LOCUS NZ_ACVX01000013 78039 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00015, whole genome shotgun sequence. ACCESSION NZ_ACVX01000013 NZ_ACVX00000000 VERSION NZ_ACVX01000013.1 GI:256004413 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 78039) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 78039) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000013. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..78039 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene <1..195 /locus_tag="ClothDRAFT_1255" CDS <1..195 /locus_tag="ClothDRAFT_1255" /inference="similar to AA sequence:KEGG:Noc_0056" /note="KEGG: noc:Noc_0056 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429394.1" /db_xref="GI:256004414" /translation="ISFDFPDEKDIISNKDVFVNMMDLFSSKYPDKGYLIVVDEFLDY LGGRKDQEIIFDLNFMREIG" gene 445..3273 /locus_tag="ClothDRAFT_1256" CDS 445..3273 /locus_tag="ClothDRAFT_1256" /inference="similar to AA sequence:KEGG:Plav_3555" /note="KEGG: pla:Plav_3555 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429395.1" /db_xref="GI:256004415" /translation="MEEYVNLFPIHPSYIEVFNKIYIIENRHILKNISEIIKRILDNE ITEDSPGIVSFDSYWTFIKDNFSYRTDANIKEVVEKSGMLEDIINRSFPKRLYKPLAL QIIYALSVHRLTTGDISIRAGLTAENLRDDLCLYLKGMPDQSSDTLQSLIQTVLKDIM TTVSGQFIEYNADNGQYYLDLKKDIDYDEKITQRAAFMDDDSLNNYFYDVVYYCLEWD QKEYVDNFKIYEHRLNWMSHNIFRSGYLFFGTPESRPTAQPPEDYYIYFIPPYGNESY TDNKKEDEVFFLFKPNEEFKNTLKLYGAAQILKGLAEVKNKPAYQSKAEVYKKELTKY LSENKNTCFEVVYKGEKKQLLEVMGKLYKSTNPFKETIDLVASICLDEYFAKKYPEMP KFKIQITSRNRVEIIRAGIDRFAGRKSQQANALLESFGLLDGDKITVQNSKYAQYFIK ELEKIPANEVINFSDIYTEVPNKDEYYIDKQFGISYALLPIVLLALVHTGHAVITLRN GTTLTASDLEILPKIQATDIYEFKYISKPKDMRLVELVKLYELLELPAGLINNPAQRE AGLGRLLAKAQETANIAVRANSKLNGDFELWGEPLIAEHIASDYKAAAKRVLDMLGNF QSRFNTVAKLNNFNYTMEQIEQLGKDITASKTVLEYEKFRNECLANVSYMMNLERMEL GNTLRAAIETAKESFRKIRDNIPEDMSGEAAAADVNELLTKVKNQYIDIYFSEHQKRR LGVSDGRRKGELVSSVKLANLKRLREINSIFSAHKLDNIEKELAGLKVCYELTPEMLK TSHFCPKCHFLMNEEDIPVKGRLDEIEERIDNLLDEWTNTLYNTVTDPTLIEQKQYLS PQQCQVIDEFINTKRLPEKADQFFITAIKDLLQGFEPVAIAADELIDRLSALGPCDID TFQHKLKELVDDYIKGKDKEKLRIIIKR" misc_feature <448..>783 /locus_tag="ClothDRAFT_1256" /note="Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1483" /db_xref="CDD:31672" gene 3286..5841 /locus_tag="ClothDRAFT_1257" CDS 3286..5841 /locus_tag="ClothDRAFT_1257" /inference="similar to AA sequence:KEGG:Noc_0059" /note="KEGG: noc:Noc_0059 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429396.1" /db_xref="GI:256004416" /db_xref="InterPro:IPR002052" /translation="MKKLTKEDIDKVRHIEGFPIANDEDIIALSNPPYYTACPNPFIE DFIKEHGKPYDEATDDYHREPFAADVSEGKNDPIYNAHSYHTKVPHKAIMRYILHYTE PGDIVFDGFCGTGMTGVAAQMCGNPDPELKARIEAEMPYVKWGARKAILNDLSPAATF IAYNYNTPVDVAEFEKEAKRILEECEKEYGWMYETQHTINGEIQYGIDGKPIMGRINY TVWSDVFICPTCSNEIVFWDAAVDKEKGKVNDTFYCPHCNSQLTKRSCERAQETHFDA RLNEFVTMAKQVPVLINYSVGKKRFEKTPDEYDLALIEKIDNMDIPYWYPTDRMCEGS ESRRNDRYGITHVHQFYTKRNLYLNAWLRNKIIKVKDKCISDILLFGFNNVQQRHCKL NAMRFNVSFPSNITSGTLYLPSMIRENNIIDQLSNKYFKRIVKAFKDNTSKYSIVSTN STTSNIINSNNSIDYIFTDLPFGSNLNYSELNFLWEAWLKVFTNQEPEAIINAVQGKG LLEYQSLMTRCFEECYRVLKPGRWMTVVFHNSQNSVWNAIQESLMRAGFVIADVRTLD KQQGSFKQVTTTSAVKQDLVISAYKPKESFKREFISHAGSEETAWSFIQQHLEKLPVV VVKNGKIELIEERKAYLLYDRMVAYHIMNGIPVPLDATDFYKGLDERFLKRDGMYFLP DQVNEYDTARIVNDVEPIQMELLVTNEKSAIAWLYKQLETPQTYAELQPKFMQEIRAW DKFEKRPELSELLEENFLQNEEGKWYIPDVTKASDVAKLREKKLLKEFEGYLATKGKL KLFRTEAIRVGFAKLWADKNYKLIVETAERLPESVILEDDKLLMYYDLSLGRI" misc_feature <3406..3648 /locus_tag="ClothDRAFT_1257" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene 5852..8521 /locus_tag="ClothDRAFT_1258" CDS 5852..8521 /locus_tag="ClothDRAFT_1258" /inference="protein motif:PFAM:PF00271" /note="PFAM: helicase domain protein; SNF2-related protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicase; KEGG: dno:DNO_0177 DEAD helicase domain-containing protein VrlO" /codon_start=1 /transl_table=11 /product="helicase domain protein" /protein_id="ZP_05429397.1" /db_xref="GI:256004417" /db_xref="InterPro:IPR000330" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR006935" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014021" /translation="MLQIGDYVFDKTKNERVQILEISEVWGFVSYKVFNTSTGKVYKL SADDICAEIPEKHYNESYLRYVALLSKIKNKISQGILSKLSCGIIPLPHQLHVLNRAL SNNNVRYILADEVGLGKTIEAGLIIKELKARGLIRRILIVCPTGLVTQWDMEMKEKFN EKFHVILPENYDAIRQITGNEDVYGQFDQVISPMDSIKPLERRAGWTEEKIAKYNEER IYSIINSGWDLIAIDEAHRVAGSSGEVARYKLGKLLAAASPYLLLLTATPHNGKTEPF LRLIRMIDEKAFPNADAVVKEQVAPYVIRTEKREAIDHNGNKLFKNRIIKVIEMHWDE RHSMQRKLYEMVSDYVAKNYNKAMRNRGKNMWFVFLLIMMQRMVTSSTSAVRESMERR VRVLEEQAFKYQSMSEEEFAEMELEENMEEAIAAISLGIEEEITQLNDIIAVAKQAEF QYLDVKVEPLFEIIDDLFAEDRQRKIIIFTEFVATQSYLVKLLKDRGYSTSILNGSMS IEERNAVLHEFKTQTDILISTDAGGEGLNLQFSNCIINYDLPWNPMKIEQRIGRVDRI GQQRDVVVYNFILADTVENRVKTVLEEKLSVILREIGIDKYSDILDSETAELNFTDAY MQSIRNPNDIEFNIRRIEEDLKTQVKNTMQIRELIKEEKDLTSMIGAGSTFDFEHALR QMVTYYENYKGNPFLPIENFSINDPIIFEHLNKEIEQDWRMPLLSVSIKDFPNEKGYF MLWKISLISDSREQKVIPIFINCDFILRPMAGKKIWEAILDKDRIITVRKGEEIDTET KNKLYKVSQEFAYDTFLTMKAELEKRNEETYRKYLYALNLRIEAAQRIGIENIRKHKL MTLNREKAEIEANYQAGKKICPDFKPILIAYME" misc_feature 6179..6601 /locus_tag="ClothDRAFT_1258" /note="DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046" /db_xref="CDD:28927" misc_feature 6197..6211 /locus_tag="ClothDRAFT_1258" /note="ATP binding site; other site" /db_xref="CDD:28927" misc_feature 6548..6559 /locus_tag="ClothDRAFT_1258" /note="putative Mg++ binding site; other site" /db_xref="CDD:28927" misc_feature 7187..7576 /locus_tag="ClothDRAFT_1258" /note="Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079" /db_xref="CDD:28960" misc_feature order(7292..7303,7361..7366,7436..7444) /locus_tag="ClothDRAFT_1258" /note="nucleotide binding region; other site" /db_xref="CDD:28960" misc_feature order(7460..7462,7523..7525,7535..7537,7544..7546) /locus_tag="ClothDRAFT_1258" /note="ATP-binding site; other site" /db_xref="CDD:28960" gene 8526..9971 /locus_tag="ClothDRAFT_1259" CDS 8526..9971 /locus_tag="ClothDRAFT_1259" /inference="protein motif:PFAM:PF08665" /note="PFAM: PglZ domain protein; KEGG: noc:Noc_0064 hypothetical protein" /codon_start=1 /transl_table=11 /product="PglZ domain protein" /protein_id="ZP_05429398.1" /db_xref="GI:256004418" /db_xref="InterPro:IPR013973" /translation="MIEKRVAELFSIEYEKRLLIFDTDRFCDAFDYIGFLISRDFEVI RYEDIEAFRLRYELDIRNSEHKYAVVVFSDIYVPYDIRKQFFEVHISFKNIFPKLHED TVQRYVKDIDLISFAYEQLYFSCDTREKTEEFISNTVFSKENVKNYCELMTKKLLPSG DKSGITAKEWIEIARKKALIDYYAARANISVDTSFVDVYFEKFIFNGYQKLSGETKKD APAILPKVIDFIAHGKTALVVVDGMSLFDFEVISRYFEGIEYEYYCTFALIPTTTAIS RQSLLTGKYPRELKHPFTLSDEEKGFIETAQNAGYTKQQILYAKGFNPPVNHFTKFMA VIINDIDDLVHGQKQGRVGMYNDISLWAKSGKLQMLIKDLYAQGFDVYITSDHGNTPC IGAGTIRGVGVEVETKSKRMFVLKDFAELRNFFGDKVVAYPGYYLDNDYKYYVCKSGV SFDNMNEEVMTHGGISIDEVIVPFIKVRTVI" misc_feature 9225..9713 /locus_tag="ClothDRAFT_1259" /note="PglZ domain; Region: PglZ; pfam08665" /db_xref="CDD:149651" gene 9972..10415 /locus_tag="ClothDRAFT_1260" CDS 9972..10415 /locus_tag="ClothDRAFT_1260" /inference="similar to AA sequence:KEGG:Noc_0065" /note="KEGG: noc:Noc_0065 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429399.1" /db_xref="GI:256004419" /translation="MAKMIGLSRSIRLEWLNKTAELVLEGKDYTQIKDELNEYLSFEI KSPTNIRKTREILTNIWVKIPDALSTLKRQALEAYKDDKSNKLALHWSMMLVAYPVFC DVCALIGKLTSIQDTFTHPGLKKSCLKYGGNVLLCSIPSIRYYKP" gene 10412..10675 /locus_tag="ClothDRAFT_1261" CDS 10412..10675 /locus_tag="ClothDRAFT_1261" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429400.1" /db_xref="GI:256004420" /translation="MKQIGAIENEKVGVYRIKKYPVTDVKTIQVLLLAILHLRERAYY EIAELSSVPQVFPFEFNVSYEWLHDSDLFTLSNFGGKVVLTLD" gene complement(11785..11973) /locus_tag="ClothDRAFT_1262" CDS complement(11785..11973) /locus_tag="ClothDRAFT_1262" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429401.1" /db_xref="GI:256004421" /translation="MNYGASKKLFVRKLTAGENNELRKAIKTSTSSKTIRYAKVILAS SEGMNSKRLSEIYHYSQP" gene complement(12340..13476) /locus_tag="ClothDRAFT_1263" CDS complement(12340..13476) /locus_tag="ClothDRAFT_1263" /EC_number="2.7.1.31" /inference="protein motif:TFAM:TIGR00045" /note="KEGG: vsa:VSAL_I2594 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase" /codon_start=1 /transl_table=11 /product="glycerate kinase" /protein_id="ZP_05429402.1" /db_xref="GI:256004422" /db_xref="InterPro:IPR004381" /translation="MKKVVLVPDSFKGTMSSSKVCEIMEKKVKEYFPCCEVISIPVAD GGEGSVDCFLRAVGGEKIRVKVKNPYFEDMEAFYGLIDQGKTAVIEMAACAGLPLVEN RKNPSKTTTYGVGQLIMDAAGRGVKKIIVGLGGSCTNDGGCGAAAAVGIKFINRNGNE FIPTGGTLHEIDSIDMSGKAEILKGIEIVTMCDIDNPMYGPKGATYVFAPQKGADRDM VMHLDRGIYHLSEVIKKDLNKDLADIPGTGAAGAMGAGMMAFFDSTLQMGIETVLDTV RFDSLIHDADMIFTGEGKLDSQSLRGKVVMGVAKRASVANVPVIVVAGGADLDIDEIY NFGVTSVFTINRLPEDFEISRSKSMENLNFTMDNILRMIKNMNG" misc_feature complement(12355..13470) /locus_tag="ClothDRAFT_1263" /note="Glycerate kinase family; Region: Gly_kinase; cl00841" /db_xref="CDD:186217" gene 13922..14335 /locus_tag="ClothDRAFT_1264" CDS 13922..14335 /locus_tag="ClothDRAFT_1264" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429403.1" /db_xref="GI:256004423" /translation="MDSEVLRSEEGDMPNPNFALADGLLLEERKYFCPVNIPLCEIKT VRTEKDIFDENELKYFNYKVEKIISKLQDWNIPPLIAQFDGIDFVLTDGNHRYSALKR LGKTSYYTIVWCSRKFADLARKIMTEKGWFKDKQI" gene 14444..14578 /locus_tag="ClothDRAFT_1265" CDS 14444..14578 /locus_tag="ClothDRAFT_1265" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429404.1" /db_xref="GI:256004424" /translation="MRETGIEQRNEDSFLESKMLDLTAKEYELLELFVDSMSCSEMNP " gene complement(14958..17222) /locus_tag="ClothDRAFT_1266" CDS complement(14958..17222) /locus_tag="ClothDRAFT_1266" /inference="protein motif:PFAM:PF05569" /note="PFAM: peptidase M56 BlaR1; KEGG: spl:Spea_3209 TonB family protein" /codon_start=1 /transl_table=11 /product="peptidase M56 BlaR1" /protein_id="ZP_05429405.1" /db_xref="GI:256004425" /db_xref="InterPro:IPR008756" /translation="MTKLFELFLQNSFTGIIFILVILIIRQLTKNFSKRYVTVLWILL LAELLFTPLVTGPFHTIRNVAILNFNDGVYDSSESLGQNQINYNNSDTYKQIEGVNST GNSNLSLARKIQENRIDKDNLTENNITSSNNDSSIPTEKHRLAEYLSFVWLSGIIVFT VYFLIQYIKLRHMLKGAIKVDNNIWETSACDIPFVMPGIPSKIYIPVGLEGRQREDIL THEREHIRHFDPWIKCLATIALTVHWFNPFVWIAFSLMGKDIEMYCDERVLRGKGLNE KKQYSQTILDFSKKANGLPLAIGFAKNNTENRIKHILCSKKPHRIMNIVLVAVILACG VLFLTAGKKYAENTYNENKLNGTQRENNISDTEKTPASGKESASDNNAADDSKAENEA VTENQNSYTEEEEFWDEKLIVGTTFEPDPNLKKRILDAPDYASDWGSFHPVFEGNMTE NINLIGKTQHFLLYGTSNTESMIVKTPDNRYISAKVPYTSHYMFQPLVNEMDYDRDGE NELAIIIYVKHGTGCSIKTLFMVDKANDGKWYMYQLLENEYLPQLEAKFDTVYTEDSI KLLLDGKHVGLTKPMDNEFRNSSVNYKFHAGMQIQIHFVEDRIELNADLLGYSDTFFS GEFTGHRINADIAYLGEGKWELKNFRYKDINMDLVIEDALTMYFTGRTEELNQYYMAD GFHLKEIRKKSNDASVLNISYPVDNMDSGKVEAHATVRLDSSSSLINVTVSMKLTDSL NGTWKIVGIDVSGL" misc_feature complement(16287..>16790) /locus_tag="ClothDRAFT_1266" /note="Peptidase family M48; Region: Peptidase_M48; cl12018" /db_xref="CDD:187163" gene complement(17223..17585) /locus_tag="ClothDRAFT_1267" CDS complement(17223..17585) /locus_tag="ClothDRAFT_1267" /inference="protein motif:PFAM:PF03965" /note="PFAM: Penicillinase repressor; KEGG: swp:swp_3949 penicillinase repressor" /codon_start=1 /transl_table=11 /product="transcriptional repressor, CopY family" /protein_id="ZP_05429406.1" /db_xref="GI:256004426" /db_xref="InterPro:IPR001400" /db_xref="InterPro:IPR005650" /translation="MKYYLNDSEYRFMCIVWDVEPINSMELVRICYDKLGWKKSTTFT VIRNLCKKKILSNENAVVKALVSRNSIQKQEVRDFLDKKFQGSLPAFISAFLQDKKLT REEAEYLQKLIDDAKEDE" misc_feature complement(17241..17573) /locus_tag="ClothDRAFT_1267" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" gene 17893..18999 /locus_tag="ClothDRAFT_1268" CDS 17893..18999 /locus_tag="ClothDRAFT_1268" /inference="protein motif:PFAM:PF01547" /note="PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_591 periplasmic-iron-binding protein BitA" /codon_start=1 /transl_table=11 /product="extracellular solute-binding protein family 1" /protein_id="ZP_05429407.1" /db_xref="GI:256004427" /db_xref="InterPro:IPR006059" /translation="MKIKKSWLALILAALMAISVTACSGSKTETTKQDPTTKNQETNN NNNNNNNNNEENVLVVYTARSEELNKAVISEFEKETGIKVELVTAGTGELLKRVESEK DNPLGDILWAADRTMLAASEDLFMEYVSKEDGNMMEGFQNTTGYFSPAFADPAVFIVN TDLKGDIKIEGFEDLLNPKLKGKIAFGDPVNSSSAFQSLVAMLYAMGENNDPMSDKAW EFVDQFLKNLDGKMANSSSQVYKGVAEGEYIVGLTWEDPAAKYVKEGANVEVVFPKEG TIFPGESVQIIKNCKHPENAKKFVDFMLSEEVQNRVGSELTVRPLRKGAKLADYMTPQ SEIKLFSNYDEGWVAANKLAITNKFSEHLESSMD" sig_peptide 17893..17961 /locus_tag="ClothDRAFT_1268" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.492 at residue 23" misc_feature 18106..18975 /locus_tag="ClothDRAFT_1268" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398" /db_xref="CDD:187020" gene 19137..20240 /locus_tag="ClothDRAFT_1269" CDS 19137..20240 /locus_tag="ClothDRAFT_1269" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rle:pRL120171 putative ATP-binding component of ABC transporter" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429408.1" /db_xref="GI:256004428" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013611" /db_xref="InterPro:IPR017871" /translation="MSVAISIENVVKRFGKETVINGLSLEIKPGEFFTLLGPSGCGKT TLLRMIIGFNSIEGGQIKIDGKVINNIPTNKRNMGMVFQNYAIFPHMSVKDNIAFGLK NRKVPKAEIEKRVDEILKIVKIDHLKDRMPHKMSGGQQQRIALARAIVIHPEVLLMDE PLSNLDAKLRTEMRNAIKQIQQQVGITTVYVTHDQEEALAVSDRIAVMNGGVIQQIDT PKNIYQRPANTFVSTFIGLSNIMDGKLESNENGKALIRIGDYKFQMNNIKKDCGSNCP VKVSVRPEEFIINKETEEGIPVTVKSSVFLGVTTHYFVETKEGQEIEVIQSSDIGEII PNGKKVHLKVQVQKINVFSEDGSRSFIDREVRP" misc_feature 19137..20198 /locus_tag="ClothDRAFT_1269" /note="ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842" /db_xref="CDD:33633" misc_feature 19149..19844 /locus_tag="ClothDRAFT_1269" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature 19245..19268 /locus_tag="ClothDRAFT_1269" /note="Walker A/P-loop; other site" /db_xref="CDD:72971" misc_feature order(19254..19259,19263..19271,19383..19385,19611..19616, 19713..19715) /locus_tag="ClothDRAFT_1269" /note="ATP binding site; other site" /db_xref="CDD:72971" misc_feature 19374..19385 /locus_tag="ClothDRAFT_1269" /note="Q-loop/lid; other site" /db_xref="CDD:72971" misc_feature 19539..19568 /locus_tag="ClothDRAFT_1269" /note="ABC transporter signature motif; other site" /db_xref="CDD:72971" misc_feature 19599..19616 /locus_tag="ClothDRAFT_1269" /note="Walker B; other site" /db_xref="CDD:72971" misc_feature 19623..19634 /locus_tag="ClothDRAFT_1269" /note="D-loop; other site" /db_xref="CDD:72971" misc_feature 19701..19721 /locus_tag="ClothDRAFT_1269" /note="H-loop/switch region; other site" /db_xref="CDD:72971" misc_feature 19971..20162 /locus_tag="ClothDRAFT_1269" /note="TOBE domain; Region: TOBE_2; cl01440" /db_xref="CDD:163979" gene 20237..21892 /locus_tag="ClothDRAFT_1270" CDS 20237..21892 /locus_tag="ClothDRAFT_1270" /inference="protein motif:PFAM:PF00528" /note="PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_586 ABC transporter, membrane spanning protein" /codon_start=1 /transl_table=11 /product="binding-protein-dependent transport systems inner membrane component" /protein_id="ZP_05429409.1" /db_xref="GI:256004429" /db_xref="InterPro:IPR000515" /translation="MNTAKKKLNIWLVLALAILALFLIFVVYPIGLILYKSILMEDGT ISFSYFTKFFSKKFYWSTLVNSFKVTIASTLVSAVLGLIMAYLLRSIKIKGSKYLNIL IVISYLSPPFIGAYAWVQLLGRNGVITRILNSVFNAKLGGIYGFAGIVLVFSLQSFPL VYMYVSGALKNLDNSLNEAAESLGCSTVQRVWKVIVPLITPTLLASSLLVFMRVFSDF GTPMLIGEGYKTFPVLLYSQFMGEVSTDAHYAAALCVIVIVITLVLFFLQKYIGNRLT YSMSALKPMEPQKVTGIRNVLAHGFVYLVVLAAILPQLTVITTSFLETRGASYTGQFT LQNYKNIIMPKNISTITNTYLFGLAAIILVVILGVLISYLTVRKRSFLTSILDTLTMF PYIIPGSVLGISFLYAFNKKPLLLSGTAIIVIISLCIRRMPYTIRSSTAIIGQISPSV EEAAISLGSTEVKTFVKITVPMMMAGVLSGAIMSWITLISELSSSIILYTSKTQTLTV AIYTEVIRSNFGNAAAYSTVLTITSVLSLLLFFKVSGSEDISV" sig_peptide 20237..20332 /locus_tag="ClothDRAFT_1270" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.940) with cleavage site probability 0.716 at residue 32" misc_feature 20423..20953 /locus_tag="ClothDRAFT_1270" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature order(20471..20476,20483..20488,20501..20503,20531..20542, 20546..20575,20582..20587,20591..20593,20699..20704, 20708..20710,20714..20716,20723..20728,20732..20734, 20744..20749,20756..20758,20807..20809,20849..20854, 20861..20863,20882..20893,20900..20905,20942..20947) /locus_tag="ClothDRAFT_1270" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature order(20549..20593,20882..20899) /locus_tag="ClothDRAFT_1270" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature order(20591..20593,20684..20686,20900..20902,20936..20938, 20945..20947) /locus_tag="ClothDRAFT_1270" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature order(20759..20797,20813..20818,20828..20830) /locus_tag="ClothDRAFT_1270" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" misc_feature 21134..21787 /locus_tag="ClothDRAFT_1270" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cl00427" /db_xref="CDD:185990" gene 22003..23727 /locus_tag="ClothDRAFT_1271" CDS 22003..23727 /locus_tag="ClothDRAFT_1271" /inference="protein motif:PFAM:PF06580" /note="PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: gme:Gmet_2698 histidine kinase internal region" /codon_start=1 /transl_table=11 /product="signal transduction histidine kinase, LytS" /protein_id="ZP_05429410.1" /db_xref="GI:256004430" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR010559" /translation="MASNRYRSYVQRTFYRYTFSIILFLCILVILFLIINIKWLTTSK SQRNNAKIAEVLEQEIVSYKEGLKALANDYRIINLCKRQTKEQTANVNRLLYDFSNSQ EIRGVFTLVDLQGNLICSNLYKDNRNIFLQSFLYKSLVSKMLSDPQRTFLVPSRLNYS YNQTGDLLIGCTVKDGNEAVGFLFFELLDEEIYETVSRYNVDDVILTDQFNNLIFSIG RQSEDSMGKYPVGSSQFEKNQVDIIELNGKQYLIIKSILNDGTLYLYTLTSISFQQDL FRYAILFVVIMGILILTLLKPLTLLVTDKNLHAIEELRKSILEMGRGNMEYSLRPHVF EEFQELNDTFRQMVLQREELQKRNNELMERKRIMEIRQLEEKINPHFLFNVLETLRYE VMIDPAKASEMIMAFANIMRYNIYYRDTIVPLKTDIEHVKDYLMLQKMRYNRRLTYSI DIPEELMECKVPKLVIQPIVENALKHGMKNVETINVNITASVENENLRLSVEDNGSGI EPEILNELIKDLEREDVYKEHIGMYNSHRVIRLLYGPPYGLKIESTYGKGTVVNIILP INRGDDNE" misc_feature 23107..23352 /locus_tag="ClothDRAFT_1271" /note="Histidine kinase; Region: His_kinase; pfam06580" /db_xref="CDD:148281" misc_feature 23395..23697 /locus_tag="ClothDRAFT_1271" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature order(23404..23406,23416..23418,23425..23427,23503..23505, 23509..23511,23515..23517,23521..23526,23590..23598, 23653..23655,23659..23661,23674..23679,23683..23685) /locus_tag="ClothDRAFT_1271" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature 23416..23418 /locus_tag="ClothDRAFT_1271" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature order(23515..23517,23521..23523,23593..23595) /locus_tag="ClothDRAFT_1271" /note="G-X-G motif; other site" /db_xref="CDD:28956" gene 23720..24499 /locus_tag="ClothDRAFT_1272" CDS 23720..24499 /locus_tag="ClothDRAFT_1272" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; response regulator receiver; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="two component transcriptional regulator, AraC family" /protein_id="ZP_05429411.1" /db_xref="GI:256004431" /db_xref="InterPro:IPR000005" /db_xref="InterPro:IPR001789" /translation="MNKVLIVEDEDIMRKGLMFMPKWHEVDCIVVGEAVNGQDGLEKI QKYRPDIVIADINMPVMDGLEMLEKSIREYGYDAIIVSGYGEFEYARRGISLGVTEYL LKPIDYSKLYEAIRKIQAKRNADTNIKNAIRQIDAEKKKLGILEYKERKTGNRYVDFM IQTIHDNYHTRLALTDISEQCRMSCTYLNVKFKNETGYTFNDYLNRYRIQKAVDLLRE NQYKIYEIAEMVGFSDYKYFIKVFKKYIGCSPARFISENTD" misc_feature 23720..24271 /locus_tag="ClothDRAFT_1272" /note="Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707" /db_xref="CDD:33502" misc_feature 23732..24073 /locus_tag="ClothDRAFT_1272" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(23741..23746,23882..23884,23906..23908,23963..23965, 24020..24022,24029..24034) /locus_tag="ClothDRAFT_1272" /note="active site" /db_xref="CDD:29071" misc_feature 23882..23884 /locus_tag="ClothDRAFT_1272" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature order(23891..23896,23900..23908) /locus_tag="ClothDRAFT_1272" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature 24029..24037 /locus_tag="ClothDRAFT_1272" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature 24209..24334 /locus_tag="ClothDRAFT_1272" /note="Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165" /db_xref="CDD:143933" misc_feature 24230..24478 /locus_tag="ClothDRAFT_1272" /note="helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342" /db_xref="CDD:128636" gene complement(24725..25393) /locus_tag="ClothDRAFT_1273" CDS complement(24725..25393) /locus_tag="ClothDRAFT_1273" /EC_number="4.1.2.4" /inference="protein motif:TFAM:TIGR00126" /note="KEGG: vvy:VV0527 deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase" /codon_start=1 /transl_table=11 /product="deoxyribose-phosphate aldolase" /protein_id="ZP_05429412.1" /db_xref="GI:256004432" /db_xref="InterPro:IPR002915" /db_xref="InterPro:IPR011343" /translation="MNTQDILSHVDHTLLLQTATWPEIQALCDDAIKYQTASVCIPPC YVARAKEYVGDRMVICTVIGFPNGNMTTAAKVFETQDAIANGADEIDMVINIGALKNK EYDYVLKEIKAIKQACGERILKVIIETCLLTEEEKIVMCDLVTRSGADYIKTSTGFST AGATFEDIELFAKHVGPNVKIKAAGGISNFNDARKYIELGADRLGTSRLVKLMKSQSY DGLY" misc_feature complement(24773..25378) /locus_tag="ClothDRAFT_1273" /note="2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family. DERA belongs to the class I aldolases and catalyzes a reversible aldol reaction between acetaldehyde and glyceraldehyde 3-phosphate to generate 2-deoxyribose 5-phosphate. DERA is unique in...; Region: DeoC; cd00959" /db_xref="CDD:29952" misc_feature complement(order(25001..25003,25043..25048,25103..25105, 25109..25111,25136..25147,25160..25162,25175..25177, 25199..25201,25259..25267,25337..25339,25343..25345, 25349..25351)) /locus_tag="ClothDRAFT_1273" /note="intersubunit interface; other site" /db_xref="CDD:29952" misc_feature complement(order(24773..24781,24836..24844,24926..24928, 24935..24937)) /locus_tag="ClothDRAFT_1273" /note="active site" /db_xref="CDD:29952" misc_feature complement(24935..24937) /locus_tag="ClothDRAFT_1273" /note="catalytic residue; other site" /db_xref="CDD:29952" gene complement(25450..25866) /locus_tag="ClothDRAFT_1274" CDS complement(25450..25866) /locus_tag="ClothDRAFT_1274" /inference="protein motif:TFAM:TIGR01354" /note="TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; Cytidine and deoxycytidylate deaminase zinc-binding domain protein; KEGG: spe:Spro_3635 cytidine deaminase" /codon_start=1 /transl_table=11 /product="cytidine