LOCUS NZ_ACVX01000023 61141 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00060, whole genome shotgun sequence. ACCESSION NZ_ACVX01000023 NZ_ACVX00000000 VERSION NZ_ACVX01000023.1 GI:256005060 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 61141) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 61141) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000023. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..61141 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene 27..1808 /locus_tag="ClothDRAFT_1892" CDS 27..1808 /locus_tag="ClothDRAFT_1892" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: conserved hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430031.1" /db_xref="GI:256005061" /translation="MKYKIFTIIIFIFITFIMVSCNNNMKNITTSPDNESTPNSSATD NLTIDNFTTDNSSKSEQLISKKDIDEYFNLYYNYFKEQKIENSNYTDSSFFRYSLEFP TVFFDKVTLYFANNSERLTPSYIEISVPYEIEALRDFGFKKGMSLNDVNQIDKSLKIE ECKISHSDNNISFIELKIGNYIYILTASDSEEEIVDVYIKKDGTNLIDAVYNDIVNLI ADFSDYDNCYPLFLTRGNINHDSYEDVIITFEIDTPQDGIESYGNSRVTLILFGSKDG YLKYGEVEGLITSHGGLLGKPIVSTNIDNGTISISQYGGSAWRWNVISTYQYDKTDKR IYLTKQEESHYYNVLPMQDTLQTIVNHFEEKIDILDNFYENNQKSNTVSKTLGKLIIS YEEFNYSDNIKQNFINDTIKKYINKQIEKIKNMGVEGKFSITVGETIKNEKFASICIY TNGNYYNHSKEIKNDEYNEYFHDEEYVNIDLVNLKEVDIFNYYTIDEIAQKLYDVHVE QGNPEDYSVKSKEDIVNVIKDSMNGANKGNNKFEYYFNDLSIRLVLYLQNKNEDIVDE RECSVLRTDELVVKPTLFKEWFDSKLQ" gene 2110..2889 /locus_tag="ClothDRAFT_1893" CDS 2110..2889 /locus_tag="ClothDRAFT_1893" /EC_number="2.7.7.33" /inference="protein motif:TFAM:TIGR02623" /note="KEGG: glo:Glov_0782 glucose-1-phosphate cytidylyltransferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase" /codon_start=1 /transl_table=11 /product="glucose-1-phosphate cytidylyltransferase" /protein_id="ZP_05430032.1" /db_xref="GI:256005062" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR013446" /translation="MKVVILAGGMGTRISEESHLKPKPMIEIGEAPILWHIMKYYSYY GYNDFIICCGYKGFLIKEYFANYYLHLSDVTFDFSRQNNMIIHNNIAEPWKVTLVDTG LCTQTGARIKRIQKYIGNESFMLTYGDGLSDVPLNELVNFHRKHGKVLTMTAIQPGGR FGVLSFGEDDYTIEKFSEKAKEHGGWVNGGFMVAEPEIFEYLDYRDDLVFEQEPMHKL ASGGQLAAYKHFGFWQCMDTMRDKIMLERLWSSNSAPWKVW" misc_feature 2116..2880 /locus_tag="ClothDRAFT_1893" /note="G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524" /db_xref="CDD:133015" misc_feature order(2125..2136,2176..2181,2422..2424,2437..2439, 2488..2496,2671..2673,2740..2742,2818..2820) /locus_tag="ClothDRAFT_1893" /note="substrate binding site; other site" /db_xref="CDD:133015" gene 2965..4104 /locus_tag="ClothDRAFT_1894" CDS 2965..4104 /locus_tag="ClothDRAFT_1894" /inference="protein motif:TFAM:TIGR02622" /note="TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: sew:SeSA_A2324 CDP-glucose 4,6-dehydratase" /codon_start=1 /transl_table=11 /product="CDP-glucose 4,6-dehydratase" /protein_id="ZP_05430033.1" /db_xref="GI:256005063" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR003869" /db_xref="InterPro:IPR013120" /db_xref="InterPro:IPR013445" /translation="MKNFYKNKRVLITGHTGFKGSWLSEILLQFGAEVCGYALESKES SDLYLNLKLHKNMNSYIGDIRNYDKLKKVFDTFKPEIVFHLAAQPIVRESYKNPLYTY ETNVMGTVNLLEAVRHCSSVRSVVNVTTDKVYKNINVNKGYTETDYLCGQEPYSNSKS CSELVTYSYKKSFFDTDDSPAVSTARAGNVIGAGDFSKNRIIPDCVRAAFSRNKIEIR NPYSIRPYQYVMDCLYGYLLIGMKQYCDRSLAGAYNFGPKEDDCKTTIEIVDKFCHVW GDGLDYYTKPDDSVYESQILMLDSSKSNKLLNWNPQYDIDHAMHKTVELYKLIYEKNF DEYACSHIEDFFSGVSAFKNNSPLSISAKKSAKNNSLHENQICAM" misc_feature 2974..3999 /locus_tag="ClothDRAFT_1894" /note="CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622" /db_xref="CDD:162953" misc_feature 2980..>3393 /locus_tag="ClothDRAFT_1894" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" gene complement(4132..4680) /locus_tag="ClothDRAFT_1895" CDS complement(4132..4680) /locus_tag="ClothDRAFT_1895" /EC_number="5.1.3.13" /inference="protein motif:TFAM:TIGR01221" /note="KEGG: pca:Pcar_1129 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related" /codon_start=1 /transl_table=11 /product="dTDP-4-dehydrorhamnose 3,5-epimerase" /protein_id="ZP_05430034.1" /db_xref="GI:256005064" /db_xref="InterPro:IPR000888" /translation="MMLDIKESKIIGCYELIPRIFSDNRGRFVKTFHEEVFAQAGLET NFAEEYYSVSHKGVLRGLHFQKPPREHTKVVYCVHGEVMDVVVDLRVGSPTCGKYDIF DLNSDKANMIYIPKGLAHGFYVKSNQAILIYKVTTVYSPENDTGIRWDSVGIPWPNDN PIMSERDRMLPAFEEMQNIFTY" misc_feature complement(4153..4668) /locus_tag="ClothDRAFT_1895" /note="Cupin domain; Region: Cupin_2; cl09118" /db_xref="CDD:186830" gene complement(4818..6191) /locus_tag="ClothDRAFT_1896" CDS complement(4818..6191) /locus_tag="ClothDRAFT_1896" /inference="protein motif:PFAM:PF01041" /note="PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: gur:Gura_3788 DegT/DnrJ/EryC1/StrS aminotransferase" /codon_start=1 /transl_table=11 /product="DegT/DnrJ/EryC1/StrS aminotransferase" /protein_id="ZP_05430035.1" /db_xref="GI:256005065" /db_xref="InterPro:IPR000653" /translation="MNPDINAKEKELLREIHQAVVKYYNFKHKKEDKPYNPGDRIPYG GRVFDENDIINLVDSALEFWLTTGKYSEQFEKDFAEFLGVKTCSLTNSGSSANLLAFM ALTSPKLGDRRIKRGDEVITVAAGFPTTVAPIIQYGAVPVFVDVEIPTYNIDCSRLEE ALSDKTKAVMVAHTLGNPFDLETVKNFCDKNNLWLIEDNCDALGSKYFYNNEWRYTGT IGDIGTSSFYPPHHMTMGEGGAVYTNNTMLKRLIESFRDWGRDCWCASGKDDTCKNRF SQQFGELPYGYDHKYVYSHFGYNLKVTDMQAAIGCSQLKKLPQFIEIRKRNWNLLKDG LKDLQDVFVLPEPTKNSDPSWFGFILTVKENAGFTRDEIVSYLESKNIQTRMLFAGNI LKHPCFDEMRASGEGFRVAGNLSNTDKIMNNTFWVGVYPGITEDMCGYMVEQIKSFVN SKLRRKL" misc_feature complement(4836..6176) /locus_tag="ClothDRAFT_1896" /note="lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407" /db_xref="CDD:185305" misc_feature complement(4854..6035) /locus_tag="ClothDRAFT_1896" /note="3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616" /db_xref="CDD:99740" misc_feature complement(order(5031..5033,5499..5504,5514..5516, 5589..5591,5598..5600,5910..5915)) /locus_tag="ClothDRAFT_1896" /note="inhibitor-cofactor binding pocket; inhibition site" /db_xref="CDD:99740" misc_feature complement(order(5499..5501,5514..5516,5589..5591, 5598..5600,5814..5816,5910..5915)) /locus_tag="ClothDRAFT_1896" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99740" misc_feature complement(5499..5501) /locus_tag="ClothDRAFT_1896" /note="catalytic residue; other site" /db_xref="CDD:99740" gene 6558..7475 /locus_tag="ClothDRAFT_1897" CDS 6558..7475 /locus_tag="ClothDRAFT_1897" /inference="protein motif:PFAM:PF01370" /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mpo:Mpop_0774 NAD-dependent epimerase/dehydratase" /codon_start=1 /transl_table=11 /product="NAD-dependent epimerase/dehydratase" /protein_id="ZP_05430036.1" /db_xref="GI:256005066" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR002225" /translation="MTKTIITGASGFVGKSLVKELSAKGYEVLAIIRNKNKVSEFDDL SNVSVVVCDLRDISNLKNFLPKTDYSYFFHLAWEGTSGPDREDYHKQLQNVVYTCEAV KTAKELGCKRFIYAGSLMEYESIKYIPINGSIPVKNYIYRTAKLTAHYMAKSLAVDLG IDFVTGTISNAYGEGEISPRLINSTIRKLLKNEKTSFTSGEQLYDFIYITDVAKAFIA IAEKGRAYGNYYIGNRTQRKLKDYLIDIKNCIDKNIELGFGEIPFYGASLDYTEFDTN ALYEDTDFKCEVDFMEGIKKTIKWIEQNS" misc_feature 6564..>6914 /locus_tag="ClothDRAFT_1897" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" misc_feature 6570..7244 /locus_tag="ClothDRAFT_1897" /note="NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370" /db_xref="CDD:144821" gene 7522..9021 /locus_tag="ClothDRAFT_1898" CDS 7522..9021 /locus_tag="ClothDRAFT_1898" /inference="protein motif:PFAM:PF00535" /note="PFAM: glycosyl transferase family 2; KEGG: gbm:Gbem_3740 glycosyl transferase family 2" /codon_start=1 /transl_table=11 /product="glycosyl transferase family 2" /protein_id="ZP_05430037.1" /db_xref="GI:256005067" /db_xref="InterPro:IPR001173" /translation="MEDNIIIVDTSMIEAPKPGNTLYETRRNFADSYKVFNNQIAISI IAYNRLEKTKKCIEYLFKYTSHIDFELILCDNGSTDGTFEFFKSIDYPKKKIVRITKN LGAFFAANLIIDMAKCKYYVAMTNDAYVTENWLDNLLKCIESDDRIAYVSPMSSNMSN NQDPGLKFSSLEEMEIVASQFNKSDPRKWMERKRIVGVLACYRKDALDQIGKYDPGFF HEFSDDDFAFRVTRAGYKLVLCGDTFIHHDHAVFNMEDKDPETTKQSLRNGRKNFKDK YYGIDSWEDLLNFETPLINMASYENSNGENNVLGIDTKCGIPILEIKNKLRFNGADNI KLYAFTTKAKYYNDLLHTCEGNVNCDRIEFLNEYYVKDSFDYIILGEALNSYKEPFKL LENIIDLLQPSGQAVIKLKNTLEIRTLLSLYGHKQNFFEELLIHLSIDDVIAFLNQKN ISDVKLSGITYNVDNSINTFVNNTASSVGISPNSLGHLYINEYLIYIKK" misc_feature 7645..8268 /locus_tag="ClothDRAFT_1898" /note="Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186" /db_xref="CDD:133029" misc_feature order(7747..7749,7897..7902) /locus_tag="ClothDRAFT_1898" /note="Probable Catalytic site; other site" /db_xref="CDD:133029" misc_feature order(7900..7902,8188..8190,8194..8196) /locus_tag="ClothDRAFT_1898" /note="metal-binding site" /db_xref="CDD:133029" gene 9078..10091 /locus_tag="ClothDRAFT_1899" CDS 9078..10091 /locus_tag="ClothDRAFT_1899" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; KEGG: ppd:Ppro_3342 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05430038.1" /db_xref="GI:256005068" /db_xref="InterPro:IPR007197" /translation="MKAKKINGQAVNGKREMLASKLPLDTPYSITIFPIYACNFRCKY CLHSLEKDEREFISDTITMPWETYKKCIDDILKFPHKVKMLHLSGLGEPLLHKDIGKM VAYANQKGVAEGIDIVTNGSMLTKELTHELVDAGLTVLRISLQGINEEQYKREAGIDI DFDEFYNNIKYFYDNRGNTKLYIKVIDEILDDGQQEEFFNMFGDICDIIAIEHLCPFV DKINYTDTFNQNEFYVTMNGNQVPNTNICPQPFYSLQIYPDGKCIPCCTVEKPIVVGD CLKQSLVQIWNGDVMNSFRRLQLQSKKENNRVCAKCQQYKYGMFKEDILDEYASDLLK LYQ" misc_feature 9171..>9653 /locus_tag="ClothDRAFT_1899" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(9189..9191,9195..9197,9201..9203,9207..9215, 9339..9341,9348..9353,9429..9437,9504..9506,9621..9623) /locus_tag="ClothDRAFT_1899" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene 10246..11397 /locus_tag="ClothDRAFT_1900" CDS 10246..11397 /locus_tag="ClothDRAFT_1900" /inference="protein motif:TFAM:TIGR01444" /note="TIGRFAM: methyltransferase FkbM family; KEGG: sun:SUN_2141 methyltransferase FkbM" /codon_start=1 /transl_table=11 /product="methyltransferase FkbM family" /protein_id="ZP_05430039.1" /db_xref="GI:256005069" /db_xref="InterPro:IPR006342" /translation="MLSELVRLLDDFEKGNLDDEKGKFVELEGKSILLYGAGNIGKRL YQNLKNNKLNIVGFIDRNENLDKSAYEVEVYLPQSEKLNKYKENGIVILSALFSLNTV KEIKSSLHLLGFKNVFALHEINFSKINSVAFYEHLFDGSYNKLDLIGKDRQKIIDAFQ LLEGPKDQKLYIDYIKAHLTMDFTQFDDPEDITGQYLAKDIEYNKDYSTFIDCGGFDG DTIKNLVEHNVNIKNVIVFEPQNELCKKIKNYIDNIKIIESSVIFPCGVHSEFAKLRF STSSDAPSACKIDSGGNDMIQCVAIDDVLKNIRPTFIKMDIEGAELNALKGCKNTIVK YRPQLAICVYHSLSDIWNIPLLIHSYYSGYKFYLRSYNFMGLETVLYAF" misc_feature 10870..11268 /locus_tag="ClothDRAFT_1900" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene 11415..12668 /locus_tag="ClothDRAFT_1901" CDS 11415..12668 /locus_tag="ClothDRAFT_1901" /inference="protein motif:PFAM:PF00534" /note="PFAM: glycosyl transferase group 1; KEGG: ppd:Ppro_3344 glycosyl transferase, group 1" /codon_start=1 /transl_table=11 /product="glycosyl transferase group 1" /protein_id="ZP_05430040.1" /db_xref="GI:256005070" /db_xref="InterPro:IPR001296" /translation="MIKVVHITAHLGGGIGRILSSIAIYSQIEKEVEHVIVTLEKTEN SHFEQLLKEHSIKVFLQNQCCLKQILQEADIVEVDWWHHPLTSAFMHNYFNDIECRLL IWSHVSGCTYPYIKYELIKCADKFVFSTPFSFENEYWSNEEKEEVMKRVEIIVSSGID FDAPVKKKPHHGYNVGYIGFLSYSKTHPDFVRFLEAAADIPDICFKVVGDTAYGKELI KDVQNSKLVRNKVIFEGYALDVKEKFAEFDVFGYPLNPMHYGTAENALLEAMAAGVVP VVLNQCTEKYMVRHMETGIIVNSIEEYGAALRWLKDNADKRIHMGNNASEFVIKKLHI RETVNRLNACYSDMMSQNKRLHDIYSAIGTNPYEWFVSAYWGDVNCLEGNSFAETKGS AKHYLRYFPEDKILRKVVETNESRI" misc_feature <11859..12449 /locus_tag="ClothDRAFT_1901" /note="Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013" /db_xref="CDD:186885" gene 12652..13677 /locus_tag="ClothDRAFT_1902" CDS 12652..13677 /locus_tag="ClothDRAFT_1902" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: ppd:Ppro_3342 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05430041.1" /db_xref="GI:256005071" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /translation="MKAEFKPNYDTNRKKLADIIPLAAPFTVYIEQTRYCNFKCFYCI HATRDKEDGEFRKLGFSVKHMDFEMYKTIVSQLKKFTEPIKRIVFSGLGEPLMNPRLP EMVKLAVEAKIADRVEIITNGLLLTPETSRKLIDAGITNINISVQGVSKERYKETCGV EIDFDEYVKNLSYLYSIKGNTQIYIKAIDATLKSKEEEEKFFNIFGNICDKIYIEHLI VMQQQMGELKKIVDGTKNFYNEELDLNRKVCAQSFYFLQIGCDYDTFPCPVPGLPKSL SMGNIKDNTIKEIWNGEKRREHLRTMLSYQKDSIPECNNCTCFNAINNPLENLDPDAP RLLKLFE" misc_feature 12748..13302 /locus_tag="ClothDRAFT_1902" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(12757..12759,12763..12765,12769..12771,12775..12780, 12814..12816,12922..12924,12928..12933,13009..13017, 13084..13086,13201..13203,13297..13302) /locus_tag="ClothDRAFT_1902" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene 13711..14733 /locus_tag="ClothDRAFT_1903" CDS 13711..14733 /locus_tag="ClothDRAFT_1903" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; KEGG: ppd:Ppro_3342 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05430042.1" /db_xref="GI:256005072" /db_xref="InterPro:IPR007197" /translation="MASEIKPIYGTERIKLSKVIPLKTPFSIFVFPTTYCNFKCVYCA HSLGLDAMKKTYDFVPENMSMETYGKFIHQMKKFPDKLKMLCLMGQGEPLINKDIPVM VKMAKDAEIAERVEIISNGSLLDKTMSDRLIEAGLDTLRISLQGLNSKKYKDICGANI NFDDFMDNIRYFYAHKNNTNLFVKIMDVCLEEGEEEKFYRLFEDCSDRMYIEKMLPAY DGVEITKNMKVEYDRYGRKHEKRNVCPLPFYMLGIFPNGDVEPCDTIYKPIVLGNINN SELIDMWNGEKLREFWKLQLKGNRLQNDKCKVCCAPDDVSHPEDVLDDDVEEILKRLE TMESNI" misc_feature 13798..14418 /locus_tag="ClothDRAFT_1903" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(13816..13818,13822..13824,13828..13830,13834..13842, 13972..13974,13981..13986,14062..14070,14137..14139, 14260..14262,14347..14352) /locus_tag="ClothDRAFT_1903" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene 14730..15764 /locus_tag="ClothDRAFT_1904" CDS 14730..15764 /locus_tag="ClothDRAFT_1904" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; KEGG: ppd:Ppro_3342 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05430043.1" /db_xref="GI:256005073" /db_xref="InterPro:IPR007197" /translation="MRAVRIDGQTPGGKRNKLKDALPLDTPYMVQFFPIYACNFKCGY CIHSVPVSQRRYITDKTAMDFNLYKKCIDGLSKFPNKVKMIRFAGTGEPLLHKDIAKM VEYAVKMNVAEAVDIVTNGLLLEPDLSDKLIAAGLSKLRVSIQGVTSGKYEEISGKKV GISKIVDNLSYFYNAKQKSENTTQLYIKIIDCALEEGDEEKFLNMFGDICDIIAIEHL LPAVPQIEYKDKFNMDSDNLLTQNGNRILEAQVCPQPFYMMQINPEGNIVPCCAMETA KVIGNVNDNDLYSLWVGEEFNKFRRNLLSLNKQIYPVCKSCESYKYSMFEEDFLDDAR LKLLDLYVSR" misc_feature 14823..15389 /locus_tag="ClothDRAFT_1904" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(14841..14843,14847..14849,14853..14855,14859..14867, 14991..14993,15000..15005,15081..15089,15156..15158, 15282..15284,15378..15383) /locus_tag="ClothDRAFT_1904" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene 15803..16183 /locus_tag="ClothDRAFT_1905" CDS 15803..16183 /locus_tag="ClothDRAFT_1905" /inference="protein motif:PFAM:PF04488" /note="PFAM: glycosyltransferase sugar-binding region containing DXD motif; KEGG: acb:A1S_2896 hypothetical protein" /codon_start=1 /transl_table=11 /product="glycosyltransferase sugar-binding region containing DXD motif" /protein_id="ZP_05430044.1" /db_xref="GI:256005074" /db_xref="InterPro:IPR007577" /translation="MIPKVIHYFWFGRGKKNDVIERCMDSWKVHLPDYEIKEWNEDNF NVHINNFTLQAYQMKKWAFVSDYARLHILYHYGGIYLDTDLEITNSLDPFLDYEGFMG FFQILILAEELLEQQKEINSLKNC" misc_feature 15875..16102 /locus_tag="ClothDRAFT_1905" /note="Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488" /db_xref="CDD:146897" gene 16318..16785 /locus_tag="ClothDRAFT_1906" CDS 16318..16785 /locus_tag="ClothDRAFT_1906" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430045.1" /db_xref="GI:256005075" /translation="MTIFPKEYFTVRDVNVKNYAIHHYNASWLSHEEMNKHLKSYRKY YEFTVKWLDNLINNKIDLTPYKNKCIAIFGKGYIGELLVSYLQNNNVPIRQIIDTKFA NDTYKDIPIVSSDTISDEVNLIIITPIHSFESIYLSLKEKSCADIISIENLLS" gene complement(17022..17996) /locus_tag="ClothDRAFT_1907" CDS complement(17022..17996) /locus_tag="ClothDRAFT_1907" /inference="protein motif:PFAM:PF00404" /note="PFAM: cellulosome protein dockerin type I; KEGG: sde:Sde_0702 bis(5'-nucleosyl)-tetraphosphatase (symmetrical)" /codon_start=1 /transl_table=11 /product="cellulosome protein dockerin type I" /protein_id="ZP_05430046.1" /db_xref="GI:256005076" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MAYLDNELFVTALTDSQSLYWLPEGPNGMIAVIDTKTVELKEKI DIKIRPFNIFAGKNGYLYVTSREPQKAYFNSYSRSTKEFMDSELVNNECLSEYNPTLD RIYAIPIDIMPIDYKVLNVDNGKFVSSYSSTYYDSYPLAEKFKISPDGKYLFNSSGVV FTCNENVNEDMKFAFTLDKKFTDIAFNMEENRFYTAVGGNQIYVYNYEDFSGIDTLSS TGEILKLFYVDGKLCALSRSANGRPMFEVIQKVKIKYGDVNKDGRINSTDIMYLKGYL LRNSAFNLDEYGLMAADVDGNGSVSSLDLTYLKRYILRRISDFPANKK" gene complement(18111..18287) /locus_tag="ClothDRAFT_1908" CDS complement(18111..18287) /locus_tag="ClothDRAFT_1908" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430047.1" /db_xref="GI:256005077" /translation="MPKSNERLELFVLICFVMSSFLTNLTVFPVKAAEESLIPKNEFE DFKFPIGTKSSDAI" sig_peptide complement(18189..18287) /locus_tag="ClothDRAFT_1908" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.939) with cleavage site probability 0.925 at residue 33" gene complement(18392..19903) /locus_tag="ClothDRAFT_1909" CDS complement(18392..19903) /locus_tag="ClothDRAFT_1909" /inference="protein motif:PFAM:PF06964" /note="PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: rlt:Rleg2_5890 alpha-N-arabinofuranosidase" /codon_start=1 /transl_table=11 /product="alpha-L-arabinofuranosidase domain protein" /protein_id="ZP_05430048.1" /db_xref="GI:256005078" /db_xref="InterPro:IPR010720" /translation="MKKARMTVDKDYKIAEIDKRIYGSFVEHLGRAVYDGLYQPGNSK SDEDGFRKDVIELVKELNVPIIRYPGGNFVSNYFWEDGVGPVEDRPRRLDLAWKSIEP NQVGINEFAKWCKKVNAEIMMAVNLGTRGISDACNLLEYCNHPGGSKYSDMRIKHGVK EPHNIKVWCLGNEMDGPWQVGHKTMDEYGRIAEETARAMKMIDPSIELVACGSSSKDM PTFPQWEATVLDYAYDYVDYISLHQYYGNKENDTADFLAKSDDLDDFIRSVIATCDYI KAKKRSKKDIYLSFDEWNVWYHSNNEDANIMQNEPWRIAPPLLEDIYTFEDALLVGLM LITLMKHADRIKIACLAQLINVIAPIVTERNGGAAWRQTIFYPFMHASKYGRGIVLQP VINSPLHDTSKHEDVTDIESVAIYNEEKEEVTIFAVNRNIHEDIVLVSDVRGMKDYRL LEHIVLEHQDLKIRNSVNGEEVYPKNSDKSSFDDGILTSMLRRASWNVIRIGK" misc_feature complement(18395..19903) /locus_tag="ClothDRAFT_1909" /note="Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; cl01412" /db_xref="CDD:154388" gene complement(20102..20428) /locus_tag="ClothDRAFT_1910" CDS complement(20102..20428) /locus_tag="ClothDRAFT_1910" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430049.1" /db_xref="GI:256005079" /translation="MPGSKVTDDGYVRGYYFKIPKDASDRRLTQININGGDYHVFGIR LGDSVEQAAEKLKQRGYKRTKSMEDIYREGIHRTRFQKELVIIDLQTEMNSQIIKGIS VLTDYP" gene complement(20459..20641) /locus_tag="ClothDRAFT_1911" CDS complement(20459..20641) /locus_tag="ClothDRAFT_1911" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430050.1" /db_xref="GI:256005080" /translation="MKKAITIIILTCLFLLLGTLVFVKYEENASIKLVEKTIQEAQEI NANSFMGMEYLEFAGL" sig_peptide complement(20570..20641) /locus_tag="ClothDRAFT_1911" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.892) with cleavage site probability 0.834 at residue 24" gene 20912..21007 /locus_tag="ClothDRAFT_1912" CDS 20912..21007 /locus_tag="ClothDRAFT_1912" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430051.1" /db_xref="GI:256005081" /translation="MLQIALCDDNTNDLSTMIHLLDEYKSSKQRI" gene 