ID   CHS3_BROFI     STANDARD;      PRT;   394 AA.
AC   O23729;
DT   15-JUL-1999 (Rel. 38, Created)
DT   15-JUL-1999 (Rel. 38, Last sequence update)
DT   15-JUL-1999 (Rel. 38, Last annotation update)
DE   CHALCONE SYNTHASE 3 (EC 2.3.1.74) (NARINGENIN-CHALCONE SYNTHASE 3).
GN   CHS3.
OS   Bromheadia finlaysoniana (Orchid).
OC   Eukaryota; Viridiplantae; Embryophyta; Tracheophyta; Spermatophyta;
OC   Magnoliophyta; Liliopsida; Asparagales; Orchidaceae; Bromheadia.
OX   NCBI_TaxID=41205;
RN   [1]
RP   SEQUENCE FROM N.A.
RC   TISSUE=Flower;
RA   Liew C.F., Lim S.H., Loh C.S., Goh C.J.;
RT   "Molecular cloning and sequence analysis of chalcone synthase cDNAs of
RT   Bromheadia finlaysoniana.";
RL   Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: THE PRIMARY PRODUCT OF THIS ENZYME IS 4,2',4',6'-
CC       TETRAHYDROXYCHALCONE (ALSO TERMED NARINGENIN-CHALCONE OR CHALCONE)
CC       WHICH CAN UNDER SPECIFIC CONDITIONS SPONTANEOUSLY ISOMERIZE INTO
CC       NARINGENIN.
CC   -!- CATALYTIC ACTIVITY: 3 MALONYL-COA + 4-COUMAROYL-COA = 4 COA +
CC       NARINGENIN-CHALCONE + 3 CO(2).
CC   -!- PATHWAY: PART OF THE BIOSYNTHETIC PATHWAY FOR ALL CLASSES OF
CC       FLAVONOIDS, A LARGE CLASS OF SECONDARY PLANT METABOLITES, MANY
CC       OF WHICH ARE BRIGHTLY COLORED.
CC   -!- SIMILARITY: BELONGS TO THE CHALCONE/STILBENE SYNTHASES FAMILY.
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DR   EMBL; AF007097; AAB62874.1; -.
DR   InterPro; IPR001099; -.
DR   Pfam; PF00195; Chal_stil_synt; 1.
DR   PROSITE; PS00441; CHALCONE_SYNTH; 1.
KW   Flavonoid biosynthesis; Transferase; Acyltransferase;
KW   Multigene family.
FT   ACT_SITE    165    165       BY SIMILARITY.
SQ   SEQUENCE   394 AA;  42941 MW;  2F8D14AF4870BBB2 CRC64;
     MAPAMEEIRQ AQRAEGPAAV LAIGTSTPPN ALYQADYPDY YFRITKSEHL TELKEKFKRM
     CDKSMIKKRY MYLTEEILKE NPNICAFMAP SLDARQDIVV TEVPKLAKEA AVRAIKEWGH
     PKSRITHLIF CTTSGIDMPG ADYQLTRLLG LRPSVNRFML YQQGCFAGGT VLRLAKDLAE
     NNAGARVLVV CSEITAVTFR GPSESHLDSL VGQALFGDGA AAIIVGSDPD SATERPLFQL
     VSASQTILPE SEGAIDGHLR EIGLTFHLLK DVPGLISKNI QKCLLDAFKP LGVHDWNSIF
     WIAHPGGPAI LDQVEIKLGL KAEKLAASRN VLAEYGNMSS ACVLFILDEM RRRSAEAGQA
     TTGEGLEWGV LFGFGPGLTV ETIVLRSVPI AGAE
//