LOCUS       NZ_ACVX01000032        43259 bp    DNA     linear   CON 10-NOV-2010
DEFINITION  Clostridium thermocellum DSM 2360 ctg00041, whole genome shotgun
            sequence.
ACCESSION   NZ_ACVX01000032 NZ_ACVX00000000
VERSION     NZ_ACVX01000032.1  GI:256005510
DBLINK      Project: 55637
KEYWORDS    WGS.
SOURCE      Clostridium thermocellum DSM 2360
  ORGANISM  Clostridium thermocellum DSM 2360
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (bases 1 to 43259)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L.
            and Hemme,C.L.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The draft genome of Clostridium thermocellum DSM 2360
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 43259)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L.
            and Hemme,C.L.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800
            Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     PREDICTED REFSEQ: This record has not been reviewed and the
            function is unknown. The reference sequence was derived from
            ACVX01000032.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4085028
            Source DNA and Bacteria available from Christopher L. Hemme
            (hemmecl@ou.edu)
            Contacts: Christopher L. Hemme (hemmecl@ou.edu)
                 David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            
            ##Metadata-START##
            Organism Display Name :: Clostridium thermocellum DSM 2360
            Culture Collection ID :: DSM 2360
            GOLD Stamp ID         :: Gi02594
            Isolation Site        :: contaminant of Clostridium thermocellum
                                     strain LQ8
            Isolation Country     :: USA
            Oxygen Requirement    :: Anaerobe
            Cell Shape            :: Rod-shaped
            Motility              :: Motile
            Sporulation           :: Sporulating
            Temperature Range     :: Thermophile
            Temperature Optimum   :: 60 C
            Gram Staining         :: gram+
            Biotic Relationship   :: Free living
            Diseases              :: None
            Phenotypes            :: Cellulose degrader, Ethanogenic, Ethanol
                                     production
            Energy Source         :: Chemoorganotroph
            ##Metadata-END##
FEATURES             Location/Qualifiers
     source          1..43259
                     /organism="Clostridium thermocellum DSM 2360"
                     /mol_type="genomic DNA"
                     /strain="DSM 2360"
                     /isolation_source="contaminant of Clostridium thermocellum
                     strain LQ8"
                     /db_xref="taxon:572545"
     gene            complement(<1..690)
                     /locus_tag="ClothDRAFT_2333"
     CDS             complement(<1..690)
                     /locus_tag="ClothDRAFT_2333"
                     /inference="protein motif:PFAM:PF08928"
                     /note="PFAM: Domain of unknown function DUF1910; Domain of
                     unknown function DUF1911;
                     KEGG: pfl:PFL_2345 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="protein of unknown function DUF1910"
                     /protein_id="ZP_05430472.1"
                     /db_xref="GI:256005511"
                     /db_xref="InterPro:IPR015024"
                     /db_xref="InterPro:IPR015025"
                     /translation="MRDPLCSESYLLETIEFDKEAICERKKKIIMLKDDMEKGIQRYP
                     KDNQSIIYATYRGMFMYNTEILIAKYSLGSHPNEIIEDYLNGIEYLENVGNAEPWYVD
                     VLRMVSLGILLEVDKKDLKRLACAIEKQKIEDALLDFLLKACDIGWNHNTSRYERKNP
                     YAKTAEIIQMALHDKDKERASKRLQQYVEKEWIKGHNDLDWKNAHKKPGYVGLWSFEA
                     AALAKILGLDDS"
     misc_feature    complement(310..687)
                     /locus_tag="ClothDRAFT_2333"
                     /note="Domain of unknown function (DUF1910); Region:
                     DUF1910; pfam08928"
                     /db_xref="CDD:149863"
     misc_feature    complement(1..306)
                     /locus_tag="ClothDRAFT_2333"
                     /note="Domain of unknown function (DUF1911); Region:
                     DUF1911; pfam08929"
                     /db_xref="CDD:149864"
     gene            complement(717..1061)
                     /locus_tag="ClothDRAFT_2334"
     CDS             complement(717..1061)
                     /locus_tag="ClothDRAFT_2334"
                     /inference="similar to AA sequence:KEGG:RS02473"
                     /note="KEGG: rso:RS02473 putative hemagglutinin-related
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative hemagglutinin-related protein"
                     /protein_id="ZP_05430473.1"