deaminase" /protein_id="ZP_05429413.1" /db_xref="GI:256004433" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR006262" /db_xref="InterPro:IPR013171" /translation="MTRSELISHALQARKQSYSPYSHFAVGAALLSKDGRLYTGCNIE NAAYTPSNCAERTAFFKAVSEGVREFSAIAIVGGPEGADTLALCAPCGVCRQVMMEFC DPKTFEVILAKDPQHYEIFTLEQILPMGFGPKDLEK" misc_feature complement(25495..25848) /locus_tag="ClothDRAFT_1274" /note="Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283" /db_xref="CDD:29826" misc_feature complement(order(25585..25587,25594..25596,25702..25710, 25735..25737,25741..25743,25789..25791,25795..25797)) /locus_tag="ClothDRAFT_1274" /note="active site" /db_xref="CDD:29826" misc_feature complement(order(25585..25587,25594..25599,25702..25710)) /locus_tag="ClothDRAFT_1274" /note="catalytic motif; other site" /db_xref="CDD:29826" misc_feature complement(order(25585..25587,25594..25596,25702..25704, 25708..25710)) /locus_tag="ClothDRAFT_1274" /note="Zn binding site; other site" /db_xref="CDD:29826" gene complement(25948..26883) /locus_tag="ClothDRAFT_1275" CDS complement(25948..26883) /locus_tag="ClothDRAFT_1275" /inference="protein motif:PFAM:PF02653" /note="PFAM: inner-membrane translocator; KEGG: hch:HCH_02312 uncharacterized ABC-type transport system, permease component" /codon_start=1 /transl_table=11 /product="inner-membrane translocator" /protein_id="ZP_05429414.1" /db_xref="GI:256004434" /db_xref="InterPro:IPR001851" /translation="MEELIKNLGLVINATLIATPPLLYAALGSTFSERSGVVNIGIEG MMTIGAFVGAAVAHFTGNAWLAFLCGGLVGALFGLIHAIACVSFGADQTISGTAINFL APGVAIFVCKALFEQSSNTPPLDTAQKLPKLFNGVFEVGSFWNNVLNTYVATYLAFVA VAIVWFIFYKTRFGMRLRAVGEHPKACETQGINVFRIRYIAVIASGFFAGLGGAYVTL CTVSQFRPEVIVGQGFIAIAAVIFGKFTPHGAMGACLLFGLCNGLKVLLGSGNVISPN LISMIPYVVTIITLVLFVGKSRVPAASGKPYLKQK" misc_feature complement(26014..26823) /locus_tag="ClothDRAFT_1275" /note="Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (; Region: TM_PBP1_transp_TpRbsC_like; cd06580" /db_xref="CDD:119322" misc_feature complement(26275..26331) /locus_tag="ClothDRAFT_1275" /note="TM-ABC transporter signature motif; other site" /db_xref="CDD:119322" gene complement(26884..28002) /locus_tag="ClothDRAFT_1276" CDS complement(26884..28002) /locus_tag="ClothDRAFT_1276" /inference="protein motif:PFAM:PF02653" /note="PFAM: inner-membrane translocator; KEGG: mxa:MXAN_5713 ABC transporter, permease protein" /codon_start=1 /transl_table=11 /product="inner-membrane translocator" /protein_id="ZP_05429415.1" /db_xref="GI:256004435" /db_xref="InterPro:IPR001851" /translation="MKHKNNQNNKPSQNILKIKAQRLIHQNALYTIIAIFFGFLVGGI FLWAAGFSPIEAYAKLFSSVFSRPKYLIWSVIYATPLIFTGLSVAFSYKIGVFNIGAE GQFVVGSLAALCVGILVDAPPGLHVLLCMLAAVAAGMLWSFLVAVLRVRFGINEVLSF IMFNWIAFYFSNYVVNTAAIHKVGGGEASKDIRESARILLPQSLQNIFQSNKANYGIF LAIIAAIVIWFILTKTTLGYKVQAVGLNPHAAKYGGINSNKTMYIAMSLSGALAALGG AVQLMGNSMRISQFAGQEGFGFQGITVALIASSHPIGCIFSGLFYGAMKYGGSKLNLI DAPTEVVDIIMGTIVLFIAISHVFRYLITRRLKNKEDK" sig_peptide complement(27856..28002) /locus_tag="ClothDRAFT_1276" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.965) with cleavage site probability 0.872 at residue 49" misc_feature complement(26944..27771) /locus_tag="ClothDRAFT_1276" /note="Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette...; Region: TM_PBP1_transp_TpRbsC_like; cd06580" /db_xref="CDD:119322" misc_feature complement(27205..27261) /locus_tag="ClothDRAFT_1276" /note="TM-ABC transporter signature motif; other site" /db_xref="CDD:119322" gene complement(27977..29539) /locus_tag="ClothDRAFT_1277" CDS complement(27977..29539) /locus_tag="ClothDRAFT_1277" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: scl:sce7755 sugar ABC transporter, ATP-binding protein" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429416.1" /db_xref="GI:256004436" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /translation="MEKTSHIDPNVVAVQMTDIVKKFGNFVANDHINLTVYKGEVHAI LGENGAGKSTLMNILYGLYKPTSGSISIFGSPVHIESPRHAIELGIGMVHQHFMLVEP FTVTENIILGMEPTKGMVVDIKKARRKVLELSERYGMHVDPDAKIEDISVGMQQRVEI LKVLYRGANILILDEPTASLTPQEIEELINIIHNLTADGKTVLLITHKLKEIKASADR CTIIRQGKYIGTVDVEAVSEHDLASMMVGRDVQFVVDKKPIEPGEVIIDIQDLHARDY RGVEVLKGLSLKVRRGEIVGLAGVDGNGQTELVEILTGLRKGESGKVIIGGKDLFNAD ARTLFDNGVSSIPADRQKHGLILDYSVAYNLVLQNYEQPPFSKRGILKKDAIYKHAAE LVEKFDVRGADGGTKEAGKLSGGNQQKVIIAREVTNDKDLLIAVNPTRGLDVGAIEFV HRYIVEQRNKNKAVLLVSFELDEIMSLSDRIEVIYSGNIVGSVPGHEADEKVLGLMMA GGTKNETQKQPE" misc_feature complement(28013..29506) /locus_tag="ClothDRAFT_1277" /note="ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845" /db_xref="CDD:33636" misc_feature complement(28850..29500) /locus_tag="ClothDRAFT_1277" /note="This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and...; Region: ABC_Carb_Monos_I; cd03216" /db_xref="CDD:72975" misc_feature complement(29381..29404) /locus_tag="ClothDRAFT_1277" /note="Walker A/P-loop; other site" /db_xref="CDD:72975" misc_feature complement(order(28919..28921,29015..29020,29255..29257, 29378..29386,29390..29395)) /locus_tag="ClothDRAFT_1277" /note="ATP binding site; other site" /db_xref="CDD:72975" misc_feature complement(29255..29266) /locus_tag="ClothDRAFT_1277" /note="Q-loop/lid; other site" /db_xref="CDD:72975" misc_feature complement(order(29063..29074,29132..29149)) /locus_tag="ClothDRAFT_1277" /note="ABC transporter signature motif; other site" /db_xref="CDD:72975" misc_feature complement(29015..29032) /locus_tag="ClothDRAFT_1277" /note="Walker B; other site" /db_xref="CDD:72975" misc_feature complement(28997..29008) /locus_tag="ClothDRAFT_1277" /note="D-loop; other site" /db_xref="CDD:72975" misc_feature complement(28913..28933) /locus_tag="ClothDRAFT_1277" /note="H-loop/switch region; other site" /db_xref="CDD:72975" misc_feature complement(28073..28756) /locus_tag="ClothDRAFT_1277" /note="This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (; Region: ABC_Carb_Monos_II; cd03215" /db_xref="CDD:72974" gene complement(29601..30443) /locus_tag="ClothDRAFT_1278" CDS complement(29601..30443) /locus_tag="ClothDRAFT_1278" /EC_number="1.97.1.4" /inference="protein motif:PRIAM:1.97.1.4" /note="PFAM: Radical SAM domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shl:Shal_0326 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="(Formate-C-acetyltransferase)-activating enzyme" /protein_id="ZP_05429417.1" /db_xref="GI:256004437" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR001989" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR017900" /translation="MVATVNKIIPFSTVDGPGNRTAIFLQGCNMNCLYCHNPETRCKC MHCGACVNSCPTGALSFEDEKVRYNCAKCVHCDSCIKACPHDSSPKTVDMTPEQVWRK VEKQIPFIRGITVSGGECTLYPEFLTELFILAQAHGLSTLIDSNGTLDFEHYPDLLAV TDGVMLDIKAFDCEEHKRVTGWSNQVVLKNARFLASKGKLFEVRTVVSPGLFDAEQTI TQIGDMLSSYLPIRPIRYKLISYRPMGVRPQYKETLQIPTRNQMEYYAGLLAAKGFKD IIII" misc_feature complement(29619..30413) /locus_tag="ClothDRAFT_1278" /note="pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145" /db_xref="CDD:182994" misc_feature complement(30183..>30350) /locus_tag="ClothDRAFT_1278" /note="RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409" /db_xref="CDD:187025" misc_feature complement(29676..30221) /locus_tag="ClothDRAFT_1278" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature complement(order(29751..29756,29826..29828,29949..29951, 30006..30014,30087..30092,30096..30098,30204..30212, 30216..30218)) /locus_tag="ClothDRAFT_1278" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene complement(30446..31975) /locus_tag="ClothDRAFT_1279" CDS complement(30446..31975) /locus_tag="ClothDRAFT_1279" /inference="similar to AA sequence:KEGG:CGSHiGG_05855" /note="KEGG: hiq:CGSHiGG_05855 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429418.1" /db_xref="GI:256004438" /translation="MERVNETRKKILDIIKSPILTHEQKVASLANTADSLLEVLDLPQ GLDELMNVPADRKCICDLNEGHAPLRPRYIIPDYAKFMKEGSRFLQLAPPTDLYEALN SLLIFYKHVPSVTNFPVYLGQLDTLLEPFMQDVDDTTAKKLLRGFLVHVDRTILDSFS HANIGPKPTRTGRLLLEVEAELTQAVPNLTLKYEEGVTDDDFAIQAVKTALRSAKPSF ANHRMFTQELGENYVIASCYNGLPLGGGSYTLCRLILGNIAKRAGGIEDFRTNQLPYV MDIMARYMDSRIRFEVEESGFFENNFLAREGFISRKRFTAMFGLVGLAECVNILLEKE GRPGRFGHDEYATELGESIIKQIYEFSEKHHNPYCEITGGHFLLHAQVGISEDQNISP GTRIPIGEEPDEMIDHLMVVNHFHKYFPSGTGDIFPIDVTVHQNPEYVLDIVKGSFRK ELRYLSFYEKNSDVIRITGYLVKRSEIEKLKSGQNVLQDTTALGMGAVMNGKILDRKV R" misc_feature complement(30449..31963) /locus_tag="ClothDRAFT_1279" /note="hypothetical protein; Provisional; Region: PRK10977" /db_xref="CDD:182879" misc_feature complement(<31262..>31699) /locus_tag="ClothDRAFT_1279" /note="Pyruvate formate lyase; Region: PFL; pfam02901" /db_xref="CDD:145845" misc_feature complement(30560..>31417) /locus_tag="ClothDRAFT_1279" /note="Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939" /db_xref="CDD:186877" gene complement(32045..33112) /locus_tag="ClothDRAFT_1280" CDS complement(32045..33112) /locus_tag="ClothDRAFT_1280" /inference="protein motif:PFAM:PF02608" /note="PFAM: basic membrane lipoprotein; KEGG: mxa:MXAN_5711 Bmp family lipoprotein" /codon_start=1 /transl_table=11 /product="basic membrane lipoprotein" /protein_id="ZP_05429419.1" /db_xref="GI:256004439" /db_xref="InterPro:IPR003760" /translation="MKKFLALLLSVIIVFSLTACGGKNSGNNSNNSSNNNSSNNTGGK KIKIGMVTDVGGVNDGSFNQSAWEGLQRAQKELGVEVRYAESATDADYAPNIEAFIDE GYDLIICVGYMLADATRKAAEANPNQKFAIIDDASIDLPNVTCLMFEQSQASYLVGLV AGKMTKTNKVGFVVGMVSQTMNEFGYGYLAGVKDANPNATILQFNANSFSSTETGKSA ATTMITNGADVIFHAAGGTGLGVIEGCKDAGKWAIGVDSDQSPLAPENILTSAMKRVD NACFDIAKAVKEGNVKPGIITYDLKSAGVDIAPTTTNLPKEVLDYVNQAKQDIINGKI TVPKTKAEFEAKYGNIYELDD" sig_peptide complement(33047..33112) /locus_tag="ClothDRAFT_1280" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.577 at residue 22" misc_feature complement(32072..32977) /locus_tag="ClothDRAFT_1280" /note="Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744" /db_xref="CDD:31930" misc_feature complement(32192..32974) /locus_tag="ClothDRAFT_1280" /note="Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354" /db_xref="CDD:107349" misc_feature complement(order(32294..32296,32345..32347,32408..32410, 32486..32488,32570..32572,32711..32713,32924..32926, 32951..32956)) /locus_tag="ClothDRAFT_1280" /note="ligand binding site; other site" /db_xref="CDD:107349" gene complement(33195..33905) /locus_tag="ClothDRAFT_1281" CDS complement(33195..33905) /locus_tag="ClothDRAFT_1281" /inference="protein motif:TFAM:TIGR00107" /note="TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: purine nucleoside phosphorylase ; K03784 purine-nucleoside phosphorylase" /codon_start=1 /transl_table=11 /product="purine nucleoside phosphorylase" /protein_id="ZP_05429420.1" /db_xref="GI:256004440" /db_xref="InterPro:IPR000845" /db_xref="InterPro:IPR004402" /translation="MSRVPTAHNAAVEGQIAKTVLMPGDPLRAKFIAETYLENVTCFN TVRNMLGFTGTYQGKPVSVMGHGMGIPSIGIYSYELFNFYDVDNIIRIGSAGALSDDL DLKDLVIAMGACTDSNYANQYQLPGTFAPIASYTLMQKAIEEAQKKGISVAIGNVLST DVFYNANKGANDAWKSMGVLCIEMEAAALYMNAAQAGKNALCILSISDHIYKGTELSA QERQLGFKNMIEVALGII" misc_feature complement(33198..33893) /locus_tag="ClothDRAFT_1281" /note="Phosphorylase superfamily; Region: PNP_UDP_1; cl00303" /db_xref="CDD:185889" misc_feature complement(33207..33884) /locus_tag="ClothDRAFT_1281" /note="Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820" /db_xref="CDD:32648" gene 34581..35324 /locus_tag="ClothDRAFT_1282" CDS 34581..35324 /locus_tag="ClothDRAFT_1282" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429421.1" /db_xref="GI:256004441" /translation="MMNDGKEKKNESNAESGSDYERIDDMFFRQINERRKEDPLIGAK LGAKEIFNTLLNAVRDSRGVHIETLICALGALAGYSCQASLRKEFVEIRGLSEEQVFT VIQAKNGKRYFFGDLINKPLFENQYSVWSLAAGIVQHMGVNIDFDILEIFKYVSATVG TENYGIPRIPEGHRTADVPINFVKAFWPLFLPRIEKYCASPREWPVLFGLAIQDGLLQ GKDVIDPSLALKIVMESAIPMAKAEIVFD" gene complement(35676..36530) /locus_tag="ClothDRAFT_1283" CDS complement(35676..36530) /locus_tag="ClothDRAFT_1283" /EC_number="1.18.6.1" /inference="protein motif:TFAM:TIGR01287" /note="KEGG: dal:Dalk_1522 nitrogenase iron protein; TIGRFAM: nitrogenase iron protein; PFAM: NifH/frxC-family protein" /codon_start=1 /transl_table=11 /product="nitrogenase iron protein" /protein_id="ZP_05429422.1" /db_xref="GI:256004442" /db_xref="InterPro:IPR000392" /db_xref="InterPro:IPR005977" /translation="MSKEIRQIAIYGKGGIGKSTTTQNLTAGLAESGKKIMVVGCDPK ADSTRLLLGTFAQRTVLDTLRETGEDVKLENIVRIGFGGIKCVESGGPEPGVGCAGRG IITSIGLLEQLGAYDDDLDYVFYDVLGDVVCGGFAMPIREGKAKEIYIVASGEMMALY AANNIAKGIAKFAQKGGVRLGGIICNSRNVDREIDLLRAFCAELGTQLIYFVPRDNVV QRAEINRKTVIEYAPDSQQADEYRRLAKAIDENTYFTIPKPLSQERLEEILLEYGLME SLKDDYRI" misc_feature complement(35712..36518) /locus_tag="ClothDRAFT_1283" /note="NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040" /db_xref="CDD:48369" misc_feature complement(35700..36515) /locus_tag="ClothDRAFT_1283" /note="nitrogenase iron protein; Region: nifH; TIGR01287" /db_xref="CDD:162286" misc_feature complement(order(36141..36146,36153..36155,36393..36395, 36399..36401,36405..36407,36474..36482,36486..36488, 36495..36497)) /locus_tag="ClothDRAFT_1283" /note="Nucleotide-binding sites; other site" /db_xref="CDD:48369" misc_feature complement(36474..36497) /locus_tag="ClothDRAFT_1283" /note="Walker A motif; other site" /db_xref="CDD:48369" misc_feature complement(36390..36410) /locus_tag="ClothDRAFT_1283" /note="Switch I region of nucleotide binding site; other site" /db_xref="CDD:48369" misc_feature complement(order(36132..36134,36237..36239)) /locus_tag="ClothDRAFT_1283" /note="Fe4S4 binding sites; other site" /db_xref="CDD:48369" misc_feature complement(36141..36155) /locus_tag="ClothDRAFT_1283" /note="Switch II region of nucleotide binding site; other site" /db_xref="CDD:48369" gene complement(36551..37354) /locus_tag="ClothDRAFT_1284" CDS complement(36551..37354) /locus_tag="ClothDRAFT_1284" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bpy:Bphyt_2099 ABC transporter related" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429423.1" /db_xref="GI:256004443" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /translation="MSKNLSVISDIILHIENVNYTYYDDAGNHVEVLRDINLSVRRGE FLSIIGSSGCGKTTLLRLIAGLDKPETGTLILNGEQISGPDPERGYVFQHGGLFQWLT VEKNIATGLKARHVYRENKHRIAHYIDLIGLKGFEKCYPHQLSGGMAQRVAIARALIN NPKVLLLDEPMSALDSFTRSDIQDKLLELHKENKTTMILVTHDVDEAIYLSDRIVVMT PRPGKISEIMEINLPHPRHRGGTKFLSLRRNILEKLHLASALPQPEYTI" misc_feature complement(36572..37321) /locus_tag="ClothDRAFT_1284" /note="ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116" /db_xref="CDD:31313" misc_feature complement(36659..37318) /locus_tag="ClothDRAFT_1284" /note="NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars...; Region: ABC_NrtD_SsuB_transporters; cd03293" /db_xref="CDD:73052" misc_feature complement(37184..37207) /locus_tag="ClothDRAFT_1284" /note="Walker A/P-loop; other site" /db_xref="CDD:73052" misc_feature complement(order(36749..36751,36848..36853,37076..37078, 37181..37189,37193..37198)) /locus_tag="ClothDRAFT_1284" /note="ATP binding site; other site" /db_xref="CDD:73052" misc_feature complement(37076..37087) /locus_tag="ClothDRAFT_1284" /note="Q-loop/lid; other site" /db_xref="CDD:73052" misc_feature complement(36896..36925) /locus_tag="ClothDRAFT_1284" /note="ABC transporter signature motif; other site" /db_xref="CDD:73052" misc_feature complement(36848..36865) /locus_tag="ClothDRAFT_1284" /note="Walker B; other site" /db_xref="CDD:73052" misc_feature complement(36830..36841) /locus_tag="ClothDRAFT_1284" /note="D-loop; other site" /db_xref="CDD:73052" misc_feature complement(36743..36763) /locus_tag="ClothDRAFT_1284" /note="H-loop/switch region; other site" /db_xref="CDD:73052" gene complement(37351..38418) /locus_tag="ClothDRAFT_1285" CDS complement(37351..38418) /locus_tag="ClothDRAFT_1285" /inference="protein motif:PFAM:PF00528" /note="PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mch:Mchl_1328 binding-protein-dependent transport systems inner membrane component" /codon_start=1 /transl_table=11 /product="binding-protein-dependent transport systems inner membrane component" /protein_id="ZP_05429424.1" /db_xref="GI:256004444" /db_xref="InterPro:IPR000515" /translation="MYDLVKLQSPTSSELKVKQQYGKLKTVSAQNWSTNFVLTLAGFA VAIAANILVKQVANVEIKTYFVAGIPFTFNLLYRLVLVVIILIYAGMGIFSYFDPVRR EKFSRQAPFRFAMGLAITAWDILGTKLLLLPQPFFPGPAKILESFLIEGDFILQNTLY SIKLFLAGFTLGVVFGVGTGILIGWFPKVYYWVYPILKITGVIPAVAWMPFALTLFPS PFSAAVFLIVICAWFSIAALTAQGIQSTPKYQFEVARTLGAKTPFLIFHVAVPQAMPQ IFTGISNANGFAFTTLVMAEMMGQPGGLGYYINLSKVWSAYYKVFASILVMALLFSLI MKILGLIQANVLRWQKGWVKE" misc_feature complement(37420..37863) /locus_tag="ClothDRAFT_1285" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature complement(order(37420..37425,37432..37437,37444..37449, 37453..37458,37465..37470,37498..37503,37528..37533, 37540..37551,37570..37572,37579..37584,37624..37626, 37675..37677,37684..37689,37699..37701,37705..37710, 37720..37722,37726..37728,37732..37737,37780..37782, 37786..37791,37798..37827,37831..37842)) /locus_tag="ClothDRAFT_1285" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature complement(order(37534..37551,37780..37824)) /locus_tag="ClothDRAFT_1285" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature complement(order(37468..37470,37498..37500,37507..37509, 37531..37533,37750..37752,37780..37782)) /locus_tag="ClothDRAFT_1285" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature complement(order(37603..37605,37615..37620,37636..37674)) /locus_tag="ClothDRAFT_1285" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" gene complement(38499..39560) /locus_tag="ClothDRAFT_1286" CDS complement(38499..39560) /locus_tag="ClothDRAFT_1286" /inference="protein motif:SMART:SM00062" /note="SMART: extracellular solute-binding protein family 3; KEGG: rpi:Rpic_4459 NMT1/THI5 like domain protein" /codon_start=1 /transl_table=11 /product="extracellular solute-binding protein family 3" /protein_id="ZP_05429425.1" /db_xref="GI:256004445" /db_xref="InterPro:IPR001638" /translation="MKGFIKLISAVALFSIFIGLFSGCGRTNTGGTQDNGKTGTSSAE YKYGKIDIPGKDGSLCGAPIYIAYEKGFFKQEGFDVNLISADTETRKIGLNNGTIPIV NGDFQFFPSIENNVKVKVVDGLHYGCIKLIVPKDSPIQGVQDLRGKKISVDEIGGTPH QVASVWLEKNGISAKQEDGEVTFLPFSDGNLAVEALRKGEVDVAALWDPFGSVQEKTG NYRVILDISKDEPFAGKYCCFLYASEKLLDEKPEQVAALLRAYRAAQNWISENPEEAV DIIINGKYAQIEDRELAIKLIKSYQYPSYAEREKNKTQVRDNVYYFAEQLNQIGYLKT DPDTFTKNAYVEVDINLGL" misc_feature complement(38547..39560) /locus_tag="ClothDRAFT_1286" /note="ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715" /db_xref="CDD:31059" sig_peptide complement(39471..39560) /locus_tag="ClothDRAFT_1286" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.966) with cleavage site probability 0.409 at residue 30" misc_feature complement(38862..39398) /locus_tag="ClothDRAFT_1286" /note="Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and...; Region: PBPb; cd00134" /db_xref="CDD:29040" misc_feature complement(order(38940..38942,39087..39089,39225..39227, 39300..39302)) /locus_tag="ClothDRAFT_1286" /note="substrate binding pocket; other site" /db_xref="CDD:29040" misc_feature complement(order(38961..38963,38979..38981,38991..38993)) /locus_tag="ClothDRAFT_1286" /note="membrane-bound complex binding site; other site" /db_xref="CDD:29040" misc_feature complement(38862..38873) /locus_tag="ClothDRAFT_1286" /note="hinge residues; other site" /db_xref="CDD:29040" gene complement(39585..40901) /locus_tag="ClothDRAFT_1287" CDS complement(39585..40901) /locus_tag="ClothDRAFT_1287" /EC_number="2.5.1.49" /inference="protein motif:PRIAM:2.5.1.49" /note="PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: geo:Geob_2499 O-acetylhomoserine aminocarboxypropyltransferase" /codon_start=1 /transl_table=11 /product="O-acetylhomoserine aminocarboxypropyltransferase" /protein_id="ZP_05429426.1" /db_xref="GI:256004446" /db_xref="InterPro:IPR000277" /db_xref="InterPro:IPR001597" /translation="MANELEKTAYRFDTQRLRAGYDPKEHNYAVSPPIYQTTSFDFRD VEHAKALFGLRELGNLYTRIGNPTVAVLEQRVAALDGASGAVALASGMAAISYTLLNV AEGGGRILTSPYLYGGSADSFKKVYPKFGITFDFAKNIENPEKLSEEIKPDTKAIYVE SISNPNAALLDIDAIAKVAHEHGIPLIVDNTVATPYLYNPISHGADIVVYSATKGLTG HGNVIAGLVLESGKFNWQSDKFPQFSEKYYTLRDINDNYRSFLEVFPEAPFTGRIRFN YLNYFGAALSPFDAYLVLIGLETLSERVEKQVRNASILAEYLKSHKSVEWVRYPGLKD SPYYELAQRDFPKGAGGILSFGFKGTTAQRETFLNSVKLFHYHVNIGDARSLIVNSPQ TTHSELEPDEKKFADIPENLIRISAGLEDPADLIADLEQAFEKAYI" misc_feature complement(39600..40871) /locus_tag="ClothDRAFT_1287" /note="OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326" /db_xref="CDD:130393" misc_feature complement(39600..40817) /locus_tag="ClothDRAFT_1287" /note="CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614" /db_xref="CDD:99738" misc_feature complement(order(39795..39797,40035..40040,40044..40046, 40077..40079,40233..40235,40239..40241,40263..40265, 40530..40532,40539..40541,40554..40556,40623..40628, 40632..40637,40713..40715,40719..40721,40776..40781, 40785..40796)) /locus_tag="ClothDRAFT_1287" /note="homodimer interface; other site" /db_xref="CDD:99738" misc_feature complement(order(40233..40235,40260..40265,40269..40271, 40335..40337,40422..40424,40554..40556,40626..40634)) /locus_tag="ClothDRAFT_1287" /note="substrate-cofactor binding pocket; other site" /db_xref="CDD:99738" misc_feature complement(order(40260..40265,40269..40271,40326..40328, 40335..40337,40554..40556,40626..40634)) /locus_tag="ClothDRAFT_1287" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99738" misc_feature complement(40260..40262) /locus_tag="ClothDRAFT_1287" /note="catalytic residue; other site" /db_xref="CDD:99738" gene complement(41173..42048) /locus_tag="ClothDRAFT_1288" CDS complement(41173..42048) /locus_tag="ClothDRAFT_1288" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: rpt:Rpal_2906 radical SAM domain protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05429427.1" /db_xref="GI:256004447" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /translation="MAFTYEDLKKNHPCFAAGAKNNKGRVHLPVSYGCNIACNFCKRD INDTDNRPGVASGIITPQEAVDAVRRAVELCPDITVAGVAGPGDTLATPYALQTFRLI KQEFPHIIKCMSTNGLLLPEYADEIIDVGIDSLTVTVNAVDPEIQAQICEGIVYHGKR YTGIEAAKILIQNQLAGIKKVSQSGITVKVNTVLIPEINADHVVEVAKTVAQHGAKIY NIIPLIPQHKLSWCSTPGCDLISKVRSEAQAYINVFRHCQRCRADAAGIPGGKDISSS LYIRPVKLENTFSHG" misc_feature complement(41374..41967) /locus_tag="ClothDRAFT_1288" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature complement(order(41380..41385,41470..41472,41635..41637, 