LOCUS NZ_ACVX01000015 76023 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00031, whole genome shotgun sequence. ACCESSION NZ_ACVX01000015 NZ_ACVX00000000 VERSION NZ_ACVX01000015.1 GI:256004549 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 76023) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 76023) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000015. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..76023 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene <1..493 /locus_tag="ClothDRAFT_1389" CDS <1..493 /locus_tag="ClothDRAFT_1389" /inference="ab initio prediction:Prodigal:1.4" /codon_start=2 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429528.1" /db_xref="GI:256004550" /translation="LLKESEVTYIPNTNWSILSSQQLGRYAEYYSKMEFASYGFEVYT SEVDDHGIDFIAKTKSGVFLEIQVKSIRKLSYVFVQKEKWNIESPNTYLALLIFEDGK FPESYLIPATAWKTPNELFCDRDYVGLKSKLEYGLNISKKNMKLLQEYKMEDVIKDCK VKF" gene 890..1504 /locus_tag="ClothDRAFT_1390" CDS 890..1504 /locus_tag="ClothDRAFT_1390" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429529.1" /db_xref="GI:256004551" /translation="MVNGVDINTGLYPVLNYKPANAQYPYIYVPVAEFSKVGAKVTWN EAKQLLSVTTDYYENQRIIADLKAKISTLEKMPPFNFILTVTKIVGNLSEEQKMEIYG LAETKTLDELRTMSSDAFNQLNETAVSKDGIIDARGGYTGFTMAFVKGDIKLVASVTF YTNDPNLSENYNKYTEQQKEIFNKFSSAAVYVANKFLKEQILAL" gene 1706..3247 /locus_tag="ClothDRAFT_1391" CDS 1706..3247 /locus_tag="ClothDRAFT_1391" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429530.1" /db_xref="GI:256004552" /translation="MYNQSNAGNANHVADSKRPARKKKIGCLGCFGYSLLTILVLAVG LFAFNTIRSKIEEREQQKLEARFDYEEKFSAEEKLTRSFEKGEISADTYVLQLAYSLY DVEKLDPLYKSDNDVDFPPDVVNAVLEHEDELSDETLEYIASKILMTDIKIHPDASQN SVAYKNNWLPFSEYVFAEDEYDVTVLDKAILSPGGKFLIFYTETGKSAVKREVVQELA GSVEKIADDISDFLGIEWDYNFQVLNFESHIHMKKVLNACGIDENAIKKALPVYIYEP PETSGALAWYIRNFNPVEKFGNWLVKVASEENIIEERATVYSVPYIVVKTSSISNMEN LNAILGHELTHHFQRIYYNNLNHNPPDFTNETVANFVSASINKNKGTNTVLNKHANDS MNVLDSHFYTMIDGKACGYLEFVWAKSYVDIIENGKQYLMESLLQEGNPFNFLKEKAG DSYQLVFEDFAVRNITKDYQEKGFISTIFPKPKEWINRYMDGEEHEINFNCLHYYYID ITILM" gene 3385..4008 /locus_tag="ClothDRAFT_1392" CDS 3385..4008 /locus_tag="ClothDRAFT_1392" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429531.1" /db_xref="GI:256004553" /translation="MFADFSKGDYKEYNEIILAFGNCDTTAKAKYQMICLSPATIALY EALTGLKDIDPWEINGDCITINVKDFMKGATTLTDLFARINPYIWAEVIDEDSPDVEE YVEHLQDEINEFGEALKKFGDMFDYKTVRIYVMPIKNSVLSDDEIHDTALKNMPIPRL KVIDKAEDGMHLSMGGSIQPFSKTRLIFYTVITKPDEKIMYRIELEK" gene 4080..4571 /locus_tag="ClothDRAFT_1393" CDS 4080..4571 /locus_tag="ClothDRAFT_1393" /inference="protein motif:COG:COG1011" /note="KEGG: vpa:VPA0709 HAD family phosphatase" /codon_start=1 /transl_table=11 /product="hydrolase (HAD superfamily)-like protein" /protein_id="ZP_05429532.1" /db_xref="GI:256004554" /translation="MRASLGKISSREFWHELGFVNGYEQIEREYLDTCLTLDGEFISI AEELGAEYDLAVLSIDVKEWGKYLREKYNLDRFFREVVISGEVKCRKPDYGIYDILFS RLNVNPQDCVFIDDRYKNLKTASEKGLKTIRFCREPQEKTFEPDAEINSFTQLKEAVR YIW" misc_feature <4227..4544 /locus_tag="ClothDRAFT_1393" /note="Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others...; Region: HAD_like; cl11391" /db_xref="CDD:187016" gene 4916..6448 /locus_tag="ClothDRAFT_1394" CDS 4916..6448 /locus_tag="ClothDRAFT_1394" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; TPR repeat-containing protein; SMART: Elongator protein 3/MiaB/NifB; Tetratricopeptide domain protein; KEGG: bac:BamMC406_5552 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05429533.1" /db_xref="GI:256004555" /db_xref="InterPro:IPR001440" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013026" /translation="MNNPITAVWEITMGCNMRCKHCGSSCENALEGELTTEEALKLCD ELGELGFKWITLSGGEPTTRKDWHLIAKRLNENGIIPNMITNGWLMNEEIADKAVEAG INTVAISVDGLEETHDFIRKKGSFQRIMRAFDILRTRNIFYSAITTINNINIKELPRL RDILIEKGVRGWQLQLGLPMGNMAKNNELVAQPYHIDEVIEFSYKTVKEGYNIDVQLA DCIGYFNLKEIEVRKNSYGGGRDGYNWTGCGAGKYSLGILHNGDILGCTSVRDRSFIE GNIRQTPIKEIWMNPDSFSWNRKMTKDKLSGLCKKCYFGERCLGGCSNTRLTMEGSVY SENRYCSYNVAISTAREQLDRIEDVDVMLSKAKKFADNGNFQLAEILLSRAIEKGCRD IGVFEFYGYISFMLGNYLDAKKANEEALKINPDSAYANKGMGLSLGRLGELEKGIEYL RKAIALSDENFTDPYYDLAVLLYENGRKEEALEVLEEGRKKYKSFIDTSKDLYDILTN AS" misc_feature 4916..5944 /locus_tag="ClothDRAFT_1394" /note="Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535" /db_xref="CDD:30881" misc_feature 4940..5509 /locus_tag="ClothDRAFT_1394" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(4958..4960,4964..4966,4970..4972,4976..4984, 5084..5086,5090..5095,5165..5173,5240..5242,5357..5359, 5441..5446) /locus_tag="ClothDRAFT_1394" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" misc_feature 5894..6190 /locus_tag="ClothDRAFT_1394" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature order(5897..5902,5909..5914,6002..6007,6011..6016, 6023..6028,6104..6109,6116..6121,6128..6133) /locus_tag="ClothDRAFT_1394" /note="binding surface" /db_xref="CDD:29151" misc_feature order(5906..5908,5942..5944,5954..5956,5963..5965, 6011..6013,6047..6049,6059..6061,6068..6070,6113..6115, 6149..6151,6161..6163,6170..6172) /locus_tag="ClothDRAFT_1394" /note="TPR motif; other site" /db_xref="CDD:29151" misc_feature 6113..6376 /locus_tag="ClothDRAFT_1394" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature order(6113..6115,6149..6151,6161..6163,6170..6172, 6215..6217,6251..6253,6263..6265,6272..6274,6320..6322, 6356..6358,6368..6370) /locus_tag="ClothDRAFT_1394" /note="TPR motif; other site" /db_xref="CDD:29151" misc_feature order(6116..6121,6206..6211,6215..6220,6227..6232, 6311..6316,6323..6328,6335..6340) /locus_tag="ClothDRAFT_1394" /note="binding surface" /db_xref="CDD:29151" gene 6459..8642 /locus_tag="ClothDRAFT_1395" CDS 6459..8642 /locus_tag="ClothDRAFT_1395" /inference="protein motif:TFAM:TIGR01193" /note="KEGG: rec:RHECIAT_PB0000366 probable bacteriocin/lantibiotic ABC transporter, ATP-binding protein; TIGRFAM: ABC-type bacteriocin transporter; PFAM: ABC transporter related; peptidase C39 bacteriocin processing; ABC transporter transmembrane region; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="ABC-type bacteriocin transporter" /protein_id="ZP_05429534.1" /db_xref="GI:256004556" /db_xref="InterPro:IPR001140" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005074" /db_xref="InterPro:IPR005897" /db_xref="InterPro:IPR017940" /translation="MLRRLFKKKYVCVRQYDLTDCGAACLSSIAQYYGLKMSLAKIRE MTGTDTQGTNAYGLIHAAKQLGFSAKGVKASKEDLLKDFRLPAIANVIVDNRLAHFVV IYSIKNRIITVADPGKGIVRYSMDDFCSIWTGGLVLLEPGEAFQKGDYTQNMMVKFAG FLKPLKKTVLCIFLASLLYTALGIAGSFYIKFLFDDLIKFEKLNDLHIISAGFAVIFL LQIFLNYYRSILVTKLGMSIDKSIMMEYYSHVLKLPMNFFNSRKVGEIISRFMDASKI RQAISGATLTIMIDTIMAVIGGILLYIQNSSLFFISFIIILLYGIIVTVFNKPIQNAN RQIMEDNAKLTSALVESVKGIETIKSFGAEEQTEKSTRDKIETVMKSSFKEGMLYINL SSLTGIVAGLGGIVILWAGAYNVIKGNMSGGQLLAFNALLAYFLTPVKNLIDLQPLIQ TAVVASNRLGEILELATEKELREDSDDFVISLKGDIEFRNVDFRYGLRKPVLKNINLT IPKGKTVAIVGESGSGKTTLAKLLMNFYSPEKGDILINGHSIKNISLELIRKKIAFVS QDVFIFSGTVKENLCLGNENVDMDEIIKAAKMANAHDFIEKLPLKYDTFLNESGANLS EGQKQRLAIARALLKKPDILILDEATSNLDSITENHIKDAIYGLEDGVTVIIIAHRLS TIVNCDKIYLLKDGEIVESGSHTELIALKGCYFKMWKQTENTLAS" misc_feature 6483..8624 /locus_tag="ClothDRAFT_1395" /note="ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274" /db_xref="CDD:32455" misc_feature 6486..6887 /locus_tag="ClothDRAFT_1395" /note="A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the 'double-glycine' leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418" /db_xref="CDD:30271" misc_feature order(6501..6503,6519..6521,6753..6755,6801..6803) /locus_tag="ClothDRAFT_1395" /note="putative active site; other site" /db_xref="CDD:30271" misc_feature 6963..7730 /locus_tag="ClothDRAFT_1395" /note="ABC transporter transmembrane region; Region: ABC_membrane; cl00549" /db_xref="CDD:186074" misc_feature 7914..8618 /locus_tag="ClothDRAFT_1395" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature 8013..8036 /locus_tag="ClothDRAFT_1395" /note="Walker A/P-loop; other site" /db_xref="CDD:72971" misc_feature order(8022..8027,8031..8039,8157..8159,8397..8402, 8493..8495) /locus_tag="ClothDRAFT_1395" /note="ATP binding site; other site" /db_xref="CDD:72971" misc_feature 8148..8159 /locus_tag="ClothDRAFT_1395" /note="Q-loop/lid; other site" /db_xref="CDD:72971" misc_feature 8325..8354 /locus_tag="ClothDRAFT_1395" /note="ABC transporter signature motif; other site" /db_xref="CDD:72971" misc_feature 8385..8402 /locus_tag="ClothDRAFT_1395" /note="Walker B; other site" /db_xref="CDD:72971" misc_feature 8409..8420 /locus_tag="ClothDRAFT_1395" /note="D-loop; other site" /db_xref="CDD:72971" misc_feature 8481..8501 /locus_tag="ClothDRAFT_1395" /note="H-loop/switch region; other site" /db_xref="CDD:72971" gene 8745..9017 /locus_tag="ClothDRAFT_1396" CDS 8745..9017 /locus_tag="ClothDRAFT_1396" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429535.1" /db_xref="GI:256004557" /translation="MSEAKKLNIGRELTDEELMEMTGGSTFSIQCQKDYTYKPSLPVV KYGVVIDEPEVVIKYGVGPIVGIKYGVEPIGPIQPMYGIKPVETLK" gene 9323..11014 /locus_tag="ClothDRAFT_1397" CDS 9323..11014 /locus_tag="ClothDRAFT_1397" /inference="protein motif:PFAM:PF00150" /note="PFAM: glycoside hydrolase family 5; cellulosome protein dockerin type I; KEGG: azc:AZC_1301 endoglucanase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 5" /protein_id="ZP_05429536.1" /db_xref="GI:256004558" /db_xref="InterPro:IPR001547" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MKKFLVLLIALIMIATLLVVPGVQTSAEGSYADLAEPDDDWLHV EGTNIVDKYGNKVWITGANWFGFNCRERMLLDSYHSDIIADIELVADKGINVVRMPIA TDLLYAWSQGIYPPSTDTSYNNPALAGLNSYELFNFMLENFKRVGIKVILDVHSPETD NQGHNYPLWYNTTITEEIFKKAWVWVAERYKNDDTIIGFDLKNEPHTNTGTMKIKAQS AIWDDSNHPNNWKRVAEETALAILEVHPNVLIFVEGVEMYPKDGIWDDETFDTSPWTG NNDYYGNWWGGNLRGVKDYPINLGKYQSQLVYSPHDYGPIVYEQDWFKGDFITANDEQ AKRILYEQCWRDNWAYIMEEGISPLLLGEWGGMTEGGHPLLDLNLKYLRCMRDFILEN KYKLHHTFWCINIDSADTGGLFTRDEGTPFPGGRDLKWNDNKYDNYLYPVLWKTEDGK FIGLDHKIPLGRNGISISQLSNYTPSVTPSPSATPSPTTITAPPTDTVTYGDVNGDGR VNSSDVALLKRYLLGLVENINKEAADVNVSGTVNSTDLAIMKRYVLRSISELPYK" sig_peptide 9323..9403 /locus_tag="ClothDRAFT_1397" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.414 at residue 27" misc_feature 9464..10555 /locus_tag="ClothDRAFT_1397" /note="Cellulase (glycosyl hydrolase family 5); Region: Cellulase; cl12144" /db_xref="CDD:159804" misc_feature 10826..10888 /locus_tag="ClothDRAFT_1397" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 10922..10984 /locus_tag="ClothDRAFT_1397" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 11088..11759 /locus_tag="ClothDRAFT_1398" CDS 11088..11759 /locus_tag="ClothDRAFT_1398" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: mno:Mnod_8578 two component transcriptional regulator, winged helix family" /codon_start=1 /transl_table=11 /product="two component transcriptional regulator, winged helix family" /protein_id="ZP_05429537.1" /db_xref="GI:256004559" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /translation="MPKILIVEDDKDIVNNLTEYLRDEGFDVDSAGGQNEAINKMDKN KYDLLLVDISLKDGNGFAVCSAARENNDIPVIFLSASDDEYNIVTGLEIGADDYIVKP FRPRELLSRIRKALRRNGKAGAVIEHDNIRVDTVRGIVTKNGSEIFLSALEYRLLLVF LNNKGAVLSRSRLLEEIWNIAGEYVNDNTLTVYIKRLREKIEDDPQNPTFIKTVRGLG YKVGD" misc_feature 11091..11747 /locus_tag="ClothDRAFT_1398" /note="Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745" /db_xref="CDD:31088" misc_feature 11100..11435 /locus_tag="ClothDRAFT_1398" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(11109..11114,11241..11243,11265..11267,11322..11324, 11379..11381,11388..11393) /locus_tag="ClothDRAFT_1398" /note="active site" /db_xref="CDD:29071" misc_feature 11241..11243 /locus_tag="ClothDRAFT_1398" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature order(11250..11255,11259..11267) /locus_tag="ClothDRAFT_1398" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature 11388..11396 /locus_tag="ClothDRAFT_1398" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature 11463..11747 /locus_tag="ClothDRAFT_1398" /note="Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase...; Region: trans_reg_C; cd00383" /db_xref="CDD:29475" misc_feature order(11535..11537,11592..11597,11652..11654,11661..11663, 11685..11690,11724..11726,11739..11741) /locus_tag="ClothDRAFT_1398" /note="DNA binding site" /db_xref="CDD:29475" gene 11752..12768 /locus_tag="ClothDRAFT_1399" CDS 11752..12768 /locus_tag="ClothDRAFT_1399" /inference="protein motif:PFAM:PF02518" /note="PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mxa:MXAN_2785 sensory box histidine kinase/response regulator" /codon_start=1 /transl_table=11 /product="histidine kinase" /protein_id="ZP_05429538.1" /db_xref="GI:256004560" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /translation="MIKVSFFRNPEIKKGFLIFIVLSVVSTSIGFLYDKSVGFFVLCL CFVFTLVHFALTYLRYRKIAEFTREVDRVLHGAESINFGSYSEGELAILESEISKLTI RLREQAEALKKDKTFLADSIADISHQIRTPLTSINILVSQLLKPKLSDEHRIEIAKEL ELMLMRIDWLITALLKMSKIDAEVVRFQRKTVSVAELVRRAIEPIAIPMELKEQQIDV FMEGNETFIGDLSWSVEAIGNILKNCMEHTPKGGRIVIKACENAIFTEIEITDNGPGI DREDLPHLFERFYKGKNSGEHSMGIGLALARMIIVSQNGTIKAQNNHDGGAKFTVRFY KGVV" misc_feature 12115..12300 /locus_tag="ClothDRAFT_1399" /note="Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-...; Region: HisKA; cl00080" /db_xref="CDD:153499" misc_feature 12457..12750 /locus_tag="ClothDRAFT_1399" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature order(12466..12468,12478..12480,12487..12489,12556..12558, 12562..12564,12568..12570,12574..12579,12649..12660, 12706..12708,12712..12714,12727..12732,12736..12738) /locus_tag="ClothDRAFT_1399" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature 12478..12480 /locus_tag="ClothDRAFT_1399" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature order(12568..12570,12574..12576,12649..12651,12655..12657) /locus_tag="ClothDRAFT_1399" /note="G-X-G motif; other site" /db_xref="CDD:28956" gene 12877..13560 /locus_tag="ClothDRAFT_1400" CDS 12877..13560 /locus_tag="ClothDRAFT_1400" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMC domain protein; SMART: AAA ATPase; KEGG: sat:SYN_01994 ABC transporter ATP-binding protein" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429539.1" /db_xref="GI:256004561" /db_xref="InterPro:IPR003395" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /translation="MEILRVENVTKTYGTGENMVRALDGVSFSVKKGEFIAIVGPSGS GKSTLLHILGGVDKPTSGKVFMDGKDVYAQNDEQLAIFRRRQVGLIYQFYNLIPVLNV VENITLPVLMDGRKVNKERLEELIETLNLKGRENHLPNQLSGGQQQRVSIGRALINAP SVVLADEPTGNLDSKNSQEIVELLKLSNKKYNQTLIVITHDENIALQANRVIAIEDGR IIRDEVIRQ" misc_feature 12883..13548 /locus_tag="ClothDRAFT_1400" /note="ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136" /db_xref="CDD:31331" misc_feature 12886..13533 /locus_tag="ClothDRAFT_1400" /note="This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE). They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255" /db_xref="CDD:73014" misc_feature 12994..13017 /locus_tag="ClothDRAFT_1400" /note="Walker A/P-loop; other site" /db_xref="CDD:73014" misc_feature order(13003..13008,13012..13020,13150..13152,13372..13377, 13474..13476) /locus_tag="ClothDRAFT_1400" /note="ATP binding site; other site" /db_xref="CDD:73014" misc_feature 13141..13152 /locus_tag="ClothDRAFT_1400" /note="Q-loop/lid; other site" /db_xref="CDD:73014" misc_feature 13300..13329 /locus_tag="ClothDRAFT_1400" /note="ABC transporter signature motif; other site" /db_xref="CDD:73014" misc_feature 13360..13377 /locus_tag="ClothDRAFT_1400" /note="Walker B; other site" /db_xref="CDD:73014" misc_feature 13384..13395 /locus_tag="ClothDRAFT_1400" /note="D-loop; other site" /db_xref="CDD:73014" misc_feature 13462..13482 /locus_tag="ClothDRAFT_1400" /note="H-loop/switch region; other site" /db_xref="CDD:73014" gene 13557..16163 /locus_tag="ClothDRAFT_1401" CDS 13557..16163 /locus_tag="ClothDRAFT_1401" /inference="protein motif:PFAM:PF02687" /note="PFAM: protein of unknown function DUF214; KEGG: cco:CCC13826_1257 macrolide export ATP-binding/permease protein MacB" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF214" /protein_id="ZP_05429540.1" /db_xref="GI:256004562" /db_xref="InterPro:IPR003838" /translation="MNVFYKLTLKILEKNKARTLVTIVGIILSASMITAVTCFISSLQ DFLVDMVVAREGDWYGVVYDVKKEQIESLKKDKEVKSVVWLRKIGYAWLEGSQNEYKP YLFIGAMGEGFKDSMPIHLTEGRMPESNSEIILPKHVETNGGVKFKIGDILSLEIGDR ISDGFKLNQNNSYLHEKDGGETEELVVRERRTFTVVGFYERPGFEPFIAPGYTALTVE DNNAFSSYDYDVYIKTKKMSGIIDFMDEKFQGHGRRINDDLLRFSGVIYDPTFKGILY GLAGILIALIMFGSILLIYNAFSISVNERTKQFGILASIGATRRQMLKSVLFEACFLS LIGIPFGILAGVLGIGVTLKLTEDLFVSFLQVDNGVVLDLHVSLGAVVVAIVVGFATV LISAYIPAKRALRISPIDAIRQTQDIKIEAKKVKTSKLVYKLFGFEGMIASKNFKRNR RKYRTTVVSLFMSVVLFISSSSFCAYITKSANSVVRRLDYDISYTFTSDLKEKYSFDE LYGELSQINGVADSSYGYFYRDFEYAKIPTGLLNKEYISHLEKRYGENYMETDLEYYL VNIRVYFVDDVTYEKYLKENSLASNTNRNSNVPHAVVVDSMKFYDAQQKKHYTLNLLD EGIHDITVEMLKEREDAAGEKIDIVGVTDSVPLGVQDNLPYMLTVIYPFSAISALQEG KNGEVDVTMYFKTEDHRIVFDRIYKVLNEKGLPVSRLINYAETDEANRALITIVNVFS YGFIVLISLIALANVFNTISTNISLRRREFAMLKSIGMTEKGFSKMMNYECLLYGIKG LMYGIPVSIGVTYLIYRSIAEGLETKFFVPWYSMAITVGSVFIVVFSTMLYSMSKIKK DNPIDALRNENL" sig_peptide 13557..13688 /locus_tag="ClothDRAFT_1401" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.912) with cleavage site probability 0.438 at residue 44" misc_feature <14424..14780 /locus_tag="ClothDRAFT_1401" /note="Predicted permease; Region: FtsX; cl11418" /db_xref="CDD:187029" misc_feature 15621..16133 /locus_tag="ClothDRAFT_1401" /note="Predicted permease; Region: FtsX; cl11418" /db_xref="CDD:187029" gene 16362..17555 /locus_tag="ClothDRAFT_1402" CDS 16362..17555 /locus_tag="ClothDRAFT_1402" /inference="protein motif:PFAM:PF00557" /note="PFAM: peptidase M24; creatinase; KEGG: pca:Pcar_2614 Xaa-Pro aminopeptidase" /codon_start=1 /transl_table=11 /product="peptidase M24" /protein_id="ZP_05429541.1" /db_xref="GI:256004563" /db_xref="InterPro:IPR000587" /db_xref="InterPro:IPR000994" /db_xref="InterPro:IPR001547" /db_xref="InterPro:IPR001714" /translation="MVKRVPLEELKARMERFRTMMNQYNPEWKMAVIFSKINIYYFTG TMPEGMLLIPREDEAVLWVRRSFERAKDESLFPEIRPMNSYRDAVGSYQNLPDTVYLE TEFVPIAMFQRFQKYFPFKNVKPLDMVIAKLRSVKSSYELEIVKQAGEIHKRVLEERV PEILEEGMTEAELATRLFSVMVEEGHQGISRFSMFDTEMVIGHICFGESSIYPTYFNG PGGCYGLSPAVPLLGSRERRLKKGDLVFIDVACGVDGYHTDKTMTYMFGSPLPDEAIE NHKKCVDIQNKIASMLKPGAIPANIYRDIMDSLDEKFHQNFMGFGKRKVKFLGHGIGL QVDEMPVIAEGFNEPLKEGMVLALEPKKGIENVGMVGIENTFIVTGQGGKCITGDNPG LIPLY" misc_feature 16362..17522 /locus_tag="ClothDRAFT_1402" /note="Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006" /db_xref="CDD:30356" misc_feature 16398..16769 /locus_tag="ClothDRAFT_1402" /note="Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321" /db_xref="CDD:144790" misc_feature 16785..17507 /locus_tag="ClothDRAFT_1402" /note="A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate...; Region: APP_MetAP; cd01066" /db_xref="CDD:29969" misc_feature order(17001..17003,17103..17105,17136..17138,17349..17351, 17436..17438,17478..17480) /locus_tag="ClothDRAFT_1402" /note="active site" /db_xref="CDD:29969" gene 17588..18319 /locus_tag="ClothDRAFT_1403" CDS 17588..18319 /locus_tag="ClothDRAFT_1403" /inference="protein motif:PFAM:PF01863" /note="PFAM: protein of unknown function DUF45; KEGG: noc:Noc_2910 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF45" /protein_id="ZP_05429542.1" /db_xref="GI:256004564" /db_xref="InterPro:IPR002725" /translation="MEKVQSISNGTNSISYTLTRSRRKTVGIRITENGEVKVAAPLNI PDRQLKDIILKKLPWILRKQEELRKICEESRLENKFADGETFLYLGKEYTLRIAKGVL PEGVNLEENYIVVAADETKVSVNGPQYIRNVLKNFYVNQFVDIAKTRMDFFSPKIGVC PRKLTVREQKTRWGSCSSKGNISLNWKLVMAPMEVIDYVIVHELCHMKEMNHSKNYWN IVKSIIPDFELRRKWLKDNGHRLLM" misc_feature 17657..18298 /locus_tag="ClothDRAFT_1403" /note="Protein of unknown function DUF45; Region: DUF45; cl00636" /db_xref="CDD:153902" gene 18758..20977 /locus_tag="ClothDRAFT_1404" CDS 18758..20977 /locus_tag="ClothDRAFT_1404" /inference="protein motif:PFAM:PF00759" /note="PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; cellulosome protein dockerin type I; KEGG: hch:HCH_02464 cellulase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 9" /protein_id="ZP_05429543.1" /db_xref="GI:256004565" /db_xref="InterPro:IPR001701" /db_xref="InterPro:IPR001956" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MKKILAFLLTVALVAVVAIPQAVVSFAADFNYGEALQKAIMFYE FQRSGKLPENKRNNWRGDSALNDGADNGLDLTGGWYDAGDHVKFNLPMAYAVTMLAWS VYESRDAYVQSGQLPYILDNIKWATDYFIKCHPSPNVYYYQVGDGALDHSWWGPAEVM QMPRPSFKVDLTNPGSTVVAETAAAMAASSIVFKPTDPEYAATLLRHAKELFTFADTT RSDAGYRAAEGYYSSHSGFYDELTWASIWLYLATGDQSYLDKAESYEPHWERERGTTL ISYSWAHCWDNKLYGSLLLLAKITGKSYYKQCIENHLDYWTVGFNGSRVQYTPKGLAY LDRWGSLRYATTQAFLASVYADWSGCDPAKAAVYKEFAKKQVDYALGSTGRSFVVGFG KNPPRNPHHRTAHSSWSALMTEPAECRHILVGALVGGPDGSDSYVDRLDDYQCNEVAN DYNAGFVGALAKMYEKYGGEPIPNFVAFETPGEEFYVEAAVNAAGPGFVNIKASIINK SGWPARGSDKLSAKYFVDISEAVAKGITLDQITVQSTTNGGAKVSQLLPWDPDNHIYY VNIDFTGINIFPGGINEYKRDVYFTITAPYGEGNWDNTNDFSFQGLEQGFTSKKTEYI PLYDGNVRVWGKVPDGGSEPDPTPTITVGPTPSVTPTSVPGIMLGDVNFDGRINSTDY SRLKRYVIKSLEFTDPEEHQKFIAAADVDGNGRINSTDLYVLNRYILKLIEKFPAEQ" sig_peptide 18758..18841 /locus_tag="ClothDRAFT_1404" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.984 at residue 28" misc_feature 18812..20140 /locus_tag="ClothDRAFT_1404" /note="endoglucanase; Region: PLN02308" /db_xref="CDD:177943" misc_feature 18848..20140 /locus_tag="ClothDRAFT_1404" /note="Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959" /db_xref="CDD:186543" misc_feature 20210..20467 /locus_tag="ClothDRAFT_1404" /note="Cellulose binding domain; Region: CBM_3; pfam00942" /db_xref="CDD:109977" misc_feature 20765..20824 /locus_tag="ClothDRAFT_1404" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 20882..20944 /locus_tag="ClothDRAFT_1404" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 21172..22047 /locus_tag="ClothDRAFT_1405" CDS 21172..22047 /locus_tag="ClothDRAFT_1405" /EC_number="3.1.3.16" /inference="protein motif:PRIAM:3.1.3.16" /note="KEGG: dar:Daro_3360 protein phosphatase 2C-like; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein" /codon_start=1 /transl_table=11 /product="protein serine/threonine phosphatase" /protein_id="ZP_05429544.1" /db_xref="GI:256004566" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR014045" /translation="MLKRSFAIGALTDIGNVKKTNEDNILVKVGDEKNGEFGLFLVAD GMGGLAAGEVASGIIVNEFNLWWERQLPGILNQEGNTVLDTDTVLNAISWELDRLIQD INKKIIRFGLSINAKVGSTLTLLFIYQNKYLIKHVGDSRIYRINSSITKLTEDHSWVA