                     /db_xref="GI:256005512"
                     /translation="MAYSNDEIVKGIDGIYSNENPNSNIKYVINESRFNASQLCKTKK
                     GIKQMSDEWLLEDGGKRILEAVNGDRKLQKDIIRVLNKGQVEKVLSRVGKDGKVTTYR
                     LNSNGEIIGFWP"
     gene            complement(1550..2683)
                     /locus_tag="ClothDRAFT_2335"
     CDS             complement(1550..2683)
                     /locus_tag="ClothDRAFT_2335"
                     /inference="protein motif:PFAM:PF08929"
                     /note="PFAM: Domain of unknown function DUF1911; Domain of
                     unknown function DUF1910;
                     KEGG: aha:AHA_1829 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="protein of unknown function DUF1911"
                     /protein_id="ZP_05430474.1"
                     /db_xref="GI:256005513"
                     /db_xref="InterPro:IPR015024"
                     /db_xref="InterPro:IPR015025"
                     /translation="MEKGIQRYPRDNQSIIYATFLHMFMYNTEMLTAKYSLGSHPDEM
                     IEDYLNGIEYLENVGEEKVWYIDLLWMLSLGILLEVDKQDLKRLACVIEKQKKEDALM
                     DFLLKACDIGWNHNTSEYERKNPYAKTAEIIQMALHDKDREKASKRLQQYIEKEWIKG
                     HNDLDFKNAHKEPGYVGLWSFEAAALAKILGLDDSALKDNNHYPYDLAHYKNGMSFDL
                     SWYGVPVEEEAKEEEAIVYGIPNNPELEQIIPAKFHSFVNEVIGDYNTLSDEEFWKKY
                     NLREIWFDVKEYEEDNKAKNMLGTIIVFLLVEKEYILQLDYKEDLVDYIEDIDNYWGK
                     EEVKLISFEVDNDQQYYAYVPKTAAIDSLYEVKLTEVEKIEEV"
     misc_feature    complement(2408..>2683)
                     /locus_tag="ClothDRAFT_2335"
                     /note="Domain of unknown function (DUF1910); Region:
                     DUF1910; pfam08928"
                     /db_xref="CDD:149863"
     misc_feature    complement(2063..2404)
                     /locus_tag="ClothDRAFT_2335"
                     /note="Domain of unknown function (DUF1911); Region:
                     DUF1911; pfam08929"
                     /db_xref="CDD:149864"
     gene            complement(2692..2787)
                     /locus_tag="ClothDRAFT_2336"
     CDS             complement(2692..2787)
                     /locus_tag="ClothDRAFT_2336"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430475.1"
                     /db_xref="GI:256005514"
                     /translation="MRDPLCSESYLLETIEYDKEGICKSKKRLLF"
     misc_feature    complement(<2698..2784)
                     /locus_tag="ClothDRAFT_2336"
                     /note="Domain of unknown function (DUF1910); Region:
                     DUF1910; pfam08928"
                     /db_xref="CDD:149863"
     gene            complement(2814..4169)
                     /locus_tag="ClothDRAFT_2337"
     CDS             complement(2814..4169)
                     /locus_tag="ClothDRAFT_2337"
                     /inference="protein motif:SMART:SM00306"
                     /note="SMART: Hedgehog/intein hint domain protein;
                     KEGG: hch:HCH_02073 rhs family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hedgehog/intein hint domain protein"
                     /protein_id="ZP_05430476.1"
                     /db_xref="GI:256005515"
                     /db_xref="InterPro:IPR003587"
                     /db_xref="InterPro:IPR006141"
                     /translation="MGVILAGAFWGALAGGLIGGAVGGIAAAINGGSFLEGFADGALS
                     GAVSGAVTGAACAGLGALGAAAGKGIQCMSTVGKAINVTSKVTAALSLGMDGFDMLAM
                     GVSLFDPSNALVEFNRKLHSNALYNGFQIAVNALAVFSAGAASTMKCFVAGTMVLTAA
                     GLVAIENIKVGDKVIAANPETFEVAEKTVLETYVRETTELLHLRIGGEVIKTTVDHPF
                     YVKDVGFVEAVNLQVGDKLVDSKGNVLVVEEKKLKITGKPVKVYNFKVDDFHTYHVGN
                     KGILVHNANYNPKTTFENLDLETASNKQKGNYGEYRADDNLINNPKLKEVGYDLEQIG
                     GKVPTSPDDKITKGIDGIYVNKNPNSNIKYVIDESKFNTAQLGKTKKGIKQMSDEWLR
                     EKQGKRILQAVNGDRRLKDDIIEALNNGAVEKVLSRVGKDGKVTTYRLNSNGEIIGFW
                     P"
     sig_peptide     complement(4098..4169)
                     /locus_tag="ClothDRAFT_2337"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 0.740) with cleavage site probability 0.231 at
                     residue 24"
     misc_feature    complement(3321..3725)
                     /locus_tag="ClothDRAFT_2337"
                     /note="Hedgehog/Intein domain, found in Hedgehog proteins
                     as well as proteins which contain inteins and undergo
                     protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In
                     protein splicing an intervening polypeptide sequence - the
                     intein - is excised from a...; Region: Hint; cd00081"
                     /db_xref="CDD:73181"
     misc_feature    complement(order(3321..3326,3522..3524,3723..3725))