41701..41709,41785..41790,41794..41796,41914..41916, 41926..41931,41935..41937,41941..41943,41947..41949)) /locus_tag="ClothDRAFT_1288" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene complement(42061..42396) /locus_tag="ClothDRAFT_1289" CDS complement(42061..42396) /locus_tag="ClothDRAFT_1289" /inference="protein motif:PFAM:PF02579" /note="PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: geo:Geob_2529 dinitrogenase iron-molybdenum cofactor biosynthesis protein" /codon_start=1 /transl_table=11 /product="Dinitrogenase iron-molybdenum cofactor biosynthesis protein" /protein_id="ZP_05429428.1" /db_xref="GI:256004448" /db_xref="InterPro:IPR003731" /translation="MSYRIGFASIDGTVIDQHFGSARYWQIYDVDKEARFVETRKTAA KCQGHCEGGFDHLLSVLEDCDAIFVLKIGQAAAAVMIAKGKRVFEATGEVEEILAQLV GGRLHEEGG" misc_feature complement(42094..42387) /locus_tag="ClothDRAFT_1289" /note="This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme; Region: NifX_NifB; cd00562" /db_xref="CDD:29644" gene complement(42410..43753) /locus_tag="ClothDRAFT_1290" CDS complement(42410..43753) /locus_tag="ClothDRAFT_1290" /EC_number="1.18.6.1" /inference="protein motif:PRIAM:1.18.6.1" /note="PFAM: oxidoreductase/nitrogenase component 1; KEGG: rpa:RPA2637 nitrogenase iron-molybdenum protein subunit NifK-like protein" /codon_start=1 /transl_table=11 /product="Nitrogenase" /protein_id="ZP_05429429.1" /db_xref="GI:256004449" /db_xref="InterPro:IPR000510" /translation="MSRSGLIEQERFTCAIGALQTVVAIPRAVPILHSGPGCGEMIAG FFERSTGYAGGSTSPCTNFTEKEVVFGGINRLRDIIENTYKVLDTDLQVVLTGCTAGI VGDDVDSLVSEFAQKGKPIVSVETAGFKATNFEAHSLVVNAIIDQYVSRFEDENKPKS QKNTVNLIASIPYQDPFWKGNLAEYKRLLAGIGLKANVLFGPQSGGVKEWQSIPTALF NILVSPWYGKPIADHLKSKYGQEYTWFHHIPIGANQTEAFLNQVVEFAIEQGADIDKE SAQEFIRHESHAYYEEIDNLATFLLEFRYGLPNHAHILHDAGYVVALSKFLLHEVGIV PKEQFITDATPEKFHEAIRADLKSTSDKKEIPLYFEPDAGKAQEILRGIHHKGRGLII GSGWDKELAKEKGYDFLSAALPSPYRLVLTTNYAGFTGGLRVIEDIYQTVLSTYA" misc_feature complement(42425..43735) /locus_tag="ClothDRAFT_1290" /note="The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia. This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent...; Region: Oxidoreductase_nitrogenase; cl02775" /db_xref="CDD:186532" misc_feature complement(42425..43714) /locus_tag="ClothDRAFT_1290" /note="Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148" /db_xref="CDD:143916" gene complement(43750..45225) /locus_tag="ClothDRAFT_1291" CDS complement(43750..45225) /locus_tag="ClothDRAFT_1291" /inference="protein motif:PFAM:PF00148" /note="PFAM: oxidoreductase/nitrogenase component 1; KEGG: rpt:Rpal_2908 nitrogenase" /codon_start=1 /transl_table=11 /product="oxidoreductase/nitrogenase component 1" /protein_id="ZP_05429430.1" /db_xref="GI:256004450" /db_xref="InterPro:IPR000318" /db_xref="InterPro:IPR000510" /translation="MSKINLSLPEVQIREIRINSITGYQGDAKELVEAREFGLKDKER SFSQCLGCATSKAACMTVLIQDAAVISHGPVGCASCLHEFAFTYRVNYPLRGIERPTP RRIFSTNLKEKDTVYGGNIKLANTIREVYERTHANAIFVLTTCAAGIIGDDVESVCNE AEEELGIPVVAIFCEGFRSKVWTTGFDAAYHGIARKLIQKPRRRRDDMINVINFWGSD VFYEWFAPFGAKPNYIIPFSTVNGLKYASEAAATVQACSTLGSYLGAVLEQDFGVPEI PAAPPYGIAQTDRWFRALGKILGKEEIAEKIIAEKKKEYLPKIEALREKLAGKTAYVT AGAAHGHALLDVLGELGIKAVGAAIFHHDPIYDSGREENDQLAQRVADYGNVFNYNVC NKQEFELVNALNRLRPDVLLARHGGMTLWGAKLGIPSLLIGDEHYSMGYEGLVNYGER ILEVIENDEFVKNLEKHAINPYTKWWLEQPPYYFLKGGTGK" misc_feature complement(43855..45099) /locus_tag="ClothDRAFT_1291" /note="The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia. This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent...; Region: Oxidoreductase_nitrogenase; cl02775" /db_xref="CDD:186532" misc_feature complement(43861..45072) /locus_tag="ClothDRAFT_1291" /note="Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148" /db_xref="CDD:143916" gene complement(45170..45709) /locus_tag="ClothDRAFT_1292" CDS complement(45170..45709) /locus_tag="ClothDRAFT_1292" /inference="protein motif:PFAM:PF00583" /note="PFAM: GCN5-related N-acetyltransferase; KEGG: lpc:LPC_2170 hypothetical protein" /codon_start=1 /transl_table=11 /product="GCN5-related N-acetyltransferase" /protein_id="ZP_05429431.1" /db_xref="GI:256004451" /db_xref="InterPro:IPR000182" /translation="MDLHIREADISDSALVLSFIKELAEFEGMGKEVTTTEAELRESL FQKRQANVLIAEIDGNPAAFALFYPVYSTFSGRQNLFLEDLFVKEEYRGKGIGKALMK QLAKKALQMGAKRLDWYVLEDNKSGSRFYKHLGAVPLLDRRTYRMSEKSLESLANGVM TNVKNKFIPSGSTDKGNSY" misc_feature complement(45266..45694) /locus_tag="ClothDRAFT_1292" /note="Acetyltransferases [General function prediction only]; Region: RimI; COG0456" /db_xref="CDD:30804" misc_feature complement(45362..45556) /locus_tag="ClothDRAFT_1292" /note="N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301" /db_xref="CDD:173926" misc_feature complement(order(45416..45421,45449..45457)) /locus_tag="ClothDRAFT_1292" /note="Coenzyme A binding pocket; other site" /db_xref="CDD:173926" gene complement(45814..46485) /locus_tag="ClothDRAFT_1293" CDS complement(45814..46485) /locus_tag="ClothDRAFT_1293" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vha:VIBHAR_05403 ABC transporter ATPase subunit" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429432.1" /db_xref="GI:256004452" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /translation="MLLEVSNLSKEYIRSNRPFFAVRDVHLKMKAGDFAIIIGRSGSG KTTLLNLIGGLISPTGGHVSIDGCDIMSLKDRELSSFRNSYIGYIPQGHSILSNLSVF DNVRLPHYLQKRQGDVNKRALSLLEQVGIAHLANAYPQHLSGGELRRVTIARALMNKP KLLLADEPTNDLDAQTTYEVMQLFSDIANEGTAVLLVTHDLSTIHYGKHVYQMDNGKL KSHNT" misc_feature complement(45832..46482) /locus_tag="ClothDRAFT_1293" /note="ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136" /db_xref="CDD:31331" misc_feature complement(45832..46479) /locus_tag="ClothDRAFT_1293" /note="This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE). They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255" /db_xref="CDD:73014" misc_feature complement(46348..46371) /locus_tag="ClothDRAFT_1293" /note="Walker A/P-loop; other site" /db_xref="CDD:73014" misc_feature complement(order(45889..45891,45985..45990,46213..46215, 46345..46353,46357..46362)) /locus_tag="ClothDRAFT_1293" /note="ATP binding site; other site" /db_xref="CDD:73014" misc_feature complement(46213..46224) /locus_tag="ClothDRAFT_1293" /note="Q-loop/lid; other site" /db_xref="CDD:73014" misc_feature complement(46033..46062) /locus_tag="ClothDRAFT_1293" /note="ABC transporter signature motif; other site" /db_xref="CDD:73014" misc_feature complement(45985..46002) /locus_tag="ClothDRAFT_1293" /note="Walker B; other site" /db_xref="CDD:73014" misc_feature complement(45967..45978) /locus_tag="ClothDRAFT_1293" /note="D-loop; other site" /db_xref="CDD:73014" misc_feature complement(45883..45903) /locus_tag="ClothDRAFT_1293" /note="H-loop/switch region; other site" /db_xref="CDD:73014" gene complement(46487..47698) /locus_tag="ClothDRAFT_1294" CDS complement(46487..47698) /locus_tag="ClothDRAFT_1294" /inference="protein motif:PFAM:PF02687" /note="PFAM: protein of unknown function DUF214; KEGG: msl:Msil_3893 protein of unknown function DUF214" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF214" /protein_id="ZP_05429433.1" /db_xref="GI:256004453" /db_xref="InterPro:IPR003838" /translation="MMAYALTSNRISFLNLRKKSFRTFALILVVAILSFALFGGTVLS FSFRNGLRSVEARLGADLIVVPLGHGKQQESILLTGEPSYFYFNKEIVQKLQEVEGIS KLSTQFYLISLSTGCCSLPVQIVGFDPATDFSIQPWIQETLGGNLENGAVIVGSDIMI EDNKHIKFFDKEYPVAAKLDKTGTGLDQSVFATMETLKDLYSGAKEKGFNFLEDTDPD TFISSVLIKVREGYNIDQVITNIRRKTDGVQIVRTQNLITGISKSLGNIITFFNVFAL VLLGVTLVILTVVFSASANERKKEFAIMRILGATRKKLAAVLIWESLYISVSGGAIGT ILAAIFVFPFNVFIGDSIGLPYIQPSLLWIIAILLGTLLVAFSLGPIASAYSAVKVSR SQTYLTLREGE" sig_peptide complement(47579..47698) /locus_tag="ClothDRAFT_1294" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.803 at residue 40" misc_feature complement(46499..47668) /locus_tag="ClothDRAFT_1294" /note="ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591" /db_xref="CDD:34229" misc_feature complement(46526..47038) /locus_tag="ClothDRAFT_1294" /note="Predicted permease; Region: FtsX; cl11418" /db_xref="CDD:187029" gene complement(47670..48107) /locus_tag="ClothDRAFT_1295" CDS complement(47670..48107) /locus_tag="ClothDRAFT_1295" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429434.1" /db_xref="GI:256004454" /translation="MMKNKVLSPIVYLIFGVLLTLGPYSIFPVCKASMMAMRCQATAK AELVLGILTIAVGVLMLLINHRKFRIGLNIAAIPIGILAFLFPNSITGVCSKVHMTCR ALTLPVLSLTGIALVVFAGINTVYLWRFESKGEIYDGICINFE" gene complement(48116..49024) /locus_tag="ClothDRAFT_1296" CDS complement(48116..49024) /locus_tag="ClothDRAFT_1296" /inference="protein motif:PFAM:PF00291" /note="PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: hhe:HH0063 cysteine synthase" /codon_start=1 /transl_table=11 /product="Pyridoxal-5'-phosphate-dependent protein beta subunit" /protein_id="ZP_05429435.1" /db_xref="GI:256004455" /db_xref="InterPro:IPR001216" /db_xref="InterPro:IPR001926" /translation="MIYDDMQQLIGNTPLVRLRHSGFPDGVRVYAKLELYNPSGSVKD RIGKYMIEDAEKRGVLVPGSTIVEGTAGNTGLGIAFAALNRGYRLIMVVPTKFSQEKQ ALLRALGAEVINTPREEGMLGAERKAEELRQSIPKAVSLEQFRNPANPLAHYETTGPE IWEDLGADIDYFVAGAGSGGTYAGIVRYLKEQKPDIKGILADPIGSTMGGGEHGDYDI EGIGNDFIPETMDMSLVDEVIKVSDDEAFTETRLLARNEGIIAGSSSGANLAAVRKLA MRIQRGTIVTVLPDRGERYLSKNLFL" misc_feature complement(48131..49021) /locus_tag="ClothDRAFT_1296" /note="Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031" /db_xref="CDD:30381" misc_feature complement(48134..48994) /locus_tag="ClothDRAFT_1296" /note="CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine...; Region: CBS_like; cd01561" /db_xref="CDD:107204" misc_feature complement(order(48137..48139,48146..48148,48176..48178, 48245..48253,48257..48265,48533..48538,48701..48706, 48713..48718,48725..48730,48776..48778,48785..48787, 48911..48913,48917..48919,48935..48937,48974..48982)) /locus_tag="ClothDRAFT_1296" /note="dimer interface; other site" /db_xref="CDD:107204" misc_feature complement(order(48155..48160,48233..48235,48365..48367, 48482..48499,48806..48808,48896..48898)) /locus_tag="ClothDRAFT_1296" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:107204" misc_feature complement(48896..48898) /locus_tag="ClothDRAFT_1296" /note="catalytic residue; other site" /db_xref="CDD:107204" gene complement(49021..50184) /locus_tag="ClothDRAFT_1297" CDS complement(49021..50184) /locus_tag="ClothDRAFT_1297" /EC_number="2.5.1.48" /inference="protein motif:PRIAM:2.5.1.48" /note="PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: hhe:HH0062 cystathionine gamma-synthase" /codon_start=1 /transl_table=11 /product="Cystathionine gamma-synthase" /protein_id="ZP_05429436.1" /db_xref="GI:256004456" /db_xref="InterPro:IPR000277" /db_xref="InterPro:IPR001597" /translation="MAHYKHIESAVIHGGIYGDFHTGSVNTPIYQTSTFEQDGLGKPR SNWEYSRTGNPTRAALEALIAELEGGSRGFAFSSGMAAIDAVLHLFQSGDSVIISDNV YGGTFRILDKIFKQYGLNYKIVDTTDLAALESAFTSDVKALLLESPANPLLKVTDIAA AAEIARSKGALTVVDNTFMTPYLQRPLELGADIVVHSATKYLGGHSDVIAGLVIVKDG ELAEKLHFIQNAVGAVAGPFDSFLLIRSIKTLAVRMEAHVANAEKLAEALKSNPAVKN VYYPGLKSAQGYEIQKRQAKNGGAMISFELHNNYDINRFFEGLELIALAESLGGVESL VCHPSSMTHASVPKEIREKIGITDTLIRLSVGIENYDDLKNDLFSAIKGARVL" misc_feature complement(49039..50163) /locus_tag="ClothDRAFT_1297" /note="Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053" /db_xref="CDD:144590" misc_feature complement(49039..50118) /locus_tag="ClothDRAFT_1297" /note="CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614" /db_xref="CDD:99738" misc_feature complement(order(49234..49236,49468..49473,49477..49479, 49507..49509,49558..49560,49564..49566,49588..49590, 49852..49854,49861..49863,49876..49878,49942..49947, 49951..49956,50032..50034,50038..50040,50074..50079, 50083..50094)) /locus_tag="ClothDRAFT_1297" /note="homodimer interface; other site" /db_xref="CDD:99738" misc_feature complement(order(49558..49560,49585..49590,49594..49596, 49660..49662,49747..49749,49876..49878,49945..49953)) /locus_tag="ClothDRAFT_1297" /note="substrate-cofactor binding pocket; other site" /db_xref="CDD:99738" misc_feature complement(order(49585..49590,49594..49596,49651..49653, 49660..49662,49876..49878,49945..49953)) /locus_tag="ClothDRAFT_1297" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99738" misc_feature complement(49585..49587) /locus_tag="ClothDRAFT_1297" /note="catalytic residue; other site" /db_xref="CDD:99738" gene 50542..50739 /locus_tag="ClothDRAFT_1298" CDS 50542..50739 /locus_tag="ClothDRAFT_1298" /inference="protein motif:PFAM:PF02082" /note="PFAM: protein of unknown function UPF0074; KEGG: pst:PSPTO_1422 rrf2 family protein" /codon_start=1 /transl_table=11 /product="transcriptional regulator, BadM/Rrf2 family" /protein_id="ZP_05429437.1" /db_xref="GI:256004457" /db_xref="InterPro:IPR000944" /translation="MRISAKGRYALAAVISMAQQYNNGEYITVISISEKLGISKIFLE QVFSSLKKAKIVSSTKGAQGG" misc_feature 50542..>50736 /locus_tag="ClothDRAFT_1298" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" gene 51444..52265 /locus_tag="ClothDRAFT_1299" CDS 51444..52265 /locus_tag="ClothDRAFT_1299" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pfl:PFL_0241 D-methionine ABC transporter, ATP-binding protein" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429438.1" /db_xref="GI:256004458" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /translation="MSKLTLCEMGVMDDYIQISGLHKTFHTRSGPIQVLKGIDLTVRK GEIFGIIGFSGAGKSTLARCINRLETPDSGSIKVGGVEILNLSKKQLLQERKKIGMIF QTFNLFEAKTVYHNISYPLEISKIPKPEIRKRVLETAELVGLSDKLNAYPGGLSGGQK QRVGIARALVSRPNLLISDEATSALDPQTTLQILDLLKEINRTTGITILMITHELDAI RYTCDRMAVLEDGKIIEVGTVREIFNNPLSRTGALFTKVFTEFQRITEFENGSGI" misc_feature 51489..52181 /locus_tag="ClothDRAFT_1299" /note="MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein; Region: ABC_MetN_methionine_transporter; cd03258" /db_xref="CDD:73017" misc_feature 51489..52181 /locus_tag="ClothDRAFT_1299" /note="ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126" /db_xref="CDD:31323" misc_feature 51597..51620 /locus_tag="ClothDRAFT_1299" /note="Walker A/P-loop; other site" /db_xref="CDD:73017" misc_feature order(51606..51611,51615..51623,51750..51752,51978..51983, 52080..52082) /locus_tag="ClothDRAFT_1299" /note="ATP binding site; other site" /db_xref="CDD:73017" misc_feature 51741..51752 /locus_tag="ClothDRAFT_1299" /note="Q-loop/lid; other site" /db_xref="CDD:73017" misc_feature 51906..51935 /locus_tag="ClothDRAFT_1299" /note="ABC transporter signature motif; other site" /db_xref="CDD:73017" misc_feature 51966..51983 /locus_tag="ClothDRAFT_1299" /note="Walker B; other site" /db_xref="CDD:73017" misc_feature 51990..52001 /locus_tag="ClothDRAFT_1299" /note="D-loop; other site" /db_xref="CDD:73017" misc_feature 52068..52088 /locus_tag="ClothDRAFT_1299" /note="H-loop/switch region; other site" /db_xref="CDD:73017" gene 52305..53015 /locus_tag="ClothDRAFT_1300" CDS 52305..53015 /locus_tag="ClothDRAFT_1300" /inference="protein motif:PFAM:PF00528" /note="PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: wsu:WS1944 ABC transporter permease" /codon_start=1 /transl_table=11 /product="binding-protein-dependent transport systems inner membrane component" /protein_id="ZP_05429439.1" /db_xref="GI:256004459" /db_xref="InterPro:IPR000515" /translation="MSLLDTPIWEVIKGSFAPDIWVRLVPAVGETLYMTVVSSIIMLV FGLLLGILLTVTNPDGLVPMKILYTGSGWLINALRSLPQMIMIILMIPVARLFFGKSY GTNACIISIAASCIPMYARIVENSLLEISKGKIEAAKSIGSTNFQIIFRILIPETLPS LIRGFTVAVIAVISMTALAGMFGAGGIGDIAVRFGYQRFQHDVLFASVYVLIALVQLV QWIGNFTSKQILKKRNLI" misc_feature <52653..52949 /locus_tag="ClothDRAFT_1300" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature order(52656..52658,52665..52670,52674..52676,52686..52691, 52698..52700,52749..52751,52791..52796,52803..52805, 52824..52835,52842..52847,52875..52880,52908..52913, 52920..52925,52929..52934,52941..52946) /locus_tag="ClothDRAFT_1300" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature order(52701..52739,52755..52760,52770..52772) /locus_tag="ClothDRAFT_1300" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" misc_feature order(52842..52844,52869..52871,52878..52880,52908..52910) /locus_tag="ClothDRAFT_1300" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" gene 53037..53921 /locus_tag="ClothDRAFT_1301" CDS 53037..53921 /locus_tag="ClothDRAFT_1301" /inference="protein motif:PFAM:PF03180" /note="PFAM: NLPA lipoprotein; KEGG: pfl:PFL_0071 D-methionine-binding lipoprotein MetQ" /codon_start=1 /transl_table=11 /product="NLPA lipoprotein" /protein_id="ZP_05429440.1" /db_xref="GI:256004460" /db_xref="InterPro:IPR004872" /translation="MKKHNVILIILTLILALGLLAGCSKEGDSKKSTVSSDIPASDSN ANPSPSQETITIKGIADLVPHSELIEYVAPRLKEQGIIVELVATAADNTTNEKLAKGE IDFNFFQHEPYLKEWNKVNGYNLVNAGDIHVEPITAYSDKYSSKEEIPDNAVVAIPND GTNEYRALRILEENGFIKLNPQTANSLTASVSDIAEYLRPIRIVELDSAQIIPTKDDY DFFITNTNKALEAKITSARLFSEGSDSPYANIIAVREEDLNNPAIVALVKALQSEDVR QYITDTYNGAVIPAKLDN" sig_peptide 53037..53117 /locus_tag="ClothDRAFT_1301" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.381 at residue 27" misc_feature 53223..53906 /locus_tag="ClothDRAFT_1301" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398" /db_xref="CDD:187020" gene 54228..54755 /locus_tag="ClothDRAFT_1302" CDS 54228..54755 /locus_tag="ClothDRAFT_1302" /inference="protein motif:TFAM:TIGR00589" /note="TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: eca:ECA2454 methylated DNA--protein-cysteine methyltransferase" /codon_start=1 /transl_table=11 /product="methylated-DNA/protein-cysteine methyltransferase" /protein_id="ZP_05429441.1" /db_xref="GI:256004461" /db_xref="InterPro:IPR001497" /db_xref="InterPro:IPR014048" /translation="MIYKYYYKTPDGFSDMLMTSDGEYLTGLWFDGSRGASKHISDCE EKLLPVFEDTIKWLDIYFSGKSPDFIPKYRIANLTDFRREVIDRMLEIPFGETRTYGE IAKVIAKKRGTAKMSSRAVGRAVGWNPICIIIPCHRVVGANSSLTGYGGGISNKVALL RHENNDMSKFTVPKK" misc_feature 54228..54719 /locus_tag="ClothDRAFT_1302" /note="Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350" /db_xref="CDD:30699" misc_feature 54468..54719 /locus_tag="ClothDRAFT_1302" /note="The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445" /db_xref="CDD:119438" misc_feature order(54468..54473,54525..54530,54564..54566,54576..54578, 54582..54587,54591..54593,54600..54605,54609..54611, 54633..54635,54648..54650,54669..54671) /locus_tag="ClothDRAFT_1302" /note="DNA binding site" /db_xref="CDD:119438" misc_feature order(54525..54527,54633..54638,54642..54644,54714..54716) /locus_tag="ClothDRAFT_1302" /note="active site" /db_xref="CDD:119438" gene 55286..55858 /locus_tag="ClothDRAFT_1303" CDS 55286..55858 /locus_tag="ClothDRAFT_1303" /inference="protein motif:PFAM:PF01613" /note="PFAM: flavin reductase domain protein FMN-binding; KEGG: gur:Gura_2846 flavin reductase domain-containing protein" /codon_start=1 /transl_table=11 /product="flavin reductase domain protein FMN-binding" /protein_id="ZP_05429442.1" /db_xref="GI:256004462" /db_xref="InterPro:IPR002563" /translation="MEKISIGPENKLCPQTLFLYGTYKEDGTPNFGLFCWFSYCWSGE LGVMACIAGEKLTKDRIRANKVFSANLVSESLLHLADYLGNTEGYNSGKMNIPIEVER GAVLNVPVLKNSPWVFELEVQQSVLLHDAEVFLCKIRNTLVAKELKDNSISVDERLRM AAPVMWVGEGQYYTLNYTALGKTGDWKDLG" misc_feature 55349..55729 /locus_tag="ClothDRAFT_1303" /note="Flavin Reductases; Region: FlaRed; cl00801" /db_xref="CDD:186194" gene 56108..56500 /locus_tag="ClothDRAFT_1304" CDS 56108..56500 /locus_tag="ClothDRAFT_1304" /inference="similar to AA sequence:KEGG:PFDG_02325" /note="KEGG: hypothetical protein similar to merozoite antigen erythrocyte-binding ligand" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429443.1" /db_xref="GI:256004463" /translation="MKKEFESEKSTLYDIKDDEERTKKANELKKKSLEIEKLVWKVKT QEEFAEELKCALISAKTALRDLKKAFPDGKIDPETKLFIEKREKKIARIEKDFEEGNK TPEELLKASFKKHQFKQKSFCRPGQQVR" gene complement(56954..57274) /locus_tag="ClothDRAFT_1305" CDS complement(56954..57274) /locus_tag="ClothDRAFT_1305" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: bid:Bind_0985 oxalate decarboxylase" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429444.1" /db_xref="GI:256004464" /translation="MFFDKGDYSEHNTFSISELFAHMPIDLLSANFGVPEETFKNIPK KEVYITDSGDPGTLESQTVDSPTGKVPLSYNTSMSFARYRQSKVTEEPFKFLTVAIFL PAKL" misc_feature complement(<57038..