21066..21311 /locus_tag="ClothDRAFT_1913" CDS 21066..21311 /locus_tag="ClothDRAFT_1913" /inference="protein motif:COG:COG3947" /note="KEGG: reh:H16_A2233 response regulator containing a LytTR DNA-binding domain" /codon_start=1 /transl_table=11 /product="response regulator receiver and SARP domain protein" /protein_id="ZP_05430052.1" /db_xref="GI:256005082" /db_xref="InterPro:IPR001789" /translation="MPGFTGIDLANEIRGSDKTAPILFFTSSAEFALESYSVRAADYV LKPVSKEKLFLTFDELLEQIEAQKKENTIIVKSCDGI" misc_feature <21066..21248 /locus_tag="ClothDRAFT_1913" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(21066..21071,21075..21083) /locus_tag="ClothDRAFT_1913" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature order(21081..21083,21141..21143,21192..21194,21201..21206) /locus_tag="ClothDRAFT_1913" /note="active site" /db_xref="CDD:29071" misc_feature 21201..21209 /locus_tag="ClothDRAFT_1913" /note="dimerization interface; other site" /db_xref="CDD:29071" gene 21613..22101 /locus_tag="ClothDRAFT_1914" CDS 21613..22101 /locus_tag="ClothDRAFT_1914" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430053.1" /db_xref="GI:256005083" /translation="MIEILFGTATAVSFAGMERTRKNYIAVGCLTTVLFFLQVICLNA WDIDVTFKLYPLLSHLPITVFIVAYLKRPWLISLTSVLASFLCCQPPRWIGTALGEVF DSVSINHVSYIAAAFLTYCFLRKYAVTSVRHLIERSVSSCLLFGAMPAFYYLFEYVGF PV" gene 22082..22699 /locus_tag="ClothDRAFT_1915" CDS 22082..22699 /locus_tag="ClothDRAFT_1915" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: vfi:VF_0524 sensory histidine kinase in two-compoent regulatory system with PhoP" /codon_start=1 /transl_table=11 /product="signal transduction histidine kinase regulating citrate/malate metabolism" /protein_id="ZP_05430054.1" /db_xref="GI:256005084" /translation="MLDSQFKQAQKEFESLRQMQKTTASYRHDMRHHFALLQSMASKG NMEDIKEYLQTVQSDLDAITPVRFCENETVNLILSSFAAKAKQSEVRLTIDAKLPDSY PFSDTELCSLLSNTLENAIHASKQITDISKRIIHLRMFSRNNKLCIDIRNSYQKEPVF HHGLPVSKEQGHGFGTKSMAHIVEKYGGVFQFSVKDGWFIFQATT" misc_feature <22091..22684 /locus_tag="ClothDRAFT_1915" /note="Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290" /db_xref="CDD:33099" misc_feature 22406..22645 /locus_tag="ClothDRAFT_1915" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075" /db_xref="CDD:185789" gene 23021..23602 /locus_tag="ClothDRAFT_1916" CDS 23021..23602 /locus_tag="ClothDRAFT_1916" /inference="protein motif:TFAM:TIGR02937" /note="TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: sfu:Sfum_0272 transcriptional regulator, fis family" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma-24 subunit, ECF subfamily" /protein_id="ZP_05430055.1" /db_xref="GI:256005085" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR014284" /translation="MIGVLTMNKERDNILIESTLKGNINSFEELMTLYQGKLFNFLLK MTSSREDAEEITQEVFIKVYNNLYKYNNRWSFSTWIYRIAINTLRSEYRKAKNVKSVD YYTNVSELPANFSDYPELAYEMKERQKEIIKLIDELKEDQKTALLLRYMQDFSFKEIG DILGISPEAAKMKIQRAKQSICKKYEELEKDGG" misc_feature 23054..23596 /locus_tag="ClothDRAFT_1916" /note="DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595" /db_xref="CDD:31783" misc_feature 23108..23308 /locus_tag="ClothDRAFT_1916" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature 23408..23563 /locus_tag="ClothDRAFT_1916" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cd06171" /db_xref="CDD:100119" misc_feature order(23435..23437,23465..23467,23483..23488,23516..23518, 23522..23527,23531..23539,23543..23548,23552..23554) /locus_tag="ClothDRAFT_1916" /note="DNA binding residues" /db_xref="CDD:100119" gene 23605..25002 /locus_tag="ClothDRAFT_1917" CDS 23605..25002 /locus_tag="ClothDRAFT_1917" /inference="protein motif:COG:COG5401" /note="KEGG: prw:PsycPRwf_1162 hypothetical protein" /codon_start=1 /transl_table=11 /product="Spore germination protein-like protein" /protein_id="ZP_05430056.1" /db_xref="GI:256005086" /db_xref="InterPro:IPR001199" /translation="MKCNFNFEDIIKYSENHLSEEEKKRIKEHLDVCEKCRKRYGVLK FTEAYAKDSSMTSESITKNVMETIDVNRYSKSKKFLFGRNFYRALPVIKPVLASAAVF VVVMVGITSFGSLRGLINNSGDVKPNPTNPIANSQNTNPAALPESTAPAVQNPVEKKV ITLYYSNSNADKVVAEKREVEISKDTQIERLVFEELQKGPKNEGLVATIPKGTRLLSV STENGICTLNLSKEFVDNHPGGTAGETMTLFSIVNTMTELPGIEKVQFLIEGQKQDAY IHVAFSEPFKRNNSIIQKSPSEIKAEVEAKSQEAIKAIKEKDMEKLAQMVHPEKGVLF SPYSHIELEKHKVFTKDQLKNLMESEEVYIWGEYDGSGDPIKLTFAQYFDKFVYDHDF ANAEKVAYNEIQQSGNTIVNISDVYPEGKFMDYYFPGFTPEYDGMDWASLRLVFEEYD GQWYLVCIAHGQWTI" misc_feature 24085..24426 /locus_tag="ClothDRAFT_1917" /note="Sporulation and spore germination; Region: Germane; pfam10646" /db_xref="CDD:151159" gene complement(25076..25321) /locus_tag="ClothDRAFT_1918" CDS complement(25076..25321) /locus_tag="ClothDRAFT_1918" /inference="protein motif:PFAM:PF01206" /note="PFAM: SirA family protein; KEGG: afw:Anae109_2274 SirA-like protein" /codon_start=1 /transl_table=11 /product="SirA family protein" /protein_id="ZP_05430057.1" /db_xref="GI:256005087" /db_xref="InterPro:IPR001455" /translation="MSDIKADAFVDITDVVCPMTFVKAKIAIEELEEGQILEIKMNEG EPILNVPRSFKEEGHRVLDVVNNEDGTFTVFVEKGKV" misc_feature complement(25088..25294) /locus_tag="ClothDRAFT_1918" /note="SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-...; Region: SirA_YedF_YeeD; cl00436" /db_xref="CDD:185995" gene complement(25359..26231) /locus_tag="ClothDRAFT_1919" CDS complement(25359..26231) /locus_tag="ClothDRAFT_1919" /inference="protein motif:PFAM:PF01077" /note="PFAM: nitrite and sulphite reductase 4Fe-4S region; 4Fe-4S ferredoxin iron-sulfur binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: gsu:GSU1351 iron-sulfur cluster-binding protein" /codon_start=1 /transl_table=11 /product="nitrite and sulphite reductase 4Fe-4S region" /protein_id="ZP_05430058.1" /db_xref="GI:256005088" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR005117" /db_xref="InterPro:IPR006066" /db_xref="InterPro:IPR006067" /db_xref="InterPro:IPR017900" /translation="MANVDYKELKKGGFMKQVDKDRFSLRLRIVGGQIKAEQLAKVNE IAQKYGAGYIHLTSRQSIEIPYIKLQDIDAVKEELAKAGLQPGACGPRVRTITACQGA VICPSGLINTTELAREFDERYYARELPHKFKLGITGCRNNCLKAEENDLGVKGGMMPS WVKDKCIYCGLCQAVCPAKVIEVKKQEKELTFNEKDCIYCGKCVKVCPTSAWEGRGGF IVYFGGLFGNRIAVGKQLLPIIFSKEDLHKVIEATLAFFEEHGKPGERFGNTLDRVGW DLLKNRLEEVLKAG" misc_feature complement(25368..26201) /locus_tag="ClothDRAFT_1919" /note="Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion]; Region: DsrA; COG2221" /db_xref="CDD:32403" misc_feature complement(25986..26189) /locus_tag="ClothDRAFT_1919" /note="Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460" /db_xref="CDD:146216" misc_feature complement(25599..25664) /locus_tag="ClothDRAFT_1919" /note="4Fe-4S binding domain; Region: Fer4; pfam00037" /db_xref="CDD:143826" gene complement(26232..26651) /locus_tag="ClothDRAFT_1920" CDS complement(26232..26651) /locus_tag="ClothDRAFT_1920" /inference="protein motif:PFAM:PF01398" /note="PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: gur:Gura_3942 Mov34/MPN/PAD-1 family protein" /codon_start=1 /transl_table=11 /product="Mov34/MPN/PAD-1 family protein" /protein_id="ZP_05430059.1" /db_xref="GI:256005089" /db_xref="InterPro:IPR000555" /translation="MIVMTKQQYQEILEHSRNALPNEACGLLGGRIENGVKYVEKVYL LRNIDESPEHFSMNPKEQFAAVKDMRNNGWELLGNFHSHPATPSRPSEEDIRLAFDPK ASYLILSLKDDTPVLKSFNISSGQATQEELSIVGEEA" misc_feature complement(26256..26636) /locus_tag="ClothDRAFT_1920" /note="Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding); Region: MPN_like; cd08070" /db_xref="CDD:163701" misc_feature complement(order(26370..26372,26379..26381,26403..26405, 26409..26411,26583..26585)) /locus_tag="ClothDRAFT_1920" /note="MPN+ (JAMM) motif; other site" /db_xref="CDD:163701" misc_feature complement(order(26370..26372,26403..26405,26409..26411)) /locus_tag="ClothDRAFT_1920" /note="Zinc-binding site; other site" /db_xref="CDD:163701" gene complement(26675..27487) /locus_tag="ClothDRAFT_1921" CDS complement(26675..27487) /locus_tag="ClothDRAFT_1921" /inference="protein motif:PFAM:PF00899" /note="PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: gme:Gmet_1568 UBA/ThiF-type NAD/FAD binding fold:MoeZ/MoeB" /codon_start=1 /transl_table=11 /product="UBA/THIF-type NAD/FAD binding protein" /protein_id="ZP_05430060.1" /db_xref="GI:256005090" /db_xref="InterPro:IPR000594" /db_xref="InterPro:IPR007901" /translation="MNFTNEQMERYSRHIILKDVGVKGQKKLLESKVLIIGTGGLGAP AAMFLAAAGVGTIGLVDFDAVELSNLQRQIIHLTKDVGKPKVISGKETINEMNPDVNV VTYQEWVSSANIKDIIKDRDYDFIIDGTDNFPAKFLINDACVLTGKPFSHAGIIRFQG QTMTYVPGKGPCYRCIFENPPPPDKVPTCKQAGVLGVMGGVIGTIQATEAIKYLLGIG ELLTGYILTYDAKAMEFRKVKLPWNKRCQVCGENPTIKELIDYEQAVCDLKS" misc_feature complement(26750..27481) /locus_tag="ClothDRAFT_1921" /note="molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690" /db_xref="CDD:180204" misc_feature complement(26768..27460) /locus_tag="ClothDRAFT_1921" /note="ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of...; Region: ThiF_MoeB_HesA_family; cd00757" /db_xref="CDD:30111" misc_feature complement(order(27083..27085,27101..27103,27233..27235, 27272..27274,27299..27301,27305..27307,27365..27367, 27371..27373,27377..27379)) /locus_tag="ClothDRAFT_1921" /note="ATP binding site; other site" /db_xref="CDD:30111" misc_feature complement(order(26771..26776,26780..26782,26801..26803, 26813..26815,27005..27007,27011..27013,27023..27028, 27080..27082,27092..27100,27365..27367)) /locus_tag="ClothDRAFT_1921" /note="substrate interface; other site" /db_xref="CDD:30111" gene complement(27484..27693) /locus_tag="ClothDRAFT_1922" CDS complement(27484..27693) /locus_tag="ClothDRAFT_1922" /inference="protein motif:TFAM:TIGR01683" /note="TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gbm:Gbem_1981 thiamine biosynthesis protein ThiS" /codon_start=1 /transl_table=11 /product="thiamine biosynthesis protein ThiS" /protein_id="ZP_05430061.1" /db_xref="GI:256005091" /db_xref="InterPro:IPR003749" /db_xref="InterPro:IPR010035" /translation="MTIKVNGKDVTLEKEVTVKELLEIQKVEMPDYVTVQINDKILDR KDFETLTVKEGDVVEFLYFMGGGAI" misc_feature complement(27493..27690) /locus_tag="ClothDRAFT_1922" /note="ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565" /db_xref="CDD:176353" misc_feature complement(order(27511..27519,27571..27573)) /locus_tag="ClothDRAFT_1922" /note="thiS-thiF/thiG interaction site; other site" /db_xref="CDD:176353" gene complement(27712..29511) /locus_tag="ClothDRAFT_1923" CDS complement(27712..29511) /locus_tag="ClothDRAFT_1923" /inference="protein motif:TFAM:TIGR02034" /note="TIGRFAM: sulfate adenylyltransferase, large subunit; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: gur:Gura_3828 sulfate adenylyltransferase, large subunit" /codon_start=1 /transl_table=11 /product="sulfate adenylyltransferase, large subunit" /protein_id="ZP_05430062.1" /db_xref="GI:256005092" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR004161" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR011779" /translation="MEAREQMNIVIVGHVDHGKSTVIGRLLADTGSLPEGKLESVKEF CRKNARPFEYAFLLDALKDEQAQGITIDTARCFFKTNKRDYIIIDAPGHVEFLKNMVT GASRAEAALLVIDAKEGIKENSKRHGHIVSMLGIKQVVVLVNKMDLVGFDREVYEAIV SEFGEFLQKVNIRPINYIPISAFNGDNIAQRSRNTLWYDGPTVLEQLDGFVNKKENRQ LPFRMPVQDIYKFTEEGDDRRIVAGTIISGSISVGDEVVFLPSNKKSVIKSIEGFNVK PRNTAYADEAIGVTLTTQIYIKPGELMVKANEKHPSVSSRFRANIFWVGKAPLIKNKN YKLKIGTMKIGVKLIEISHIIDAAELNIDTFKDQVERHDVAECIFETAKPIAYDVISE IEQTGRFVIVDNYEISGGGIILEAVPDTDSSLLTHIREREFLWEKSLISAKQRENAYG HKAKFIVITSGSEGKEKDIQDIGRQLEERLFNMKYKAYYLGVSSILHGLASDVANSYE DRDEHIRQIGELARIFTDSGQIFITSIFNLDDYEAKKLKLLNQPNEIIVVNIGQTPFN NFVPDANIEDTEGAVEAVCELLKRQEIILEYYI" misc_feature complement(28258..29511) /locus_tag="ClothDRAFT_1923" /note="GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895" /db_xref="CDD:32720" misc_feature complement(28870..29490) /locus_tag="ClothDRAFT_1923" /note="CysN_ATPS subfamily. CysN, together with protein CysD, form the ATP sulfurylase (ATPS) complex in some bacteria and lower eukaryotes. ATPS catalyzes the production of ATP sulfurylase (APS) and pyrophosphate (PPi) from ATP and sulfate. CysD, which...; Region: CysN_ATPS; cd04166" /db_xref="CDD:133366" misc_feature complement(order(29197..29199,29206..29208,29254..29256, 29260..29262,29281..29283,29287..29289,29293..29298, 29488..29490)) /locus_tag="ClothDRAFT_1923" /note="CysD dimerization site; other site" /db_xref="CDD:133366" misc_feature complement(29452..29475) /locus_tag="ClothDRAFT_1923" /note="G1 box; other site" /db_xref="CDD:133366" misc_feature complement(order(29026..29028,29038..29040,29158..29163, 29230..29235,29287..29292,29428..29433,29440..29442, 29449..29454,29464..29466,29470..29472)) /locus_tag="ClothDRAFT_1923" /note="putative GEF interaction site; other site" /db_xref="CDD:133366" misc_feature complement(order(28963..28971,29068..29073,29077..29082, 29326..29328,29449..29460,29464..29466)) /locus_tag="ClothDRAFT_1923" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133366" misc_feature complement(29290..29322) /locus_tag="ClothDRAFT_1923" /note="Switch I region; other site" /db_xref="CDD:133366" misc_feature complement(29302..29304) /locus_tag="ClothDRAFT_1923" /note="G2 box; other site" /db_xref="CDD:133366" misc_feature complement(29236..29247) /locus_tag="ClothDRAFT_1923" /note="G3 box; other site" /db_xref="CDD:133366" misc_feature complement(29185..29241) /locus_tag="ClothDRAFT_1923" /note="Switch II region; other site" /db_xref="CDD:133366" misc_feature complement(29071..29082) /locus_tag="ClothDRAFT_1923" /note="G4 box; other site" /db_xref="CDD:133366" misc_feature complement(28963..28971) /locus_tag="ClothDRAFT_1923" /note="G5 box; other site" /db_xref="CDD:133366" misc_feature complement(28597..28851) /locus_tag="ClothDRAFT_1923" /note="CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of...; Region: CysN_NodQ_II; cd03695" /db_xref="CDD:58086" misc_feature complement(28270..28575) /locus_tag="ClothDRAFT_1923" /note="TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of...; Region: CysN_NoDQ_III; cd04095" /db_xref="CDD:58077" misc_feature complement(<27910..28098) /locus_tag="ClothDRAFT_1923" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" gene complement(29513..30394) /locus_tag="ClothDRAFT_1924" CDS complement(29513..30394) /locus_tag="ClothDRAFT_1924" /inference="protein motif:PFAM:PF01507" /note="PFAM: phosphoadenosine phosphosulfate reductase; KEGG: wsu:WS1009 sulfate adenylyltransferase subunit 2" /codon_start=1 /transl_table=11 /product="phosphoadenosine phosphosulfate reductase" /protein_id="ZP_05430063.1" /db_xref="GI:256005093" /db_xref="InterPro:IPR002500" /translation="MDHLDKLEAQSIYILREAYREFKNICMLWSIGKDSTVLLWLARK AFFGHVPIPLVHIDTHYKIPEMIEYRDELARKWKLTMIYGENSEALAQKKTFPDGNVD RLTCCQLLKTEALKHTLSGEWNRYILDHKTGKYVLDTKRERFTGVIVGVRADEEGSRS KERYFSPRDKESDWAVEDQPPEFWNQFKTDFAPGTHIRIHPLLDWTELNIWEYIEREN IPVTPLYFDRGDGKRYRSLGCYPCTFPVESTAKNVREIIEELKSGKFANIAERAGRAQ DQDDGGGLETLRRGGYM" misc_feature complement(29519..30385) /locus_tag="ClothDRAFT_1924" /note="sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039" /db_xref="CDD:131094" misc_feature complement(29681..30325) /locus_tag="ClothDRAFT_1924" /note="This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713" /db_xref="CDD:30168" misc_feature complement(order(29801..29803,29813..29815,29918..29920, 30062..30064)) /locus_tag="ClothDRAFT_1924" /note="Active Sites; active site" /db_xref="CDD:30168" gene complement(30682..31401) /locus_tag="ClothDRAFT_1925" CDS complement(30682..31401) /locus_tag="ClothDRAFT_1925" /EC_number="1.8.4.8" /inference="protein motif:TFAM:TIGR02055" /note="KEGG: abu:Abu_2173 phosphoadenosine phosphosulfate reductase; TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase" /codon_start=1 /transl_table=11 /product="adenylylsulfate reductase, thioredoxin dependent" /protein_id="ZP_05430064.1" /db_xref="GI:256005094" /db_xref="InterPro:IPR002500" /db_xref="InterPro:IPR004511" /db_xref="InterPro:IPR011798" /translation="MVQLDLEKLNKEYSDKSPEDIVRFVVENIGIEKVALASSLSIED QVLTDILLKINPKARVFFLDTGRHFQQTYDLMEETMHRYGFHYEVYAPESKELEQAVS KYGPNFFYESVELRKKCCEIRKVNPLKRVLSTVDAWICGLRREQSLTRQELNIFEWDG LHSIYKINPIVFWSEDRVWEYIKKYNIPYNSLYSKGFRSIGCQPCTRAVRPGEDVRSG RWWWEDPDKKECGLHARVGQV" misc_feature complement(30799..31305) /locus_tag="ClothDRAFT_1925" /note="This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713" /db_xref="CDD:30168" misc_feature complement(order(30904..30906,30916..30918,30952..30954, 31030..31032)) /locus_tag="ClothDRAFT_1925" /note="Active Sites; active site" /db_xref="CDD:30168" gene complement(31469..32533) /locus_tag="ClothDRAFT_1926" CDS complement(31469..32533) /locus_tag="ClothDRAFT_1926" /inference="protein motif:TFAM:TIGR00968" /note="KEGG: gur:Gura_3891 sulfate ABC transporter, ATPase subunit; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="sulfate ABC transporter, ATPase subunit" /protein_id="ZP_05430065.1" /db_xref="GI:256005095" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005666" /db_xref="InterPro:IPR017871" /translation="MSIEIRNVSKTFDSFKALSNINLHINTGELVALLGPSGSGKTTL LRIIAGLETADEGSIIFDGEDNTKKSAQDRKVGFVFQHYALFKHMTVFENIAFGLRVM PSKIRPNKEAIKNKVYELLKLVKMEELANRYPSQLSGGQRQRIALARALAVEPKVLLL DEPFGALDAKVRKDLRRWLRKLHDEYPITSVFVTHDQEEALDVADRVVILNQGKIEQI GTPEEVYDNPANPFVYNFLGNVNLFHGRIHNGKVELGLPGADSDGGQGKDIVSYTRPH DIEIKLEPEGKEFIGSRITFIRAVGPIVKIELVRLDNGQYIEAEISKETYRKLGLKER QTVYVRPKDFKVFIPEDYVI" misc_feature complement(31484..32533) /locus_tag="ClothDRAFT_1926" /note="ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118" /db_xref="CDD:31315" misc_feature complement(31817..32533) /locus_tag="ClothDRAFT_1926" /note="Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-...; Region: ABC_CysA_sulfate_importer; cd03296" /db_xref="CDD:73055" misc_feature complement(32408..32431) /locus_tag="ClothDRAFT_1926" /note="Walker A/P-loop; other site" /db_xref="CDD:73055" misc_feature complement(order(31949..31951,32048..32053,32291..32293, 32405..32413,32417..32422)) /locus_tag="ClothDRAFT_1926" /note="ATP binding site; other site" /db_xref="CDD:73055" misc_feature complement(32291..32302) /locus_tag="ClothDRAFT_1926" /note="Q-loop/lid; other site" /db_xref="CDD:73055" misc_feature complement(32096..32125) /locus_tag="ClothDRAFT_1926" /note="ABC transporter signature motif; other site" /db_xref="CDD:73055" misc_feature complement(32048..32065) /locus_tag="ClothDRAFT_1926" /note="Walker B; other site" /db_xref="CDD:73055" misc_feature complement(32030..32041) /locus_tag="ClothDRAFT_1926" /note="D-loop; other site" /db_xref="CDD:73055" misc_feature complement(31943..31963) /locus_tag="ClothDRAFT_1926" /note="H-loop/switch region; other site" /db_xref="CDD:73055" gene complement(32576..33460) /locus_tag="ClothDRAFT_1927" CDS complement(32576..33460) /locus_tag="ClothDRAFT_1927" /inference="protein motif:TFAM:TIGR02140" /note="TIGRFAM: sulfate ABC transporter, inner membrane subunit CysW; sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rme:Rmet_1377 sulfate ABC transporter, permease protein CysW" /codon_start=1 /transl_table=11 /product="sulfate ABC transporter, inner membrane subunit CysW" /protein_id="ZP_05430066.1" /db_xref="GI:256005096" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR005667" /db_xref="InterPro:IPR011866" /translation="MAGIVPVRIKTANKVEYAKKRAVKDSKIVQVVLTTIAILFFIIM LIVPLVSVFVKAFEQGANLYFASITDPIALKAIKLTLITIAITVPINTIFGLAAAWAI AKFKFKGKNILITIIDLPFSISPVVAGLIFVLLFSTSHGLLGPLLNALGIKIIFAPPG IVIATLFVTLPFVARELIPLMEAQGTAEEEAALTLGASGWKTFWYITLPNIKWALLYG VMLTTARAAGEFGAVSVVSGHIRGLTNTVPLHVEILYNEYKFSAAFAVASLLTLIALI NLIVKNVAHWKIQQQSKI" misc_feature complement(32636..33130) /locus_tag="ClothDRAFT_1927" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature complement(order(32636..32641,32648..32653,32660..32665, 32669..32674,32681..32686,32714..32719,32756..32761, 32768..32779,32798..32800,32807..32812,32852..32854, 32903..32905,32912..32917,32927..32929,32933..32938, 32945..32947,32951..32953,32960..32965,33062..33064, 33068..33073,33080..33109,33113..33124)) /locus_tag="ClothDRAFT_1927" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature complement(order(32762..32779,33062..33106)) /locus_tag="ClothDRAFT_1927" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature complement(order(32684..32686,32714..32716,32723..32725, 32759..32761,32978..32980,33062..33064)) /locus_tag="ClothDRAFT_1927" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature complement(order(32831..32833,32843..32848,32864..32902)) /locus_tag="ClothDRAFT_1927" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" gene complement(33547..34395) /locus_tag="ClothDRAFT_1928" CDS complement(33547..34395) /locus_tag="ClothDRAFT_1928" /inference="protein motif:TFAM:TIGR02139" /note="TIGRFAM: sulfate ABC transporter, inner membrane subunit CysT; sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mfa:Mfla_0611 sulfate ABC transporter, permease protein CysT" /codon_start=1 /transl_table=11 /product="sulfate ABC transporter, inner membrane subunit CysT" /protein_id="ZP_05430067.1" /db_xref="GI:256005097" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR005667" /db_xref="InterPro:IPR011865" /translation="MNLGIKPFKLKQKSVIPGFGITMGFTLTYLTLLVLIPVSMVFLN SAQIGLDKFWEIVSSERVLASLKISFGTSFLAAAINVVFGLLLAWVLERYDFWGKKLV DGLIDLPFALPTAVAGISLTTLYSQNGWIGRLFAPFGIKISYTPLGIVVALVFIGFPF VVRTVQPVLESFDVEVEEAAACLGATRFQTFCRVILPELFPALITGFALAFSRALGEY GSVVFISGNMPMKTEITPLLIRTKLEQYDYAGGTAVAAVMLVISFILLLMINAFQWWA GRHRSR" misc_feature complement(33607..34200) /locus_tag="ClothDRAFT_1928" /note="Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits...; Region: TM_PBP2; cd06261" /db_xref="CDD:119394" misc_feature complement(order(33607..33612,33619..33624,33631..33636, 33640..33645,33652..33657,33685..33690,33727..33732, 33739..33750,33769..33771,33778..33783,33823..33825, 33874..33876,33883..33888,33898..33900,33904..33909, 33916..33918,33922..33924,33931..33936,34030..34032, 34036..34041,34048..34077,34081..34092,34120..34122, 34135..34140,34147..34152)) /locus_tag="ClothDRAFT_1928" /note="dimer interface; other site" /db_xref="CDD:119394" misc_feature complement(order(33733..33750,34030..34074)) /locus_tag="ClothDRAFT_1928" /note="conserved gate region; other site" /db_xref="CDD:119394" misc_feature complement(order(33655..33657,33685..33687,33694..33696, 33730..33732,33949..33951,34030..34032)) /locus_tag="ClothDRAFT_1928" /note="putative PBP binding loops; other site" /db_xref="CDD:119394" misc_feature complement(order(33802..33804,33814..33819,33835..33873)) /locus_tag="ClothDRAFT_1928" /note="ABC-ATPase subunit interface; other site" /db_xref="CDD:119394" gene complement(34420..35490) /locus_tag="ClothDRAFT_1929" CDS complement(34420..35490) /locus_tag="ClothDRAFT_1929" /inference="protein motif:TFAM:TIGR00971" /note="TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: gur:Gura_3894 sulfate ABC transporter, periplasmic sulfate-binding protein" /codon_start=1 /transl_table=11 /product="sulfate ABC transporter, periplasmic sulfate-binding protein" /protein_id="ZP_05430068.1" /db_xref="GI:256005098" /db_xref="InterPro:IPR000957" /db_xref="InterPro:IPR005669" /db_xref="InterPro:IPR006059" /translation="MEKNKGRKNILKSSLAVLLIIAGLVSFAGCAKEAGNNQSDSGQT EPVTILNVSYDPTRELYQDYNEAFRKYWKEKTGKDIVIQQSHGGSGSQARAVIDGLEA DVVTLALAYDIDSINKNKEILSKDWQKRLPYNSTPYTSTIVFLVRKGNPKNIKDWDDL ARPGVEVITPNPKTSGGARWNYLAAWGYALKKYGNDPEKAKEFVKAIYANVPVLDSGA RGSTTTFVERGLGDVLIAWENEAFLSLNELGKDKFEIVVPSVSILAEPPVAVVDSVVD KKGTREVAEAYLEYLYSDEGQEIAAKNYYRPRKEEIKQKYASQFAEVELFTIDEVFGG WDKAQKEHFDDGGIFDQIYEKK" sig_peptide complement(35395..35490) /locus_tag="ClothDRAFT_1929" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.926 at residue 32" misc_feature complement(34426..35451) /locus_tag="ClothDRAFT_1929" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398" /db_xref="CDD:187020" gene complement(35799..37082) /locus_tag="ClothDRAFT_1930" CDS complement(35799..37082) /locus_tag="ClothDRAFT_1930" /inference="protein motif:TFAM:TIGR00713" /note="TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gbm:Gbem_3927 glutamate-1-semialdehyde-2,1-aminomutase" /codon_start=1 /transl_table=11 /product="glutamate-1-semialdehyde-2,1-aminomutase" /protein_id="ZP_05430069.1" /db_xref="GI:256005099" /db_xref="InterPro:IPR004639" /db_xref="InterPro:IPR005814" /translation="MTLSKSKLLFERAKKVIPGGVNSPVRAFGAVGGYPPFIKKAKGA RIYDADGNEYIDYVGSWGPMILGHSHPRVLEAVSKTMVDGLSFGAATELEVQMAELIT ELVPSVEMVRMVNSGTEAVMSAIRVARGYTKREKIIKFAGCYHGHADSMLVKVGSGAM TNGIPNSGGVTAGAAKDTLIARYNDIDSVKLLFEQNKGNIAAVIVEPVAANMGVVPPK DNFLEELRKLCDKEEALLIFDEVITGFRLAIGGAQQYFGVNADLVTYGKIIGGGMPVG AYGGRREIMECVAPVGDVYQAGTLSGNPIAMSAGIATLRELYENPGIFENINRLGQRL SEGLGKITKYTVKAVGSLVCVFMTEEEVNDYDSAVKSDTGLFGRYFNHLLNNGIYIAP SQFEAMFVSNAHTDKDIDETLEKVSLFFARKSPPA" misc_feature complement(35817..37076) /locus_tag="ClothDRAFT_1930" /note="glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062" /db_xref="CDD:178834" misc_feature complement(35835..37058) /locus_tag="ClothDRAFT_1930" /note="Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase...; Region: OAT_like; cd00610" /db_xref="CDD:99735" misc_feature complement(order(36282..36284,36357..36362,36366..36368, 36465..36467,36642..36644,36648..36653,36729..36737)) /locus_tag="ClothDRAFT_1930" /note="inhibitor-cofactor binding pocket; inhibition site" /db_xref="CDD:99735" misc_feature complement(order(36282..36284,36357..36359,36366..36368, 36465..36467,36648..36653,36729..36734)) /locus_tag="ClothDRAFT_1930" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99735" misc_feature complement(36282..36284) /locus_tag="ClothDRAFT_1930" /note="catalytic residue; other site" /db_xref="CDD:99735" gene complement(37082..38062) /locus_tag="ClothDRAFT_1931" CDS complement(37082..38062) /locus_tag="ClothDRAFT_1931" /EC_number="4.2.1.24" /inference="protein motif:PRIAM:4.2.1.24" /note="PFAM: delta-aminolevulinic acid dehydratase; KEGG: dal:Dalk_3857 porphobilinogen synthase" /codon_start=1 /transl_table=11 /product="Porphobilinogen synthase" /protein_id="ZP_05430070.1" /db_xref="GI:256005100" /db_xref="InterPro:IPR000005" /db_xref="InterPro:IPR001731" /translation="MLIRPRRLRLNQHIRDMAREVRLSSKSLILPLFLMEGKNVKLPV NSLEGHFYYSPDTVFEAVDDALKCGVNKFLLFGLPSEKDEIGSQSFNENGVIQKAVRA IKERYRDEVLVITDVCMCEYTSHGHCGILNHGYVDNDKTLEYLAKIALSHAAAGADMV APSDMMDGRVAAIRQELDKHNFINTLIMSYAVKYSSSFYGPFRDAAKSAPSFGDRKSY QMDYHNKKEAVKEALTDINEGADILMVKPALAYLDVISEVSKHSSLPTAAYSVSGEYA MIKAAAKMNLIDEYPTMCETAVSIFRAGADILISYYAKEIAEAINRGDIG" misc_feature complement(37109..38047) /locus_tag="ClothDRAFT_1931" /note="Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384" /db_xref="CDD:88598" misc_feature complement(order(37157..37159,37166..37168,37178..37180, 37232..37234,37304..37318,37370..37375,37382..37384, 37400..37402,37409..37411,37469..37477,37562..37567, 37646..37651,37919..37921,37928..37930,38000..38002, 38033..38038,38045..38047)) /locus_tag="ClothDRAFT_1931" /note="dimer interface; other site" /db_xref="CDD:88598" misc_feature complement(order(37130..37132,37247..37249,37256..37258, 37325..37327,37406..37408,37418..37420,37439..37441, 37454..37459,37466..37468,37484..37486,37574..37576, 37679..37681,37703..37705,37709..37711,37715..37717)) /locus_tag="ClothDRAFT_1931" /note="active site" /db_xref="CDD:88598" misc_feature complement(order(37325..37327,37484..37486)) /locus_tag="ClothDRAFT_1931" /note="Schiff base residues; other site" /db_xref="CDD:88598" gene complement(38331..39812) /locus_tag="ClothDRAFT_1932" CDS complement(38331..39812) /locus_tag="ClothDRAFT_1932" /inference="protein motif:TFAM:TIGR01469" /note="TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dds:Ddes_2207 uroporphyrin-III C-methyltransferase" /codon_start=1 /transl_table=11 /product="uroporphyrin-III C-methyltransferase" /protein_id="ZP_05430071.1" /db_xref="GI:256005101" /db_xref="InterPro:IPR000878" /db_xref="InterPro:IPR003043" /db_xref="InterPro:IPR003754" /db_xref="InterPro:IPR006366" /translation="MADGKGKVYLVGAGPGDEELLTVKAADVIKKADVIVYDRLISDG ILSKIPDNAEKIYVGKNAGNHPVPQHEINKILLAKALEAKIVVRLKGGDPFVFGRGGE ELEFLHQNGIPFEVVPGITSAIAAAAYAGIPVTHRDFCSSLHIITGHVKDGGNPDIDY ESLVKLKGTLIFMMSVASFPQIAQGLIEAGMESDMDAAVIENGTMPNQRKFVSKLCDI PKVIAENQVKSPAIIIVGKVCSLSEKLDWFSKLPLYGCNVLVTGPKKTSERLAGKLRG LGAHVVEYPCIETEPLDFDIDIREHSWIIFTSSLGVTIFFKKLYENKLDSRYLYNKKI AAVGSQTAEELLKHGICADFVPGKFDGRHLAEELLQSGKISPEDKVVIFRAKDGTQAI VDIFENNNIHYTDISVYETKCIENERIDISGFNYITFTSESCVKGFAHSFKNTIDYSK INAICIGEQTAKATRAYGMNTIISDVATVSSMVEKIIEMHCAK" misc_feature complement(39087..39794) /locus_tag="ClothDRAFT_1932" /note="Tetrapyrrole (Corrin/Porphyrin) Methylases; Region: TP_methylase; cl00304" /db_xref="CDD:185890" misc_feature complement(38355..39041) /locus_tag="ClothDRAFT_1932" /note="Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations...; Region: HemD; cd06578" /db_xref="CDD:119440" misc_feature complement(order(38511..38525,38580..38582,38586..38588, 38658..38660,38793..38795,38883..38891,39027..39029)) /locus_tag="ClothDRAFT_1932" /note="active site" /db_xref="CDD:119440" misc_feature complement(38361..39011) /locus_tag="ClothDRAFT_1932" /note="Uroporphyrinogen-III synthase HemD; Region: HEM4; pfam02602" /db_xref="CDD:145641" gene complement(39812..40690) /locus_tag="ClothDRAFT_1933" CDS complement(39812..40690) /locus_tag="ClothDRAFT_1933" /EC_number="2.5.1.61" /inference="protein motif:TFAM:TIGR00212" /note="KEGG: vpa:VP2988 porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase" /codon_start=1 /transl_table=11 /product="porphobilinogen deaminase" /protein_id="ZP_05430072.1" /db_xref="GI:256005102" /db_xref="InterPro:IPR000860" /translation="MKIRVGSRESKLAVRQAQIVIDSIKKYNPDIEIELVTMKTTGDK ILDKTIDKIGGKGLFVKELDRALLDGKVDITVHSFKDMPMDIDDRLPIVAVSKREDPR DVLVLPKGKNEIDFNGPIGCSSSRRKIQIEKIYPGCTVEPIRGNVLTRLEKLDKGEYS AIALAYAGLKRLGLEERIWRVFSTDEIVPAACQGIIAVQARKDFDASILANFHDKDSW DVSVAERSFIKALNGGCSSPSAAYGVIQGEKIVLTGFYVDKNGKIYKMTKTGDRNQGE ALGYSLAMEMLKGADA" misc_feature complement(39827..40690) /locus_tag="ClothDRAFT_1933" /note="porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072" /db_xref="CDD:178840" misc_feature complement(39827..40684) /locus_tag="ClothDRAFT_1933" /note="Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494" /db_xref="CDD:29604" misc_feature complement(order(39896..39898,39899..39901,39908..39910, 39917..39919,39932..39934,39968..39970,39974..39976, 39986..39988,40007..40009,40016..40021,40031..40033, 40040..40042,40061..40063,40109..40132,40178..40183, 40190..40192,40253..40255,40292..40294,40304..40309, 40313..40315,40382..40399,40403..40408,40433..40435, 40439..40456,40646..40648,40661..40663)) /locus_tag="ClothDRAFT_1933" /note="domain interfaces; other site" /db_xref="CDD:29604" misc_feature complement(order(39986..39988,40109..40114,40121..40123, 40178..40180,40187..40189,40196..40204,40241..40243, 40262..40264,40310..40315,40319..40327,40448..40453, 40457..40459,40643..40645,40655..40657)) /locus_tag="ClothDRAFT_1933" /note="active site" /db_xref="CDD:29604" gene complement(40665..41138) /locus_tag="ClothDRAFT_1934" CDS complement(40665..41138) /locus_tag="ClothDRAFT_1934" /EC_number="1.3.1.76" /inference="protein motif:TFAM:TIGR01470" /note="TIGRFAM: siroheme synthase; KEGG: geo:Geob_1302 siroheme synthase" /codon_start=1 /transl_table=11 /product="siroheme synthase" /protein_id="ZP_05430073.1" /db_xref="GI:256005103" /db_xref="InterPro:IPR006367" /translation="MKEHFPLFISSRGKKVLVVGGGKIATRRILTLTNFEFEITVVAP NITNEIQQLADDGLVTHIQREFRNEDLDGKFLVVAATDKREINKYIGEKAKELGAYVS VADVKEECNFYFPAVIVKDEIVVGVTGDGKSHKKVKEISNKIRKVLKHENQSGQP" misc_feature complement(40695..41138) /locus_tag="ClothDRAFT_1934" /note="precorrin-2 dehydrogenase; Validated; Region: PRK06719" /db_xref="CDD:180668" gene complement(41135..42130) /locus_tag="ClothDRAFT_1935" CDS complement(41135..42130) /locus_tag="ClothDRAFT_1935" /EC_number="1.2.1.70" /inference="protein motif:PRIAM:1.2.1.70" /note="PFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase-like; Shikimate/quinate 5-dehydrogenase; KEGG: esa:ESA_01496 glutamyl-tRNA reductase" /codon_start=1 /transl_table=11 /product="Glutamyl-tRNA reductase" /protein_id="ZP_05430074.1" /db_xref="GI:256005104" /db_xref="InterPro:IPR006151" /db_xref="InterPro:IPR015895" /translation="MNVIMAGIDYTLAPIDIREKFSFTKSTLQAVYNDLLKNENIFGA VIVSTCNRTELYLSCEEGLYINPFELLCDAANFDYEEYSNMHVLRTGVDVIRHLCELA CGVKSQIWGEDQIITQVRNAIELAREMNASDSTLEVMFRIAVTSAKKVKTTLKLSSTE RSIAYSALKIIKSKENISKALVIGNGEIGRLMASILIENGYDTTITLRRYRHGDNIIP LGAKTIEYVARYEKLKDCDVVISATLSPHYTLEIDKIDRIKYPRLFIDLAVPRDIDPK IKSLDNVELYDLDSIYAGEVDKNRTEQMIQVKKIIDKYIFDYYRWYEYRKRLVLT" misc_feature complement(41231..42121) /locus_tag="ClothDRAFT_1935" /note="NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213" /db_xref="CDD:133452" misc_feature complement(order(41747..41749,41759..41761,41768..41770, 41780..41782,41789..41791,41984..41986,42074..42076)) /locus_tag="ClothDRAFT_1935" /note="tRNA; other site" /db_xref="CDD:133452" misc_feature complement(order(41777..41779,41789..41791,41795..41797, 41810..41812,41975..41977,41981..41986)) /locus_tag="ClothDRAFT_1935" /note="putative tRNA binding site; other site" /db_xref="CDD:133452" misc_feature complement(order(41564..41566,41573..41575,41579..41581)) /locus_tag="ClothDRAFT_1935" /note="putative NADP binding site; other site" /db_xref="CDD:133452" gene complement(42360..42803) /locus_tag="ClothDRAFT_1936" CDS complement(42360..42803) /locus_tag="ClothDRAFT_1936" /inference="protein motif:TFAM:TIGR00738" /note="TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: sat:SYN_03008 rrf2 family protein" /codon_start=1 /transl_table=11 /product="transcriptional regulator, BadM/Rrf2 family" /protein_id="ZP_05430075.1" /db_xref="GI:256005105" /db_xref="InterPro:IPR000944" /translation="MKMSTKGRYGLRAMLDIAVNSKGDIVSVKSIAERQNISESYLEQ VFSILRKAAIVKSIKGAQGGYVLADDPSNITVGKILRTLEGNLNVVDIDDRDSEVSKE EKCINEFVWNKINKSIDKVVDNITLGDLLREYQKLEDNSSVMYYI" misc_feature complement(42408..42803) /locus_tag="ClothDRAFT_1936" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" misc_feature complement(42408..42803) /locus_tag="ClothDRAFT_1936" /note="rrf2 family protein (putative transcriptional regulator); Region: rrf2_super; TIGR00738" /db_xref="CDD:129821" gene complement(43073..43453) /locus_tag="ClothDRAFT_1937" CDS complement(43073..43453) /locus_tag="ClothDRAFT_1937" /inference="similar to AA sequence:KEGG:Mlg_1165" /note="KEGG: aeh:Mlg_1165 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430076.1" /db_xref="GI:256005106" /db_xref="InterPro:IPR006121" /translation="MELTTPALLFPAISLLMLAYTNRFVVLAQLIRELYAKYKENPDE VTKGQLYNLKRRIVIIKNMQIFGALSFFFCVTCMFLIFFKVMFLADIVFGISLLLLLI SLGLLVYELQISINALNIQLKDFE" misc_feature complement(43088..43447) /locus_tag="ClothDRAFT_1937" /note="Protein of unknown function (DUF2721); Region: DUF2721; pfam11026" /db_xref="CDD:151473" gene complement(43647..45269) /locus_tag="ClothDRAFT_1938" CDS complement(43647..45269) /locus_tag="ClothDRAFT_1938" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430077.1" /db_xref="GI:256005107" /db_xref="InterPro:IPR006311" /translation="MRAMVVDMNDKYAVVVNKEGQYIKIKRKAEHRLGYQVELPDRVI GFERRTLLKVVSVAAALLIVSSISFAVYSYNLPYSYVNVDINPSLEIILNMYNRIIDV KALNSEGEMLIEDSYKNSRLDEGVEKIIDSAVAQGFLKNDEENTIMLTVAGKNSRKVL EIKEEVESTANKVLNDDNVVSEVIVENIVLERREEARELGISPGKLLLIEKLKEVDPK ATTEEYKDKPVNEIVKTIRDIKKVPNENNRKDDDKKVNNEPNKPLPDRKADVETSAGV KENTAGPDAGIKPVNKTDNAKPNVGTDINNKENKTVSNAKIDSGIDKGNKDSKPNSNT KINNDVKKDNKDNKTNSDAKTFNDVSKDNKNDKADGNAKINNNINRDNKITPINPDNK FSSGGSKDDKDNKHVDSKDKMNNEDNKNINNGSCPQYNPYWNPYWNPYWNPYWGNPKE KEDMTKQNDEWFKKMQEEQKKQYDEWLKKMQEEQKKQHDEWVKKMEEMKNTEKMKNPY QENKIEKPKEAEKENKPDRPPEPGKEILKKRY" gene complement(45269..45976) /locus_tag="ClothDRAFT_1939" CDS complement(45269..45976) /locus_tag="ClothDRAFT_1939" /inference="protein motif:TFAM:TIGR02895" /note="TIGRFAM: RNA polymerase sigma-I factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma 28 subunit, SigI" /protein_id="ZP_05430078.1" /db_xref="GI:256005108" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR014244" /db_xref="InterPro:IPR014284" /translation="MYSVTINQRVEAIKNNEEEINLFVEEYKPFIAACTQKVVGRYVA YGQDDELSIALMAFVEAIRSYDVSKGNFLSFSQNVIKRRIIDYYRKEKKHSVVVNING HLEDEEEETDLGIAMSIDKYSEEEISEYRRLELEQLKKELKEWDISFFDLVNISPKHK RTKKIYSKIIKFVLSRPDIMEKIKQKKYLPVAEIEQSLKIPRKTIERARKYIITVVII FTGDYEFIRDYVNWEVE" misc_feature complement(45272..45964) /locus_tag="ClothDRAFT_1939" /note="putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311" /db_xref="CDD:181376" misc_feature complement(45698..45910) /locus_tag="ClothDRAFT_1939" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" gene complement(46172..46429) /locus_tag="ClothDRAFT_1940" CDS complement(46172..46429) /locus_tag="ClothDRAFT_1940" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430079.1" /db_xref="GI:256005109" /translation="MILVGRLIKGTHAIKESVFNKEAEDTDFRDLLEEGLISLCRELD IPVPLWLNKNTSEFARYRKTFFDRDQFIEDVKFDRFELRME" gene complement(46469..48049) /locus_tag="ClothDRAFT_1941" CDS complement(46469..48049) /locus_tag="ClothDRAFT_1941" /EC_number="2.3.1.182" /inference="protein motif:TFAM:TIGR00977" /note="KEGG: ppd:Ppro_2313 alpha-isopropylmalate/homocitrate synthase family transferase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain" /codon_start=1 /transl_table=11 /product="2-isopropylmalate synthase/homocitrate synthase family protein" /protein_id="ZP_05430080.1" /db_xref="GI:256005110" /db_xref="InterPro:IPR000891" /db_xref="InterPro:IPR002034" /db_xref="InterPro:IPR005675" /db_xref="InterPro:IPR013709" /translation="MKKILIYDSTLRDGAQAQGISFSVEDKLKIVERLDRLGISYIEA