                     /locus_tag="ClothDRAFT_2337"
                     /note="protein-splicing catalytic site; other site"
                     /db_xref="CDD:73181"
     misc_feature    complement(order(3522..3524,3531..3533,3723..3725))
                     /locus_tag="ClothDRAFT_2337"
                     /note="thioester formation/cholesterol transfer; other
                     site"
                     /db_xref="CDD:73181"
     misc_feature    complement(3318..3707)
                     /locus_tag="ClothDRAFT_2337"
                     /note="Protein of unknown function (DUF1557); Region:
                     DUF1557; pfam07591"
                     /db_xref="CDD:148935"
     gene            complement(4303..4656)
                     /locus_tag="ClothDRAFT_2338"
     CDS             complement(4303..4656)
                     /locus_tag="ClothDRAFT_2338"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: similar to RAB6-interacting protein 2 isoform
                     delta"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430477.1"
                     /db_xref="GI:256005516"
                     /translation="MATITLYAGKINQMPGLIKDVKKSVIDLKSELSALKKKTLNINR
                     SVCNLDDVIISIQASSQTQDKKVTSLDTVCKETEEFISEVVRVDSEVAELINKRKENF
                     YKEYYYLKPENEKSG"
     gene            complement(5072..5147)
                     /locus_tag="ClothDRAFT_R0038"
                     /note="tRNA-Thr1"
     tRNA            complement(5072..5147)
                     /locus_tag="ClothDRAFT_R0038"
                     /product="tRNA-Thr"
     gene            complement(5237..6532)
                     /locus_tag="ClothDRAFT_2339"
     CDS             complement(5237..6532)
                     /locus_tag="ClothDRAFT_2339"
                     /inference="protein motif:PFAM:PF01979"
                     /note="PFAM: amidohydrolase; Amidohydrolase 3;
                     KEGG: dal:Dalk_5014 amidohydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="ZP_05430478.1"
                     /db_xref="GI:256005517"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR013108"
                     /translation="MNILIKNADIITCNASDDVLQGAFLGIKDGYIDFIDTKEDALKD
                     FKADRIIDAKGKLVMPGLVNAHTHSGMTILRNFANDLALEDWLFGNVLPVEEKLTPED
                     IYWGTLLGIAEMIKSGTTTFADMYLHMEEVARAVSETGIRANLCRSPLKDSDKSVEDA
                     VRCFEYFKKWDNSFNGRIKVYIEVHSVYLFDEPSLRMSAEVAKEINTGIHIHVQETLK
                     ECEDSNKKYGMSPAEICCKTGIFDVPVIAAHCVHLSDGDMGIIRDKGVNVIHNPTSNL
                     KLGSGIAKVDDMLKNGINVALGTDGAASNNNLNMFEEMHLAALIHKGVHMDPTLIGAS
                     CALKMATVNGAKALGFGGEIGEISKGMKADLILIDMDKTHLCPVNDPVSAVVYSAQSS
                     DVDTVIIDGNIVMENRELKTIDEEKVKFNVKEIAKRVLR"
     misc_feature    complement(5252..6529)
                     /locus_tag="ClothDRAFT_2339"
                     /note="N-ethylammeline chlorohydrolase; Provisional;
                     Region: PRK06038"
                     /db_xref="CDD:180363"
     misc_feature    complement(5300..6526)
                     /locus_tag="ClothDRAFT_2339"
                     /note="TRZ/ATZ family contains enzymes from the atrazine
                     degradation pathway and related hydrolases. Atrazine, a
                     chlorinated herbizide, can be catabolized by a variety of
                     different bacteria. The first three steps of the atrazine
                     dehalogenation pathway are...; Region: ATZ_TRZ_like;
                     cd01298"
                     /db_xref="CDD:30041"
     misc_feature    complement(order(5633..5635,5786..5788,5888..5890,
                     5897..5899,6329..6331,6335..6337))
                     /locus_tag="ClothDRAFT_2339"
                     /note="active site"
                     /db_xref="CDD:30041"
     misc_feature    complement(order(6089..6094,6155..6160,6248..6250,
                     6257..6259))
                     /locus_tag="ClothDRAFT_2339"
                     /note="putative substrate binding pocket; other site"
                     /db_xref="CDD:30041"
     gene            complement(6624..7868)
                     /locus_tag="ClothDRAFT_2340"
     CDS             complement(6624..7868)
                     /locus_tag="ClothDRAFT_2340"
                     /EC_number="3.3.1.1"
                     /inference="protein motif:TFAM:TIGR00936"
                     /note="KEGG: sfu:Sfum_0366 adenosylhomocysteinase;
                     TIGRFAM: adenosylhomocysteinase;
                     PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding;
                     S-adenosyl-L-homocysteine hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylhomocysteinase"
                     /protein_id="ZP_05430479.1"