>57268) /locus_tag="ClothDRAFT_1305" /note="bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404" /db_xref="CDD:132445" gene 57868..58539 /locus_tag="ClothDRAFT_1306" CDS 57868..58539 /locus_tag="ClothDRAFT_1306" /inference="protein motif:PFAM:PF08242" /note="PFAM: Methyltransferase type 12; Methyltransferase type 11; KEGG: ank:AnaeK_3069 methyltransferase type 12" /codon_start=1 /transl_table=11 /product="Methyltransferase type 12" /protein_id="ZP_05429445.1" /db_xref="GI:256004465" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR013217" /translation="MTIEEQFNLIAKEYDCNRRKFIPCFDDYYESITKLIISNIDTPS RVLDLGAGTGLLTYYWYKECPSAEYVLVDIADEMLEISRKRFAGIDRIQHKILDYSKD LPEGNFDAIISALSIHHLEDMQKEELFRNIYNKLPLGGVFVNYDQFCAGTSNMNKWFD SYWEKQLYNSGLTDRDIELWKERRKLDKECSVETEIEMLYKCNFSEVKCLYSYHKFSV IAAIK" misc_feature 57868..58467 /locus_tag="ClothDRAFT_1306" /note="SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500" /db_xref="CDD:30846" misc_feature 58000..58296 /locus_tag="ClothDRAFT_1306" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature order(58012..58032,58084..58089,58156..58164,58207..58209) /locus_tag="ClothDRAFT_1306" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" gene 58748..59494 /locus_tag="ClothDRAFT_1307" CDS 58748..59494 /locus_tag="ClothDRAFT_1307" /inference="protein motif:PFAM:PF00378" /note="PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mmw:Mmwyl1_3101 enoyl-CoA hydratase-isomerase" /codon_start=1 /transl_table=11 /product="Enoyl-CoA hydratase/isomerase" /protein_id="ZP_05429446.1" /db_xref="GI:256004466" /db_xref="InterPro:IPR001753" /translation="MKYSTIQYRQVKDGIGLITLNRPEKRNAINIQMRIEISDCLCEL EQSSDINVVIFTGAGSSFSAGFDLNEFNNPSIFDALFESSSKYHRYIWKFSKPTIAAI NGAAMGGGFDLATLCDIRICSDSATFGHPEVKFGAPPLYTPLRWIVKDGIARELCLTG RKIDAKEALRIGLVSEITNSSDLLQRAIEIGETILEAPSDTIKYIKSYFISNAEKGFE ESFLIEHDKAFQDILLPKAKSGFFLQNGRK" misc_feature 58775..59479 /locus_tag="ClothDRAFT_1307" /note="enoyl-CoA hydratase; Provisional; Region: PRK06688" /db_xref="CDD:180658" misc_feature 58775..59329 /locus_tag="ClothDRAFT_1307" /note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase...; Region: crotonase-like; cd06558" /db_xref="CDD:119339" misc_feature order(58823..58825,58829..58831,58925..58927,58937..58951, 59060..59062,59066..59074,59138..59143,59150..59152) /locus_tag="ClothDRAFT_1307" /note="substrate binding site; other site" /db_xref="CDD:119339" misc_feature order(58943..58945,59072..59074) /locus_tag="ClothDRAFT_1307" /note="oxyanion hole (OAH) forming residues; other site" /db_xref="CDD:119339" misc_feature order(59012..59014,59036..59038,59099..59110,59144..59155, 59165..59173,59180..59185,59198..59203,59207..59212, 59216..59221,59228..59230,59261..59263,59270..59272, 59315..59317,59324..59329) /locus_tag="ClothDRAFT_1307" /note="trimer interface; other site" /db_xref="CDD:119339" gene complement(59567..60001) /locus_tag="ClothDRAFT_1308" CDS complement(59567..60001) /locus_tag="ClothDRAFT_1308" /inference="similar to AA sequence:KEGG:LmjF15.0740" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429447.1" /db_xref="GI:256004467" /translation="MKKVAKLSFFYSMLGLFFGAFYREFTKINGFTGKTVLSGVHPHI LVLGAIFFLIVLLLEKSFELSKNKNFNKFFITYNIGLLLSFIMMAIRGCIEVLKLEIS TMIDSSISGMAGLGHIIMTIAYILFFIILLNRINVADNNKIK" misc_feature complement(59630..60001) /locus_tag="ClothDRAFT_1308" /note="Protein of unknown function (DUF2871); Region: DUF2871; pfam11070" /db_xref="CDD:151515" gene 60386..61519 /locus_tag="ClothDRAFT_1309" CDS 60386..61519 /locus_tag="ClothDRAFT_1309" /inference="protein motif:PFAM:PF00037" /note="PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvm:DvMF_0593 4Fe-4S ferredoxin iron-sulfur binding domain protein" /codon_start=1 /transl_table=11 /product="4Fe-4S ferredoxin iron-sulfur binding domain protein" /protein_id="ZP_05429448.1" /db_xref="GI:256004468" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR001525" /translation="MEKAKVYFSDFRTVPFGDGLPTKLKKLIKKAGISQIDMDGKFVA IKMHFGELGNISYLRPNYARAVVDVVKELGGKPFLTDCNTMYPGKRKNALEHLECAWE NGFTPLTVGCPILIGDGLKGTDDIAVPVKGGQYVKEARIGRAIMDADVFISLTHFKGH EMTGFGGAIKNIGMGCGSRAGKKEQHSNGKPHIDQHLCRGCRSCLKECANNALVFDTV HKKMTVDKENCVGCGRCLGSCNFDAISFEDDAAIEQLNCRMAEYAKAVVDGRPCFHIS LVVDVSPYCDCHGENDVPILPDLGMFASFDPVALDQACVDACLKATPLPGSRLTDNMN KPDFVDHHDHFINTTPESEWRSCLEHAERIGLGTRDYELIVVK" misc_feature 60395..61513 /locus_tag="ClothDRAFT_1309" /note="Uncharacterized Fe-S center protein [General function prediction only]; Region: COG2768" /db_xref="CDD:32630" misc_feature 60479..>60943 /locus_tag="ClothDRAFT_1309" /note="Domain of unknown function (DUF362); Region: DUF362; cl00879" /db_xref="CDD:120200" gene 61657..61839 /locus_tag="ClothDRAFT_1310" CDS 61657..61839 /locus_tag="ClothDRAFT_1310" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429449.1" /db_xref="GI:256004469" /translation="MVILIEDDFMFFGRHEDHYDFLIVLGKAEREKFEAVKHEFPLEI QQLMNVNAPCTMVNGC" gene 63632..65377 /locus_tag="ClothDRAFT_1311" CDS 63632..65377 /locus_tag="ClothDRAFT_1311" /inference="protein motif:TFAM:TIGR00459" /note="TIGRFAM: aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); GAD domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: ech:ECH_0334 aspartyl-tRNA synthetase" /codon_start=1 /transl_table=11 /product="aspartyl-tRNA synthetase" /protein_id="ZP_05429450.1" /db_xref="GI:256004470" /db_xref="InterPro:IPR002312" /db_xref="InterPro:IPR004115" /db_xref="InterPro:IPR004364" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR004524" /db_xref="InterPro:IPR006195" /translation="MAEIYRTKTMNQITEEDIGSVLKIAGWVENIRDHGGVSFIDLRD MYGVMQVVFRNIEFPKGIRKEECLSIEGVIEKRDEETYNPKIPTGTIELVAQKVTVLG RVYRDLPFEVATSKEIREEVRLKYRYLDLRNRKVKDNILFRSQVISFLRQKMTEMGFV EIQTPILSASSPEGARDYIVPSRKHKGKFYALPQAPQIYKQLLMVSGFDKYFQIAPCF RDEDARADRSPGEFYQLDFEMSFATQEDVFRVGEEVLTATFKKFAPEGYEITEAPFPV FSYKQAMLEFGTDKPDLRNPLRIIDVTDFFQRCAFKPFHNKTVRAIKVHADMSKGFHE KLLEYALSIGMGGLGYLEVQEDMTYKGPIDKYIPQELKGELAQISGLIPGDVIFFIAD KEKLACKYAGLIRNELGKRLDICEKNAYRFCYVNDFPMYEMDEETGKIEFTHNPFSMP QGGLEALNTKGPLDILAYQYDIVCNGVELSSGAVRNHDLDIMVKAFEIAGYDEETLKK KFGALYNAFQYGAPPHAGMAPGIERMIMLLRNEENIREVVAFPMNSNAQDLLCGAPGE VTEQQLREVHIKIRN" misc_feature 63644..65374 /locus_tag="ClothDRAFT_1311" /note="aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476" /db_xref="CDD:179042" misc_feature 63647..64039 /locus_tag="ClothDRAFT_1311" /note="EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317" /db_xref="CDD:58587" misc_feature order(63647..63649,63656..63658,63710..63712,63764..63766, 63935..63937,63941..63943,63947..63949) /locus_tag="ClothDRAFT_1311" /note="dimer interface; other site" /db_xref="CDD:58587" misc_feature order(63719..63721,63725..63733,63746..63748,63779..63781, 63818..63820,63860..63862,63878..63880,63905..63907, 63956..63958) /locus_tag="ClothDRAFT_1311" /note="anticodon binding site; other site" /db_xref="CDD:58587" misc_feature 64049..>64492 /locus_tag="ClothDRAFT_1311" /note="Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of the...; Region: AspRS_core; cd00777" /db_xref="CDD:73228" misc_feature order(64058..64066,64073..64075,64082..64087,64094..64096, 64103..64114,64118..64138,64157..64159,64166..64180, 64190..64201,64244..64249,64256..64261,64277..64279, 64289..64291,64322..64324,64352..64354,64367..64369) /locus_tag="ClothDRAFT_1311" /note="homodimer interface; other site" /db_xref="CDD:73228" misc_feature 64124..64138 /locus_tag="ClothDRAFT_1311" /note="motif 1; other site" /db_xref="CDD:73228" misc_feature order(64148..64156,64214..64216,64220..64222,64229..64231, 64286..64288,64292..64294,64307..64315,64325..64327, 64331..64333) /locus_tag="ClothDRAFT_1311" /note="active site" /db_xref="CDD:73228" misc_feature 64283..64294 /locus_tag="ClothDRAFT_1311" /note="motif 2; other site" /db_xref="CDD:73228" misc_feature 64574..64828 /locus_tag="ClothDRAFT_1311" /note="GAD domain; Region: GAD; pfam02938" /db_xref="CDD:145868" misc_feature <64877..65296 /locus_tag="ClothDRAFT_1311" /note="Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268" /db_xref="CDD:185874" misc_feature order(65063..65068,65078..65080,65207..65212,65216..65221, 65228..65230) /locus_tag="ClothDRAFT_1311" /note="active site" /db_xref="CDD:29813" misc_feature order(65219..65221,65228..65230) /locus_tag="ClothDRAFT_1311" /note="motif 3; other site" /db_xref="CDD:29813" gene 65440..65733 /locus_tag="ClothDRAFT_1312" CDS 65440..65733 /locus_tag="ClothDRAFT_1312" /inference="protein motif:TFAM:TIGR00135" /note="TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; KEGG: gsu:GSU3383 glutamyl-tRNA(Gln) amidotransferase, C subunit" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase, C subunit" /protein_id="ZP_05429451.1" /db_xref="GI:256004471" /db_xref="InterPro:IPR003837" /translation="MKISKTEVEKLAKLAKLSFSDEELERFTAEFDEIIAFADTINQS IEGGTEQIRSVGARMVSFDDLRPDEVVPSLPNEKILSNVEGYNGFFGLERSKK" misc_feature 65440..65709 /locus_tag="ClothDRAFT_1312" /note="Glu-tRNAGln amidotransferase C subunit; Region: Glu-tRNAGln; cl00495" /db_xref="CDD:186035" gene 65730..67190 /locus_tag="ClothDRAFT_1313" CDS 65730..67190 /locus_tag="ClothDRAFT_1313" /EC_number="3.5.1.4" /inference="protein motif:TFAM:TIGR00132" /note="KEGG: gur:Gura_4324 aspartyl/glutamyl-tRNA amidotransferase subunit A; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, A subunit; PFAM: Amidase" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase, A subunit" /protein_id="ZP_05429452.1" /db_xref="GI:256004472" /db_xref="InterPro:IPR000120" /db_xref="InterPro:IPR004412" /translation="MRTGISELAKRLQSREISAMELTKAYIGAIEKLNPTINAYVYLT FDTAMKAAEKADQRLKEGGAPLLCGIPMALKDNICTDGLNTTCCSKILKGFKPYYDAT VWEKLKAHGAVLLGKTNMDEFAMGSTSETSCYGAPLNPRNTNYVTGGSSGGSAAAVCA NLAVYSLGSDTGGSIRQPASFCGVVGLKPTYGAVSRYGLIAYGSSLDQIGPMTNSVKD AAIVFDAIKGGDRRDQTSVDYDYGSYLAECLDRDVKGMRIGVAEEFFDGINPEIKSKI EEAIKLFERNGAVIENIRLPALKLALPVYYIIACAEASSNLGRYDGIRYGYRTSSYTS IEDMIVKTRSEGFGDEVKRRIMLGTYVLSSGYYDAYYKKACLIREEINREFDAVFEKC DVLVAPTAPNTAFPLNYKGAGPVEMYLSDICTVPVNIAGVPAISVPCGEDSNGLPVGM QIIGKKFDEATVLQAAHFYEQSAGEVIGVYEGGARI" misc_feature 65742..67151 /locus_tag="ClothDRAFT_1313" /note="Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154" /db_xref="CDD:30503" misc_feature 65763..67139 /locus_tag="ClothDRAFT_1313" /note="GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cl11426" /db_xref="CDD:187035" gene 67187..68602 /locus_tag="ClothDRAFT_1314" CDS 67187..68602 /locus_tag="ClothDRAFT_1314" /inference="protein motif:TFAM:TIGR00133" /note="TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB region; GatB/Yqey domain protein; GatB central domain protein; KEGG: sat:SYN_00309 aspartyl/glutamyl-tRNA amidotransferase subunit B" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase, B subunit" /protein_id="ZP_05429453.1" /db_xref="GI:256004473" /db_xref="InterPro:IPR003789" /db_xref="InterPro:IPR004413" /db_xref="InterPro:IPR006075" /db_xref="InterPro:IPR006107" /translation="MNYEIVCGIETHIELATKTKIFCGCTTEFGGEPNTHCCPVCTGQ PGSLPILNQKVVEYAIKAGLALNCKINTKSHMDRKNYVYPDLPKAYQISQYDEPLCEK GYIELDSGKRIGITRIHIEEDAGKLVHENGYTYIDYNRSGVPLIEIVSEPDISSAEEA REYAEKLQLIMRYIGISDCKMQEGSMRCDVNLSLRKPGDSRFGVRTEIKNINSLSFIQ KAVMAEAERQADILDAGGTVVQQTMRYDEATNSVSPMRDKENSDDYRYFPDPDILRFS INDEKVEEIRASLPELPFDKLKRYVNVLGLPEATARQIFRYRKVAEFFEGALAEGASV KNAANLIVGTIFSNMDTEEEKELFDIRISSAQFAALVKLADEKKINIGVAQSTLQKML ESGKPVEEFIKPEDLASISDEELESLCKEAIDANPKAVADVRSGKDKAINVMFGYIMK KTGGKADIRKVEVLLRKLIGQ" misc_feature 67187..68590 /locus_tag="ClothDRAFT_1314" /note="aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477" /db_xref="CDD:180111" misc_feature 67196..68041 /locus_tag="ClothDRAFT_1314" /note="GatB/GatE catalytic domain; Region: GatB_N; pfam02934" /db_xref="CDD:145865" misc_feature 68189..68593 /locus_tag="ClothDRAFT_1314" /note="GatB domain; Region: GatB_Yqey; cl11497" /db_xref="CDD:159498" gene 69113..71218 /locus_tag="ClothDRAFT_1315" CDS 69113..71218 /locus_tag="ClothDRAFT_1315" /inference="protein motif:PFAM:PF00120" /note="PFAM: glutamine synthetase catalytic region; KEGG: gbm:Gbem_3079 glutamine synthetase catalytic region" /codon_start=1 /transl_table=11 /product="glutamine synthetase catalytic region" /protein_id="ZP_05429454.1" /db_xref="GI:256004474" /db_xref="InterPro:IPR008146" /translation="MGKCIDEINCGMFGSAVFSDAVMQERLPKPVYKKLKKTIKEGLP LDPDIAEVVACVMKDWAVEMGATHFTHWFQPLTGVTAEKHDSFLSPTGDGKAIMEFSG KELIKGEPDASSFPSGGLRATFEARGYTAWDCTSPAFVKDKTLYIPTAFCSYTGEALD LKTPLLRSMEALSKQALRILRLFGDTTTKRVVTTLGPEQEYFLVDKEKFMQRKDLIYT GRTLFGAKPPKGQELEDHYFGIIKEKISRFMHDLDAELWKLGVSAKTKHNEVAPAQHE LAPVFATTNIATDHNQLTMEIMKKVADRHGLACLLHEKPFAGVNGSGKHNNWSISTDD GRNLLDPGTTPSENAQFLIFLVAVIKAVDDYADLLRFSVATAGNDHRLGANEAPPAIM SIFLGDELTNVIEEIETGVVKNNGTSRTLEIGVSTLPVLPKDNTDRNRTSPFAFTGNK FEFRSVGSSQSIATPNFIINTIVAETLSQIADRLEKAQDFKAEVNAVVKEIIKNHKRI IFNGNNYSEEWVAEAERRGLPNLKTTVDAIPVLIAEKNIKVLEKHGVLNRAEVLSRYE ICLENYVKTIRIEALTMIEMASRQILPASLAYVGKVADTVASLKAAGADSSFAKEELD ELVSLTSSLKAAIDKLSAKLEEVDAHEGDSLEHARAYKDVIIPLMNELRAFADKLETM VDASLWPIPTYGDLLFSVI" misc_feature 69146..71212 /locus_tag="ClothDRAFT_1315" /note="Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968" /db_xref="CDD:33749" misc_feature 69146..69616 /locus_tag="ClothDRAFT_1315" /note="Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437" /db_xref="CDD:152871" misc_feature 69698..70276 /locus_tag="ClothDRAFT_1315" /note="Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120" /db_xref="CDD:143894" gene 71434..72564 /locus_tag="ClothDRAFT_1316" CDS 71434..72564 /locus_tag="ClothDRAFT_1316" /inference="protein motif:PFAM:PF01381" /note="PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: swp:swp_1457 helix-turn-helix motif protein" /codon_start=1 /transl_table=11 /product="transcriptional regulator, XRE family" /protein_id="ZP_05429455.1" /db_xref="GI:256004475" /db_xref="InterPro:IPR001387" /translation="MKMKEINIARTIVKMRREKGLTQEDIANYIGVSKASVSKWETGQ SYPDITFLPQLATLFNISIDELMGYEPQMSKEDIRKLYVKLSADFASKPFDEVLNSCR EIAKKYFSCFYLLFHIGLLLVNNSTESGDKEKTLSVLSEAKELFVRVKTESDDAELVQ LSLCMEACCALMMGNPNEVIELLEGTRKKIISSETILASAYQMIGKSKEAKMTLQAAI YQHMCNLFSALTDYLLLCTDTPEQFDKTLKRANDIAEAFDLKKLHPSLLMKLYIIAAQ GYMMLGSKEKSLEILEKYTELVTGDIYPLQLKGDEYFNLIDQWIEELDLGNALPRDEK IIRKSMADGVINNPAFTILADEIRFRRIAEKLKNNCYQQDAP" misc_feature 71458..71631 /locus_tag="ClothDRAFT_1316" /note="Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093" /db_xref="CDD:28977" misc_feature order(71470..71472,71482..71484,71557..71559) /locus_tag="ClothDRAFT_1316" /note="non-specific DNA binding site; other site" /db_xref="CDD:28977" misc_feature order(71479..71481,71554..71556) /locus_tag="ClothDRAFT_1316" /note="salt bridge; other site" /db_xref="CDD:28977" misc_feature order(71500..71505,71536..71538,71545..71547,71557..71562) /locus_tag="ClothDRAFT_1316" /note="sequence-specific DNA binding site; other site" /db_xref="CDD:28977" gene 72605..72811 /locus_tag="ClothDRAFT_1317" CDS 72605..72811 /locus_tag="ClothDRAFT_1317" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429456.1" /db_xref="GI:256004476" /translation="MDSAMLKEYLPFLIPLVIAQYALAITALVHVLRHPRYRFGNKVM WVLIVLFIQFIGPALYFAFGRGEE" gene 72812..73729 /locus_tag="ClothDRAFT_1318" CDS 72812..73729 /locus_tag="ClothDRAFT_1318" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppd:Ppro_1661 ABC transporter related" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429457.1" /db_xref="GI:256004477" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /translation="MGVLEIRQLYKSFGHHEVLKGLDMDVPEHSIFGFVGQNGAGKTT TMKIILGLLKPDSGSVTVCGEKVTYGESKANRHIGFLPDVPEFYGYMNPMEYLKLCGE IAGLSKTQIKSRSEELLELVGLKDQKKRISGFSRGMKQRLGIAQALLNEPKLLICDEP TSALDPIGRKEILDILLAAKGKTTIVFSTHILSDVERICDRIAVLHDGKLALCGTLSE IKERHRLHGFILEFENEEAASCFENTEELKQPSISLSRDGSTVKVFMKDGGMDGHFLL GVLSQKRIVPLKFAVMEPTLESLFMEVVR" misc_feature 72812..73726 /locus_tag="ClothDRAFT_1318" /note="ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131" /db_xref="CDD:31326" misc_feature 72821..73441 /locus_tag="ClothDRAFT_1318" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature 72917..72940 /locus_tag="ClothDRAFT_1318" /note="Walker A/P-loop; other site" /db_xref="CDD:72971" misc_feature order(72926..72931,72935..72943,73058..73060,73283..73288, 73379..73381) /locus_tag="ClothDRAFT_1318" /note="ATP binding site; other site" /db_xref="CDD:72971" misc_feature 73049..73060 /locus_tag="ClothDRAFT_1318" /note="Q-loop/lid; other site" /db_xref="CDD:72971" misc_feature 73211..73240 /locus_tag="ClothDRAFT_1318" /note="ABC transporter signature motif; other site" /db_xref="CDD:72971" misc_feature 73271..73288 /locus_tag="ClothDRAFT_1318" /note="Walker B; other site" /db_xref="CDD:72971" misc_feature 73295..73306 /locus_tag="ClothDRAFT_1318" /note="D-loop; other site" /db_xref="CDD:72971" misc_feature 73367..73387 /locus_tag="ClothDRAFT_1318" /note="H-loop/switch region; other site" /db_xref="CDD:72971" gene 73726..74490 /locus_tag="ClothDRAFT_1319" CDS 73726..74490 /locus_tag="ClothDRAFT_1319" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429458.1" /db_xref="GI:256004478" /translation="MKGYFAFLKKEFFEYTKTYKLFIMLMIFIIFGITNPLIAKLMPE IVGSLVTDGVVITLPEPTAYDAWAQFFKNATQMGLFVMVILFSGVLSSELSKGTLINL LTKGLSRTAVILSKYTCMVSVWTISISLCFGLTYGYTAYLFPQGETSNLLFSVFCLWL FGLFLLAALLFSATLTRSSYGGLLITGAVVVVCMVMNIIPDVHRYNPISLATDNMGLI MNSTEVSSLYSTIMISCLLSLIFVFLSVVIFRKKQL" gene 74966..76603 /locus_tag="ClothDRAFT_1320" CDS 74966..76603 /locus_tag="ClothDRAFT_1320" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429459.1" /db_xref="GI:256004479" /translation="MSPSFRKLIFVLCAVLVIGGVCLYWINSSKMTISINEVPMKVSK SLIITHDTKIYVDVLKMLSLQEIPFHTGDFGITVLLSGSKVVRLNTEDNIAVINGETL DLTDEDYIYNKQKLYLTEETYRRLFDQAIIYLPEEKVKFATYDIGGFKIPQDLTFEEY LSMTPEECQKLVVRNSYNKKILESQVNTVPGDELNPVVKDAYNQVVWSFDLYRQFQFY NWHIGLDDSEGLSGYLLCSNAETILRQFERMKILREIANIKEFTTKDIEYINRINTLY NAMDFQKIKLLGPAIESYIDRLDPSTEGWDVYKSSAEKALEQFNKTFKVEKIDKLNIP AWAEFDSYYVSLKYFPYAEQEKNLHEMLDQILDKVPDGINNAIEWSENYSEIEKIILM VYPEWKSYLPGEELINGLKNGSLKKEVKTLGKVVKIYDGINLFNDVLNLMDTERDNDF FAEVKKSKVDSASNILNKIINPAQMIKSGLEMGNANLVSMGGLLGLEFFIAQEVTSRI EKLGKFVSGMVLMSMDTDSMDDVYNGKISLEEYLDGE" gene 77324..77701 /locus_tag="ClothDRAFT_1321" CDS 77324..77701 /locus_tag="ClothDRAFT_1321" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: ppw:PputW619_3128 flavin reductase domain-containing protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429460.1" /db_xref="GI:256004480" /translation="MLNFPSYDICDKCVQTIKNNGFDDDEITLSGLTAEKAKTVNAPR IAECFLSIECEFLWEREHFEGSPNVTVALRATHICMDSDHYDQNKLGRYGKTGYMYNV HSPRNPETGEVTPDCFGALELYR" misc_feature <77327..>77488 /locus_tag="ClothDRAFT_1321" /note="Flavin Reductases; Region: FlaRed; cl00801" /db_xref="CDD:186194" ORIGIN 1 atttcctttg attttccgga tgaaaaagat attatttcaa ataaagatgt gtttgttaat 61 atgatggatt tgttttcctc caagtatccc gacaaaggct atctgattgt ggtggatgag 121 tttcttgact atcttggtgg tcgtaaagac caagaaatta ttttcgatct gaactttatg 181 cgtgaaatag ggtaaattgt taaaatttcc cgcttaagag ttattttcgg agtacaggag 241 aaactttttg acaatcctaa cttttcattt gtatcaaata ctttaaacaa gataaaagac 301 agatttgagc aggttattat tcgcaaggag gatactgctt atgtcgtatc tgaaaaaata 361 ctgaaaaaga cgccggaaca gaaagcattg atacgggagc atttgcaaaa gttctgcagc 421 ttgtactcca atatgtcgga acgcatggaa gagtacgtaa acctgtttcc tattcatcct 481 tcttatattg aagtatttaa caagatttat attattgaga atcgtcatat acttaaaaac 541 atttcggaga ttattaaacg gatacttgac aatgaaatca ccgaagattc tcctggaatt 601 gtgtcttttg acagctactg gacgtttatt aaggataatt tttcatatag aacggatgcc 661 aatattaaag aggttgtaga aaaaagcgga atgttggagg atattattaa ccgttcattt 721 ccgaaacgac tttataaacc tttggcattg cagataatat atgctttaag cgtacataga 781 ttaaccaccg gtgatattag tattcgtgcg ggacttacgg cagaaaattt gagagatgac 841 ctctgcctgt atttaaaagg tatgcccgac caaagttcag atactttgca atctttaatt 901 caaacagtat tgaaagatat catgaccact gtcagcggac agtttattga atataatgcc 961 gataatgggc aatattatct tgatttgaaa aaagacatcg actatgacga aaaaatcacg 1021 caaagagcag catttatgga cgacgacagt ttgaataact atttttatga tgtcgtttat 1081 tattgcttgg aatgggatca gaaagaatat gttgataatt tcaaaattta cgaacacagg 1141 ttaaactgga tgtcccacaa cattttccgt tcaggatacc tgttttttgg tacgcctgaa 1201 tctcggccta ctgctcagcc gccggaggat tattatatat actttattcc tccctatggc 1261 aatgagagtt atacagacaa taaaaaagag gatgaagtct ttttcctgtt taagcccaat 1321 gaagaattta agaatacctt gaagttatat ggagctgctc aaatattgaa aggtttggca 1381 gaagtaaaaa ataagcctgc ttatcaaagt aaagctgaag tttacaagaa agaactgacg 1441 aaatacctta gtgaaaataa gaatacttgc tttgaggttg tttataaggg tgaaaagaag 1501 caactattgg aagtgatggg gaaactgtat aagagcacaa atccgtttaa agaaacaatt 1561 gatctggttg cttctatctg tttggatgaa tacttcgcga aaaagtatcc agaaatgcct 1621 aaattcaaga ttcaaattac cagccgaaac cgggtggaaa ttattcgggc aggtattgac 1681 aggtttgcag ggagaaaaag tcaacaggcc aatgctttgc tggaaagttt tgggttgctt 1741 gacggagata agattaccgt gcaaaattcc aagtatgcac aatattttat caaggaatta 1801 gaaaaaattc cagcgaatga agttatcaat tttagtgata tttatactga agttccaaat 1861 aaggatgaat attatataga caaacaattt ggaatctcct atgccctttt gcccattgtt 1921 ctgctggcat tagtacatac aggacatgca gttattacct taaggaatgg tactaccttg 1981 actgcttctg atttggaaat actgcccaag atacaggcaa ccgacatata tgagttcaag 2041 tatatttcca aaccgaaaga tatgcgattg gtggagctgg ttaaacttta tgaattattg 2101 gagttacctg ctggtttaat taacaatcct gcccagcgag aagcagggct tggaagacta 2161 ttggcaaaag cacaagaaac ggcgaatata gcggttaggg ctaacagtaa attaaatgga 2221 gattttgaac tttggggcga accgcttatt gccgaacata ttgcttcgga ttataaagcg 2281 gctgcaaaaa gagtgctgga tatgttagga aatttccaaa gcagattcaa tacagtggcc 2341 aaactcaata attttaatta tacaatggaa cagattgagc agcttggcaa agatattacg 2401 gcgtcaaaaa ctgtgttgga atacgaaaaa ttcagaaacg agtgccttgc taatgttagt 2461 tacatgatga atctggaacg tatggaactc ggaaatactt taagagcggc aattgagaca 2521 gcaaaagaga gttttcgaaa aatacgggat aatatacctg aggatatgag tggtgaagct 2581 gcggcagctg atgtaaatga gcttcttaca aaagttaaaa atcaatatat tgatatttac 2641 ttttcggaac atcagaaaag acggttgggg gtatccgatg gccgacgtaa aggagaactg 2701 gtaagctcgg taaaactggc taatttaaaa cgtttgagag agataaacag tattttttca 2761 gcccacaaac ttgacaacat tgaaaaagag ctggccgggt taaaagtctg ttatgagttg 2821 accccggaga tgcttaaaac cagccatttc tgccctaaat gccattttct catgaatgaa 2881 gaagacattc cggtgaaagg aagacttgat gagattgagg aacggattga taatttattg 2941 gatgaatgga ccaataccct gtataatact gtaaccgatc cgacccttat cgaacagaaa 3001 caatatctaa gtccacagca atgtcaggta attgatgagt ttattaatac gaaacgtttg 3061 ccggagaagg ctgaccaatt ctttattact gctattaagg accttttgca agggtttgaa 3121 cctgttgcca ttgcagccga tgaattaatc gacagactca gtgcgcttgg gccttgtgat 3181 atcgatacat ttcagcataa attgaaagaa cttgtggatg attatatcaa aggtaaagat 3241 aaagagaagc tgcggattat tataaaaaga taaggagaga ccggtatgaa gaaattaaca 3301 aaagaagata ttgacaaagt acgtcatata gagggttttc ctatagccaa tgacgaagac 3361 attatagctt tgtccaatcc accatattat acagcatgcc ctaatccttt tattgaggat 3421 tttataaaag agcatggcaa accttatgat gaagcgactg atgattatca tagagagcct 3481 tttgctgccg acgtgagcga aggaaagaat gacccgattt ataatgccca tagttatcat 3541 acaaaagtgc ctcataaagc tattatgaga tatattcttc attataccga gccgggggat 3601 attgtatttg acggcttttg tggtacgggg atgacaggag ttgcagcaca aatgtgcgga 3661 aatcctgatc cggaattaaa ggcaagaatt gaagctgaaa tgccttatgt caagtggggg 3721 gcacgtaaag ctattctaaa tgacctttct cctgctgcga cttttattgc ttataactat 3781 aatacacctg ttgatgttgc agaatttgaa aaagaagcaa aacgtattct tgaggaatgt 3841 gagaaagaat acggctggat gtatgaaacg cagcatacga ttaacggtga aatacagtat 3901 ggaatagacg gaaagccgat aatggggcgt atcaattaca cagtttggtc tgatgttttt 3961 atatgtccta cctgttccaa tgaaatagtg ttttgggacg cagctgttga caaggagaaa 4021 ggcaaagtca atgatacttt ttattgtcct cactgtaaca gtcaattgac taaacgtagt 4081 tgtgaaagag ctcaggaaac acatttcgat gcacggttga atgaatttgt taccatggcc 4141 aaacaggtgc cggttttaat taattattcc gttggaaaaa aacggtttga aaaaacgcca 4201 gacgaatatg atttggcgtt gattgaaaaa atcgacaata tggatatacc atactggtat 4261 ccgacggata ggatgtgtga aggcagcgaa agtcgtcgaa acgatcgata tggtataact 4321 catgtgcatc agttttatac gaaaaggaac ttgtatttaa atgcatggtt aagaaacaaa 4381 ataataaagg tgaaggacaa atgcattagt gatattttat tgtttggttt taacaatgtt 4441 cagcaaaggc attgtaaact gaatgcaatg agatttaatg tatcttttcc ttcaaatatc 4501 actagtggca ctttgtattt gccatcaatg atacgggaaa acaatattat agaccaattg 4561 agcaataagt attttaaacg tatagttaag gcctttaaag ataatacttc aaagtattca 4621 atagtgtcta caaatagtac aacatctaat ataataaata gtaataattc tatcgattac 4681 atttttactg atcttccatt tggtagtaat ttgaactatt ctgaactgaa ttttttatgg 4741 gaagcatggc