GNPGSNPKDLEFFDRIGRVKLRHAKIIAFGSTRRVNVSVQEDANVKSLLKADTPAVAI FGKSWDFHVTDILKTTLDENLRMIFDTISFFKNKNKEVVFDAEHFFDGYKANPDYAMK TLKTAVEAGADCICLCDTNGGTFPNEIKDITARVVSEFNVNVGIHCHNDTGMAVANSI MAVLAGAVQVQGTMNGFGERSGNANLCTIIPNLQLKAGYDCIPQENMADLTATARSIS EIANVIHDERAPYVGKYAFAHKAGMHADAVTKNSIAYEHINPEVVGNERLFLMSEVAG RSAVLHLIKNIDSTITKDSPETKLILDKLKELEFEGYQYEGAESSFEIVIRKILGKYR PSFELGEFKVVVNEPSISGANSSAMIKINVDGQYEITADEGQGPVNALDKALRKALEK FYPQIAEMKLTDYKVRVLDSNSATAAKVRVLIESTDGKEVWTTIGVSTDIIEASWKAL VDSIEYKLIKDKEAKQKS" misc_feature complement(46481..48049) /locus_tag="ClothDRAFT_1941" /note="putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional; Region: PRK12344" /db_xref="CDD:183457" misc_feature complement(47219..48034) /locus_tag="ClothDRAFT_1941" /note="Desulfobacterium autotrophicum LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA3; cd07941" /db_xref="CDD:163679" misc_feature complement(order(47429..47431,47435..47437,47522..47524, 47615..47617,47825..47827,47831..47833,47921..47923, 48002..48004,48011..48016)) /locus_tag="ClothDRAFT_1941" /note="active site" /db_xref="CDD:163679" misc_feature complement(order(47921..47923,48011..48016)) /locus_tag="ClothDRAFT_1941" /note="catalytic residues; other site" /db_xref="CDD:163679" misc_feature complement(order(47429..47431,47435..47437,47522..47524, 48011..48013)) /locus_tag="ClothDRAFT_1941" /note="metal-binding site" /db_xref="CDD:163679" misc_feature complement(46502..46867) /locus_tag="ClothDRAFT_1941" /note="LeuA allosteric (dimerization) domain; Region: LeuA_dimer; pfam08502" /db_xref="CDD:149524" gene complement(48132..49127) /locus_tag="ClothDRAFT_1942" CDS complement(48132..49127) /locus_tag="ClothDRAFT_1942" /EC_number="1.1.1.86" /inference="protein motif:TFAM:TIGR00465" /note="KEGG: dvl:Dvul_1690 ketol-acid reductoisomerase; TIGRFAM: ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase catalytic domain protein; CoA-binding domain protein; acetohydroxy acid isomeroreductase" /codon_start=1 /transl_table=11 /product="ketol-acid reductoisomerase" /protein_id="ZP_05430081.1" /db_xref="GI:256005111" /db_xref="InterPro:IPR000506" /db_xref="InterPro:IPR003781" /db_xref="InterPro:IPR013023" /db_xref="InterPro:IPR013116" /translation="MAKIYYDSDCNLGLLKGKTVAIIGYGSQGHAHAQNLRDSGIDVV VGLPEGSKSRQKAVEDGLRVENTDVAAKMADVVMMLVPDQLQQDIYENSIKPNLEEGN VLAFAHGFAIHFKTIVPPPEVDVIMIAPKGPGHTVRSQYVEGKGVPSLIAVYQDASGK AKDYALAYAAGIGAGRAGILETTFKEETETDLFGEQAVLCGGVTELMKAGFETLVEAG YQPEIAYFECIHEMKLIVDLINQGGFSYMRYSISDTAEYGDYITGKKIITEETRKAMK AVLKDIQDGVFASKWITENKAGGRAQFLAMRRNEAEHQLEKVGAELRKMMSWLKK" misc_feature complement(48135..49127) /locus_tag="ClothDRAFT_1942" /note="ketol-acid reductoisomerase; Provisional; Region: PRK05479" /db_xref="CDD:180113" misc_feature complement(48639..49088) /locus_tag="ClothDRAFT_1942" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" misc_feature complement(48138..48578) /locus_tag="ClothDRAFT_1942" /note="Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450" /db_xref="CDD:110451" gene complement(49135..49647) /locus_tag="ClothDRAFT_1943" CDS complement(49135..49647) /locus_tag="ClothDRAFT_1943" /inference="protein motif:TFAM:TIGR00119" /note="TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sfu:Sfum_3022 acetolactate synthase, small subunit" /codon_start=1 /transl_table=11 /product="acetolactate synthase, small subunit" /protein_id="ZP_05430082.1" /db_xref="GI:256005112" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR004789" /translation="MAKHTLSVLVENHAGVLSRIAGLFSRRGFNIDSLAVGVTENPEI SRMTIVVDGDDYIVEQVTKQLNKLVDVIKIKELDESDSVSRELALIKVGANASTRSEI VQIAEIFRAKIVDVSKTTLTIEISGSVDKVAALEDMLKQFGIKEIVRTGTIAIERGNK VIKNKNSDEE" misc_feature complement(49162..49641) /locus_tag="ClothDRAFT_1943" /note="acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895" /db_xref="CDD:183365" misc_feature complement(49426..49638) /locus_tag="ClothDRAFT_1943" /note="N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878" /db_xref="CDD:153150" misc_feature complement(order(49513..49515,49540..49542,49555..49560, 49597..49599,49612..49614,49618..49620)) /locus_tag="ClothDRAFT_1943" /note="putative valine binding site; other site" /db_xref="CDD:153150" misc_feature complement(order(49510..49512,49540..49554,49564..49566, 49573..49575,49594..49596,49603..49608)) /locus_tag="ClothDRAFT_1943" /note="dimer interface; other site" /db_xref="CDD:153150" misc_feature complement(49174..49398) /locus_tag="ClothDRAFT_1943" /note="Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369" /db_xref="CDD:150959" gene complement(49679..51307) /locus_tag="ClothDRAFT_1944" CDS complement(49679..51307) /locus_tag="ClothDRAFT_1944" /inference="protein motif:TFAM:TIGR00118" /note="TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: gur:Gura_3720 acetolactate synthase, large subunit, biosynthetic type" /codon_start=1 /transl_table=11 /product="acetolactate synthase, large subunit, biosynthetic type" /protein_id="ZP_05430083.1" /db_xref="GI:256005113" /db_xref="InterPro:IPR000399" /db_xref="InterPro:IPR011766" /db_xref="InterPro:IPR012000" /db_xref="InterPro:IPR012001" /db_xref="InterPro:IPR012846" /translation="MKLSGAQAIVKALELEGVEVVFGYPGAAICPFYDALMESKIRHI LTRHEQGAAHAASGYARTTGRVGVCVATSGPGATNLITGIADAYMDSIPLVAITGQVN SELIGRDVFQEADITGATDPFCKHNYLVKNAKDLPRVLKEAFYIASTGRPGPVLIDVP IDVQTKEINFEYPESVDIKGYKPNLKGHSLQIKKIAQAIEKAKKPVICAGGGVINSNA SEELLTLSRKCGIPVVTTLMGIGSVPYDYELNLGMLGTHGVYIANYAVNNADLLIIIG ARVADRAISNPQQVAKRKQIVHIDIDPAEIGKNIDVSIPVVGDVKQVLKELIDISQKG DTEEWIKTTQKEREKHAEKPEPRPGIGFVNPKYLLSVLTGLLGDDDIITTEVGQNQIW AANYFGVKKPRTFITSGGLGTMGYGLPAAVGAKIGCPDRKVVCVGGDGSFQMNMQELG TIKQNRLGVKVILFNNSRLGMVRELQKTKYCGRYFQVFLDDNPDFIKLFDAYGFKGRR IDDDSQVEDALKEMLSDDKPYLLECKIDPEESTL" misc_feature complement(49691..51304) /locus_tag="ClothDRAFT_1944" /note="acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK06048" /db_xref="CDD:180368" misc_feature complement(50825..51289) /locus_tag="ClothDRAFT_1944" /note="Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035" /db_xref="CDD:132918" misc_feature complement(order(51038..51043,51050..51052,51062..51064, 51083..51085,51119..51127,51131..51136,51143..51148, 51155..51157,51164..51184,51206..51208,51218..51220, 51230..51235,51248..51250)) /locus_tag="ClothDRAFT_1944" /note="PYR/PP interface; other site" /db_xref="CDD:132918" misc_feature complement(order(50942..50944,50951..50953,51053..51055, 51062..51067,51071..51076,51083..51085,51158..51160, 51164..51175,51179..51181,51206..51208,51218..51220, 51227..51235)) /locus_tag="ClothDRAFT_1944" /note="dimer interface; other site" /db_xref="CDD:132918" misc_feature complement(order(51071..51073,51083..51085,51161..51163, 51233..51235)) /locus_tag="ClothDRAFT_1944" /note="TPP binding site; other site" /db_xref="CDD:132918" misc_feature complement(50327..50695) /locus_tag="ClothDRAFT_1944" /note="Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205" /db_xref="CDD:143962" misc_feature complement(49691..50221) /locus_tag="ClothDRAFT_1944" /note="Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015" /db_xref="CDD:48178" misc_feature complement(order(49910..49912,49976..49978,49985..49993, 50066..50068,50072..50074,50141..50152)) /locus_tag="ClothDRAFT_1944" /note="TPP-binding site; other site" /db_xref="CDD:48178" misc_feature complement(order(49805..49807,49814..49816,49826..49831, 49946..49948,49967..49972,49976..49981,50066..50068, 50072..50074,50081..50083)) /locus_tag="ClothDRAFT_1944" /note="dimer interface; other site" /db_xref="CDD:48178" gene complement(51689..52153) /locus_tag="ClothDRAFT_1945" CDS complement(51689..52153) /locus_tag="ClothDRAFT_1945" /inference="protein motif:PFAM:PF00383" /note="PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sun:SUN_1183 cytidine/deoxycytidylate deaminase family protein" /codon_start=1 /transl_table=11 /product="CMP/dCMP deaminase zinc-binding" /protein_id="ZP_05430084.1" /db_xref="GI:256005114" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR016192" /translation="MDDFMKEAVKEAVSGMRQNHGGPFGAVIVKDNEIIARAHNEVIK NNDPTDHAEMIAIRKAAKKLSRFDLGDCELYSSCEPCPMCFAAIHWAKIKKVYYGCTR EDAAKIGFDDNYIYEVIKGETDEKRVSLVQTDRDACLEAFKEWERKQDKVQY" misc_feature complement(51815..52141) /locus_tag="ClothDRAFT_1945" /note="Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285" /db_xref="CDD:29828" misc_feature complement(order(51902..51904,51911..51913,51995..52003, 52034..52036,52082..52084)) /locus_tag="ClothDRAFT_1945" /note="nucleoside/Zn binding site; other site" /db_xref="CDD:29828" misc_feature complement(order(51881..51886,51893..51898,51905..51910, 51980..51982,51992..51994,52007..52009)) /locus_tag="ClothDRAFT_1945" /note="dimer interface; other site" /db_xref="CDD:29828" misc_feature complement(order(51902..51904,51911..51916,51995..52003)) /locus_tag="ClothDRAFT_1945" /note="catalytic motif; other site" /db_xref="CDD:29828" gene complement(52303..52596) /locus_tag="ClothDRAFT_1946" CDS complement(52303..52596) /locus_tag="ClothDRAFT_1946" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430085.1" /db_xref="GI:256005115" /translation="MDTQRKIQDKNDFKKMIKTYLKQGRNKLLNEFTGTREAMGRIAT EKIKDFIKVMDVGLDEAEREYLRELIVSGMYQSFCYGYSIGKIEGKSENRILI" gene complement(52702..53880) /locus_tag="ClothDRAFT_1947" CDS complement(52702..53880) /locus_tag="ClothDRAFT_1947" /inference="protein motif:PFAM:PF00089" /note="PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: pca:Pcar_2948 serine endoprotease" /codon_start=1 /transl_table=11 /product="peptidase S1 and S6 chymotrypsin/Hap" /protein_id="ZP_05430086.1" /db_xref="GI:256005116" /db_xref="InterPro:IPR001254" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR001940" /db_xref="InterPro:IPR008256" /translation="MFDNGRRKNGFFTMFLTSLLTSLGVGILLIFAVTGFVTGNRSTA PQTPQGGSGIEMPSPQQISAEQSNNTGGQNTIQSVAENASKAVVGISVLKVDSSSIFN PNAVERWGVGSGVIVTPNGYILTNHHVAGGKSKRIVVSLVDGKNLDGVTVWSDSVLDL AVVKIEAEGLPTIPLGDATKLKVGEPAIAIGNPLGLQFQRTVTSGIISALNRTIEVDT EQGTNYMEGLIQTDASINPGNSGGPLLNLKGEVVGINTVKVASAEGIGFAVPINVAIP IINKFATTGEFIEPYLGVFAYDKDIIPYLDGNVKVQNGVYVANVDENGPAYKSGIRVG CIMTQIDGEEISTMMQLRCVIYSKNPGDVVTIRHISNGKPQTVQVRLAAKEKDGLVTR " sig_peptide complement(53749..53880) /locus_tag="ClothDRAFT_1947" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.967) with cleavage site probability 0.368 at residue 44" misc_feature complement(52717..53724) /locus_tag="ClothDRAFT_1947" /note="Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265" /db_xref="CDD:30614" misc_feature complement(53047..53541) /locus_tag="ClothDRAFT_1947" /note="Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic...; Region: Tryp_SPc; cl00149" /db_xref="CDD:153545" misc_feature complement(52744..53013) /locus_tag="ClothDRAFT_1947" /note="PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind C-...; Region: PDZ_serine_protease; cd00987" /db_xref="CDD:29044" misc_feature complement(order(52825..52830,52837..52842,52993..52995, 52999..53010)) /locus_tag="ClothDRAFT_1947" /note="protein binding site; other site" /db_xref="CDD:29044" gene complement(53968..54168) /locus_tag="ClothDRAFT_1948" CDS complement(53968..54168) /locus_tag="ClothDRAFT_1948" /inference="protein motif:PFAM:PF06107" /note="PFAM: protein of unknown function DUF951" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF951" /protein_id="ZP_05430087.1" /db_xref="GI:256005117" /db_xref="InterPro:IPR009296" /translation="MEHRYRIGEIVELKKQHPCGSKQWEITRVGADFKIKCLGCQHQV MLPRPKFEKSVKKIIRSLEEDL" misc_feature complement(53992..54159) /locus_tag="ClothDRAFT_1948" /note="Bacterial protein of unknown function (DUF951); Region: DUF951; cl01864" /db_xref="CDD:154632" gene complement(54374..55222) /locus_tag="ClothDRAFT_1949" CDS complement(54374..55222) /locus_tag="ClothDRAFT_1949" /inference="protein motif:PFAM:PF00924" /note="PFAM: MscS Mechanosensitive ion channel; KEGG: mxa:MXAN_0606 small conductance mechanosensitive ion channel (MscS) family protein" /codon_start=1 /transl_table=11 /product="MscS Mechanosensitive ion channel" /protein_id="ZP_05430088.1" /db_xref="GI:256005118" /db_xref="InterPro:IPR006685" /translation="MILDIVDIIEWITNIPGNLKIILGGLYNPLVLIVKIIAVLVISV LLSKFGSKMIRKAMEKQKSFKHRLDDKRIDTMSTLLVSVFRYTVYILSGVAILTLLTN ALNLQSVLAAAGIGGLAVGFASQSLIKDVISGAFIVFENQYSVGDMVTLEDRTGVVEE IELRVTKIRDSKGDLHIIPNGEIKKVTNHSRGNKTVVVDIPLPYRVDVNKVFEAADKV CRSVSEEFDTIVENPRVLGITELARGGFTLRITAKTLPGAHWEVERRIRKAIKEEFDR ENIELS" misc_feature complement(54380..54859) /locus_tag="ClothDRAFT_1949" /note="Mechanosensitive ion channel; Region: MS_channel; pfam00924" /db_xref="CDD:144501" gene complement(55653..56510) /locus_tag="ClothDRAFT_1950" CDS complement(55653..56510) /locus_tag="ClothDRAFT_1950" /inference="protein motif:PFAM:PF04018" /note="PFAM: protein of unknown function DUF368; KEGG: abo:ABO_1170 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF368" /protein_id="ZP_05430089.1" /db_xref="GI:256005119" /db_xref="InterPro:IPR007163" /translation="MKSGLKDDLFTIVKGYIIGSSMSVPGVSGGTMAILLGIYDRLIS SISNFLKDIKGNVLFLVKFCIGAGLGICSLSFLIKWLLEKFPVPVSMFFLGAVIGGIP ALYKKTKESSLRISSAFYFLLGLLVVISIGFIPEESINIGSGSGVVHYLMILVAGIVI ALALVLPGISTSHMLLVLGMYESMLTAITEFDVFYIGTLGIATLIGVFLITKPIEWTL NTFPHQTYCAIIGFVLGSTAEIFQEKILPAIPENAGVPWWIGCGLMSIATFILGFMAI KSLSRFQED" misc_feature complement(55683..56420) /locus_tag="ClothDRAFT_1950" /note="Domain of unknown function (DUF368); Region: DUF368; cl00893" /db_xref="CDD:154069" gene complement(56760..58718) /locus_tag="ClothDRAFT_1951" CDS complement(56760..58718) /locus_tag="ClothDRAFT_1951" /inference="protein motif:PFAM:PF01131" /note="PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein; KEGG: neu:NE1966 DNA topoisomerase III" /codon_start=1 /transl_table=11 /product="DNA topoisomerase type IA central domain protein" /protein_id="ZP_05430090.1" /db_xref="GI:256005120" /db_xref="InterPro:IPR000380" /db_xref="InterPro:IPR003601" /db_xref="InterPro:IPR003602" /db_xref="InterPro:IPR006154" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR013497" /translation="MGKKLYITEKPSVAASFAEVLGMKITKQDRSKGYAESEHSVVTW CFGHLITMAYPDAYDPKYREWKVEDLPIIPKVYKYIVIDDEGIKKQFETIKTLMNRED IDLIFACTDSGREGEYIFRLVYEQSGSNKKAKRVWISSQTEEAIREGILNAKDIEEYD SLARAAYSRAKEDWLFGMNFSRIYTCLYGRKLSNFLKESKTSVIAIGRVMTCVLGLVV DREQEIRNFMPKKHYGITATFLSSVSNLLYKGKWVPQNKKDDKEADDEEKYISREEAE QVIERLKGHPGKIKKVEVKTKKEQPPLLFNLAELQSEANKKFKLPVDKTLEIAQWLYE KKLITYPRTDSRVISTDVLEEVPKVLNGIYKNPEYRDYVLKIKEMGDLKVTKSTKRYV DNSKVTDHYAIIPTYVNAETVRMDENTKNVYNLIVKRFLAIFFPPAVYNTVRVETVVN NEIFVSNAKTLKEAGWKEVYEVSAPKQDEELTEAPIHLLVKNEAVEAKDFELEEKETK PPSRYTDGSLIITMEKAGKFIEDEELREQIKTCGIGTSATRAGIIKKLSDIGYIKINP KTQVVTPTLKGEAIVELVRRTARELLSPSLTASWEKGLAMIENKETTAEIFEEKLCVY INKTINKVKRGESNIDFEKIIDARAKVK" misc_feature complement(56787..58712) /locus_tag="ClothDRAFT_1951" /note="DNA topoisomerase III; Provisional; Region: PRK07726" /db_xref="CDD:181093" misc_feature complement(58272..58712) /locus_tag="ClothDRAFT_1951" /note="TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by:...; Region: TOPRIM_TopoIA_TopoIII; cd03362" /db_xref="CDD:173782" misc_feature complement(order(58374..58376,58380..58382,58386..58388, 58680..58682,58689..58694)) /locus_tag="ClothDRAFT_1951" /note="active site" /db_xref="CDD:173782" misc_feature complement(order(58344..58349,58353..58358,58377..58379, 58383..58385,58671..58673)) /locus_tag="ClothDRAFT_1951" /note="putative interdomain interaction site; other site" /db_xref="CDD:173782" misc_feature complement(order(58380..58382,58386..58388)) /locus_tag="ClothDRAFT_1951" /note="putative metal-binding site; other site" /db_xref="CDD:173782" misc_feature complement(58377..58379) /locus_tag="ClothDRAFT_1951" /note="putative nucleotide binding site; other site" /db_xref="CDD:173782" misc_feature complement(56832..58235) /locus_tag="ClothDRAFT_1951" /note="DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded...; Region: TOP1Ac; cd00186" /db_xref="CDD:73184" misc_feature complement(order(58047..58109,58128..58133,58164..58235)) /locus_tag="ClothDRAFT_1951" /note="domain I; other site" /db_xref="CDD:73184" misc_feature complement(order(57042..57047,57057..57059,57063..57068, 57075..57080,57693..57695,57717..57719,57729..57731, 58176..58178,58188..58190,58200..58202,58209..58214)) /locus_tag="ClothDRAFT_1951" /note="DNA binding groove" /db_xref="CDD:73184" misc_feature complement(order(56964..56966,58062..58064,58074..58076)) /locus_tag="ClothDRAFT_1951" /note="phosphate binding site; other site" /db_xref="CDD:73184" misc_feature complement(order(57195..57227,57309..57365,57369..57413, 57819..57824,57972..58034)) /locus_tag="ClothDRAFT_1951" /note="domain II; other site" /db_xref="CDD:73184" misc_feature complement(order(57414..57476,57501..57524,57627..57794, 57798..57818)) /locus_tag="ClothDRAFT_1951" /note="domain III; other site" /db_xref="CDD:73184" misc_feature complement(order(57006..57008,57078..57080,57084..57086, 57435..57437,57447..57449,57456..57458,57519..57521, 57765..57773,57783..57785)) /locus_tag="ClothDRAFT_1951" /note="nucleotide binding site; other site" /db_xref="CDD:73184" misc_feature complement(order(57519..57521,57693..57695,57699..57701)) /locus_tag="ClothDRAFT_1951" /note="catalytic site; other site" /db_xref="CDD:73184" misc_feature complement(order(56832..56948,56964..57008,57024..57095, 57144..57194)) /locus_tag="ClothDRAFT_1951" /note="domain IV; other site" /db_xref="CDD:73184" gene complement(58862..59677) /locus_tag="ClothDRAFT_1952" CDS complement(58862..59677) /locus_tag="ClothDRAFT_1952" /inference="protein motif:PFAM:PF05582" /note="PFAM: peptidase U57 YabG" /codon_start=1 /transl_table=11 /product="peptidase U57 YabG" /protein_id="ZP_05430091.1" /db_xref="GI:256005121" /db_xref="InterPro:IPR008764" /translation="MSMLKIGDIVTRKSHGQDIYFIVTDIQNKDSSKPVYILRGLFYR IIVDAFEDDLVKKDSRSTRINLRRDLTMARSNAYRQIFTSRCFLFSKPRQRPGKVLHI DSSESFLKMCRNLYKEAGITSREYLAPESEQPNIIKRALAETKPDILVVTGHDSLKKG SDPNLLDSYRNSKYFIECVKEARKYQPDYDKLCIFAGACQSYFEAIMQAGANFASSPG RININALDPAIVSEKVALTNKDNYVTPEEVSKLTISGSKGIGGIKTRGHLTVL" misc_feature complement(58934..59668) /locus_tag="ClothDRAFT_1952" /note="YabG peptidase U57; Region: Peptidase_U57; cl05250" /db_xref="CDD:164072" gene complement(59862..60848) /locus_tag="ClothDRAFT_1953" CDS complement(59862..60848) /locus_tag="ClothDRAFT_1953" /inference="protein motif:PFAM:PF00395" /note="PFAM: S-layer domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="S-layer domain protein" /protein_id="ZP_05430092.1" /db_xref="GI:256005122" /db_xref="InterPro:IPR001119" /translation="MTPMPTPTPTLEVKSDPYLSDLVVTGAKLKPAFVPDILNYEAVA EEDVRFVCIVAYARDDGAEITLNGVPVKSGSISHAVELKEGKNELIVKVVAEDGITSR TYRISVLLEALQLPTPTPDKSGNPFFSSLEDLLKENEVSPDGTKGGIFDDVPRGYWAE EYIQKLYEKGIISGIDEKTFMPGRPITRAEFTQIIVNSLKIPYREAGLHFNDVTEKDW YYKSVSSAAAFGIVVGRPDGSFAPNEFITRQDMAVVIAKFLEKKHDGNLEGMGKGLVF ADSGNISEYARDSVAAVVSQGLMVGKPGNMFDPKGLTTRAEAVTVICKLMKY" misc_feature complement(60276..60401) /locus_tag="ClothDRAFT_1953" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature complement(60093..60221) /locus_tag="ClothDRAFT_1953" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature complement(59892..60023) /locus_tag="ClothDRAFT_1953" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" gene complement(60814..