                     /db_xref="GI:256005518"
                     /db_xref="InterPro:IPR000043"
                     /db_xref="InterPro:IPR015878"
                     /translation="MGSVIRDISLAKSGRQKINWVRKNMPLLRSLEEEFAKTKPFDGI
                     RITVSVHLEAKTAYLAKLFAIGGGQVSVTGSNPLSTQDDVAAALAEDGLNVYAWYNAT
                     EKEYKEHLNLALDGRPNIVIDDGGDLVHLLHTERTELLSDVMGGCEETTTGVIRLKAM
                     EKEGALKFPMVAVNNAYCKYLFDNRYGTGQSVWDGINRTTNLIVAGKNVVVVGYGWCG
                     KGIAMRAKGLGASVIVCEVDPIKAAEAVMDGYKVMPMMEAAKIGDLFITATGCSRVIH
                     REHFKVMKDGAILCNAGHFDVEVSVKDLEEMAVRKEEQRKNIMGYMMEDGRWINLLAE
                     GRLVNLAAGDGHPAEIMDMSFALQALSAKYVLENHSRLGKKVIDVPEEIDRRVALMKL
                     ESWGITIDELTEEQKKYLDSWC"
     misc_feature    complement(6630..7868)
                     /locus_tag="ClothDRAFT_2340"
                     /note="S-adenosyl-L-homocysteine hydrolase; Provisional;
                     Region: PRK05476"
                     /db_xref="CDD:180110"
     misc_feature    complement(6630..7847)
                     /locus_tag="ClothDRAFT_2340"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:186874"
     misc_feature    complement(order(6639..6644,6651..6656,6663..6665,
                     6669..6677,6681..6686,6693..6695,6735..6737,6819..6821,
                     6837..6839,6930..6932,6978..6980,7011..7019,7050..7061,
                     7110..7115,7122..7133,7137..7163,7182..7187,7248..7262,
                     7266..7268,7275..7280,7299..7304,7311..7313,7323..7325,
                     7338..7340,7344..7346,7392..7397,7404..7406,7797..7802,
                     7821..7823))
                     /locus_tag="ClothDRAFT_2340"
                     /note="oligomerization interface; other site"
                     /db_xref="CDD:29522"
     misc_feature    complement(order(6831..6833,7320..7322,7332..7334,
                     7419..7424,7497..7499,7704..7706,7710..7712,7716..7718))
                     /locus_tag="ClothDRAFT_2340"
                     /note="active site"
                     /db_xref="CDD:29522"
     misc_feature    complement(order(6831..6833,6852..6854,6858..6860,
                     6987..6995,7047..7049,7062..7067,7158..7166,7218..7226,
                     7230..7232,7317..7319,7413..7421))
                     /locus_tag="ClothDRAFT_2340"
                     /note="NAD+ binding site; other site"
                     /db_xref="CDD:29522"
     gene            complement(7872..8699)
                     /locus_tag="ClothDRAFT_2341"
     CDS             complement(7872..8699)
                     /locus_tag="ClothDRAFT_2341"
                     /inference="protein motif:TFAM:TIGR01700"
                     /note="TIGRFAM: purine nucleoside phosphorylase I, inosine
                     and guanosine-specific; inosine guanosine and xanthosine
                     phosphorylase family;
                     PFAM: purine or other phosphorylase family 1;
                     KEGG: purine nucleoside phosphorylase I, inosine and
                     guanosine-specific family protein; K03783
                     purine-nucleoside phosphorylase"
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphorylase I, inosine and
                     guanosine-specific"
                     /protein_id="ZP_05430480.1"
                     /db_xref="GI:256005519"
                     /db_xref="InterPro:IPR000845"
                     /db_xref="InterPro:IPR001369"
                     /db_xref="InterPro:IPR011268"
                     /db_xref="InterPro:IPR011270"
                     /translation="MDNIYEKARETASFIKRIIKETPEIAIVLGSGLGPLADEIENKV
                     EIDYKDVPNFPVTTVEGHAGKFVYGILENRRVIAMKGRFHHYEGYDVSQIVFPVRVFK
                     MLGINNLIVTNASGGINRSFRPGDLMIIKDHISFFAPSPLRGKNIDEFGLRFPDMCKA
                     YNPKLVEICKKAASDVGVDVKEGVYAFTQGPMYETPAEIRALGILGADAVGMSTVPEV
                     IAARHANMNILGISCITNMAAGILDQPLTHEEVMKTAKEAENKFVRLVKRVISVWEV"
     misc_feature    complement(7890..8687)
                     /locus_tag="ClothDRAFT_2341"
                     /note="Phosphorylase superfamily; Region: PNP_UDP_1;
                     cl00303"
                     /db_xref="CDD:185889"
     gene            complement(8863..10038)
                     /locus_tag="ClothDRAFT_2342"
     CDS             complement(8863..10038)
                     /locus_tag="ClothDRAFT_2342"
                     /inference="protein motif:PFAM:PF07690"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     proton/sugar symporter LacY; nucleoside:H symporter;
                     KEGG: dal:Dalk_2885 major facilitator superfamily MFS_1"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator superfamily MFS_1"
                     /protein_id="ZP_05430481.1"