tgaaagtttt tactaaccaa gaaccagaag cgattataaa tgctgttcag 4801 gggaaagggc tacttgaata tcaatcatta atgacacgat gctttgagga atgttatcga 4861 gtgctaaaac caggtcgctg gatgacggtg gtatttcata attcacaaaa ttctgtttgg 4921 aatgctatcc aagaatcctt aatgcgagca ggttttgtta tagcagatgt tcgcacatta 4981 gacaagcagc aaggtagctt caagcaggta acgacaacat ctgcagtaaa acaagacctt 5041 gtaatttcag catataaacc aaaagaaagt tttaagcggg agtttatttc ccacgctggg 5101 agtgaagaaa ccgcatggag ttttatacag caacatcttg agaaattgcc agtagttgtc 5161 gtaaagaacg gaaaaattga attgatagaa gagcggaagg cttacttgct ttatgaccgc 5221 atggtggcat accatattat gaatggaata cctgttccat tagatgcaac ggacttttat 5281 aaaggtttgg acgaaaggtt cttaaaacgt gatgggatgt actttctccc tgatcaggtt 5341 aacgaatatg atactgcccg tattgtaaac gacgtagagc caattcaaat ggaattgctt 5401 gttaccaatg aaaaatcagc tattgcctgg ctttataagc agcttgaaac accgcaaaca 5461 tatgcagaac tacagccaaa atttatgcag gaaataagag cttgggataa gtttgagaaa 5521 agaccggagc tttcagaatt gcttgaggaa aattttctgc aaaacgaaga gggtaagtgg 5581 tatattccgg atgttacaaa ggcttctgat gtggctaagc ttcgtgaaaa aaaattactc 5641 aaggaatttg aaggttacct ggctacaaaa ggaaagctta agttattccg tactgaagca 5701 atcagggtag ggtttgcaaa actctgggca gataagaatt ataagttaat tgtcgaaaca 5761 gcggagcgcc tacctgaaag tgttatccta gaagacgata agttgcttat gtattatgat 5821 ttaagcttgg gaaggatttg aggttaggaa tatgcttcaa attggtgact atgtttttga 5881 caaaacaaaa aatgaacgtg tgcagatatt ggaaatcagc gaagtatggg gctttgtatc 5941 atataaagta tttaatacct ctaccggaaa ggtttataag ttatctgctg acgatatttg 6001 tgccgaaata cctgaaaaac attataatga gagctatctt cggtatgttg ccttgctttc 6061 aaaaatcaaa aataagattt cccaaggcat cttatcaaaa ctatcgtgtg gcatcattcc 6121 attgccgcat cagcttcatg ttttgaatag agctttgtca aacaataatg tgagatacat 6181 attggctgat gaagtaggac ttggaaagac cattgaagcc gggctcatta ttaaggaatt 6241 aaaggccaga ggacttatca ggcggatatt aattgtttgt cccactggtc tagtaacgca 6301 atgggatatg gaaatgaagg agaagtttaa cgaaaagttc catgttatat tgccggaaaa 6361 ttatgacgct attcgtcaaa taacaggaaa tgaggatgtt tacgggcagt ttgatcaggt 6421 tatatcaccc atggattcta tcaagccgtt ggaaagacgg gcaggctgga cggaagaaaa 6481 gattgctaaa tacaatgagg aacggattta ttccattatt aacagcggat gggatttgat 6541 tgcgattgac gaagctcaca gggttgccgg cagttcagga gaagtagcac gatacaaact 6601 tggtaaatta ctggcagctg ctagtccgta cctgttatta cttactgcta cgcctcataa 6661 tggaaaaacc gagccatttt tgcgattaat acgaatgatt gatgaaaagg cttttcccaa 6721 tgccgatgct gttgtaaaag agcaagtagc tccttatgtt ataagaacag aaaaacgtga 6781 agcaatagat cataatggca acaaactttt taaaaaccga attataaaag ttattgaaat 6841 gcactgggat gaacggcatt ccatgcaacg caagttgtat gaaatggtat cagattatgt 6901 tgctaaaaat tacaacaaag ccatgcgaaa ccgtggaaaa aatatgtggt ttgtattcct 6961 gcttattatg atgcagcgta tggttacaag cagtacaagt gctgtcaggg aaagtatgga 7021 acgtcgtgtg agagttttgg aagaacaagc atttaaatat cagtcaatgt ctgaagagga 7081 atttgcggaa atggaattgg aggaaaacat ggaagaagca attgctgcca tttctttagg 7141 catcgaagaa gaaataactc agcttaacga tattattgca gttgccaagc aggcggaatt 7201 tcaatatctt gatgtcaaag ttgagcctct ttttgaaatt attgatgatt tatttgctga 7261 ggaccggcaa agaaaaatca ttatttttac ggaatttgta gcgactcaaa gctatcttgt 7321 aaaactgtta aaagaccggg gatattcaac gtccatacta aatggcagta tgagtataga 7381 ggaacgaaat gcagtgttgc atgagtttaa aacacaaaca gatattctta tctccaccga 7441 cgctggtggt gaaggtttga acttgcaatt ttccaactgc attattaatt atgacttgcc 7501 ttggaatccg atgaaaatag agcagcgtat tggacgcgtt gaccgtatcg gacagcaaag 7561 agatgtagtg gtttataatt ttatattggc agatactgtt gaaaaccgtg taaaaaccgt 7621 tttagaagaa aagctatccg taatactgag agagatcgga attgacaagt attcagacat 7681 attggacagc gaaactgctg agcttaactt tacggatgct tatatgcaat ccattcgtaa 7741 tcctaacgat attgaattta atattcgacg gattgaggag gatttaaaaa cgcaggttaa 7801 aaacacgatg caaataagag agcttataaa agaagaaaaa gatcttactt caatgatagg 7861 agcaggctct acttttgact ttgaacatgc attacgtcag atggttactt attatgaaaa 7921 ttataagggc aatccatttt tacccattga gaatttcagc attaatgatc ctattatttt 7981 tgaacattta aataaagaaa tcgaacaaga ctggagaatg cctctgttaa gcgtttcaat 8041 taaggatttt ccaaatgaaa aaggctattt tatgctgtgg aagatatcac ttatttctga 8101 cagcagagaa caaaaggtta tcccgatttt tatcaattgt gactttatcc tgcgccctat 8161 ggcaggcaaa aagatatggg aggcaattct tgacaaagac agaattatta ctgttcggaa 8221 aggagaagag attgatacag aaactaaaaa taaactttac aaagtgtcac aggaatttgc 8281 ttacgatact tttttaacaa tgaaagcgga attagaaaaa agaaatgaag aaacatacag 8341 aaaatatcta tatgctttga acctacgcat cgaagccgca cagcggatag gaatcgaaaa 8401 tatcagaaag cataaactga tgactttaaa ccgggagaaa gcagagatag aagccaatta 8461 tcaggcgggc aaaaaaattt gtcctgactt taagccaata ttgatagcgt atatggagtg 8521 aaattatgat tgaaaaacga gtagcagagc ttttttcaat tgaatatgaa aaacggttgc 8581 tgatatttga taccgacagg ttttgtgatg cttttgatta tatcggcttt cttatttcgc 8641 gagactttga agtaatacgg tatgaagata ttgaagcatt tcggctcaga tatgaactgg 8701 acataaggaa ttctgaacat aaatatgcgg ttgtcgtttt ttctgatata tacgtgccgt 8761 atgatataag gaagcagttt tttgaggttc atatttcttt taaaaacatt tttccgaaac 8821 ttcatgagga tacggtgcag cggtatgtga aagatattga cctgattagc tttgcctacg 8881 aacaacttta tttttcctgt gacactaggg aaaaaactga agaatttatt tcaaatacgg 8941 ttttttcaaa agagaatgta aaaaactatt gtgagttaat gacgaaaaaa cttctacctt 9001 ccggagataa atctggaatt actgcaaagg aatggattga aattgctcgt aaaaaggcat 9061 taattgatta ctatgctgca agggcaaata tttctgttga taccagcttt gttgacgtgt 9121 attttgaaaa atttatattc aacggttacc aaaagctttc aggtgaaaca aagaaagatg 9181 cgccggctat attgcctaag gtaattgatt ttatagcaca tggtaaaact gctcttgttg 9241 tcgtcgatgg aatgtcgctg tttgattttg aagttatctc acggtatttt gaagggattg 9301 aatatgaata ttattgtact tttgccttaa taccgacgac aacggcaatt tccaggcaaa 9361 gtttacttac tggaaagtat cctcgtgagt tgaaacatcc ttttacttta agtgatgagg 9421 aaaaaggctt tatagaaact gctcagaatg caggatatac gaaacaacaa attttatatg 9481 caaaaggctt caatcctccc gtcaaccatt ttaccaagtt tatggctgtt attatcaatg 9541 acatagatga cttggtacat ggccagaagc aaggccgtgt aggaatgtat aatgatattt 9601 ctttatgggc caaaagtggt aaattacaaa tgttgattaa agatttgtat gcacagggtt 9661 ttgatgttta tataacttca gaccatggta acactccatg cattggagca ggaactattc 9721 gtggtgttgg cgttgaagtt gaaaccaaat ccaagaggat gtttgtattg aaagattttg 9781 cagaattaag aaacttcttt ggagataaag ttgtggctta tccgggatat tacttggata 9841 atgactataa atactacgtt tgcaaatcag gtgtttcttt tgataatatg aatgaggaag 9901 taatgacaca cgggggcatc tcaattgacg aggtaattgt accattcatt aaagtaagga 9961 cggtaattta gatggcaaag atgattggac tatcccgttc cattagattg gaatggctta 10021 ataaaactgc agaacttgta ttggaaggca aggactatac gcaaattaaa gatgagttaa 10081 acgaatactt gtcttttgaa attaaaagtc ctactaacat cagaaaaacg agagaaattc 10141 ttacgaatat atgggtgaag attcctgatg cactttcaac tttaaaacgg caagctttag 10201 aagcttataa ggatgacaag tcgaataaac tagcattgca ttggagcatg atgttggttg 10261 cttaccctgt attctgtgat gtatgtgctt taataggcaa acttactagc atccaggata 10321 catttacgca tcctggctta aagaaaagct gtttgaaata tggggggaac gtgctactct 10381 gttccattcc atcgataaga tattacaaac cttgaaacaa attggagcta tagaaaatga 10441 gaaggttggt gtatatcgaa taaaaaagta cccggttacc gatgtaaaaa ccatacaggt 10501 gttgttattg gccattcttc acttaaggga aagagcctac tatgaaatag cagagctatc 10561 ttcggtaccc caggtctttc cttttgaatt caatgtttca tatgaatggc tgcatgactc 10621 agacttattt accttaagta actttggcgg taaagttgtg ttaacattgg attaaggtaa 10681 atcgaaatta gccgggattt gaagaaggtg ggcggctata tcgcggcaga acgggaatgt 10741 ttactgtgga ggactagaaa aacacacaac agaaatataa tattgatgca aacggcgact 10801 tcatagcagc agtctatggc ttagaggaac tgccgcttaa gaagctggaa cttgttgacg 10861 gcgaattgga tttaaaaaac tgttttccag gaaaatatat tctgaaaagt gtttatctgg 10921 atgataataa tatactgcaa atggcagcca ctcattttaa agtggggaga caatcacgct 10981 gcatagctgc aagggaatga tggaaaaact tggggcactg agtgcactac gtaggggttt 11041 acagtgttag tggcctctta acataattat tttctagatg aaggagcaaa ggtcctatat 11101 ctcttactat tacaaaaaaa gaaccattta tgaataacat cactaatttc accatggttt 11161 tgatatttac tgttttttag aacattattc ttcaaatagt tgaactgagg ttctattctt 11221 attgagccat ggagcatttg taggtgtaaa ataaaattct atattgttct tagcagccta 11281 gtttgcaacg ttttctgtct tatgcggacc atagttatca catacgatga acagggttat 11341 tttgggatat tgtacttgga cgtagttgtt tcaaaaattg acgaacttca atagagccaa 11401 attcatctac acagattact cgtgcatgct ctttatagtc ggtattgtag agttcccgga 11461 tgtgtttttt taatctgaaa atcaggatca tttgactctt tccacgtctt ggtcctctgt 11521 agagaaattc cagcggcatc aaggattctc ttgactgaca tgtagctaat ctcctcaaat 11581 attttctgtt caatggctgc tgtcttaagc cgatgcagag tccaggagtt aaacggatat 11641 cctaaagccc tatgagaaac tttggtaagt tcaattaatt gagttttctg attatcagtc 11701 ctagttgtag atcttccagt gtgcttttta ggatagatac attgtatacc ttcatcgtta 11761 aatgcattta taatgacagc aatattacgg ttgagagtaa tgataaattt cagaaagcct 11821 tttagaattc attccctcac ttgaagccag gatgactttt gcataacgta tggttttact 11881 ggaagttgaa gttttaatag ctttccttaa ctcattgttc tctccagcag ttagttttct 11941 tacgaataat tttttacttg ctccatagtt cattttgact attctctcta tgtttatata 12001 atagaggagt ggcaacttaa ttactagatg taaattctgt taactggcac tagggatggt 12061 ttaccggtaa attctcattc taatcgtata gcccccaaag aattaatagt tgagtacttt 12121 gttgccgtga aggaaaattc tgcatactca ctccaggaaa tatagtagga tattcgaaaa 12181 ctatatttga acaaataaca taattttttg tatttaatgt ataagtcctt cggagcttat 12241 ttatatatgt aatgacaaag ctgaacaata ttcgctcatt cgacttttga agaaattaca 12301 gactgcacgg taataccagg acttgacaaa ctcaacatct tatccattca tatttttgat 12361 cattctcaaa atattatcca tcgtaaaatt caaattctcc atactctttg aacggcttat 12421 ctcaaaatct tccggtaatc tgttaattgt gaataccgaa gtaactccaa aattatatat 12481 ttcatctata tccaggtcgg caccgcctgc taccactata accggcacat tggcaacaga 12541 tgcccttttt gctactccca ttactacttt acctctcagg ctttggctat caagctttcc 12601 ttcgccggta aatatcatat ctgcatcatg tatcagagaa tcaaatctta ctgtatccaa 12661 cacagtctca attcccattt gcagcgtgga atcaaaaaaa gccatcattc cggcacccat 12721 ggcaccggcg gctccggttc cgggtatatc tgccaaatcc ttgttcaaat ccttcttaat 12781 aacctcagac aggtgataaa ttcctctgtc cagatgcatt accatatccc ggtccgctcc 12841 cttttgcggc gcaaaaacat aagtagcgcc tttaggcccg tacatcggat tatcaatatc 12901 acacatcgtg actatttcaa taccctttaa aatttctgct tttcctgaca tgtcaatact 12961 gtcaatttca tgcagtgttc ctccggtggg aataaactca ttcccattcc tgtttataaa 13021 ttttattcct actgccgcag cagcaccaca tccgccgtcg tttgtgcagc ttcctcccag 13081 acccacaatt atctttttta cgcctctgcc ggcagcatcc ataatcaact gtccaactcc 13141 ataggtagtg gttttagaag gattcttcct gttttcaacc aacggcaagc ctgcacaggc 13201 agccatctca attacagcgg tttttccctg gtcaataagc ccatagaatg cttccatatc 13261 ttcaaagtat ggatttttta ctttcaccct gattttttct ccgccaacag ctctcaaaaa 13321 acaatctaca cttccctctc cgccgtcggc caccggaatt gaaattactt cacaacaggg 13381 aaaatattct tttacctttt tctccattat ttcgcatact tttgaagaac tcattgtacc 13441 tttaaaggaa tcaggcacca acactacttt cttcattcat aatctccctt taatatatgg 13501 aattatgctt agctgtaatt gacatttaca tgaattagtt cacaaagaaa catattgcat 13561 gtacacatca gtcattatat cactatttta tatgcaaagt aaatgcaacc attttgggac 13621 tgtcctctat tgactataac cataatgccg cctgctgtgt cataaagttt cagcaaataa 13681 caaaagcgca gttaaaacgt ttttgaaatg cttctcttca attaaatcac ctcctatttg 13741 actttctgtt aataataacc tataataagg caaaatgtta catgcttatc agaagtttta 13801 ccaaaagcag ttcattgatg ttcaaagagt aaaaatgttt acatggtaaa gtggggtggc 13861 ggggaatgga gtttactctt aacgagtcgc ttttatatta tcgtaatggg aaacttgatg 13921 gatggattca gaagttttgc gttcggaaga gggagatatg ccaaatccga attttgcttt 13981 agctgatggt ttgttgttag aggaaagaaa atatttttgc cctgtgaaca ttccactttg 14041 tgagattaaa acggtgcgta ccgaaaaaga tatttttgat gaaaatgaat taaagtattt 14101 taattataaa gtagaaaaga ttatatctaa actgcaggat tggaacatac cgccgcttat 14161 cgcccaattt gatggaattg attttgtgtt gaccgacgga aatcaccgat acagtgcact 14221 gaaaagactg gggaaaacca gctattatac tattgtatgg tgtagcagaa aatttgcaga 14281 tttagcaagg aaaataatga ctgaaaaagg atggtttaaa gacaaacaaa tatgagtcac 14341 aacgcattga aagggaatgt ctccatggaa atccggtact taaagccaga atggatgcga 14401 ttttaaggtg tgacggtttc gacggcaatg ttaacaggat taaatgcggg aaactggaat 14461 tgaacaaaga aacgaagaca gttttttaga aagcaaaatg ctggatttaa ctgcgaagga 14521 gtatgagctg ctggaacttt ttgttgattc catgagttgt tcagagatga acccctgatt 14581 ttccgactgt aaatactgga agttatagga agtaaaagca tgaacagcct taaccccagg 14641 aatagtttta agctctgtcg ataaggaagc taataagacg ctggattcac aatttataaa 14701 agatttcgaa cggcaaagga acagcctgct tacaattata ctgctgtcgg cactttcatt 14761 gttcatatcg gcagtgctga taatcattcc gaagaaaacc cttcgctggc aagtacctgt 14821 aacgtccgtg ctgtccttcg ccgttcttat ggtcagtata aaaattatga gctgtaatat 14881 caaaagttag ctgaaaaaga tgtttcatac catatgaaag aattgagatg cgtacctaat 14941 gagagattta tgcggtacta cagccccgaa acatcaattc cgacaatttt ccatgtaccg 15001 tttaatgagt ctgtcagctt catggaaact gttacattga ttaaagagct gctgctgtcc 15061 aggcgaactg ttgcatgagc ttcgactttg ccgctgtcca tgttatcaac cggatatgat 15121 atattgagaa cagatgcatc attgctcttt ttcctgatct ctttcaggtg aaatccatct 15181 gccatgtaat attggttcaa ttcctcggtt cggccggtaa agtacatggt cagcgcatcc 15241 tcaatcacta agtccatatt gatatctttg tatcggaaat ttttcagttc ccattttccc 15301 tcaccaagat aggcaatatc tgcatttatt ctgtgccctg taaattctcc cgaaaaaaag 15361 gtatcagaat atccaaggag atctgcattc agttcaatcc ggtcttcaac gaaatggatt 15421 tgaatctgca taccggcatg aaatttatag ttgacactgc tgtttctgaa ttcattatcc 15481 ataggtttcg tcagaccgac atgtttgccg tcaagtaata gtttaatgct gtcttctgta 15541 tacactgtat caaatttggc ttcaagctga ggcagatatt cattctcaag caattggtac 15601 atataccatt ttccgtcgtt tgctttatcg accataaata atgtctttat tgaacagcct 15661 gtgccatgtt taacatagat gataattgca agttcgtttt cgccgtccct atcataatcc 15721 atctcattta caaggggctg gaacatgtag tgggaggtat atggtacttt tgctgagata 15781 tatcggttgt ccggggtttt tacgatcata ctttccgtat ttgaggtacc gtacaacaaa 15841 aagtgctgcg tttttccgat taaattgata ttttcggtca tattgccctc aaatacagga 15901 tgaaaactgc cccagtcact ggcataatcc ggtgcatcca gtatacgttt ctttaaattc 15961 ggatccggtt caaaagtagt tccgacgatt aatttttcat cccagaattc ctcttcttcc 16021 gtataactat tctgattttc ggttacggct tcattttcag ccttcgaatc atcggctgcg 16081 ttattgtctg atgctgattc tttcccagat gccggggttt tttctgtatc actgatatta 16141 ttttctcttt gagttccatt cagcttgttt tcgttgtatg tattttcagc atactttttt 16201 cccgctgtaa gaaacaatac tccgcaggcc agtattacgg caaccaatac aatattcatg 16261 atacggtgtg gctttttgga acagagtata tgcttaattc tgttttcagt attatttttt 16321 gcaaaaccta ttgctaatgg taacccattg gctttctttg aaaaatccag tatggtttgt 16381 gagtattgct ttttttcatt tagtcctttt cctcttaaaa cacgttcatc acaatacatt 16441 tctatatctt ttcccatcag ggagaatgca atccagacaa aaggattgaa ccagtgtaca 16501 gtcaaagcaa tggttgccag gcattttatc cacggatcaa aatgcctgat atgctccctt 16561 tcatgtgtaa gaatatcctc acgctggcgt ccttcaagcc cgaccggaat gtagatttta 16621 gaaggaatac cgggcataac aaatggaatg tcacaggctg aagtttccca tatgttatta 16681 tccactttaa tagccccttt tagcatgtgc ctcaatttta tatattgtat aaggaaataa 16741 acagtgaata ctatgattcc cgaaagccat acaaaggata aatattctgc caatctgtgc 16801 ttttctgtgg gaatggaact gtcattattt gaagatgtga tattattttc agtcaaattg 16861 tctttatcaa tcctgttttc ctgtatcttg cgtgcaaggc ttaaattact gttaccggtt 16921 gaattaactc cttctatttg tttatatgta tcagagttat tgtagtttat ttgattttgc 16981 cctaaacttt cggagctgtc atagacgcca tcattaaaat taaggattgc gacatttcgt 17041 attgtatgaa acggacctgt gaccagcgga gtaaacaaca gttctgcaag cagcagaatc 17101 caaagaacag taacgtatct ttttgaaaag tttttggtaa gctgccttat tattaatatt 17161 accaatataa aaattatacc ggtaaagctg ttttgcagga acagttcaaa taacttggtc 17221 atttattcat cctccttagc atcgtctatg agtttctgaa gatattcagc ttcttcccgt 17281 gtcagctttt tatcctgtaa aaacgctgag ataaatgcag gcagacttcc ctgaaatttt 17341 ttatccagaa agtcacggac ttcctgcttt tgaatactgt tacgcgaaac aagtgcctta 17401 actactgcat tctcattgga aagaatcttt tttttgcaca ggtttcggat tacagtaaat 17461 gttgtggatt ttttccaccc aagcttatca taacatatcc ttacgagttc cattgaattt 17521 atgggctcca catcccatac aatgcacata aaccgatatt cactgtcgtt taaataatat 17581 ttcataacat tcccctttct ttaacttagg tttataacta tcgacctctt aagtttatca 17641 ttataaacct gtcttgtcaa tagatttgtt tcatactgaa agaggaaaca tatcaactgt 17701 cccggtagtg ttagatgtga gctgacatat aagataacgg ctttttttta aaaatcacaa 17761 catacaatat ttcccttttt tattttgcac ctttttgttt gatagtagga tttatttgta 17821 ccttttttag cagtaatatt aaaacataag gaaataaaac aacaaaaaat aagtcttagg 17881 aggacgaagt gcatgaaaat taaaaaaagt tggttggcac ttatattagc agccctaatg 17941 gcaatttctg tgactgcatg ttcgggttca aagacagaaa cgactaaaca agacccaaca 18001 actaaaaatc aagaaacaaa caacaacaat aataataaca acaataataa cgaagagaat 18061 gtattagtag tatatacggc aagaagtgaa gaattaaata aagctgtgat ttcagagttt 18121 gaaaaagaaa ccggaatcaa agttgaattg gtaacagcag gtacaggaga attgcttaag 18181 cgtgtagagt cagaaaaaga caacccattg ggtgatattt tatgggcagc agaccgtacc 18241 atgcttgctg catctgagga tttgttcatg gaatatgtat ccaaggaaga cggaaatatg 18301 atggaaggat tccagaacac aaccggatat ttttcgccgg catttgcaga tccagcggta 18361 tttattgtca atactgactt aaaaggtgat ataaaaatcg aagggtttga agatttattg 18421 aatcctaaac tgaaaggaaa gattgctttt ggagatcctg tcaactccag ttcggcattc 18481 cagtctttag ttgcaatgct gtatgctatg ggcgaaaaca atgacccaat gtccgataaa 18541 gcatgggagt ttgtagatca attcttaaag aaccttgacg gcaaaatggc taacagctcc 18601 agtcaggtat ataaaggtgt ggcagaaggt gaatatattg taggacttac ctgggaagac 18661 ccggctgcta aatatgtaaa agagggagct aacgttgagg ttgtattccc taaagaagga 18721 accattttcc cgggtgaatc tgtgcagatt ataaagaatt gcaagcatcc ggaaaatgca 18781 aagaaatttg tagatttcat gctgtctgaa gaggttcaga acagagtggg ctccgaattg 18841 acagttcgtc ctctcagaaa aggtgcaaaa ttggcagatt atatgacccc tcagtccgaa 18901 attaagttat tcagtaacta tgatgaagga tgggttgctg caaacaaatt ggcaattaca 18961 aacaagttta gcgagcacct ggaatcatct atggactaat acccgttaaa taaaacatta 19021 gattaagatt actgaacagg gccgcttaag gcgacgttac gtcgggaaaa actcatggcg 19081 tgacaggcaa aagtggccct tagtatttta ctactgaata aaggagaggt caaataatga 19141 gtgtagctat cagtatagag aatgttgtaa agcgttttgg aaaagagaca gttataaacg 19201 gattatcatt ggaaataaaa ccgggagaat tttttacatt gcttggaccg tccggttgcg 19261 gaaagaccac gctgcttcgt atgataatcg gatttaattc cattgaaggc ggacagatta 19321 aaattgatgg gaaagtaata aataatattc ctaccaataa gagaaatatg ggtatggtat 19381 ttcaaaacta tgcgatattt ccacatatgt cggttaagga taatatagcc tttggattga 19441 aaaacaggaa agtacccaaa gctgagattg agaaaagagt agatgaaatc ttaaaaattg 19501 ttaagataga tcatttaaaa gaccgaatgc cgcacaaaat gtccggtgga caacaacagc 19561 gtattgccct ggccagagca attgttattc atcctgaggt tcttttgatg gatgagcctc 19621 tttccaattt ggacgcaaaa ctgcgtacag agatgcgaaa cgctataaaa cagattcagc 19681 agcaggtggg gattacaaca gtgtatgtaa cccacgacca ggaggaagcg ttggcggtat 19741 ctgacagaat tgcagttatg aatggcggag taattcagca gattgatacc cctaaaaata 19801 tttatcagcg tccggcgaac acatttgttt cgacgtttat tggactttcc aacataatgg 19861 atggaaagct tgagagcaat gaaaacggca aagctttaat aagaattggt gattataagt 19921 ttcaaatgaa taatattaaa aaggactgtg gctccaattg ccctgttaaa gtgtcggttc 19981 gacctgaaga gtttattatt aacaaagaaa ccgaagaagg cattccggtt acagtgaaaa 20041 gcagtgtttt tcttggagtt acaacccatt attttgttga aaccaaagag gggcaggaga 20101 tagaggtaat acaaagttca gatattggag aaataattcc aaacggtaag aaagttcatc 20161 ttaaagtaca ggtgcaaaaa ataaatgtgt tcagtgaaga tggcagcaga agctttatag 20221 atagggaggt ccgcccatga ataccgcaaa aaagaaattg aacatatggc tggtattggc 20281 attggcaata ctagctttgt ttcttatttt tgtagtgtat ccgataggtc ttattctata 20341 taaaagtatt ttgatggaag atggcacaat aagtttttct tactttacga aattcttctc 20401 caaaaagttt tattggagta cgctggttaa cagttttaag gttaccatag cttcaacttt 20461 ggtatcagct gttttgggac taattatggc ttatttgtta agaagcataa agattaaagg 20521 cagcaagtat ttaaacattc ttattgttat atcttatttg tcacctccgt ttataggagc 20581 ctatgcatgg gtacagcttc ttggaagaaa cggagtaata acaagaattt taaattctgt 20641 tttcaatgct aaactgggcg gtatttatgg atttgcaggt attgttcttg ttttctcatt 20701 gcagtctttc ccattggttt atatgtatgt ttcaggcgca ttgaaaaact tggataattc 20761 cttgaatgaa gcggcagaaa gccttggatg ttcaactgtt caaagggttt ggaaagttat 20821 tgtgccgttg ataactccaa cgttgctggc cagttcactg ttggttttca tgcgtgtctt 20881 ctcagacttt ggtacgccga tgcttatcgg tgagggttac aagacattcc cggtactatt 20941 gtatagccag tttatgggtg aggtaagtac cgacgcccac tatgcagcag ccctttgtgt 21001 tattgtaatt gtaattacat tggttttgtt tttcttgcag aagtacattg gaaatcgtct 21061 gacctactct atgtcagcgt taaaaccgat ggagccgcaa aaagtgaccg ggattcgcaa 21121 tgttcttgcc cacggctttg tatatttagt tgtattggct gcaattttac cgcagttaac 21181 agtaattacc acatccttcc tggaaacaag aggtgcttca tataccggtc aatttacttt 21241 gcaaaattat aaaaatatta taatgccgaa aaatatcagt acaataacca acacgtatct 21301 atttggtttg gctgcaataa tattggttgt aattctggga gtattgatat cttacttaac 21361 ggtaagaaag aggtctttct taacctccat actggataca ttgacaatgt tcccatatat 21421 tatacccggt tccgtattgg gtatttcatt cttgtatgcg tttaacaaaa agccgctgtt 21481 acttagcgga acagcaatca tagttattat ttcattgtgt atcaggcgta tgccttatac 21541 aatccgttcc agtacggcta taataggaca gataagtcca agtgttgaag aagctgcaat 21601 cagcctggga tctacagagg taaagacatt tgtaaagata actgtaccga tgatgatggc 21661 cggtgtatta tccggtgcaa ttatgagctg gattaccctg attagtgagc tgagttcctc 21721 cattattcta tatacaagta aaactcagac tttgactgtg gcaatttata cggaagtcat 21781 tcgcagtaac tttggaaatg cggctgccta ttcaacggta ttgacaatta ccagtgtttt 21841 atccttgctg ttgttcttta aggtatcggg aagtgaggat ataagtgtat agttaaacgg 21901 ctattgtcaa ataacaatat attatagcgg aaagctataa tatattgtta tttgcattat 21961 tgggacattt tgtaatattt atgaaatcag agaggatgga atatggcatc taatcggtat 22021 agaagctatg tacagagaac attttaccgt tatacctttt caataatact gtttctttgc 22081 atattggtaa ttttatttct gataattaat atcaaatggc ttaccacaag caaaagtcag 22141 aggaacaatg caaagattgc agaggttttg gaacaggaaa tagtaagtta caaagaaggg 22201 ttaaaagctc ttgctaacga ttaccgtata ataaacttgt gtaaacgaca aacaaaggaa 22261 cagactgcaa atgtaaatcg cctgctctat gatttctcaa attctcagga aattcgtgga 22321 gtatttactc ttgtagattt acaaggaaac ttaatttgtt caaatctgta taaagacaat 22381 cgcaatatat ttttgcaaag ttttctgtat aaaagtttag tttcaaaaat gttatcagat 22441 ccccagagaa cttttttggt tcccagtcgt ctgaattatt cctataatca gacgggagat 22501 ttgctgatag gatgtactgt gaaggatgga aatgaagctg taggcttttt gttttttgaa 22561 ttgcttgatg aggaaatata tgagactgta agcagatata atgtagatga tgtgatttta 22621 accgatcaat ttaacaattt aattttttct attggaagac aaagcgagga ctctatggga 22681 aagtatcccg ttggaagttc tcagtttgaa aaaaatcaag ttgatataat tgaattaaat 22741 gggaagcaat atctgataat aaagagcatt cttaacgacg gcaccttgta tctgtatact 22801 ttgacatcta taagtttcca gcaggatctt tttcgatatg cgattttgtt cgttgtgatt 22861 atgggaatat taatactgac acttctgaaa cctctgactt tgcttgttac agacaaaaat 22921 ttacatgcca tagaagagct tagaaaatct atattggaaa tgggaagagg gaatatggag 22981 tattcgttgc gtccgcatgt ttttgaggag tttcaggaat tgaatgatac tttccggcaa 23041 atggtgttgc agcgcgaaga gcttcaaaaa agaaacaatg agctgatgga gagaaaaaga 23101 ataatggaaa tcagacaact ggaagaaaaa