QQVKEGKIKEEEAKYHPKRNILTRCLGVMENLEIFEACGDISDDDGFLVCSDGFHNYL DEHEIYCSLSSCKKEDADVQKTLRELLEIVKLRGAADNISAVAVCQHIYRDYSDSILN IKGIINRITGNFGGW" misc_feature 21193..21960 /locus_tag="ClothDRAFT_1405" /note="Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143" /db_xref="CDD:29062" misc_feature 21196..21942 /locus_tag="ClothDRAFT_1405" /note="Protein phosphatase 2C; Region: PP2C; pfam00481" /db_xref="CDD:144174" misc_feature order(21223..21225,21235..21240,21301..21309,21805..21807, 21934..21936) /locus_tag="ClothDRAFT_1405" /note="active site" /db_xref="CDD:29062" gene 22153..22581 /locus_tag="ClothDRAFT_1406" CDS 22153..22581 /locus_tag="ClothDRAFT_1406" /inference="similar to AA sequence:KEGG:Pcar_1745" /note="KEGG: pca:Pcar_1745 Flp pilus assembly protein, protease CpaA" /codon_start=1 /transl_table=11 /product="Flp pilus assembly protein, protease CpaA" /protein_id="ZP_05429545.1" /db_xref="GI:256004567" /translation="MFIGIVTNLVLDGVRGLLDSLLGIIVPFLLLIVLYALRMLGAGD VKLFSAIGAVLGVRAALWIMAYSFLAGGVIALIILIINRNGKERLMHLFNYLKTVFLT FSIQPYTNFEDKDGKAVFRMTYAITCGVMVFFVEVMLKMK" misc_feature <22153..22356 /locus_tag="ClothDRAFT_1406" /note="Type IV leader peptidase family; Region: Peptidase_A24; cl02077" /db_xref="CDD:154734" gene 22624..23043 /locus_tag="ClothDRAFT_1407" CDS 22624..23043 /locus_tag="ClothDRAFT_1407" /inference="protein motif:PFAM:PF01475" /note="PFAM: ferric-uptake regulator; KEGG: gsu:GSU1379 ferric uptake regulation protein Fur" /codon_start=1 /transl_table=11 /product="ferric uptake regulator, Fur family" /protein_id="ZP_05429546.1" /db_xref="GI:256004568" /db_xref="InterPro:IPR002481" /translation="MGKTTDDILAKIGCKNTKSRKAVIEVLENAENPLSAEDIFLCIK KQGSSVNLSTVYRTLDLMESKSVVNKIVMMDGKARYELTVDGHRHHLVCTNCHKSVPI DFCPLENMEKDIGMRSDFDITGHKIEIYGICPNCKKE" misc_feature 22675..23022 /locus_tag="ClothDRAFT_1407" /note="Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153" /db_xref="CDD:133478" misc_feature order(22720..22722,22864..22866,22885..22887,22891..22893, 22924..22926) /locus_tag="ClothDRAFT_1407" /note="metal binding site 2; metal-binding site" /db_xref="CDD:133478" misc_feature 22774..22818 /locus_tag="ClothDRAFT_1407" /note="putative DNA binding helix; other site" /db_xref="CDD:133478" misc_feature order(22882..22884,22888..22890,22945..22947,22996..22998) /locus_tag="ClothDRAFT_1407" /note="metal binding site 1; metal-binding site" /db_xref="CDD:133478" misc_feature order(22897..22905,22951..22956,22981..22989,22993..23019) /locus_tag="ClothDRAFT_1407" /note="dimer interface; other site" /db_xref="CDD:133478" misc_feature order(22900..22902,22909..22911,23020..23022) /locus_tag="ClothDRAFT_1407" /note="structural Zn2+ binding site; other site" /db_xref="CDD:133478" gene 23219..24175 /locus_tag="ClothDRAFT_1408" CDS 23219..24175 /locus_tag="ClothDRAFT_1408" /inference="protein motif:PFAM:PF01297" /note="PFAM: periplasmic solute binding protein; KEGG: gur:Gura_0046 periplasmic solute binding protein" /codon_start=1 /transl_table=11 /product="periplasmic solute binding protein" /protein_id="ZP_05429547.1" /db_xref="GI:256004569" /db_xref="InterPro:IPR006127" /db_xref="InterPro:IPR006128" /db_xref="InterPro:IPR006129" /translation="MRKNTKKVAFLVACLVFLITGCFGNSKVGERKDSDKINVYASFY TMYDFANKIGGDRINLVNIMPAGTEPHHWEPSPKDILEIEKADVFIYNGAGMEPWVEK VLGSITNKELVVVETSKNIELLRGGHYHDEENAEEESDGHDDLAYDPHVWLSPKNAKK QMEAIKDAFVKADPENKEYYEKNFEDNVKKLDDLDREYREELAKYTKKDIVVGHQAYG YLCKEYGLRQYAIEGLNAESEPTPARMAEIVKFIKENDIKVIFSEKLLSQKVPNAIAA ETGVRVEFLNPLGGLTQEEIDSGKEYFTVMRENLEALKKAFE" sig_peptide 23219..23293 /locus_tag="ClothDRAFT_1408" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.802 at residue 25" misc_feature 23318..24172 /locus_tag="ClothDRAFT_1408" /note="Metal binding protein AcdA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017" /db_xref="CDD:29736" misc_feature order(23429..23431,23666..23668,23858..23860,24083..24085) /locus_tag="ClothDRAFT_1408" /note="metal-binding site" /db_xref="CDD:29736" gene 24201..24980 /locus_tag="ClothDRAFT_1409" CDS 24201..24980 /locus_tag="ClothDRAFT_1409" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tdn:Suden_2064 ABC transporter-related protein" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429548.1" /db_xref="GI:256004570" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /translation="MGKVIEVNDLSFGYGERLIFKNVGFSVEKGDFVGIIGPNGSGKS TLIKLLLRQLKPIKGQIKLLGQDIEKFDQWNKIGYVAQKANSFNTSFPATVEEVVSAN LFPKIGLFKRIKNKHRELVYKALETVGMEEYKDRLIGNLSGGQQQRVFIARALVSEPE LIFLDEPTVGIDSESEGALYCLLGRLNQEKKITIVMVTHDIGAVIVHTNKIAYVGDKG LVMNENTKDFVKNNLGGVYGYDVNFHANRHCCTNCWKKGAV" misc_feature 24201..24914 /locus_tag="ClothDRAFT_1409" /note="ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121" /db_xref="CDD:31318" misc_feature 24216..24863 /locus_tag="ClothDRAFT_1409" /note="ABC component of the metal-type transporters. This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-...; Region: ABC_Metallic_Cations; cd03235" /db_xref="CDD:72994" gene 24981..25835 /locus_tag="ClothDRAFT_1410" CDS 24981..25835 /locus_tag="ClothDRAFT_1410" /inference="protein motif:PFAM:PF00950" /note="PFAM: ABC-3 protein; KEGG: tdn:Suden_2063 hypothetical protein" /codon_start=1 /transl_table=11 /product="ABC-3 protein" /protein_id="ZP_05429549.1" /db_xref="GI:256004571" /db_xref="InterPro:IPR001626" /translation="MFGIFGEDFILNLGFMQRAYFIGMLIAIMAPAIGVIIVLRRQSM IGDSLSHTSLAGVAFGLIAGINPIVGATLFSITAALGIEKIRRAFPKYAEVSIAVIMS TGIGLAGVLSGYVKSGFSLSSYLFGSIIAISDFELCVIVVLSAVVIVTFAALFKELFF ITFDEEAARLAGVPVKMINFVFAVLTAVTIAVSSRIVGTLVISSLLVLPPASAMQIAK SFKQTIVYSLLYGIFSIVTGLTLSFYLDMVPGGTIVLISVICLVLTLVYKNLVKGLIA KKVLTGTN" misc_feature 25026..25760 /locus_tag="ClothDRAFT_1410" /note="Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist...; Region: TM_ABC_iron-siderophores_like; cd06550" /db_xref="CDD:119348" misc_feature order(25080..25082,25092..25100,25434..25439,25443..25451, 25455..25460,25464..25481,25485..25493,25617..25619, 25638..25640) /locus_tag="ClothDRAFT_1410" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119348" misc_feature order(25095..25097,25101..25103,25116..25118,25257..25259, 25263..25268,25275..25280,25287..25292,25299..25301, 25308..25313,25317..25319,25350..25355,25362..25364, 25584..25586,25740..25742,25749..25754) /locus_tag="ClothDRAFT_1410" /note="dimer interface; other site" /db_xref="CDD:119348" misc_feature order(25317..25319,25386..25388,25560..25562,25572..25574, 25707..25709,25731..25733) /locus_tag="ClothDRAFT_1410" /note="putative PBP binding regions; other site" /db_xref="CDD:119348" gene 26003..27907 /locus_tag="ClothDRAFT_1411" CDS 26003..27907 /locus_tag="ClothDRAFT_1411" /inference="protein motif:PFAM:PF00183" /note="PFAM: heat shock protein Hsp90; ATP-binding region ATPase domain protein; KEGG: pca:Pcar_1764 heat shock protein 90" /codon_start=1 /transl_table=11 /product="heat shock protein Hsp90" /protein_id="ZP_05429550.1" /db_xref="GI:256004572" /db_xref="InterPro:IPR001404" /db_xref="InterPro:IPR003594" /translation="MNRESGCISIHTENIFPIIKKWLYSEKDIFIRELVSNGSDAISK LKKLVSIGEAEVDGNEKYYIKVVVDKEKKTLQIIDNGIGMTGEEVKKYINQIAFSGIK DFVEKYKDKGEEAQIIGHFGLGFYSAFMVSSKVQIDTLSYQKGAQAVRWISTSGIEYE MEDSDRTERGTTVTLYIAEDSEEFLDFYKVRETLVKYFSFLPYEIYLEDANAAKEDKK EGGDNEEKKAEEPKPINDTNPLWLKNPKDCTEQEYKDFYKKVFFDFNDPLFWIHLNMD YPFNLKGILYFPKLRNEIDNFDGKIKLFCNQVFVAENIKEVIPEFLMLLKGTIDCPDL PLNVSRSFLQNDGYVNKISNHITKKVADKLISIFENERESYNKYWDDINPFVKFGCIK EKKFYERVKDIIIFKTTGGEYVTLKDYLERNKDKHENKVFYVTDEKQQAQYIKMFKDN NMEAVMMNTVIDTHFIQFMEMNNSGVKFLRIDADLSESMKDKENNVDENSQKEISEAL EKMFKESLNNDKLRIKVEALKSSALPGMILISEQARRIQEMSRWYGGFNLEGLYAEEE TLVLNSNSGLIKSLLNLKDKEDRKEDVKLICEHIYDLAKMSHKQLEPDDMTKFIERSN SLLTKLASGL" misc_feature 26003..27898 /locus_tag="ClothDRAFT_1411" /note="heat shock protein 90; Provisional; Region: PRK05218" /db_xref="CDD:179965" misc_feature 26093..26533 /locus_tag="ClothDRAFT_1411" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075" /db_xref="CDD:185789" gene complement(28084..29748) /locus_tag="ClothDRAFT_1412" CDS complement(28084..29748) /locus_tag="ClothDRAFT_1412" /inference="protein motif:PFAM:PF00501" /note="PFAM: AMP-dependent synthetase and ligase; KEGG: pca:Pcar_1242 acetyl-CoA synthetase" /codon_start=1 /transl_table=11 /product="AMP-dependent synthetase and ligase" /protein_id="ZP_05429551.1" /db_xref="GI:256004573" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR000875" /translation="MLEKYLSKVNFNSYDDFVQNFKLNIPENFNFAYDVADEIADKTP EKVALVWCNDRGEEATFTFGQLKEYSNKAANFFKRVGIKKGDRVMLILKRRYEFWFAI LALHKIGAACIPATHLLTAKDIIYRNNAADIKMIVCVGEDEVIKHVEESLEQSPTVMA KALIGRDKEGWYNFNKEIENESSHFERPTGKDATTNDDIMLLYFTSGTTGMPKMVAHD FTYPLGHIVTAKYWQNVIDGGLHLTVADTGWAKAAWGKIYGQWIAGSAVFVYDYDNKF VPKDLLDVICKYGVTTFCAPPTIYRFFIKEDLTKYDFSKLKYCTVAGEPLNPEVYNQF YKATGIKLMEGYGQTELTLTIGTFPWMEPKPGSMGKPSAGYVIDILDENGNPCEVGEE GQIVIRTDKSKPIGMFDGYYRDTELTKKVWHDDIYYTGDMAWRDEDGYFWFVGRADDV IKSSGYRIGPFEVESALLEHPAVLECAITAVPDPIRGQVVKATVVLAKNYSPCDELVK ELQEHVKKVTAPYKYPRIIEFVDELPKTISGKIRRVEIRNKDQAKK" misc_feature complement(28108..29685) /locus_tag="ClothDRAFT_1412" /note="Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365" /db_xref="CDD:30714" misc_feature complement(28114..>29148) /locus_tag="ClothDRAFT_1412" /note="Acyl-protein synthetase, LuxE; Region: LuxE; cl10450" /db_xref="CDD:186997" gene complement(29764..30315) /locus_tag="ClothDRAFT_1413" CDS complement(29764..30315) /locus_tag="ClothDRAFT_1413" /inference="protein motif:PFAM:PF07883" /note="PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pca:Pcar_1243 transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, XRE family" /protein_id="ZP_05429552.1" /db_xref="GI:256004574" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR013096" /translation="MSEQIKQISKRIKELREISGISAETLARELGIDSKTYTEYESGN VDIPVSLLFKIAGRFNVELSEILTGEAPKLHTYCVVRKDKGVSVERRKDYKYQSLAYN FANKKIEPFLVTVEPDSNSEVNYNSHPGQEFNYVIEGVLKVIINGHEIILNEGDSLFF DSGAKHGMKAMNGKPAKFLAIIL" misc_feature complement(29776..30315) /locus_tag="ClothDRAFT_1413" /note="DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943" /db_xref="CDD:182158" misc_feature complement(30118..30291) /locus_tag="ClothDRAFT_1413" /note="Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093" /db_xref="CDD:28977" misc_feature complement(order(30190..30192,30265..30267,30277..30279)) /locus_tag="ClothDRAFT_1413" /note="non-specific DNA binding site; other site" /db_xref="CDD:28977" misc_feature complement(order(30193..30195,30268..30270)) /locus_tag="ClothDRAFT_1413" /note="salt bridge; other site" /db_xref="CDD:28977" misc_feature complement(order(30187..30192,30202..30204,30211..30213, 30244..30249)) /locus_tag="ClothDRAFT_1413" /note="sequence-specific DNA binding site; other site" /db_xref="CDD:28977" misc_feature complement(29770..29985) /locus_tag="ClothDRAFT_1413" /note="Cupin domain; Region: Cupin_2; cl09118" /db_xref="CDD:186830" gene complement(30468..31367) /locus_tag="ClothDRAFT_1414" CDS complement(30468..31367) /locus_tag="ClothDRAFT_1414" /inference="protein motif:PFAM:PF03466" /note="PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bbr:BB0462 LysR family transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, LysR family" /protein_id="ZP_05429553.1" /db_xref="GI:256004575" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /translation="MDINFELYKIFYHTAKAKSFSAAADTLHVSQSAVSQSIKSLEEK LGSKLFFRKNREIKLTAEGEILFKHIEQAYNFIKTAEHKIYQTQNMERGEIRIGASDT VCKYFLIPYIEKFIKNYPNIKIQVINRTSSQIEEILKKGLIDFGIVTLPVQDSNKIHH EEFLTVKDIFVASDKFSMLKNQETDIKTLASYPLLMLDRGTSTRRNIDSYLSSKGIGI VPEIELESIDLLVEFAKIGLGIALVLKESVADELKKGTLFEVKLKEDITLRKLGIITM KNVPLSRASSEFIKLLRTHSNPM" misc_feature complement(30483..31361) /locus_tag="ClothDRAFT_1414" /note="Transcriptional regulator [Transcription]; Region: LysR; COG0583" /db_xref="CDD:30928" misc_feature complement(31176..31355) /locus_tag="ClothDRAFT_1414" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" misc_feature complement(30492..31088) /locus_tag="ClothDRAFT_1414" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466" /db_xref="CDD:176102" misc_feature complement(order(30660..30665,30669..30674,30690..30707, 30984..31004,31008..31010,31020..31022,31029..31034, 31038..31043)) /locus_tag="ClothDRAFT_1414" /note="dimerization interface; other site" /db_xref="CDD:176102" gene 31487..35257 /locus_tag="ClothDRAFT_1415" CDS 31487..35257 /locus_tag="ClothDRAFT_1415" /EC_number="6.3.5.3" /inference="protein motif:TFAM:TIGR01857" /note="KEGG: dno:DNO_1110 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein" /codon_start=1 /transl_table=11 /product="phosphoribosylformylglycinamidine synthase" /protein_id="ZP_05429554.1" /db_xref="GI:256004576" /db_xref="InterPro:IPR010141" /db_xref="InterPro:IPR010918" /translation="MVRRVFVEKKKGFDLEAQRMYRDLKENLRIAGLSGVRLINRYDV EGISDEEYESAKRTIFSEPPVEEVFDETISIDEKDKIVAIEYLPGQYDQRADSASQCI QILTHGERPNVKVAKLIVLQGDVSQEEYEKVKKYLINPVECQEASLEKPSTLDVEVTV PEDVKVLKGFVNMSREELKAFADSMGLAMSLEDLEFCQKYFRDDEKRDPTITEIRVID TYWSDHCRHTTFLTRIQNVDIQEGRFTAPVKEAYESYLQSRKFVYGDKEKDVCLMDIA VMGMRELKKRGLLNDLDESDEVNACSIVVNVDVNGKNEEWLVMFKNETHNHPTEIEPF GGAATCLGGAIRDPLSGRSYVYQAMRVTGSGDPRTSIDDTLPGKLPQRKITTEAAQGY SSYGNQIGLATGQVAEIYDEDFVAKRMEIGAVIGAAPRKNVKREKPKAGDVIILLGGR TGRDGCGGATGSSKEHTEESLLTCGAEVQKGNPITERKIQRLFRKPEVSTMIKKCNDF GAGGVSVAIGELAEGLRINLDAVPKKYEGLDGTELAISESQERMAVMVAKENVDAFIK ASKEENLEATPVAEVTDDRRLVMYWRGKAIVDIKRDFLDTNGVKQNTNVLVAAPLEEE YYFAGIPKEAEDYSKDLRDAWIRNLQRLNVCSQKGLVERFDSTIGAGTVLMPFGGKYQ LTPSEGMAAKIPVPDGDTNTGTLMAFGYNPSIAKWSPFHGAMFAVIESVAKIVAMGGN HKKIRLSLQEYFEKLGKDPKKWGKPFSALLGAYYAQTKIGIPAIGGKDSMSGTFKDMN VPPTLVSFAVATMDVNYTVSSEFKKAGSKVVLIPLKINENGVPDFAQLDKNYAAVHQM IMNRKVLAAHTVRSGGISEAISKMCFGNMIGFKFEASVDARRLFEPLYGSIVLELDES LNLDELLKDVEYEFLGVTQEKTTIDFGNVGLDLVELCQKWQEPLEKVFPTATEPVSST PKQYKFEKRNSIKPSVSIAKPRIFMPIFPGTNCEYDTARAFEKAGGVVDMLVIKNLTP SEIDESIREMAKRIDNSQIVMIPGGFSGGDEPDGSGKFIATAFRNPRVKDAVMRLLKE RDGLMLGICNGFQALIKLGLVPYGEIRDLNEDSPTLTFNTIGRHVSCMVRTKITSTLS PWFNNVKVGDIHTIAVSHGEGRFVASKEVLEMMEKNGQIATQYVDLDGNATYDIRFNP NGSFEAIEGITSPDGRVLGKMGHSERIGTNVAKNVPGDKDQKLFEAGVNYFK" misc_feature 31493..35251 /locus_tag="ClothDRAFT_1415" /note="phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857" /db_xref="CDD:130916" misc_feature 32123..>32197 /locus_tag="ClothDRAFT_1415" /note="AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal...; Region: PurM-like; cl10019" /db_xref="CDD:158822" misc_feature 32432..33283 /locus_tag="ClothDRAFT_1415" /note="PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP...; Region: PurL_repeat1; cd02203" /db_xref="CDD:100034" misc_feature order(32435..32446,32450..32452,32525..32527,32555..32557, 32564..32566,32573..32575,32705..32707,32738..32743, 32753..32755) /locus_tag="ClothDRAFT_1415" /note="dimerization interface; other site" /db_xref="CDD:100034" misc_feature order(32513..32515,32525..32527,32699..32707) /locus_tag="ClothDRAFT_1415" /note="ATP binding site; other site" /db_xref="CDD:100034" misc_feature 33545..34210 /locus_tag="ClothDRAFT_1415" /note="PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP...; Region: PurL_repeat2; cd02204" /db_xref="CDD:100035" misc_feature order(33593..33604,33608..33610,33683..33685,33719..33721, 33728..33730,33740..33742,33845..33847,33887..33892, 33902..33904) /locus_tag="ClothDRAFT_1415" /note="dimerization interface; other site" /db_xref="CDD:100035" misc_feature order(33671..33673,33683..33685,33839..33847) /locus_tag="ClothDRAFT_1415" /note="ATP binding site; other site" /db_xref="CDD:100035" misc_feature 34484..35242 /locus_tag="ClothDRAFT_1415" /note="Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740" /db_xref="CDD:153211" misc_feature order(34649..34654,34664..34666,34775..34777,34787..34789, 34973..34978,35159..35161,35165..35176) /locus_tag="ClothDRAFT_1415" /note="putative active site; other site" /db_xref="CDD:153211" misc_feature order(34775..34777,35165..35167,35171..35173) /locus_tag="ClothDRAFT_1415" /note="catalytic triad; other site" /db_xref="CDD:153211" gene 35539..36780 /locus_tag="ClothDRAFT_1416" CDS 35539..36780 /locus_tag="ClothDRAFT_1416" /inference="protein motif:PFAM:PF00639" /note="PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: dal:Dalk_3808 PpiC-type peptidyl-prolyl cis-trans isomerase" /codon_start=1 /transl_table=11 /product="PpiC-type peptidyl-prolyl cis-trans isomerase" /protein_id="ZP_05429555.1" /db_xref="GI:256004577" /db_xref="InterPro:IPR000297" /translation="MKKSKSIILVISIVVVLIAGLSVATYFILKPLFGEKDESNISPI TKQLTEEEASKVIAEVNGEQILYKDFYFIYSQQAAYYGLTTEDEDSLSDDTKEILNTI KKELLTQLIQQKLAKQKAKEAGYEVTKERLDEASEAIEEMIRNMAEQMKLSSPSEAES RDFLKEARDFINSELKAMRITMDEYIRDTAEYMIVTDFMEDLTKDIVVTDEEIKKYYD EQLKIQQENPEEAAYAEVQLIQPASSRVKHILIALPEEEQQEYQNLKSEGKDEEAEAY LKEKLEAIKPKAEEVLNKAKNGEDFEALIKEYGEDPGMESEQYKDGYTVTKNSGFIKS FEDASLALGVGEISDLVEGPYGYHIIKVYEKTEAKPYTQEEKKSEIESLLKSQKKTNF MNEKMKEWESASTIVRHDDLL" sig_peptide 35539..35613 /locus_tag="ClothDRAFT_1416" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.939 at residue 25" misc_feature <36052..36777 /locus_tag="ClothDRAFT_1416" /note="peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059" /db_xref="CDD:178832" misc_feature 36280..36630 /locus_tag="ClothDRAFT_1416" /note="PPIC-type PPIASE domain; Region: Rotamase; cl08278" /db_xref="CDD:186815" gene complement(36843..38684) /locus_tag="ClothDRAFT_1417" CDS complement(36843..38684) /locus_tag="ClothDRAFT_1417" /EC_number="6.3.5.4" /inference="protein motif:TFAM:TIGR01536" /note="KEGG: scl:sce4939 hypothetical protein; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II" /codon_start=1 /transl_table=11 /product="asparagine synthase (glutamine-hydrolyzing)" /protein_id="ZP_05429556.1" /db_xref="GI:256004578" /db_xref="InterPro:IPR000583" /db_xref="InterPro:IPR001962" /db_xref="InterPro:IPR006426" /translation="MCGIAGWINLKSDLTNQKEILNSMIDRLTPRGPDASGSWISPNA LIAHKRLIVVDPEGGIQPMVRRQGENTYVITYNGELYNTADLRNELESRGHEFLTSSD TEVLLVSYIEWGAKCVEHLNGIYAFGIWDEGKKRLFLGRDRFGVKPLFYAQRGDSLIF GSELKALLANPLVEPKLDAEGLAEIFALGPARTPGHGIFKDVYELKPAHSMIFDINGI QIRKYWSLESYPHTDSEKATISKVRDLVLDAITRQLVADVPVCTFLSGGLDSSAITAV ASKTFASQGKGQLNTFSVDYVDNDIYFKPSMFQPNSDEPWIKKMSESFNTCHHYVKFD TPQLVDALIDAVKARDLPGMADIDSSLFLFCREVKKFSVVALSGECADEIFGGYPWFH NEKMLFADTFPWSVSVHERTKILSPEILNLIKPEEYIQRRYRETLSEVPHLKGENRIE ARRREIFYLNINWFMATLLDRKDRMSMASGLEVRVPFCDHRLVQYVWNIPWELKMYNK REKGLLRQALKGILPDDIIERKKSPYPKTHNPSYKKAVSKWLLEILNDSSSPLHQLID VKVVRSMAEGNSDNTDPWFGQLMAQPQMLAYLIQVDFWLRDNHISIV" misc_feature complement(38010..38681) /locus_tag="ClothDRAFT_1417" /note="Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a...; Region: AsnB; cd00712" /db_xref="CDD:48476" misc_feature complement(order(38379..38381,38448..38456,38535..38537, 38679..38681)) /locus_tag="ClothDRAFT_1417" /note="active site" /db_xref="CDD:48476" misc_feature complement(37083..38675) /locus_tag="ClothDRAFT_1417" /note="asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536" /db_xref="CDD:162406" misc_feature complement(order(38538..38540,38577..38591,38598..38600, 38607..38609,38631..38633)) /locus_tag="ClothDRAFT_1417" /note="dimer interface; other site" /db_xref="CDD:48476" misc_feature complement(37080..37958) /locus_tag="ClothDRAFT_1417" /note="The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes...; Region: Asn_Synthase_B_C; cd01991" /db_xref="CDD:30178" misc_feature complement(order(37548..37556,37593..37595,37797..37805, 37890..37898)) /locus_tag="ClothDRAFT_1417" /note="Ligand Binding Site; other site" /db_xref="CDD:30178" misc_feature complement(order(37548..37556,37593..37595,37797..37805, 37890..37898)) /locus_tag="ClothDRAFT_1417" /note="Molecular Tunnel; other site" /db_xref="CDD:30178" gene 38991..39761 /locus_tag="ClothDRAFT_1418" CDS 38991..39761 /locus_tag="ClothDRAFT_1418" /inference="protein motif:PFAM:PF01522" /note="PFAM: polysaccharide deacetylase; KEGG: wri:WRi_006610 polysaccharide deacetylase, putative" /codon_start=1 /transl_table=11 /product="polysaccharide deacetylase" /protein_id="ZP_05429557.1" /db_xref="GI:256004579" /db_xref="InterPro:IPR002509" /translation="MKFYVVKVNNLIKYAFLAVIVLAVSFFVYFSREDVVGAFQQKRE IPIYSVDYPEKKVALTFDCAWGSEDIPDILNTLREHDVKATFFIIGVWAEKNPDEVKM IADEGHDVANHSYSHYKMSSLNSSAIKSEILKCDRVLKKITGKDVELFRPPYGDYNND VVRIARELNHYTIQWDVDSLDWKPGITAEEIKNRVLKNVNKGSIILFHNDTKHTAKIL PEIITSLKQKGYGFIPVSQMIMRENYEIDYRGRQIKKQ" misc_feature 39138..39707 /locus_tag="ClothDRAFT_1418" /note="Polysaccharide deacetylase; Region: Polysacc_deac_1; cl12061" /db_xref="CDD:164326" gene 39789..40523 /locus_tag="ClothDRAFT_1419" CDS 39789..40523 /locus_tag="ClothDRAFT_1419" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: SAP DNA-binding domain-containing protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429558.1" /db_xref="GI:256004580" /translation="MIFILLHKIKKKVHYKITVYQKKWGLNRVLITAIVGQNDKEKTA NVINSILHNSKKRISIVDSKNLSGLDGKRLKSYLAELERNNTDILILKLDLTDVSKEI YDYLRFDIIVFTDKADEINGEIEQNYMDLMKRAFSLLKEKGIAIVNADDNELNKFFKD IKHYIVTYGFNLKASMTTSSIGDLVAKDNMLCCLQRRIYTKNGTVIEPQEFKVKTDLE SVDPNNVLAAATFVLVNGFDINQMKN" misc_feature 39837..>40496 /locus_tag="ClothDRAFT_1419" /note="UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085" /db_xref="CDD:162196" misc_feature <40164..