>61141) /locus_tag="ClothDRAFT_1954" CDS complement(60814..>61141) /locus_tag="ClothDRAFT_1954" /inference="similar to AA sequence:KEGG:MONBRDRAFT_12738" /note="KEGG: hypothetical protein" /codon_start=2 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430093.1" /db_xref="GI:256005123" /translation="EPDTDAGAGTESDIDADTGTRTGADIDADTGTGAEPDTDAGAGT EPKPDADTGTEPKLDSSTDADTDSNASAKPCTGTGTNINTGTGTNTDSDSNANHDTDA DTDPNS" ORIGIN 1 taataataat gatatgagga taacagatga aatataaaat tttcacaatt ataatattta 61 tctttattac ctttataatg gtttcctgta ataataatat gaaaaatatc actacaagtc 121 cggataatga aagcacacca aacagttcgg caacagacaa tttgacaata gataatttca 181 caacagacaa ttcttcaaag tccgaacaat taatatctaa aaaggatatt gatgagtact 241 ttaacttata ttacaactat ttcaaagagc agaaaattga aaatagtaac tataccgatt 301 cgagtttttt cagatactcc cttgaattcc ccactgtatt ttttgataaa gtgactcttt 361 actttgccaa taattctgaa agactcacac ccagttatat tgaaatatca gtaccatatg 421 aaatagaagc attaagagat tttggattta agaagggtat gtcattaaat gatgttaatc 481 agatagataa atccttgaaa attgaagaat gcaaaataag ccacagtgat aataatataa 541 gctttattga gttaaaaata ggcaattaca tttatatatt aactgcgtct gacagtgaag 601 aagaaattgt ggatgtatac ataaaaaagg atggtacaaa tttaatagat gcagtttata 661 atgatattgt taatttgata gctgatttta gtgattatga caattgttac ccactttttc 721 tcactcgcgg gaacataaat catgacagtt atgaagatgt aattattact tttgaaatag 781 atactcctca ggacggcatt gaatcttatg gcaatagcag agtaacactt attctttttg 841 gaagcaaaga tggataccta aaatatggag aagtcgaagg cttgataaca tcccatggag 901 gtcttttagg caaaccaatt gtgtcaacaa atattgataa cggtactatt tcaataagcc 961 aatatggcgg ttcggcctgg cgatggaacg ttatatcaac ctatcaatat gataaaacag 1021 ataagcgaat atatttaacc aaacaagaag aaagccacta ctacaatgtt ttgcctatgc 1081 aagatactct tcagacaatc gttaaccatt ttgaagaaaa aatagatatt ttagacaatt 1141 tttatgaaaa taatcaaaaa tcaaacacag tatctaaaac actgggcaaa ttaataattt 1201 cttatgaaga gtttaactac tctgataata ttaagcaaaa ttttatcaat gacactatca 1261 aaaaatacat aaataaacaa atagaaaaaa ttaagaacat gggcgttgaa ggcaaattta 1321 gcataacagt cggtgaaact ataaaaaatg aaaaatttgc ttcaatatgt atttacacca 1381 atggtaatta ttacaatcac tcaaaagaaa ttaaaaatga tgaatacaat gaatatttcc 1441 atgatgaaga atatgtaaat attgatttgg tcaacctgaa agaagttgat atatttaatt 1501 attatacaat tgatgaaata gcacaaaaat tatacgatgt acatgtagaa cagggaaatc 1561 ctgaggacta ttctgtaaaa tcaaaagaag atatcgttaa tgttattaag gattcaatga 1621 acggcgctaa taaaggcaat aacaaatttg aatattattt caacgatttg tcaatcagat 1681 tagtactata tttacaaaat aaaaatgaag acattgtgga tgaacgggaa tgttctgtgt 1741 tgcgtacgga tgaattagtt gttaaaccta cattatttaa ggaatggttt gattcaaaat 1801 tgcaatagct acaataacta ttatatttgt aagggcaaca taaatgtttt ttcctgctta 1861 acgagtgctt attccttcgt ctatacatca aaaaaaataa atcttgtcta ttacggtagt 1921 aattgatgac taattataca ccgacggtgg caaaaacaat gtttttattc ttccaatcat 1981 atagaaataa ttaagtggtg aaaatgcaaa aaaattacta taaagtttta aaaataacta 2041 accgatactg agattaatgg atttatcatt gcattgaaat gctgtattag ccggagagga 2101 tgaaataatt tgaaagttgt catattggca ggaggaatgg gaactcgcat cagtgaagaa 2161 agtcatttga aaccaaagcc aatgatagaa atcggagaag ctcctattct atggcacatc 2221 atgaaatact attcatatta tggctataat gattttatca tttgttgcgg ttacaaagga 2281 tttttaataa aggagtattt cgcaaactat tatttgcatc tatctgatgt cacctttgat 2341 ttttcccggc aaaacaacat gattattcat aataatattg ccgaaccctg gaaggttacg 2401 ttggtagata ccgggttatg tactcaaacc ggagcccgta ttaaaagaat tcagaagtat 2461 attggaaatg aaagcttcat gcttacctac ggagacgggc taagcgatgt gcctctcaat 2521 gaattggtaa actttcatag aaagcacgga aaagtattga ccatgactgc aatacaaccc 2581 ggcggacgat tcggagtgct atcttttgga gaggatgact atacaatcga gaagtttagt 2641 gaaaaagcaa aagaacacgg cggttgggtc aacggcggat tcatggtagc ggaacctgag 2701 atttttgagt atttggatta cagagatgat ttggtatttg aacaggaacc aatgcataaa 2761 ctggcatccg gcggacagtt ggcagcatac aagcactttg gcttctggca atgtatggat 2821 accatgaggg ataaaataat gttggaacgt ttatggagct caaattcagc accgtggaaa 2881 gtatggtaag ccacatattt atcaaataat ttccgcagat ataacaatgt atgaaaacga 2941 taacacatga gaggtatggt aattatgaaa aatttttata aaaacaaaag agtgcttata 3001 acaggtcata ccggttttaa aggttcatgg ttatccgaga tattgctgca atttggtgcc 3061 gaggtttgcg gatatgcact ggaatcaaaa gaaagctcgg atttatattt aaatctgaag 3121 ctgcacaaaa acatgaactc atatattggc gacattagaa actatgacaa attaaaaaaa 3181 gtattcgata cattcaaacc tgagattgtt tttcatttgg ctgcgcagcc tattgtgagg 3241 gaatcgtata aaaatccttt atatacctat gaaaccaatg tcatgggaac agtcaatctg 3301 ctcgaagcag taagacactg cagttcagtc aggtccgtgg ttaatgtaac aaccgataaa 3361 gtatataaaa atataaatgt taacaaagga tacactgaaa cagactattt gtgtggacaa 3421 gaaccctatt caaattccaa gtcatgttcg gaattggtaa cctacagcta taaaaaatct 3481 ttctttgata ctgatgattc tccggctgtt tccactgcca gagcaggaaa tgtcattggc 3541 gcgggagatt tttcaaaaaa cagaattatt ccggattgtg taagagcagc attcagcagg 3601 aacaaaatag agatcagaaa tccctattca ataaggccgt atcagtatgt aatggattgc 3661 ttgtacgggt atctgcttat tggaatgaag caatactgcg acagaagtct ggcgggagca 3721 tacaatttcg gacctaaaga agatgattgc aaaaccacaa tagaaatcgt ggataaattc 3781 tgtcatgtct ggggtgacgg gttggactat tatacaaaac cggatgattc agtatatgaa 3841 agtcagatat tgatgctgga cagtagtaag tccaacaagt tattgaattg gaatcctcaa 3901 tatgatatag atcatgccat gcataagacc gtagaattgt ataaactgat ttatgaaaag 3961 aattttgacg aatatgcttg ttcacatata gaggattttt tcagcggagt atcagctttt 4021 aaaaacaaca gcccattatc catctctgca aaaaaatccg caaaaaacaa ttctctccat 4081 gaaaatcaaa tttgtgcaat gtaaataaaa aacaaatccc gtctcattat cttaataggt 4141 aaatatgttt tgcatttctt caaatgcagg cagcattcta tctctttccg acataatggg 4201 attatcattt ggccacggaa tacctactga atcccaacgg ataccagtgt cattttcggg 4261 tgaataaact gtagtgacct tgtagataag aatcgcctga ttacttttta cataaaaacc 4321 atgagccagt ccttttggaa tgtaaatcat atttgcctta tctgagttta agtcaaatat 4381 gtcatatttc ccacaagttg gagaaccaac cctcaaatca acaactacat ccataacttc 4441 gccgtgcaca caatacacta cttttgtatg ctctctggga ggtttctgaa aatgtaatcc 4501 ccttaacact cctttatgtg acacagaata atattcttca gcaaaattag tttccaatcc 4561 tgcctgagca aaaacctcct cgtgaaacgt ctttacaaac cttcctctgt tgtcactgaa 4621 aattctgggg ataagctcat aacacccgat aatttttgat tcttttatat ccagcatcat 4681 tattaatttc ctccggcatc tattcttgta ataaagtctg tttttttatg ataaaaaact 4741 cttgacctaa attttatcag gcactattca ggaaaataca ggctgttggt tatggtaggt 4801 aaatcatact agttcgatta caacttgcgg cgtaacttac tatttacaaa acttttaatt 4861 tgctccacca tgtaaccaca catatcttca gttattcccg gatatacacc aacccaaaac 4921 gtgttgttca ttattttatc agtattgctc aaattgcctg caactctaaa gccctcaccc 4981 gatgctctca tttcatcaaa gcacggatgt tttaaaatat tacctgcaaa aagcattctg 5041 gtttggatat tcttcgattc gagataactt actatttcat cccttgtaaa tccggcattt 5101 tctttaacag tcagtataaa tccaaaccaa ctgggatctg aatttttagt aggttcagga 5161 agcacaaata cgtcctgaag atctttaagc ccgtctttca gcaaattcca gtttcttttc 5221 cgtatttcaa taaactgagg caattttttc agctgggaac atcctattgc cgcctgcata 5281 tctgtaacct ttaaattata tccgaaatga gaataaacat atttatggtc ataaccgtaa 5341 ggaagctcgc cgaactgttg gctgaatctg ttcttgcagg tatcatcctt accggaagca 5401 caccagcaat ctctccccca gtctctaaag gattctatca atcttttcaa catagtatta 5461 tttgtatata ctgctcctcc ctcccccata gtcatgtgat ggggcggata aaagcttgaa 5521 gtcccaatgt ctccaattgt ccctgtatat ctccattcat tattataaaa gtatttggaa 5581 cctaatgcgt cacaattgtc ttcaataagc cacaaattat tcttatcgca gaaattttta 5641 accgtttcca aatcaaaagg attaccgaga gtatgcgcca ccattacagc ctttgtttta 5701 tcggacagag cctcttcaag gcgcgaacaa tcaatattgt aggtgggaat ttccacgtca 5761 acaaaaacag gtacggctcc atattgaata attggagcaa ctgtcgtagg aaatccggcc 5821 gctacggtaa ttacttcatc gcctctcttt attctcctgt cccctaattt gggtgaagtt 5881 aatgccataa aggccagcaa attggctgat gaacctgaat ttgtaagaga gcaagttttt 5941 acacccaaga attcagcaaa atctttctca aattgttcac tgtatttccc ggtggtaagc 6001 caaaattcca atgcagaatc tacaagattt ataatgtcat tctcgtcaaa aactctgcct 6061 ccataaggta tccgatcacc aggattgtaa ggcttatctt cttttttgtg cttgaaattg 6121 taatatttaa caactgcctg gtgtatctcc cgaagaagtt ccttttcttt tgcatttata 6181 tctggattca tatttacata gctcctttta aaattttatt tgagcttgaa attcagcggt 6241 ccggttatca tagaacagca tttacataag acatcaaaaa atcaggtttt aaacagaact 6301 ttagatttac tattctttaa gtttaatata actatatcca aatatcaata cagttaatct 6361 caattttcta tccaggatat aaacatttta caaggagcct gagatttcca tatgcaccaa 6421 aatgtttttt caaaaagaat attaagtttt aaatatgtgt aaccgatatt gtaagtaatc 6481 atagcacaat ctgaacaatt gtaaataaat ccagctgctg tttgtttcat taaaatatca 6541 tttaatgagg tttaattatg acaaaaacaa tcattacagg tgcatccggg tttgttggaa 6601 aatcattggt gaaggaactt tctgcaaaag gatatgaagt tctcgccatt atacgcaaca 6661 aaaataaagt atccgaattt gatgatttaa gcaatgtatc tgttgttgtt tgcgatctga 6721 gagatataag caatcttaaa aacttcctac cgaaaaccga ctacagttat ttctttcacc 6781 tcgcatggga aggcacttca ggacctgaca gagaagacta tcacaagcag ctccaaaacg 6841 tagtatatac atgcgaagca gttaaaacag ctaaagagct gggttgcaaa aggtttatat 6901 atgcaggcag tttaatggaa tatgaaagca taaagtacat tcccatcaat ggctccatcc 6961 cggtaaaaaa ctatatatac agaactgcaa agcttaccgc gcactatatg gccaaatcat 7021 tggcagtaga tttgggaatt gatttcgtca ccggtactat atcaaatgcc tatggtgaag 7081 gtgaaatatc tcccagatta atcaactcca ccatcagaaa actcctgaaa aatgaaaaaa 7141 caagctttac ttccggagag cagttatatg attttatata cattaccgat gtggcaaagg 7201 catttattgc aattgcggag aaaggcagag cctatggaaa ttactatata ggaaacagaa 7261 ctcaaagaaa attgaaagat tatctgattg atataaaaaa ctgcattgat aaaaacatag 7321 aattgggatt cggagaaatt cctttttacg gagcaagtct cgattacacg gaattcgata 7381 caaatgcttt atatgaagat actgatttta aatgtgaagt tgattttatg gagggaataa 7441 aaaagacaat aaaatggatt gaacaaaaca gctaaaattt gtctgtcagg atacactttt 7501 agacaggagg aattaagtta tatggaagat aatataataa ttgttgacac aagcatgata 7561 gaagcaccaa aaccgggcaa taccttgtat gaaaccagaa gaaattttgc ggatagttat 7621 aaagtcttta acaatcagat agccatatct ataatagcat ataacagatt ggaaaaaaca 7681 aagaaatgta ttgagtattt attcaaatat accagtcaca tagatttcga attaatccta 7741 tgcgataatg gttcaaccga cggaactttt gaatttttta aatctattga ctaccccaag 7801 aaaaaaatag ttagaattac aaaaaattta ggtgcctttt ttgctgcaaa tctaataata 7861 gatatggcga agtgcaaata ctatgttgcc atgacaaacg atgcttatgt tacagaaaat 7921 tggcttgata atttgctaaa gtgtattgaa tcggatgaca gaatagctta tgtttcaccc 7981 atgtcatcaa acatgagcaa caatcaggac ccaggtctta agtttagcag tctggaagaa 8041 atggaaattg tagcatcgca attcaacaag tctgatccta gaaagtggat ggaaagaaaa 8101 aggattgtag gtgtacttgc atgttacaga aaagatgcat tggaccaaat cggtaaatat 8161 gacccgggat tttttcacga attttccgat gacgattttg cttttagggt aacccgagcc 8221 ggatataaac tcgttttatg cggagatacc tttattcatc atgaccatgc tgtttttaac 8281 atggaagata aggatcctga aacaaccaaa caatctttaa gaaatggcag aaaaaatttc 8341 aaagacaaat actatgggat tgattcctgg gaagacttac tcaattttga aaccccatta 8401 ataaatatgg cttcatatga aaattccaac ggtgaaaaca acgtattggg aatagacaca 8461 aagtgtggaa ttcctatttt agaaattaaa aataagttga gatttaacgg cgctgataat 8521 attaaattat atgcatttac aacaaaagca aagtattata atgatttgct tcatacatgt 8581 gaaggaaatg ttaattgcga cagaatagag ttcttaaatg aatattatgt taaagatagt 8641 tttgactata tcattttggg cgaagcactc aattcttata aagaaccgtt taagttgttg 8701 gaaaatatca tagatttgct ccaaccaagc ggacaagctg tgataaagtt aaaaaataca 8761 cttgaaataa gaactttatt atcactatat ggacataaac aaaatttctt tgaagaattg 8821 ttgatacact tgtctataga cgatgtaatt gcatttctaa atcaaaaaaa catatcagat 8881 gttaaattat ccggcatcac ctataatgtt gacaatagta ttaatacatt tgtgaacaat 8941 acagcaagtt cagttggaat ttctcccaac agcttaggac atttatatat aaacgaatat 9001 ttaatttata taaaaaagta aaaatgacag caaatattaa taaatataat aatactacag 9061 ggaaggaaga aacagctatg aaagcaaaaa aaataaacgg acaggcagta aacggaaaga 9121 gagaaatgtt ggcaagtaag ttgccgctgg atactccata ctcaataact attttcccta 9181 tatatgcttg caattttagg tgtaaatatt gtcttcattc attggaaaaa gacgaaagag 9241 aattcatttc agatacaatt accatgccat gggaaacata taaaaaatgt attgacgata 9301 tattaaaatt cccgcacaag gttaaaatgt tgcatctttc aggattagga gaacccttgt 9361 tgcataaaga catcggcaag atggtggcat atgccaatca aaagggcgtt gcagaaggaa 9421 tagatattgt cacaaacggg tcaatgttaa caaaagagct cacacatgaa ttggttgatg 9481 ccgggcttac agtattgcgt atttcccttc agggcattaa tgaagaacag tataaaagag 9541 aagccggtat agatattgat tttgatgaat tttataataa cataaaatac ttttatgata 9601 atagaggaaa tacaaagtta tatattaaag ttatcgatga aatattggat gacggtcagc 9661 aagaagaatt tttcaatatg tttggtgaca tatgtgatat cattgcaata gaacatttat 9721 gtccatttgt tgacaaaata aattatacag acacttttaa ccaaaatgaa ttttatgtta 9781 cgatgaacgg taaccaagta cccaatacca atatttgccc gcaaccattt tatagtttgc 9841 agatatatcc tgacggaaaa tgcataccgt gttgtaccgt agaaaaacca atagttgttg 9901 gggactgctt aaaacaaagt ctggtgcaaa tctggaacgg agatgttatg aatagcttca 9961 gaaggctaca attgcagtct aaaaaagaaa ataaccgagt atgtgcaaag tgtcagcaat 10021 ataagtacgg tatgtttaaa gaagatatac tggatgagta tgcatctgat ttactaaaac 10081 tatatcaata gaagaaggca ataaactatt tagtaatcct tggaatcatc tctgttttag 10141 ttctatgtac tgacaatttt ttgaaaatta gtttaatatt ttaaacatga aacaaaagct 10201 aacgatttct tataatatct aatatgtaga tgaggtgtat tataaatgtt gtctgaatta 10261 gtacgattat tggatgattt tgaaaaaggt aatttggatg atgaaaaagg aaaatttgta 10321 gaattagaag gtaaaagcat cttactttat ggagcaggaa atataggtaa aagattatat 10381 caaaatttaa aaaataacaa acttaatatt gttggtttta tagatagaaa tgaaaatttg 10441 gataaatcag cttatgaggt ggaagtttac ttacctcaaa gcgaaaagct aaataagtat 10501 aaagaaaatg gcattgtcat cttatccgca ttattttctt taaatactgt aaaagaaatc 10561 aaaagttcat tacatttatt ggggtttaaa aatgtgtttg cacttcatga aataaacttt 10621 tcaaaaataa atagcgtggc gttttatgaa catttgtttg atggctccta taacaagtta 10681 gacctgatag ggaaagacag gcaaaagatt attgacgctt ttcaattgct tgaaggacct 10741 aaagaccaga aattatatat agattatata aaagcacatt tgacaatgga ttttacacaa 10801 tttgacgacc cggaagatat tacaggacaa tatttagcaa aggatataga atacaataaa 10861 gattatagta ccttcattga ttgtggagga tttgacggag atacaattaa aaatttagtt 10921 gagcataatg taaatatcaa gaatgttatt gtatttgagc cgcaaaatga attatgtaaa 10981 aaaataaaga attatattga taatatcaaa ataatagaat cctctgttat atttccttgc 11041 ggagttcatt cagaatttgc aaaattacga tttagtactt cttcggatgc tccctctgca 11101 tgtaaaatag attccggcgg aaatgatatg atacagtgtg tagcaattga tgatgttctg 11161 aaaaacatca gacctacttt tataaaaatg gatattgagg gtgcagaatt aaatgcatta 11221 aaaggttgta aaaatacaat tgtcaagtac cgtcctcaac ttgcaatttg tgtatatcat 11281 tccttatcag acatttggaa tatacctttg ctaatccaca gttactacag tggatataaa 11341 ttttatttaa gaagctataa ctttatgggg ttagaaacag tattatatgc cttttaggag 11401 aaagaggtaa gataatgata aaggttgtgc acataactgc acatttaggc ggaggaattg 11461 gaagaatact ttcgagtata gctatatatt cgcaaattga aaaagaagtt gaacatgtta 11521 ttgttacgct ggaaaaaacc gagaattctc attttgaaca gttactgaaa gaacacagca 11581 taaaagtttt cctgcaaaac caatgctgtc taaaacaaat attacaagag gctgacattg 11641 tcgaagtgga ttggtggcat catcctctaa cctctgcgtt tatgcataat tattttaatg 11701 atatagaatg cagattgctg atttggagtc atgtttcagg ctgtacctat ccgtatataa 11761 aatatgaact tattaaatgt gcagataaat ttgtgttttc cactcccttt tcatttgaaa 11821 atgagtattg gtcaaatgaa gaaaaagaag aagtcatgaa aagagtagaa ataatagtaa 11881 gctctggaat agattttgat gctcctgtaa agaaaaagcc acatcacggt tataatgtcg 11941 gctatatagg ttttttaagc tattccaaaa cacaccctga ttttgtaagg tttctggaag 12001 ctgctgccga catccctgac atatgtttta aagtagtagg tgatacagca tacgggaaag 12061 aattgattaa agatgttcaa aattccaagc ttgtacgcaa caaggttata tttgaaggtt 12121 acgccctgga tgtgaaagaa aagtttgctg aatttgatgt atttgggtat cccctaaatc 12181 caatgcacta cggaactgct gaaaatgcgt tgcttgaagc catggcggca ggagttgttc 12241 cggttgttct gaatcaatgt accgaaaaat acatggtaag gcatatggaa acaggaataa 12301 tagtaaacag tatcgaagaa tacggagctg cattaaggtg gctaaaagat aatgcggaca 12361 agagaatcca catgggcaat aacgcttctg aatttgtcat taaaaagctc catattcgcg 12421 aaactgtcaa cagattaaat gcctgttatt ctgatatgat gagccagaat aaaaggctgc 12481 atgatatata ctctgcaata ggaactaatc catatgaatg gtttgttagt gcttattggg 12541 gtgatgtcaa ttgtttggaa ggcaattcgt ttgccgaaac aaagggctct gccaagcact 12601 atttaaggta ctttccggaa gacaaaatat taagaaaggt tgtggaaact aatgaaagcc 12661 gaatttaagc cgaattatga cacaaacaga aagaagctgg ccgatattat acctcttgct 12721 gcaccgttta cggtgtatat agaacaaacc aggtactgta atttcaaatg tttttattgt 12781 atacatgcca caagagataa agaggacgga gaatttcgca agctgggatt ttcggtaaag 12841 catatggatt ttgaaatgta caaaacaatc gtcagtcagc ttaaaaaatt tacagaacca 12901 ataaagagaa tagtattttc aggtctgggc gaacctctaa tgaatcccag gctgcctgaa 12961 atggtcaagc tcgctgtgga agcaaaaata gccgatagag tggaaataat tacaaatgga 13021 ttattattaa caccggaaac atcaagaaaa ctgattgatg caggaatcac aaacattaac 13081 atatccgtcc agggtgtaag caaggagaga tacaaagaaa cttgcggagt agaaattgac 13141 tttgatgagt acgttaagaa ccttagttat ctatacagta ttaaaggtaa tacacaaata 13201 tatataaaag caatagatgc tacactaaaa tccaaggaag aagaagaaaa gtttttcaat 13261 atttttggaa atatatgcga caaaatttat atagaacatt taattgtcat gcagcagcaa 13321 atgggtgaac tcaaaaaaat agtggacggc actaaaaact tttacaatga ggaattggat 13381 ttaaacagaa aagtatgtgc ccaatctttc tatttcttac aaattggatg cgattacgat 13441 accttcccct gccctgtacc gggtttgcca aaaagtttat ccatgggaaa tataaaggat 13501 aatactataa aagaaatttg gaacggtgaa aaaagaagag aacatttaag aacaatgctc 13561 agctatcaga aagacagcat acctgagtgc aacaattgta catgctttaa tgcgattaac 13621 aatccactgg agaatttgga cccggatgcg cccagacttt taaaactgtt tgaataaaag 13681 tgtaaaaatt tgacttaaaa ggagaataaa atggcatcgg aaattaaacc catttatgga 13741 acagaaagaa taaaactgtc taaagtcatt cctttaaaaa caccttttag catatttgtt 13801 tttccgacaa cctattgtaa tttcaagtgc gtatactgtg ctcattcttt gggattggac 13861 gccatgaaaa agacttatga ttttgtccct gaaaacatgt caatggagac atacggaaaa 13921 tttattcacc aaatgaaaaa atttccggac aaactgaaaa tgttatgttt aatgggacaa 13981 ggagagccat tgattaataa agacattcct gtcatggtaa agatggctaa agatgcagaa 14041 attgcagaaa gagtggaaat tatcagtaac ggttcactcc ttgacaaaac aatgtcagat 14101 cgattgatag aagccggttt ggatacctta agaatctcac tgcaaggtct aaattcaaaa 14161 aaatataaag acatatgcgg cgctaatatt aatttcgatg attttatgga caatatacga 14221 tatttttatg cacataaaaa caacacaaat ttatttgtaa agattatgga cgtatgcctg 14281 gaagaaggcg aagaagaaaa gttttaccgg ctttttgaag attgctcaga cagaatgtat 14341 atcgaaaaaa tgctgccggc atacgatggt gtggaaataa ccaaaaatat gaaggtagag 14401 tacgaccgat acggaagaaa acatgaaaaa agaaatgtgt gtcctctgcc gttttatatg 14461 ttgggaattt tccccaacgg ggatgtggaa ccttgtgaca caatttataa gcctatagtg 14521 ctgggcaata taaacaactc cgaattaatc gacatgtgga acggagaaaa attaagagaa 14581 ttttggaaat tacaattaaa aggcaacaga ttacagaacg ataaatgcaa agtatgctgt 14641 gctccggacg atgtttccca tcctgaagat gtattggacg atgatgttga agaaatatta 14701 aaaagactgg aaacaatgga gagtaatata tgagagctgt aagaattgac ggacaaactc 14761 cgggcggaaa