attaatcctc attttttatt taatgttctg 23161 gaaactttac gttatgaggt tatgattgat ccggctaaag cttcagagat gataatggct 23221 ttcgcaaata taatgcgtta taacatatat tatcgagata ccattgtacc tcttaagacg 23281 gacatagaac atgtaaaaga ttatttaatg ttgcaaaaga tgcgttataa tcgtcgtttg 23341 acatatagta ttgatatacc tgaggaactt atggaatgta aagttcccaa attagtaatc 23401 caaccaattg tagagaatgc attaaaacat gggatgaaaa atgttgaaac tattaatgta 23461 aacattactg cctccgttga aaatgaaaat ttgaggctga gtgttgagga taatggttca 23521 gggattgaac ctgaaatact gaacgaatta attaaggatt tggaaagaga agatgtatat 23581 aaagaacaca taggaatgta taattcccac agagttatca gactgctata cggaccgccg 23641 tatggattaa aaatagaaag tacctatgga aaaggcacag tggtaaatat aattcttcca 23701 ataaacaggg gagatgataa tgaataaggt gttaattgta gaagatgaag acattatgcg 23761 aaaaggatta atgtttatgc caaaatggca tgaagtggat tgcattgtgg taggagaggc 23821 ggtaaatggc caggatggtt tggagaaaat tcaaaagtac cgtccggaca ttgtaattgc 23881 agacattaac atgccggtca tggacgggct tgaaatgctg gaaaaaagta tacgggaata 23941 tgggtatgat gctattattg tgtcaggcta tggggaattt gaatatgcaa gaagaggtat 24001 tagcctggga gttacggaat acctgttaaa gccaattgat tattctaagc tctatgaagc 24061 cattcgaaag attcaggcta agagaaatgc cgatacgaat ataaagaatg caattcgtca 24121 gatagatgct gaaaagaaaa agttaggaat cctggaatat aaggaaagga aaacagggaa 24181 ccgttatgta gattttatga ttcaaacaat tcatgacaat tatcatacac ggctggctct 24241 taccgatatt agtgagcaat gccgaatgtc ctgtacttat ctgaatgtaa aatttaaaaa 24301 tgagacggga tatacattta acgattatct gaatcggtat cgtatccaaa aggcggtaga 24361 tttgttaaga gaaaatcagt ataagatata tgaaattgca gaaatggttg gtttttccga 24421 ttataaatat tttattaagg tattcaaaaa atatatcggt tgttctccgg cacgtttcat 24481 aagcgaaaac acagattaga aggcagtcac ttttttacag gaggtagctg aaataatcag 24541 ctacctccta atcggttcct tgttataatg tacttttata atgtactttc tctttctcaa 24601 atactttcac tttctcaaag catttcccgg cactttggtt ccggcagtca gcgcaacttg 24661 ctttagctct tctcccgata acgccgtgct accttaacag aggaacgtga aactataaaa 24721 cagttcaata caaaccgtca tacgactggg atttcatgag tttcaccaga cggctggttc 24781 ccagacggtc agcaccgagc tctatatatt tcctggcatc attaaaattg gaaatgccac 24841 ccgctgcctt aattttgaca ttggggccaa catgttttgc aaacagctca atatcctcaa 24901 aggtggcgcc tgcagtggaa aatcccgtac tggttttgat atagtctgcc ccggatctgg 24961 ttaccaaatc gcacataaca atcttttctt cttcagtaag caggcatgtt tcaatgatga 25021 ctttcagaat acgttcaccg caggcttgct taatggcttt aatttcctta agtacatagt 25081 cgtattcttt gtttttcaag gcgcctatat tgatgaccat atcgatttca tctgcgccgt 25141 ttgctatggc gtcctgggtt tcaaaaactt tggcggcagt agtcatattg ccattgggaa 25201 agccgataac ggtacagata accatgcggt cgcctacata ctcttttgcg cgggccacat 25261 agcatggcgg aatgcatact gaagcggttt gatacttgat agcatcgtca caaagtgcct 25321 ggatttcggg ccaggtagca gtttgcaaca gtaatgtgtg atccacatgg gataatatgt 25381 cttgtgtatt cataagattg ccttcctttc taccgattaa tatattccga agtattgtat 25441 attctattgt tatttttcca aatcctttgg tccaaaaccc atggggagga tttgctccaa 25501 tgtgaaaatt tcataatgct gagggtcttt tgcaagtatt acttcgaaag tttttggatc 25561 gcaaaattcc atcatgactt ggcggcacac gccgcagggg gcacacaaag ccagagtgtc 25621 cgctccttcc ggaccaccaa caatggcaat ggcggaaaac tccctgacac cttcgctgac 25681 tgctttaaag aaagcagtac gttcagcgca gttgctgggt gtataggccg cattttctat 25741 gttgcagccg gtatacagcc tcccatcttt ggacagcagt gctgcaccta ccgcaaaatg 25801 cgaatagggg gaataggatt gtttacgtgc ttgtaaagca tgggaaatca actcagatcg 25861 tgtcataaat atgctccttt cttatataca aagggaaaaa ggatactccg ccggcagaaa 25921 cgcacggcgg aataccgact gccccattta cttctgtttt aaatacggtt tgccgctggc 25981 ggcaggtacg cgggatttac cgacaaacag taccagcgta atgattgtta caacgtaagg 26041 aatcatggaa atcaggttgg gcgatattac attgcctgaa cccaaaagaa cctttaagcc 26101 gttgcacaat ccgaacagca ggcaggcacc catggctccg tgaggggtga atttaccgaa 26161 gataacagcg gcgatggcga taaagccctg gccgacaata acttccggac ggaactggct 26221 gacagtgcac agggtaacat aagcaccacc aagacctgcg aaaaagccgg aagcaatcac 26281 ggcaatgtag cggatgcgga atacattgat accttgagtt tcacaagcct tgggatgctc 26341 acctacggca cgaagacgca tgccgaatct ggtcttgtag aagataaacc atacgatagc 26401 cactgccaca aaagccagat aagtagcaac gtaggtgtta agaacattat tccagaaact 26461 tcccacctcg aaaacaccgt tgaacagctt gggcagcttt tgagctgtgt ccagcggagg 26521 agtgtttgag gattgttcaa acagtgcttt gcatacgaag atagctacgc cgggtgccaa 26581 aaagtttatg gcagtaccgg aaatggtctg gtctgcgccg aaagaaacgc aggctatggc 26641 atgaatcagt ccgaagagag ctccaaccag tcctccgcat aaaaaggcca gccaggcatt 26701 gccggtgaaa tgagccactg ccgcgcctac aaaagcaccg atggtcatca taccttcaat 26761 accaatgtta acgacgccac tgcgttccga aaaagtggag cccaatgcag cataaagcaa 26821 aggaggtgta gctatcagtg tggcgttaat aaccaagccg agatttttaa tcagttcttc 26881 catttatttg tcctccttat tcttaagccg tcttgtaatt aaatagcgga atacatgtga 26941 tatggcgata aagagcacga tggtgcccat aatgatgtca acgacttctg tgggagcatc 27001 aattagattg agcttggagc cgccgtattt catggcaccg taaaacagcc ctgaaaaaat 27061 acaaccaata gggtgagagc ttgcgattaa cgcaacggtg attccctgga agccgaagcc 27121 ttcctgtccg gcaaactgac tgatgcgcat ggagttaccc atcagttgca cggcaccgcc 27181 caaagctgcc agagcacccg acaggctcat ggcaatatac atcgtcttgt tggaattaat 27241 accgccgtat ttggctgcgt gaggattgag accaacggcc tgtactttat agccaagagt 27301 ggttttcgtc aggataaacc aaataacaat tgccgcaata attgccagga aaataccgta 27361 gttggcttta ttactctgaa aaatattctg caacgattgg ggcagcagaa ttcttgcaga 27421 ttcgcgaata tccttggaag cctctccgcc gccaaccttg tgaatagctg cagtattgac 27481 tacataattt gaaaaataaa aggcgatcca gttgaacata atgaaggaca aaacttcatt 27541 gataccgaac cggacgcgca gcactgccac cagaaagctc cacagcatgc cggcggcaac 27601 agcggccagc atacatagca gcacgtgcaa cccgggagga gcgtccacca ggatgcctac 27661 gcacagagca gccagtgagc ctacaacaaa ctgcccttcg gcgccgatgt tgaaaacacc 27721 tattttgtaa gaaaatgcca cgcttaaccc cgtaaatatc agcggagttg catagatcac 27781 cgaccaaatg agatacttgg gacggctgaa cacgctgctg aacagctttg catatgcttc 27841 aatgggactg aagccggctg cccacaggaa aatgccgccg accagaaatc cgaagaaaat 27901 agcaataatg gtatataggg cattttgatg aattagtctt tgtgctttaa ttttcaaaat 27961 attctgagag ggcttgttat tctggttgtt tttgtgtttc atttttagtt cctcctgcca 28021 tcatcagtcc taggactttt tcatcggcct cgtggcctgg cacactgcct acgatattac 28081 cgctgtaaat gacttcaatc ctgtcggaaa ggctcatgat ttcatccagt tcaaaggaca 28141 ccagcaatac agctttattt ttattgcgct gctccacaat ataacggtga acaaactcga 28201 tggcgcctac gtccaaaccg cgagtcggat taacggcgat aagcaaatcc ttgtcattgg 28261 taacctcacg ggcaatgatt accttttgct ggttaccgcc ggacagcttg cctgcttctt 28321 tggtgccgcc gtcagcaccc cggacgtcaa atttttcgac aagctctgcc gcatgcttgt 28381 aaatcgcatc tttctttaaa ataccgcgtt tggagaaagg gggttgttca taattttgca 28441 gaaccagatt gtaagctaca gaataatcca gtatcagccc gtgcttttgc cggtcggccg 28501 gaatgctgga tacgccatta tcaaacagtg tacgtgcatc ggcgttgaac aaatctttgc 28561 cgcctattat gacttttccg gattcgcctt tccgcaaacc ggttaaaatc tccaccagct 28621 cggtctgacc attgccgtct acgccggcta aacccacgat ttcaccacgg cgcactttaa 28681 ggcttaaacc cttaagcact tccacgccgc ggtaatccct ggcgtgcagg tcctgtatgt 28741 caataatgac ttcacctggc tcaatgggct tcttgtccac cacaaattga acatcgcggc 28801 ctaccatcat ggaagccaga tcgtgttcac tgacagcttc tacatcgaca gtgccgatat 28861 atttgccctg tcggataatg gtacacctgt cagccgaagc cttgatttcc ttcagcttat 28921 gagtgattag caacacggtt ttgccgtcgg ctgtgaggtt gtggatgatg ttgatcagtt 28981 cctcgatttc ctgcggtgtc agcgaggcgg tgggctcgtc gagaataagg atattggcgc 29041 cccggtacag aactttaagg atttcaacac gctgctgcat tcctaccgaa atgtcttcga 29101 ttttggcatc gggatccaca tgcatgccat agcgctcgga cagttccaac actttccggc 29161 gtgccttttt gatgtccacc accatacctt tggtgggctc catgccgaga ataatgtttt 29221 cggtaacggt aaagggttcc accagcatga agtgctgatg caccatgccg atgccaagtt 29281 cgatggcatg gcgcggactc tcgatatgca caggagaacc gaatatggag atgctaccgg 29341 atgtcggttt atacagtccg tacaatatgt tcatcagcgt actttttccg gcgccgtttt 29401 cgccaagaat agcgtgaact tcgcctttgt aaacggttag gttgatgtga tcgtttgcca 29461 cgaagttacc gaactttttg acgatgtcag tcatttgaac ggcaactacg ttcggatcaa 29521 tatggcttgt tttttccaag tccgtttttc cctccttata tgttggcttg cgggaattgt 29581 gtagtgtatt tgcttgtaat ttaaatgata ataatatctt taaagccttt ggctgcaagc 29641 agcccggcgt aatattccat ttgattacgt gtcggaattt gcaaagtctc cttatattgc 29701 gggcgaaccc ccatcggacg ataggatata agcttatatc ggatggggcg aatgggtaag 29761 tagctactga gcatgtcgcc gatttgtgta atggtttgtt ctgcatcgaa aaggcctggt 29821 gaaactactg tacgaacctc aaacagctta ccctttgatg caagaaaacg tgcatttttc 29881 aatacaacct ggttgctcca tccggtcacc cgcttgtgtt cttcacagtc aaatgctttt 29941 atgtcaagca ttacgccgtc ggtaacggcc agcaaatcag gatagtgttc aaaatcgagg 30001 gttccattgg agtcaatcag ggtggacagg ccatgagcct gtgccagaat aaacagctct 30061 gtcagaaact ccgggtaaag tgtgcattct ccgccggaaa cggtgatacc gcggataaat 30121 gggatttgct tttccacctt tcgccaaacc tgttccggtg tcatatcaac ggttttgggg 30181 ctgctgtcat gagggcatgc cttgatgcag ctgtcacaat ggacgcattt ggcacagttg 30241 taacgaactt tttcatcttc gaagcttaat gcccctgtgg ggcatgagtt gacacatgcc 30301 ccacagtgca tacatttgca tcttgtttca ggattatggc aatacaaaca gttcatattg 30361 cagccctgta aaaagatagc ggtacggttg ccaggcccgt caacggtgct gaaaggtatg 30421 attttgttga cagtggccac cataatcagc gcacctttct atccaaaatc tttccattca 30481 tgacggcgcc cattcccaaa gcggtggtgt cctgcagcac attctgaccg cttttcagct 30541 tttcgatttc cgaccgtttg accaggtagc ccgtgatacg gataacatcg ctgttcttct 30601 catagaagga cagatagcgc aattccttgc ggaaggagcc tttgacgatg tccagcacgt 30661 attcgggatt ttggtgaaca gtaacatcaa tagggaaaat gtcgcccgtt ccggatggaa 30721 aatatttatg gaaatgattg acaaccatga ggtgatcaat catttcgtcg ggttcctctc 30781 ctatggggat acgggtaccc ggcgagatat tttgatcttc tgaaattcct acttgcgcat 30841 gaagcagaaa atgaccgccg gttatttcgc agtaggggtt atggtgtttc tcactgaatt 30901 catatatctg cttgatgatg gattcaccaa gctcggtagc gtactcatcg tggccaaagc 30961 ggccgggacg gccctctttt tccagcagga tatttacaca ttccgccaga cccaccaggc 31021 caaacatggc agtgaagcgt ttgcggctga taaagccttc cctggccagg aagttatttt 31081 caaagaagcc gctttcttcg acttcaaagc ggatacggga gtccatgtaa cgtgccatga 31141 tgtccataac atagggcagc tggttggtcc tgaaatcttc aattccgccc gcgcgttttg 31201 caatgttgcc caaaatcagg cggcaaaggg tgtatgatcc gccgcccagc ggcaatccgt 31261 tatagcagct ggcaatgaca taattctcac caagttcctg cgtaaacatg cggtggttgg 31321 caaagctggg cttggccgaa cgcagggctg tcttgacagc ctgaatggcg aagtcgtcat 31381 cggttacgcc ttcttcgtat tttaaggtca gattgggaac ggcctgcgta agctctgcct 31441 ccacctcaag cagcaagcgg ccggtccgtg tgggcttggg accgatattt gcatgggaga 31501 aggagtcaag aatagtacgg tccacgtgca ccaaaaagcc tcgcagaagt tttttggccg 31561 tagtgtcgtc aacgtcttgc ataaaaggtt ccagcagcgt atccaactgt cccagatata 31621 ccgggaagtt ggttacgctt ggaacatgct tgtagaaaat cagcagagaa ttaagcgctt 31681 catataagtc ggtcggtggc gcaagctgca gaaaccggct gccttccttc atgaatttgg 31741 catagtcggg aatgatatat cggggacgaa gcggagcgtg tccctcattc aggtcgcaga 31801 tgcattttct gtctgccggg acattcatca gctcgtccag cccctgcggc aaatccaata 31861 cttccagcag agaatcggca gtattggcca gtgaagcaac cttttgctcg tgagttagta 31921 tcgggctttt gatgatatcc agtattttct tgcgcgtttc attcacgcgc tccatggaaa 31981 tgtctctcaa ttgttcgcca cccttccttg gataatcaag gttattttgc tcaaatcgtt 32041 aaaattagtc gtctaattcg tatatgttgc cgtattttgc ttcaaactca gccttggtct 32101 tcggaacggt aattttaccg ttgatgatgt cctgcttagc ttggtttaca taatcgagaa 32161 cttcctttgg caggttggtg gtggtaggag cgatgtctac acctgcggac tttaagtcat 32221 acgtgatgat gccaggctta acattgcctt cctttacggc tttggcaata tcaaagcatg 32281 cattgtcaac gcgtttcata gcagaggtca gaatgttttc aggagcaagc ggggactggt 32341 cgctgtctac accgattgcc catttgcctg cgtctttaca gccttcgatt acgcctaagc 32401 ccgttccgcc agctgcgtgg aagattacat ccgcgccgtt ggtgatcatt gtggtagcag 32461 cggatttacc ggtttcggtg ctgctgaaag agttagcgtt gaactgcagg atagtagcat 32521 tggggttggc atctttcacg ccggcaagat acccgtaacc gaattcgttc atggtctggc 32581 tgaccatacc gacaacaaat cctactttgt ttgttttggt cattttaccg gcaacaaggc 32641 caaccaggta ggaagcctgg ctctgctcga acatcaggca ggtaacgttg ggcaaatcga 32701 tggaagcatc gtcaatgatg gcaaatttct gatttggatt ggcttcagct gcttttctgg 32761 tggcatcagc cagcatgtat cctacacaga tgatgaggtc ataaccttca tcgatgaaag 32821 cttcaatgtt gggagcatag tcggcatcgg ttgcagattc ggcatagcga acttctacac 32881 caagttcttt ttgagcgcgc tgcagacctt cccaggcaga ctggttgaat gagccgtcgt 32941 ttacaccgcc aacatcggta accataccaa tcttaatctt cttgccaccg gtattgttgc 33001 tgctgttgtt attactgctg ttattgctgt tgttgccgga attttttccg ccacatgcag 33061 tcagggaaaa gactattata acggataata gtaatgccag aaattttttc atgttcttat 33121 ctccttttca atatattttg tttaatttat ttttctcatt ttcaacatat ttaatgttga 33181 aaccaaatta tttgttagat aattccaagg gcgacttcaa tcatattttt gaaaccgagc 33241 tggcgttcct gagccgacag ttctgtacct ttgtagatgt ggtcggagat ggacaggata 33301 cacaaagcat tttttcctgc ctgggccgca ttcatgtata aagctgccgc ttccatttcg 33361 atacacaaca cgcccatgct tttccaggca tcgttagcgc ctttattggc gttgtaaaac 33421 acatccgtgg aaagaacatt gccgatggcg acgctgattc cttttttctg tgcttcctca 33481 atggcttttt gcatcagcgt gtagctggca ataggtgcaa acgttccggg gagctggtat 33541 tggttggcgt aattggagtc ggtgcaggct cccatggcga taacgagatc ttttagatcc 33601 agatcgtcgc ttaaggcacc ggccgagcct atgcggatga tattgtccac atcgtagaaa 33661 ttgaaaagct cgtatgaata aataccgata gagggaatac ccatcccgtg acccataaca 33721 gacaccggct ttccctgata ggtgccggta aaacctaaca tattgcgcac tgtattaaaa 33781 caagtgacat tttccagata ggtttcggca ataaattttg cacgaagtgg atcaccgggc 33841 atcaaaaccg tttttgcaat ttgtccttcc accgctgcgt tgtgcgcagt gggcactctg 33901 ctcatttttt cacctccttt cttttgattg agtttcatct tcacgaataa gttcacgaat 33961 ggcatcaacc gcagcggccg gtgccaattc ggtatcgtgc acctggggat tattttcctc 34021 cttctgagga aattattggc aaaagaacag atgtatttat ataagcttta ggacctgcaa 34081 taaagttttg catttttaca atcctgatat gaagctttaa ttaagtcctc cacgtgaatt 34141 aatttttcca cttgcttcat gttttcttct gctcataata ccggagcctt tctaaagtaa 34201 atgctctgat attatgataa cttatagtat gtgaatattg tacaggtaat ataatgtaat 34261 tacatttttg caaaaggcta aacaatatgc ttattgatac ttataaattg ttagtatata 34321 atgtttaaaa aaagaatgca aaaatataca atttgaggat gaatttatcg aaaaaatgga 34381 gaagaaaata acaagaatag aaaaagattt tgaagaagga aataaaacac ctgaagaatt 34441 actgaaagaa ttagatgata gttcagatat agactgataa acattaatcc gggaaactcg 34501 tagctatata gccaggaaag ggaatttttt ggttgaataa aaagattaca aaaaaccaat 34561 ttcaaatatc aggagtgaaa atgatgaatg atgggaaaga aaaaaagaat gaaagcaatg 34621 ctgagagcgg gagtgattac gaaagaatag atgatatgtt tttccgccag attaatgaga 34681 ggagaaagga agacccgttg ataggcgcca aactgggtgc taaagaaatt ttcaacactt 34741 tattgaatgc tgtcagggat tcaagaggtg tacatattga gactcttata tgcgcactgg 34801 gagcccttgc gggttattca tgccaggcga gcctgaggaa agaattcgtt gagatcagag 34861 gactgagtga agaacaggtg tttacggtca tacaggcgaa aaacggcaag aggtactttt 34921 ttggcgacct tataaacaag ccgctgtttg aaaatcaata ttctgtatgg tccctggctg 34981 ccggcatagt gcagcacatg ggtgtgaata ttgattttga catccttgag attttcaaat 35041 atgtctctgc cacggtcggt accgagaact acggcattcc aaggattcca gagggacacc 35101 ggacggcaga cgttccgatc aattttgtca aggctttttg gccgttgttc ctcccccgta 35161 ttgagaagta ttgcgcttcc ccgcgtgagt ggccggtttt atttggattg gcgatacagg 35221 atggactgct tcaggggaag gatgtcatag acccttcact ggcgcttaaa atagttatgg 35281 aaagtgccat tccgatggca aaggctgaga ttgtgtttga ttaggggtta ttcattctta 35341 ttttgccgcc ggatgtcccg gtggcttttg tttttggctc aaactctgat tttcaatttc 35401 agggtattag tatacagatt tttacactgc catgcttggg actatttatg ggatttgtta 35461 caggttctta tttaagtgca tttgaatagt gtattattga agtttttaag tttcttggtc 35521 ttacatttga gctggaagag gataaaatgt ctcagaatga atgctaaaaa taaacaaaag 35581 ctccgagggc atcgagcccc catcgctttt tgttcatttc agttcgtgaa atttcgctaa 35641 gtaaagcggt caacagaaac tgccgaccgc tccaatcaaa ttcgataatc atccttcagg 35701 gattccatta acccatactc cagcaaaatt tcctccaaac gttcctggga caggggtttg 35761 ggtattgtaa aataagtatt ctcatctatc gcttttgcca accgcctgta ttcgtcggcc 35821 tgctgcgaat ccggcgcata ctcgatgaca gtttttctgt tgatttcagc acgctgtacc 35881 acattgtccc tgggaacaaa ataaatcagt tgagttccca gttctgcaca aaaagcacgg 35941 agaaggtcga tttcccggtc gacattacgg ctgttgcata taatacctcc cagtctcaca 36001 ccaccctttt gtgcaaactt tgcaattccc tttgcaatat tgtttgcagc atacaatgcc 36061 atcatctcac cacttgccac aatataaatt tctttggctt ttccttcacg aatcggcatg 36121 gcaaatccgc cacaaacgac atctccaagt acgtcataaa atacatagtc cagatcatca 36181 tcataggcac ccagctgttc cagcaaacct atggaagtaa taattcccct tccggcacat 36241 ccaacaccgg gttccggccc tccggactcc acacatttta ttccgccgaa tccgatgcgc 36301 acaatatttt caagtttcac atcttccccg gtctcacgca gcgtatccag gacagttcgc 36361 tgtgcaaagg ttcccaataa aagtctggtg gaatcggcct tgggatcaca tcccaccacc 36421 atgatttttt taccgctttc cgcaagtcct gcggtaaggt tttgcgtggt ggtggatttt 36481 ccaataccgc cctttccata aatagcgatt tgtcttattt ctttactcat atctctctaa 36541 cctccgtaat ctatatggta tattccggct gtggcagcgc acttgccaga tgcagttttt 36601 ctaatatatt ccgtcgaagg gaaagaaatt tggttcctcc acgatgccga ggatgtggga 36661 gattaatctc catgatctca ctgatttttc cgggccgcgg agtcataacc acaatacggt 36721 cggaaagata gattgcttcg tccacatcgt gggttaccag aatcattgtc gttttatttt 36781 ctttatgaag ctcaagcaat ttatcctgaa tatcggaacg ggtaaaggaa tctaaggcac 36841 tcatgggttc atcaagaagc agtacctttg gattattgat caatgccctg gcaatagcaa 36901 ctctctgagc catacctccg cttaactgat gcgggtaaca tttttcaaac cccttaagtc 36961 caatcaggtc tatataatgg gcaatacggt gtttattctc cctataaaca tggcgtgcct 37021 taagtccggt tgcgatattt ttctcaacag tcagccattg aaaaagacct ccatgctgaa 37081 aaacgtagcc ccgctctgga tctggtccgg agatttgctc tccgttaaga atcagggttc 37141 ctgtttccgg cttgtcaaga cctgctataa gccgtaagag cgtcgtcttt ccgcaaccgg 37201 aggaacctat gatggaaagg aattctcccc ggcggacgga caaattgata tcccgaagta 37261 cctcaacatg gtttccggcg tcgtcataat aagtgtaatt tacattttct atatgtaaaa 37321 taatatcact gattaccgat aagtttttgc tcattcctta acccatcctt tctgccaccg 37381 gagcacattc gcctgtatta gccccagtat tttcataatt agactgaaca gcagggccat 37441 aacgagaatg gaggcaaata ccttatagta ggcagaccac accttgctta aatttatgta 37501 gtaacccaat cctcccggct ggcccatcat ctctgccatt accaaagttg taaaagcaaa 37561 accattggca ttggaaatac cggtaaaaat ctggggcatg gcctgaggca ctgcaacatg 37621 gaatattaaa aatggcgttt ttgcccccag ggtgcgagct acttcgaact gatactttgg 37681 ggtggattgt atgccctggg ctgtaagagc cgcaatggaa aaccatgcgc atattacaat 37741 aagaaaaaca gctgctgaaa acggagacgg gaaaagcgtc agtgcaaagg gcatccacgc 37801 tacggcagga atgacaccgg taatctttaa tattggatat acccaataat atacctttgg 37861 aaaccaaccg attaaaattc ccgtacccac cccaaacacc acacccagag taaatccggc 37921 caaaaaaagt ttaatggagt aaagggtatt ttgtaaaata aaatctcctt caatcaaaaa 37981 ggattcaaga atttttgccg gtcccgggaa aaacggctgc ggtaataaaa gaagctttgt 38041 tcctaatata tcccaagctg taatagccag acccatagcg aaacgaaagg gagcctgcct 38101 ggaaaatttt tctcttcgca caggatcaaa atatgaaaat attcccatac cggcataaat 38161 caaaataatt actaccagga ccaatcggta aagcaaatta aatgtgaagg gaattcctgc 38221 aacaaaataa gttttgattt ccacatttgc cacttgcttc accagaatat tggctgctat 38281 ggctacagca aaccctgcca gtgtcagtac aaaattagta ctccaatttt gggccgaaac 38341 cgtttttagt tttccatatt gttgctttac ttttaattcc gaggatgttg ggctttgtag 38401 ttttactaaa tcgtacatag cagaatacct cctgtggggt gtttattatt tccgcccggt 38461 tcctccggtt caccgggcgg aaacaatctt tggaaatatt ataaacccag gttgatgtcg 38521 acctcgacat aagcattctt tgtgaaagta tcaggatccg tctttaaata tccaatttgg 38581 ttcaattgtt cggcaaaata gtaaacattg tctcgaacct gtgttttatt tttttcccgt 38641 tcggcataag aagggtattg atagctcttg ataagcttaa tggctaattc tctgtcttca 38701 atctgcgcgt atttaccatt tattataatg tcgacggctt cttccgggtt ttccgaaatc 38761 cagttttggg ctgccctata tgcacgcagc aatgcggcaa cctgttctgg tttttcgtca 38821 agcagctttt ccgaagcata aaggaaacag cagtattttc cggcaaaagg ttcatccttg 38881 gaaatatcaa gaattacacg gtaatttccc gttttttcct gaacagagcc gaagggatcc 38941 cacagtgccg caacatcaac ctctcctttt ctcagggctt ccactgccag atttccgtcg 39001 gagaagggaa ggaacgtaac ttctccgtcc tcctgctttg cggaaattcc gtttttctcc 39061 agccacaccg atgctacctg atggggagtg ccgcctattt catcaacgct gatctttttt 39121 cccctaaggt cttgaactcc ttgaatcggt gaatccttcg gaacaatcag ttttatgcat 39181 ccatagtgga gaccgtccac cacctttacc ttcacattgt tttcaataga gggaaagaac 39241 tgaaagtccc cgttgacaat cgggatggta ccgttgttca aaccgatttt acgggtttcg 39301 gtatctgccg atataaggtt gacatcaaag ccctcttgct tgaaaaagcc cttttcatat 39361 gcaatataga taggtgcacc gcaaagtgaa ccgtctttac cgggaatatc aatttttccg 39421 tatttgtatt ctgctgaaga tgtccccgtt ttcccgttgt cctgggtacc tcccgtattc 39481 gtcctgccac atccggaaaa caagcctata aaaatggaaa acagagcgac tgcactgatc 39541 aattttataa aacctttcat gataaaacac acccctttac gaaattatat atatgccttt 39601 tcaaacgcct gttccaaatc agctattaaa tctgccggat cttccagtcc tgccgatatg 39661 cgaattaagt tttccggaat atcggcaaat tttttctcat caggctccag ttcactatgg 39721 gtggtttgcg gagaatttac aatcaggctg cgggcatccc caatattgac atgataatga 39781 aagagtttca ctgagttcaa gaaagtttcc ctttgagccg ttgtcccttt gaaaccgaat 39841 gacaggattc ctcccgctcc ttttgggaaa tccctttgtg ccagctcata ataggggcta 39901 tccttcaaac cggggtaacg aacccattcc accgacttgt gggattttag gtattccgcc 39961 aggatactgg cattacgcac ttgtttttca acgcgctcag acagggtttc caatccgatt 40021 aaaacaaggt aggcatcaaa aggcgataat gccgctccaa agtagttgag atagttaaag 40081 cgtatcctgc cggtaaacgg agcctccgga aatacttcaa gaaaactgcg gtagttatcg 40141 ttaatgtccc gcagggtata atacttttcc gaaaactgag ggaatttatc gctctgccag 40201 ttgaatttac cgctttccag caccagtccg gcaataacgt ttccgtgtcc cgtcaatcct 40261 ttggtcgcag agtagaccac aatgtcggcc ccatgggaaa tagggttata caagtacggc 40321 gttgcaactg tattgtctac aatcagaggt atgccatgtt catgggcgac tttcgcaatc 40381 gcatcaatgt ccaaaagagc ggcattggga ttgctgatgc tttccacata gattgctttg 40441 gtatcgggct taatttcttc cgaaagcttt tcaggatttt ctatattttt agcaaaatcg 40501 aaggttatac caaatttagg ataaactttt ttaaaactgt ccgcactgcc gccatagaga 40561 tagggagaag tcaaaatacg acctccgccc tctgcaacat tgagcagagt ataactgata 40621 gctgccatgc cggaagccag tgccactgca ccgctggctc cgtcaagggc cgctacccgt 40681 tgctccagta cagcaaccgt aggatttcca atgcgggtat aaaggtttcc caattcgcga 40741 agtccaaata aagcttttgc atgctctaca tcgcgaaagt caaaggaagt ggtctgataa 40801 atgggcggcg atacggcata gttatgctcc tttggatcat agcctgcccg cagtctttga 40861 gtatcaaacc gatatgcagt tttttctaat tcgtttgcca tgttaaatct cctcctataa 40921 ataaatttga aagtatacat cggggcattt ccgtcatgtc acagtcacta cacatatcaa 40981 accacctcct aaaggattga taaatataca gctttatttc atcaagttac acttgctgct 41041 gccaattttt tatttttttc aatcatgtaa acttctctct gttcatctgt tttcaatcat 41101 gtttactttc aacctgcaca atatataggg caatatcatt aacaaactct taagctttca 41161 attgcgcaac ttttagccat gggaaaaggt attttccaat tttacaggcc taatatataa 41221 acttgaggat atatccttac cgcctggaat tccggcagca tctgctctac aacgctggca 41281 atgccggaat acattgatat aggcctgggc ttctgacctc actttgctga tgagatcaca 41341 tcccggtgtg ctgcaccagc taagcttgtg ctggggaatc agcggaataa tgttatagat 41401 ttttgctccg tgctgtgcaa cagtctttgc