>40301 /locus_tag="ClothDRAFT_1419" /note="Mur ligase middle domain; Region: Mur_ligase_M; pfam08245" /db_xref="CDD:149357" gene 40876..41592 /locus_tag="ClothDRAFT_1420" CDS 40876..41592 /locus_tag="ClothDRAFT_1420" /inference="protein motif:PFAM:PF00436" /note="PFAM: single-strand binding protein/Primosomal replication protein n" /codon_start=1 /transl_table=11 /product="single-strand binding protein/Primosomal replication protein n" /protein_id="ZP_05429559.1" /db_xref="GI:256004581" /db_xref="InterPro:IPR000424" /translation="MVGNIIENNMVTISGKIVSEAVFSHEVYGEGFYCFTLEVPRLSE CTDKINVTVSERLISKESLQIGKLIEVEGQFRSYNNYDNPEGSKLILTVFAREIRFLE DDKKIKNPNQIFLNGFICKKPVYRTTPFGREITDILLAVNRPYNKSDYIPCICWGRNA RYSAGLEVGQNIKIWGRIQSREYQKKLDTGEVVTKVAFEVSVSKMEVCDKINRKVEPK EEQEEKQEERQEEKTEAMKN" misc_feature 40876..41514 /locus_tag="ClothDRAFT_1420" /note="single-stranded DNA-binding protein; Provisional; Region: PRK05813" /db_xref="CDD:180272" misc_feature 40906..41178 /locus_tag="ClothDRAFT_1420" /note="Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930" /db_xref="CDD:186873" misc_feature order(40909..40911,41077..41079,41083..41085,41089..41091, 41170..41172) /locus_tag="ClothDRAFT_1420" /note="generic binding surface II; other site" /db_xref="CDD:72945" misc_feature order(40924..40932,40975..40986,40990..40992,41023..41031, 41035..41037,41074..41076,41095..41103,41149..41157) /locus_tag="ClothDRAFT_1420" /note="generic binding surface I; other site" /db_xref="CDD:72945" misc_feature 41212..41496 /locus_tag="ClothDRAFT_1420" /note="SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496" /db_xref="CDD:72968" misc_feature order(41212..41223,41296..41304,41320..41322,41326..41328, 41386..41388,41413..41415,41458..41460,41467..41469) /locus_tag="ClothDRAFT_1420" /note="dimer interface; other site" /db_xref="CDD:72968" misc_feature order(41227..41235,41251..41253,41281..41283,41302..41307, 41314..41319,41323..41325,41329..41331,41335..41337, 41341..41343,41377..41382,41404..41406,41410..41412, 41416..41421,41470..41472,41476..41478) /locus_tag="ClothDRAFT_1420" /note="ssDNA binding site; other site" /db_xref="CDD:72968" misc_feature order(41386..41388,41392..41394,41398..41400,41491..41493) /locus_tag="ClothDRAFT_1420" /note="tetramer (dimer of dimers) interface; other site" /db_xref="CDD:72968" gene complement(41711..43486) /locus_tag="ClothDRAFT_1421" CDS complement(41711..43486) /locus_tag="ClothDRAFT_1421" /inference="protein motif:PFAM:PF00070" /note="PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; TQO small subunit DoxD; KEGG: dvl:Dvul_1888 NADH dehydrogenase" /codon_start=1 /transl_table=11 /product="FAD-dependent pyridine nucleotide-disulphide oxidoreductase" /protein_id="ZP_05429560.1" /db_xref="GI:256004582" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR001327" /db_xref="InterPro:IPR007301" /db_xref="InterPro:IPR013027" /translation="MAHKVLILGAGYAGIEAALTLHKKKRKKDDIEITIIDKNPYHTL LTELHEVAGNRITEDAVIVPLKDIFAYTDVKIVKDEIKNIDLENNKLISDTNEYQYDY LIFAVGSEPNYYGIPGMEEYAFPLWSFKDAVAIREHIKDCFDKASRTTDPETRKTLLT FVVGGGGFTGVETIGEIAHWVKSLCREYNIKREEVDLKLIEALPKILSNLKDKNINKA MKYLTNTLKVDVLLNSAISKLNEDSVELKDGRKIPTKTLIWTAGVRACCLNDNLSLEK GRACRIKVDKYAATQFKNVYAVGDASCFEYNGHTLPALVEAALQTGKGAALNVLNDIR GKEREEIKPKLHGVMVSVGSFFAVAEIMGVLLPRFLAILMKYLVNIHYLFGIGGFELV FKYIRHEFFQKKQDKFLLEKHYSVTSPTFWLVPLRLFLGYSWLMEGLNKLKEGWLSTP MLAGMAVDGQTSASVTETGEKVFRIISSHTPSWYAFIAEKLVIPNALFFQWLIVLAEI GLGIAFISGTFTFLAGLGALALNINFLLSTGLYETSWWFIPAAICMLAGAGRSFGVDY YLIPYLMRQWRYFVRNQKIKLFLFR" misc_feature complement(42284..43486) /locus_tag="ClothDRAFT_1421" /note="NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252" /db_xref="CDD:31444" gene 43857..44948 /locus_tag="ClothDRAFT_1422" CDS 43857..44948 /locus_tag="ClothDRAFT_1422" /inference="protein motif:PFAM:PF02424" /note="PFAM: ApbE family lipoprotein; KEGG: scl:sce8631 putative thiamine biosynthesis lipoprotein ApbE" /codon_start=1 /transl_table=11 /product="ApbE family lipoprotein" /protein_id="ZP_05429561.1" /db_xref="GI:256004583" /db_xref="InterPro:IPR003374" /translation="MLVNKIWHCLLIGDYMTKRFTVIILSIVLCTSVLFVSCGYNSSD LYETQEFLMGTVVLQKIYHENAAEIAKEVNDRIAEIESTMTINKPGGEINLLNDAAGK EYVKLGEDTLYVLDKAKQYAEISNGAFDVTIGPLVKAWGVFTDNPRVPSKNEIDELLK LVNYKDINIDFENSTAMLAKEGQIVDLGGIAKGFAADEAVEIYKEHGVKSALISLGGN IFTLSGKPDGSPWMVGIRNPRGNDGSYIGIVRVKDKAVVSSGDYERFFEKDGVRYHHI LDPKTGYPADTGLIGTTIISDFSIDADALSTAVFVLGLEEGMKLVESLDGVDAVFITA DKKIYVTDGLKDTFIFKDESKEFEYVEKR" misc_feature 44088..44852 /locus_tag="ClothDRAFT_1422" /note="ApbE family; Region: ApbE; cl00643" /db_xref="CDD:186123" gene 44932..45312 /locus_tag="ClothDRAFT_1423" CDS 44932..45312 /locus_tag="ClothDRAFT_1423" /inference="protein motif:PFAM:PF07009" /note="PFAM: protein of unknown function DUF1312; KEGG: pca:Pcar_0036 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1312" /protein_id="ZP_05429562.1" /db_xref="GI:256004584" /db_xref="InterPro:IPR010739" /translation="MLKKGDFFILGFVLILIIVSFTGVYLYKNSGSNAHKIAVIIKDN EEIKRIDIDNVNEPLEISVSGEYNNIILVEKGRIRFKEADCPDRVCVNTGWLTGKGDT AVCLPNKTMIKIEGQSSDVDIVTY" misc_feature 45001..45291 /locus_tag="ClothDRAFT_1423" /note="Protein of unknown function (DUF1312); Region: DUF1312; cl02206" /db_xref="CDD:154798" gene 45393..45905 /locus_tag="ClothDRAFT_1424" CDS 45393..45905 /locus_tag="ClothDRAFT_1424" /inference="protein motif:PFAM:PF07456" /note="PFAM: Heptaprenyl diphosphate synthase component I; KEGG: pca:Pcar_0037 hypothetical protein" /codon_start=1 /transl_table=11 /product="Heptaprenyl diphosphate synthase component I" /protein_id="ZP_05429563.1" /db_xref="GI:256004585" /db_xref="InterPro:IPR010898" /translation="MNRVKKTVLLGLFVSQALILSIVESWIPIPSPVPGVKLGLANII TVITIIFFGFREAVSVVIARCVLSSIFGGGGWMLFLFSVTGGVLSSVVMSILYKSGRD KFSITGISIAGAVSHNVGQIFVAAVFMKDLAVAVVLPVLLVSGCIMGFFVGLVSSFLE GVLRKTRIFD" misc_feature 45429..45869 /locus_tag="ClothDRAFT_1424" /note="Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; cl01973" /db_xref="CDD:154687" gene 45934..46890 /locus_tag="ClothDRAFT_1425" CDS 45934..46890 /locus_tag="ClothDRAFT_1425" /EC_number="2.5.1.30" /inference="protein motif:PRIAM:2.5.1.30" /note="PFAM: Polyprenyl synthetase; KEGG: vfi:VF_0277 octaprenyl diphosphate synthase" /codon_start=1 /transl_table=11 /product="Trans-hexaprenyltranstransferase" /protein_id="ZP_05429564.1" /db_xref="GI:256004586" /db_xref="InterPro:IPR000092" /translation="MSSSYYPEIEKELVLLEEFIQKNIRSRNRLLNEAVSSIVKSGGK RLRPAFVILASQFGKYNRKKVIPAAAAIEILHTATLIHDDVVDRTKFRRGQVTISEKF GVDMAVYVGDYLYTKAVLLLAGNVPEKRLSILAKGIKAICEGEVDQYQHKYSIDTSVY TYLKRIGRKTAVLFSAACALGAYIAKCPQEVSRSLVKLGLYYGMAFQIKDDINNYTKA QYEEDKPVGNDILEGIITLPVILGLKLKPELREPLKNFLDKKGNVTEDEAARVVQLIK ESGGVEESRVFLNKYVEKALKEIQNLPDNEYKKAFERIIKAL" misc_feature 46009..46887 /locus_tag="ClothDRAFT_1425" /note="Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685" /db_xref="CDD:173833" misc_feature order(46156..46158,46165..46173,46177..46185,46189..46194, 46207..46212,46366..46368,46375..46377,46438..46443, 46450..46452,46561..46566,46573..46575,46603..46605, 46618..46620,46633..46635) /locus_tag="ClothDRAFT_1425" /note="substrate binding pocket; other site" /db_xref="CDD:173833" misc_feature 46165..46194 /locus_tag="ClothDRAFT_1425" /note="chain length determination region; other site" /db_xref="CDD:173833" misc_feature order(46180..46185,46192..46194,46207..46212,46375..46377, 46438..46440,46561..46566,46573..46575,46603..46605, 46618..46620,46633..46635) /locus_tag="ClothDRAFT_1425" /note="substrate-Mg2+ binding site; other site" /db_xref="CDD:173833" misc_feature order(46180..46185,46192..46194,46207..46212,46438..46440, 46561..46566) /locus_tag="ClothDRAFT_1425" /note="catalytic residues; other site" /db_xref="CDD:173833" misc_feature order(46180..46185,46192..46194,46207..46212,46375..46377, 46438..46440) /locus_tag="ClothDRAFT_1425" /note="aspartate-rich region 1; other site" /db_xref="CDD:173833" misc_feature order(46198..46242,46582..46587,46603..46620,46627..46641) /locus_tag="ClothDRAFT_1425" /note="active site lid residues" /db_xref="CDD:173833" misc_feature order(46561..46566,46573..46575,46603..46605,46618..46620, 46633..46635) /locus_tag="ClothDRAFT_1425" /note="aspartate-rich region 2; other site" /db_xref="CDD:173833" gene 46970..47389 /locus_tag="ClothDRAFT_1426" CDS 46970..47389 /locus_tag="ClothDRAFT_1426" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429565.1" /db_xref="GI:256004587" /translation="MLMIKVVCGKKGSGKTRALVDSANSFVSTALGDAVFIDGSSQLM CDLHHKVRFINVSEFPIDISSSCTFLGFLCGIISSNFDVKWVYMDDLIRIVRKPPHEM KELFDGFNELSEKFNVDFYVSIEGDPDSMPDFIKVCY" gene 47688..50135 /locus_tag="ClothDRAFT_1427" CDS 47688..50135 /locus_tag="ClothDRAFT_1427" /inference="protein motif:TFAM:TIGR00595" /note="KEGG: gur:Gura_0374 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein" /codon_start=1 /transl_table=11 /product="primosomal protein N'" /protein_id="ZP_05429566.1" /db_xref="GI:256004588" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR005259" /db_xref="InterPro:IPR006935" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014021" /translation="MNNIASIAISNTTRKFDKDYHYIIPDKYIGSIVPGMRVIVPFGK SNRLVEGYVLDVLESPEVSSLKEISRVIDEKPVLKENMIRLACWMKRQYICTYYDTIK CMLPPGTGVSSTKVVRLKKCEGGFKGNIKKIIDVLAECGGEMEYEELKKQVNTKTFAK YINNLKEQGCIEVHEEFTSKVKEKYVRAVYLAKPWEEVVYDIETNKIKNIKHIRILEL LAENEYIPVGDIVRFVGVSAGVLDTLKKKGYLEFEDIEVTRDPAANMPYERTLPMKPT QEQQVVIDRVKSMLDSGEFNEVLLHGITGSGKTEVYLQLIGHCISMGKQAIVLVPEIS LTPQMVNRFKGRFGEDVAVMHSRLSLGERYDQWRLVRDGRTKVVVGARSAVFAPFDNL GLVIIDEEHESSYKSEIVPKYHAAEIARQRCIMENAVLLYGSATPSVETYYRAKTGEI ELLEMTKRANNMLLPEVKVVDMRNELNAGNRSVFSRCLQNEIRKNIDSGQQTIVFLNR RGYATFILCRNCGYVLKCPYCDVSLTYHSHEERVICHYCGFTVKNPEHCPKCKSNHIR NFGTGTQKIEEEVKKQFEGCTVIRMDLDTTTGKNSHEEILRKFRDDNINVMVGTQMIA KGHDFPNVTLVGVLAADSILNTGDYKAAERTFQLLTQVAGRAGRGTIPGRVIIQTYNT DNYSIVCACEQDYVSFYNNEILVRKNLQYPPFIHLASVILSGVNDKQVLNRALFVKNE LCRHFKDNGSTAQILGPLRAPLAKIKNKYRWRIVIKCEESDKLIDVLTKVSDGYYSKS AKNSVALSVDINPVNML" misc_feature 47694..>48215 /locus_tag="ClothDRAFT_1427" /note="Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198" /db_xref="CDD:31391" misc_feature 48288..50129 /locus_tag="ClothDRAFT_1427" /note="primosome assembly protein PriA; Validated; Region: PRK05580" /db_xref="CDD:180144" misc_feature 48573..48998 /locus_tag="ClothDRAFT_1427" /note="DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046" /db_xref="CDD:28927" misc_feature 48600..48614 /locus_tag="ClothDRAFT_1427" /note="ATP binding site; other site" /db_xref="CDD:28927" misc_feature 48879..48890 /locus_tag="ClothDRAFT_1427" /note="putative Mg++ binding site; other site" /db_xref="CDD:28927" misc_feature 49404..49691 /locus_tag="ClothDRAFT_1427" /note="DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl12029" /db_xref="CDD:175389" gene 50182..50694 /locus_tag="ClothDRAFT_1428" CDS 50182..50694 /locus_tag="ClothDRAFT_1428" /EC_number="3.5.1.88" /inference="protein motif:TFAM:TIGR00079" /note="KEGG: ank:AnaeK_0762 peptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase" /codon_start=1 /transl_table=11 /product="peptide deformylase" /protein_id="ZP_05429567.1" /db_xref="GI:256004589" /db_xref="InterPro:IPR000181" /translation="MAVRFIREDGDEILRKVSKKVDVIDERIKTLLDDMAETMYAANG VGLAAPQVGVLKRVVVIDVGDGLMELINPEIVEQEGEQIDIEGCLSIPGVAGEVKRPA RVVVEALNREGEKITVEGKELLAVALCHEIDHLDGILFTDKVIRFIDEDEMERRRENK RRNKIRQNKG" misc_feature 50197..50601 /locus_tag="ClothDRAFT_1428" /note="Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(...; Region: Pep_deformylase; cd00487" /db_xref="CDD:29602" misc_feature order(50311..50319,50332..50334,50440..50448,50569..50574, 50581..50583) /locus_tag="ClothDRAFT_1428" /note="active site" /db_xref="CDD:29602" misc_feature order(50317..50319,50332..50334,50446..50448,50572..50574) /locus_tag="ClothDRAFT_1428" /note="catalytic residues; other site" /db_xref="CDD:29602" misc_feature order(50443..50445,50569..50571,50581..50583) /locus_tag="ClothDRAFT_1428" /note="metal-binding site" /db_xref="CDD:29602" gene 50768..51688 /locus_tag="ClothDRAFT_1429" CDS 50768..51688 /locus_tag="ClothDRAFT_1429" /inference="protein motif:TFAM:TIGR00460" /note="TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: pca:Pcar_0244 methionyl-tRNA formyltransferase" /codon_start=1 /transl_table=11 /product="methionyl-tRNA formyltransferase" /protein_id="ZP_05429568.1" /db_xref="GI:256004590" /db_xref="InterPro:IPR001555" /db_xref="InterPro:IPR002376" /db_xref="InterPro:IPR005793" /db_xref="InterPro:IPR005794" /translation="MGTPEFAIPSLEMLVREGYEVAAVVTQPDKPKGRGKKTAMPPVK EFAIKNNIEVLQPSKVKTPEFVSTIRELRPDLLVTAAYGKILPQEVLDIPPYGCVNVH GSLLPKYRGAAPINWAIINGEKVTGITTMYTDAGMDTGDMLLKAEIEISDDMTAGELH DKLACLGAEVLRETLKKIEDSTLQRIPQPHEQATYAPMLDKTVGCINWSKSARDVHNL VRGTNPWPVAFTYYKGQKMKVWVTSVLDEENHNFTPGTILKVGKDGLVVACGVGKVVI KEVQFDSSRRMTVEEYICGHKVGEGEVLGQ" misc_feature 50768..51682 /locus_tag="ClothDRAFT_1429" /note="methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005" /db_xref="CDD:178787" misc_feature 50825..51292 /locus_tag="ClothDRAFT_1429" /note="Formyl transferase; Region: Formyl_trans_N; cl00395" /db_xref="CDD:185966" misc_feature 51359..51658 /locus_tag="ClothDRAFT_1429" /note="Formyl transferase, C-terminal domain; Region: Formyl_trans_C; pfam02911" /db_xref="CDD:145851" gene 51663..52433 /locus_tag="ClothDRAFT_1430" CDS 51663..52433 /locus_tag="ClothDRAFT_1430" /inference="protein motif:PFAM:PF01976" /note="PFAM: protein of unknown function DUF116; KEGG: gur:Gura_0820 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF116" /protein_id="ZP_05429569.1" /db_xref="GI:256004591" /db_xref="InterPro:IPR002829" /translation="MKVKYLDNSYRNFASLMGTVLVLFVTILAAFGLLYSYSTINTYN FILLVLILITVIVTLFYFVSSIAIMYVYRRKKASRIVLCISRTGLRMLFPLVIVLTGL FGGNKDTIKKFYIDFNNLLVDTMDKKYSPDEIMILLPHCLQYSECEYKITNDINNCKR CGRCCIGFIADISAEKKVPAYVVTGGTAARNIVSKKEPKIIISVACERDLSSGIADVG RIPVIGIVNDRPNGPCYNTNVDVDAIRNKLESIINEKE" sig_peptide 51663..51755 /locus_tag="ClothDRAFT_1430" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.949) with cleavage site probability 0.323 at residue 31" misc_feature 51936..52409 /locus_tag="ClothDRAFT_1430" /note="Protein of unknown function DUF116; Region: DUF116; cl00800" /db_xref="CDD:154005" gene 52450..53133 /locus_tag="ClothDRAFT_1431" CDS 52450..53133 /locus_tag="ClothDRAFT_1431" /inference="protein motif:PFAM:PF04298" /note="PFAM: peptidase membrane zinc metallopeptidase putative; KEGG: tgr:Tgr7_3069 peptidase, membrane zinc metallopeptidase, putative" /codon_start=1 /transl_table=11 /product="peptidase membrane zinc metallopeptidase putative" /protein_id="ZP_05429570.1" /db_xref="GI:256004592" /db_xref="InterPro:IPR007395" /translation="MYGIDQYYIILVLPALILSIFAQFKVKSTFNKYSRVRNTSGMTG ADVARLILDRNGLSDVRIERVAGELTDHYDPRTRVIRLSQSVYGSNSVAAIGVAAHET GHAIQHSEQYGPLVLKRNLVPVANIGSCLGFPLAIAGLFFGLPFLVNLGIIFYSLAVA FYVITLPVEFNASSRAIRTLEDTGVLNYDEIDPAKKVLSAAALTYVAAAAVAIGNLLR LIMLTKRRD" misc_feature 52468..53127 /locus_tag="ClothDRAFT_1431" /note="Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; cl01049" /db_xref="CDD:154167" gene 53133..54500 /locus_tag="ClothDRAFT_1432" CDS 53133..54500 /locus_tag="ClothDRAFT_1432" /inference="protein motif:TFAM:TIGR00563" /note="TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: gme:Gmet_0066 Fmu, rRNA SAM-dependent methyltransferase:Nop2p" /codon_start=1 /transl_table=11 /product="sun protein" /protein_id="ZP_05429571.1" /db_xref="GI:256004593" /db_xref="InterPro:IPR001678" /db_xref="InterPro:IPR004573" /db_xref="InterPro:IPR006027" /translation="MDMRTKVDKVRETALKILYDINEKGAYSNISLNKYLNGQEFESI DRAFITDIVYGTLKWQYTIDYLIEKFSSVKIKKISPWIFNILRMGIYQLIYTDKIPFF AACNESVKLAAKYGHAASSKYVNAVLRNIARNKENLPYPDRNNDTAHYLSVKYSHPVW MVKDWLDCFGEEFTEGLLKANNEVAPFTVRVNDLKISKKELVDILTKDGFEVENGKYL DEALIIRNPSAVQKMDAFAKGYFQVQDESSMLVAKVLDPKPGETILDVCSAPGGKSTH IAQIMKNRGTVISRDIHEHKIKLIEQAKERLGLEIIKTEVFDAAVLDGKLIEKIDRVL VDAPCTGFGIIRRKPDIKWSKNSEDKAEIVSLQHKILSTASKYVKDGGVLVYSTCTLE PEENEKAVERFIEENKDFYLEDITEFLPDALRKESAGKGYIQLYPNIDGIDGFFIARM RKRSK" misc_feature 53148..54494 /locus_tag="ClothDRAFT_1432" /note="16S rRNA methyltransferase B; Provisional; Region: PRK14902" /db_xref="CDD:184895" misc_feature 53160..53531 /locus_tag="ClothDRAFT_1432" /note="RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the rRNA-...; Region: NusB_Sun; cl00223" /db_xref="CDD:185841" misc_feature 53160..53165 /locus_tag="ClothDRAFT_1432" /note="putative RNA binding site; other site" /db_xref="CDD:29564" misc_feature 53697..54488 /locus_tag="ClothDRAFT_1432" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene 54502..55551 /locus_tag="ClothDRAFT_1433" CDS 54502..55551 /locus_tag="ClothDRAFT_1433" /inference="protein motif:TFAM:TIGR00048" /note="TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein; KEGG: nis:NIS_0057 hypothetical protein" /codon_start=1 /transl_table=11 /product="radical SAM enzyme, Cfr family" /protein_id="ZP_05429572.1" /db_xref="GI:256004594" /db_xref="InterPro:IPR004383" /db_xref="InterPro:IPR007197" /translation="MDAKADLLSMTIEELENLMAEMGEQKFRAKQIFQWTNKGIKDID AMTNLSKDLREKLKERAYINRLEVIKKFVSKIDGTIKYLFKLNDGNIIESVLMQYLHG YSACISSQVGCKMGCKFCASTGVGFVRNLTPGEMLDQILTIQNDTKNRIGNVVIMGIG EPLDNYENVVKFLRLVNHKDGINLGARHISVSTCGLVPEILRLAEEKIPVTLSISLHA PNDEIREKIMPINKRYSIDKIIEACKIYTETTNRRITFEYAMIDGLNDSKENALELAK RIRGMLCHVNLIPVNTVSDTGFKRSSREKITAFKEILERFGVETTVRRELGSDINAAC GQLRRNLVENGQLVY" misc_feature 54511..55521 /locus_tag="ClothDRAFT_1433" /note="Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820" /db_xref="CDD:31162" misc_feature 54835..55341 /locus_tag="ClothDRAFT_1433" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(54838..54840,54844..54846,54850..54852,54856..54861, 54973..54975,54979..54984,55069..55077,55144..55146, 55270..55272) /locus_tag="ClothDRAFT_1433" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene 55616..56353 /locus_tag="ClothDRAFT_1434" CDS 55616..56353 /locus_tag="ClothDRAFT_1434" /EC_number="3.1.3.16" /inference="protein motif:PRIAM:3.1.3.16" /note="KEGG: scl:sce6484 phosphoprotein phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein" /codon_start=1 /transl_table=11 /product="protein serine/threonine phosphatase" /protein_id="ZP_05429573.1" /db_xref="GI:256004595" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR014045" /translation="MRFAAKSDRGIVRELNEDNYKLITGYEDVPDVFVVADGMGGHSS GELASSMAVEFAEKYILEHRELFSSEESVLSTIKELMEEANTVIFNRAAESQLNFGMG TTFITAVMLKDKMYVGHVGDSRVYLIRDGKIEKVTTDHSYIEELIKNGSLTREEAENH PNKNIITRALGCEENILIDTITVDVKEKDIFVLCTDGLTNMLKEDEILDVIMKNDDPE VSCSELVRLANEKGGEDNITVIVVIND" misc_feature 55619..56341 /locus_tag="ClothDRAFT_1434" /note="Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143" /db_xref="CDD:29062" misc_feature order(55652..55654,55664..55669,55724..55732,56201..56203, 56318..56320) /locus_tag="ClothDRAFT_1434" /note="active site" /db_xref="CDD:29062" gene 56424..58535 /locus_tag="ClothDRAFT_1435" CDS 56424..58535 /locus_tag="ClothDRAFT_1435" /inference="protein motif:PFAM:PF00069" /note="PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: azo:azo3774 putative serine/threonine protein kinase" /codon_start=1 /transl_table=11 /product="serine/threonine protein kinase with PASTA sensor(s)" /protein_id="ZP_05429574.1" /db_xref="GI:256004596" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR001245" /db_xref="InterPro:IPR002290" /db_xref="InterPro:IPR005543" /db_xref="InterPro:IPR008271" /db_xref="InterPro:IPR017441" /db_xref="InterPro:IPR017442" /translation="MVGQILGNRYELIEKIGGGGMADVYKARCKLLNRFVAIKILKPE FINDEEFLKRFTIEAQAAASLSHPNIVSIYDVGQENDIHYIVMEYVNGQTLKEYLDEN GALYWKDAVNIAIQICQAIEHAHKNHVVHRDIKPHNILLTKDGMLKVTDFGIARAVSS STITMAGNAIGSVHYFSPEQARGGFTDEKSDLYSLGIVLYELLTGRVPFDGESPVAVA IKHIQDEPEEPINIKEDIPTGVNSIVMRAIQKDQALRYQSASELLNDLYKVLKQPDAQ FAKARTTEDSPTVRIPSIKKKELVLEMDTSGKAGDDAVKKKKKDNKTTVWAVVTSILV IFVLGALMVKGLGPVVYSMFNKPEDFIVEDYTNQNFYEVKGKLSQYNIEAIEIRKHDD QIPKDRIISQDKAVGERIKPGEFAKIEFVVSDGPLLVKIPDLRRMEYRQAVIELRQLG LEANVIDEYSDVVSKGVVIRTEPDINAEVKPGTVVNVYKSLGPEIKYSLVPNLIGKTK SEALNLLVGAKLTMGKIYPEDMTYARDKIVRQEPAAGTEVEEGTPVNIYLEDYNPDQK YVTRLIELDNPDNYGENIKFLVNITRSDTKRVETLYSEVRKKSDFPITISIPVPNGGS TLVRVYLDNKNYMEFTEEFNKRSNETNTGNTANNNGNSNNNGSGSGTDNINDTNNTDN ANNDNERTEESGETNHAEAAG" misc_feature 56448..57215 /locus_tag="ClothDRAFT_1435" /note="Protein Kinases, catalytic domain; Region: PKc_like; cl09925" /db_xref="CDD:186871" misc_feature order(56469..56483,56493..56495,56532..56534,56538..56540, 56634..56636,56682..56693,56703..56705,56820..56822, 56826..56828,56832..56837,56841..56843,56874..56876, 56883..56885,56934..56945) /locus_tag="ClothDRAFT_1435" /note="active site" /db_xref="CDD:173623" misc_feature order(56469..56483,56493..56495,56532..56534,56538..56540, 56634..56636,56682..56693,56703..56705,56820..56822, 56826..56828,56832..56837,56841..56843,56874..56876) /locus_tag="ClothDRAFT_1435" /note="ATP binding site; other site" /db_xref="CDD:173623" misc_feature 56481..57218 /locus_tag="ClothDRAFT_1435" /note="Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220" /db_xref="CDD:128516" misc_feature order(56481..56483,56703..56705,56820..56822,56826..56828, 56832..56834,56883..56885,56934..56945) /locus_tag="ClothDRAFT_1435" /note="substrate binding site; other site" /db_xref="CDD:173623" misc_feature order(56871..56891,56934..56945) /locus_tag="ClothDRAFT_1435" /note="activation loop (A-loop); other site" /db_xref="CDD:173623" misc_feature 57405..58325 /locus_tag="ClothDRAFT_1435" /note="Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815" /db_xref="CDD:32644" misc_feature 57489..57695 /locus_tag="ClothDRAFT_1435" /note="PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768" /db_xref="CDD:141692" misc_feature 57711..57893 /locus_tag="ClothDRAFT_1435" /note="PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis...; Region: PASTA_pknB; cd06577" /db_xref="CDD:119328" misc_feature 57921..58097 /locus_tag="ClothDRAFT_1435" /note="PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis...; Region: PASTA_pknB; cd06577" /db_xref="CDD:119328" gene 58555..59439 /locus_tag="ClothDRAFT_1436" CDS 58555..59439 /locus_tag="ClothDRAFT_1436" /inference="protein motif:TFAM:TIGR00157" /note="TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; KEGG: shl:Shal_3642 ribosome-associated GTPase" /codon_start=1 /transl_table=11 /product="ribosome small subunit-dependent GTPase A" /protein_id="ZP_05429575.1" /db_xref="GI:256004597" /db_xref="InterPro:IPR004881" /db_xref="InterPro:IPR010914" /translation="MPSGIIIKGIGGFYYVKTENGIYECKARGVFRKDSKIPLPGDEV VISVIDEEKKKGYIEEICERKIQLIRPAVANINQIALVVSVKSPLPDFVLLDKLLITV MQKELNAIICINKIDLDEGYKDVIIDCYKGTGVETVCVSSVLNVGFEQLAKMLEGKTT VFAGQSGVGKSTILNKILDSYVMETGEISDKIERGRHTTRHAELLELKSGGFVVDTPG FSSFELSEIEPKELQNYYPEFRDYIGKCRFAGCSHISEPGCMVKSALENGMINKDRYG RYIIFYNMLKDKQRRKYS" misc_feature 58591..59427 /locus_tag="ClothDRAFT_1436" /note="GTPase RsgA; Reviewed; Region: PRK00098" /db_xref="CDD:178861" misc_feature 58591..59400 /locus_tag="ClothDRAFT_1436" /note="YjeQ/EngC. YjeQ (YloQ in Bacillus subtilis) represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence...; Region: YjeQ_engC; cd01854" /db_xref="CDD:57925" misc_feature order(58672..58683,58753..58755,58774..58779,59155..59157, 