                     /db_xref="GI:256005520"
                     /db_xref="InterPro:IPR000576"
                     /db_xref="InterPro:IPR004740"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /translation="MILDNLKRSERYPFSFILFYSLFYMGLAVFGVFMPVYLEGLGYD
                     NTDIGTFLSISSFVGLFAQPIWGVISDRAKSKNNVLKMLVLFSSIAIFMFRLSGNYYY
                     IFAVMVVYAFFQTPITPIGDAITLEYITDTKWKYGPIRLAGALGYAVMAFIGGALTRK
                     NINAIFFICFVIGIMSLITVFRMPTVKGHQSDGNKLSILEVFKNSELVLLMGFTLVIH
                     TTMGFYNTFFPIYYKNMGADNTILGLAVFIGSASEIIFLVFGDRIIKRLGIKFTLFGA
                     AVVAVVRWASLGLINNIFAVLALQILHGFIFIVLAYSMATYINNEMPPELKASGQTVN
                     SVIGLGISRIIGSTGGGVISDLIGIRQVFFLNSVIVLASIVIFGAIFLVRRQKITGQ"
     misc_feature    complement(8878..9999)
                     /locus_tag="ClothDRAFT_2342"
                     /note="galactoside permease; Reviewed; Region: lacY;
                     PRK09528"
                     /db_xref="CDD:181931"
     misc_feature    complement(9037..9999)
                     /locus_tag="ClothDRAFT_2342"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(9037..9039,9046..9051,9082..9084,
                     9091..9096,9106..9108,9115..9120,9127..9129,9268..9270,
                     9280..9282,9289..9291,9301..9303,9313..9315,9352..9354,
                     9361..9366,9373..9378,9385..9387,9598..9600,9616..9621,
                     9628..9633,9661..9663,9670..9675,9682..9687,9694..9699,
                     9838..9843,9847..9852,9862..9864,9871..9876,9883..9885,
                     9934..9939,9943..9951,9958..9960))
                     /locus_tag="ClothDRAFT_2342"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(10196..11584)
                     /locus_tag="ClothDRAFT_2343"
     CDS             complement(10196..11584)
                     /locus_tag="ClothDRAFT_2343"
                     /inference="protein motif:PFAM:PF04293"
                     /note="PFAM: SpoVR family protein;
                     KEGG: noc:Noc_2507 stage V sporulation-like protein,
                     SpoVR"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="ZP_05430482.1"
                     /db_xref="GI:256005521"
                     /db_xref="InterPro:IPR007390"
                     /translation="MAEYSMKELIEWNEKIEEIARAEGLDYYEQEFEICSYEDMIAYE
                     TYVGMPSHYPHWSYGKNYERIKTLYKYNLTGLPYEMVINSDPCIAYLMKDNTLLLQIL
                     TMAHVYGHNDFFKNNRLFKLGTRAKDTVDMFKNHADRIREYIQDPGIGYAKVEKILNA
                     AHAIRYQISRNIGVRVLSQEEKKKELLERYNKPKSEYPLLEPKSKEEEAPPDFKKIPV
                     EPEEDMLLFFMNYSKLTDWERDILSIVREETLYFLPQIETKIMNEGWASFWHYNILNK
                     LNLEQGLHFEFLKRHNQVIRPVLGQLNPYYIGFRIFEDLKKRYEDDPKKIFEVREVER
                     DQSFIRRYLTRELCEEMNLFEYAKIGNSYIVTEVSDEEGWKKIRDTIANNVGLAGIPV
                     IKVAEWVQKDNTLVLEHEYDGREIELSYAYETMKHIVDLWDGKVMLGTVIDNKKKIIV
                     CNEQKKVTLTDG"
     misc_feature    complement(10217..11584)
                     /locus_tag="ClothDRAFT_2343"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: SpoVR; cl01044"
                     /db_xref="CDD:186307"
     misc_feature    complement(10376..11584)
                     /locus_tag="ClothDRAFT_2343"
                     /note="SpoVR like protein; Region: SpoVR; pfam04293"
                     /db_xref="CDD:146761"
     gene            complement(11607..12821)
                     /locus_tag="ClothDRAFT_2344"
     CDS             complement(11607..12821)
                     /locus_tag="ClothDRAFT_2344"
                     /inference="protein motif:TFAM:TIGR02877"
                     /note="TIGRFAM: sporulation protein YhbH;
                     PFAM: protein of unknown function DUF444;
                     KEGG: noc:Noc_2508 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YhbH"
                     /protein_id="ZP_05430483.1"
                     /db_xref="GI:256005522"
                     /db_xref="InterPro:IPR006698"
                     /db_xref="InterPro:IPR014230"
                     /translation="MAIFREYVSGGKDRAAEDRRRHRELVEESIKKNIGNIIAEESII
                     GQSKDKKIKIPIRSIKEYQFVYGKNGPSVGSGDGTEKRGEKIGEEKTANGGQGVGQAG
                     NQEGEEIYETEITIEELINYLFDDLNLPDIDKKRIAEQESIRSYKNLGYQRKGIPPRL
                     AKKRSVIEKIKRKQAYLRNSRELGDLDESAEEDIAAQETLDGVRKRFPFSEDDLRYRR
                     VREDRKKDFNAVVICIMDVSGSMDQTKKYLARSFYFLLYQFIRLKYANVDVVFIAHTT
                     TAKEVSEDEFFHRGESGGTYISSGYEKALEIIEQRYNPNSWNIYAFHCSDGDNWSEDN
                     KKAVELGLKLCDVCNLFGYGEIVPGYYSTGSTIKDEFQKSIKRDNFSVITITNKDDVL
                     PGLKKLLEKEGE"
     misc_feature    complement(11643..12821)
                     /locus_tag="ClothDRAFT_2344"
                     /note="Protein of unknown function (DUF444); Region:
