#!/usr/bin/env python # Copyright (c) 2005 Clare Gollnick # # This software is distributed under the MIT Open Source License. # # # Permission is hereby granted, free of charge, to any person obtaining a # copy of this software and associated documentation files (the "Software"), # to deal in the Software without restriction, including without limitation # the rights to use, copy, modify, merge, publish, distribute, sublicense, # and/or sell copies of the Software, and to permit persons to whom the # Software is furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included # in all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE # AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, # OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN # THE SOFTWARE. # """Read sequence information in MSF format. This is a file format for biological sequence data. The sequences are interweaved and each line is labeled with the sequence name. The MSF format can be identified in one or more of the following ways: 1. The word PileUp on the first line (optional) 2. the word !!AA_MULTIPLE_ALIGNMENT or !!NA_MULTIPLE_ALIGNMENT at the start of the file (optional) 3. the word MSF on the first line of the file, and the characters ".." at the end of this line (optional) 4. A header containing sequence information followed by a line with the characters "//" """ from __future__ import absolute_import import re from ..seq import * from ..utils import * from . import * example= """ PileUp MSF: 64 Type: P Check: 767 .. Name: Cow Len: 100 Check: 3761 Weight: 1.00 Name: Carp Len: 100 Check: 1550 Weight: 1.00 Name: Chicken Len: 100 Check: 2397 Weight: 1.00 Name: Human Len: 100 Check: 9021 Weight: 1.00 Name: Loach Len: 100 Check: 984 Weight: 1.00 Name: Mouse Len: 100 Check: 2993 Weight: 1.00 // Cow MAYPMQLGFQ DATSPIMEEL LHFHDHTLMI VFLISSLVLY IISLMLTTKL Carp MAHPTQLGFK DAAMPVMEEL LHFHDHALMI VLLISTLVLY IITAMVSTKL Chicken MANHSQLGFQ DASSPIMEEL VEFHDHALMV ALAICSLVLY LLTLMLMEKL Human MAHAAQVGLQ DATSPIMEEL ITFHDHALMI IFLICFLVLY ALFLTLTTKL Loach MAHPTQLGFQ DAASPVMEEL LHFHDHALMI VFLISALVLY VIITTVSTKL Mouse MAYPFQLGLQ DATSPIMEEL MNFHDHTLMI VFLISSLVLY IISLMLTTKL Cow THTSTMDAQE VETIWTILPA IILILIALPS LRILYMMDEI NNPSLTVKTM Carp TNKYILDSQE IEIVWTILPA VILVLIALPS LRILYLMDEI NDPHLTIKAM Chicken S.SNTVDAQE VELIWTILPA IVLVLLALPS LQILYMMDEI DEPDLTLKAI Human TNTNISDAQE METVWTILPA IILVLIALPS LRILYMTDEV NDPSLTIKSI Loach TNMYILDSQE IEIVWTVLPA LILILIALPS LRILYLMDEI NDPHLTIKAM Mouse THTSTMDAQE VETIWTILPA VILIMIALPS LRILYMMDEI NNPVLTVKTM """ names = ('msf', 'gcg-msf', 'gcg', 'PileUp') extensions = ('msf') end_header=re.compile(r'(//)(\s*)$') seq_line=re.compile(r'\s*(\S+)\s+([\S\s.?]+)$') def iterseq(fin, alphabet=None): """Iterate over the sequences in the file.""" # Default implementation return iter(read(fin, alphabet) ) def read(fin, alphabet=None): alphabet =Alphabet(alphabet) seq_ids=[] seqs=[] block_count=0 for token in _line_is(fin): if token.typeof=="begin_block": block_count=0 elif token.typeof == "seq_id": if len(seqs)<= block_count: seq_ids.append(token.data) seqs.append([]) elif token.typeof=="seq": if not alphabet.alphabetic(token.data): raise ValueError( "Character on line: %d not in alphabet: %s : %s" % ( token.lineno, alphabet, token.data) ) seqs[block_count].append(token.data) block_count +=1 if seq_ids==[]: raise ValueError("Parse error, possible wrong format") seqs = [ Seq("".join(s), alphabet, name= i) for s,i in zip(seqs,seq_ids)] return SeqList(seqs) def _line_is(fin): header, body, block = range(3) yield Token("begin") state=header for L, line in enumerate(fin): if state==header: if line.isspace():continue m=end_header.match(line) if m is not None: yield Token("end_header") state=body continue else: continue if state==body: if line.isspace():continue yield Token("begin_block") state=block #skips to a block of sequences if state==block: if line.isspace(): yield Token("end_block") state=body continue m=seq_line.match(line) if m is None: raise ValueError("Parse error on line: %d" % L) if m.group(1).isdigit() and m.group(2).strip().isdigit(): continue yield Token("seq_id",m.group(1).strip() ) data=m.group(2) data="".join((data.split())) yield Token("seq",data.strip() )