59161..59166,59170..59172) /locus_tag="ClothDRAFT_1436" /note="GTPase/OB domain interface; other site" /db_xref="CDD:57925" misc_feature order(58828..58833,58840..58845,58849..58854,58861..58866, 58957..58959,59245..59247,59257..59259,59263..59265, 59374..59376,59383..59385,59395..59397) /locus_tag="ClothDRAFT_1436" /note="GTPase/Zn-binding domain interface; other site" /db_xref="CDD:57925" misc_feature order(58894..58899,58903..58908,58975..58980,59053..59070) /locus_tag="ClothDRAFT_1436" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:57925" misc_feature 58894..58905 /locus_tag="ClothDRAFT_1436" /note="G4 box; other site" /db_xref="CDD:57925" misc_feature 58975..58983 /locus_tag="ClothDRAFT_1436" /note="G5 box; other site" /db_xref="CDD:57925" misc_feature 59044..59067 /locus_tag="ClothDRAFT_1436" /note="G1 box; other site" /db_xref="CDD:57925" misc_feature 59140..59163 /locus_tag="ClothDRAFT_1436" /note="Switch I region; other site" /db_xref="CDD:57925" misc_feature 59149..59151 /locus_tag="ClothDRAFT_1436" /note="G2 box; other site" /db_xref="CDD:57925" misc_feature 59197..59208 /locus_tag="ClothDRAFT_1436" /note="G3 box; other site" /db_xref="CDD:57925" misc_feature 59203..59211 /locus_tag="ClothDRAFT_1436" /note="Switch II region; other site" /db_xref="CDD:57925" gene 59598..60260 /locus_tag="ClothDRAFT_1437" CDS 59598..60260 /locus_tag="ClothDRAFT_1437" /EC_number="5.1.3.1" /inference="protein motif:TFAM:TIGR01163" /note="KEGG: gme:Gmet_0067 ribulose-5-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase" /codon_start=1 /transl_table=11 /product="ribulose-phosphate 3-epimerase" /protein_id="ZP_05429576.1" /db_xref="GI:256004598" /db_xref="InterPro:IPR000056" /translation="MLIKIAPSILSADFSKLGEEVLRIEKAGADLVHIDVMDGHFVPN ITIGPPVVKSLKKVSKLPFDVHLMIENPDMYIESFADAGADIISVHAEACRHLHRTIQ KIKQLGIKAAVALNPATPLCAVEWVMEDVDMILLMTVNPGFGGQKYINGVTRKIEELE RIVESRGLNIDIEVDGGIDTETVQYVTKAGANVIVSGSTIFAAEDTAKIIQELRMNSY RK" misc_feature 59607..60239 /locus_tag="ClothDRAFT_1437" /note="Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative...; Region: RPE; cd00429" /db_xref="CDD:73366" misc_feature 59610..60239 /locus_tag="ClothDRAFT_1437" /note="ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163" /db_xref="CDD:130231" misc_feature order(59619..59621,59625..59627,59700..59702,59799..59801, 60018..60023,60027..60032,60120..60122,60126..60128, 60186..60191) /locus_tag="ClothDRAFT_1437" /note="substrate binding site; other site" /db_xref="CDD:73366" misc_feature order(59640..59642,59649..59651,59709..59711,59715..59720, 59724..59726,59730..59741,59808..59810,59820..59822, 59883..59885,59889..59894,59946..59948,59955..59957, 59961..59963,59973..59975,60015..60017,60042..60044, 60048..60050,60060..60062) /locus_tag="ClothDRAFT_1437" /note="hexamer interface; other site" /db_xref="CDD:73366" misc_feature order(59694..59696,59700..59702,59793..59795,60120..60122) /locus_tag="ClothDRAFT_1437" /note="metal-binding site" /db_xref="CDD:73366" gene 60273..60911 /locus_tag="ClothDRAFT_1438" CDS 60273..60911 /locus_tag="ClothDRAFT_1438" /inference="protein motif:TFAM:TIGR01378" /note="TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: dat:HRM2_18060 ThiN" /codon_start=1 /transl_table=11 /product="thiamine pyrophosphokinase" /protein_id="ZP_05429577.1" /db_xref="GI:256004599" /db_xref="InterPro:IPR006282" /db_xref="InterPro:IPR007371" /translation="MMYALVVCNGSIIDYSFYRKFFDEADFIVCADGGALHLQRLGIK PDVLLGDFDSIESEHLEYYMKQNVEILKFPAEKDMTDTELAVNTAIDRGYKNIVIIGG TGTRLDHTLSNIFLLKLMLDRGVKGRIINEYNEMFLINDSTEIEAEDGCYLTLLPLTS KVEGITTEGLYYPLRGEAIEMGSTRGVSNCFVEKKARISITSGILIAIKTRE" misc_feature 60282..60902 /locus_tag="ClothDRAFT_1438" /note="Thiamine pyrophosphokinase; Region: TPK; cd07995" /db_xref="CDD:153431" misc_feature 60291..60896 /locus_tag="ClothDRAFT_1438" /note="thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378" /db_xref="CDD:162328" misc_feature order(60294..60302,60363..60371,60423..60425,60429..60434, 60501..60518,60576..60578,60582..60590,60597..60599, 60609..60611,60786..60788,60792..60794,60828..60839) /locus_tag="ClothDRAFT_1438" /note="active site" /db_xref="CDD:153431" misc_feature order(60369..60371,60381..60383,60390..60392,60501..60509, 60519..60521,60579..60581,60585..60608,60612..60617, 60672..60674,60678..60680,60726..60728,60732..60734, 60738..60740,60744..60749,60825..60827,60831..60836, 60894..60896) /locus_tag="ClothDRAFT_1438" /note="dimerization interface; other site" /db_xref="CDD:153431" misc_feature order(60423..60425,60501..60512,60786..60788,60792..60794, 60828..60839) /locus_tag="ClothDRAFT_1438" /note="thiamine binding site; other site" /db_xref="CDD:153431" gene complement(61050..63260) /locus_tag="ClothDRAFT_1439" CDS complement(61050..63260) /locus_tag="ClothDRAFT_1439" /inference="protein motif:PFAM:PF00759" /note="PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; cellulosome protein dockerin type I; KEGG: hch:HCH_02464 cellulase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 9" /protein_id="ZP_05429578.1" /db_xref="GI:256004600" /db_xref="InterPro:IPR001701" /db_xref="InterPro:IPR001956" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MKKLIITVIVSAVLLTALIPQLPVFAADYNYGEALQKAIMFYEF QMSGKLPDNIRNNWRGDSCLGDGSDVGLDLTGGWFDAGDHVKFNLPMAYTATMLAWAV YEYKDALQKSGQLGYLMDQIKWASDYFIRCHPEKYVYYYQVGNGDMDHRWWVPAECID VQAPRPSYKVDLSNPGSTVTAGTAAALAATALVFKDTDPAYAALCIRHAKELFDFAET TMSDKGYTAALNFYTSHSGWYDELSWAGAWIYLADGDETYLEKAEKYVDKWPIESQTT YIAYSWGHCWDDVHYGAALLLAKITNKSLYKEAIERHLDYWTVGFNGQRVRYTPKGLA HLTDWGVLRHATTTAFLACVYSDWSECPREKANIYIDFAKKQADYALGSSGRSYVVGF GVNPPQHPHHRTAHSSWCDSQKVPEYHRHVLYGALVGGPDASDAYVDDIGNYVTNEVA CDYNAGFVGLLAKMYEKYGGNPIPNFMAIEEKTNEEIYVEATANSNNGVELKTYLYNK SGWPARVCDKLSFRYFMDLTEYVSAGYNPNDITVSIIYSAAPTAKISKPILYDASKNI YYCEIDLSGTKIFPGSNSDHQKETQFRIQPPAGAPWDNTNDFSYQGIKKNGEVVKEMP VYEDGVLIFGVEPNGTGPATPTPKPSVNPSPSPTPTSDILYGDINLDGKINSSDVTLL KRYIVKSIDVFPTADPERSLIASDVNGDGRVNSTDYSYLKRYVLKIIPTIPGNS" sig_peptide complement(63180..63260) /locus_tag="ClothDRAFT_1439" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 27" misc_feature complement(61863..63251) /locus_tag="ClothDRAFT_1439" /note="endoglucanase; Region: PLN02420" /db_xref="CDD:178040" misc_feature complement(61875..63173) /locus_tag="ClothDRAFT_1439" /note="Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959" /db_xref="CDD:186543" misc_feature complement(61545..61802) /locus_tag="ClothDRAFT_1439" /note="Cellulose binding domain; Region: CBM_3; pfam00942" /db_xref="CDD:109977" misc_feature complement(61203..61262) /locus_tag="ClothDRAFT_1439" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature complement(61083..61145) /locus_tag="ClothDRAFT_1439" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 63814..64335 /locus_tag="ClothDRAFT_1440" CDS 63814..64335 /locus_tag="ClothDRAFT_1440" /inference="protein motif:PFAM:PF00881" /note="PFAM: nitroreductase; KEGG: pca:Pcar_1624 nitroreductase" /codon_start=1 /transl_table=11 /product="nitroreductase" /protein_id="ZP_05429579.1" /db_xref="GI:256004601" /db_xref="InterPro:IPR000415" /translation="MLYDLLKSRRSIRKFQNKEVEKEKIDIILKSALMAPSSRSRRPW EFIAVTDKEKLEKLSKIREHSSDFLAGAPLGIVVVANPKTCDVWIEDSSIAAIIIQLS AQSLGLGSCWIQVRERFGRNNKRAGDIVKEILQIPDEYEVECIIAVGYSAEEKKPYNV DELPYNKLHFESF" misc_feature 63817..64302 /locus_tag="ClothDRAFT_1440" /note="NAD(P)H:flavin oxidoreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes...; Region: NADPH_oxidoreductase_2; cd02151" /db_xref="CDD:48396" misc_feature order(63838..63840,63844..63846,63850..63852,63928..63930, 64153..64158) /locus_tag="ClothDRAFT_1440" /note="putative FMN binding site; other site" /db_xref="CDD:48396" gene complement(64402..65595) /locus_tag="ClothDRAFT_1441" CDS complement(64402..65595) /locus_tag="ClothDRAFT_1441" /inference="protein motif:PFAM:PF00155" /note="PFAM: aminotransferase class I and II; KEGG: gme:Gmet_0732 aspartate aminotransferase" /codon_start=1 /transl_table=11 /product="aminotransferase class I and II" /protein_id="ZP_05429580.1" /db_xref="GI:256004602" /db_xref="InterPro:IPR001176" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /translation="MISESVVNSLKKASWIRAMFEEGEKLRKIHGADNVYDFTLGNPD HEPPSSVKETLKKIVTEDKPGIHRYMNNAGYEDVRQKVADYLNRTSGLSSISSQHIIM TCGAAGALNVVLKTLLNPGEEVIILAPYFAEYIFYVGNHGGKVVIVPPEKDSFKPDLK ILENSITEKTKAIIINSPNNPSGYIYSEETLKEIFEVLEKKEKEYNSSIYAISDEPYY KLVYDNVKLPFLFRLYKKSFIVNSFSKSLALAGERIGYIAVNPEIPELELILESLIFC NRTLGYVNAPALFQKAIADSLDADIDVESYKQRRDLIYDTLTRLGFSCIKPQGTFYIF PKSPIEDDIQFIKHAVKYNILLVPGTGFGLPGHFRLSYCVSMDTIKKSLPAFEALAKD FNLIK" misc_feature complement(64411..65595) /locus_tag="ClothDRAFT_1441" /note="aspartate aminotransferase; Provisional; Region: PRK06836" /db_xref="CDD:180720" misc_feature complement(64423..65490) /locus_tag="ClothDRAFT_1441" /note="Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609" /db_xref="CDD:99734" misc_feature complement(order(64837..64839,64861..64866,64870..64872, 64945..64947,65056..65058,65203..65205,65275..65283)) /locus_tag="ClothDRAFT_1441" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99734" misc_feature complement(order(64720..64722,64729..64731,64837..64845, 64966..64968,65173..65175,65272..65274)) /locus_tag="ClothDRAFT_1441" /note="homodimer interface; other site" /db_xref="CDD:99734" misc_feature complement(64861..64863) /locus_tag="ClothDRAFT_1441" /note="catalytic residue; other site" /db_xref="CDD:99734" gene complement(65609..66601) /locus_tag="ClothDRAFT_1442" CDS complement(65609..66601) /locus_tag="ClothDRAFT_1442" /inference="protein motif:PFAM:PF05670" /note="PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; KEGG: pca:Pcar_1454 RNA-binding protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF814" /protein_id="ZP_05429581.1" /db_xref="GI:256004603" /db_xref="InterPro:IPR008532" /db_xref="InterPro:IPR008616" /translation="MTGKKAVDFHSLEIKQYNTVDFYPSISRVLDLFYTIKDTSERLA QKKADLAKILNNCIDRCNKKISIHMDTLREVAEREKFKLYGELITANIYCIPKNASKV SLLNYYSENGEYVEVPLDENLLPQENAQRYFKKYAKAKAAYIHATQQLEEARGELSYL ESVLHSLENSNSFEDIDDIRQELAEQGYLPSKKKRPEKKNSKNFTPYTYKSTDGFYIY VGKNNVQNDFLTLKFASSNDIWLHTKNIPGSHVIIRKDRGEIPDSTLFQAAMLAAYHS KAKNSSHVEVDYTKVKNVKKPNGAKPGMVIYDNYKTIIVTPDENVVNNLRMENR" misc_feature complement(65615..>66535) /locus_tag="ClothDRAFT_1442" /note="Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293" /db_xref="CDD:31484" misc_feature complement(65714..65971) /locus_tag="ClothDRAFT_1442" /note="Domain of unknown function (DUF814); Region: DUF814; pfam05670" /db_xref="CDD:114396" gene complement(66549..67376) /locus_tag="ClothDRAFT_1443" CDS complement(66549..67376) /locus_tag="ClothDRAFT_1443" /inference="protein motif:PFAM:PF05833" /note="PFAM: Fibronectin-binding A domain protein; KEGG: pca:Pcar_1454 RNA-binding protein" /codon_start=1 /transl_table=11 /product="Fibronectin-binding A domain protein" /protein_id="ZP_05429582.1" /db_xref="GI:256004604" /db_xref="InterPro:IPR008616" /translation="MPFDGIVTKNIVSELSDILTGARIEKIYQPEPDEIIINLRTKGQ NLKLLLSANASYPRIHLTDVTKENPINPPVFCMLLRKHLSGGKITKIDFHDFERVVTI HIETIDELGDLTFKKLVVEIMGKHSNIILVNNENKIIDSIKHVDSDISRVREVMPARP YTLPPGQDKINPLELDIDLLFSKAKEQGDPRISKFFLNNIKGFSPLLCEEICHRADVD PRLPVSSLSEDTIQNLKKVLKEIISKIENSEFTPCIIWNGDDRQKSRRFPFFGNKTI" misc_feature complement(<66612..67367) /locus_tag="ClothDRAFT_1443" /note="Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833" /db_xref="CDD:147794" gene complement(67633..69396) /locus_tag="ClothDRAFT_1444" CDS complement(67633..69396) /locus_tag="ClothDRAFT_1444" /inference="protein motif:TFAM:TIGR00229" /note="KEGG: dal:Dalk_2282 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein" /codon_start=1 /transl_table=11 /product="PAS/PAC sensor signal transduction histidine kinase" /protein_id="ZP_05429583.1" /db_xref="GI:256004605" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR000700" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013767" /translation="MRKNLHINENLPEDILESIVISSTEYAIIATDIHNRIIIWNKGA ELIYGYSKEEMLGKQFPPDLHRKGLPNNEFLFVPNNETKSRLIDQTMYAKRKDGTFIP ISITSTPRVNKNNKTLGLLILTRDITRYKLLDQFNSVLIEITHLINSSSSIDQMCSEV CNAISSFLGLPAVFICLFDRPGNFFYINAMTGLCKNCTGHTCGYHTCAKDVAENIKGC FKTYTQLTINHSPLSEHAIYEYMEAHLPGRGENFIIHIPLISDVSIMGILHIVVSEPQ KTFLLKESQILSLVANEITTGIQRKRLIEEIKEYADNLEKMVKERTRELREKDAQLVQ SEKLATLGEMATGIAHEINQPLGGISLITQGLILAKKRNKLTDEMLLEKLNAIIEQVD RIDKIIGHLRTFARQSDQTKTPVNIKMPLTDVFKLIGEQLKRQQISVDMDIEENLPYV LADHNRLEQVFLNLIINAKDALNEREKVQQRLVSENDADGQIVPPDKKITIKAFSDNK HVIIEITDNGIGISKSIINKIFEPFFTTKEVGKGTGIGLSISYGIVKEFNGTIEVESE EMKGSKFIIKFPIYKENSMQK" misc_feature complement(69013..69360) /locus_tag="ClothDRAFT_1444" /note="PAS domain S-box; Region: sensory_box; TIGR00229" /db_xref="CDD:161776" misc_feature complement(69016..69318) /locus_tag="ClothDRAFT_1444" /note="PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130" /db_xref="CDD:29035" misc_feature complement(order(69103..69105,69118..69120,69199..69210, 69247..69249,69265..69267,69277..69279)) /locus_tag="ClothDRAFT_1444" /note="putative active site; other site" /db_xref="CDD:29035" misc_feature complement(order(69076..69078,69082..69084,69166..69171, 69181..69183,69205..69207,69217..69219)) /locus_tag="ClothDRAFT_1444" /note="heme pocket; other site" /db_xref="CDD:29035" misc_feature complement(68464..68979) /locus_tag="ClothDRAFT_1444" /note="GAF domain; Region: GAF; cl00853" /db_xref="CDD:154040" misc_feature complement(68179..68385) /locus_tag="ClothDRAFT_1444" /note="Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-...; Region: HisKA; cd00082" /db_xref="CDD:119399" misc_feature complement(order(68194..68196,68206..68208,68215..68217, 68227..68229,68236..68238,68248..68250,68311..68313, 68320..68322,68332..68334,68341..68343,68353..68355, 68365..68367)) /locus_tag="ClothDRAFT_1444" /note="dimer interface; other site" /db_xref="CDD:119399" misc_feature complement(68347..68349) /locus_tag="ClothDRAFT_1444" /note="phosphorylation site" /db_xref="CDD:119399" misc_feature complement(67666..68028) /locus_tag="ClothDRAFT_1444" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature complement(order(67678..67680,67684..67689,67702..67704, 67708..67710,67756..67767,67834..67839,67843..67845, 67849..67851,67855..67857,67987..67989,67996..67998, 68008..68010)) /locus_tag="ClothDRAFT_1444" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature complement(67996..67998) /locus_tag="ClothDRAFT_1444" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature complement(order(67759..67761,67765..67767,67837..67839, 67843..67845)) /locus_tag="ClothDRAFT_1444" /note="G-X-G motif; other site" /db_xref="CDD:28956" gene complement(69424..70608) /locus_tag="ClothDRAFT_1445" CDS complement(69424..70608) /locus_tag="ClothDRAFT_1445" /inference="protein motif:PFAM:PF07228" /note="PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; KEGG: psb:Psyr_1912 response regulator receiver:stage II sporulation E" /codon_start=1 /transl_table=11 /product="response regulator receiver protein" /protein_id="ZP_05429584.1" /db_xref="GI:256004606" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR010822" /translation="MAKILVIDDESTILQNIKFLLEIDGNEVLTASSSTEGLRIFTEN CNSIDVVITDMKMPKLSGMDILREIKKITPHMAVIILTGHGDLDNAILAMKEGAFEYL RKPVTAQDLSIAINNAINRKKLLMENERMTQELLAHRNYLQGLHDSAAKILLNMLPKN LPDIEGFNFAVDYKSCDGVGGDMYDVCDIGDYICFYVFDVSHHGILAAVISIIIKSFL QNIEYNYRQGINKRRFPEIVLDLNLELLSNTAQNVFASLFLGFIDKNSKKLYTVSAGH IPQYIMKENGLVPLESTGPILGVFEDSTYKCAVNQLEPGDKVLLFTDGIIESPSDSSD ESSDGNQIFGYENMVKVLESCKNEPISTTIDKIMKAVKDFSGNRCTDDMTILGVEVLK EN" misc_feature complement(70252..70596) /locus_tag="ClothDRAFT_1445" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature complement(order(70294..70299,70306..70308,70363..70365, 70423..70425,70447..70449,70582..70587)) /locus_tag="ClothDRAFT_1445" /note="active site" /db_xref="CDD:29071" misc_feature complement(70447..70449) /locus_tag="ClothDRAFT_1445" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature complement(order(70423..70431,70435..70440)) /locus_tag="ClothDRAFT_1445" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature complement(70291..70299) /locus_tag="ClothDRAFT_1445" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature complement(69439..70041) /locus_tag="ClothDRAFT_1445" /note="Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120" /db_xref="CDD:185796" gene 70738..71028 /locus_tag="ClothDRAFT_1446" CDS 70738..71028 /locus_tag="ClothDRAFT_1446" /inference="protein motif:PFAM:PF04456" /note="PFAM: protein of unknown function DUF503; KEGG: dal:Dalk_4739 protein of unknown function DUF503" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF503" /protein_id="ZP_05429585.1" /db_xref="GI:256004607" /db_xref="InterPro:IPR007546" /translation="MVVGVCRVILNINEAFSLKEKRQVVKSIVERVKSRFNASVAEVG FNDKWKNAIIGISCVSNEAGHTDSMMANIVNFIENDGRVELVDYSTENIYVD" misc_feature 70741..71010 /locus_tag="ClothDRAFT_1446" /note="Protein of unknown function (DUF503); Region: DUF503; cl00669" /db_xref="CDD:153924" gene 71123..71198 /locus_tag="ClothDRAFT_R0029" /note="tRNA-Ala1" tRNA 71123..71198 /locus_tag="ClothDRAFT_R0029" /product="tRNA-Ala" gene 71753..71920 /locus_tag="ClothDRAFT_1447" CDS 71753..71920 /locus_tag="ClothDRAFT_1447" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429586.1" /db_xref="GI:256004608" /translation="MQVLWGLYRTYEELKLLQEVSKGNKGDSLYRTYEELKLLRIWLG IYTFDGFVSYL" gene 71898..72053 /locus_tag="ClothDRAFT_1448" CDS 71898..72053 /locus_tag="ClothDRAFT_1448" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429587.1" /db_xref="GI:256004609" /translation="MGLYRTYEELKLLDAIRRGALDFGLYRTYEELKHNDIYGTVVVI DEFVSYL" gene 73573..73665 /locus_tag="ClothDRAFT_1449" CDS 73573..73665 /locus_tag="ClothDRAFT_1449" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429588.1" /db_xref="GI:256004610" /translation="MYRTYEELKLASQVMPFDTGTMVCIVPMRN" gene 74279..74371 /locus_tag="ClothDRAFT_1450" CDS 74279..74371 /locus_tag="ClothDRAFT_1450" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429589.1" /db_xref="GI:256004611" /translation="MTKSEIAKILAGLYRTYEELKLAHTTYHGG" gene 74447..74551 /locus_tag="ClothDRAFT_1451" CDS 74447..74551 /locus_tag="ClothDRAFT_1451" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429590.1" /db_xref="GI:256004612" /translation="MYRTYEELKLADTTSAGISSGGLYRTYEELKLSL" gene 75252..>76023 /locus_tag="ClothDRAFT_1452" CDS 75252..>76023 /locus_tag="ClothDRAFT_1452" /inference="protein motif:PFAM:PF01978" /note="PFAM: transcriptional regulator TrmB; KEGG: dal:Dalk_4181 hypothetical protein" /codon_start=1 /transl_table=11 /product="transcriptional regulator, TrmB" /protein_id="ZP_05429591.1" /db_xref="GI:256004613" /db_xref="InterPro:IPR002831" /translation="MESMKGKVIRDIRNQEAKRKQLQKEIFNQRYNATKEAKFIDKED INMNSFRAIPKSVIQELGLSKAALAIYPVLCAKADFEKNNSFPISQKNIARFAGVSEN SVRNALKELENAGLLTKEKVTDGPRHFYVYKVTFYRRPELEANEQRGDAIYFYNCIID NGIWAELKPRTKVLYLTLRAVAKQDIELYSVIEGENYGGDWNGVNYDDYIRNRKWDVC DISLSKLCKLAKIERTNLTPILEELERYKLIERVGEWTK" ORIGIN 1 attattaaaa gaaagtgagg ttacttatat acctaatact aattggtcca tattaagtag 61 tcaacaactt ggcagatatg ctgaatatta ttcgaaaatg gaatttgcct cttatggatt 121 tgaagtatat acatcagaag tagatgatca tggaatagat ttcatcgcta aaacgaaatc 181 tggtgttttc cttgaaattc aggtgaaatc aattcgtaaa ctgagctatg tatttgtaca 241 aaaagaaaaa tggaatattg agagccccaa tacatattta gcactgttaa tatttgaaga 301 tggcaagttt cctgaatctt acctgattcc ggcaacggca tggaaaaccc ctaatgaatt 361 attttgtgac agggattatg ttggcttgaa aagcaagctg gaatatgggc tgaatatttc 421 aaagaaaaat atgaaattgc tgcaggagta taaaatggaa gatgtaataa aggattgcaa 481 ggttaaattc taaaggcagg ttaaataccg gtgctgtcgg cgacatacga aaaaacgtga 541 cagaagctcg tagatgaaac gaaaaaatca tagaacctta gttgaacttt tatttatgaa 601 tattttttat gattttataa agtcttatgt cattttactt tttattttat attatgcagt 661 atggatatta tgttcaggag ttgaatttag atgccttgtc cgacaggaaa cataacctat 721 tacagttcaa tccggcgata cgctgtacaa aatagcatca aaatataata caacctatca 781 ggcgatatta tcagcaaatc cgggaataaa tccaaattgg ctttatattg gacaacaaat 841 ctgcattccc gttgcccagg cgacattaca gatagttacc cagcctgtat tggtaaacgg 901 tgttgatata aacacaggcc tgtatcctgt acttaactat aagccggcaa atgcccaata 961 cccttatatt tatgtgccgg ttgccgagtt ttcaaaagtg ggagcaaaag tgacctggaa 1021 tgaagccaaa cagctgcttt ccgttacgac tgattattat gaaaatcaaa gaattattgc 1081 ggatctgaag gcaaagattt ctacactgga gaaaatgcct cctttcaact tcattttaac 1141 ggttacgaaa atcgtaggaa acttaagcga agaacagaaa atggagatct atggacttgc 1201 agagacaaaa actttggatg aattgcgtac aatgtcatcg gatgcgttta accaattaaa 1261 tgaaactgca gtatcaaaag atgggattat tgacgcacgc ggtggttaca cgggctttac 1321 tatggcgttt gtaaaaggag atattaagct ggtagcatcg gtaacatttt atacaaatga 1381 tcctaactta tcggaaaatt acaataaata caccgaacag cagaaagaaa tttttaacaa 1441 attttcttcg gcagcagttt atgttgcaaa taagttttta aaagaacaaa tactggcttt 1501 ataatttgca gataaattgc aagacgagag tatggcctga tgcatgcaca gagaaataag 1561 cccggcttca agacatgtaa tatatatgtg gacaatattt gatgtatatc ccccggattt 1621 atcattgtgg cattagagag gaaaaaatgc tataattata cactagaaaa ttgtggttca 1681 gttaaaataa agaagggggg atacgatgta taatcaaagc aacgccggta atgcaaatca 1741 tgttgcagat tcaaagcgtc ccgcaagaaa aaagaaaata ggttgtttag gctgctttgg 1801 atattcttta ttaacaattc tggttttggc agttggcctc tttgcattta ataccatacg 1861 aagcaagatt gaagaaagag aacagcaaaa gttggaagcc aggtttgatt atgaagaaaa 1921 attttccgcg gaagaaaaac ttacccgctc ttttgaaaaa ggtgaaattt ctgcagatac 1981 ttatgttttg cagttggcat acagcttgta tgatgttgaa aagcttgatc cgttgtataa 2041 atcagataat gatgttgatt ttccgccgga tgttgttaat gcggtattag agcatgaaga 2101 tgaacttagc gacgagacgt tggaatatat tgccagcaaa attttaatga cagatataaa 2161 aattcatccc gatgccagtc agaattccgt agcttataaa aataattggc ttcctttttc 2221 cgaatacgtg tttgctgagg atgaatatga tgttacggtt cttgataaag cgattttatc 2281 tcccggcggc aagtttttga tattttatac cgaaacggga aaatcggcgg taaaacgtga 2341 agttgttcag gaattggcag gttctgtgga aaagattgca gatgatataa gtgatttttt 2401 gggtattgaa tgggattaca attttcaagt gcttaacttt gaaagtcata tacatatgaa 2461 aaaggtttta aatgcgtgcg gcattgatga aaatgcgata aaaaaggcac ttcctgttta 2521 tatttatgag ccgccggaaa cgagtggagc attggcatgg tatatcagaa attttaatcc 2581 cgttgagaaa ttcggaaatt ggctggtaaa agtggcctct gaggagaata taattgaaga 2641 aagggctacg gtgtattctg taccttatat tgttgttaaa acttcatcca