acggaataaa ttaaaggatg cacttccttt agatacacca tatatggttc 14821 aattttttcc gatatatgcc tgcaatttta aatgcggcta ttgtattcat tcggtgcctg 14881 ttagccaaag gcgttatata acggataaaa ccgcaatgga ctttaaccta tataaaaaat 14941 gtattgatgg cttaagcaag ttccccaata aagttaaaat gattcgtttt gccggtaccg 15001 gagaaccttt attgcacaag gatattgcca agatggttga atacgcagtt aaaatgaacg 15061 tggcagaagc agttgatatt gtaactaacg gtttgcttct cgagccggat ttgtctgata 15121 aattaattgc tgccggactg tcaaagctta gagtatcaat acaaggtgtt acatctggaa 15181 aatatgaaga gatttccggt aaaaaagtcg gcatatcaaa aattgtagat aatttgtctt 15241 atttttataa tgccaagcaa aaaagcgaaa acaccacaca gttatatata aaaataatcg 15301 attgtgcatt ggaagaagga gacgaggaaa aatttttaaa tatgttcgga gatatttgcg 15361 atattatcgc aattgaacat cttttgccgg ctgtcccgca aattgagtac aaagacaaat 15421 ttaacatgga ttcggataat cttttaactc aaaacggaaa ccgtatttta gaagctcaag 15481 tttgcccaca gccattttac atgatgcaga ttaatccgga aggaaatatt gtgccatgtt 15541 gtgcaatgga aacagccaaa gtaataggaa acgttaatga caatgattta tacagccttt 15601 gggtgggtga agaattcaac aaattcagaa gaaacctgct gtcactaaac aaacaaatat 15661 atcccgtgtg caaaagctgt gaatcttata agtactcaat gtttgaagag gattttttgg 15721 acgatgccag actgaaattg ttggatttat atgtttctcg gtaaatttat acttctaaac 15781 aattaaggag gataaagctg caatgatacc taaagtcatt cattactttt ggtttggaag 15841 aggcaaaaaa aatgacgtaa tcgaacgatg tatggacagt tggaaagttc acttgccaga 15901 ttacgaaatt aaagaatgga atgaggataa ttttaatgtg catatcaata attttacttt 15961 acaggcttat cagatgaaaa agtgggcttt tgtatccgac tatgccagat tacatatttt 16021 atatcattat ggaggtatct atttagatac agatttggaa ataacaaatt cattagaccc 16081 gtttttagat tatgaaggct ttatgggttt ttttcaaatt ttgatattag cggaggaatt 16141 attggagcag caaaaggaaa taaattcatt aaaaaactgt taacttatta tgaaaataaa 16201 aattttattg atggaaatgg aaaaatcgac gaaaaaacta atgttgaaat tattactgag 16261 atttccaaaa aacattttgg ctttgtagga gaaaaccaaa cgcagcaaat actggacatg 16321 actattttcc ccaaagaata ttttacagtc agagatgtta atgtaaaaaa ttatgccatt 16381 catcactata atgcttcctg gctttcgcat gaagaaatga ataaacattt aaagagctat 16441 agaaagtatt atgagtttac agttaaatgg cttgataacc ttattaataa caagatagat 16501 ttaacacctt acaaaaataa atgcattgcc atatttggca agggatatat tggcgaactg 16561 ctcgtaagct atctccaaaa taataatgtg ccaataaggc agataataga tacaaagttt 16621 gcaaatgaca cctacaaaga tatccccatt gtatcatcgg atacaattag tgatgaagtt 16681 aatcttataa ttattacgcc cattcatagc tttgaaagca tatatttatc gttaaaagag 16741 aaatcttgcg cagatattat atcaattgag aatctgttat cataagattc aaaaaaagaa 16801 tctcctccgt ggatatcatt tttgcaattc ttgccatgga ggaaactttt aatatttaac 16861 aattggcttc ttttatgact tacgtttctc aaacaagcac tttttaaaat cattgttttg 16921 aagagttttc ttggtttaaa ttattctttt atcacttcca atttcataaa aatagccaaa 16981 gctttaaagt gctttggcta ttttagcgtg cgcccagcaa attatttctt gtttgcaggg 17041 aagtctgaaa tcctgcgtaa tatatacctc ttcagatatg tcaaatccaa tgagcttact 17101 gaaccattgc cgtccacatc cgccgccatt aagccgtatt cgtctaaatt gaaagcactg 17161 tttcgcaaca gatatccctt caaatacata atatccgttg aatttattct tccatcttta 17221 ttaacatcac catatttgat tttcactttt tgaataactt caaacattgg tctgccattg 17281 gcgcttctag ataaagcaca caatttaccg tctacataaa acagcttcaa tatctctcca 17341 gttgacgaca acgtatcaat tcctgaaaag tcttcataat tataaacgta aatttgattg 17401 ccgccaactg cagtataaaa cctgttttct tccatattaa atgcaatatc tgtaaatttt 17461 ttatccagag taaaagcaaa cttcatatct tcatttacat tctcattgca tgtaaataca 17521 actccagaac tattaaacaa gtatttgccg tcaggagata tcttaaattt ttctgctaaa 17581 ggataactgt catagtatgt tgaactataa gaagacacaa acttaccgtt atcaacattt 17641 aaaactttat agtctattgg cattatatca ataggaatag cataaatcct gtctagggtt 17701 ggattgtact cagacaagca ttcattattt actaattccg aatccatgaa ttctttagtg 17761 gaacgtgaat agctattaaa ataagccttt tgaggctctc ttgaagtcac atataagtaa 17821 ccattctttc ctgcaaaaat attaaatggc ctaattttga tatctatttt ttcttttaac 17881 tccacagttt tggtatcaat tactgctatc atgccatttg ggccttccgg cagccagtat 17941 aaactttgcg aatctgttag cgctgtaaca aacagctcat tatccagata ggccatcctc 18001 cctattttgt cacctatata ggcctatctt acttccccag tctctatatt aattgaataa 18061 actattgaat tggcactatc tgcagcaaaa atcaccggtt ccgtcggatg ctatattgca 18121 tcgctacttt tagtaccaat cggaaacttg aaatcttcaa actcgttttt gggtatcaaa 18181 ctttcctctg cggcttttac aggaaaaact gtcagattag tcaaaaaaga agacattaca 18241 aaacagatta acacaaacag ctctaatctt tcatttgatt taggcatcct aatatctccc 18301 tccaacattt atataaagcg ttttattatg acgtatgtat attaacaata taatatttat 18361 gtcaaaatgt ccatattatt acactataca tttatttacc tatccgaatt acattccaag 18421 aggctctgcg aagcatactc gttaaaatac catcatcaaa tgaggattta tccgaatttt 18481 tcggatatac ctcctcacca tttacactat tacggatttt tagatcttga tgctccaaga 18541 caatatgctc cagcagacga taatctttca tacccctgac atccgataca agaacaatat 18601 cctcatgaat atttctgtta actgcaaaga ttgtgacttc ttctttttct tcattgtaaa 18661 ttgcaacact ttcaatatcg gtaacatctt catgttttga agtatcatga agcggactgt 18721 taatcaccgg ttgaagtact attcctctgc catattttga agcatgcata aacggataaa 18781 atatggtctg cctccaagcc gccccgccat ttctttcagt cacaataggc gcaattacat 18841 taatcaactg tgccaggcag gcaattttta ttctatcggc gtgtttcata agggtaatta 18901 gcatcaaacc gacaagtaac gcatcttcaa acgtatatat atcctccagt aaaggaggcg 18961 ctattctcca tggttcgttc tgcataatgt ttgcatcttc attatttgag tgataccata 19021 cattccattc atcaaaactt aggtatatat ccttcttgct tcttttcttt gcttttatat 19081 aatcacaagt ggcaatgaca gaacgtataa aatcatccaa atcatcggat tttgccaaaa 19141 aatcagctgt gtcattttct ttattcccat aatactgatg caatgatata taatccacat 19201 aatcataagc ataatccaga actgttgctt cccattgggg aaaagtgggc atgtctttgg 19261 aggaacttcc gcaggcaacc aactcaattg aagggtcaat cattttcatg gcccttgcag 19321 tctcttcagc aatccggccg tactcatcca ttgttttatg cccgacctgc cacggaccgt 19381 ccatttcatt gccaagacac caaaccttta tgttgtgagg ttcctttact ccatgtttta 19441 ttctcatgtc actatatttt gaaccacccg gatgattaca gtattccagc aaattacatg 19501 catccgaaat ccctctggtg ccaaggttca ctgccatcat tatctcagca tttacttttt 19561 tgcaccattt tgcaaattca ttaatcccaa cctggttggg ttctatactt ttccaagcca 19621 aatccaagcg tctgggccta tcctctaccg gcccgactcc atcttcccag aaataattgg 19681 acacaaaatt gcctcccgga taacggataa ttggcacatt caattctttc accagttcaa 19741 taacatcttt acgaaaaccg tcttcgtccg atttggaatt tccaggctga tacagtccgt 19801 catatacggc ccttcccaaa tgttctacaa aagagccgta gatacgcttg tcgatctcgg 19861 caattttata atctttgtca acggtcattc tggctttttt catttttgta cctccaaaga 19921 attaattatt tatcaaaaat attatttgct gcaagttgcg ctcggatatt attttcggtc 19981 cattctattt cattataaca tgcttgattt caattatgct ttaaaataaa agtctcatcc 20041 atgcggtgag actttccaaa tcctataaaa tattgcttta tgaaattgct ttgcacaaga 20101 atcaagggta gtcagtcaga acggaaattc ctttaataat ctgggagttc atctctgtct 20161 gtaagtcaat aatgacaagc tccttttgga atcttgttct atgaattcct tcacgatata 20221 tatcttccat tgactttgtt cttttatatc ccctttgttt aagcttttct gccgcttgtt 20281 caacactgtc gcctaaacgt atcccaaaaa cgtgatagtc tccgccgtta atatttattt 20341 gcgtcaaccg cctgtcgctt gcgtctttcg gtatcttaaa ataatagccc cgaacatagc 20401 cgtcatctgt tacctttgac ccgggcatat catcattaaa atacttggct ctttcctctt 20461 aaagcccggc aaattcaagg tattccatac ccataaagct gttagcattt atctcttgcg 20521 cttcttgtat tgttttctca accagcttta tgcttgcatt ttcttcatat tttacaaaaa 20581 ccagagtgcc taataacaaa aataaacatg ttaatataat aattgttatt gcctttttca 20641 taattattct gccctaatct ccatatctct tttcactgat atttcatctt gcattaatta 20701 tttcttgcat acatttattt agaataaaat ataccacaac ccactataaa aatccattcc 20761 tttttgctta ttatccgaaa atgattaatt gtatcatttc ctgtcaaaga aaaaatgcct 20821 tttgcatgaa tcatactttt ttcggcatga aataatgcaa tataactaac ttctgtgcaa 20881 aaatgaataa ttagaaaacg gaggaatatt catgctgcaa attgcgctct gcgatgacaa 20941 tacaaacgat ctatccacca tgatacatct tttggacgaa tataaatcat caaagcagcg 21001 gatttgaatt aacttcggct ttagataaag gcaagcagtt tgacatatat tgcctggata 21061 ttatgatgcc gggttttaca ggcattgatt tggcaaatga aatccgaggt tctgacaaaa 21121 ccgcaccgat tttatttttt acctcatcgg ctgaatttgc attggaaagt tattccgtaa 21181 gggccgctga ctatgtatta aagcctgtct cgaaagagaa actcttttta acttttgatg 21241 aacttttgga acagatagaa gcacaaaaaa aggaaaatac aattattgta aagagctgcg 21301 acggcatcta aaaaatatta gtttcaaata tagtttatgc agaggtcatt ggaagaagtg 21361 tgttgtatca cttgatatcc ggaaaagttg tggaatgcac ggagcctttt tcaaccgtct 21421 gtaataatct cctgaaataa gggtgtttta ttaaaaccca ccgctcttat cttgtgaaca 21481 tgcagtatat aaacacaata ggaaatcatc aggtgaccct gcaaaccctt acttctgttc 21541 ctattgccca gggaaaagca aaggagatta agcataagta cctgaattat caaatggagg 21601 agtaataatt aaatgataga aatcttgttt ggtacggcga cagcggtcag tttcgccgga 21661 atggaacgca cacgtaaaaa ttatattgcg gtcggctgcc taactacggt tttatttttt 21721 ttgcaggtca tatgcttaaa tgcatgggat attgatgtga catttaaatt gtatccgctt 21781 ctgtcccact tacccattac tgttttcata gtggcatatt taaagcgtcc atggctgatt 21841 tcactaacca gtgtgcttgc atcctttctg tgctgtcagc ctccccgttg gatcggtacc 21901 gcccttggcg aagtttttga cagtgtttcc ataaatcacg tcagctatat tgccgccgcg 21961 tttttaacat actgtttcct tcgaaaatat gcagtgacat cagttcggca tctgatagaa 22021 cgttctgtca gttcctgcct gctttttggc gccatgccgg ctttttacta tctgttcgaa 22081 tatgttggat tcccagttta agcaggcaca aaaagaattt gaatcactac ggcagatgca 22141 aaaaactacc gcatcctacc gacacgatat gcgtcatcat tttgctcttc ttcagagtat 22201 ggcatccaaa ggaaacatgg aagatatcaa agaatatctg cagaccgtgc agtctgactt 22261 ggacgccatt actcctgtac gtttttgtga aaacgaaact gtaaatttaa ttttgtcctc 22321 ttttgccgcc aaagcgaaac agtcggaagt caggctgacc atagatgcaa agctaccgga 22381 ctcttaccct ttcagcgaca ccgagctttg ctccctcttg tcaaacaccc tggaaaatgc 22441 catacatgca tcaaagcaaa taaccgacat cagtaaacgc attatacatc tgcgcatgtt 22501 ttccaggaac aacaagctgt gcattgacat tcgcaacagc tatcaaaaag agccggtttt 22561 tcatcatggt ctcccggtgt caaaagagca gggacatggc tttggcacaa aaagcatggc 22621 tcatatcgtg gaaaagtacg gcggtgtatt tcaattttca gtcaaggatg gttggtttat 22681 atttcaagcc acaacatgaa gatttttata atattcgtaa tataaaggat aaaaaaatat 22741 aacgtattca aaggtcaggt ttcataaaaa tgaaccttgg ccttatcttt gaattattat 22801 atttttttga taaaaataaa tagaacaagc aaaaaaaata tttttaccgt tactgtgagt 22861 aattttatgc gtataatgat atgaaaacat cacataaata gtgaaaatcg tacgatttaa 22921 taactaactt catctttttg aaaaagcttt ttatgtttat taaaacaagg ttttggtaat 22981 aagatttata gaataataca agctttttta aaagaattat atgattggtg tgttaactat 23041 gaacaaagaa cgagacaata tattaattga aagtacctta aaaggcaata taaattcttt 23101 tgaggaattg atgacgctat atcagggaaa gctgttcaat tttctcttga agatgacctc 23161 ctcccgggag gacgcagagg aaattaccca ggaagtattt ataaaggtat ataacaacct 23221 gtataagtac aacaacaggt ggagtttctc cacttggatt taccgtatag ccataaacac 23281 actccggagt gaatatagaa aagcaaaaaa tgtaaagagt gttgactatt acacaaacgt 23341 atctgagctg cctgcaaact tcagtgatta tcccgagctg gcctatgaaa tgaaagagcg 23401 gcaaaaggaa ataatcaaac ttatcgacga gcttaaggaa gaccagaaaa cagcgttgct 23461 tctacgatat atgcaggatt tttcttttaa agaaatcggc gacatattgg gaatctctcc 23521 tgaagctgca aagatgaaaa tccagagagc caagcagagt atttgcaaaa agtatgaaga 23581 actcgaaaag gacggtggat aaaaatgaaa tgcaatttta attttgaaga cataattaaa 23641 tattccgaaa atcatctttc ggaagaagag aaaaagagaa ttaaagagca tctggatgta 23701 tgtgaaaaat gccgaaaacg ctatggcgta ctgaaattta cagaggctta cgcaaaagac 23761 agttccatga caagtgaaag catcactaaa aatgtgatgg aaacaattga cgtaaacaga 23821 tacagcaaaa gtaaaaagtt tttgttcggc aggaattttt acagagccct gcctgttata 23881 aaaccagttt tggcatccgc ggcagtattt gttgtggtaa tggtgggcat aacaagtttc 23941 ggaagtctca gaggattaat caacaattcc ggcgatgtga aacctaatcc aaccaatccg 24001 attgccaatt ctcaaaacac aaacccggcc gctttgcctg aaagtacagc cccggcagtt 24061 caaaatcctg tggaaaagaa ggtaatcacg ctttactatt caaattccaa tgcggataaa 24121 gtggttgcag aaaaaagaga agttgaaata agcaaagata cacaaataga aagattggtg 24181 tttgaagaat tgcaaaaggg tccgaaaaac gagggattag ttgccacaat accaaaaggg 24241 accagacttt tatcagtatc caccgaaaac ggcatttgca cacttaatct ttccaaagag 24301 ttcgttgaca accatcccgg cggaacagca ggtgaaacaa tgactttatt ttcaatagtc 24361 aatacaatga ctgagcttcc cggtatcgag aaagtacagt ttcttattga aggccaaaaa 24421 caggatgcat atatacatgt tgcatttagt gaacccttta aaagaaacaa cagtattatc 24481 caaaagagcc caagtgagat aaaagccgaa gttgaagcta agtctcagga agcgattaag 24541 gctatcaagg aaaaagatat ggaaaagttg gcccaaatgg tacatcctga aaaaggtgtg 24601 ttgttctccc cctattccca tattgaattg gaaaaacata aagtatttac aaaggatcaa 24661 ttaaaaaatc ttatggagtc ggaagaagta tatatctggg gagaatatga cggctccggt 24721 gacccgatta agttaacctt tgcccagtat ttcgacaaat ttgtatatga tcatgatttt 24781 gcgaacgccg aaaaagtggc atacaatgaa atacagcaat ctggaaacac aattgtcaat 24841 atttctgatg tatatccgga aggaaagttt atggattatt acttccccgg attcactccc 24901 gaatatgacg gaatggactg ggcaagttta agattagttt ttgaggagta tgacggccag 24961 tggtatcttg tatgtattgc ccatggccaa tggactattt aaaacattag ctttgcatat 25021 cttagttttc aaattatacc gttcgttggc ataatgccag gaacggtata atttttcata 25081 ccttgccctt ttccacaaaa acagtaaaag taccatcttc attattgaca acatcaagca 25141 ctctatgccc ttcttccttg aaactccttg gcacattcaa aataggttct ccctcattca 25201 tcttaatttc aaggatttgc ccctcttcaa gttcctctat ggcaatcttt gccttcacaa 25261 aagtcatggg acaaacaaca tcagtgatat cgacaaaagc atcagcttta atatcgctca 25321 tatccattcc tccattccaa acggttcctg tattctcatc atcccgcttt caatacttct 25381 tcaagcctgt ttttaagcaa atcccagcct actctgtcca aggtattgcc aaatctttca 25441 ccgggctttc catgctcctc aaaaaatgcc aaagttgctt caataacctt atgcaaatcc 25501 tcttttgaga aaataatagg caaaagctgc tttccgactg ctattctgtt gccgaacaat 25561 ccgccaaaat acacgataaa cccgcctctg ccttcccatg cacttgtagg gcacaccttg 25621 acgcatttgc cgcaatagat gcaatccttt tcattgaatg tcagctcttt ttcctgcttt 25681 ttcacctcaa tgacctttgc cgggcaaact gcctgacaca atccgcaata aatacattta 25741 tccttaaccc aacttggcat cattccgccc ttaaccccaa ggtcgttttc ctccgccttc 25801 aagcaattat ttctgcagcc ggtaataccc aacttaaact tatggggcaa ttcacgggca 25861 taataccttt catcaaattc cctggcaagc tccgttgtgt tgataagccc gctgggacaa 25921 ataacagccc cctgacatgc ggtaatcgtt ctaaccctgg gtccgcatgc accgggctga 25981 agccctgcct tggcaagctc ctccttgaca gcatcaatat cctgaagctt aatatacgga 26041 atttcgatac tctgtcttga agtcaaatgg atatagcctg caccgtattt ttgcgctatc 26101 tcattcacct ttgcaagctg ctctgctttt atctgacctc cgacgattct gaggcgcagt 26161 gaaaagcggt ccttgtcaac ctgcttcatg aatccgcctt ttttcagttc tttataatca 26221 acatttgcca cctatgcttc ctcccccaca atagacaact cttcctgagt tgcctgtcct 26281 gatgaaatat taaagctctt tagcaccggt gtgtcgtcct ttagtgataa tatcaaataa 26341 cttgcctttg gatcaaaggc aagccttatg tcctcttccg agggacggga tggcgttgcg 26401 ggatggctgt gaaagttgcc cagaagctcc caaccgttgt ttctcatatc tttgactgcc 26461 gcaaactgct cctttgggtt catggagaaa tgttccgggc tttcgtctat gttcctcaac 26521 agatacactt tctcaacata tttcacacca ttctctatcc tgccgcccaa aagcccgcag 26581 gcttcattgg gcaaagcatt gcgggaatgt tcaagtatct cttggtactg ctgctttgtc 26641 atgacaatca caatcggcca cctccaatac ccaatcagga tttcaaatcg cacactgcct 26701 gttcatagtc tataagctct tttatggtag gattttcacc gcaaacctga caccttttgt 26761 tccacggcaa tttaactttt ctaaactcca tcgcttttgc gtcataagtt aaaatatagc 26821 ctgtaagcag ttcaccaatg ccaagcaaat atttgatagc ttctgttgcc tgaatagttc 26881 cgataactcc gcccattacg cccagcacac cggcctgttt gcatgtggga actttatccg 26941 gtggtggggg attctcgaat atgcacctat agcacggccc tttacccgga acataggtca 27001 tggtctgacc ctggaacctt ataattcctg catgggaaaa gggttttccc gtaagaacac 27061 aggcatcatt tattaaaaac tttgccggga aattgtcggt gccgtctata ataaaatcat 27121 aatccctgtc cttgataata tcttttatgt tggctgaact tacccactcc tgatatgtaa 27181 caacattcac atcgggattc atttcattga tggtttcctt tcccgatata actttgggtt 27241 ttcccacatc tttggtaagg tgaataatct gtctttgaag atttgaaagc tccaccgcgt 27301 caaaatccac aagacctatt gtgccgaccc cagcagcggc cagaaacatg gcggcgggcg 27361 ctccaaggcc gcccgttcct ataatcagaa ccttcgactc cagaagcttt ttttgccctt 27421 ttaccccaac atcttttaaa attatatgtc tggaatacct ctccatctgc tcattggtaa 27481 aattcatatc gcgccgcctc ccataaaata aaggaattcc acgacgtcgc cctcttttac 27541 cgtcaaggtt tcaaaatcct ttctgtccaa aatcttgtca tttatctgta ctgtgacgta 27601 atccggcatt tccacctttt gaatctccag aagttccttt acggtaacct ctttttcaag 27661 tgttacgtcc ttgccattta ccttaattgt catttacaac cccccatatc ctcatatata 27721 atattcaagt ataatttcct gacgtttcaa caactcacac acagcctcaa cagcgccctc 27781 cgtatcttct atgtttgcat cgggcacaaa attgttgaaa ggcgtctgtc ctatgtttac 27841 cactatgatt tcattgggct ggtttaaaag tttaagcttt ttggcctcat agtcatccag 27901 attgaatatg ctggtgataa atatttggcc cgaatcggta aatatccttg ccagttctcc 27961 aatctgcctt atatgctcgt ctctgtcctc atagctgttt gccacatccg acgcaagccc 28021 gtgcagtatg cttgaaacac cgagataata cgctttgtac ttcatgttga aaagccgctc 28081 ttccaattgt cttccgatat cctggatatc cttttctttt ccttcgcttc ccgaagtaat 28141 tacgataaac ttcgctttgt gtccataagc attttccctt tgctttgcag aaatcaaact 28201 tttttcccac aaaaattctc tttccctgat gtgggtcagc aagctgctgt cggtatccgg 28261 aactgcttcc aaaataattc ctccgccgga tatctcatag ttgtccacaa ttacaaacct 28321 tccggtctgc tcgatttcgg aaataacatc atatgcaata ggttttgcgg tttcaaaaat 28381 gcactctgcc acatcatgtc tttcaacctg gtctttgaaa gtgtcaatgt tgagctccgc 28441 cgcatcaatg atatgggata tttcaatgag tttgacgcca attttcatcg taccgatttt 28501 caacttatag tttttgttct ttatcaaagg agccttgcca acccagaata tgttcgccct 28561 aaagcgggag ctcactgacg gatgtttttc atttgccttc accatcagtt ctccgggctt 28621 tatataaatt tgtgtggtca gcgttactcc tattgcctcg tctgcatagg ccgtatttct 28681 gggttttaca ttaaatccct ctatactttt tattaccgac ttcttgtttg aaggaagaaa 28741 tacaacctcg tcccccacac tgattgagcc gcttatgatt gtacctgcca caatccttcg 28801 gtcatcgccc tcttcggtaa atttgtaaat atcctgtaca ggcatgcgga acggaagctg 28861 acgattttct tttttattca caaacccatc caactgttcc aaaaccgtgg gcccgtcata 28921 ccacaaagtg ttccgggacc tttgggcaat attgtctccg ttgaaggcac ttattggaat 28981 ataattaatt ggtcttatgt taaccttttg caaaaactcg ccaaactctg agacaatagc 29041 ttcataaact tccctgtcaa agcccaccaa atccattttg ttcaccaaaa caaccacttg 29101 tttgattccc agcatggaaa caatatgtcc gtggcgtttg gaattttcct ttataccttc 29161 cttcgcgtct attaccaaaa gggcggcttc cgcccgggac gctcccgtaa ccatgttctt 29221 taagaactca acatgccccg gtgcgtcgat aataatgtag tcccttttgt ttgtcttgaa 29281 aaaacatctt gcagtatcta tggtaatgcc ctgcgcctgt tcatccttta atgcgtccag 29341 caaaaacgcg tactcaaaag gtctggcatt ctttctgcaa aactctttga cagactcaag 29401 ctttccctcc ggaagagagc cggtatccgc aagcagtcta cctatgacgg tgctttttcc 29461 atgatccaca tgaccgacga ttacaatatt catttgttct cttgcttcca tatcacatgt 29521 accctcctct tctcaaggtc tcaagaccgc ccccgtcatc ctggtcctgt gcccgtccgg 29581 ctctttccgc tatgtttgca aacttgccgc tttttaactc ttcaataatt tcccttacat 29641 tctttgccgt cgattccaca ggaaaagtac atggatagca tccaagggat ctgtaacgct 29701 ttccgtctcc acggtcaaaa tacagtggtg taaccggtat gttttctctt tctatgtatt 29761 cccagatatt aagttccgtc cagtcaagca gtggatgtat tctaatatgg gttcccggtg 29821 caaagtcggt cttaaattga ttccaaaact ccggaggctg gtcttccaca gcccagtcgc 29881 tctccttgtc ccttggcgaa aaatatcttt cctttgaacg gcttccctct tcatcggctc 29941 ttacgcccac aataaccccg gtaaaccttt ctcttttggt gtccaaaaca tattttccgg 30001 tcttatggtc taaaatataa cggttccatt caccggaaag agtatgtttc aaagcttcgg 30061 tttttaaaag ctggcagcat gtcaggcggt ccacgtttcc gtcggggaaa gttttcttct 30121 gtgccaaggc ctcgctgttt tctccgtata tcatggtaag cttccatttt cgtgcaagtt 30181 catccctgta ttctatcatt tcaggtattt tataatgggt atcaatgtgt