                     DUF444; pfam04285"
                     /db_xref="CDD:113071"
     misc_feature    complement(11643..12746)
                     /locus_tag="ClothDRAFT_2344"
                     /note="Von Willebrand factor type A (vWA) domain was
                     originally found in the blood coagulation protein von
                     Willebrand factor (vWF). Typically, the vWA domain is made
                     up of approximately 200 amino acid residues folded into a
                     classic a/b para-rossmann type of...; Region: vWFA;
                     cl00057"
                     /db_xref="CDD:185787"
     gene            complement(12863..14791)
                     /locus_tag="ClothDRAFT_2345"
     CDS             complement(12863..14791)
                     /locus_tag="ClothDRAFT_2345"
                     /inference="protein motif:PFAM:PF08298"
                     /note="PFAM: PrkA AAA domain protein; PrkA serine kinase;
                     SMART: PrkA AAA domain protein;
                     KEGG: noc:Noc_2509 PrkA serine kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative serine protein kinase, PrkA"
                     /protein_id="ZP_05430484.1"
                     /db_xref="GI:256005523"
                     /db_xref="InterPro:IPR010650"
                     /db_xref="InterPro:IPR013153"
                     /translation="MERLDFSSIIRKDREEHKSKKFEGTFLEYLEIVKENPEITMLAH
                     QRMYKLITEPGVTVIRTEENPRLRRIYGNDIIKKYKFFEDEFFGIDKTIMKIVRYFHS
                     AAMAGEEARQVLYLVGPVGAGKSSLMEALKRALEMSPPIYALKGCPMREEPLHLVPKH
                     LRKEFEEILNVRIEGDLCPICRYRLKNEYNGEYERFPVETVDFSIRSRKGIGVVPPVD
                     PNNQDTSVLIGSVDISKIDLYPEDDPRVLSLNGAFNVGNRGIVEFIEVFKNETEYLHT
                     MITATQEKSIPSPGKGSMIYFDGIILAHSNEAEWNKFKSDHTNEAILDRIVKIEVPYC
                     LELNEEIKIYEKILRKSKFDAHIAPHTIEIAAMFAILTRLAPSNKVDPMTKLKIYNGE
                     EIIEKGMTKKVDIFELKEEAPREGMTGISTRFIMKVLDTTLSESEHNCINPISVMETL
                     VKSIKELSISEEERERYLRFVQDSIRKEYNKILEREITKAFIHGYKEQAESLFNNYLD
                     HAEAFVNKSKIKDRNTGEELEPDEKFLRSIEEQIGITDTAAKGFRADVTAYMFYVLRN
                     GGKLDYTSYEPLKEAIEKKLTSSVRELSRVITQAKVRDKEQSEKYDTMVQEMKNNGYC
                     DHCCNVILKYAANNLWKD"
     misc_feature    complement(12866..14782)
                     /locus_tag="ClothDRAFT_2345"
                     /note="Putative Ser protein kinase [Signal transduction
                     mechanisms]; Region: PrkA; COG2766"
                     /db_xref="CDD:32629"
     misc_feature    complement(13649..14722)
                     /locus_tag="ClothDRAFT_2345"
                     /note="P-loop containing Nucleoside Triphosphate
                     Hydrolases; Region: P-loop NTPase; cl09099"
                     /db_xref="CDD:158411"
     misc_feature    complement(12890..13645)
                     /locus_tag="ClothDRAFT_2345"
                     /note="PrkA serine protein kinase C-terminal domain;
                     Region: PrkA; pfam06798"
                     /db_xref="CDD:148418"
     gene            15298..16821
                     /locus_tag="ClothDRAFT_2346"
     CDS             15298..16821
                     /locus_tag="ClothDRAFT_2346"
                     /inference="protein motif:COG:COG5305"
                     /note="KEGG: sea:SeAg_B1520 putative inner membrane
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein-like protein"
                     /protein_id="ZP_05430485.1"
                     /db_xref="GI:256005524"
                     /translation="MKFKIPKLDYKSIIIWSVILIAGFWYLTRGISHETLWYDESYSA
                     AIINHSIPDIIRITANDSHPPLYFIMLKIFSSVFGRTESALRLFSVLGLLALATLGAG
                     PVRRVFGKFMGMMYSFCVIAVPISLSIGQETRMYTWAAFFVTAGALYGYLALQENKRS
                     DWIKFGLATLASAFTHYYALLAVTVLNVLLFVWLLLRFITTKDKKKFTSYLITAGAVV
                     LCYFPWIFILFGQAKKVSKSFWIPPVTKDVIWYTLQYPFAAKFWTFRFSRVCFICAVV
                     LILWGLIFSVIKRKKQGLMSLLAVLIYTLTLVSAIVLSNVIRPLLVERYIFPVVGLFV
                     LAFAYGISMLNSKGASIFVCVALLAVSISQNQLIIEKRFNGPMKEVCSYINSQNITPE
                     DVFIHTDEHTFGTFCYYYPNNKHYLYLPPDFDGYSGYDAFSPAGSYGSDIKEFIDGRE
                     KIWFVEREGSDMSKQGSKLLDKHILQSRGMILKFNLYPHSFYAVTLRRVVPGNALKD"
     misc_feature    15439..>16344
                     /locus_tag="ClothDRAFT_2346"
                     /note="Dolichyl-phosphate-mannose-protein
                     mannosyltransferase; Region: PMT; cl01961"
                     /db_xref="CDD:186501"
     gene            complement(16969..17085)
                     /locus_tag="ClothDRAFT_2347"
     CDS             complement(16969..17085)
                     /locus_tag="ClothDRAFT_2347"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430486.1"