tatcgaacat 2701 ggaaaacttg aatgcaattt taggccatga actgactcat cattttcaga ggatatatta 2761 caataacctc aatcacaatc ctcctgattt tacgaacgaa acagttgcta attttgtatc 2821 tgcaagtatt aataagaata aaggaacaaa tactgtgcta aataaacatg caaatgacag 2881 tatgaacgtt cttgatagcc atttttatac aatgatagac ggaaaagctt gtgggtatct 2941 tgagtttgtt tgggcaaaat catatgtgga tatcattgaa aacggaaagc agtatctgat 3001 ggagtcgctg cttcaggaag ggaatccttt caactttctt aaagagaagg ccggagattc 3061 gtatcagctg gtatttgaag attttgcagt gcgcaatatt actaaagact atcaggaaaa 3121 aggttttatt tcaacaatat ttccgaagcc gaaagagtgg attaaccgct atatggacgg 3181 agaagagcat gagattaatt tcaattgttt acattattac tatattgata ttactatatt 3241 gatgtaaaat cttttcgcaa gtcaaagact gaaattcgta taaatagtgt cggagacgct 3301 gagtttttta taaaagtaat tggcagaaaa aaagaaaagt acagtcttgt tgatacaatt 3361 tattgcgagc cgggaaagga atttttgttc gcagattttt caaaaggtga ttacaaggaa 3421 tataatgaaa taattttagc tttcggaaat tgcgatacaa cagcgaaggc caaatatcag 3481 atgatatgtt tgtctcctgc gacgatagcc ctttatgagg cgctgaccgg gcttaaagat 3541 attgatccgt gggaaattaa cggtgactgc ataactatta atgtaaaaga ttttatgaaa 3601 ggtgcaacca cactaacgga tttatttgcc cgcataaatc cttatatttg ggctgaggtg 3661 attgatgaag attcaccgga tgttgaagaa tatgttgaac atcttcagga cgagattaac 3721 gaatttggag aggctttaaa gaaatttggg gatatgtttg attataagac cgttcgcatt 3781 tatgttatgc ctataaaaaa ttcagtgtta tccgatgatg aaattcatga taccgcgttg 3841 aaaaacatgc ctatacccag gttaaaagtt attgacaagg ctgaggacgg catgcacttg 3901 tcaatgggcg gaagtattca gcctttttct aaaactcggc ttattttcta tacggtaatt 3961 acaaaaccgg atgaaaaaat catgtatcgt attgaattgg aaaaataagt attggtgaaa 4021 atccttatat acaaaaacta aatccggctg ttttaaagga acatattaat gaggtttata 4081 tgagggcaag ccttggaaag attagctcac gggaattttg gcatgaactg ggctttgtga 4141 acggatatga acaaatagaa agagaatacc ttgatacctg tttgacttta gatggtgagt 4201 ttataagtat tgctgaagaa ttaggggctg agtatgacct tgccgttctg tcaattgacg 4261 taaaggaatg ggggaagtat ttacgggaaa aatacaattt agacaggttt ttcagggaag 4321 tggttataag cggcgaagtt aaatgcagaa aaccggacta cggtatttat gatattcttt 4381 tttcaagatt gaatgtaaat cctcaagact gtgtgtttat tgatgacagg tataaaaatt 4441 taaaaactgc gtctgaaaag gggttgaaaa cgattagatt ttgcagggag ccgcaggaaa 4501 agacttttga accggatgct gagattaatt cgtttactca gttgaaagaa gcagtaagat 4561 acatatggta gtttttatgt atttatagac tgaatttttc aacgaaaaaa ggcgaaattg 4621 ttttttgact taaggtggaa agtagtgtaa aataaaatta caagtttata ttattttctt 4681 tgtttattat agaatattat agaaattaac agacttcaat ctacaattta aaaacaaaat 4741 ataaaattat aattacaata aatacatata atttatacat catctataaa tgcatgtaat 4801 ttatgcatta tctatgcttc aatctacttt attcattttc ccaatttatc caattaacta 4861 tgcaccaaac aatttattct cgtgcaaatt tttaaattta aggagtggaa aaataatgaa 4921 caatccaatt actgccgtct gggaaatcac catggggtgc aacatgcggt gcaagcattg 4981 cggctccagc tgtgagaatg ccctggaggg agagttgacc accgaggaag ctttgaaact 5041 ttgcgatgaa ttgggtgagt tgggttttaa gtggattact ttgtccggtg gtgagcctac 5101 aacaagaaag gattggcatc ttatagccaa aaggcttaat gaaaatggga taatccccaa 5161 tatgataacc aatggatggc tgatgaatga ggagattgcc gataaagcgg tggaagcggg 5221 aatcaacaca gttgccatta gtgtggacgg acttgaagaa actcatgatt ttattcggaa 5281 aaaaggctct ttccaaagga taatgcgggc tttcgatatc cttaggacca ggaatatatt 5341 ctattcagcc attaccacaa taaacaacat aaatataaag gagcttccaa ggcttagaga 5401 tattctgatt gaaaagggag taagaggctg gcagcttcag cttgggcttc ccatgggaaa 5461 tatggctaaa aacaatgagc ttgtggctca gccttaccat atagacgaag tgatagaatt 5521 ttcctataag accgtaaaag agggttataa tatagatgtt cagctggctg actgtattgg 5581 ctattttaat ttaaaagaaa tagaagtgag gaaaaacagc tacggtggag gaagggatgg 5641 ttacaactgg accggatgcg gtgccggcaa atacagtctc ggcattctgc ataacggtga 5701 tattttaggc tgtacatccg taagagacag aagctttatt gaaggaaata tcagacagac 5761 ccctattaaa gaaatatgga tgaatcctga cagctttagc tggaacagaa aaatgaccaa 5821 ggacaagtta tccggcttgt gtaaaaaatg ctatttcgga gaacgttgtc tcggaggctg 5881 ctccaataca aggctgacaa tggaaggaag cgtctattct gagaacagat actgttcgta 5941 taatgtggca ataagcactg caagagagca gcttgacaga attgaagacg tagatgtaat 6001 gctttcaaaa gcaaagaaat ttgcagacaa tggcaatttt cagctggccg aaatactgct 6061 ttccagagcc attgaaaaag gctgtcgcga tattggggtg tttgagtttt acggatatat 6121 aagttttatg ctgggaaact accttgatgc aaagaaagca aatgaagagg ctttgaaaat 6181 aaatccggac agcgcttatg caaacaaggg aatgggtctg tctttaggaa gactgggaga 6241 attggaaaaa ggaatagagt atttgagaaa ggcaattgct ctgtccgatg aaaacttcac 6301 agacccttac tatgacctgg ctgttttgct ttatgagaac ggaaggaaag aagaagctct 6361 ggaagttctt gaagagggaa gaaaaaaata caagagtttt atagacacaa gcaaggacct 6421 ttatgatatt cttacaaatg cttcttagga gtggagaaat gctcaggcgt ttgttcaaaa 6481 aaaagtatgt atgcgtaagg caatatgatt tgacagactg tggagcagcc tgtttgtcca 6541 gtattgccca atattacggg ttaaaaatgt cccttgcaaa gatacgtgag atgacaggca 6601 ccgataccca gggcacaaat gcctatggtt taattcatgc tgcaaagcaa ctggggtttt 6661 cagcaaaagg tgttaaggcc tcaaaagagg atttgctgaa agattttagg cttccagcca 6721 tagcaaatgt aattgttgac aacaggcttg ctcattttgt agtgatttat tcaattaaaa 6781 acaggataat tacggttgcc gaccctggca agggaattgt caggtatagt atggatgatt 6841 tttgttcaat ttggaccggt gggcttgttt tgctggagcc cggcgaagct ttccaaaaag 6901 gggattatac ccaaaatatg atggtgaaat ttgcaggttt tttgaagcct ttaaaaaaaa 6961 ccgtactgtg tatattttta gcttcgcttt tatatactgc tttaggaatt gcaggctcct 7021 tttatatcaa gtttttgttt gacgacctta taaaatttga aaagcttaac gaccttcata 7081 taatttccgc aggatttgct gttatatttt tacttcagat atttcttaat tattacagaa 7141 gcatacttgt taccaaactt ggaatgagca ttgacaagtc cataatgatg gagtattact 7201 cccatgtgtt aaagcttccc atgaattttt tcaattccag aaaagttggg gagataattt 7261 caagatttat ggatgcttca aaaatacgac aggcaatttc cggagcaacc cttaccataa 7321 tgattgatac aattatggcc gttatcggag gaattctttt atatatacaa aactcttccc 7381 tgttctttat atcttttatc atcatattgc tgtacggaat aattgtgacg gtgtttaaca 7441 aaccgattca gaatgctaac aggcaaataa tggaggataa tgcaaaatta acttcggcgc 7501 tggtggagtc ggttaaaggg attgagacga taaaatcctt tggtgccgag gaacagaccg 7561 aaaaaagcac cagagacaaa attgaaactg taatgaaaag ctcttttaaa gaagggatgc 7621 tgtacataaa tctttcttcc ctgaccggta ttgttgccgg gcttggaggt attgtaatac 7681 tctgggccgg tgcatacaat gtcataaagg gaaacatgag cgggggacag cttcttgctt 7741 ttaatgcact gttggcatat tttctcacac ctgtgaaaaa cttaattgat cttcagccgc 7801 ttatacaaac ggcggtggta gcctccaaca ggcttggaga gatacttgaa cttgccactg 7861 aaaaggaact gagagaagac agtgatgatt ttgtcatatc attaaaagga gacattgaat 7921 ttaggaatgt ggattttcgc tacggattaa gaaagcctgt gctaaaaaac attaatttaa 7981 ccataccaaa agggaaaacg gtagccatag taggtgagag tggttccggg aaaactactc 8041 tggcaaagct tttgatgaat ttttacagtc cggaaaaagg ggacattttg ataaacggac 8101 acagtataaa aaatataagt ttggagttga ttagaaagaa aatagctttt gtttcacagg 8161 atgtctttat tttcagtggt actgtaaaag aaaatctttg tcttggcaat gaaaatgttg 8221 atatggatga gattataaaa gcggctaaaa tggcaaatgc ccatgatttt atagaaaaac 8281 tgcccctaaa atatgatact tttttgaatg aaagcggagc aaatctttcc gaagggcaaa 8341 aacaaaggct ggcgatagca agggcactgc ttaaaaaacc ggatattttg atactcgacg 8401 aggcaacaag caatttggac agcatcaccg aaaaccatat caaggatgca atatacggtt 8461 tggaagatgg tgtaacggtt attataatag cccacaggct gagcacaata gtaaactgtg 8521 acaaaatata tctgctaaaa gacggtgaga tagtggagag tggctctcac accgagctta 8581 tagcgttaaa aggttgttat tttaagatgt ggaaacagac agaaaacact ttggcttcgt 8641 aaaaaagaac tatctcttct cagaaagaat gcaaatcaga gataaagcaa gcattcttcc 8701 tgaggggaat agtatataag ataacttaaa aagggggtga gaccatgtca gaagcaaaga 8761 aactgaacat cggaagagaa ttgacagatg aggaacttat ggaaatgacg ggaggatcca 8821 cttttagtat ccagtgtcag aaagactata catataaacc atcactgcct gttgttaagt 8881 atggagttgt gattgacgaa ccggaagttg ttataaagta tggcgttggt ccgatagtcg 8941 gaattaagta tggtgttgaa ccaattggac caatacaacc aatgtatgga ataaagccgg 9001 tggaaacatt gaaataaaga gtcaaaatga ttttgtttta gtttttggca tggtcaagta 9061 accatgcttt ttttatggct ggaaaggctt ggtggatggt gcttgtgaga tatgatatta 9121 gtttattgta tttaaaaaaa taatatgata tgataagatt ggaaatcagt ttacaaacaa 9181 gtattaccca gataatactt tttacatata cttgtgaaat ttaatatttt atgggggtga 9241 cggatttaaa atttttagag aaaagtattt gcctgtatat tttaacctta atttaattag 9301 tttgtttagg aggaaaaatg caatgaaaaa atttcttgtt ttattgattg cattaataat 9361 gattgcaacc ttattagtgg ttcccggtgt gcaaacatcg gcagaagggt catatgctga 9421 tttggcagaa ccggatgacg actggctgca tgtggaaggt acgaatattg ttgacaagta 9481 cggcaataaa gtttggataa caggagccaa ctggtttgga ttcaattgta gagagagaat 9541 gcttttggat tcataccata gcgatattat agcagatatt gaattggttg cggataaagg 9601 tataaatgtg gttagaatgc cgattgcgac agatttgctc tatgcatgga gccaggggat 9661 atatccgcct tcaaccgata caagctacaa caatccggct ttggctggat taaacagcta 9721 tgagttgttt aatttcatgc tggaaaattt caaaagagtc ggtatcaaag ttatacttga 9781 tgtgcacagc ccggaaactg acaaccaggg gcataactat cctctttggt acaataccac 9841 tataacggag gagatattca aaaaggcctg ggtatgggtg gctgagcgct ataaaaatga 9901 tgacacaata atcggatttg acctaaaaaa tgagccccat accaataccg gcaccatgaa 9961 aataaaagct caaagtgcca tatgggatga ctccaaccat ccgaacaact ggaaaagagt 10021 ggctgaggaa actgccttgg caatattgga agtacatcca aatgtattga tatttgttga 10081 aggtgtggag atgtatccca aagacggcat atgggatgac gaaacttttg acacaagccc 10141 gtggacagga aacaatgact attacggaaa ctggtggggc ggtaacttaa gaggcgtgaa 10201 ggattatccg attaatcttg gaaaatatca gtcgcagctt gtttattcac ctcatgatta 10261 tggcccgata gtttatgagc aggattggtt taaaggcgat tttatcactg ccaatgatga 10321 acaggcaaaa aggattctgt atgagcaatg ctggagagac aattgggcat atatcatgga 10381 agaaggaata tcaccgttgc tccttggcga atggggaggt atgaccgaag gcggccaccc 10441 gcttcttgac ctgaacttga agtatttaag atgcatgaga gattttatat tggaaaacaa 10501 atataaattg catcatactt tctggtgcat aaacattgac tcggcagata ccggcggatt 10561 gtttacccgt gatgagggaa caccgttccc ggggggaaga gatcttaagt ggaatgacaa 10621 caagtacgac aattacttgt atcctgttct ttggaaaacc gaggacggaa agtttatagg 10681 tcttgaccac aagattcctc tcggcagaaa cggtatatca ataagtcagc tttcaaacta 10741 tacaccgtcg gttactccgt ctcccagcgc aactccttct ccgacaacaa taactgcacc 10801 gccgacggat accgttacat acggagatgt gaacggagac ggaagggtaa actccagcga 10861 tgtggcattg ttgaaaagat atttgttggg tttggttgaa aatatcaata aagaagcagc 10921 ggacgtaaat gtcagtggaa ctgtaaattc aacggatttg gcaattatga aaaggtatgt 10981 tttgcgtagc ataagtgagt tgccgtataa ataagacaat aaaaaacggt ggaaaaaagg 11041 ggactttggc cgctggctaa agtccctgaa ttttaaggag agaaaagatg ccaaagatat 11101 taattgttga agatgataaa gatattgtaa ataatttaac cgaatacttg cgtgacgaag 11161 gctttgacgt ggattctgcc ggcggacaga atgaggcaat taacaaaatg gataaaaaca 11221 agtatgactt gcttcttgtg gacatatcct taaaagatgg gaatggcttt gcagtatgtt 11281 cggcagcccg ggagaataat gatatcccgg ttatcttttt gtcagcttcg gatgatgagt 11341 acaatattgt taccggtctt gagataggag ctgatgatta cattgtaaag cctttcaggc 11401 cgagggagct tttatctcgc attcgaaaag ctttaaggcg aaatggcaaa gcgggagctg 11461 taatagagca tgacaatatt cgggttgaca cggttcgggg gattgttacc aaaaacggct 11521 cggagatttt cctttccgcc cttgaatatc gcctgcttct tgtcttttta aacaataagg 11581 gagctgtttt gtccagaagc aggctgctgg aggaaatctg gaacattgcc ggtgaatatg 11641 taaacgacaa tacccttacg gtatatataa agcgtctgag ggaaaaaatt gaggatgacc 11701 cgcaaaatcc gacttttatt aagaccgttc gcggactggg atacaaagtt ggtgattaaa 11761 gtgagttttt ttagaaatcc cgaaataaaa aaaggctttt tgatttttat tgttttatcg 11821 gttgtatcaa caagcatagg gtttttatat gataaaagtg tcggattttt tgtgctgtgc 11881 ctttgttttg tgtttacttt ggttcatttt gctttaacat atctaagata tcggaaaatt 11941 gcagagttta cccgtgaggt tgacagagtc cttcatggtg ctgaatctat aaactttggc 12001 agttactcgg aaggggaact tgcaattttg gaaagcgaga tatcgaaact tacgataagg 12061 cttcgggaac aggctgaagc tttaaagaaa gataagacat ttcttgccga ctccattgcg 12121 gatatttctc atcaaatcag aaccccgctt acctcaatca acatattggt ttcacagctg 12181 ttaaaaccaa agctttccga tgaacacaga atagaaattg ccaaggaact ggaactaatg 12241 ttaatgcgaa tagactggct gattacggca cttctcaaaa tgtcgaaaat tgatgcggaa 12301 gtggtcagat ttcagcgcaa aaccgtatcg gtggcagagc ttgtaaggcg cgctatagag 12361 ccgattgcaa tacccatgga gcttaaagag cagcagattg atgtatttat ggaggggaat 12421 gaaactttta tcggagattt gtcctggtcg gttgaagcca taggaaacat tctgaaaaat 12481 tgcatggaac atactccaaa gggcggcagg atagtgataa aggcctgtga aaatgctatt 12541 ttcaccgaga ttgaaattac ggacaacgga ccgggtatag acagggagga tttgcctcac 12601 ctttttgaga gattctataa aggaaaaaat tccggcgaac atagcatggg aataggactt 12661 gccctggccc gaatgataat agtaagtcag aacggtacaa ttaaagccca aaacaaccat 12721 gacggcggtg caaaatttac ggtgaggttt tacaagggag ttgtctgata catttacttc 12781 ttaagtgacg tttttgttat ttttaagtca ccttcctgtc atattggcga attataatta 12841 aagcatagac tgaacttttg ggagatgaaa gtatttatgg agatattgag ggttgaaaac 12901 gtgacaaaaa cgtacggcac cggagagaac atggtcaggg cattggacgg tgtttcattt 12961 tcggtaaaaa agggtgaatt cattgcaatt gtagggccat cgggttcggg caaatccaca 13021 cttttgcata ttttaggcgg agtggacaaa cctacaagcg gcaaggtttt tatggacggc 13081 aaggatgttt atgctcaaaa tgacgagcag cttgcaattt ttcgccgccg gcaggtgggg 13141 ctcatatatc agttttacaa ccttataccc gtgttaaatg tagtggagaa tattacactt 13201 ccggtactta tggacggaag aaaagtgaac aaagaacgac tggaagagtt gattgagact 13261 ttgaatctta aaggaaggga aaatcatttg cccaatcagc tgtcgggagg ccagcagcaa 13321 agggtgtcca ttggcagggc attgataaat gctccttcgg tggtgcttgc ggacgaaccc 13381 acgggaaacc tggattcgaa aaacagccag gaaattgtgg aacttttgaa actctccaat 13441 aaaaaataca atcaaacctt gattgttatt acccatgacg aaaatattgc gttgcaggca 13501 aaccgagtaa ttgccattga ggacgggagg atcattcgtg acgaggtgat tcggcaatga 13561 acgtttttta caaattaaca ctaaaaattc ttgaaaagaa caaggcaaga accctcgtca 13621 ccatcgttgg aattatttta tccgcatcaa tgattacggc ggtcacatgc tttatttcaa 13681 gtcttcagga ctttttggtg gatatggttg ttgcacggga gggagactgg tacggcgtag 13741 tatatgacgt gaaaaaagaa cagattgaaa gtttaaagaa agataaagag gtaaaatccg 13801 tggtatggct tcggaaaatt ggctatgcat ggctcgaagg ctctcagaac gagtacaagc 13861 cgtatttgtt tataggagcg atgggagaag gatttaagga ttcaatgccg attcatttga 13921 cagaaggaag aatgccggaa agcaactctg aaattatcct gccgaaacat gtggagacca 13981 acggcggagt gaaatttaaa attggagata tactgtccct tgaaatcggc gacaggattt 14041 ccgacggctt taagcttaac cagaacaatt cctatttgca tgagaaagac ggtggtgaaa 14101 cagaggaatt ggtagttagg gaacgacgta ctttcactgt tgtgggattt tatgaacgcc 14161 cgggatttga gccttttatt gcgccgggat ataccgcatt gacagttgaa gacaacaatg 14221 cttttagcag ttatgattat gatgtttata ttaaaacaaa gaagatgagt ggtattattg 14281 attttatgga cgaaaaattt caaggacatg gtagaagaat caacgatgac cttttgagat 14341 tcagcggagt tatatatgat ccaactttca agggaatatt gtatggactt gccggaatat 14401 taattgccct tataatgttc ggttccatcc tgcttatata caatgctttt tcaatatccg 14461 tcaatgaacg gaccaaacaa tttggaattt tggcgtctat cggtgcaacc cggcggcaaa 14521 tgctaaaaag tgtgttgttt gaggcttgtt tcttaagcct tatagggatt ccctttggca 14581 tattggcagg agttttggga ataggggtaa cgctgaaatt gaccgaagat ctgtttgtgt 14641 cttttttaca ggtggataac ggtgtggttc tggaccttca tgtatccctg ggagctgttg 14701 tggttgccat agtggttggt tttgctaccg tgctgatttc ggcgtatatt cccgcaaaac 14761 gcgccttaag aatatcgccc attgatgcca tccggcagac tcaggatatt aaaattgaag 14821 ccaaaaaggt gaaaacatca aagcttgtct ataaactctt tggatttgaa ggtatgattg 14881 caagcaagaa tttcaaacgc aacagaagaa aatatcgtac cacggtggtt tcgcttttca 14941 tgagtgtggt gctgtttata tcatcaagca gtttctgtgc ttatattacg aaaagtgcaa 15001 attcggttgt acgacgcctg gattatgaca tatcatatac ttttacatcg gatcttaaag 15061 aaaaatactc ttttgacgaa ttgtacgggg aactgtctca aataaacggt gttgccgaca 15121 gcagttacgg atatttttat agagattttg aatatgcaaa aataccgacc ggattgttga 15181 ataaagaata tataagtcat ttggaaaaga ggtatggaga aaactatatg gaaactgact 15241 tagaatatta tcttgttaac atccgagtat actttgtgga tgatgtcacg tatgaaaaat 15301 atcttaaaga gaattcttta gccagtaata caaatagaaa ttccaacgta ccgcatgccg 15361 ttgtggttga ttctatgaaa ttttatgatg cgcagcagaa aaaacattat actttaaacc 15421 ttcttgacga aggaattcac gatattaccg tggaaatgct gaaagaaaga gaggatgcgg 15481 ccggagaaaa gattgatatt gtcggtgtga ctgacagtgt acctttgggt gtgcaggata 15541 atttaccata tatgttgacc gttatatatc ctttcagtgc aatttccgca ctgcaggagg 15601 gtaaaaacgg tgaagttgat gtaacgatgt attttaagac cgaagatcac aggattgttt 15661 ttgacaggat atacaaggtt ttaaatgaaa aaggacttcc tgtgtcaaga ttaatcaatt 15721 atgcagaaac agatgaggca aaccgtgctc taattaccat tgtcaatgtc ttttcctatg 15781 gttttatcgt tttaatatcc ctgatagccc tggccaatgt gtttaacacc atttcaacaa 15841 atatttcgct tcgccgccgt gagtttgcaa tgttaaagtc cataggaatg acggagaaag 15901 ggtttagcaa aatgatgaat tatgaatgcc tgctgtacgg aataaaagga cttatgtacg 15961 gtattccggt gtccattggt gtaacttatc ttatttatcg aagtattgcg gaaggattgg 16021 aaacgaagtt ttttgtcccg tggtacagta tggctattac tgttggaagc gtgtttatag 16081 tagtgttttc aacaatgctg tattccatga gcaagataaa aaaggacaac cccattgacg 16141 cactcagaaa tgagaattta taagactcaa aagtatatgg gtgtttgtgt taaatactta 16201 aaaagccggt ctgaaatggg ccggcttttt tatgttttga agtgatgggt atagcatatg 16261 ttatgggtat tgtgatataa tccttatgaa ttttattgac aagatggtaa tttcatttac 16321 aaactgatat ttttattatt aactcgaggt gggaggttgt tatggtaaag agggtacctt 16381 tggaagagct taaggcacgt atggagcggt tccgtacaat gatgaatcaa tataatcccg 16441 aatggaaaat ggcagtgata ttcagtaaaa ttaacatata ctattttacc ggaaccatgc 16501 ctgagggcat gcttttgatt cctcgggaag atgaggcggt actgtgggtt cgcaggagtt 16561 ttgaaagggc aaaggatgaa tcgctgtttc ctgaaatcag acctatgaat agttacaggg 16621 atgcggtggg aagctaccaa aatttgccgg atacggttta tcttgagacg gagtttgtcc 16681 ccatagcgat gtttcagagg tttcaaaagt attttccttt taaaaatgtg aagcctttgg 16741 atatggtgat tgcaaaacta cggtcagtta aaagcagtta tgagctggag atagtgaaac 16801 aagccgggga aattcacaaa agagtactgg aggaacgggt gccggaaatt cttgaagaag 16861 gcatgactga ggcggaactt gcaaccaggc tgttttccgt aatggtggag gagggacacc 16921 agggaatatc ccgtttttcg atgtttgata ccgaaatggt tatagggcat atctgctttg 16981 gtgaaagttc catttatccc acatatttca acgggccggg aggatgctat ggcttaagcc 17041 ctgccgtgcc gcttttgggc agccgtgaac gcaggctcaa aaagggtgat ttggtgttta 17101 ttgatgtagc ctgtggagtt gacggatacc ataccgataa aaccatgaca tacatgtttg 17161 gctctccgct tcccgatgag gccattgaga atcacaaaaa atgtgttgac attcaaaata 17221 aaattgcctc aatgctaaaa cccggagcaa tacctgccaa tatttacagg gatataatgg 17281 acagccttga tgaaaagttt catcaaaact ttatgggatt tggaaagcgg aaggtaaagt 17341 ttttaggcca tggaattgga ctgcaggtgg atgaaatgcc tgttattgcc gaaggtttta 17401 atgaacctct gaaggaagga atggtgctgg ctttagagcc gaaaaagggg attgaaaacg 17461 taggaatggt tggaattgag aatactttta tagtgaccgg acagggagga aagtgtataa 17521 cgggagacaa ccccggattg atacctttgt attagtcgga cgaaaacaat gaacaagagg 17581 gagaattatg gaaaaagtcc agagcatatc caacggaaca aacagtattt catatactct 17641 tacccgaagc cgaaggaaaa ctgttggcat aaggataacg gaaaacggtg aggtgaaagt 17701 tgcggctcct ttgaatatcc cggacaggca gctgaaagat ataatactca agaagctacc 17761 ttggatttta agaaagcagg aggagcttag gaaaatatgt gaagaatctc ggcttgaaaa 17821 taagttcgcg gacggggaga cttttttgta tcttggaaag gaatatactt taagaattgc 17881 aaaaggagta ctgcccgaag gggttaattt ggaagaaaac tatatcgttg ttgcagcgga 17941 cgagacaaaa gtctctgtga acggacctca atatatacga aatgttttaa agaattttta 18001 tgttaatcag tttgttgata ttgcaaaaac aaggatggat tttttctctc ctaaaatagg 18061 tgtttgcccg cggaaattga ctgtcagaga acaaaagacc cgctggggaa gctgcagcag 18121 caagggtaat atcagcctta actggaagct ggtcatggct ccgatggaag ttatcgatta 18181 tgttattgtg cacgagcttt gccatatgaa agaaatgaat cattcgaaaa attattggaa 18241 cattgtaaaa tccataattc ccgactttga gctgagacga aagtggctta aggacaacgg 18301 ccaccgtttg ctaatgtagc cgtacaatat tggcacaaat gctgccggaa cgtatgcacc 18361 ggtgtttcgt gcagaagtaa atgagatata atttggatgg gataatttaa acaaattgcg 18421 ctgtatttgc atgtatgctt tgaaattctt gcgtccggat gataaaatag atatatagga 18481 acaagaaata tataatattc aattaatgtt caaatttgat gtaaatcaat agaaattaat 18541 cgaagtaata ccattcagca atccgttttt cctgtcatca ctgtaaaaac aaagtatccg 18601 ttaaatgttg aaaaatttcc ttgtaagaaa tgcatagtgt tgaaaaaaca gagtttgtga 18661 aaggggagat gcagaaaacc gatattacga aaaaaataaa tggttaaata atttattaat 18721 aatttttaaa gtttttaata aaagggggag atttaagttg aagaaaattt tggcgttttt 18781 gctgacagtt gcgctggtgg cagtagtggc cattccacaa gccgtggtaa gttttgctgc 18841 ggatttcaac tatggtgagg cacttcagaa agcaataatg ttttatgagt tccagcgctc 18901 gggaaaactg cccgaaaaca aaagaaacaa ctggcgtgga gattccgctc ttaatgacgg 18961 cgcagacaac ggtttggacc ttacaggcgg ttggtatgat gccggtgacc atgtaaagtt 19021 caaccttccg atggcctatg ccgttaccat gctcgcatgg agtgtttatg aatcccggga 19081 tgcgtatgta caaagcggac agcttcctta catactggac aatattaaat gggctaccga 19141 ctactttata aaatgccatc caagtccaaa tgtatattat tatcaggtgg gagacggagc 19201 attggaccat tcatggtggg gacctgctga agtaatgcag atgccaagac cgtccttcaa 19261 agtggatttg accaatccgg gttcgactgt ggttgctgag acggcagcgg ctatggctgc 19321 atcctcaatt gttttcaagc ctacagaccc ggaatatgct gccacacttt taaggcatgc 19381 gaaagaactc tttacttttg ccgacaccac aagaagtgac gcaggatata gagcggcaga 19441 gggatactat tcatcccaca gcggttttta tgatgaactt acctgggcga gtatatggct 19501 gtatcttgca acaggagacc agtcttatct tgataaagca gaatcctatg aacctcattg 19561 ggaaagggaa agaggtacaa ctttaattag ttattcctgg gctcattgct gggataacaa 19621 attgtacggt tctttgcttt tgttagcaaa aattaccggc aagtcttatt acaagcaatg 19681 tattgaaaac catcttgact attggaccgt cggatttaac ggaagcagag ttcaatatac 19741 tccaaaagga ctcgcatatc ttgacagatg gggttcattg agatatgcaa ccacacaggc 19801 gttccttgcc agcgtttatg cggactggtc cggctgtgac ccggctaagg cggctgtcta 19861 caaggaattt gcaaaaaaac aggtggatta tgcattagga agcacaggaa gaagctttgt 19921 agtaggtttt ggaaaaaatc cgccaagaaa tcctcaccac aggacggccc acagctcatg 19981 gagcgcttta atgaccgaac ctgcggagtg cagacatatt ctggtgggtg cattggttgg 20041 cggaccggac ggttcggatt catatgttga caggctcgat gattatcagt gcaatgaggt 20101 ggccaacgac tataatgctg gatttgtagg tgctcttgcc aagatgtatg agaagtatgg 20161 cggagaaccg attccgaatt tcgttgcttt tgaaacaccg ggggaagaat tttatgttga 20221 agctgcggta aatgctgcag gacccggttt tgtaaatatc aaagcttcaa taatcaacaa 20281 gtccggttgg ccggcaagag gttcagataa attgtcagcc aagtattttg tcgatatttc 20341 cgaagctgtt gcaaaaggca ttactttgga tcaaattacc gttcagtcga ctactaacgg 20401 cggagccaag gtttcacagc ttcttccgtg ggatccggac aatcatattt attatgtaaa 20461 cattgacttt acgggaataa acatattccc cggaggaata aatgaataca agagggatgt 20521 atatttcact attacggcgc cgtatggaga gggtaactgg gacaatacca acgacttctc 20581 cttccaggga cttgagcagg gctttacaag caaaaagact gaatatatac cgttgtatga 20641 cggtaatgtg agagtatggg gtaaagtacc ggacggaggt tcggagcccg atccgacgcc 20701 gacaatcacc gttggcccca ctccttcggt tacaccgaca tcagtacctg gaataatgct 20761 cggagatgtg aattttgacg gaagaataaa ctcgacggat tattcacgct taaaaagata 20821 tgtaataaag tctttggaat tcacagatcc tgaagagcac cagaagttca ttgcagctgc 20881 ggatgttgac gggaacggaa gaataaactc cacagatttg tatgtgctca acaggtacat 20941 attaaaactt attgaaaaat tcccggctga acagtaacgg cattaatatt caataacaat 21001 tatcaggctg ctgcgaaagt tgctttttgc ggcagctttt atttttattg caaaactacc 21061 tgtattattg ataaaataga ataataagag aggcaatgta