accaaaggta 30241 tcggtacatg cccgaagaaa gcttttctgg cgagccaaag aagtacagta ctatcctttc 30301 ctatggacca cagcatgcat atatttttaa actctctgta agcttctctt aatatgtaaa 30361 tactttgtgc ctccaatttg tccaaatgat ccataccgtt ccccccatct tgtgtacaag 30421 ctgaattact tttgtcatca tatgtcctct cacatactct atatttaaga cccatcctat 30481 tcttgtgtgc aatcagcatt cttttttagc aacgtacgtc caatcacacg ctctacaacc 30541 aagaacttac ctgtttttgt gtgtaatttg cattttttgt cagtgtacgt ccaatcacat 30601 gttccataac tcaaacctta cctgtttttt gcgtacaatc cgtatttttt gtcagtgtac 30661 acccaatcac acgctccata tttacacctg tcccactctt gcgtgcagcc cgcactcttt 30721 tttgtcaggg tcttcccacc accatctgcc gctgcgaaca tcctcgccgg gtcttaccgc 30781 cctggtgcat ggttggcatc caatgctccg aaaacccttg ctgtacaggg aattgtacgg 30841 aatattatat tttttaatgt attcccacac cctatcttca gaccagaaaa caatgggatt 30901 tattttataa attgaatgaa ggccgtccca ttcaaaaata ttcaattcct ggcgcgtcaa 30961 cgattgttct ctccttaagc cgcaaatcca ggcatccaca gtgctcagga ccctttttag 31021 cggatttacc tttcttattt cacagcactt tttcctaagt tcaacgcttt cgtaaaagaa 31081 attgggaccg tacttcgaaa cggcctgctc cagttctttg ctttccggag cataaacttc 31141 gtagtggaaa ccgtatctgt gcatggtttc ttccataagg tcataggttt gctgaaaatg 31201 tcttccagta tcaaggaaaa acacccttgc ttttggattg attttaagca atatatccgt 31261 cagcacttga tcttcaattg aaagacttga agccaatgca actttctcaa tacctatgtt 31321 ttcaacaaca aacctcacaa tatcttcagg acttttatca gaatattctt tgtttaattt 31381 ctccaaatcc aactgcacca tcttttcttc ccctttgcat gcatttgcaa tatattcatt 31441 tacacatatt tgtgctaaat tgcacaatct aaattacata atcctcggga ataaaaactt 31501 tgaaatcttt tggccttaca taaacagtct gcctttcctt aagcccaagt tttctgtatg 31561 tttccttgct aatctcggct tcaatatatt gcccgttgtc cagtctcacc agttcaatct 31621 tgacaatggg tccgaccgcc cttataaaag taatccggga gccgataaat tcctttcctt 31681 ccggttcaag cttaatctca atatcatggg ggcgggtgta gcttactata tctttaccct 31741 gaccgccgtc cgaatctgcg ccgggtaagc ccagttcaac ttttccgtta tgtattcttc 31801 cgtgaaacag gttcacattg cccagaaagt tgtatacaaa aggatttgcc ggattgtcat 31861 acacttcttc cggtgtgcct atttgctcga tttttccctg atttaaaatt acaaccctgt 31921 cggccacatc cagtgcctct tcctggtcat gggttacaaa cacgctggtg atgggatatt 31981 cgtcgtgtaa cttcctcagc caccttctca aatcttttct tactttagca tccagtgccc 32041 caaaaggttc atccagaagc aagaccttcg gctccaccgc caatgccctt gccagggcaa 32101 ttctctggcg ctgtcctccc gacagctgcg aaggataacg gtttgccagc tcttccatct 32161 ttacaagctt caacagttca tataccttat tctttatagc ttccttgttg ggtcttattt 32221 ttgaaggcat aactctaagg ccaaatgcaa tattttcaaa aaccgtcatg tgtttaaaca 32281 atgcataatg ctgaaacaca aaccctactt ttctgtcctg ggcactcttt tttgtattat 32341 cctctccgtc aaaaatgatg cttccttcat ccgctgtctc gaggcctgca ataattctca 32401 aaagtgttgt tttgcccgaa ccggacggtc ccagcaaggc aaccagttcc cccgtattaa 32461 tgtgcaggtt gatattgctc agggccttaa atgaatcaaa ggtttttgat acgttgcgta 32521 tctcaatact cataactaac caatcccccc agatttatca caacgtcaga agtccctata 32581 ttttgctttg ctgctgtatc ttccaatggg ctacgttctt tacaatcaaa tttatcaagg 32641 caatgagggt cagcagcgat gccactgcaa atgcggcaga aaatttatat tcgttgtaca 32701 atatttcaac atgaagagga accgtattgg taagacctct gatatgccct gatacaacgg 32761 aaaccgcacc aaactctccg gccgcccttg cagttgtcag cataacgccg tacagcagcg 32821 cccattttat attggggagc gtaatgtacc aaaaggtttt ccagccgctt gcccccaggg 32881 tcagcgcagc ttcttcctct gcagttccct gggcttccat caagggtatc agctcccttg 32941 ccacaaatgg gagagtaaca aacaatgttg caataacaat tcccggcggg gcaaagataa 33001 tttttattcc caaagcatta agcagcggtc ccaaaagtcc gtgactggtg ctaaagagca 33061 aaacaaatat caatcccgcc accaccggcg atatggaaaa aggcaaatca ataatcgtaa 33121 tcaatatgtt ttttccttta aacttaaatt ttgcaatcgc ccaggcagct gcaaggccaa 33181 atatggtgtt aatcggaacc gtgattgcta tggttatgag ggtaagtttt atggccttta 33241 gtgctatcgg atcggtaatt gaagcaaaat acaaattcgc tccctgttca aaagctttta 33301 cgaacaccga aacaagtgga actatgagca ttattataaa aaatagtatc gctattgtcg 33361 ttaaaaccac ctgaacaatt tttgagtctt ttaccgcccg cttttttgca tattccactt 33421 tatttgccgt ttttattctc acaggaacaa tccccgccat ccaaatcact cccagtttgc 33481 catatgtctg tcagttgccg ccaaatactc ctgcaactct ttacattcca tactcacttt 33541 agatacttac cttgatctgt gtctgcctgc ccaccactgg aatgcgttaa tcatcagcaa 33601 caggataaag gaaataacca gcatgactgc ggccaccgca gtacctcctg cataatcata 33661 ctgttccagt tttgttctta tcaaaagcgg tgttatttcc gttttcatcg gcatgtttcc 33721 ggatataaaa accactgaac catattcgcc cagggccctt gagaacgcaa gggcaaaacc 33781 tgttatcaac gccggaaaca attccggcag aataactctg caaaaagttt gaaatctggt 33841 ggctccaagg catgccgccg cttcctccac ttcaacatca aaactttcca gcactggttg 33901 tacagtcctt actacaaagg ggaatcctat gaaaaccaag gcaacaacta tacccagggg 33961 agtatatgat attttgattc caaacggcgc gaaaagcctt ccaatccaac cattctggga 34021 atataaagtt gtgagcgaaa tacctgcaac agcggtgggc agggcaaaag gcaagtcaat 34081 taagccatcc accagttttt tgccccaaaa atcgtacctt tccaaaaccc atgcaagaag 34141 gagcccgaaa acaacgttta ttgccgcagc caaaaaggat gtaccaaagg atatcttgag 34201 cgaagccagc actctttccg aagaaacaat ttcccaaaat ttatcgaggc ctatttgggc 34261 actgtttagg aaaaccattg acacagggat taaaaccagc aaagtaagat atgtaagagt 34321 aaatcccatt gtaattccaa aacccggtat gacgcttttt tgttttaatt taaacggctt 34381 gattccaaga ttcatgactc cactcccaag acttaaagat tatttcttct catatatttg 34441 gtcaaagata ccgccgtcat caaaatgttc cttttgcgct ttatcccatc cgccaaagac 34501 ttcatcaatg gtaaaaagtt caacttcggc aaattgcgaa gcatattttt gcttgatttc 34561 ttcttttctg ggcctgtaat agtttttagc cgctatttcc tgcccctcgt cactgtacag 34621 gtattcaaga taagcttccg ccacctcacg ggttcctttc ttgtcaacca ccgaatcaac 34681 aacagcaaca ggaggctcag ccagtatgct cacagacggt acaacaattt cgaatttgtc 34741 tttgcccagc tcattcaagg aaagaaatgc ttcattctcc caggctataa gcacatctcc 34801 caatccccgc tccacaaagg tcgtggtaga gccccttgct ccggaatcaa gaacgggtac 34861 gttggcatat attgctttaa caaattcctt ggctttttcc gggtcattgc cgtatttttt 34921 cagggcatat ccccatgccg caagataatt ccagcgtgca cctcctgaag tcttggggtt 34981 tggagtgata acttccaccc ccggtctggc aaggtcatcc cagtccttaa tatttttggg 35041 gttacccttt cttaccagaa atacaatggt cgaagtatat ggagttgaat tgtacggcaa 35101 gcgtttctgc cagtctttgc tcaaaatctc tttgtttttg tttattgaat caatatcata 35161 cgccaaagcc agggttacga catcagcctc aagaccgtca attacagctc ttgcctggct 35221 gcctgagcct ccatgggact gctggatgac aatgtccttt ccggtttttt ctttccagta 35281 ttttctgaat gcttcattgt aatcctgata aagctcacgg gtagggtcat aggatacatt 35341 aagaatcgta acaggttctg tttgaccgga atcgctttga ttattgcctg cttcttttgc 35401 gcatcctgca aaggagacaa ggccggctat aatcagcagt actgccaggc ttgacttgag 35461 aatatttttt cttcccttat ttttctccat aatcatctct cctcacaaaa tactaaatat 35521 aagtattcat agcaatttag tgtgttttaa gttaaaattt aaagggtcat cccctttaat 35581 ttatatcaca ctattcatat atgaattatt gtgtttattt tactaccatt tttatctact 35641 gtcaatagat tgagaaaaaa ttttttatta ttcctatata aatactctgg attatattga 35701 gaatatattt aaaatttatt tgaaagtatt ggaaagcaag cttataaaac ctgccaatgc 35761 aacaccgcta aagctctgca cggtgtttac acgtctactt atgccggggg tgacttgcgg 35821 gcaaaaaaca aacttacctt ctccaatgtt tcatcaatat ctttgtctgt atgggcgttg 35881 gaaacaaaca tcgcctcaaa ctgagatgga gcaatatata tgccgttgtt caaaagatga 35941 ttaaaatatc ttccaaacag tccggtatcg ctttttaccg cactgtcata gtcatttact 36001 tcctcctcgg tcataaacac gcagaccaaa gagccgacgg cctttacggt atatttggtg 36061 attttcccaa gcccttcgct taatctttga ccaagcctgt tgatattttc aaaaattccg 36121 ggattctcat aaagctccct caatgtggca attcccgccg acatggcaat gggatttccc 36181 gacaatgtcc ctgcctgata tacatctccc accggcgcca cacattccat gatttctctc 36241 cttcctccat aagcgcccac gggcattccc ccgccgatga tttttccata ggtcacaaga 36301 tccgcgttaa cgccaaaata ttgctgtgcg ccgccaatag ccagcctgaa tccggttatt 36361 acctcgtcaa aaatcagcaa agcctcttcc ttgtcacaca gttttcgcag ctcttcaagg 36421 aaattgtctt tcggaggaac gactcccata ttggccgcca caggctcaac tataacagcc 36481 gctatattgc ccttgttctg ttcgaacaaa agcttcacac tgtcaatatc attatacctt 36541 gctatcagcg tatcctttgc ggcacctgcc gttacacccc cactattggg gattccgttt 36601 gtcatcgcac ccgagccgac tttgaccagc atgctgtccg catgtccgtg atagcagcct 36661 gcaaacttta taattttttc cctttttgta taaccccgtg caacacgaat tgcactcatc 36721 accgcttcgg taccgctgtt taccattctg accatttcaa cggagggtac aagttctgta 36781 ataagctcgg ccatttgaac ttccaattcc gttgcggcgc caaagctcaa accgtccacc 36841 attgtttttg ataccgcttc aagcactctc gggtgggaat ggcccagaat catcggcccc 36901 cacgaaccca catagtcaat gtattcattg ccgtcagcat cataaattct tgcgcccttt 36961 gcctttttta taaaaggcgg ataacctccc acggcaccaa aagcccggac aggactgttt 37021 accccgccgg gaatcacttt tttcgccctt tcaaataaaa gcttcgattt tgataacgtc 37081 attatcctat gtcccccctg ttaattgctt ctgctatctc tttggcgtag tatgagatta 37141 aaatatccgc tccggctcta aagatagata ctgcagtttc gcacatcgtt gggtattcat 37201 ctatcagatt cattttcgca gctgctttta tcattgcata ctctccgctg acactgtatg 37261 ccgccgtggg caggctggag tgtttggaaa cttcgctgat aacgtccaaa taagccaatg 37321 ccggttttac cattagaata tccgcacctt cgtttatatc cgtcaaggct tcctttacag 37381 cctctttttt gttgtgatag tccatttggt atgacttccg gtccccaaag gacggggcgg 37441 actttgcagc atcacggaac ggtccgtaaa aagatgacga atattttacg gcatatgaca 37501 tgataagcgt attgataaag ttgtgtttgt ccaactcttg ccggattgcc gccaccctgc 37561 cgtccatcat atccgacggt gccaccatgt ccgccccggc cgctgcatgg gacagggcaa 37621 ttttggcgag atactccaga gttttgtcat tgtcaacata tccatggttc aatattccgc 37681 aatgtccgtg ggaagtatat tcacacatgc agacatcggt tatgacaagc acttcatccc 37741 tgtagcgctc cttaattgcc cggactgctt tttgtatgac tccgttttcg ttaaaactct 37801 ggcttccgat ctcatccttt tctgacggca acccaaaaag caaaaacttg tttactccgc 37861 attttagagc atcgtccact gcttcaaaaa ctgtatccgg gctgtaataa aaatggcctt 37921 caagagagtt tacaggcagc tttacatttt tgccctccat aaggaaaagc ggcaatatga 37981 gcgacttact gcttagcctt acttctcttg ccatatctct tatatgttga ttgagccgca 38041 atctgcgtgg cctgattagc ataatacatc accgccgttt ttaaattttt aatctttgtt 38101 tttgaaatct ttatttcaca attctttggt ttacaaattt ttgctttgca aatccttact 38161 ttgcaaatcc ttacattaca aatctttact ttagaaattc ttgtttccta aaattctcgt 38221 tttccggtga agaaaaatgt tccagaaact tgagtttctt ccatattttt cttcacctcc 38281 gttagcaggc ttattcagag taatgaaaat taggacgatg caaaataagt ttatttagcg 38341 caatgcattt caataatttt ttcaaccatt gaagaaaccg ttgcaacatc ggaaataatt 38401 gtgttcattc cataagccct tgtagctttg gctgtttgtt ctccaatgca tattgcattg 38461 atttttgaat aatctattgt gtttttaaag gagtgggcaa agccttttac gcagctttcg 38521 ctggtaaaag taatataatt aaaaccactt atgtcaattc tctcattttc tatgcattta 38581 gtttcatata cagagatatc agtgtagtgt atattattgt tttcgaaaat atctacaatg 38641 gcctgggttc cgtcctttgc cctgaaaata accactttgt cttcagggct tattttgccg 38701 ctttgcaaaa gctcttccgc taaatgtctg ccgtcaaatt taccgggaac aaagtcggcg 38761 catattccgt gttttaacag ttcttcggcg gtctgggagc ctaccgctgc aattttttta 38821 ttgtacaaat atctgctgtc aagcttgttt tcatacagtt ttttaaagaa tattgttaca 38881 cccaggctgc ttgtgaaaat tatccagcta tgctctcgta tatcaatgtc aaagtcgagt 38941 ggttctgttt ctatgcaagg atattcaact acatgtgctc cgagccctcg gagtttgcct 39001 gccaatctct ccgatgtttt ctttgggcct gttaccaata cattgcatcc gtaaagaggc 39061 aattttgaaa accaatcaag cttttcagaa agggaacata cctttccgac tatgattatt 39121 gcaggggatt taacctgatt ttctgcgata actttcggga tgtcacaaag ctttgaaaca 39181 aattttcttt ggtttggcat tgtgccgttt tctatcactg ccgcatccat atcggattcc 39241 atgccggctt ctataaggcc ctgtgctatt tgcggaaatg aggccaccga catcataaag 39301 atgagagttc cttttagctt cactaaagat tcatagtcga tgtccggatt tccgccgtct 39361 tttacatgtc cggttataat atgcagcgac gagcaaaaat ctctatgggt gacaggaatg 39421 cctgcatatg ctgctgcggc tattgccgaa gtaatgcccg gcactacctc aaaaggtatg 39481 ccgttttgat gcaagaactc cagctcctct ccccctctgc caaatacaaa gggatcgccg 39541 cctttaagcc taacaacaat tttagcttcc agtgctttgg ccagaaggat tttatttatt 39601 tcatgctgag gaaccggatg attgccggca ttttttccaa catagatttt ctccgcattg 39661 tcgggaattt ttgaaagaat accatcgctt ataagtctgt cataaactat gacatccgcc 39721 ttttttataa catcggctgc cttaacagta agaagttcct catctcccgg tcccgctccc 39781 accaggtaaa cctttccttt gccgtcagcc attatgcatc cgctcccttc agcatttcca 39841 tcgccaaact gtatcccaac gcttctccct gatttctgtc tcccgttttg gtcattttat 39901 aaattttgcc gtttttatca acataaaatc ccgtgagaac tattttttcg ccctgtatca 39961 ctccataagc tgcggacgga gagctgcatc cgccgttcaa tgcctttata aagcttctct 40021 ccgccaccga cacatcccac gagtctttgt catggaaatt tgccaaaatc gatgcgtcaa 40081 aatcttttcg tgcttgtaca gctataattc cctgacatgc cgccggaaca atttcatccg 40141 tactgaacac acgccatatt ctctcttcaa gtcccagtct cttaaggccg gcatatgcca 40201 gggctatggc tgaatattct cccttgtcca gcttttcaag gcgggttaaa acatttcccc 40261 ttatcggctc gactgtgcag ccgggataga ttttctctat ctgaattttt cttcttgaac 40321 ttgaacagcc gatgggaccg ttaaaatcaa tttcattttt ccctttgggc aatacaagca 40381 catccctggg gtcttccctt tttgaaaccg caacaatggg tagacggtca tctatatcca 40441 tgggcatgtc cttaaagctg tgaacggtga tatccacctt tccgtccagc aaggcacgat 40501 caagttcctt tacaaacaga cctttcccgc caatcttgtc aatggttttg tcaagaattt 40561 tatcccctgt tgttttcatt gtcacaagct cgatctcgat atcggggttg tattttttta 40621 tagaatctat cactatctgc gcttgcctca cagcaagttt gctttcacgg ctgcccactc 40681 tgattttcat gtttcaatac cttccttatc ttatttgata tttctttcac ctttttatga 40741 gattttccgt cgccggtaac accgacaaca atttcgtctt ttacgatgac ggccggaaaa 40801 taaaaattgc attcttcttt cacatcagcc acactcacat aggctcctag ttcttttgcc 40861 ttctccccta tatatttgtt tatttctctt ttgtccgtgg ccgcaacaac gagaaatttg 40921 ccgtccaaat cctcatttct aaattcgcgc tgaatatgcg taacaagccc gtcatccgca 40981 agttgctgaa tttcatttgt tatgtttggc gccacaaccg ttatctcaaa ttcaaagttg 41041 gtaagcgtca agatccttct tgttgcaatc ttacctccgc cgaccaccag cactttttta 41101 cctcttgaag aaataaacaa cggaaaatgt tctttcatgt caaaaccagc cttttcctat 41161 attcatacca tctatagtaa tcaaaaatgt atttgtcaat tatctttttt acctgtatca 41221 tctgctctgt acggttttta tccacttcac cggcatagat actgtcaagg tcatacagct 41281 ccacattgtc caaagatttt attttggggt caatatccct tggaactgca aggtcaatga 41341 ataaacgagg atattttatt ctgtcgattt tgtctatttc caaagtataa tgcgggctta 41401 gagtggcgct gattacaaca tcgcaatctt tgagcttttc atacctggcg acgtactcta 41461 tggtttttgc ccccaggggt ataatattat caccgtggcg atagcgtctt aatgttattg 41521 tggtgtcata tccgttttca atcaatattg acgccataag cctgccgatt tccccgtttc 41581 caataacaag ggccttgctt atattctcct tgctttttat aatctttaaa gcactgtaag 41641 ctatggatct ttccgtgctg ctaagtttca gtgtggtttt cacttttttg gccgatgtta 41701 cggcaattct gaacattacc tccaaggtac tgtcactggc attcatttcc cttgccagtt 41761 caatagcgtt tctgacctgg gtaatgattt ggtcctcacc ccatatttgg gactttaccc 41821 cgcaggcaag ttcgcacaga tgcctgatga catcaacacc cgttctcaat acatgcatat 41881 tactgtactc ttcatagtcg aaatttgcag cgtcgcataa aagctcaaaa gggtttatat 41941 acaatccttc ctcgcatgaa aggtacagct ccgttctgtt gcatgttgaa acaatcacag 42001 cgccgaaaat gttttcattc tttagcaagt cattgtatac agcttgtaaa gtggactttg 42061 taaaagaaaa cttttctctg atatcgatcg gtgccagggt ataatcaatt ccggccatga 42121 ttacattcaa aatccgcacc cccgttcttt ctctactggg aatattttgt tgttatatta 42181 ttgttcctat atgtttactt ggattttgta tataaatatt aattaaaaag catacaaaca 42241 cgttctctaa gatatacaaa tgcttattcc aataattggc tgtttattat tttaaaaaac 42301 tatttaccgt tttagcctgc aaaacaccta taaaagaaat gtttcgaacc ctttggatgt 42361 taaatataat acataacaga agaattgtct tccaactttt gatattctct cagcaaatcc 42421 ccaagggtaa tattgtcaac aactttgtca atactcttgt taattttgtt ccagacaaat 42481 tcgtttatac acttctcttc tttgctaacc tcactatccc tgtcatctat gtctacaaca 42541 ttgaggtttc cttctaacgt gcgtaaaatt ttgccgactg ttatattgga agggtcgtct 42601 gcaagaacat atcctccctg cgcgcctttt atgcttttta ctattgcggc ttttcttaat 42661 atggaaaaga cctgctccag gtatgattcg gaaatgttct gcctttcggc aatgctcttc 42721 acgcttacta tatcaccttt tgaattaaca gcaatatcca gcatcgcccg caagccatac 42781 cttccttttg ttgacatctt cataaatttg caccacctca atacataagt aaacctattg 42841 ttttagttag ttattttata atataacaat ttataaaatt tgtcaataag attttttata 42901 atttttccat catattcaaa tgtgtcggat aatttatgga atattcgcaa gaaatggcgc 42961 gtaataaaat ctcgaaagga attgaataaa catatataaa ccaagcactt tatctgatag 43021 agcacttggt ttaatttaaa gtgatgagac ttaattaaag tacttaaaaa tattattcaa 43081 aatcttttaa ctgaatattt aaagcattaa tcgaaatttg cagttcatac accagcaatc 43141 ccaacgaaat caacaaaagc aacaaactga ttccaaaaac aatatccgcc aaaaacatga 43201 ctttgaaaaa aatcagaaac atgcatgtaa cgcaaaagaa aaagcttaaa gccccaaata 43261 tctgcatatt tttgataatc acaattcttc tttttaaatt gtacaactga ccctttgtga 43321 cttcatccgg attttccttg tatttggcat atagttcgcg gattaactga gccagcacaa 43381 caaaacgatt tgtatatgca agcatcagca aggaaatagc cgggaaaagc aacgccggtg 43441 ttgtaagctc catataatca ttcccttcac aaattccata tgaatatatc caaatgatat 43501 atatccaaat tagcagtata taaacataaa acaaaatact tttccggatt aatcttcttc 43561 gtattatata aacattgccg gttttaatta agtttcacag ataaacttaa ttaaaaaccg 43621 gcaacggtta ttgtcgcttg gattttttag tatcttttct tcaaaatttc ttttcccggc 43681 tccggaggtc tgtccggttt attctccttt tctgcctctt tgggtttttc aattttattt 43741 tcctggtatg gatttttcat cttttccgta tttttcattt cttccatctt tttaacccac 43801 tcatcatgct gctttttttg ctcctcctgc atctttttca gccattcatc gtactgtttc 43861 ttttgttctt cctgcatctt tttaaaccat tcatcatttt gctttgtcat atcctctttt 43921 tctttcggat ttccccaata tggattccaa tagggattcc agtaagggtt ccaatatgga 43981 ttgtattggg ggcagctgcc attgttaatg tttttgttgt cttcattatt cattttatct 44041 ttgctatcaa catgcttgtt atctttgtcg tctttgctgc cgccgctgct aaatttatta 44101 tccggattaa tcggagtaat tttattgtct ctgttgatgt tattgttgat tttagcattg 44161 ccgtcagctt tatcattttt gttgtctttg ctgacatcgt tgaaggtttt ggcatcactg 44221 ttggttttat tatctttgtt gtcctttttg acgtcgttat taattttagt attactgttg 44281 ggtttactgt ctttgttgcc cttgtcaatg ccgctgtcaa tcttcgcatt gctgactgtt 44341 ttattctctt tgttatttat gtcggtacca acattgggtt tagcattatc ggttttattc 44401 accggtttga tgcctgcatc cggaccggcg gtattttctt ttaccccggc acttgtttcc 44461 acatcggctt ttctgtcagg taatggctta ttcggctcat tgtttacctt tttatcgtca 44521 tcctttcggt tgttctcatt tggaactttc tttatgtccc tgatggtttt tacaatctca 44581 ttcacaggtt tgtccttgta ctcttcggta gttgccttgg gatcgacttc tttaagcttt 44641 tcaatcaaaa gcaatttgcc cggagatata ccaagttctc tggcttcttc gcgtctttcc 44701 agcactatgt tctcaacaat cacctcggaa accacgttat catcatttaa aaccttgttt 44761 gctgtactct ccacttcttc ctttatttca agaacttttc tggaattctt gcctgcaacg 44821 gtaagcatga tggtattttc ttcatcattt ttaaggaaac cttgtgccac ggcactgtca 44881 ataatttttt ccacaccttc atccaaccgg gaattcttat aagaatcctc aatcagcatc 44941 tcgccttcag aatttaacgc ttttacatca ataatccggt tgtacatatt aaggattatc 45001 tccaaactgg gatttatgtc aacattcacg tagctgtaag gcaaattata gctgtatacg 45061 gcaaaggaga tacttgaaac aatcaacaga gctgctgcca cagatactac tttcaataac 45121 gttcttcttt caaatccaat cactctgtcc ggcaattcaa cttgatagcc caatctatgc 45181 tctgctttcc tcttaatctt aatgtattga ccctctttat taacaacaac agcgtatttg 45241 tcattcatat caactaccat tgccctcatt attccacctc ccagtttacg taatccctaa 45301 taaactcgta atctccggta aatattatca ctactgttat aatatatttt cgagcccgtt 45361 caattgtttt ccgaggtatt ttaaggctct gctctatctc tgcaacgggt aaatatttct 45421 tttgctttat tttctccata atatccggtc ttgaaaggac aaactttatt attttcgaat 45481 aaatcttttt ggtcctttta tgctttggtg atatgttaac caaatcaaaa aaagatatgt 45541 cccattcttt aagctctttt ttcaactgtt caagctcgag ccttctgtac tcgctgattt 45601 cttcttccga gtacttatca atggacatgg caatgccaag gtcggtctcc tcttcttcgt 45661 cttcgaggtg cccgtttata ttaacaacca