aagccaggaa tacccggtaa acgaggaatt tctcaaacaa 11701 aactttgtaa caaaatatga ttttaacggc attaccgttt actcaattta ttagtgttgt 11761 gcagttgttt ttgaagcatc aacagacggg cagaatatcg aaccggttaa ggatgacatg 11821 aagtatgagg aaaaaataac caaagataca gaagaaataa aaaatatgac ccatgtgaag 11881 atgccgttaa catacagatc atgtttttaa aggacggcat ttattacaat gtctttggag 11941 aacatgttga aattgacgac ttgccggatg ttattgattc tttggaataa ctaaagataa 12001 at //