tggaatttga gcattgcctt 21121 ataaaaagtg tgtcaaactg tatgtaaaaa gataaacaat gcgggggaat tatgctgaaa 21181 agaagctttg caatcggagc attgactgat ataggaaacg tgaagaaaac caatgaggat 21241 aacattcttg ttaaagtagg agatgaaaaa aatggtgaat tcggtctttt tttagtggcc 21301 gacggaatgg gaggacttgc cgcgggagag gtggcaagcg ggattattgt aaatgagttc 21361 aatttgtggt gggaacggca acttcccggg attttaaacc aggaaggaaa tacggtcttg 21421 gacacagata cggttttaaa tgctataagc tgggagctgg acaggcttat acaggacata 21481 aacaaaaaaa ttatccgctt tggattatca attaatgcca aggttggttc gactctgaca 21541 ttgcttttta tttatcagaa caaatatctt ataaaacacg taggggacag cagaatatac 21601 agaattaaca gttccatcac aaaacttacg gaagatcatt cgtgggttgc ccagcaagta 21661 aaggaaggga agataaaaga ggaggaagca aagtatcatc cgaaaagaaa catacttacc 21721 agatgccttg gagttatgga gaatttggag atatttgaag cttgcggtga tatttcggac 21781 gatgacggat ttttggtttg cagcgacgga tttcacaact atcttgatga gcatgaaata 21841 tattgttccc tttcttcctg taaaaaagaa gatgctgacg ttcaaaaaac tttaagggag 21901 cttcttgaga tagtgaaatt aagaggagct gccgacaata tttcagctgt tgcggtatgc 21961 cagcatatat acagagatta cagcgacagt atattgaata ttaaaggaat aattaacagg 22021 ataacgggta attttggcgg gtggtgaggt acaatactga taagatgggt tgaaatagcg 22081 gttcttgttc tgattgctct tgtaagcgac attcggcact acaagataag aaacaaactt 22141 actttttcat ttatgtttat aggaattgtg accaatctcg tattggatgg agtacgggga 22201 cttttagatt ctttgcttgg tattattgtt ccctttttat tgttgattgt attatacgct 22261 ttaaggatgc tgggagccgg agatgttaag ctttttagcg caataggagc cgttttgggg 22321 gttagagccg cgctttggat aatggcctat tcttttttgg cgggaggtgt aattgcatta 22381 attatcctta ttatcaatcg aaacggaaaa gaaagattga tgcatttatt taattattta 22441 aagactgttt ttctcacatt cagcatacag ccttacacca attttgaaga taaggacgga 22501 aaagccgtat tcagaatgac atatgcgata acatgcgggg ttatggtgtt ttttgttgaa 22561 gtaatgctta agatgaagta gaataataat aaatatatta tttggtttaa ggatgaatat 22621 gccatgggaa aaacaacgga tgatatattg gctaaaattg gatgtaaaaa cacaaaatca 22681 aggaaagcag ttattgaggt tcttgaaaat gctgagaatc ctctttctgc agaggatata 22741 tttttatgca taaaaaaaca gggttcgtcc gtcaatctgt ccactgttta cagaaccctt 22801 gaccttatgg aaagcaaatc cgttgtaaac aagattgtga tgatggacgg taaagcaagg 22861 tatgagctta cggtggacgg tcacaggcat catttggtct gtacaaattg ccataaatca 22921 gtgccgatag atttttgccc tttggaaaat atggaaaagg atatcggtat gagaagtgat 22981 tttgacataa ccggtcataa aattgaaatc tatggtatct gccctaattg taaaaaagaa 23041 taaggataaa tagtattgct tgactgtatt gcgtcgtcca atatataatc aaattaaatg 23101 caaatgattt gcatttgaaa taagttgctt gaaatatagt taatatgaaa atgatttatg 23161 gatataatta actgtaaatg gattggctat aatagttaat ttcgggagga cgctttttat 23221 gagaaagaat acaaaaaagg tggcttttct ggttgcatgt ctggtatttc tcattacggg 23281 ctgttttggc aactcaaagg tgggagagcg aaaggacagt gataaaatca atgtatatgc 23341 cagtttttat accatgtatg attttgcaaa taaaataggc ggcgacagga ttaaccttgt 23401 caatattatg cctgcgggaa cggaacctca tcactgggaa ccgtcaccga aagatattct 23461 tgagattgag aaagctgacg tgtttatata taacggagcg ggtatggagc cttgggtgga 23521 aaaggttctg ggttctataa ctaacaaaga acttgtggtg gttgaaacat caaaaaatat 23581 agaacttctt cgtggcggcc actatcatga tgaagaaaat gcggaggaag aatccgacgg 23641 tcatgatgac cttgcatacg accctcatgt gtggttaagt cccaaaaatg ccaaaaagca 23701 aatggaagca ataaaagatg cttttgtaaa agcggatcct gaaaacaaag aatattatga 23761 aaaaaatttt gaagacaatg tcaaaaagct tgacgatctt gacagagaat acagagaaga 23821 actggcgaag tatacaaaaa aggatattgt tgtgggacat caggcttacg gatatttatg 23881 caaggaatac ggactaagac agtatgccat tgaaggcctt aatgcggaat ctgagccgac 23941 gccggccaga atggctgaaa tagtaaagtt tattaaagaa aatgatataa aggtcatatt 24001 ttcggaaaaa ctgctaagcc agaaagtacc gaatgctatt gccgctgaga caggagttag 24061 ggtggaattt ttaaatcccc ttggcggact tacacaggaa gagattgatt cggggaaaga 24121 atattttaca gtaatgaggg aaaatctgga ggcgttaaaa aaggcttttg aataaaaacc 24181 ggattagagg ttgattttgt atgggaaaag ttatagaggt aaatgattta agtttcggtt 24241 acggggagag gctcatattt aaaaacgtgg gcttttccgt tgaaaaaggg gattttgtcg 24301 gaattatagg tcccaacggt tcagggaaaa gcactcttat aaaactgctt ttgcggcagc 24361 ttaagccgat taaaggccaa atcaagcttt taggccagga tatcgaaaag tttgaccagt 24421 ggaacaagat aggatatgtt gcccaaaaag caaattcctt taacaccagt ttccccgcaa 24481 cggtggaaga agtggtaagc gccaatttat tccccaaaat cggacttttc aaaaggataa 24541 aaaacaagca cagggagctt gtttacaaag cgctcgaaac tgtcgggatg gaggagtata 24601 aagaccggct gatcggaaat ttgtcgggcg gacagcagca gagagtgttt atagcaaggg 24661 ctctcgtgtc ggagccggaa ttgatttttt tggatgagcc caccgtaggg atagattccg 24721 agtcggaagg agctttgtac tgtcttttgg ggaggctcaa ccaggaaaag aaaataacaa 24781 tagtcatggt tactcatgat atcggagctg ttattgtgca tacaaacaaa attgcgtacg 24841 tgggagacaa aggcctggta atgaacgaaa acaccaaaga ttttgtgaaa aacaatcttg 24901 gaggagtata cgggtatgat gtgaattttc atgccaacag gcattgctgc acgaactgct 24961 ggaagaaagg agctgtataa atgtttggca ttttcggtga ggacttcatt ttgaatctgg 25021 gatttatgca aagggcatat tttattggta tgcttatagc cataatggca cctgccatcg 25081 gagtgataat agtcttaaga agacagtcca tgataggaga ttccctttcc catacttctc 25141 ttgcaggcgt ggctttcggc ttgattgccg gcatcaatcc catagtcgga gcaactttgt 25201 tttcaataac tgcggcattg ggaatagaga aaatcagaag agctttccca aaatatgccg 25261 aagtgtcgat agctgttatt atgtccacgg gaattggact tgcaggagta ttgtccggtt 25321 atgtaaaaag cggattttcc ttgtcttcct atttgtttgg aagcattatt gcaatatctg 25381 attttgagct ttgcgttata gttgttttga gcgccgtggt aatagtgact tttgcagcat 25441 tgtttaaaga actgtttttc ataacctttg atgaagaggc cgcaagactt gccggagtgc 25501 ctgtcaaaat gattaacttt gtttttgccg ttcttacggc agtgacaatt gcggtgtctt 25561 ccaggatagt gggcactttg gttatatcct cgcttttagt tcttcctcct gcttcagcga 25621 tgcagatagc aaaaagcttt aaacagacaa ttgtttattc tttgttgtac ggaatttttt 25681 ccatagtaac gggccttact ctttctttct atctggacat ggttcccggc ggtacaatag 25741 tgctgataag cgtgatttgt cttgtattaa cccttgttta taagaatctg gttaaaggat 25801 tgattgcaaa aaaggtatta accgggacaa attaagtatc tttcgtgtat ttttatatat 25861 cgtttttata tttaaatttt ttgttagcac tcaccttaaa tgagtgctaa aattgtcttg 25921 acaaattttt agctgtaaag gtaatatatt tattagtaca aattagtcgg acaatctatt 25981 atcaggatca ggagggaccg taatgaatcg tgaaagtggt tgcatatcta tccatacgga 26041 gaacatattt cctattataa agaaatggct gtattcggaa aaagatattt ttattcgtga 26101 attggtttcc aacggcagtg acgcaataag taagctgaag aagctggtat ccattggaga 26161 ggcggaagtt gacggcaatg aaaaatatta tataaaggtt gttgtagaca aggaaaaaaa 26221 gactcttcag ataattgaca acggtatcgg aatgaccggg gaagaggtaa aaaaatatat 26281 aaatcagatt gcgttttcag gaataaagga ttttgttgaa aagtacaagg ataaaggcga 26341 agaagcccag attatcggac atttcggtct gggattttat tccgctttta tggtttcaag 26401 caaagtccag attgacaccc tgtcctatca gaaaggtgca caggctgtaa ggtggataag 26461 cacaagcggt attgaatatg aaatggagga ctctgacaga acggaaaggg gaactaccgt 26521 aactctttat attgcggaag acagtgaaga attccttgat ttttacaagg taagggaaac 26581 ccttgtaaaa tatttctcat tccttcctta tgaaatatat ttggaggatg caaatgcagc 26641 aaaggaagac aaaaaggaag gcggagataa tgaggagaaa aaggcggaag aaccaaagcc 26701 tataaacgat acaaatccgc tttggctgaa gaacccaaag gattgtaccg agcaggaata 26761 caaggacttt tacaaaaaag tattctttga ctttaatgat cccttgttct ggattcacct 26821 taatatggat tatcctttta acctgaaagg aattctttat ttcccgaagc tcagaaacga 26881 gattgataat tttgacggaa aaatcaagct tttctgcaat caggttttcg ttgcggagaa 26941 tattaaggaa gtcattccgg agtttttgat gctccttaaa ggtacgattg actgtccaga 27001 tcttcctctt aatgtatcaa gaagcttttt gcaaaatgac ggctacgtaa acaaaatttc 27061 taaccacatt acaaagaagg ttgcggacaa acttatttca atatttgaga atgagagaga 27121 aagctacaac aaatactggg atgatataaa tccgtttgtt aaattcggat gcataaagga 27181 aaagaagttt tatgaaaggg taaaggatat aattatcttt aagacgacgg gcggagaata 27241 tgtgacactg aaggattatc ttgaacgcaa taaagacaag catgagaaca aggtattcta 27301 tgtaactgat gaaaaacagc aggcacagta tataaagatg tttaaggata ataatatgga 27361 agctgttatg atgaatacgg taatagacac tcacttcata cagtttatgg aaatgaataa 27421 cagcggtgtc aagttcctgc gcatagatgc cgacttgagt gaaagtatga aagataaaga 27481 aaacaatgtg gatgaaaatt cacaaaagga gatttcagaa gcccttgaaa agatgtttaa 27541 agaaagtctc aataatgaca agctcagaat aaaagttgag gctttgaaat cttcggcatt 27601 gccgggaatg attctgatta gtgaacaggc aagaaggata caggagatga gcaggtggta 27661 cggaggattt aatttggaag gactttacgc agaggaagaa acccttgttt taaacagcaa 27721 cagcggtttg atcaaatccc ttctgaatct taaggacaaa gaggacagaa aagaggatgt 27781 caaacttata tgcgaacata tttatgacct tgcaaaaatg agccataagc agctcgaacc 27841 ggatgacatg acaaagttta ttgaaaggag caattcattg cttacaaagc ttgcttccgg 27901 tctgtaagag attggcggta agagaagcga taagagaaat tgacaggaag agattccctc 27961 caattgctaa gattgctaat aggatttcag taagatttta taaaaatgtc cttcggaaaa 28021 taaaagactt tcgtaaggac atttttataa acatttattt tgcaagttgt tattttgaag 28081 ttgttatttt tttgcctggt ccttgtttct gatttccact cttctgattt ttccgcttat 28141 ggtttttgga agctcatcaa caaactcgat aattctgggg tacttgtaag gtgcggttac 28201 tttcttgaca tgctcctgaa gttcctttac aagttcatcg caaggagaat aatttttggc 28261 aagaacgaca gtggctttaa ccacctgacc tctgatagga tccgggacag ctgttattgc 28321 gcattccaaa accgcgggat gctccaaaag ggcgctttct acttcaaaag gcccgattct 28381 gtatccggag ctctttataa cgtcatcagc cctgccgaca aaccagaaat aaccatcctc 28441 atcgcgccaa gccatgtctc cggtataata gatatcatcg tgccatacct tttttgtaag 28501 ctcagtatcc ctgtaatatc cgtcaaacat tcctataggt ttgcttttat ccgttcttat 28561 aactatctgg ccttcctcac cgacttcgca aggattgcca ttttcgtcaa gaatatctat 28621 gacatagcct gcagacggct tgcccattga acctggcttg ggttccatcc aggggaatgt 28681 acctatggtc aaagtaagct ctgtctgacc atatccttcc ataagcttga tgcccgttgc 28741 tttgtaaaac tggttgtata cttcaggatt cagtggttca cctgcaacgg tacaatattt 28801 cagcttgctg aaatcatatt tggttaagtc ctcttttata aagaacctgt aaattgtagg 28861 aggtgcacag aaagtagtaa caccatactt gcatattaca tcgagaagat cctttggaac 28921 aaatttgtta tcatagtcgt atacaaaaac agcacttccg gcaatccatt gaccgtagat 28981 tttaccccag gcggcttttg cccatccagt gtccgcaacg gtaaggtgca gtccgccgtc 29041 aattacattc tgccagtatt tggcggttac aatatggccc aaaggataag taaagtcatg 29101 ggccaccatt tttggcattc cggtggttcc tgaagtaaag tacaaaagca tgatatcgtc 29161 attagttgtt gcatctttgc ctgttggtct ttcaaaatgt gaagattcgt tttcgatttc 29221 tttgttaaag ttgtaccagc cttccttgtc tctgccgata agagcttttg ccataacagt 29281 gggtgattgc tccagtgatt cttcaacgtg ttttattact tcgtcttcgc caacacatac 29341 aatcattttg atgtcagccg cattgtttct gtaaattatg tcttttgcgg taagaagatg 29401 agtggccggt atgcatgccg cgcctatctt gtgaagagcg agaattgcaa accagaattc 29461 gtaacgcctt tttaaaataa gcattacacg gtcgcctttt tttattccca ctctcttaaa 29521 gaaatttgcg gctttgttgc tgtactcttt taattggccg aaagtaaatg ttgcttcctc 29581 gcccctatca ttacaccaga ctaatgccac tttttcagga gttttgtctg caatttcgtc 29641 ggcaacatca taagcaaaat tgaaattttc aggaatgttc aatttaaaat tttgaacaaa 29701 atcgtcatat gaattaaaat ttacttttga caaatatttc tctaacatta tataaaacct 29761 ccattataaa attatagcca gaaatttcgc aggcttgcca ttcatagcct tcatgccgtg 29821 ttttgcgccc gagtcgaaga acagggagtc accttcatta agtatgattt catgaccatt 29881 gataattacc tttaaaacac cttcgataac gtagttgaat tcctgacccg ggtgggaatt 29941 gtagttcact tcggaatttg agtcgggttc aacggtgaca aggaatggtt ctattttttt 30001 gtttgcgaaa ttgtatgcaa ggctttgata cttatagtcc tttcttcttt ccacgcttac 30061 acccttgtct tttctgacaa cacaatatgt atggagcttt ggagcttcgc ctgtaaggat 30121 ttcggaaagc tcaacgttaa atctgccggc aattttgaac aacaggctga ccggtatgtc 30181 tacgttgccg ctttcgtatt ctgtataggt tttgctgtca atgcccagtt cccttgccag 30241 cgtttccgcg gaaataccgg agatttccct aagttcctta attcttttac tgatttgttt 30301 gatttgctca gacatggaac catcctttct gtattttaat aaactcggtt ttaataaact 30361 tgtccacgac gataatactt cttttatcgt aacataggag aagccggtat gtaaagggaa 30421 agaggacaga gtggttaaat ttttggttgt ggttgtatgt tgattgttta cattggattt 30481 gaatgtgtgc gaaggagctt gatgaattcg gaagaagctc tggagagcgg tacatttttc 30541 atggtgatga ttccaagttt tctaagggta atgtcttctt taagctttac ttcaaataga 30601 gtcccttttt ttagttcgtc ggcgacgctt tctttcagaa ccagagcaat acctagtcca 30661 atttttgcaa actctacaag aaggtcaatg ctttccaatt ctatctccgg tacaatgcca 30721 attcctttgg aggaaagata agagtcaata ttccgccttg tcgaagtgcc acggtcaagc 30781 atgagaagag ggtaggaggc aagggttttt atgtcggttt cctggttttt aagcatgctg 30841 aacttgtcgg aggccacgaa tatatctttt acggttaaaa attcttcatg gtggatttta 30901 ttactgtcct gcaccgggag agttactatg ccaaagtcaa taagcccttt tttcagtatc 30961 tcttcaattt gcgacgaagt tctgtttatc acctgtattt taatattagg atagtttttt 31021 atgaattttt ctatataagg aattaaaaaa tatttgcaga ctgtgtcgct ggcaccgatt 31081 cttatctcac ctctttccat attttgggtc tgatatattt tatgttcggc tgtttttatg 31141 aaattgtaag cctgctcaat gtgtttaaac agtatttctc cttccgcggt aagctttatt 31201 tcccggtttt ttcgaaaaaa gagcttggaa cccagttttt cttcaagact ttttatagac 31261 tggcttaccg ccgactgtga aacatgaagc gtgtcagcgg cagctgaaaa gcttttagct 31321 tttgccgtat gataaaaaat tttgtacaat tcaaagttta tatccatata agtacctcta 31381 atacatctta ttaatattat taattttact tatttatttt atcatattat aatgtatttg 31441 tatccgtcaa aatactgaaa aaataatttg aaagaggtac aggagtatgg ttagaagagt 31501 ttttgttgaa aagaaaaaag gatttgatct ggaagcccag agaatgtaca gggatttgaa 31561 agaaaacttg agaatcgccg gactttccgg tgtaaggcta attaacaggt atgatgttga 31621 gggaatatcc gatgaagagt atgaaagcgc aaagaggact atattttccg agcctccggt 31681 ggaagaggtt tttgacgaaa caataagtat agatgaaaag gacaaaatag ttgccataga 31741 atatttgccg ggacagtatg accagagagc agattctgca tctcaatgta ttcagatact 31801 gacccatggg gaaagaccca atgtcaaagt tgcaaaactt atagtgcttc agggggatgt 31861 atcgcaggaa gagtatgaaa aagtaaaaaa atatttgata aaccctgtgg aatgtcagga 31921 agcgtctttg gaaaaaccgt caactttgga tgtggaagta accgttcccg aggatgtaaa 31981 agttttaaag ggatttgtca atatgagccg ggaagaactc aaagcttttg cggacagcat 32041 gggtttggca atgtctctgg aggatctgga attctgccaa aaatatttca gggatgatga 32101 aaagagggac ccaaccatca ccgaaataag ggttattgac acctattggt ccgatcactg 32161 ccgtcatacc acatttctta caaggataca gaatgtggat attcaagaag gaagatttac 32221 tgctcctgta aaggaggctt acgagagtta tcttcaatca agaaagtttg tctatggcga 32281 caaagagaaa gatgtctgcc ttatggacat tgcggttatg ggcatgagag aattaaagaa 32341 aagaggattg cttaacgacc ttgatgagtc tgatgaggta aatgcatgca gtatagtggt 32401 taatgtggat gtaaacggaa aaaatgaaga gtggcttgtg atgttcaaaa atgaaaccca 32461 caaccatcca acggaaatag aacctttcgg aggagctgcc acctgtcttg gaggtgccat 32521 aagagacccg ctgtcgggaa ggtcttatgt gtaccaggcc atgcgtgtaa cgggaagcgg 32581 cgatccgcgt accagcatag atgatacgct gcccggaaag cttccgcaaa gaaagataac 32641 aacggaggcg gctcagggct acagctccta tggaaaccag ataggccttg ccacaggaca 32701 ggttgctgaa atatatgatg aagactttgt ggcaaaaaga atggaaatag gtgctgtaat 32761 cggtgctgct cctagaaaaa atgtaaaaag agaaaagcca aaagcaggag atgtaatcat 32821 acttcttggg ggaaggacag gccgtgacgg ctgcggaggt gctaccggtt cttcaaagga 32881 gcatacggaa gagtctttgc ttacctgtgg agccgaagtg caaaagggta atcctataac 32941 tgaaagaaaa attcaaagac tgttccgaaa gcccgaggtc agcacgatga ttaaaaaatg 33001 caatgacttt ggtgccggag gagtgtccgt tgccataggg gagcttgcgg aaggacttag 33061 aataaatctt gacgcagtgc ctaaaaagta tgaaggtctt gacggtactg agcttgccat 33121 ctcggaatcc caggaaagaa tggcggttat ggtggcaaaa gaaaacgtgg atgctttcat 33181 taaagcttca aaagaagaga atcttgaggc cacacctgtt gcggaagtga cggatgacag 33241 aagacttgta atgtactgga gaggcaaggc cattgtagat attaagaggg atttccttga 33301 taccaacgga gttaagcaaa ataccaatgt cctggttgcc gctcctttgg aagaagagta 33361 ttattttgcc gggattccaa aagaggctga ggattattca aaggatcttc gtgatgcatg 33421 gattcgaaac ttgcagagac taaatgtatg cagccagaaa ggacttgttg agagatttga 33481 cagtaccatc ggtgccggaa cggtgctgat gcctttcggc ggaaaatacc agctcacgcc 33541 ttcggaagga atggcggcaa agattccggt accggacgga gatacaaaca ccggtacgct 33601 tatggctttt gggtacaatc cttccattgc aaaatggagt cccttccatg gagccatgtt 33661 tgccgtgata gaatctgttg ccaagattgt tgccatgggc ggaaatcaca aaaaaataag 33721 attgtccctg caggagtatt ttgagaaact tggcaaagac cccaaaaagt ggggtaagcc 33781 ctttagtgct ttgcttggtg catattatgc ccagaccaaa atagggatac ctgccattgg 33841 aggaaaggac agcatgtccg gaacctttaa ggacatgaac gtgcctccga ctttggtttc 33901 ctttgccgtt gcaacaatgg acgtaaatta tacagtgtct tccgagttta aaaaggccgg 33961 aagcaaagtg gttctcattc ctcttaaaat aaatgaaaat ggagttccgg attttgctca 34021 gctggataaa aattatgcgg ctgtgcatca aatgattatg aacagaaaag tgcttgcggc 34081 ccacactgta agaagcggcg gaatttctga agccataagc aaaatgtgct ttggaaacat 34141 gataggattc aaatttgagg catcagtgga tgcaagaagg ctttttgagc cgctttacgg 34201 gtctattgtg cttgagttgg atgaaagctt aaatttggat gagttgttga aagatgtgga 34261 atatgaattt ttgggtgtta cccaggagaa gacgacaatt gactttggta atgtcggcct 34321 tgacctggtg gagctttgcc aaaaatggca ggagcctttg gagaaggttt tcccgacggc 34381 tactgagcct gtaagcagta ctcccaaaca gtataaattt gaaaaaagaa acagtataaa 34441 gccctcggtt tcaatagcaa aaccaagaat attcatgccg atattcccgg gaaccaactg 34501 tgagtatgat actgccaggg cttttgaaaa ggccggcggg gtggtggaca tgctcgttat 34561 taaaaacctt actccgagcg aaatagatga atccataagg gaaatggcaa aaagaattga 34621 caattcgcaa attgtgatga tacccggagg gttcagcggc ggtgatgagc ccgacggttc 34681 aggaaaattt attgccacgg cgtttagaaa tccaagggta aaagatgcgg taatgaggct 34741 tcttaaagag agagacggac ttatgctggg tatatgcaac ggcttccagg ctcttataaa 34801 gcttggactt gtaccttatg gtgaaatcag ggaccttaac gaagacagcc ccacccttac 34861 ctttaacaca ataggccgtc acgtttcatg tatggttagg acaaaaataa catccactct 34921 gtcgccatgg tttaacaatg taaaggtggg agatattcat accatagccg tatcccacgg 34981 tgaaggaaga tttgtggcaa gtaaagaagt gcttgaaatg atggaaaaga acggtcagat 35041 agcaacccag tatgttgacc ttgacggtaa tgcaacctat gacataaggt ttaatccaaa 35101 tggctctttc gaagcaattg agggcataac aagcccggac ggaagagttc tgggtaaaat 35161 gggacattct gagagaatag gaaccaatgt tgccaaaaat gtgccggggg ataaggacca 35221 aaagttgttt gaggcaggag taaactattt taagtaagat ttccctttaa aagctgaaaa 35281 atttttatgt agtatttata aaatatatgt tataatcaaa aagcagggaa caagacaaga 35341 ctttttttga cttctgttag gggtgggggg atgaactgaa taaagacgaa tgagagatat 35401 ttatagattt atagaaagtt tacaattttg aaacaattag gacaagttta aatgctataa 35461 ttgttttgtc ttaagaaaga aatctggatt atcagaaaat ttggtattct ttaaaaatta 35521 aaaaaaggat gaattaagat gaaaaaatca aaaagtatta tattggttat tagtatagtt 35581 gtagtgctga ttgcgggttt gtcagtggca acttatttta tactgaaacc cttgtttgga 35641 gaaaaggatg aaagtaatat ttctccgatt accaaacagt tgacggaaga agaggcaagt 35701 aaagtaattg ctgaagtaaa cggggagcag atactataca aagatttcta ttttatatac 35761 agccagcagg cggcatatta tggtcttact actgaggatg aagattcact gagtgacgat 35821 acgaaagaaa tattaaatac tataaaaaaa gagttgttga ctcagttgat tcagcaaaaa 35881 cttgcaaaac aaaaggcaaa agaagcagga tatgaagtaa cgaaggaaag acttgatgag 35941 gcttcggaag caattgaaga gatgattcgt aatatggcgg agcaaatgaa acttagcagt 36001 ccgtccgaag ctgaaagcag agattttctc aaagaagcaa gggacttcat taatagtgag 36061 cttaaagcta tgagaataac gatggacgag tatataagag atactgccga atatatgatt 36121 gtaacggatt ttatggaaga ccttacaaag gatattgttg taaccgacga agaaatcaag 36181 aaatattatg acgaacagtt gaagatccag caggaaaatc cggaagaagc tgcgtatgcc 36241 gaagtacaat tgattcagcc ggcaagctca agggtaaaac atatattgat agctttacct 36301 gaggaagaac agcaggagta ccaaaacctg aaaagtgagg gaaaggatga ggaagcagag 36361 gcatatttga aggaaaagct cgaagcaata aagccaaagg ctgaagaagt actgaacaag 36421 gcaaaaaacg gagaagactt tgaggctctt ataaaagaat acggtgaaga tcccggaatg 36481 gaaagcgaac agtacaagga cggatacacc gttactaaaa acagcggatt tataaagagt 36541 tttgaagatg cttccctggc tcttggagta ggcgagatat cggatcttgt tgaaggtcct 36601 tacggatatc atataataaa agtgtatgag aagacggaag caaaaccgta tactcaggaa 36661 gagaaaaaat ctgagattga aagtctttta aagagtcaaa agaaaacgaa tttcatgaat 36721 gaaaaaatga aagagtggga aagtgcttct acaatagtaa ggcatgatga tttgctgtaa 36781 tgctgtatga ttaaaaatcc tggcggcgga ttaggctgcc aggattttta gttgtttgct 36841 tattatacaa ttgatatatg gttatcccgc agccaaaaat ccacctggat aagataggca 36901 agcatttggg gctgtgccat caactggccg aaccagggat ctgtgttgtc cgaatttcct 36961 tcggccatgg accttaccac ttttacgtca attaattgat gaagaggtga actgctgtcg 37021 tttaatattt cgagcagcca tttgctgaca gcttttttat atgaaggatt atgagttttc 37081 gggtatgggc ttttctttct ctcaattata tcatctggaa gtatgccttt tagagcctgt 37141 cttaaaagcc ctttttctct tttgttgtac attttcaact cccatggtat gttccatacg 37201 tattggacca gtctgtggtc gcagaacgga acccttactt caagacccga tgccatactc 37261 atgcggtctt ttctgtcaag caaggtggcc atgaaccagt tgatgtttag gtaaaagatt 37321 tctcttcttc tggcttcaat tctgttttcc ccttttaagt gcggaacctc gcttagagtt 37381 tctctataac gtctttggat gtattcttca ggctttatca aattcaaaat ctcaggggac 37441 agtatttttg tcctttcgtg taccgaaacg gaccagggga aagtatcggc aaacagcatt 37501 ttctcattat gaaaccacgg atatcctccg aatatttcat ccgcacattc accggataat 37561 gccacaaccg aaaatttttt cacctcccgg cagaaaagaa acagggatga gtcaatatct 37621 gccattcccg gcaggtcccg tgcctttaca gcgtcaataa gagcgtcaac cagctgtggt 37681 gtgtcaaatt ttacatagtg atggcatgta ttaaagcttt cactcatttt ttttatccag 37741 ggttcatcgg agtttggctg aaacatgctg ggcttaaaat aaatgtcatt gtctacataa 37801 tctacagaaa aagtgttaag ctgtcctttg ccctgggagg caaaagtctt tgaagcaaca 37861 gccgtaatgg cacttgaatc aagtccgccc gacagaaaag tacagacagg aacatctgcc 37921 acaagttgcc ttgtgatggc atccaatacc aaatctctga ctttggatat ggtggctttt 37981 tcactgtcgg tatggggata actttccagc gaccagtatt ttctgatctg tattccgttt 38041 atatcaaaaa tcattgagtg agcgggtttt agttcataaa catctttgaa tataccgtgt 38101 cccggtgttc gggcgggtcc cagcgcaaag atttccgcta agccttcggc atccaatttt 38161 ggctccacaa ggggatttgc caggagcgcc tttaattcag agccaaatat caaagaatct 38221 cctctttggg cataaaacag gggttttacg ccgaatctgt cccttcccag aaaaagcctc 38281 ttttttcctt catcccaaat tccgaaagca tatattccgt ttagatgttc gacacatttt 38341 gcaccccatt caatatagga aacaagtaaa acttccgtgt cagagcttgt taaaaattca 38401 tggcccctgg attcaagttc gtttcgcagg tccgcagtgt tgtaaagttc cccgttgtat 38461 gtaataacgt acgtgttttc accctgcctg cgaaccatgg gttgaattcc gccttccggg 38521 tcgacaacta tcaaacgctt atgggcaata agcgcatttg gagaaatcca acttcccgat 38581 gcatcgggtc ccctgggggt cagcctgtca atcattgaat ttaatatttc tttttgattg 38641 gtcaagtctg atttaagatt tatccatcct gcaataccgc acatattgat atcaactccc 38701 gatattagat aaaaataaaa aggtgccctt taatgacttg cggcaccttt gcctgaagtt 38761 taagtctttt atatcaataa tatatgcata aaaggcatgt tttgttgctt caagcctgta 38821 tgaaaattta tatgaaaatt aatcattttt tattactttt aaatattttc cgaatgaatt 38881 ttttccgata cttgttacag cgatttaaat aacagagttt atatgcatat atttttgacg 38941 gttaaaatat gtataatgca ggattaataa gaaaattgga agtataaaaa atgaagtttt 39001 atgttgtgaa agtaaataat ctcataaaat atgctttttt agcagttatt gtattggctg 39061 tctcattctt tgtttatttt tcccgggaag acgttgtagg tgcatttcaa caaaaaagag 39121 aaattcccat ttattctgtg gattatcccg aaaagaaagt tgcccttacc tttgactgcg 39181 cctgggggag tgaggatata ccggacattc tgaataccct gagggagcat gatgttaagg 39241 caaccttttt tattattggg gtgtgggctg agaaaaatcc cgatgaggta aaaatgattg 39301 cggatgaggg acacgacgtg gcaaaccatt cctattccca ttataaaatg tcgagcctta 39361 acagttcggc gataaaaagt gaaatattaa aatgtgacag agtattgaag