cgctgtgttt cttttctttt ctgtaataat 45721 ctataattct tcttttaata acattctggg agaaggaaag gaaattgcct tttgagacgt 45781 cataagaacg gatagcctcc acaaaagcca tcagagcaat gctaagttca tcatcctgtc 45841 cgtaggcaac atagcgtcca accaccttct gcgtgcaggc tgctatgaat ggtttatact 45901 cttctacaaa aagatttatt tcctcttcgt tgttttttat tgcctcaact ctttggttta 45961 tagtaacaga atacatttgg ttgcctccaa caataaataa aatttgatgc agtcatgtca 46021 cccagttgca tcagcaaagt tcgacacaaa tttaaataac atcagtcgaa ttttggctga 46081 taccattttc taatgttact ataaaccata ttaagaccaa aatgaagtaa ttttttgtaa 46141 aattattaga tttaacaaaa atgtaattat tctactccat tctaagttca aatctgtcga 46201 acttcacatc ttcaataaac tgatccctgt caaaaaaggt tttacggtat ctggcaaact 46261 cggaggtgtt tttgttcagc caaaggggaa cggggatatc cagctccctg caaaggctaa 46321 tgagaccttc ctccagcaaa tccctgaaat cggtatcttc agcctcttta ttaaaaacag 46381 actcttttat tgcatgtgtt ccttttatca gtctgccaac aagtatcaac tttctcgcct 46441 cattctatca attttcccgt tccccggctt aagacttttg ttttgcttcc ttgtccttga 46501 taagcttgta ttctatagaa tccaccaacg ccttccagct ggcttcaata atgtccgttg 46561 aaactccaat ggttgtccag acttctttac cgtcggttga ctcaattaaa acccttacct 46621 ttgcagccgt agccgagttg gaatcaagaa ccctaacttt gtagtcggta agcttcattt 46681 ccgcaatctg aggataaaat ttctccaaag cctttcttag cgccttgtcc agcgcattta 46741 ccggaccctg tccctcatcc gcggttatct catactgtcc gtccacatta atctttatca 46801 tggcggaaga attcgcaccg ctaatagacg gttcgttaac cacaacctta aactctccaa 46861 gttcaaagga aggacggtat tttccaagga ttttccgaat cacaatttca aaagaactct 46921 ccgcaccttc gtactgatag ccttcaaatt ccagctcctt gagcttgtcc agtatcaatt 46981 ttgtctcggg agaatccttt gtaatagtgc tgtcaatatt tttgattaaa tgaagcacag 47041 cgcttcttcc cgcaacttcc gacatgagaa aaagcctttc gtttccgaca acttcagggt 47101 tgatgtgttc gtaagctatg gagtttttgg ttaccgcatc cgcatgcatt cccgccttgt 47161 gggcaaatgc atatttccct acatacggag ccctttcatc atgtataaca ttggcaattt 47221 cacttatgga ccttgcagta gccgtaaggt ccgccatgtt ttcctgcggt atgcaatcat 47281 agcctgcttt aagctgcaaa ttgggtatta ttgtgcagag attggcatta ccgcttctct 47341 ctccaaaccc gttcattgtc ccctgaacct gcacggcacc ggccagcacc gccataatgg 47401 agttggcaac cgccatgccc gtgtcattgt ggcaatgaat accgacattc acgttaaact 47461 cgctcacaac cctggcggta atatccttga tttcattcgg gaatgttcct ccattggtat 47521 cgcaaaggca aatacagtcc gctccggcct caacagcagt tttgagggtt ttcattgcat 47581 aatccgggtt ggccttgtat ccgtcaaaga aatgctcagc atcaaaaacc acttctttat 47641 ttttgttctt aaagaaggat atggtgtcaa aaatcattct caaattttca tccagtgttg 47701 tctttaaaat atcggtaaca tgaaagtccc agcttttgcc gaatatggcc acagccggag 47761 tgtccgcctt taaaagcgat tttacattgg catcctcctg aacacttaca ttgactcttc 47821 tggtacttcc aaaggcgatt atttttgcat gccttaactt gacccgccct attctgtcaa 47881 aaaactccaa atcctttggg ttggagcccg ggttacctgc ttcaatatag cttataccga 47941 gccggtcaag tctctccaca attttcagtt tatcttcaac actgaacgaa ataccctgtg 48001 cctgggcacc atcccttaag gtagagtcat atatcaaaat cttcttcatc ttttcatcct 48061 tcctgaaaaa atgctttaca attcccaacc ttcctcaaaa gggaaggtcg ggaatcagcc 48121 ttttaatctg tttatttctt aagccagctc atcatctttc ttaattccgc gccgactttc 48181 tccagctggt gttctgcttc atttcttctc atggcaagga actgtgccct tcctcccgcc 48241 ttgttctcag ttatccattt tgaagcaaaa actccgtcct ggatgtcttt caatacagcc 48301 ttcatagctt ttcttgtttc ttcggtaatt atcttctttc ctgttatgta gtcaccatat 48361 tctgccgtat cacttatgga gtatctcatg tatgagaatc cgccctggtt tataaggtct 48421 acaatgagct tcatttcgtg aatacattca aaataagcta tttcaggctg atatccggct 48481 tcaaccagag tctcaaatcc ggccttcata agttcggtta ctcctccgca caatacggcc 48541 tgttcaccga acaaatcggt ttctgtctct tctttgaagg tagtttcaag gattccggct 48601 cttcctgctc ctattcctgc cgcatatgca agagcataat cttttgcttt gccggaagca 48661 tcctggtaaa ccgcaatcag agacggaaca ccttttccct ccacatactg gcttcttacc 48721 gtatgtccgg gaccttttgg tgctatcatg ataacatcga cttccggtgg aggaacaatg 48781 gttttaaagt gaattgcaaa gccgtgggca aaagcaagaa catttccttc ctccaaattc 48841 ggcttgatgc tgttttcata gatatcctgc tgaagctggt caggaacaag catcattaca 48901 acatcggcca tctttgccgc aacatcagta ttttcaactc tcaggccatc ctcaacagcc 48961 ttctgtcttg attttgaacc ctcaggcaaa ccgacaacga catctattcc gctatccctc 49021 aggttttgag catgtgcgtg tccctggctt ccatagccta ttatcgccac agtttttcct 49081 ttaagcaagc caagattgca atcactgtca taataaatct ttgccattta aaaatcactc 49141 ctcatcacta ttcttatttt ttataacttt attgcctctt tcaatggcta tcgtgcctgt 49201 tctgacaatt tcttttatgc caaactgctt tagcatgtcc tccaaagcgg caactttgtc 49261 cacactgccg gatatttcaa tggtcagcgt ggtttttgac acgtcaacta tttttgccct 49321 gaatatctcg gcaatctgaa ctatctccga ccttgtggaa gcatttgccc caacctttat 49381 aagagcaagc tccctgctta ccgaatcgga ttcatcaagt tcttttatct ttataacatc 49441 aacaagcttg tttaactgtt tggtaacctg ttcaactatg tagtcgtcac cgtcgacaac 49501 aattgtcatt cttgaaatct caggattttc agtaacaccc actgcaaggc tgtcaatgtt 49561 aaatcccctc ctgctgaaca aaccggctat tctcgacagc actcccgcat ggttttcaac 49621 caggaccgat aaagtatgct tcgccatttt aaaacctccc aattctataa ttgaacactc 49681 atagtgttga ttcttccggg tcaattttgc actcgagaag gtaaggtttg tcgtccgaca 49741 gcatctcttt caacgcatct tccacctggg aatcgtcgtc tattctcctg cccttgaaac 49801 cataagcgtc aaacaacttt ataaagtcag gattgtcgtc caaaaatacc tggaaataac 49861 ggccgcagta ctttgtcttt tgcagctccc ttaccattcc cagccttgag ttgttgaata 49921 agattacttt cactcccagc ctgttttgct tgatggtgcc aagctcctgc atgttcatct 49981 ggaagctccc gtctcctccc acacatacca ctttgcggtc gggacagcca atttttgccc 50041 ccaccgcggc gggaagcccg tatcccatgg tacccagacc tccggacgtt ataaaggtcc 50101 ggggcttttt gacaccaaaa tagtttgcag cccatatctg gttctgtccc acttctgttg 50161 taattatatc atcatcaccc aaaagcccgg tcaaaacaga caacaaatat ttgggattca 50221 caaaacctat accgggcctt ggttcaggtt tttcggcatg tttttctctt tctttttgag 50281 ttgtctttat ccattcttcc gtatctccct tttgggaaat atctataagc tcttttaata 50341 cctgcttcac atctcctacc accggtattg aaacatcgat atttttgcct atctccgcag 50401 gatctatgtc aatatgaact atctgctttc tctttgcaac ctgctgggga ttgcttatag 50461 ccctgtccgc aaccctcgcg ccgatgataa tcaaaaggtc agcattgttt acggcataat 50521 tcgcaatata tactccgtga gtcccaagca ttcctaaatt gagctcataa tcatacggca 50581 cggacccgat acccatcaaa gttgtaacaa caggtatgcc gcactttcgg gaaagagtta 50641 aaagctcctc ggatgcattg gaattaatca ctcctccccc ggcgcaaata accggttttt 50701 ttgccttttc aatagcttga gcaatctttt ttatctgaag agaatggcct tttaaatttg 50761 gcttgtagcc ttttatatca acactttccg ggtactcaaa attaatctct tttgtctgca 50821 cgtctatggg tacgtcgata agaacagggc ccggccttcc ggtggatgct atgtaaaagg 50881 cttcctttaa aacccggggc aaatcctttg cgttttttac caaataatta tgcttgcaga 50941 aaggatccgt cgcgccggta atgtcagcct cctggaacac gtctcttcca atcagctccg 51001 aattaacctg cccggtgatg gccaccaacg gtattgagtc catgtatgcg tcagcaatgc 51061 ctgtaataag gttggttgct cccggtcctg atgtggcaac acacacacca acccttcccg 51121 ttgttctggc atatccgctg gcggcatggg cagctccctg ttcatgcctg gtgagtatat 51181 gccttatttt agattccatc agcgcatcat agaaaggaca aattgcagct cccggataac 51241 cgaaaacaac ttccacgcct tccaattcca aagctttcac aattgcctgc gcacctgaaa 51301 gtttcataat tgccaccctc ttataccgaa cctgtaaaaa tatcaaaatc cgccaaacaa 51361 atttatacag cgaccaaatt tataaaatta aaccccctca tctccgcaaa catgttctat 51421 tgtctgcagg gacgaaggga ttatgtccaa cgtggtacct ccctgtttca acataccttc 51481 agtatgccat cattgtgggt atacatcttt atataccctg tgagccctcc cgggcaatca 51541 gatacatctt tgttccatca cagcatgtat ccatatagag catataatta ttgataaata 51601 ttttatcaac gcccatacat aaaatcaaca cgttttttat caaataccaa acccattttt 51661 aacgtatttt atcttatgtg tcccggcact agtattggac tttgtcctgt tttcgctccc 51721 attctttaaa agcctcaagg caggcatccc tgtccgtctg caccaaactt actctctttt 51781 cgtcagtttc tccttttata acctcatata tataattgtc atcaaaacct attttcgccg 51841 catcttcccg cgtacagcca taatacacct tctttatctt tgcccagtga atggccgcaa 51901 agcacatcgg acacggctca caggaagaat acaattcaca atctcccagg tcaaaccgtg 51961 aaagtttttt tgccgccttt ctgattgcaa tcatctcggc atggtcagtc gggtcattat 52021 tctttatgac ctcgttatga gcccgtgcaa taatttcatt gtcttttact atcactgcgc 52081 caaagggacc tccatgattc tgtctcatcc ctgacacagc ttctttgaca gcctctttca 52141 taaaatcatc catagcattt tcccatcctg taaattccaa gtttttgtcc gtaaaaagtt 52201 ttccatactt aatattacca taattgcgtc caaatttgta tatcctcgtg tgctattttc 52261 tcatataaac tcatataaat cctattatat aaatcataaa tcctaaatca atattctgtt 52321 ttcgctttta ccctcaattt ttcctatgct gtagccatag caaaaggatt gatacatgcc 52381 ggacacaatc aattcccgca aatactccct ttccgcctcg tcaaggccca catccataac 52441 tttgataaaa tctttaattt tttcggttgc aattctgccc atggcttccc ttgttccggt 52501 aaactcgttt aggagtttgt ttctcccctg tttcaggtat gtttttatca tttttttgaa 52561 atcattttta tcttgtattt tcctttgtgt gtccatcatt ggctcctttc atgtaaaaaa 52621 tgttttacca atgtaagtct tcccattttc acatgaagga tataccaaaa aattatatat 52681 aaatcgggag cttcatattt cctaccttgt cacaagtccg tctttctctt ttgcggcaag 52741 cctgacttgg acggtctggg gtttgccgtt gctgatatgt ctgatggtca ccacatcccc 52801 cgggtttttt gaataaatga cgcatcttag ctgcatcatc gtgcttatct cctcgccgtc 52861 aatctgagtc atgatgcagc ccacccgtat tccactcttg taagccggtc cgttttcgtc 52921 cacatttgcc acataaaccc cgttttgcac tttgacattt ccgtcaaggt aaggaataat 52981 gtctttgtca tatgcaaaaa cccccaggta tggctcaata aactctcctg tagttgcaaa 53041 cttgttgatt atgggaattg ccacattaat gggtacggca aagcctattc cctccgcact 53101 ggccactttt accgtattaa ttcccaccac ttcacctttc aggttcaaaa gcggtccgcc 53161 gctgtttccg ggatttatgc tggcatcggt ttgaataagg ccttccatgt aatttgtgcc 53221 ctgttcggtg tcaacctcta tagttctgtt aagcgcactg ataatacccg atgtgaccgt 53281 tctctggaat tgaagtccaa gaggattgcc gatggcaatg gcaggctctc ctactttaag 53341 ttttgtggca tcacccagcg gtattgtagg aagtccttcc gcttctatct ttaccaccgc 53401 caaatccaat accgaatctg accagacagt cactccgtcc aggtttttcc cgtcgaccag 53461 cgaaacaaca atccttttgc tttttcctcc agccacatgg tgattggtaa gaatataacc 53521 atttggggtt actattactc ccgaacccac accccaccgt tcgacagcat tgggattgaa 53581 tattgagctg ctgtcaactt tgagtacgga aatgcctacc acagcttttg acgcattttc 53641 cgcaacactc tgtatggtat tttgtccgcc cgtattattg gattgttccg ccgaaatctg 53701 ctgcggactg ggcatttcaa tgcccgaacc cccctgaggc gtttggggag ctgtactgcg 53761 gtttcccgtt acaaaacctg taacagcaaa aatcaacaat attccaacac ccagagatgt 53821 aagaagtgaa gttaaaaaca tggtgaaaaa accgtttttc cttctgccat tgtcaaacat 53881 actaccatcc ttttagagtt tttatttcta gtattgcaac aaaactctaa aagaattcaa 53941 aaaaataaat ctttttttgg atatgcttta taagtcttcc tccaggcttc gtataatttt 54001 tttgacactc ttttcaaatt tgggccgagg aagcatcacc tgatgctgac agcccagaca 54061 ttttatcttg aaatcagcgc ccacccgggt tatttcccac tgtttgctgc cgcacggatg 54121 ctgttttttt agttccacta tttctcctat gcgatatcta tgctccatcc cttttcccct 54181 cctttcatcc aattatttca ttcaatttaa tatttttatt aaatacttta ttaaatactt 54241 tattaaatac cctcatatcc atctctaaac taatattttt atgctcatat tcatactact 54301 catatctaca ccacacatac ctttaattaa ttctttaatt aacattttta atactttaca 54361 tcccggaaat atcttaggaa agttctatat tttccctgtc aaattcttct tttattgctt 54421 tccttattct tctttccact tcccagtgcg cacccggaag tgttttggct gtaatcctga 54481 gagtaaaacc gcctcttgca agttccgtaa ttccaagtac cctggggttt tcaactatag 54541 tgtcaaattc ttccgaaaca cttctgcaaa ctttgtccgc cgcttcaaaa actttgttta 54601 catccaccct gtaaggcaaa ggaatgtcaa caacaacagt tttgttgccc cttgaatgat 54661 tcgttacttt ttttatctca ccattgggta taatgtgcaa atctcctttg gaatccctta 54721 tctttgttac cctaagctca atctcctcaa caactcccgt cctgtcttcc agcgttacca 54781 tatccccaac actgtactgg ttttcaaaaa caataaaagc accggatata acatccttaa 54841 tcaagctttg tgaggcaaaa cccacagcca ggcctcctat accggcagca gccaatactg 54901 actgcagatt cagtgcattt gtgagaagtg tcaaaattgc cacacccgaa agaatatata 54961 ccgtgtacct gaacacactc accaaaagcg tggacatggt gtcaattctc ttgtcatcca 55021 gcctgtgttt aaatgatttt tgcttttcca tggcttttct tatcatcttg cttccaaatt 55081 tcgacagcaa aacacttatg accaatactg caattatttt cactattaaa accaacgggt 55141 tgtacagtcc tcccagaatt atctttaaat tcccgggaat attcgttatc cattctataa 55201 tgtcaacaat gtcaagaatc attcccattc tcctttacac tcataataaa catatttttt 55261 atatattcta attaaatact ttggcaaatg caatgatgca tgcaaatgac aatatatttt 55321 agaatcagaa cattttgttt cgcattgcga cggttttcaa gaaaatatcc ggtacacttt 55381 tgtcaataca tgttaaacat tttttgggca tgttctcaaa atagaacact tttggacttg 55441 ttttgcaata tccataagat atataatata aacagaaatc caagggaaaa gtttttttcc 55501 ctctctaata ccagttcccg tagttatacg ggtttttttt tcagaaaaac acatccaacc 55561 acattcaaaa aagcagcaac ggaaatttta tccgaagctg cttctttctc tttttttctt 55621 atacgtgaat atataagttt catgtttcat aatcaatctt cctgaaatct tgacaaggat 55681 ttaatagcca taaatcccaa aataaatgta gctatggaca tcagtccaca accaatccac 55741 caaggtacac cggcgttttc aggaatggcg ggtagtattt tctcctgaaa aatttctgcc 55801 gtggaaccaa gcacaaaccc tataatcgca caataggtct gatgcggaaa ggtgtttaaa 55861 gtccattcaa tcggttttgt aatgagaaaa accccgatta atgtcgcaat tcccaatgtt 55921 ccgatataaa aaacatcaaa ctcggttatt gccgtaagca tagattcata catgccaagt 55981 accagcagca tatgggaagt actgataccc ggaagcacca aagccaaagc aattacaata 56041 ccggctacaa gtatcatcaa ataatggaca actcctgaac cggagccaat atttatgctt 56101 tcttccggaa taaatccaat ggatattaca acaagaagtc ccagcaaaaa ataaaaagct 56161 gaagatattc tcagtgaaga ttcctttgtc ttcttataca gcgcaggtat gccgccgatt 56221 accgcgccca ggaaaaacat ggacacgggc accggaaatt tctccaaaag ccattttata 56281 agaaatgaaa gggaacaaat tcccaaacct gccccaatgc aaaactttac taaaaacaac 56341 acattgcctt tgatgtcttt taaaaaatta ctgattgagc tgatcagcct gtcataaatc 56401 cccaacagaa tggccatggt gccgccgctc actccgggga cgctcatgga tgaacctatt 56461 atatatccct tcactattgt gaacaaatca tctttcaatc cgctcttcat ctacacaaac 56521 acacctttta ccggtgtgta cacctccttt ttatccaagt cactgatgaa aattataaca 56581 ttatgcactt gatatgtaaa taaccatctc ttttaaagtc tgatttcggc tttaaactct 56641 tatctctgtt ctgctttcgg ttttatatca ctcttgcttt tattccggtt ttgatttcat 56701 tttatctttg attttatttc aattttgctt cattctcgct tttatttcac tatttctttt 56761 tacttcactt tcgccctggc atcgattatc ttttcaaaat caatattgct ttcacccctt 56821 tttactttat ttatggtttt gttaatataa acacaaagtt tttcctcaaa aatctccgca 56881 gtggtttcct tgttctcaat cattgcaaga cctttttccc aactggctgt aagcgacgga 56941 ctcaaaagct ctctggccgt cctccttacc agttcaacaa tggcctcacc ttttaaagtg 57001 ggagttacca cctgggtttt gggatttatt tttatatagc ctatatcgct aagtttcttg 57061 attataccgg cccgagtggc ggaagtgccg attccgcagg tttttatctg ttctctcagc 57121 tcctcatcct ctatgaattt tcccgctttc tccatggtaa ttatcagtga accatcggta 57181 tatcgggaag gaggtttggt ctctttttcc tcaagctcaa agtcttttgc ttccactgct 57241 tcatttttca ccaaaagatg tataggcgcc tccgtcaatt cttcgtcctg ttttggcgca 57301 ctgacctcgt aaacttcttt ccagcctgct tctttaaggg ttttggcatt ggaaacaaaa 57361 atttcgttgt ttaccaccgt ctccacccgg accgtattgt ataccgccgg gggaaagaaa 57421 attgccagaa atcttttcac aataaggttg tacacatttt tcgtattctc atccatgcgt 57481 accgtttcag cgtttacata cgtcgggatt atcgcatagt ggtccgtaac cttgctgttg 57541 tcaacatacc tttttgtaga ttttgtgacc ttaaggtctc ccatttcctt tattttcagc 57601 acataatccc tgtactccgg atttttgtaa atcccgttta agaccttggg cacttcttcg 57661 agaacatcgg ttgaaattac cctgctgtcg gttctggggt aggtaatcag ctttttttca 57721 tacaaccatt gggcaatttc caaagtcttg tccaccggaa gtttaaactt tttgtttgcc 57781 tccgactgaa gctccgccag gttaaataaa aggggaggct gctctttttt tgtctttacc 57841 tcaacttttt ttattttccc cgggtgtcct ttaagccttt caataacctg ctccgcttcc 57901 tcccggctaa tgtacttttc ctcatcgtcc gcttctttgt cgtccttttt attctggggc 57961 acccatttgc ctttgtataa aagattgctg acagaggaca gaaacgttgc ggtgatgcca 58021 taatgctttt tgggcataaa gtttcttatc tcctgctccc tgtccacgac aagccccagc 58081 acacatgtca tgactcttcc gattgctata acggaggttt tgctctcctt taaaaagttt 58141 gacaactttc ttccatacag acaagtgtaa atcctgctga agttcatccc aaaaagccaa 58201 tcctctttag ccctgctgta ggcagccctg gccaaagagt catattcctc tatatccttt 58261 gcattgagaa ttccttccct tatggcttcc tcagtctgag aagaaatcca aactcttttt 58321 gctttcttat tgcttccgct ctgttcatat acaagcctga aaatatattc tccttcgcgg 58381 ccgctgtcgg tacaggcgaa tattaaatct atatcttccc tgttcattaa tgtctttatg 58441 gtttcaaact gttttttgat cccttcgtcg tcaataacaa tatacttgta tactttgggg 58501 attataggga gatcttccac cttccattcc cggtatttcg ggtcataagc atcaggatat 58561 gccattgtga taagatggcc aaaacaccat gttaccactg agtgctccga ctcggcatat 58621 cccttgcttc tgtcctgttt tgtaattttc atgcccaaaa cttcggcaaa acttgcagcc 58681 accgaaggct tttccgtaat atagagtttt ttacccaaac cgcatctcct tatacatcaa 58741 ttatttgtta tttttatgtc aaattttatc atcgctcaga gacttcagta ttatttattt 58801 tacattaaac agacagccgc ttcaaccata gaaaaagcag taccagcctt tcgcacggtt 58861 attacaaaac cgtcaaatgt cctctcgttt taattcctcc tataccttta cttcctgata 58921 ttgtcagttt gctgacttcc tcgggagtta cataattatc tttatttgta agtgccactt 58981 tttccgacac aatggcagga tctaaagcgt tgatatttat tctcccgggt gagcttgcga 59041 aattggctcc ggcctgcatg atggcctcaa aatatgattg gcacgcaccg gcaaatatgc 59101 acaatttatc gtaatcaggc tgatattttc ttgcctcttt gacacattca atgaaatact 59161 ttgagtttct gtaactgtca agtaaattcg ggtcgctgcc tttcttcaag ctgtcatgac 59221 ctgttaccac aagtatgtcc ggtttggtct ccgcaagagc cctctttatg atattgggct 59281 gttcactctc aggcgcaagg tattccctgg atgtgatacc tgcctcctta tatagatttc 59341 tgcacatttt taaaaaactt tcactggaat cgatatgaag aacctttccg ggcctctgcc 59401 ggggtttgct gaacaggaag catctgctgg taaatatttg cctgtaagca ttgcttcttg 59461 ccattgtcaa atctcttctc aaatttatgc gcgtgcttct ggaatctttc tttacaaggt 59521 catcctcaaa agcatccact attatcctgt agaataatcc tcttagaatg tagacaggct 59581 tggaagaatc tttgttttga atatcggtta cgataaagta gatatcctga ccgtgagatt 59641 ttcttgttac tatatctcca atttttaaca ttgacataat aaacccccta caaagatatt 59701 tgcatattgc ataatatgca aataaatctt cataggaggc ttgttaacat aaattttatg 59761 catgcaagtt tattaatttt tatatttatt attaattgtc tatatcagtt atgactttat 59821 ataaatcccc ccgttttata taaccccctg ttgcattgtc tctaatactt cataagcttg 59881 caaatgaccg ttaccgcttc cgctcttgtg gtaagccctt tgggatcaaa catgttgccg 59941 ggttttccga ccatcaaccc ttgagatacc acagccgcca ccgaatcccg cgcatattcc 60001 gagatattgc cgctgtcggc aaaaaccaga ccttttccca ttccttccag gtttccgtca 60061 tgttttttct ccaaaaactt ggcaataacc actgccatat cctgtctggt tataaattca 60121 tttggagcaa aacttccgtc gggtcttccg acaactattc caaaggctgc ggcggaagac 60181 acgctcttgt aataccagtc tttttcagtc acgtcgttga aatgcagtcc ggcttctctg 60241 taagggattt tcagggaatt aacaattatc tgtgtgaact cggcccttgt aataggtctt 60301 ccgggcatga acgttttttc atcaataccg cttataattc ccttttcata gagcttttga 60361 atatactctt ccgcccaata tcccctgggc acatcatcaa atatcccacc ctttgtcccg 60421 tctggactca cttcattttc cttaagcaaa tcctccaatg acgagaaaaa tggattgccg 60481 cttttatcag gagttggtgt aggcaattgc aatgcctcaa gtaaaacact tattcggtac 60541 gttcttgatg ttattccatc ttctgccaca actttaacaa tcagctcatt ttttccttcc 60601 ttaagctcaa cagcatggga tatacttccg cttttaacag gaacaccgtt taaagtaatc 60661 tcagctccgt catcccgtgc ataagcaaca atacacacaa accttacatc ttcctccgcc 60721 actgcctcgt aattcagtat atccggaaca aacgcaggtt taagctttgc tcctgtcaca 60781 acaaggtcgg aaaggtatgg atcgcttttg acctcaagag ttggggtcgg tgtcggcatc 60841 ggtgtcatgg ttggcgttgg agtcggaatc agtattggtt ccggtaccgg tgttgatatt 60901 ggtaccggtt ccggtgcagg gtttggcgct ggcgttggag tcggtgtcgg cgtcggtact 60961 ggagtcgagc ttgggctcag ttccggtgtc ggcgtcgggc ttgggctcgg ttccggctcc 61021 ggcgtcggtg tcgggctcgg ctccggttcc ggtgtcggcg tcgatgtcgg ctccggttct 61081 ggttccggtg tcggcgtcga tgtcggactc ggttccggct ccggcgtcgg tgtcgggctc 61141 g //