                     /db_xref="GI:256005525"
                     /translation="MSLVEKLINDFEQLSEEKKKEVIHFVEFLKLKERKEKK"
     gene            complement(17112..17474)
                     /locus_tag="ClothDRAFT_2348"
     CDS             complement(17112..17474)
                     /locus_tag="ClothDRAFT_2348"
                     /inference="protein motif:PFAM:PF00583"
                     /note="PFAM: GCN5-related N-acetyltransferase;
                     KEGG: swd:Swoo_3070 GCN5-related N-acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="GCN5-related N-acetyltransferase"
                     /protein_id="ZP_05430487.1"
                     /db_xref="GI:256005526"
                     /db_xref="InterPro:IPR000182"
                     /translation="MDTLKIITDRLIITEFNVSMAEIVHENIGYVQAVPIGDEWEVGY
                     HIASKYTGNGYATEAVKAFVPLIMKRLNIKRIWGICRGDNIASCRVLEKCSFSLKEKC
                     FGDYKGQNQEIYKYVYEM"
     misc_feature    complement(17187..17414)
                     /locus_tag="ClothDRAFT_2348"
                     /note="N-Acyltransferase superfamily: Various enyzmes that
                     characteristicly catalyze the transfer of an acyl group to
                     a substrate; Region: NAT_SF; cl00443"
                     /db_xref="CDD:185998"
     gene            17702..19501
                     /locus_tag="ClothDRAFT_2349"
     CDS             17702..19501
                     /locus_tag="ClothDRAFT_2349"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /note="KEGG: rty:RT0097 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430488.1"
                     /db_xref="GI:256005527"
                     /translation="MNNLYKYTKNIALFITSSLAGIILFVWIMSINLGTSVMTSGFHK
                     KLLEKNNIYDEVQNEINNLVQSIFTDLSRQLPQLGDQQEEILAILEGSISPQMVKTNL
                     DTIADGLFKYFNGEKSFLPDIIIDTDPTSLQSSNAAEGDSSEDTSDITNSEYVLSKIK
                     RVNLNAILLSINRSDILDMLLFIKLIYFIMDFAPVFCALLLLLLFLKSLLLGKNIKEM
                     LNWLFRVLMTCSILCIITAIFCLVYSYKILPGNIYMLSVAIPLKSEVLLSYIRDCFVP
                     LFVFFTASGILMVLLAFLVVSLNKVANKFSSVNINIFKFKNFSIKHKKILKYTTIMLL
                     LIFSLSLFCFELYSFKKEFESNNFSNLISRLTNSNSYTEVISAKDDTIYMLQIKLVDA
                     KDNSPILGIQINVNGKTDNPEKYYNIAGETDETGTVKFTLGKGTFHLAFSPAEGSTDY
                     ILPSPFFYELKSVGTTMLTVNLSKNQALTQSTGITEIEVLDENNHPVEGIELYVDSEK
                     NSPQHPEPTPSADVLHSASSKNPEPSGNPDRFFSVTNEEGIAVFKLPSGIYNVKFSPD
                     KLPKDYKAPELFEINCSPNLTTRYTIRLVKSPR"
     sig_peptide     17702..17821
                     /locus_tag="ClothDRAFT_2349"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 0.745) with cleavage site probability 0.321 at
                     residue 40"
     gene            19579..20157
                     /locus_tag="ClothDRAFT_2350"
     CDS             19579..20157
                     /locus_tag="ClothDRAFT_2350"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430489.1"
                     /db_xref="GI:256005528"
                     /translation="MDYYYYPFVSDPYAVYTPNVWQSQGADELYLYSMPAIERQPQPV
                     LSNAPAQTSIVLFKELTGYPNYGNPSGNADILYTGNRGTWTFDIQPILLIPGNLTAQL
                     VIRGVLDDHTNVPVANYSARITINGTVVHTGRLPLVHGSPAGQRFNNWRLLTFNVPNL
                     RRNNTVVIQNTSNTGPNDWIAFDWMELRLQPR"
     gene            complement(20305..21669)
                     /locus_tag="ClothDRAFT_2351"
     CDS             complement(20305..21669)
                     /locus_tag="ClothDRAFT_2351"
                     /inference="protein motif:TFAM:TIGR01415"
                     /note="TIGRFAM: pyridoxal-phosphate dependent TrpB-like
                     enzyme;
                     PFAM: Pyridoxal-5'-phosphate-dependent protein beta
                     subunit;
                     KEGG: glo:Glov_1213 tryptophan synthase subunit beta"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate dependent TrpB-like enzyme"
                     /protein_id="ZP_05430490.1"
                     /db_xref="GI:256005529"
                     /db_xref="InterPro:IPR001926"
                     /db_xref="InterPro:IPR006316"
                     /translation="MSKKDVTKVVLDESDIPKQWYNILADMPNKPAPYFSSKTGKPVT
                     LDELQAIFPMELIQQENSQERWIDIPEEVREMYRQWRPSPLYRARALEKHLGTPARIY
                     YKYEGTNATGSHKLNTSLPQAYYNKIAGIKRLSTETGAGQWGSALSLACNHFGLECTV
                     YMVKVSYEQKPYRRSFMKTFGAQVYASPTNLTSSGRAILEKDPDCTGSLGIAISEAVE
                     DAATHDDTNYALGSVLNHVCLHQTIIGLEAKKQLEYLDEYPDVVFACCGGGSNFAGIA
                     FPFLMDKFKGTKVRAVAVEPTACPTLTKGVYAYDYSDTGKIGPLAKMYTVGHDFVPAG
                     IHAGGLRYHGVSPIVSQLYEDKLIEAKAYGQSSVFEAAVIFARTEGIVPAPESSHAIR
                     AAIDEALLCKESGEAKVILFNLSGHGYFDMAAYDNYFSGKLSDVDYSEEEIARSMKNL