cacttccacc acatgatccg cgttgatctc 41461 cgggattaac actgtattta cttttacggt tattcctgat tgggatactt tcttaattcc 41521 ggcaagttga ttttgaataa gaatttttgc ggcttcaatt cctgtatagc gcttaccatg 41581 atagacaata ccctcgcaaa tctgtgcctg tatttccggg tcaactgcat tgacggtaac 41641 agtcaggctg tcaatgccca catcaataat ctcatcagcg tattccggca gaagaaggcc 41701 gttggtgctc atgcatttta taatatgagg gaattcctgc ttgataaggc gaaaggtctg 41761 cagtgcataa ggtgttgcca gggtatcacc cggtccggcc actcccgcta cagtaatatc 41821 ggggcaaagt tccaccgctc ttctcactgc atctacagct tcctgtggtg tgattattcc 41881 gcttgcaacc ccgggacggt tatccgtatc gttgatgtca cgcttgcaaa aattgcaggc 41941 aatattgcac ccgtaagata ccggcaaatg aacacgaccc ttattgtttt tagctcccgc 42001 cgcaaaacag ggatgatttt ttttcagatc ttcatatgta aatgccataa aacttcctcc 42061 ttaaccgcct tcttcatgca agcggccacc gaccagttgg gcaaggatct cttccacttc 42121 accggttgct tcaaagactc ttttgccttt ggctatcata acagctgccg cagcctgacc 42181 tattttcaaa acaaatattg catcacagtc ctccaacact gaaagaagat ggtcaaatcc 42241 gccttcgcaa tgaccctgac atttggcggc cgtttttcgg gtctccacaa aacgcgcctc 42301 tttatccaca tcatatatct gccagtatct ggccgagcca aagtgttgat caataacagt 42361 gccgtcaata ctggcaaatc caatacggta actcatacgg tcgccctcct tatgcatagg 42421 ttgaaagaac cgtctggtag atgtcctcta taacccgaag ccctcctgta aatcctgcgt 42481 aattggttgt caagaccaac cggtagggag aaggtaaagc agctgaaagg aaatcatagc 42541 ctttttcttt tgccagttcc ttatcccatc ctgaaccgat gatgaggccc cttcctttat 42601 gatggattcc cctaagaatc tcctgcgcct ttcccgcatc gggctcaaaa taaagcggaa 42661 tttccttttt atcgctggtg cttttcaaat cggcgcgaat ggcttcatgg aatttttccg 42721 gtgtagcatc ggtaataaat tgttcctttg gtacaattcc cacctcgtgc agcaaaaact 42781 tagacagtgc gacgacatat cccgcgtcat gaaggatatg ggcatggttg ggaagaccgt 42841 agcgaaactc caaaaggaag gtggcaaggt tatcaatctc ctcatagtag gcatgggact 42901 cgtgacggat aaactcctgg gctgattctt tgtcaatatc tgctccttgt tcgatggcaa 42961 attccacaac ttgattaagg aacgcctcgg tttgattggc acctatggga atgtgatgaa 43021 accatgtata ttcctgcccg tatttggatt tgaggtgatc cgcaatgggt tttccgtacc 43081 atggggaaac taaaatattg aaaagtgctg taggtatgga ctgccactct tttacacctc 43141 ccgactgggg tccgaataaa acattggctt taagcccaat accggcaagc agacgcttgt 43201 attcggccag attacccttc caaaacggat cctgatacgg aatggaggct ataagattca 43261 ctgtgttttt ttgcgatttt ggcttattct catcttcaaa ccggcttaca tattgatcta 43321 taatggcatt aaccacaagg ctgtgagctt caaagttggt ggccttaaat cctgcagttt 43381 ccacggatac aatcggctta cccttttggg caaattcaga aacaaggctg tccacatcgt 43441 ctccgacaat accggcggtg cagccggtca gaaccacctg caaatccgta tccaatactt 43501 tgtaggtgtt ttctataata tccctcagcc ggttgattcc gccaaacaca acttcttttt 43561 ctgtaaagtt tgtgcaggga gatgtggaac cgccggcgta tcccgttgac cgttcaaaaa 43621 atccggcaat catctcgccg cagccgggac cggaatgaag aatcggcacg gcccgcggaa 43681 tagccaccac ggtttgcaaa gcaccgattg cacaggtaaa acgttcttgt tcaatcaatc 43741 cggatctact catttaccgg tacctccttt caggaaataa tacggcggct gctcaagcca 43801 ccatttggtg tatggattga tggcatgctt ttcgaggttt tttacaaatt catcgttttc 43861 aataacttct aaaatacgct caccgtaatt gaccagacct tcataaccca tggagtaatg 43921 ttcatcgcca attaaaagtg acggaatgcc cagttttgct ccccagagag tcatgccgcc 43981 atgccgggcc agcaatacat cgggacggag gcggtttaag gcattgacca gctcaaactc 44041 ctgcttgttg caaacattgt agttaaaaac atttccataa tcggctacgc gctgagccag 44101 ttggtcgttt tcctcacgtc cgctgtcata gatggggtcg tgatggaaaa tcgctgcacc 44161 gactgcttta atgccaagct ctcccagcac atccagcaac gcatggccat gggcagcacc 44221 tgctgttaca taagccgttt ttccggccaa tttttcccgt agagcttcaa ttttgggcag 44281 atactctttc tttttttccg caatgatttt ttcagcaatt tcttctttgc cgaggatctt 44341 tcccaacgcc ctgaaccatc tatccgtttg tgcaataccg tagggtgggg cggcaggaat 44401 ttcgggaaca ccaaaatcct gttccagcac tgctcccagg tagcttccca gcgtggagca 44461 agcctggacg gtggcagcgg cctcgctggc atattttaat ccgttcactg tagaaaaagg 44521 gattatgtaa ttgggttttg ctccaaaggg agcaaaccat tcgtaaaaca catcgctgcc 44581 ccagaaattg attacattga tcatgtcatc ccgccgcctc cggggttttt gaatcagctt 44641 gcgtgcaatg ccgtggtaag cagcgtcaaa acctgtggtc catactttgg aacgaaaacc 44701 ttcgcaaaag atggctacca ccggtattcc caactcttcc tcggcttcgt tgcaaacgct 44761 ttccacatca tcgccgataa ttccggcagc gcatgtggtc aatacaaaaa tagcgttggc 44821 atgcgttctc tcatatacct ctcgaatggt attggcaagc tttatatttc ctccgtaaac 44881 tgtatccttt tcctttagat tggtggaaaa gatacggcgt ggtgtgggac gttcaatacc 44941 gcgcaaagga taattcaccc gataggtaaa ggcaaattca tgcagacagg aagcacagcc 45001 caccggtcca tggctgatga ctgcagcgtc ctgaattaac acagtcatac aggccgcttt 45061 tgaggtagca cagcccaggc attggctaaa ggaacgttct ttatccttca gaccgaattc 45121 gcgggcttct accagttcct tagcatctcc ctgataaccc gttattgaat taatacgaat 45181 ttcccttatc tgtacttccg gaagggataa atttattttt gacatttgtc atcactccgt 45241 tcgctaaaga ttccaaactt ttttcactca ttcgatatgt acgccggtct aaaaggggaa 45301 ctgcccccag atgcttataa aaccttgagc cgcttttatt gtcctcaagt acataccagt 45361 caagacgttt cgcacccatt tgcaaagctt tctttgcaag ctgtttcata agtgctttac 45421 caataccctt acctcgatat tcttctttca caaacaggtc ttctaaaaag aggttttgcc 45481 gtccggagaa ggtggaatat acgggataaa acagtgcaaa ggctgcggga ttaccgtcaa 45541 tttcagctat taaaacattt gcctgtcttt tttgaaaaag ggattcccga agctctgctt 45601 cagtcgttgt aacctctttg cccatcccct caaattctgc aagttcttta ataaacgaaa 45661 gcaccaatgc actgtcagat atatccgctt ctctaatatg taagtccata aaaaccaccc 45721 cttttgtatt aaacatatat gattagtatg ttttaaaata ttacactttt ctatatacaa 45781 tgtcaagcat tttttattaa acttatatga atgctatgta ttatgggatt ttaattttcc 45841 gttgtccatt tgataaacat gttttccata gtgaatggta ctaagatcat gggtaaccaa 45901 cagaaccgcc gtaccttcat tggcgatatc ggaaaacagt tgcataactt cataagtagt 45961 ctgcgcatcc aaatcatttg taggttcatc ggccaaaaga agtttcggtt tattcataag 46021 tgccctggct atggtgaccc gcctaagttc acccccggac aaatgctgtg gataggcatt 46081 ggccaaatgt gcaatgccga cctgctccaa aagggatagg gctctcttat ttacatctcc 46141 ttgacgtttt tgtaaataat gcggcaaacg gacgttatcg aaaacggaca aattcgataa 46201 aatactgtgt ccttgcggta tatagcctat ataggagttg cgaaacgaag acaattccct 46261 atccttcagg gacatgatat cacagccgtc aatactgaca tgaccgccgg ttggagaaat 46321 cagtccgccg attagattca agagggtagt ctttccgctg ccggaacggc cgataataat 46381 ggcaaaatca cctgctttca ttttcaaatg aacgtccctg actgcgaaaa acggccggtt 46441 gctccggata tattccttac tgagattact tacttcaagc agcattctac tcaccctccc 46501 ttaatgtcag ataagtttgg gaacggctga ctttaacggc agaataggct gaagcaattg 46561 ggccaaggga aaaagccacg agtaatgttc ccagtaaaat agctataatc caaagaagag 46621 aaggctgtat gtaaggcaat cctatgctgt caccaatgaa aacgttaaag ggaaatacaa 46681 atattgccgc aagtatagtt cctatagcac cgcctgacac actgatatac agcgactccc 46741 aaatcaaaac ggcagcaagc tttttccttg tggcccccag tatcctcata atagcaaatt 46801 ccttttttcg ttcattggct gaggctgaaa ataccaccgt caaaattacc aaggttacgc 46861 ccaaaagcac caatgcaaat acattaaaaa aggtgataat attgccaagg ctctttgaaa 46921 tgccggtaat taaattttgt gtcctgacaa tttggacacc gtccgttttt cttcggatat 46981 tggttatgac ttgatctata ttgtaccctt cacgaacttt aatcagtacg gatgaaataa 47041 aggtatcagg atccgtatcc tccaaaaagt taaagccttt ttcttttgca ccggaatata 47101 ggtctttaag ggtttccata gtagcaaata cggattgatc caatcctgtc cccgttttgt 47161 caagctttgc cgccacggga tattctttat caaaaaattt aatgtgcttg ttatcctcaa 47221 tcataatatc acttccgaca ataacagcac cgttttcaag atttcccccc agagtttctt 47281 gaatccacgg ttgaattgaa aaatccgtag ccggatcaaa tcccacaatc tgcacaggaa 47341 gagaacagca tcctgtactt agtgaaatga ggtaaaattg tgtcgacagt ttggaaatac 47401 cctcaacttc ctgaagcttt tggacaatct ctttattaaa ataaaagtag gacggctccc 47461 cggttaaaag aatggattcc tgttgtttcc catgcccgag aggaaccaca atcaaatctg 47521 caccaagcct tgcttctaca ctgcgaagcc cgtttctaaa gctaaaggac aggacagttc 47581 ctccaaaaag tgcaaaagac aggattgcaa ccaccaatat taatgcaaag gtgcgaaagg 47641 acttttttct gagatttaga aaggagattc tattcgaagt taatgcatat gccatcataa 47701 atttcccctt tgctttcaaa tctccacaag taaaccgtgt ttataccggc aaaaactaca 47761 agagctatgc ctgttaagct taacacgggc agggttaatg cccggcaggt catgtgtact 47821 ttggagcaaa cacccgttat gctgttggga aacagaaagg ccaatatccc aatgggtatt 47881 gcggcaatat tcaatccaat tctgaatttc ctatgattta ttaacagcat caagacacct 47941 acagcaattg tcagaatacc cagcacaagt tctgcttttg ccgtggcctg gcatctcata 48001 gccatcatcg aagctttgca aaccggaaaa attgaataag gtccaagagt cagtaaaaca 48061 ccaaatataa gatagacaat aggggacaaa actttatttt tcatcattat tcacctcaca 48121 aaaacaggtt tttggataga tagcgttcac ccctgtcagg cagcactgta acaatggtgc 48181 cgcgttgaat ccgcatggca agcttgcgta ccgctgcaag atttgctccg gaggacgagc 48241 cggcaataat accttcattt cgcgccagaa gcctggtctc ggtaaaagct tcatcatcac 48301 tgacttttat aacctcgtcc acaagggaca tatccattgt ttccggtata aagtcgtttc 48361 caatgccttc tatgtcataa tcaccatgct ctcctcctcc cattgtggaa ccgatggggt 48421 cggcaagaat acctttgata tccggttttt gttcttttaa gtaacgcacg attcccgcat 48481 atgtaccacc gcttccggca ccggcgacaa aataatctat gtccgctccc aggtcctccc 48541 aaatttcagg accggttgtt tcgtaatgag ccaacggatt tgccggattt cggaattgct 48601 ccagtgaaac ggctttagga atggactgcc gcaattcttc cgcttttcgt tccgccccca 48661 acattccttc ttcacggggt gtgttaatta cttccgcacc gagggcgcgg agcagagcct 48721 gtttttcttg tgaaaatttg gttggtacca ccataattaa ccggtaaccc cggttaaggg 48781 cggcaaaagc aatgcccagt ccggtatttc ccgcagttcc ttccactata gtgctgccgg 48841 gaaccaaaac acctcttttt tccgcatctt caatcatata ttttccgatt cggtctttta 48901 cactgccact ggggttatac agttcaagct tggcatatac gcggacaccg tcaggaaaac 48961 cggaatggcg aagacgtaca agaggtgtgt ttcctataag ttgttgcata tcatcatata 49021 tcatagtact cgcgctcctt ttatagcaga aaataaatcg ttttttaaat catcataatt 49081 ttcaatacct accgacaagc ggatcaatgt atccgtgatg ccgatctttt cgcgtatttc 49141 ctttggaaca gatgcatggg tcatgcttga aggatggcag acaagacttt caacaccgcc 49201 caagctttcc gcaagggcaa tcaactccaa accttcaaaa aacctgttga tgtcataatt 49261 gttatgtaac tcaaaggaaa tcatggctcc gccgtttttt gcctgtctct tttgaatctc 49321 atatccttga gcggatttta agccgggata atagacgttt ttaactgccg gattactttt 49381 taaagcctct gctagttttt ctgcgttggc cacatgggct tccatgcgca ctgccaacgt 49441 cttgatactt cgaatgagca ggaaagaatc aaacggcccg gcaacggcac ccaccgcatt 49501 ttgtatgaaa tgcagctttt ctgccagttc accgtcttta acgatgacaa gtcctgcaat 49561 gacatcgcta tgtccgccaa gatatttggt tgccgaatgc acgacgatat ccgctccaag 49621 ctctaaaggc cgttgaagat aaggggtcat aaaggtgtta tccactacag tcagcgctcc 49681 tttggatctt gctatctcag ctgccgccgc gatatccgta actttgagca gcggattggc 49741 cggggattca agcaacaaag ctttaacatc cgaagtaaat gcactttcga gtgctgccaa 49801 atcagtggtg tccacaattt tatagtttaa gccatactgc ttgaagattt tatccagaat 49861 tcgaaaagtc cctccatata cattgtcgga aataatgacg ctgtctccgg attggaagag 49921 atgcagaact gcatcaatgg ctgccatacc ggaagaaaat gcaaatcccc gggacccacc 49981 ctccaactct gcaatcaaag cctccaaagc tgcccgagtg ggatttcccg ttcgggaata 50041 ttcccaattt gagcggggct tgcccaaacc gtcctgttca aaggtggagg tttgataaat 50101 aggggtattt accgaaccgg tatggaaatc tccataaatg ccaccatgga tgactgccga 50161 ttcaatatgt ttgtaatgtg ccaaatcaat cattcctttc aatgttagta atcaggatta 50221 gtaatctggg gatattaatt ccggatgctt cgcctgtttt tttcttccag aaaagttttt 50281 tccattgata ttctttaggt tcttaaaagt tgtggactac cagttacctc tatttataga 50341 aatttattat tcatatatgt tttatatgtt ttatcataaa ctctcaactt caatttgtca 50401 atatcaaatt tactatttat atatgtttta ttttttaaaa tgaggtatat taattaatga 50461 taaagtattg aaatattgac aatacgcctt tttcccttta tcattattac gtactattta 50521 tatatgaaat gagtgataag gatgagaata tcggcaaaag gacgatatgc cctggcagcg 50581 gttatcagta tggcacagca atataacaac ggagaatata ttactgtaat tagcatttct 50641 gaaaaactgg gaatatctaa aatctttttg gagcaggtat tctcctcgtt aaaaaaggca 50701 aaaatcgtta gttccaccaa aggtgctcag ggcgggtagc aattaacaag aacaccaagc 50761 caaataaccg tattggatgt attgctgtcc gtcgaagtat cgttatttga gcaaacacag 50821 gaaacagttt ccgataaagc ccccgatatt gaacaagccc tccggtcatc ggtttttgat 50881 gttttggata aaaacatcaa acaaactctc agtacaatta caattgcaga cctggttgca 50941 gaggcagaaa agcataagga ttataatgcc ttgatgttct acatttaata agataaattt 51001 cttggccaat tcaccaaaaa tttgtgaatt ggccaaattt attattgact ttttttgttt 51061 taattcatat aatttatata tgattagcat gttttaatct ggggtatttt gaaagaaagg 51121 atgcacagta tgaaaaacac aattcgcctt atgccaaata ataatatgaa ctgttgtatg 51181 agtatgtggg ctatctgtat gcctaaattt cctaccgggg gataaatcta cccttctgtg 51241 ctttccgcag tcgggattgg agttatcccg gctgctttta tgtatgcgcc cggcatgggc 51301 gatagcttgg cggtgaaagt cgctccatat cctgattatt ttggataggc agagaattta 51361 gatttagtgg tttcattaaa agacatcatt ttttaaactt gcaatgatgc ttatataatt 51421 tcagcggaaa ggagaagcac agaatgtcaa aactgacgct gtgcgaaatg ggtgttatgg 51481 atgattatat tcagatttcg ggcttacata aaaccttcca cacacgcagc ggcccgattc 51541 aagtacttaa gggaattgat ttaacggtgc ggaagggtga gatatttggg attataggat 51601 tcagcggcgc agggaaatcc acacttgccc gatgcatcaa ccggcttgaa acaccggatt 51661 caggcagtat caaagtggga ggtgttgaaa tactcaacct ttcaaaaaag cagctgctgc 51721 aagagagaaa aaagattggc atgatttttc aaacctttaa tttgtttgaa gccaaaaccg 51781 tttatcataa catttcctac ccgctggaaa taagcaaaat cccgaaaccg gaaattcgca 51841 agagagttct ggaaacagcc gaacttgtcg gtttgtccga taagctgaat gcttacccgg 51901 gaggattatc cggaggtcaa aagcaacgtg taggaattgc ccgggcattg gttagccgtc 51961 cgaatctttt gataagcgat gaagcaacct ctgcccttga tcctcagact actctgcaaa 52021 ttctggattt acttaaagaa attaatcgaa ctaccggtat taccatttta atgattaccc 52081 acgaactgga tgccattcga tatacctgtg atcggatggc tgttctggaa gacggtaaaa 52141 tcattgaagt gggaaccgtt cgggaaattt ttaacaaccc ccttagccgt actggagccc 52201 tgttcactaa ggtatttacc gaatttcagc ggataacgga atttgaaaac ggtagtggta 52261 tttaataatt tcaacgttat aaatcatcgt aaaggagtga tggtatgagt ttgctggata 52321 ccccaatttg ggaggtgata aaaggttctt ttgcaccgga tatatgggta aggctggttc 52381 ccgctgttgg agaaacacta tatatgacag tagtgtcttc tatcataatg ctggtgttcg 52441 gccttttgct cggcattctg cttaccgtaa ccaatccgga cggtttggtg cccatgaaaa 52501 ttttatatac cgggtcgggc tggctgatta acgcactgcg ttcccttccc caaatgatca 52561 tgatcattct gatgattccg gtggctcggc tttttttcgg aaaatcttac ggcaccaacg 52621 cttgcatcat atccatcgct gccagctgta tccccatgta tgcaagaatt gtcgaaaaca 52681 gtctgcttga gatttcaaaa ggaaagattg aggccgcaaa gtccatcggc agcactaatt 52741 ttcaaataat ttttcgcata ttaattcctg aaactttacc ttccttaatc cgtgggttta 52801 cagtggctgt cattgccgta atttccatga ccgcgcttgc gggtatgttt ggagccggag 52861 gcatcggaga tatagcagta aggtttggct accagcgttt tcagcatgat gttttgtttg 52921 catccgtcta tgttttgatt gcccttgtcc aactggttca gtggattgga aactttacat 52981 ccaagcaaat cctgaaaaaa agaaatttaa tttaattaga ttggaggaga ttgaaaatga 53041 aaaaacacaa tgtgatcctt attatcctta cattgatatt agcattgggc cttcttgccg 53101 gatgcagcaa agaaggggat tcgaaaaaat caaccgtttc ttcggatatc ccggcttctg 53161 acagcaatgc aaatccatca ccttctcaag aaacaataac aattaagggt atcgccgatt 53221 tggttcccca ttccgaactc attgaatacg tggctcccag gctgaaagag caaggtatta 53281 ttgtagagtt ggttgcaaca gctgcagata acactaccaa cgaaaaactt gcaaaaggag 53341 aaattgattt taactttttt cagcatgagc cctatcttaa ggagtggaac aaagtaaacg 53401 gatataacct tgtaaatgcg ggagatatcc atgtggaacc cattacagca tattccgaca 53461 aatacagttc taaagaagag ataccggata atgcagttgt agcaattccc aatgacggta 53521 ccaacgaata ccgggctttg cgcatccttg aagaaaacgg atttatcaag cttaatcccc 53581 aaactgcaaa ctctcttact gcttcggtct cagatatcgc agaatatctg cgtccgataa 53641 ggattgtcga gcttgactcg gcacagatca ttcccacaaa agacgactat gatttcttta 53701 tcaccaacac aaataaggcc ctggaagcaa aaattacttc agcaaggctc ttcagcgaag 53761 gaagcgatag tccttatgcc aatatcattg ccgttcggga agaagacttg aataatcctg 53821 ccattgtcgc tttggtgaaa gctctgcagt ctgaagatgt caggcagtac ataacggata 53881 cttataacgg tgcggtgatt cctgcaaaac tggacaatta accgctcatt tccgggaagt 53941 tacagaatat attcatataa taccgaaaaa ctgctcaatt taaaaatagt tttgaccttg 54001 aaaaacaaac agatataata ataaaagaaa aaagaatctc accaaaaagg tgaagtgagg 54061 ctttattctg tcgaaaataa ttaatgatgc ggttgaaaaa gcaagaaaga taaaaccgga 54121 tataccttta atcggtagtg atggtagacc catcagggat gaatttgagc ttataaaacg 54181 gatgtagatt aaacctgctg aaaaaaggtt ttaattgagg tgaaaaaatg atttataaat 54241 actattataa aacaccggac ggtttttccg acatgttaat gaccagtgac ggcgaatatc 54301 tcaccggctt gtggtttgat gggtcaagag gtgcttcaaa gcatatttct gattgtgagg 54361 aaaaactact tccggtgttt gaggatacta taaaatggct tgatatttat ttcagcggta 54421 aaagccctga tttcattcct aaatatagaa ttgccaacct tacggatttc cgccgggaag 54481 taattgatag aatgcttgag ataccttttg gcgagacaag aacctatggt gaaattgcca 54541 aagtaatagc aaaaaagcgc ggtacggcaa aaatgtcatc ccgtgctgtt ggcagagctg 54601 tagggtggaa tcctatttgc attattatac cttgccatag ggttgtaggg gctaacagtt 54661 cacttacagg ctatggcggg ggaataagca ataaggttgc tttactgaga catgaaaata 54721 acgatatgag caaatttact gtccctaaaa agtgattcct ttgactgtgg tcttgcaact 54781 gaggcaatgt ctattgctgc acttgcattg ggatatggag cgaaaattgg acataatgat 54841 gattccgttg atgccacaac aaatgcctcc gcaagaaatt caatggatga aaaagttaag 54901 tttattaagt gatggaagta aaagcgaagg aaaggatgta ttatgtgtat ataacaatat 54961 atcctttctt ttttgtgtat ttaacttatt aaataattaa agcgatactt taaaaatcta 55021 ttgaaaaaat ttattgagag aattttaaac ctatgataca ctgatttata atatcttgaa 55081 aagatgtata actccaagat atgtaaagag cctgaaattt agatgaatac tgttcaaatg 55141 gatgaacagc ccatcttgat aagacaaaaa agtatatggt gttttaaata ttttatgatg 55201 gttccacgga tgatgaaatc atcggtttta agaaccaact cagacgaatc atcaaaaatc 55261 ttaaaaatga aggagtataa gaataatgga aaaaatatct atcggtccgg agaataaatt 55321 atgtccgcaa acattgtttc tgtatggtac atataaagag gacggaacac cgaactttgg 55381 tttgttttgc tggtttagtt attgttggag tggcgaattg ggggttatgg cttgcattgc 55441 cggtgaaaaa ttaacgaaag atcgtatccg ggcaaacaaa gtgttttctg ccaaccttgt 55501 cagcgaatcc ttgctgcatc ttgcggatta tttgggcaac acggaaggat ataatagcgg 55561 gaaaatgaac attccaattg aagtcgaacg tggtgcggta ttgaatgttc cggtattaaa 55621 gaacagtccg tgggtatttg agcttgaagt tcagcaatcc gtactgctgc atgacgccga 55681 ggtttttctg tgtaaaattc gcaatacatt agtagccaaa gaacttaaag ataattcaat 55741 aagtgtagat gaacggttac gcatggctgc acctgtaatg tgggtcggag agggtcaata 55801 ttatacacta aattatacag ctttaggcaa aacaggggac tggaaagact tgggttagat 55861 ttctatgatg ttgacatccg aaagatcatc gacacttact atattctttg ggaccggtga 55921 ttattataat tatggaataa ttggtgttta ctatgcgttc ttaacttttg taattgtctt 55981 taccgcagtt ggaataatca caacgcttct taacttgcca taatattcct tgaacttgta 56041 aactatcagg tagtacaaca gattgaattg ttgatattaa taaataaaaa gaatattgta 56101 tgataatatg aaaaaggaat ttgagagcga aaagagtact ctttatgaca taaaagacga 56161 tgaagaaaga acaaagaaag caaatgaatt aaagaaaaaa agccttgaaa ttgaaaagct 56221 tgtttggaaa gtaaaaactc aagaagaatt tgcggaagaa ttaaagtgtg ctttaatttc 56281 tgctaagacg gctttaaggg atttgaaaaa agcatttccg gatggaaaaa ttgatcctga 56341 aacaaaacta tttatcgaaa aaagggagaa gaaaatagca agaatagaaa aagattttga 56401 agaaggaaat aaaacacctg aagaattact gaaagcttct ttcaaaaaac accaattcaa 56461 acagaaaagt ttttgtcgtc cgggtcagca ggtgcgttga aatcaaaatc cttaaagtag 56521 cagacgttct gtggtgtgtt tttggcaggc ggaaattcaa aacctttgta tttcaccacg 56581 ggatttcttt ctttgcgtaa attatcaagg aactcatcag gaaggttcaa tactgatttc 56641 accacttcac gtggagttat tgcgagccat tgagcaagtg atacatcagc aaaatgttcg 56701 ctgttaaaga cctcaagaaa ttacagaggt tcatcgccaa tgttctgcac ataatggaac 56761 ccgcctaccg ggacatagcc tacatctccc ggactatagt tgaaagtacg ggctttggaa 56821 tccggcataa attctgtcat tcttgccctg cccttataat atttgtccct aatataatat 56881 tggaattcat cctgattggt atgcgaatgt atcttcctca tagcacctgg ttctactgtt 56941 acgagagctg ctgctacagt tttgcaggca ggaaaattgc gactgtcaag aatttgaatg 57001 gttcttccgt cacctttgat tggcggtacc ttgcaaagct catgcttgta ttgtatgaaa 57061 gaggaacttt ccctgtagga gaatctacgg tctgggattc cagggttcct gggtcgccac 57121 tgtctgtaat atatacttct tttttaggaa tgtttttaaa ggtttcttca ggcactccaa 57181 agtttgccga cagaaggtcg atgggcatgt gggcaaacag ttctgaaata gaaaaggtgt 57241 tgtgctctga gtaatctcct ttatcaaaga acatcggatt ttctctatca cgattctttc 57301 ttttttaacg ctatttttct cttattggta tcaaattatt caaaggatca atatcaaaag 57361 ctaccttaag cctcttattc cataaccctg cggcggactt gaaacatgta agcaaaaaac 57421 tgttgtgcgt tgacctaaga attttattca agtctgtaaa ggagaaaagt gccggtgatt 57481 gccgataaag ctattaacac ccgtggaaaa gtacgagact tccaaaacag actatacctt 57541 gcagctaaag ctgaccgaaa gagataattc catgcgttgt ataacaagat ataccgaaag 57601 gatatcctgg aagaaacatg aaaacgggtg aaacagatct gagttaaatg aaaattaaaa 57661 tgaaaggtat actaaactgg aaaatgtatg gtgacgacat tgagttgatt tccggttgac 57721 tggactcgaa aaataggttc gatattttaa agtattggca atttggtcaa taatctgaga 57781 taataaataa aaaataagaa aggatgaaag ataaaattct catttattaa accggacgct 57841 tttctaataa acttgggagg aaaagttatg actatagaag aacagtttaa tttgattgca 57901 aaagagtatg attgtaatcg taggaagttt attccttgct ttgatgatta ttatgaaagc 57961 attaccaaac tgattatttc caatattgat acaccgagtc gtgtgttgga tctgggagcc 58021 ggaacaggat tacttacata ttattggtat aaagaatgcc cgtcagcgga atatgtatta 58081 gttgatattg ccgatgaaat gctggaaatc tcaagaaaaa gatttgcggg gattgacaga 58141 atacagcata aaatattaga ttattcaaag gaccttccgg agggaaattt tgatgctatt 58201 atatcagcat tatcaattca ccatctggag gatatgcaaa aagaagaatt gttcaggaac 58261 atttacaata agctgccgct aggtggagtg ttcgttaatt atgatcagtt ttgtgcagga 58321 acatctaata tgaataagtg gtttgattca tattgggaaa agcaattata taacagcgga 58381 ttgacggatc gggatatcga actgtggaaa gaacgcagaa aattagataa ggagtgctcg 58441 gttgaaacag agattgagat gttatataaa tgtaattttt cagaggtgaa atgtttgtat 58501 tcttatcata aattctctgt aattgctgct attaaataat tgttggagta tcaagattac 58561 ggttttccaa actcggcgaa gaattattaa tataagatac atgaatgttt caaataatgt 58621 aggcacaatt agtgccaaac agcttcacta agcaatttta attacccagg caatgagatt 58681 cggcagcgtc ttaacgacga atgaattgaa aaaaacacac agaacatata aaaaatggag 58741 gtacagaatg aaatatagca ctattcagta cagacaggtg aaagacggca tagggttaat 58801 taccttaaac cgccctgaga aacgaaatgc cataaacatt cagatgagaa ttgagatttc 58861 tgattgttta tgtgaattgg agcagtcatc agatataaac gttgtaatat ttaccggagc 58921 aggaagttca ttttcagccg ggttcgattt aaatgagttt aataatcctt ctatatttga 58981 tgcacttttt gaatcttcct caaaatatca caggtatatt tggaaatttt caaaaccaac 59041 gattgccgct ataaacggag cggcaatggg tggtggattt gatttggcaa ccctttgtga 59101 tatacggata tgttccgatt ctgcaacatt tgggcatccc gaagtaaaat ttggtgcacc 59161 tccgctttat actcctctaa gatggatagt taaagacggt atcgcgcggg aactctgcct 59221 gacaggtcgt aaaattgatg caaaagaggc attacgtatt ggattagtga gcgaaattac 59281 aaatagctct gacctgttac agcgtgcaat tgaaatcggt gaaaccattt tggaagctcc 59341 gtcagataca ataaaatata taaagtcgta ttttatcagt aatgctgaaa aaggatttga 59401 agaatctttc cttatcgagc atgataaggc gtttcaggat attttattgc caaaagctaa 59461 aagcgggttt ttcctgcaaa atggcaggaa atgagataat gaaatgtatt gaaacagcaa 59521 aatttttatt gacatttaca aaaagggtat aaatcatatt tacagtctac tttattttat 59581 tattatcagc gacattgatt ctattaagta atattatgaa gaataagatg taagctattg 59641 tcataataat atgacctaag cctgccatac cggaaatcga agaatctatc attgttgata 59701 tttcaagttt taatacctca atacatccac gtatagccat