aaaatcacgg 39421 gaaaagatgt ggaactgttc agaccaccct atggcgatta caacaatgac gttgtgagaa 39481 ttgcaagaga actgaatcac tatacaatac aatgggatgt tgactctttg gactggaagc 39541 ccggaattac tgctgaagaa ataaaaaacc gggtgcttaa aaatgtaaac aaaggctcaa 39601 tcatactgtt tcataatgat acaaaacata cagccaaaat acttcccgaa ataataactt 39661 cgcttaagca gaaaggatat gggtttattc ctgtttccca aatgattatg agggaaaatt 39721 atgaaattga ttacagggga agacagataa aaaaacagta acgcaagttt tttgccggca 39781 tttgcagtgt gatttttatc cttttacata aaattaagaa aaaagtacat tataaaatta 39841 cagtttatca aaagaaatgg ggtttgaacc gggtgctgat aacagcaata gttggacaaa 39901 atgacaaaga aaaaactgca aatgtcatta attccatatt acacaattca aagaagcgaa 39961 tcagcatagt tgactcaaag aatttgtccg gcttggacgg caaacggttg aaaagttatt 40021 tggcagagct ggagagaaat aatactgata ttcttattct gaaactggac ttaacagatg 40081 tttctaagga aatttatgac tatttgagat ttgatattat tgtttttact gataaagccg 40141 atgaaataaa tggagaaatt gaacaaaatt atatggattt gatgaaacgg gctttttcct 40201 tgctgaaaga aaaaggtata gccatagtaa atgctgatga taatgagctt aacaagtttt 40261 ttaaagacat taaacattat attgtcactt acggttttaa tctcaaggcc agtatgacca 40321 catcaagcat aggagacctt gtagccaagg ataacatgtt gtgttgcctg caaagaagaa 40381 tatatacaaa aaacggaacg gtaattgagc cgcaggaatt taaggttaag actgatcttg 40441 agagcgttga cccgaataat gttttggctg cggcaacctt tgttttggta aacggttttg 40501 atataaatca aatgaaaaac taaggcaagt cacacaaaaa tactgtcggg cattttcaag 40561 ttggtcgata tataatataa taatgattac gaatggtttt tggatattac agacaaagtt 40621 agaagatgtt tttttgtttt actgaggaaa tctaaaaagt ggatttatcc atgccggatt 40681 cctttcttta ggaaactgta attgagtttt attctgtata tttatataaa attattagct 40741 tctttcagga aatacctaca aatttagcta atgtgtgaat aaagtaattc taaaaagcat 40801 cattggtgaa taacattaca ttagataaat tattggatat acgtaagaag cctaagagag 40861 gagtgtgggg gtcggatggt cggaaacata attgagaaca acatggtgac catttccggt 40921 aagatagtgt cagaagcagt atttagtcat gaggtttatg gtgagggatt ttattgcttt 40981 acattggaag ttccaagact gagcgagtgt actgacaaaa ttaatgtcac ggtgtcggaa 41041 cgtctgattt cgaaggaaag tttgcaaata ggcaaattaa ttgaggtgga aggacaattc 41101 cgttcctata acaattatga caatcctgag ggaagcaagc ttatactgac tgtgtttgcc 41161 agagaaatcc gtttccttga ggatgataag aaaatcaaga atccaaatca aattttttta 41221 aacggcttta tatgtaaaaa gccggtatac agaacaactc cttttggaag ggaaattacg 41281 gatatattgc tggctgtcaa cagaccgtac aataaatcgg actacatacc gtgtatttgc 41341 tggggaagaa atgccagata ttcagccgga cttgaggtcg gccaaaacat aaagatatgg 41401 ggaaggatac agagccgaga gtatcagaaa aagctggata cgggagaagt tgtaacaaaa 41461 gtggcatttg aggtttcagt ttccaaaatg gaagtgtgtg ataaaataaa ccgaaaagtg 41521 gaaccaaaag aggagcagga ggaaaaacag gaggaaaggc aagaggaaaa gacggaagcg 41581 atgaaaaatt gattggtttt gtttttaata atgtttttta atgcgattta caaatagggc 41641 ggtaacgtaa aaaaaggtga tctgaagttt tgcagatcac cttttatgat gccgtttttt 41701 aattttaaac ttatcggaaa aggaagagct ttattttttg gtttcttacg aaatatctcc 41761 actgtctcat gagatacgga atcagataat aatccactcc aaaggacctt cccgcaccgg 41821 cgagcataca aattgcagcc gggatgaacc accaggaggt ctcatacagt cctgttgaca 41881 gcaggaagtt gatattcagt gccaatgcac ccaatcctgc taaaaatgta aatgttcctg 41941 aaataaacgc aataccaagg cctatttctg caagcactat aagccactgg aagaaaaggg 42001 cgttgggaat tacaagtttt tcggctataa aagcatacca cgaaggagta tgagatgata 42061 taattctgaa caccttttct ccggtttcgg tcacggaagc gctggtttga ccgtcaacag 42121 ccatgccggc aagcatagga gtgctgagcc agccttcttt taatttgttg agtccttcca 42181 taagccatga gtatcctaaa aagagacgca atggaacaag ccagaaagta ggactggtga 42241 cggagtagtg cttttccagc aggaatttat cctgtttctt ttggaaaaat tcgtgcctga 42301 tgtacttaaa tacaagctca aaaccgccta ttccaaacaa atagtgtata tttacgaggt 42361 atttcattaa tattgccaaa aaccttggaa gcagaacccc cataatctca gcaacggcaa 42421 agaaacttcc gacggaaacc atgacgccgt ggagcttggg ctttatttcc tctctttctt 42481 tgcctctgat atcattgagg acgtttaatg cagctccctt tccggtctgc agcgccgcct 42541 caaccagcgc cgggagagtg tgtccgttgt actcgaaaca agaggcatct cccactgcat 42601 atacattttt aaattgagtt gcggcgtatt tatccacctt tatcctacac gctcttcctt 42661 tttcaagaga aagattgtca ttaagacagc atgcccttac accggcagtc cagataaggg 42721 ttttggtagg tattttccgt ccgtctttga gctctacact gtcttcattg agcttgctta 42781 tcgcgctgtt caacagaaca tcaaccttca aagtgtttgt aagatacttc atggccttgt 42841 tgatattttt gtctttcaga ttgcttagta tctttggtaa agcctcgata agctttaagt 42901 caacttcttc tctttttata ttgtattccc tgcacaaaga tttgacccag tgagcgattt 42961 cgccgatggt ttcaacaccg gtaaagcctc cgcctcccac aacaaaggta agaagggtct 43021 tccttgtttc cggatctgtt gtccgggaag ctttatcaaa gcagtctttt atatgctctc 43081 taattgcaac ggcatctttg aaagaccaca aaggaaaagc gtattcttcc attcccggaa 43141 taccatagta attaggttcg cttcccaccg cgaaaataag gtagtcatat tggtactcat 43201 tggtgtcgga tataagtttg ttattctcca aatcaatatt ttttatttcg tctttaacga 43261 tttttacatc cgtatatgca aagatatctt ttaacggtac tatgacggca tcttcggtta 43321 tcctgtttcc cgcgacttca tggagttctg taagaagagt gtgataagga tttttgtcga 43381 taatggttat ttcgatatca tcttttttgc gtttcttttt gtggagcgtc aaggcagctt 43441 caatacctgc ataccctgct cccagtatta atactttgtg agccatccaa atcctccttg 43501 tatagaaata atctaaacaa ttattgtaat tgaacagata ttatatttga ttattttatt 43561 atttctttca ataaaaaaca ttaattcaac aaagtggaaa tagatataat aatttatacg 43621 ttgtgtaata catatattat ataccacgaa tttttatata taacacaaat tattcttgta 43681 ttagaaattt ttattttaat attaatttta agattaggct ttttataatt gacatatctt 43741 ttttcggtat aatataattt taacttgaac aaaagtttta tataaccttg gaagcattag 43801 ataaggatat ttgagaatat tggaataaat aaaattacat tgattgaata ataataatgc 43861 ttgtcaataa aatatggcat tgtttgctaa ttggtgatta tatgacaaaa agatttacgg 43921 taattatttt aagtatagtt ttgtgcacaa gtgttttgtt tgtatcatgc ggctataatt 43981 cttccgattt gtatgaaact caggaatttt taatggggac tgttgtttta cagaaaatat 44041 atcatgaaaa tgccgctgaa attgcaaaag aggtaaatga cagaatagcc gaaattgaat 44101 cgaccatgac aataaacaag cccggtgggg aaataaatct tttaaacgac gcagcgggaa 44161 aagaatatgt aaaacttggc gaggatactc tgtatgtgct tgacaaagca aaacaatatg 44221 cagagattag caatggagcc tttgacgtta ctataggtcc tttggtaaaa gcgtggggtg 44281 tttttacaga caatccgagg gttccatcga aaaatgaaat tgatgagctt ttaaaactgg 44341 taaattataa agatataaat attgactttg aaaattcaac ggctatgctg gcaaaagaag 44401 gacaaattgt ggatcttggc ggaattgcaa agggatttgc cgcggatgaa gcggttgaaa 44461 tatacaaaga acacggtgta aaatctgcgt tgataagcct tggaggcaac atttttacat 44521 tgagcggcaa acctgacgga agtccctgga tggtgggcat aagaaatccc agaggtaacg 44581 atggttcgta tatcgggatt gttagggtga aagacaaagc ggtagtcagt tccggtgact 44641 atgagaggtt ttttgaaaaa gacggtgtga gatatcacca tattttggac cccaagaccg 44701 gctatcctgc tgatacggga cttattggga ccactattat ttcggacttt tcaattgatg 44761 ccgatgctct ttcgacagcg gtttttgtgc tgggtcttga ggaaggcatg aaacttgttg 44821 aaagccttga tggggtggat gcggtgttta ttaccgcgga taagaaaata tatgtaacgg 44881 acggattgaa ggatacattc atatttaagg atgaaagcaa ggaatttgaa tatgttgaaa 44941 aaaggtgatt tctttatttt aggatttgtc ctgatattga taattgtatc ttttaccggt 45001 gtttaccttt acaagaattc gggttcaaat gctcataaaa tagcggttat tataaaagac 45061 aacgaggaaa taaaaaggat tgacatagat aatgtaaatg aacctttgga aatcagtgtt 45121 tcaggcgaat ataacaatat aatactggtg gaaaaaggac gaataaggtt taaggaagcc 45181 gattgcccag acagggtatg tgtaaatacc ggttggctta cgggaaaagg ggatacggcg 45241 gtgtgccttc ccaataaaac catgataaaa attgaggggc aatcgagtga cgtggacata 45301 gttacgtatt agtaatttaa aagcagtata atttggggcg gtatatttat actaaaacat 45361 cagataaaaa cataatgcta tgaggtataa atgtgaacag agtaaaaaag actgttttgc 45421 tggggttgtt tgtttctcag gctttgattt tgtcaatagt tgaatcatgg ataccaattc 45481 cctcgccggt gccgggagta aagcttggac ttgccaatat aataaccgta ataactatca 45541 tattttttgg atttagggaa gcagtttcgg tggtaattgc aaggtgtgtt ctttcatcta 45601 tatttggcgg agggggatgg atgcttttcc tgttcagtgt aacgggagga gtgcttagct 45661 ctgtcgtcat gtcgattctt tataaatcag gacgtgataa attcagtata acgggaataa 45721 gtatagctgg agcggtttcg cacaatgtcg gccagatatt tgtagcagct gtttttatga 45781 aagacctggc ggttgccgtg gttttgccgg tgcttttggt atcaggctgt ataatgggct 45841 tttttgtagg tcttgtaagc agttttttgg aaggtgtgtt gagaaaaaca aggatattcg 45901 attaattttt tctttaagaa gggatatgag aaaatgtcgt catcatatta tccagaaata 45961 gaaaaggaac ttgttttact tgaggaattt attcaaaaga atataaggtc cagaaaccgg 46021 cttttgaacg aggctgtaag cagtattgtt aagtcaggcg gaaagagact tagacctgcc 46081 tttgtcattc ttgcttccca atttggaaaa tataacagaa aaaaggttat tcctgctgct 46141 gcggcaattg aaattcttca cacggccaca ttgatacatg atgatgttgt agacaggacg 46201 aagtttagaa ggggacaagt tacaatatct gaaaaatttg gtgtagatat ggctgtgtat 46261 gtgggagatt atttgtatac aaaagctgtt ttgcttctgg ccggcaatgt tccggaaaaa 46321 aggctcagta ttcttgcgaa aggtataaaa gcgatatgtg aaggtgaagt tgaccaatat 46381 cagcacaaat attccattga tacatcggta tatacttatt taaaaagaat aggccgtaag 46441 acagcggtgc ttttcagtgc tgcatgtgct ttgggagcct atatcgccaa atgtccacag 46501 gaagtttcaa gaagtcttgt aaagttagga ctttattatg gaatggcctt tcaaataaag 46561 gatgatatca ataattacac aaaagctcag tacgaggagg ataaacctgt cggcaacgat 46621 attttggaag gaataataac tctgcctgta atattggggc ttaagctgaa acctgaatta 46681 agggaacctc tcaagaattt tctggataaa aaaggaaacg ttacagagga tgaagccgcc 46741 cgtgtggtac aattgattaa agaatcagga ggagttgaag aatcaagagt ttttcttaat 46801 aaatacgttg aaaaagcgtt aaaggaaatc caaaatcttc ctgataatga atataaaaag 46861 gcttttgaaa gaataatcaa agctttatga tagaaaaggg gcttgaaaat atctggaatt 46921 tatattattg tataattagg aggtaaaatt aatataatag gaaggataga tgctgatgat 46981 taaggttgtt tgtggcaaaa aggggtctgg aaagacaagg gccctggtgg actctgcaaa 47041 cagtttcgtg tcgacagctt tgggcgacgc agtttttatt gacggaagca gtcagctaat 47101 gtgtgacctc catcacaagg taaggttcat caatgtatcc gagtttccga tcgacatcag 47161 cagttcctgt acttttcttg gttttctctg tggtataatt tcaagtaatt ttgacgtaaa 47221 gtgggtatat atggacgatc tgatacgtat tgtcaggaag ccgcctcatg agatgaaaga 47281 gttgtttgac ggcttcaatg aactttcaga aaagtttaat gttgattttt atgtttccat 47341 tgaaggcgat cccgattcca tgcctgattt tataaaagtg tgttattaaa ggctggaaaa 47401 gggattttgt ttttgtacat ttttcccgtc tgaagatgct ccgaaagttt atgattatat 47461 tgaatttgta ttaagccagg gatattaaag ggtatctttg gctttttatt tggctttacc 47521 aaatgtaatt aaaaaagcaa aaagtgaagc gacttatgtg ttccaagttt ttgttatgcg 47581 ttgtttatta tgtgttataa ttatgtaata taatagttgt tggtgttcaa atggtgtaca 47641 atgtataata aaagatatag caaaaaaatt tataaaaggg tgccgtaatg aacaatattg 47701 cttcaattgc catcagcaat accacaagga aatttgacaa ggattatcac tatataattc 47761 ctgataaata tataggcagt atagtaccgg gtatgagggt gattgtgccc ttcggcaagt 47821 caaaccggct ggtggaaggt tatgtcctgg atgtgctgga aagccctgaa gtttcttcgt 47881 tgaaggagat aagcagggtt atagatgaaa agccggtttt gaaagaaaat atgataagac 47941 tggcatgctg gatgaaaaga cagtatattt gcacttatta tgatacaata aaatgcatgc 48001 ttccaccggg aacaggagta agcagtacaa aagttgtaag gctcaaaaag tgtgaaggcg 48061 gctttaaggg aaatattaaa aagataattg atgttttggc tgagtgtggc ggtgaaatgg 48121 aatatgaaga attaaaaaag caggtaaata ccaaaacctt tgcaaaatac attaataatc 48181 tgaaggagca aggttgtatt gaggtgcatg aagagtttac ttccaaagta aaggaaaaat 48241 acgttcgggc ggtgtacctt gcgaagcctt gggaggaagt ggtttatgat attgaaacaa 48301 acaagattaa gaatattaag catataagaa tacttgaact gctcgctgaa aatgagtaca 48361 ttccggtggg cgatattgtg cgctttgtcg gtgtgtcggc aggcgttctg gatactttaa 48421 aaaagaaggg atatttggag tttgaagata ttgaagttac aagggaccct gcagccaaca 48481 tgccctatga aagaacactt ccaatgaaac ctacgcagga gcagcaggtt gtaatagaca 48541 gagttaaaag catgctggat tcgggagagt ttaacgaagt tttgctgcat ggaatcacag 48601 gaagcggaaa aacggaagtt tatcttcaat tgataggaca ctgcattagt atgggaaagc 48661 aggctattgt cctggttcct gagatatcat taactccgca gatggtgaac aggtttaaag 48721 gaagatttgg tgaggatgtg gctgtaatgc acagccgatt gtccctgggt gaaagatatg 48781 accagtggag gcttgtaaga gatggcagaa ccaaggttgt ggtcggagca aggtcggcag 48841 tgtttgcacc ttttgataat cttggattgg tgattataga tgaggagcat gaaagctcct 48901 ataaatcgga aattgttccc aaataccatg cggctgaaat tgcaaggcag cgatgcatca 48961 tggaaaatgc ggtgctgttg tatggttccg ccacaccttc ggtggagact tattacaggg 49021 caaagacggg agaaattgag cttttggaga tgaccaaaag agccaacaac atgcttcttc 49081 ccgaagtaaa agtcgttgac atgaggaatg aactgaatgc cggaaacagg tctgtgttca 49141 gccgatgtct tcaaaatgaa atcagaaaaa atattgacag cggacagcaa acaatcgttt 49201 tcctcaacag aagaggctat gcgacgttta tactttgcag aaactgtggc tatgttttaa 49261 aatgccctta ttgcgatgtt tcgctgacgt accattccca tgaggagcgg gttatatgcc 49321 attactgcgg ctttacagta aagaacccgg agcattgtcc gaaatgtaaa agcaatcata 49381 taaggaactt cggcacgggt actcagaaga tcgaggaaga agtaaaaaag cagtttgagg 49441 gatgcacggt aataagaatg gatttggaca ctaccacggg taaaaactct cacgaggaga 49501 tactcaggaa attcagggat gacaatataa atgtaatggt tggaacccag atgattgcca 49561 aaggccatga ttttcccaac gttacactgg tgggagtact tgcggcggac agcattctga 49621 acaccggaga ctacaaagcg gcggaaagga cttttcaact gcttacgcag gttgccggga 49681 gagccggaag gggaacgatt cccggaagag ttataatcca gacttacaac acggacaact 49741 acagtattgt ctgtgcctgt gagcaggact atgtatcttt ttacaacaac gaaattcttg 49801 taagaaaaaa tcttcagtat ccgcctttta ttcatttggc atcggtgata ctgagcggag 49861 taaatgacaa acaggtgtta aacagggcac tttttgtcaa gaatgaactg tgcagacatt 49921 ttaaagataa tggttcaacg gcacaaattt taggcccatt gagagcacca ttggctaaaa 49981 taaaaaataa atatagatgg agaatagtaa taaaatgtga agaatcagat aaacttatag 50041 atgtactgac aaaagtttca gacggttatt attccaaaag cgcgaaaaat tctgttgctt 50101 taagtgtgga tataaatccg gttaatatgt tataatacat ctatattttt gtagactaaa 50161 caaatagatg ggggaaggaa aatggctgta agatttatca gagaagacgg agacgaaata 50221 ttaaggaaag tatcaaagaa agttgatgtt attgatgaaa gaataaaaac actgcttgat 50281 gatatggcgg aaacaatgta tgctgccaac ggtgttggcc ttgcagcgcc acaggtggga 50341 gttttaaaaa gagtggttgt aattgacgtc ggagacggac tgatggaact tataaaccct 50401 gagatagtgg agcaggaagg agaacagata gatatagaag gttgtcttag catacccgga 50461 gttgccggag aggtaaaaag accggcaagg gttgttgttg aagctttaaa tcgcgaaggc 50521 gaaaaaataa cggtagaagg taaagaactt cttgctgttg cattgtgtca tgagattgac 50581 caccttgacg gtattttgtt tacggacaaa gttatacgct ttattgatga ggatgaaatg 50641 gaaagaagaa gagaaaataa acgaagaaac aaaataagac aaaataaagg ataataatga 50701 aaaattatga atgacagata aaaagcggat tttcgcaaat gaggtgacag cgttgagaat 50761 agttttcatg ggtactccgg aatttgccat tccgagcctt gaaatgcttg taagagaagg 50821 atatgaagtg gcggcggttg tgacccagcc cgacaaaccc aagggcaggg gaaagaagac 50881 agccatgcct cccgtaaaag agtttgcaat aaaaaacaat attgaggttt tgcagccgtc 50941 aaaggtaaaa actcccgagt ttgtaagtac catccgggaa cttaggcccg atttgcttgt 51001 taccgcggct tatggaaaaa tccttcccca ggaagttctg gacatacctc cctatgggtg 51061 cgtaaatgtt catggttcgc ttcttcccaa atacagggga gcggctccga taaactgggc 51121 tattataaac ggagaaaagg ttaccggaat tacgacaatg tataccgatg ccggcatgga 51181 tacaggggat atgcttctta aggccgaaat agagatatcc gacgatatga cggcaggtga 51241 actgcatgac aagcttgcct gtcttggagc ggaggtactt agggaaactt taaaaaagat 51301 tgaggacagt actctccaga ggattcccca gccccacgag caagctacat atgcgcctat 51361 gttggacaaa actgttggat gtattaactg gtcaaaatcg gcaagggatg ttcacaatct 51421 tgtaagggga acaaatccgt ggccggtggc gtttacatat tataaaggac aaaaaatgaa 51481 agtgtgggtg acatccgttt tagatgaaga gaaccacaat tttacaccgg gtaccatttt 51541 aaaagtgggc aaggatggcc ttgttgttgc ctgcggtgtt ggaaaagttg ttataaaaga 51601 agttcagttt gactcttcaa ggagaatgac cgtagaggag tatatttgcg gacataaagt 51661 gggtgaaggt gaagtacttg gacaatagct atagaaattt tgcttcgtta atgggtactg 51721 tacttgtttt gtttgtgaca atattggctg ctttcggctt gttgtacagt tactcgacaa 51781 taaataccta taatttcata ttgctggttt tgatactgat tacagtaata gttacattgt 51841 tttattttgt atcttctata gctattatgt atgtttacag acgcaaaaaa gcaagcagaa 51901 ttgttttatg tatttcgaga acaggattga gaatgctttt tcccctggtt attgttttga 51961 ccgggttgtt tggtggaaat aaagacacaa taaagaaatt ttacattgat tttaacaatt 52021 tgctggtaga caccatggac aaaaaataca gtcctgatga aataatgata cttcttcccc 52081 attgtttgca gtattcagaa tgcgaataca aaataacaaa tgacataaat aactgcaaaa 52141 gatgcggaag atgctgtatt ggtttcattg ctgacatatc ggccgaaaaa aaagttccgg 52201 cttatgtggt taccggaggg acggccgcaa gaaatattgt ttcaaagaag gagccgaaaa 52261 ttattatttc cgtggcgtgt gaaagggatt tgagcagcgg aattgccgat gtggggagaa 52321 tacctgttat tggaatagtt aatgacaggc ccaacggtcc atgctataat acaaatgtgg 52381 atgttgatgc tataaggaat aaacttgaaa gcattataaa tgaaaaggag taaaaaggag 52441 gggtttgcta tgtatggtat cgatcaatat tatataattt tagttttgcc cgcacttatt 52501 ctttcaatat ttgcgcagtt caaggtgaaa agtacgttca ataaatacag ccgtgtcaga 52561 aatacaagcg gtatgacagg agcggatgtg gcaagactga ttcttgacag aaacggactt 52621 agtgatgtca ggattgaaag agttgcagga gaacttacgg accattatga tcccagaaca 52681 agagtgataa ggctttccca gtcggtttac ggcagcaatt ccgtggcggc aatcggagtt 52741 gcggcccacg aaacaggcca tgccatccag cacagtgaac aatatggccc cctggtttta 52801 aaacgcaatt tggttccggt ggcaaacata ggttcatgtt tgggattccc attggcgata 52861 gccggattgt tttttggttt gccttttttg gttaatttgg gaataatatt ttattctctt 52921 gcagtggcat tctacgtaat tactctgcct gttgaattta atgcgagcag cagggcaata 52981 cgcacccttg aagataccgg tgtgctgaat tatgatgaaa ttgacccggc aaagaaagtg 53041 ttgtcggctg ctgccttgac ttatgtcgct gctgccgctg ttgcaatcgg aaaccttctg 53101 cgtctgatta tgcttacgaa aagaagagat tgatggatat gaggacaaaa gtggacaaag 53161 taagggagac tgcacttaag atattgtacg atatcaatga aaagggagca tattcgaata 53221 tctccctgaa taaatatttg aatggccagg aatttgaaag tattgacagg gcgtttatca 53281 ctgacattgt gtacggtacg ttaaagtggc aatataccat tgattattta attgaaaagt 53341 tttcgtcagt caaaattaaa aagatttctc cgtggatatt caatattttg aggatgggta 53401 tttaccagtt gatttacacg gacaaaatac ctttttttgc tgcgtgcaat gaaagtgtga 53461 agcttgcggc aaagtatggc catgctgcca gcagcaaata tgttaatgct gttttgagaa 53521 atatagcgag aaacaaggag aatctgccgt atcccgacag aaacaatgat acggcacact 53581 atctttctgt aaagtattcc catccagtat ggatggtaaa ggattggctt gactgctttg 53641 gtgaggaatt taccgaaggg cttttgaaag ccaataatga agttgcaccg tttactgtaa 53701 gagtaaatga tttaaaaata tctaaaaaag agctggtgga tattttaaca aaggacggtt 53761 ttgaggttga aaacggcaag tatctggatg aagcactgat aataaggaat ccttcggcgg 53821 ttcaaaagat ggatgctttt gcgaagggat attttcaagt acaggacgaa agctccatgc 53881 ttgtggcaaa ggtattggat ccaaagccgg gagagacaat acttgatgtc tgcagtgcgc 53941 caggaggaaa gtccacccat atagcacaga ttatgaaaaa ccgtggtact gtgatatcca 54001 gagacattca tgaacataaa attaaactga tagaacaggc aaaagaaaga ctgggtctgg 54061 aaataataaa aactgaggtg tttgacgccg cagttctgga cggtaaatta atagaaaaaa 54121 ttgacagggt tttagtggat gctccgtgta ccggttttgg tataataaga aggaagcctg 54181 atataaagtg gtcaaaaaat tcggaagaca aggctgagat tgtgagcctt cagcataaaa 54241 tactttcaac ggcgtcaaaa tatgtaaaag acggtggtgt gctggtatac agcacctgta 54301 cgttagagcc ggaagagaac gaaaaagcgg tggaaaggtt tattgaagag aacaaggact 54361 tttatttgga agatataaca gagtttcttc ctgatgcttt aagaaaagaa agcgcaggca 54421 aaggatacat tcagctatat ccgaatatag acggaatcga tggatttttt attgcaagaa 54481 tgagaaaaag gagcaagtaa aatggacgca aaagcagacc ttctgagtat gacgatagag 54541 gaacttgaga atctgatggc tgaaatggga gagcaaaagt ttcgcgcaaa acagattttt 54601 cagtggacca ataaaggaat taaagatatt gatgccatga cgaatctctc aaaagactta 54661 agggaaaagt taaaggaaag agcatatata aacaggcttg aagtcataaa aaagtttgtt 54721 tcgaaaatag acggcacaat taagtatttg ttcaaattaa atgacggcaa tataattgag 54781 agcgtgctta tgcaatattt gcatggctat agtgcctgta tttcttccca ggtgggctgc 54841 aaaatgggat gcaaattttg cgcatccaca ggtgtcggat ttgtaaggaa tcttacgccg 54901 ggagagatgc ttgaccagat tctgaccata cagaatgata caaaaaacag aattggaaat 54961 gtagtaataa tgggcatagg agagcctctg gacaactatg aaaacgtggt gaagttctta 55021 aggcttgtaa atcacaagga cggtattaat ttaggggcga gacacatttc ggtttcaacc 55081 tgtgggcttg ttcctgagat tttaaggctg gcagaggaaa aaatacctgt taccctgtcc 55141 atttcacttc atgctccaaa tgatgaaatc agagaaaaaa ttatgcctat aaataaaagg 55201 tattctattg acaaaataat tgaagcatgt aagatatata ctgagactac taatagaaga 55261 attacctttg agtatgctat gattgacggt ttgaatgatt caaaggaaaa tgcgctggaa 55321 cttgcaaaaa gaatccgggg catgttgtgt catgtcaatc tgataccggt aaataccgta 55381 tcagataccg ggtttaagag aagttcgagg gaaaaaataa cggcgttcaa ggaaatcctt 55441 gaaaggtttg gtgttgaaac aactgtaaga cgcgagcttg gaagtgacat aaatgcggca 55501 tgcggacagc ttcgtagaaa ccttgtggaa aacggacaat tggtatatta gtatttgggt 55561 actttgaagc tggcgtaaag gtacaagact ttaagctaaa caggggagtg atagagtgag 55621 atttgcagcg aaaagtgaca ggggaatagt cagggagctc aatgaggata actataagtt 55681 gataacaggg tacgaagatg ttccggatgt ctttgttgtt gcagacggaa tgggaggtca 55741 cagttcggga gaactggcca gcagtatggc tgttgagttt gcggaaaagt acatattgga 55801 gcaccgtgaa ctgttctcca gtgaggaaag tgtactttca acaataaaag aactgatgga 55861 agaagcaaat acggtgatat ttaacagagc tgcagaatca caactaaact tcggaatggg 55921 caccaccttt attacagccg ttatgctgaa agataaaatg tatgtaggcc atgtcggaga 55981 cagcagggtg tatttgatca gagacggtaa aatagaaaag gttaccactg atcattcata 56041 tattgaggaa ttgattaaaa acggttcgct gacaagagaa gaagctgaaa atcatccaaa 56101 taaaaatatc attacgagag ccttgggctg tgaggaaaat attcttattg atacaattac 56161 cgttgatgta aaggaaaaag atatttttgt tttgtgcact gacgggttga caaacatgct 56221 gaaagaagat gaaatattgg acgtaattat gaaaaatgac gacccggaag tgtcatgcag 56281 tgaacttgtg cgattggcaa atgaaaaagg cggcgaagac aacattacgg ttattgtagt 56341 aataaacgac tgatggaaga atggcaaaac agcagggagt caggtgtaat ttgataatgc 56401 tatgaaaagc agaggtgctt aatatggttg gtcaaatttt aggaaatagg tatgaattga 56461 ttgagaaaat cggcggggga ggaatggccg atgtatataa agcaaggtgt aaattgttaa 56521 acaggtttgt ggcaattaag attttaaaac ccgaatttat aaatgatgag gaatttctca 56581 aaaggtttac aatagaggct caggccgctg caagcctgtc acatccgaac attgtctcca 56641 tatatgacgt aggccaggag aatgatatac attatattgt tatggagtat gtaaacggac 56701 agactttaaa ggagtacctt gacgagaatg gcgctcttta ctggaaagat gctgtaaata 56761 ttgcgattca aatatgtcag gctattgaac atgcacacaa aaatcatgtt gttcacagag 56821 atataaagcc tcacaatatt ttgcttacaa aagacggaat gctgaaggtt accgatttcg 56881 gtatagcaag agccgtaagt tcatccacta taaccatggc gggaaatgca ataggctcgg 56941 tgcattattt ttcaccggaa caggcccggg gaggatttac cgatgaaaaa tcggaccttt 57001 attcattggg aatagtactg tacgaacttt tgaccggaag agttcccttt gacggagaat 57061 ctcctgtggc tgttgcaata aagcatattc aggatgaacc ggaagagcca ataaatatta 57121 aagaggatat acccacgggt gttaacagta ttgttatgcg ggccattcaa aaggatcagg 57181 cattaagata tcaatccgcg tccgagttgc tgaatgattt gtacaaagtt ttgaaacagc 57241 ccgacgccca gtttgcaaaa gccagaacca cggaggacag tcccacggta agaattccgt 57301 caatcaagaa gaaagaactt gttctggaga tggacacatc gggaaaagca ggtgatgatg 57361 cagtgaaaaa gaagaaaaaa gacaacaaaa ccactgtatg ggcggtggta acatcaattc 57421 tggtgatttt cgttctgggc gccttgatgg taaagggctt ggggcctgtt gtttattcaa 57481 tgttcaacaa accggaggat tttattgttg aagattacac aaatcaaaat ttctatgagg 57541 taaaaggcaa attgtctcaa tacaatattg aggcaataga gataaggaag catgatgatc 57601 aaataccaaa agatagaata atttctcagg ataaagccgt tggggaaaga ataaaacccg 57661 gtgaatttgc aaagattgag tttgtggtga gtgacggtcc gttgcttgta aaaataccgg 