cattataaat gataataaaa 59761 gtccgatatt gtaagttata aagaatttgt taaaattctt gttcttactt aattcaaagg 59821 atttttccag taataataca attaagaaga aaattgcgcc taaaactaat atatgaggat 59881 gcacaccgct taagacagtt tttcctgtaa agccgtttat ttttgtgaat tccctgtaaa 59941 aagctccaaa aaacaatccc aacatactat aaaaaaaact taattttgca actttcttca 60001 tttaatactc ctccgttcat ttaaatttat ttagaaactt tccaacatgt tataaaagac 60061 ctgtaataaa tataccaccg tttagtacca ataaaaacaa aacacaaaaa taatgcgcaa 60121 ttcaactact aataattttt ttgttcccat tccaaataag taattttatc ggtataattt 60181 aattaacaca agtaagtaag ggatttactg aagagacggg atagattata cacttttcga 60241 ttctcgaaaa aaagcctgtg agagtgttct aagtgtgatg gaatagagtc agtgtctgct 60301 gacaaaacag cttggacatt tgcgttggtt ataaaatagg cgaatatata tagacaataa 60361 tttcaataaa aggagcgagc aataaatgga aaaagcaaag gtttattttt cggattttcg 60421 cacggtgcct ttcggagacg gactgcctac aaaacttaag aaactcataa aaaaagccgg 60481 tatcagtcag atagatatgg acggcaagtt tgtcgctatc aagatgcatt ttggtgagct 60541 gggaaatatc agctatcttc gtcccaatta tgccagggct gtggttgacg ttgtaaagga 60601 gctgggcggc aagccttttt tgaccgactg caatactatg tatcccggaa aacgaaaaaa 60661 tgcccttgag catttggagt gtgcatggga aaacggcttt acaccgctga cagtaggatg 60721 tcctattctg atcggggatg gactaaaggg taccgatgat atcgcagtac ctgtaaaggg 60781 aggacaatat gtaaaggaag ccagaatcgg gcgggccatt atggatgccg acgtgttcat 60841 cagtctgact catttcaagg ggcatgagat gactggtttc ggcggagcga ttaaaaacat 60901 aggcatgggc tgtggctccc gcgcagggaa aaaggaacag cacagtaatg gcaagccgca 60961 tatcgatcag catttgtgcc ggggctgccg cagttgtctg aaagagtgtg ccaacaacgc 61021 tttagtattt gacacagttc acaaaaagat gacggttgat aaggaaaatt gcgtgggctg 61081 tggtcgttgc cttggttcgt gtaattttga tgctatttca tttgaagacg atgctgccat 61141 cgagcagtta aactgtcgta tggcggaata cgccaaggca gtggtggacg gccgtccttg 61201 cttccatatt tccctggtgg tggatgtatc cccttactgc gactgtcatg gggaaaatga 61261 cgtgcctatt ttaccagatt tgggtatgtt tgcgtccttt gacccggtag cattggatca 61321 agcgtgtgta gacgcatgtc tgaaagctac accacttccg ggaagccgcc tgaccgacaa 61381 catgaataaa ccggactttg ttgaccatca tgaccacttc atcaacacca cgcccgaatc 61441 cgaatggcgt tcctgtttgg agcacgcgga gagaatcggt ttgggtacgc gggattatga 61501 gctgattgta gttaaataaa ttgatggccg aataaaaaat acttagtaaa ttatcctaga 61561 tgccttttta tattttcagg ggaaccgtcg gaaaccaaaa aatatataac acgataaatt 61621 gcggagcctt atacgcggaa ggcgttaaaa agccatatgg ttatactgat tgaggacgat 61681 tttatgttct ttgggaggca cgaagatcat tatgatttcc tgattgtcct cggtaaagcc 61741 gaaagagaaa agtttgaagc agtaaagcat gagttcccgc ttgagataca acagcttatg 61801 aacgtgaacg caccctgcac gatggtaaat ggctgttaat tcgagtagat gatttaaaaa 61861 ctctggaagc tgtcaaaaag ctgatactta ttaagaaaaa gccgaaccgc aagccatttc 61921 caaaagaaaa tgccgtgtat ggcgtatctt cctgggatat gcgatgcacc ggttgtgata 61981 ctaccggttg tcattgtcgt cgtgaaggaa atgagttgtg tgagccgtta aaatgtttac 62041 ataccgaaca gcttaaaact tgctttccga acagcttaaa acttgctttg attgcaaaaa 62101 gtacccatgt ggacaagcaa ccgttggata caagtacttg gaacgcagaa atatttccgc 62161 tcatgatgtt acatgggcga ttttgcctta tgttccatat taatatgaaa aataatacag 62221 ggcatacata atttgagttt ctaaaaaatg ctatttcgat gaatcttggt attcattatc 62281 ttttggcgaa agtacactga cgttatctga ccgaaagtta tcgacctatg tcaatgcttt 62341 gtcaaaagct gggtttatta tagaataaat gattgaggag tctgatgatg aaatcataca 62401 gagggataac agtgaatttg cccgaagggc tatgatgttt cctgtaacct ttgttataaa 62461 ggcaaggaag ctgtaataaa aatttaaccg gtacaatttc cctgaaatca ttttaacgcc 62521 ggagaaatac agctcttagc ggaatggatc agtctctgat gatgtgaaaa ttgctgtgta 62581 tcaatttgcg gtttcggatg atattcaaca gaattatcgt attatcaaaa ggcgatacct 62641 gaagcaggtc atcaagtagt tagtctgttg caaacaaaaa tttacaaaaa ctacctgttt 62701 gatatatgaa atatgaggaa atacgagata gagaaaaatg ggtattatca ggagcttatt 62761 aaaaatcata atgtggttct taatagcaga gtttggatgc aattttatta tgcaaacaat 62821 aagttattca tattattctt aagcataaac ggttataatg aaaatgtcat taataagata 62881 tgcttttatg agacacgccg taggaccatt taaaatattt agccatccag atattgggat 62941 gcacaaaagg aagtggaaat atgattgcat cacaatgcag gataacacta aacgcaaaga 63001 attaaagacg caaacttctt atttgaagct gtgggagaaa tagagccgaa agaaagcttg 63061 aacaacttta aaaaaagtat caaagatgcg ataccgaaaa ttgatgcgga gtatataatc 63121 atttataatc cggacaaatg gaaataccat gtgttttatt ttattgatga tttagaaaaa 63181 gtgaaaacag aaaaaggtgt gatttatacc atacttcata tatcacaata aaaattttct 63241 attgacaggg taagttgaga tgtattaaaa tataaagtaa aaaaatagta ataagttgta 63301 acaaagcgat gacgaagaga agtaacatga attatcgttt acagtgagcg gggaatagtg 63361 agaaccctgt aaagtgaatt catgtgaata acacttcatc agcttcaatc tgaaagtcat 63421 atgggatatg acgagtaggt gcgacgtagg ccgaacgtta aagcggcaaa cactgaggag 63481 tgactgtaca aaggggtata gtaattcagg tggtaccgcg gacaataatg ctgttcgccc 63541 tgaaatttct atttcgggcg agcagctttt ttatattttc ggctgttctc ccgacaaaat 63601 aaatttgagt aaagatgagg agggagattt tatggcggag atttatcgta ccaagacaat 63661 gaatcaaatc actgaagaag atattggcag cgtccttaaa attgccggtt gggtggagaa 63721 catccgggac cacggcggcg tgtcctttat tgaccttagg gacatgtatg gtgtcatgca 63781 ggtggtattc agaaatatcg agtttccaaa aggtatcaga aaagaagagt gcttatccat 63841 tgaaggtgtg attgaaaaac gggatgaaga aacctacaac cccaagattc ccacaggtac 63901 cattgagctt gtggcgcaaa aagtgacggt tttgggccgg gtctacaggg atctgccctt 63961 tgaagttgcc acttccaagg aaattcgtga ggaagtgcgc ctaaagtacc gctaccttga 64021 tctgagaaac cggaaggtaa aggataatat cctgttcaga tcccaggtca tcagcttttt 64081 aaggcagaag atgaccgaga tgggctttgt cgaaatccag acgccgattt tgtcggcatc 64141 ctctcccgaa ggagcacggg attatattgt tccatccaga aaacataaag gaaaattcta 64201 tgcactgccg caggccccac agatatataa gcagcttttg atggtctcgg gctttgacaa 64261 gtattttcag atcgccccat gcttccgtga cgaggatgcg cgggccgatc gttctccggg 64321 cgagttttat cagctcgact ttgaaatgag ctttgccacc caggaagacg ttttccgcgt 64381 gggtgaggag gtgctgacgg caacctttaa aaagttcgca cccgaagggt atgaaatcac 64441 cgaggcgccg ttcccagttt tcagctacaa gcaggccatg ctggaattcg gcaccgacaa 64501 gccggacctt agaaaccccc tgcgcatcat cgatgtgacc gatttcttcc agagatgcgc 64561 cttcaagcca ttccacaaca agacggtcag agccatcaag gttcatgccg atatgtccaa 64621 gggcttccat gaaaaactgc tggaatatgc actgtccatc ggcatgggcg ggcttggcta 64681 ccttgaggtt caggaggata tgacctataa aggccccatc gacaaataca tcccccagga 64741 actaaaaggg gagctggccc aaatttccgg ccttattccc ggcgatgtca tattcttcat 64801 tgccgacaag gaaaagcttg cctgcaaata cgcaggacta atccgcaatg agctgggcaa 64861 gcgccttgac atctgcgaga agaatgctta ccgcttctgt tatgtcaatg attttccaat 64921 gtatgaaatg gatgaagaga ccggtaaaat tgaatttacc cataacccct tctccatgcc 64981 gcagggtggg ctggaggcgc ttaataccaa gggtcctctg gatattctgg cttaccagta 65041 tgatattgtc tgcaacggtg ttgaactttc ctcgggtgct gtccggaacc atgacctgga 65101 tatcatggta aaggcctttg agattgcggg ttacgatgag gagactttga aaaagaagtt 65161 cggagcgctc tataatgcat ttcagtacgg agcgccgcct cacgctggca tggctccggg 65221 gattgaacgg atgattatgc ttcttaggaa tgaggaaaac atccgcgagg ttgtggcttt 65281 ccccatgaac agcaacgcac aggatctgtt gtgcggcgca cccggcgaag ttaccgaaca 65341 gcaactgcgt gaagtgcata ttaaaatcag gaattaagcg tgtttgaatt atccggacga 65401 acttgacggc aggctgctgt cagaaatgga gtgaggatta tgaaaatttc gaaaactgag 65461 gtagaaaagc ttgcaaaact tgcaaagctg agcttctcgg atgaggagct tgagcgattt 65521 acggctgaat ttgatgagat tatagcattt gcagatacca tcaaccaatc catcgaaggc 65581 gggaccgaac agataagaag cgtgggtgcc aggatggtct cttttgatga cctgcgccct 65641 gatgaagtgg tgccgtccct tcccaatgaa aaaatccttt ccaatgtgga agggtataac 65701 ggatttttcg gcttggaaag gagtaaaaaa tgagaacggg aatatctgaa ctggcaaaaa 65761 ggcttcaaag ccgcgaaatt tccgcgatgg agctgacaaa agcatatatc ggtgcaattg 65821 aaaaattgaa tccaaccatc aatgcctatg tgtatttgac ctttgatact gccatgaagg 65881 ctgcggaaaa ggccgatcaa aggcttaaag agggcggtgc gccgctgctc tgcgggatcc 65941 ccatggccct gaaggacaat atttgcactg acgggcttaa caccacatgc tgctccaaaa 66001 tcctgaaagg ctttaagcct tactatgacg ctaccgtctg ggagaagctg aaagcccatg 66061 gtgcagtgct tctgggcaag accaatatgg atgagtttgc catggggagc acttcggaaa 66121 ccagctgcta tggggcgccg ctgaacccca gaaacacgaa ttatgttacc ggaggttctt 66181 cgggcggttc ggctgcggct gtttgcgcca atcttgcggt atacagcctg ggctcggata 66241 cgggcggttc tatccgtcag ccggcctctt tctgtggagt ggtgggactt aaacctacct 66301 atggggcggt atcccgttat ggactcatcg cttacggcag ctctctggac cagatcggac 66361 ctatgacaaa cagcgtgaag gatgctgcca tcgttttcga tgctataaaa ggcggcgaca 66421 ggcgcgatca gaccagtgtg gattatgatt atggttccta tctggctgaa tgtctggacc 66481 gggatgtcaa gggaatgcgc attggtgtgg ccgaggaatt ctttgacggt atcaatccgg 66541 agattaaatc aaagattgag gaagccataa agctgtttga aagaaacggt gctgtgatag 66601 aaaatatcag gcttccggcc ttaaagcttg cgcttcctgt atattacatt atcgcctgtg 66661 ccgaagcatc ctccaacctg ggacgatatg acggtatccg ttatggttat cgcacatcct 66721 catacaccag tattgaggac atgattgtca aaacaaggag cgaaggcttt ggtgacgagg 66781 ttaaacgccg catcatgctg ggaacctatg tgctgtccag cggttattat gatgcttact 66841 acaagaaagc ctgcctgatt cgtgaagaga taaaccggga atttgatgcc gtatttgaaa 66901 aatgtgacgt gctcgttgct cctactgcac ccaatacagc atttccgctg aactacaagg 66961 gtgcaggccc ggttgagatg tacttgtcgg atatctgcac tgtacccgtc aatatcgcag 67021 gcgttccggc catctcggtt ccctgtgggg aggattccaa cgggcttcct gtcggcatgc 67081 agatcatcgg taagaaattt gatgaggcaa cggttcttca agcggctcat ttttatgaac 67141 aaagcgccgg agaagtgatt ggcgtatacg aaggaggtgc caggatatga attatgaaat 67201 tgtctgcgga attgaaaccc atattgaact ggcaaccaaa accaagattt tttgcggctg 67261 caccaccgaa ttcgggggag agcccaacac ccattgctgc cctgtttgca cgggtcagcc 67321 gggatccctt cccattctca accaaaaagt ggtggaatat gccattaaag ccggcctggc 67381 gctgaactgc aaaatcaata ccaagtccca tatggaccga aagaattatg tatatcccga 67441 tttgccgaaa gcctaccaga tttcgcaata tgatgagccc ctctgtgaaa agggctatat 67501 cgaactggac agcggcaagc gtatcggcat tacccgcatt catatcgagg aagatgccgg 67561 aaagctcgtc catgagaacg ggtataccta tattgactat aaccgcagcg gtgttccgct 67621 gattgaaata gtttccgagc ctgatatttc ttccgccgaa gaggcaaggg agtatgccga 67681 aaagctgcaa cttatcatgc gctatatcgg catatcggac tgcaagatgc aggaaggttc 67741 catgcgctgc gatgtcaatc tttcactgcg aaagcccggt gattcccgtt tcggcgtaag 67801 aaccgaaatc aagaatatca actccctgag tttcattcaa aaggccgtca tggccgaggc 67861 ggaaaggcag gccgatattc tggatgccgg tggaaccgtt gttcagcaga ctatgcgtta 67921 cgacgaggca accaatagcg tcagtcctat gcgtgacaag gaaaactccg atgattaccg 67981 ctatttccct gatcccgata ttctgaggtt cagtatcaat gatgagaagg tggaagaaat 68041 tcgggcgtcc ttgcctgagc tgccctttga caagctcaag cggtacgtga atgtcctggg 68101 tcttcctgag gcaacagcca gacagatttt caggtataga aaggtggctg aatttttcga 68161 aggcgcgctg gcggagggtg caagcgttaa aaatgcggcc aacctgattg tcggtaccat 68221 cttttccaat atggacaccg aggaggaaaa ggaattattt gacatcagga tttcctctgc 68281 ccagtttgcc gcgcttgtaa agcttgccga tgagaagaaa attaacatcg gagttgccca 68341 gagcactttg caaaaaatgc tggagagcgg caaaccggtg gaggagttta ttaagccgga 68401 agatcttgcg agtatttccg atgaggagct tgaaagctta tgtaaggaag ccatcgatgc 68461 caatcccaag gcggtggccg atgtcagaag cggtaaggac aaagccatca atgtgatgtt 68521 cggatacatt atgaaaaaaa ccggcgggaa ggcagatatc cgcaaggttg aagttttgtt 68581 gcgaaaattg attggacaat aaaatgcagg atgtgcatga tgacggcgtc aaagaaggtg 68641 gtgagggtga taaggataag aagatacatt cgatccaata ataagaaaga agcattagta 68701 taaagcctga ataagcaatg cttcggcctg ctggataaaa agagcaaaag ccccggattg 68761 ggaaatataa agctgcgatg ttattgaatt taatttaaaa atgaaatttt taattttaca 68821 tcttgcaaaa tgatgtggag tttgttaaaa taaatataac cggagttgtt agataggtta 68881 ggacagtaaa attggttcgg atgtaacaga ggccgttttt agtgacatta tcaaaaagat 68941 gatgtattgc atataaaatt taatagcgtt taacagaaac aaaggcgttt cacattgact 69001 gtggaacgcc ttttttgcgt attcgtattg ggatataacc ggtgatgaac cggatattat 69061 taaaaactgc tggatagttt aggctttaat aattttgaaa ggagaataga ttatgggaaa 69121 atgtattgat gagatcaact gcggtatgtt tgggtcagct gtgtttagtg atgctgtaat 69181 gcaggagcgt ctgccaaaac ctgtttataa gaaactgaag aaaacaatca aggaaggtct 69241 tccgcttgat ccggatatag ctgaggttgt ggcctgtgtg atgaaggatt gggcggttga 69301 aatgggtgca acccatttta cccactggtt ccaaccgttg accggcgtta ctgccgaaaa 69361 gcatgattcc ttcctgtcgc caacagggga cggcaaggcc atcatggaat tctccggcaa 69421 ggagcttatc aagggtgagc ctgatgcttc gtccttccca tccggcgggc ttcgtgcaac 69481 cttcgaggcc agaggctaca ccgcatggga ttgtacctcg cctgcatttg ttaaggataa 69541 aacgctgtat attcccacag ctttctgctc ctatacgggc gaagccctgg acctgaaaac 69601 accgctcttg cgttcaatgg aggctctatc caagcaagcg cttcgtattc tgaggctctt 69661 tggcgatact accacaaagc gggttgtaac aaccttggga cccgagcagg aatacttcct 69721 tgtggacaag gaaaagttca tgcaacgtaa ggacctgatc tacaccggaa ggaccctgtt 69781 tggtgcaaag ccgcccaagg gacaggagct tgaggatcac tattttggaa ttatcaagga 69841 gaaaatctcc cgcttcatgc atgatctgga tgccgagctc tggaagcttg gagtttccgc 69901 caaaaccaaa cacaacgagg ttgcgcccgc gcagcacgag ctggctccgg tgtttgccac 69961 gaccaatatt gcaaccgacc ataaccaact gaccatggaa atcatgaaaa aggtggctga 70021 caggcacggg cttgcatgcc tcttgcatga gaagccgttt gcaggcgtca atggttccgg 70081 taagcacaat aactggtcca tctcaaccga cgatggcagg aacttgctcg atcccggaac 70141 aacgccgtcg gaaaatgccc agttcctcat tttcctggtg gctgtcatca aggctgttga 70201 tgattatgcg gatctgttgc gcttctctgt tgccacagcc ggaaatgacc acagacttgg 70261 agccaacgag gcacctccgg caatcatgtc cattttcctt ggcgatgagc tgaccaatgt 70321 tattgaggaa atagagaccg gcgtagtcaa gaacaacgga accagcagaa ccctggaaat 70381 cggtgtatcc acactcccag ttcttccgaa ggataacacc gacagaaaca gaacctctcc 70441 ctttgcattt acgggcaata agtttgagtt caggtccgtg ggttcctcac agtccatcgc 70501 cacaccgaac tttattatca ataccattgt ggctgaaact ctgagccaga ttgccgatcg 70561 cctcgaaaag gctcaggatt tcaaagcaga agtgaatgct gtagtgaagg aaatcattaa 70621 gaaccataaa cgtattattt tcaatggcaa taactattcc gaggaatggg ttgctgaagc 70681 cgagagaaga ggtctgccga atttgaagac cactgtcgat gccattccgg tacttatcgc 70741 tgaaaagaac ataaaggtac ttgaaaagca tggagttttg aaccgcgcag aagtgctttc 70801 acgttatgaa atctgcctgg agaactatgt caagacaatc cgtatagagg ccctgaccat 70861 gattgaaatg gcaagcaggc agatcctccc cgcatcactg gcctatgtcg gaaaagttgc 70921 tgataccgtt gcttccctca aagcggcagg tgccgattcc tcctttgcca aggaagagct 70981 tgatgaactt gtatcactga catcaagcct gaaagccgcc atcgacaaac tgagtgcgaa 71041 gcttgaagag gtcgatgcgc atgaaggaga ttcgctggag catgcccgcg cttataagga 71101 tgtcatcatc ccgctgatga acgaattgcg cgcctttgct gacaagcttg aaaccatggt 71161 ggatgcaagc ttgtggccga tacccaccta tggcgatctc ctgtttagtg tcatctgata 71221 agaacttgag gcaaaggaac aggtaccttg ttccgcacac aatatagaga aaaccacctc 71281 aaaaatttgt aagatttttg gggtggcttt ttttatatta atactgaaag gtttgttcat 71341 aaaaaagttt ccctatagtt gattttatca ccttatatta accataaatc cattgaggta 71401 tgatttgttc agaggatata ataaaagtgg gtgatgaaga tgaaagaaat caatatagcc 71461 agaaccatcg ttaaaatgcg gcgtgagaaa ggactgacgc aggaagacat tgcaaattac 71521 attggcgtgt cgaaggcttc ggtttctaaa tgggaaaccg gtcagagtta tcctgacatt 71581 acttttctgc cgcagcttgc gacacttttt aatataagca ttgatgagct catgggttat 71641 gaacctcaaa tgagtaaaga ggatatccgt aaactgtacg tgaaattatc tgccgatttt 71701 gcttccaaac cttttgatga agtattgaat tcttgccgcg aaattgctaa aaagtatttc 71761 tcctgctttt acctgttatt ccacattgga ttgctgcttg taaacaacag cacggaatcg 71821 ggagacaagg aaaaaaccct ttctgtgctt tcggaagcca aagagctgtt tgttcgggta 71881 aaaacagaaa gtgatgatgc cgagcttgtg caactttcct tatgtatgga ggcatgctgc 71941 gcgttgatga tgggaaatcc gaacgaagta attgagcttt tggagggaac aagaaaaaaa 72001 atcatttcca gtgaaacgat tcttgcttcg gcctatcaaa tgattggtaa atcgaaagaa 72061 gccaaaatga cattacaagc tgctatatat cagcatatgt gtaatctctt tagtgcatta 72121 accgattatc ttttgctttg tacggacact cccgaacagt ttgataaaac gctgaagcgt 72181 gcaaatgaca ttgctgaagc ttttgacttg aaaaagcttc atccgtcgtt gctcatgaag 72241 ctctacatca ttgctgccca gggatacatg atgcttggga gtaaagaaaa gtctctggaa 72301 attcttgaaa aatacacgga acttgtcacc ggtgatattt acccattgca gctaaaagga 72361 gacgaatatt ttaatctgat agatcagtgg attgaagagc tggacttggg gaatgctctt 72421 ccaagagatg aaaaaattat acgcaagagc atggctgacg gagtcatcaa taatcctgcg 72481 tttacaatat tggctgatga aatccggttt aggagaattg cagaaaaact gaagaataac 72541 tgttatcaac aagacgcacc atgaaagaaa taaaaccaaa acattattaa aggaggaatg 72601 aagcatggat tcggctatgt tgaaagaata tttaccgttt cttattccgt tggtcatcgc 72661 acagtatgca cttgctatta ctgcacttgt acatgtgttg cgccatcccc gttaccgttt 72721 cggaaataaa gtgatgtggg ttttgatcgt cctgtttata cagtttatcg gtccggcctt 72781 atactttgct ttcggtagag gtgaggaata gatgggtgtc ctggaaatca gacagcttta 72841 taagagcttt gggcaccatg aggtgctgaa gggattggat atggatgtcc ccgagcattc 72901 catattcgga tttgtcgggc agaacggcgc cggcaaaacg acaacaatga aaattattct 72961 tgggctattg aagccggaca gcggttctgt aaccgtatgc ggtgaaaaag ttacgtatgg 73021 cgaatccaaa gccaaccgcc acatagggtt tcttccggat gttccggagt tttatggata 73081 catgaatcca atggaatatt tgaagctgtg cggtgagata gccggccttt cgaagaccca 73141 aattaagtca aggagcgagg agttactgga acttgtcgga ctgaaggacc aaaaaaagag 73201 aattagcggg ttttccagag gaatgaagca gcgccttggc attgcacagg ccttgctgaa 73261 tgagccaaag ctcctaatct gcgatgagcc tacatcagca cttgatccaa tcggcaggaa 73321 ggaaatactc gatattttgc ttgcggcaaa agggaagacg accatcgtat tttcgaccca 73381 tattctatcg gatgttgaaa ggatatgcga ccgtattgcg gtattgcatg acggaaagct 73441 tgcgctttgc ggtacacttt cggaaataaa ggagcgccat aggctccatg gttttatcct 73501 tgagttcgag aatgaagaag cagcttcctg tttcgaaaat acggaagagc tgaagcagcc 73561 gtcaatcagt ctgtcacggg atggaagcac ggtaaaggtg tttatgaaag atggcggtat 73621 ggacgggcat tttttgttgg gtgtgctatc gcaaaagcgt attgttccgt tgaaattcgc 73681 agtgatggaa ccgactttgg aaagtttgtt tatggaggtg gttcggtgaa aggttatttt 73741 gcatttttga aaaaagagtt ctttgaatac acaaaaacct ataaactatt cattatgcta 73801 atgattttta taatttttgg aatcacgaat ccccttatag caaaattgat gcctgaaatt 73861 gtcggaagcc ttgtaaccga cggcgtcgtc ataacattac cggagccgac ggcctatgat 73921 gcctgggcac agtttttcaa aaatgcgacc caaatgggac ttttcgtaat ggtgattttg 73981 tttagcggag ttttatcatc cgaactgtca aaaggcaccc ttatcaattt gctgacaaaa 74041 ggattgtcca gaacagcggt cattctttca aaatacacct gcatggtttc ggtatggacg 74101 ataagtatct ctctgtgctt cggactgacc tatggttata cggcgtatct tttcccacaa 74161 ggtgaaacat caaatctgct gttttctgtg ttttgcctat ggctgtttgg cttgttttta 74221 ctggcggcgt tattattttc agccacatta acaagaagca gttatggagg cttgctcata 74281 acaggtgctg ttgtggttgt ttgtatggtt atgaacatca tacccgatgt gcataggtac 74341 aaccctattt ctttagcgac tgataatatg ggattaatca tgaattccac agaggtgtct 74401 tctctttata gtactatcat gatttcctgc ctgctttcat tgatttttgt gttcctttcg 74461 gtagtgatat ttagaaaaaa gcaactgtaa aatgctcact ttgtcagcgg agatgtcgaa 74521 aagccctgta tttttatgtg cccgattgtt tgcgaagaca cataacatgt ccgccggagc 74581 cagacaaagt aaaaaacgtc aaattatata cagttgattg gggttatttt ccttaaagta 74641 tactgttttg ctgccggccg ctgtacacag caagagccat attgattttt aaattgggga 74701 gaaggttaca tacgatgtca agaacagtgc agtacaagaa cgctaaatcg ggatataggg 74761 atatttcgca cacatgactt ggggactgca gtaagtatta atttatacct gtctttacaa 74821 ctaattggca tatattgcta tatacaaaat tcttggtatt tataaaattc tatcgaaaaa 74881 attcgacata ttgtacatag ttatcatatt ttcttaattt gcatttgcca ataataatat 74941 ttaaacatcg taaggaggtt aatatatgtc ccccagtttc cgaaaactta tttttgttct 75001 atgtgcagtg cttgttatag gtggggtatg tttgtattgg attaattcaa gtaaaatgac 75061 aatttccatt aacgaagtac ctatgaaagt ttccaaaagc ctaataatta ctcatgacac 75121 gaaaatttat gtagatgtat tgaaaatgct aagccttcaa gaaatacctt ttcacacagg 75181 tgattttggc ataactgttt tgctcagcgg ttcaaaggtt gtaaggttga atacggaaga 75241 taatatagca gttataaatg gagaaacatt agatttgaca gatgaagatt atatatataa 75301 caaacagaag ctttatctga ctgaagaaac atatagaagg ttgtttgacc aggcaataat 75361 ttaccttccg gaggagaaag taaagtttgc aacctatgat ataggtggct ttaagatacc 75421 acaggatctt acttttgaag aatatttaag tatgactcca gaggaatgcc aaaagctggt 75481 tgtaaggaac tcctacaaca aaaaaatcct tgaatcccag gtaaatacgg ttcctgggga 75541 tgagctgaat cccgttgtaa aagatgcata caatcaagta gtatggagtt ttgatcttta 75601 cagacaattt caattttata attggcatat aggcctcgac gatagcgaag gcttaagcgg 75661 ttacctcttg tgcagtaatg cagaaaccat acttcgtcag tttgaaagaa tgaagatttt 75721 aagagagatt gcaaatatta aagagtttac cactaaagat attgaataca taaatcgcat 75781 taataccttg tataatgcaa tggattttca aaagattaaa ctattgggac cggctattga 75841 gtcttatata gatagattgg acccgtcaac tgaaggatgg gacgtgtata aaagttcggc 75901 ggagaaagca cttgaacagt ttaataaaac atttaaagtt gaaaaaattg ataagttgaa 75961 tattccggct tgggctgaat ttgactctta ttatgtcagc ttaaaatatt ttccgtacgc 76021 agaacaagaa aaaaatttgc atgaaatgct ggatcaaatt cttgataagg tacctgatgg 76081 gattaataat gccattgagt ggagtgaaaa ttatagtgaa atagaaaaaa ttattttaat 76141 ggtatatccg gaatggaaaa gttatctgcc gggcgaggaa ttaattaatg gtctgaaaaa 76201 tggttcattg aaaaaagaag taaagaccct cggaaaagta gttaaaatat acgatggcat 76261 aaatcttttt aacgatgtat taaatcttat ggatacggaa agagacaatg acttttttgc 76321 agaagttaag aaaagcaagg ttgattcggc atcaaatatt ttaaataaaa taataaatcc 76381 agcccaaatg ataaaatccg gtctggaaat gggaaatgca aatttggtta gcatgggtgg 76441 cttgctggga ctggaatttt ttatagctca ggaggtcaca agccgcatag aaaagttggg 76501 caagttcgtt agcggaatgg ttttaatgtc tatggacacc gattctatgg atgatgttta 76561 taacggaaaa atatcgttgg aagaatatct ggatggagag taagctaatt ctggcgctaa 76621 ccattataat atacccgaat ttgacacttg tttataatcc gtaggcttgt ttttaccggc 76681 ggcgttatta ttttcagcca cattaacaag aagcggttat ggatacctga tcataacagg 76741 tgctgtcgtg gttgcctgta tgattatgaa catcataccc gatgtgcata ggtacaaccc 76801 catttcttta gtgactgata atatgggatt aatcatgaac tctatcaatt tcaacagtta 76861 accttattaa tcagccttcg tcggctatcg aacagttcga tacaggaata agtattgttt 76921 cccgatttcg ttctcggctg ggtgcgctgc aaaaccgatt ggaacatgct cttgctatta 76981 gtaatataaa ctccgggaat accgcaagca gtgaagcgag aatacgtgat gctgactgtg 77041 taaaagaaat aacaggtatt atgaggagcc gtattctcag tcaggcttca atgtaactga 77101 agcatggcct ggggagctta ctttcttttc atggcaagat tttgttactg ccattccctc 77161 acccctgttt ttaataacta catataaatc gaatggaaaa gaaaatgctt gtttgcaatc 77221 ctggtcaact tttgtcggtg acagtggtga atttatttgc attatcggct cagtgtcaaa 77281 ggacggacat ttatatcaga gcttaaagga aacaaaatgt tgtgtgttga attttccgtc 77341 ttacgatatt tgtgataaat gtgtccaaac aattaaaaat aacggctttg atgatgacga 77401 gatcaccttg tcgggattga ctgctgaaaa agcgaagact gtaaatgctc cacgcattgc 77461 agagtgtttt cttagcattg aatgtgaatt tttatgggaa cgtgagcatt ttgaaggcag 77521 ccctaatgtg acagtggctc tgagagctac tcatatttgc atggatagcg accattatga 77581 ccaaaacaag cttggcagat acggaaaaac aggatacatg tataatgtac acagcccacg 77641 aaaccctgaa accggcgaag tgacaccgga ctgttttggt gccctggaat tgtacaggtg 77701 atgaggacag gttttgggct gacagatgta aattatttta tatgaaagac cgtggacggc 77761 aaatgattgt tgttaacatg tggatataat atctccaatt tttgaaacat gaagattttt 77821 tgaaacttaa ggtgtttaac cttgaagata ttcaaaaagt tgtaggagtt ttccgagttt 77881 agtttgaaat aaatgaaaaa atacgataca ataaataaaa atcccgagtt tgacagttat 77941 agagcgtaaa agagacgcta aaccttgaaa tttaagggtt tgcgtctctt atctttttat 78001 aaatgaagtt attcaactaa ctttggaaag aaccaaatt //