57721 acctcagaag gatggaatac aggcaggcgg tgatagagct cagacaattg ggacttgaag 57781 caaatgtaat cgatgagtac agtgatgtcg tttcaaaagg tgttgtaatc aggacggaac 57841 cggatataaa cgcggaggta aaaccgggta cggttgtgaa tgtttataag agtttgggtc 57901 cggagataaa atacagcctg gttccgaact tgataggaaa gacaaaaagc gaggcattga 57961 accttttggt tggagccaag cttaccatgg gtaaaatata ccctgaagac atgacttatg 58021 ccagagataa aatagtaagg caggaacctg cagccggaac tgaagttgaa gaaggaactc 58081 cggtgaatat ataccttgag gattataatc ctgatcagaa atatgttacc cgtctcattg 58141 aacttgacaa tccggacaat tacggagaaa atataaagtt tttggtaaat ataacaagat 58201 cggatacaaa gagggttgag accttataca gtgaagtacg gaaaaaaagt gatttcccga 58261 taacgatttc cataccggta ccaaacggcg gaagtacttt ggtgagggta tatctcgata 58321 ataagaacta catggagttt acagaagagt ttaataaacg cagtaatgaa actaataccg 58381 gtaatactgc caacaataac ggtaattcca acaataacgg tagcggtagc ggtaccgata 58441 atattaatga taccaataat actgacaatg ccaacaacga taacgaaaga acggaagagt 58501 ccggtgaaac aaaccatgca gaagctgcag gatagtttta aggaggtata aagtttgcca 58561 tcaggtatta taatcaaagg tattggagga ttctactatg taaaaacgga gaacggaatt 58621 tatgaatgca aagccagagg cgttttccgt aaagattcca agattccttt acctggtgac 58681 gaagtagtta tatcggttat agatgaagaa aaaaagaaag gatatattga agaaatttgt 58741 gaaagaaaaa tacagttgat aagaccggcg gtggcaaata taaaccagat agctttggtt 58801 gtttcggtga aatcaccgtt gccggatttt gttcttttgg ataagctttt gataaccgta 58861 atgcaaaaag aattaaatgc gataatttgc ataaataaaa tagatttgga tgaaggatat 58921 aaggacgtta taatcgactg ctataaaggt accggagttg aaacagtatg tgtcagttcg 58981 gttttaaatg tgggatttga acaactggcg aaaatgctgg aaggaaagac tactgttttt 59041 gccggacagt cgggagtggg aaagtctacc atactaaaca aaattttgga ttcatatgtt 59101 atggagacgg gcgagatcag tgataaaatt gagagaggaa gacatacaac aagacatgcg 59161 gagcttttgg aactaaagtc aggagggttt gttgtggaca ctcccggctt tagttctttt 59221 gaactttcgg aaattgaacc gaaagaactt caaaactatt atcctgagtt tagagactat 59281 atcggcaaat gtagatttgc cggatgcagc catatcagtg aacccggatg tatggtcaaa 59341 agcgcattgg agaacggaat gataaacaag gacagatatg gccgctatat aatattttac 59401 aatatgttaa aggacaagca gcgacgtaag tattcctaag aagtttggat ataaagttaa 59461 tatataaaag tcaaaacttt tttattgatt gaatatgtgt tgaagctatt tttttggtat 59521 atatttggca tatatatttt ttgtttgtaa aatatattga atgtgcatag atttaattat 59581 ttgaaaggat gtgcttaatg ttgattaaaa ttgctccatc catactttcg gcggattttt 59641 caaagcttgg cgaagaggta cttcggatag aaaaagccgg agctgatctg gtacatatag 59701 atgttatgga tggacatttt gtacctaata taacaattgg tcctcctgtg gtaaagtcgc 59761 taaaaaaggt gtcaaagctg ccctttgacg ttcacctgat gattgaaaat cctgacatgt 59821 acatagaaag ctttgccgat gccggagctg atattatttc agttcatgcg gaagcttgcc 59881 gtcatcttca tagaacaatt cagaagatta agcagctcgg gataaaagct gctgtagcct 59941 taaatcctgc cactccttta tgtgctgtgg aatgggtgat ggaagatgtg gatatgattc 60001 ttcttatgac ggtcaacccg gggtttgggg ggcagaagta tataaacgga gtaacccgta 60061 aaatagaaga gttggaaagg attgtcgaaa gcagaggact taatattgat atagaggtgg 60121 acggcggaat agacactgaa actgttcaat acgttacaaa agccggtgca aatgtcatcg 60181 tgtcaggttc taccatattt gctgcggaag atactgcaaa aataattcaa gagcttagaa 60241 tgaactcgta caggaaatag gccggtgaag atatgatgta tgctcttgtt gtttgtaacg 60301 gaagcattat agattattca ttttacagaa aattttttga tgaagctgat tttattgttt 60361 gtgccgacgg tggagcttta catctgcaga ggctgggaat aaagccggat gttctgttgg 60421 gagattttga ttctatagaa agtgaacatc ttgaatacta catgaagcag aatgtggaga 60481 tattgaagtt tccggcggaa aaggacatga cggacacgga gcttgcggta aatacggcca 60541 ttgacagagg ttacaaaaat attgtgataa tcggaggcac cggtacaaga ctggatcaca 60601 ctttgtcgaa tatttttctg ctaaagctga tgcttgacag aggagtaaag ggcagaatca 60661 taaatgaata caatgaaatg tttttgatta atgacagtac tgagattgaa gccgaagacg 60721 gatgttatct tacactgttg cctcttactt caaaggtgga aggtataact acggaaggac 60781 tttattatcc ccttagggga gaggctattg aaatggggtc aaccagaggg gtaagcaatt 60841 gttttgttga aaaaaaggcg cggatatcaa taacatcagg tattttgatt gctataaaaa 60901 caagagaata aatattttga tgatttgatg aactgtaaaa aaagagaaga gctttgaact 60961 cttctctttt ttgattatct taaaatatct tctcaatttt tagtttatta ttttagcttt 61021 agctttttgt tttaaagaat acgataatct catgaatttc cgggtatggt tggtatgatt 61081 ttcaagacat aacgtttaag gtatgaatag tctgtagagt ttacccttcc gtctccgttt 61141 acatctgatg ctattaagct ccgttccgga tcagcggttg ggaaaacatc tatggacttc 61201 acaatatatc tttttaacag tgtaacatct gaagagttaa tttttccgtc cagattgatg 61261 tcaccgtaaa gaatatccga tgttggcgta ggtgaaggtg aaggatttac ggacggtttc 61321 ggcgttggtg ttgcaggacc ggtaccattg ggttctacac cgaatatgag aactccgtct 61381 tcataaacag gcatttcttt tacaacttca ccgtttttct tgattccctg ataggagaag 61441 tcgttggtgt tgtcccaagg tgcgcctgca ggaggctgta ttctaaattg ggtttctttc 61501 tggtggtctg agttgcttcc ggggaatatc ttggtaccgg agagatcgat ttcgcaataa 61561 tatatgtttt tggatgcgtc ataaagtatt ggttttgaaa tttttgcagt tggtgctgca 61621 ctgtaaatta tagaaacagt tatatcatta ggattgtatc cggcggatac atattccgta 61681 aggtccatga aatatctgaa ggaaagcttg tcgcaaactc ttgccggcca tccggattta 61741 ttgtaaaggt atgttttcaa ttcgacaccg ttatttgaat tggcggtagc ttcaacataa 61801 atttcttcat ttgttttttc ttctatagcc atgaagtttg gtatggggtt tccgccatat 61861 ttttcataca tcttggcgag caatcctaca aaaccggcat tgtagtcgca ggcaacctca 61921 tttgttacat agtttcctat atcatcaaca taagcatcgc tggcatcagg tccgcctacg 61981 agtgctccgt aaagaacgtg tctgtggtat tcaggaactt tttgactgtc acaccatgag 62041 ctgtgggcag ttctgtggtg cggatgctgc ggaggattta caccaaatcc gactacataa 62101 cttctgccgc tgctgcctaa ggcatagtca gcctgtttct tggcaaaatc tatgtaaata 62161 ttggcttttt cccttggaca ttctgaccag tcggaataaa cacatgcaag gaatgcagta 62221 gtagtggcat gtcttaatac accccagtca gtgaggtgag caagaccctt tggtgtatat 62281 ctgactctct gaccattaaa tccaactgtc caatagtcca ggtgtctttc tatcgcttct 62341 ttgtataagg atttgtttgt aatctttgcc aaaagaagtg ctgctccgta gtgaacgtcg 62401 tcccagcagt gaccccatga ataagcaatg taagttgtct ggctttcgat tggccattta 62461 tccacatact tttcagcttt ttcaagataa gtttcgtcac cgtctgcaag ataaatccat 62521 gcacctgccc aggaaagctc gtcataccat ccactgtgag atgtgtagaa attcaatgct 62581 gcggtatatc ctttatcact catagtggtt tcagcaaaat caaagagttc ttttgcatga 62641 cgtatgcaca gagcggcata tgccggatca gtgtctttga ataccaaggc agttgcagca 62701 agtgcggcag ctgtacccgc agtaactgtg gaaccgggat ttgacagatc tactttgtaa 62761 gacggtcttg gtgcctgaac atctatacat tctgccggca cccaccatct gtggtccatg 62821 tcaccgttac ccacttgata ataatataca tatttttcgg gatggcatct tatgaagtag 62881 tccgatgccc atttaatctg atccattaaa tagcccaatt gaccgctttt ttgtaacgcg 62941 tccttgtact catacacagc ccatgcaagc atagtggctg tgtaagccat aggcagattg 63001 aattttacat ggtcaccggc gtcaaaccaa cctcctgtga ggtcaagacc tacatcgctt 63061 ccgtctccga gacatgaatc accgcgccag ttgttacgga tgttgtcggg aagctttccg 63121 gacatttgaa attcatagaa cataattgct ttttggagtg cttctccata gttatagtct 63181 gctgcaaaaa caggcaactg cggtataaga gcagttaaaa ggacagcaga tactataaca 63241 gtgataatga gttttttcac tatatatctc ccccttttta aaatttgatt gttcacactt 63301 gtgttttgga taagcttcag aatagcgata ttgaaattca tgaattaact ggatatttgc 63361 gagtaaaata aatgcgaaca aatgattcta tttttaatta tatcataatt atatcataaa 63421 aattgtatca taaattataa ttttgctgat acataacatt cttgcggcaa tttttgctca 63481 attgaatatt aaaaatataa gaggcaaata acagggaatg attttgttta attctctgaa 63541 acgttgtctt tttatgtatt atcattgtct tcatgttata caggtaatat aatgtaatta 63601 taccggatat gtattttgca atacacgaac cttttaatgg gtaaagtcaa tgtaaaaatc 63661 aatctgaagg tctaataaaa aatatttttt cgaaaatcta tagaattata aaatgctttt 63721 gaaagttata ataagataag gcaacgggta aaaacacttt aaatgtgttg gaaaacgtat 63781 gataaacttg atttaaaaag gaggagtaag tttatgctgt atgacctgct gaaatccaga 63841 agaagcatca gaaaatttca aaacaaagaa gtggagaagg aaaaaataga tataatctta 63901 aaaagcgctt tgatggcgcc ttcgtcccgt tcgagaagac cgtgggagtt tattgcggtt 63961 actgacaaag aaaaacttga aaagctttca aagatcagag aacacagttc agattttttg 64021 gcaggtgctc cattgggcat cgttgttgtg gcaaatccga aaacttgcga tgtatggata 64081 gaggattcat caatagctgc gattataatt cagctttccg ctcagtctct cgggctcggg 64141 tcatgctgga tacaggtcag ggaaagattt ggacgtaaca ataagagggc aggggacatt 64201 gtaaaagaga ttttgcaaat acccgatgaa tatgaagtgg aatgcataat agccgtgggt 64261 tattccgcag aagagaagaa gccgtataat gtagatgaat tgccttataa caagcttcat 64321 tttgaaagct tttaacgaag aaagctttat aagaaaagac aaagacttcc ggctaatgct 64381 gccggaagcc tttttaagtc tttattttat aagattaaag tctttggcca atgcttcgaa 64441 agccggcagt gattttttta tggtatccat gcttacgcag taggagagtc tgaagtgccc 64501 cggtaaacca aagccggtgc ccggaaccaa aagaatgttg tatttaaccg catgtttgat 64561 aaattgtata tcatcttcaa taggggattt ggggaaaatg tagaaagttc cctggggctt 64621 tatgcatgaa aagcccagac gggttaaagt gtcatatatt aaatcccgcc tttgtttata 64681 gctttcaaca tcaatatccg catccagaga gtcggcaatt gccttttgga acaatgcagg 64741 agcattgacg taacctaagg tacggttgca gaatatcaag ctttccaata taagttccag 64801 ttcgggaatc tccggattta ccgcaatata accgattctt tcccccgcaa gagccaggga 64861 tttgctgaaa gagtttacga taaaggattt tttatacagt ctgaaaagaa aaggaagttt 64921 tacattgtcg taaaccagct tgtagtaagg ttcatcggaa attgcatata tactggaatt 64981 atattccttt tctttctttt caagaacttc aaaaatctcc ttcagggttt cttcgctgta 65041 tatgtaaccc gatggattat tgggagaatt tatgattatg gctttagttt tttcggtgat 65101 gctgttttca agtattttta agtcaggttt aaaactgtcc ttttccggtg gtactataac 65161 cacttttccg ccgtgatttc ccacatagaa tatatactct gcaaagtaag gtgccagtat 65221 gatgacttct tctccggggt tgagaagagt tttcagtaca acgttgagag caccggcagc 65281 gccgcaggtc atgattatat gctgagatga tatggaagac agcccggagg ttctgttcag 65341 atagtctgcc actttttgtc tcacatcttc atatcctgcg ttattcatat aacggtgtat 65401 gcccggtttg tcttcggtaa caattttttt aagtgtttct tttaccgaag agggcggttc 65461 gtggtcggga tttcccaaag taaaatcata aacgttgtcg gccccgtgaa ttttacgaag 65521 tttttctccc tcttcaaaca ttgcccttat ccaggaggct ttctttaaac tgtttacaac 65581 actttctgat atcatttact aacactcctt atctattttc cattcttaaa ttattgacta 65641 cattttcatc aggtgtgaca ataatagttt tataattatc gtagattacc attccgggtt 65701 ttgcaccgtt aggttttttt acatttttga ccttggtgta atcaacctcc acatgggaag 65761 aattctttgc cttgctgtga taagccgcca gcatggctgc ctgaaacagg gtgctgtcgg 65821 gtatttctcc tctatctttt cttattatga catgagagcc cggaatattc ttcgtatgaa 65881 gccagatgtc attggaagat gcaaatttca atgtcaaaaa atcattttgc acattgtttt 65941 ttcccacata gatataaaaa ccgtctgtgg acttgtaagt ataaggagta aagttttttg 66001 aatttttctt ttccggcctt tttttctttg aaggcaaata cccttgttcg gcaagttcct 66061 gccgtatatc gtcaatatct tcgaaagaat tgctgttttc aaggctgtga agcacacttt 66121 caagatatga aagttcgccg cgggcttctt caagttgctg tgtggcatga atgtaagcgg 66181 cttttgcctt tgcgtatttt ttaaaatacc tctgggcgtt ctcctgagga aggaggtttt 66241 cgtcaagagg tacttcaaca tactcgccgt tttcgctgta gtagttcaaa agtgaaactt 66301 tgcttgcatt tttaggtata caatatatgt ttgcagtgat aagctctcca tagagtttga 66361 acttttccct ttcggcaact tctctaagtg tgtccatgtg gatggatatt ttcttattgc 66421 agcggtcaat gcagttgttt aaaattttcg cgagatctgc cttcttctgt gcaagtctct 66481 cggaagtatc tttgatcgta taaaacaaat ccaaaactct gctgatggat ggataaaaat 66541 ccaccgtatt atattgtttt atttccaaag aatggaaatc tacggctttt ttgcctgtca 66601 tcaccgttcc atattataca tggtgtaaat tctgaattct caatttttga aattatttct 66661 ttcaatactt tctttaagtt ttgaatagta tcctctgaaa ggcttgaaac cggcaatcga 66721 gggtcaacat ccgcacgatg gcatatttct tcacataaaa ggggactgaa tcctttgata 66781 ttgtttaaaa agaactttga aatacgggga tccccttgtt cctttgcttt tgagaaaagc 66841 aaatcaatat caagctccag aggattgatt ttgtcctggc cgggaggaag ggtatagggt 66901 cttgccggca tgacttctct tacccggctg atatcactgt ctacatgctt tattgaatca 66961 attattttat tttcattgtt tacaagtata atgttgctat gtttacccat tatttcaacc 67021 acaagttttt taaaagtcaa atcacccaat tcgtcaatgg tttctatatg tattgtaaca 67081 actctttcaa agtcatgaaa atctattttt gttatctttc ctcctgaaag atgctttctt 67141 aaaagcatgc aaaaaacagg agggtttata ggattctcct ttgtaacgtc ggtaagatga 67201 atccttggat agcttgcatt ggcggataat aaaagtttga ggttttggcc ttttgttctt 67261 aagtttatta ttatctcatc cggctcgggc tgataaattt tttctattcg ggcgcctgta 67321 aggatgtccg acagttcgct gactatgttt ttggttacta taccgtcaaa aggcaaatta 67381 ttacacctct tttgttaaac atttttatta taattttatt ttataattaa tttgaaataa 67441 aaatttctta aaataaaaat ttaaagaaaa aatttaaagt aaaaatttaa aacaaaaatc 67501 aattaatggc aaattaaagc tattagaaat atatgaatat ataaaacaat agctttaatt 67561 attttccttt gaatatcata ccacttggaa agatttttaa caacataaaa tgtgattgga 67621 gatatttaca tattattttt gcatgctgtt ttctttatat atggggaatt ttattataaa 67681 tttgctgcct ttcatttctt cggattctac ttctattgta ccgttaaatt ctttgacaat 67741 tccgtaactt attgacaacc cgatgccggt accttttcca acttcctttg tagtaaagaa 67801 aggctcaaag attttattga taatggattt ggaaatacca attccgttgt cagtaatttc 67861 aataatgaca tgtttattat ccgaaaaggc ttttatagtt atttttttat ccggggggac 67921 aatttgtccg tcagcgtcat tttcggatac caggcgttgt tggacttttt cacgttcatt 67981 caaggcatct tttgcattta taataagatt taaaaaaacc tgttccagtc tgttatgatc 68041 ggcaagaaca tatggaaggt tttcttcgat gtccatatca acactgattt gttgtctttt 68101 cagctgttcg ccaataagtt tgaacacgtc cgtgagaggc attttaatgt ttaccggtgt 68161 tttagtttgg tcggattgcc ttgcaaaggt gcgaaggtgt ccgattattt tatcaatacg 68221 atccacctgc tctataatgg cgttgagctt ttcgagcaac atttcatcgg tcagtttatt 68281 ccgctttttt gccagaataa gcccctgggt aatcagactt atacctccca aaggctgatt 68341 tatttcatga gctataccgg tggccatttc ccccagagtg gcaagttttt ccgactgtac 68401 cagctgtgcg tctttttcgc gcagctcacg ggtcctctcc tttaccattt tttcaagatt 68461 gtcggcatat tcctttattt cttctatcaa gcgttttcgc tgaatccctg ttgttatttc 68521 attggcaaca aggcttaaga tttggctttc tttgagaaga aaggttttct gaggttcaga 68581 aacaacaatg tgaagtattc ccatgattga aacgtccgat atcagaggaa tgtgaattat 68641 gaagttttca cctctgccgg gtaaatgtgc ttccatgtat tcatagatgg catgttccga 68701 aaggggagag tggtttattg taagctgtgt gtaagttttg aagcagcctt ttatgttttc 68761 cgccacatct ttggcgcagg tatggtagcc gcaggtgtgt ccggtgcagt ttttgcacaa 68821 accagtcatt gcatttatgt aaaaaaagtt gccaggacgg tcaaaaagac aaataaatac 68881 cgccggcaag ccgaggaagc tgcttatggc attgcatacc tcggaacaca tctggtctat 68941 ggaggatgat gaatttataa gatgtgtgat ttcaatcagt acactgttga attggtccaa 69001 aagcttgtat cttgtaatat ctctggtaag aatcaataag cccagtgttt tgttgttttt 69061 gttgactctg ggggttgagg taatggaaat ggggataaaa gttccgtctt ttcttttggc 69121 atacattgtt tggtctatca ggcgcgattt tgtttcattg ttgggtacga aaagaaattc 69181 attgtttggc aaaccttttc tgtgaaggtc gggaggaaac tgctttccca gcatttcttc 69241 ctttgagtag ccgtaaatga gttcagcacc cttgttccag ataattatcc tgttgtggat 69301 gtcagtagcg ataatggcat attccgttga gctaataacg atgctttcca atatgtcttc 69361 cggaagattc tcattaatgt gcagattttt cctcattttg acctccagtt gacctccaaa 69421 atttcaattc tcttttaaga cttcaacacc taatatcgtc atgtcatcag tacacctatt 69481 gcccgagaaa tcttttacgg ctttcattat tttatcaatg gtagttgaaa taggttcatt 69541 tttgcagctt tcgagaactt taaccatgtt ttcatagccg aaaatttgat tgccgtcaga 69601 actttcatca cttgaatccg aaggactttc aataatgccg tctgtgaaaa gcaatacttt 69661 gtctccgggt tccaactggt ttacagcaca tttgtaggtt gaatcttcaa agactccaag 69721 aataggtcct gttgattcca acggcaccaa tccgttttct ttcattatgt actgtggaat 69781 atggccggcc gatacagtat agagcttttt gctgttttta tcaataaagc ctaaaaacaa 69841 ggaggcaaac acattttgcg ccgtattgga cagaagttcc agattcaaat ccaaaactat 69901 ttcaggaaat cttctcttgt tgattccctg acgatagttg tattctatat tttgaagaaa 69961 actttttatt attattgaaa taacggcggc aagaatgcca tgatgggata cgtcaaaaac 70021 ataaaaacat atataatctc ctatatcaca cacatcgtac atgtcaccgc cgacaccgtc 70081 acagcttttg tagtccacgg caaagttgaa gccctctata tccggcaggt tttttggcag 70141 catgttgagc agtatttttg ccgcagaatc atgaagacct tgtaaatagt ttctgtgagc 70201 cagcaattcc tgggtcattc tttcattttc catgagaagt ttctttctgt ttatggcgtt 70261 atttatagct attgataaat cctgggctgt gaccggtttt ctgagatatt caaaagctcc 70321 ttctttcatt gcaagaattg cattgtccaa gtcaccgtgc cccgtaagga tgattacggc 70381 catatgaggc gtgatttttt taatttctct tagaatgtcc atgccggaca gctttggcat 70441 tttcatgtcg gtaatgacaa catcgatgga gttgcagttt tctgtaaaaa tcctgagtcc 70501 ttctgtactg ctggaagccg tcagtacttc attgccgtca atttccagaa gaaatttaat 70561 gttctgaaga atggtacttt catcgtctat tacaagaatc tttgccattt tccttactcc 70621 tattcagtat tacttaatta ttatagcaag ttttatatga attttctata atcataaagt 70681 ttgtgttata atagtaggag cggcatggac ataaaaattt tattgtaggt gatgtttatg 70741 gttgtaggtg tttgcagagt gattttaaat attaatgaag ctttttcgct gaaagagaag 70801 agacaggttg taaaaagtat tgttgaaaga gttaagtcga gattcaatgc ttccgtggcg 70861 gaagtggggt tcaacgacaa atggaaaaat gcgataatag ggatatcctg cgtatccaat 70921 gaggccggac atacggacag tatgatggcg aatattgtga attttatcga aaatgacggc 70981 agggtagaat tggtggacta cagcactgaa aatatatatg tggattaatt ataaaggtta 71041 aagttttttt atttttccaa aaaagactat tgaattacgg gaaaaaatat attaaaatat 71101 gtattgctgt tgttaatatt ttggggctat agcgcagttg ggagcgcgct tgaatggcat 71161 tcaagaggtc aggggttcga acccccttag ctccaccagg attataaggc agaatgggtt 71221 attacctgtt ctgcttatta tttttttccg gaattttttg ttatgaagta aaaaacggtg 71281 taacactttt ttaattgttt gaatactatg ataccgtgaa gcaaaacaaa ataggaaagg 71341 atgagaggta tggaggagaa tagaggtttt ggctgctttt atggtaatga cattatttgg 71401 ttgataatta taattttgtt tattctgtgc ttgtgtccgg gaattttcgg cggttttggc 71461 ggatgcggct ataagaattg accgactgca tgtacataag aatctaaaga ggggaggtaa 71521 ttgcctcccc tttttgttat aatagggata tgcggggaat taactgagtt gatgggagta 71581 attttattta taagtttatg gtttgtcgat gtggagtagt gtaaaaaacc cgggagatcg 71641 acaaagtttg ttgatgtctt ttaaatgcag gattatgaat agtttgagtg atttttttta 71701 tttttgttat tgatttttat tttatatgtt attaaaataa aaagtaggaa ttatgcaggt 71761 tctatggggt ttgtatcgta cctatgagga attgaaactt cttcaggaag tgagtaaggg 71821 taataagggg gatagtttgt atcgtaccta tgaggaattg aaactgctca gaatatggct 71881 aggcatttac acgtttgatg ggtttgtatc gtacctatga ggaattgaaa ctgttggatg 71941 ccatacggag aggcgcattg gattttggtt tgtatcgtac ctatgaggaa ttgaaacata 72001 atgacattta tggtactgtt gtggtaatag acgagtttgt atcgtaccta tgaggaattg 72061 aaactagtgc atctttggaa gacgaatgaa gaattcagag aagtttgtat cgtacctatg 72121 aggaattgaa acaacctctg tttttcgtcg tcccagtatt ccttccttgg tttgtatcgt 72181 acctatgagg aattgaaacg gataaacatt cagaactact ctttcaaaat actcagtttg 72241 tatcgtacct atgaggaatt gaaacttaaa cccacttttt tgaatttatg attatgtatt 72301 agtttgtatc gtacctatga ggaattgaaa ctcgcctctt tggtatttcg ggcgtaaact 72361 gcaaagacgt ttgtatcgta cctatgagga attgaaacat atttaggcta tactcaccgg 72421 cattcagttc cattagtttg tatcgtacct atgaggaatt gaaacctggt attcaatgtt 72481 cttgcaaaat tgttccattc agaagtttgt atcgtaccta tgaggaattg aaacccgatg 72541 actctctttg gttgcttgac gatagtcaga aagtttgtat cgtacctatg aggaattgaa 72601 actcatagag tataaatcag ccaaatcatt cctagcaccg tttgtatcgt acctatgagg 72661 aattgaaact actaacgtgt accgtataac cgactataaa aatccgtttg tatcgtacct 72721 atgaggaatt gaaacaagga taatagttgg gtttttgtac atagtgtatg ggtttgtatc 72781 gtacctatga ggaattgaaa ctatacgtag ctcccagaat ctgtttgaac tctgtaagtt 72841 tgtatcgtac ctatgaggaa ttgaaactaa aacaaacttc tactgccact ggtcggattg 72901 ttcgtttgta tcgtacctat gaggaattga aactagaaat tgggataagc agcttttaga 72961 attgccatgt ttgtatcgta cctatgagga attgaaacat gtggaggtgg cggtatgata 73021 tgtatagggc tagagtttgt atcgtaccta tgaggaattg aaacaaagtt taaaccctgg 73081 acgttgtatg tttgcgcctg gtttgtatcg tacctatgag gaattgaaac aataccccaa 73141 aatgaaggtt caagtcattc gaacaacgag tttgtatcgt acctatgagg aattgaaacc 73201 caattttgtc tttgtcctcg tcaacacctt gaccaagttt gtatcgtacc tatgaggaat 73261 tgaaacttaa atgatcctcc ggtaacacta gaagccggaa cagtttgtat cgtacctatg 73321 aggaattgaa acagctatac catatcaata cagatcttgc accgtgatag tttgtatcgt 73381 acctatgagg aattgaaacc acttccggga tggtagtcag tgccatcggg cttgacatgt 73441 ttgtatcgta cctatgagga attgaaactc gttcagcctc cctatgctac ataccggatg 73501 taatgtttgt atcgtaccta tgaggaattg aaacccgact gttcgacgta gacgtcgaca 73561 ggaggaaaga gtttgtatcg tacctatgag gaattgaaac ttgcaagtca ggtaatgcct 73621 tttgataccg gtaccatggt ttgtatcgta cctatgagga attgaaacaa gacactgaga 73681 ctctttctat tagtattgat ggaaacgttt gtatcgtacc tatgaggaat tgaaactgta 73741 aataaagcta tgaaattgaa tgattatatc aggtttgtat cgtacctatg aggaattgaa 73801 acagcaacag agctacgagt taggagaaat gcccgtaggt ttgtatcgta cctatgagga 73861 attgaaacat tgtattgact tgaacactac caactgataa tgaaggtttg tatcgtacct 73921 atgaggaatt gaaacgagta taaggctaaa tggtatggca gaacgtacca cgtttgtatc 73981 gtacctatga ggaattgaaa cacattcaac accagctttc tgccctatga ccaacctatc 74041 gtttgtatcg tacctatgag gaattgaaac gccaacgttc taaaaattca catactctta 74101 ttttttctgc tcgtttgtat cgtacctatg aggaattgaa actcctcaat ctgtttttct 74161 gtaaacatcc actaatacgt ttgtatcgta cctatgagga attgaaacat ccaaggatgt 74221 tgaccaatga tagtttcatg tgatagtttg tatcgtacct atgaggaatt gaaactcaat 74281 gaccaagagt gaaattgcga aaatacttgc gggtttgtat cgtacctatg aggaattgaa 74341 actggcccat actacatacc acggtggcta gaaaaggagt ttgtatcgta cctatgagga 74401 attgaaacag aataggcaca atcggaagtg aacaaggaga aatagtttgt atcgtaccta 74461 tgaggaattg aaacttgcag atactacatc ggctggtata tcttctggtg gtttgtatcg 74521 tacctatgag gaattgaaac ttagtttata gggagatatt gaatctccct ataataacgt 74581 ttgtatcgta cctatgagga attgaaacac aaggcgggaa tgggtgaaca ctttacaact 74641 gtatggtttg tatcgtacct atgaggaatt gaaacagttt ccggcatctc atcccaagtc 74701 cgttcatcca aagtttgtat cgtacctatg aggaattgaa actaagttgg gcttctaata 74761 gaagttctgg tgctgttgga gtttgtatcg tacctatgag gaattgaaac cttgattttg 74821 attttcaagc ggattatgct tcaaaaaagt ttgtatcgta cctatgagga attgaaacta 74881 ttaccatagc caagcggcgg taaatatctc acatgtttgt atcgtaccta tgaggaattg 74941 aaattgtaat agcatcgaca ataatgttgt cttgattcag tcgtttgtat cgtacctatg 75001 aggaattgaa atttctggct actccaagtt cctaatgtta tatatggttt tatagtataa 75061 agccttaagc gaaaatgaat aggactgtat aataaggtta aggctttata ttcgcctgaa 75121 gcgtaaaaac gcaataggaa gaataaaatt tttgccgggg ataggccagc cttgcaaact 75181 ggctgacaag cgaagtctcc ccgcttcccc ggcaacaatt tcaaataggg agacagaaag 75241 ggagacgaaa tatggaatct atgaaaggga aagtcattcg ggacattagg aaccaggaag 75301 caaaaagaaa gcaactccaa aaggagatct tcaaccagcg gtacaatgct acgaaagagg 75361 cgaagttcat agacaaggag gatataaata tgaatagctt ccgggctatt cctaaaagcg 75421 tgatacaaga gctaggctta tcgaaagcgg ccctggctat ctatcctgtc ttatgtgcaa 75481 aagcagattt tgaaaaaaat aactcttttc caatatcgca gaaaaatatt gcccgctttg 75541 caggagtgag cgagaacagc gtccgcaatg ccttgaagga attggagaac gccggactgc 75601 taacaaaaga aaaggttaca gatggccccc gccacttcta cgtctataaa gtgacctttt 75661 atcgtaggcc tgagctagaa gcaaacgaac aacgtgggga tgcaatctat ttttataact 75721 gcattattga taacggaata tgggctgagc taaaaccaag gacgaaggtt ctttatttga 75781 ccctgcgtgc tgtcgcgaag caggatattg aactatattc tgttatcgaa ggggagaatt 75841 acggtgggga ttggaacggg gttaactacg atgattatat ccgcaaccgt aaatgggacg 75901 tctgcgatat ttccctttct aaactctgta agctagctaa aattgaacgt acgaatctaa 75961 ccccaatatt ggaggaacta gaacgatata aattgattga gagggttgga gagtggacga 76021 aag //