                     PKVD"
     misc_feature    complement(20395..21516)
                     /locus_tag="ClothDRAFT_2351"
                     /note="Tryptophan synthase-beta:  Trptophan synthase is a
                     bifunctional enzyme that catalyses the last two steps in
                     the biosynthesis of L-tryptophan via its alpha and beta
                     reactions. In the alpha reaction, indole 3-glycerol
                     phosphate is cleaved reversibly to...; Region:
                     Trp-synth_B; cd06446"
                     /db_xref="CDD:107207"
     misc_feature    complement(20407..21423)
                     /locus_tag="ClothDRAFT_2351"
                     /note="Cysteine synthase [Amino acid transport and
                     metabolism]; Region: CysK; COG0031"
                     /db_xref="CDD:30381"
     misc_feature    complement(order(20425..20427,20512..20514,20857..20871,
                     20974..20976,21244..21246,21325..21330))
                     /locus_tag="ClothDRAFT_2351"
                     /note="pyridoxal 5'-phosphate binding site; other site"
                     /db_xref="CDD:107207"
     misc_feature    complement(21325..21327)
                     /locus_tag="ClothDRAFT_2351"
                     /note="catalytic residue; other site"
                     /db_xref="CDD:107207"
     gene            complement(21937..22875)
                     /locus_tag="ClothDRAFT_2352"
     CDS             complement(21937..22875)
                     /locus_tag="ClothDRAFT_2352"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430491.1"
                     /db_xref="GI:256005530"
                     /translation="MDNKKEVLSTGNEGVKNLMETITSKISVDQSKEILSNLKDSIVE
                     NIHERRERATSFINSLKKDKIRNLERLLDVTKRDLKKADKKNYIYITEAGRMVVVDRD
                     MWGDPCTVTIKEGNKVFLRMVKFFKDYPYLFPVFNEKNLNGDIIYMNDGEIWYRDKDV
                     ATLVLFKNEKPDFLTINLDKVKAFKEDELLKYLENCKILYLEKKLSDLLLEERKIAVE
                     DIVRVRPGYALYKNNEKTYTILLFDQFKNLCDEFTLRKLPNLSEAALDVLFSLDIVEY
                     VKSKGYAFENFKQDDDYIEYWQEIGSKRVCVMRCKI"
     gene            complement(23548..23928)
                     /locus_tag="ClothDRAFT_2353"
     CDS             complement(23548..23928)
                     /locus_tag="ClothDRAFT_2353"
                     /inference="similar to AA sequence:KEGG:Tola_0310"
                     /note="KEGG: tau:Tola_0310 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430492.1"
                     /db_xref="GI:256005531"
                     /translation="MVLFLIGLASGIISGMGIGGGAILIPALVFFVNPDQHIAQSVNL
                     LFFIPTAVIALIVHIKNKRVNFKLTIPIVIFGLVGAFLGSKLAVSLSGASLKRYFGMF
                     LLILGFYEMVRKDKKETKKQGGRA"
     misc_feature    complement(<23551..23847)
                     /locus_tag="ClothDRAFT_2353"
                     /note="Predicted permeases [General function prediction
                     only]; Region: COG0730; cl00498"
                     /db_xref="CDD:186038"
     gene            complement(23958..24329)
                     /locus_tag="ClothDRAFT_2354"
     CDS             complement(23958..24329)
                     /locus_tag="ClothDRAFT_2354"
                     /inference="similar to AA sequence:KEGG:Tgr7_2424"
                     /note="KEGG: tgr:Tgr7_2424 protein of unknown function
                     DUF81"
                     /codon_start=1
                     /transl_table=11
                     /product="protein of unknown function DUF81"
                     /protein_id="ZP_05430493.1"
                     /db_xref="GI:256005532"
                     /translation="MKGKIPISQYLKFAVIGLVTGIANGLFGSGGGTIVVPAMVLLLK
                     EEEHVAHATAISIILPLTLVSAFIYVSNSYIDWNLTVKTMLGGIVGGYLGAKLLNVCP
                     SHVLRKIFAVFIIAAAVRMII"
     misc_feature    complement(24006..>24293)
                     /locus_tag="ClothDRAFT_2354"
                     /note="Predicted permeases [General function prediction
                     only]; Region: COG0730; cl00498"
                     /db_xref="CDD:186038"
     gene            24630..24929
                     /locus_tag="ClothDRAFT_2355"
     CDS             24630..24929
                     /locus_tag="ClothDRAFT_2355"
                     /inference="protein motif:PFAM:PF02617"
                     /note="PFAM: ATP-dependent Clp protease adaptor protein
                     ClpS;
                     KEGG: sat:SYN_02377 ATP-dependent Clp protease adaptor
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adaptor protein ClpS"
                     /protein_id="ZP_05430494.1"
                     /db_xref="GI:256005533"
                     /db_xref="InterPro:IPR003769"
                     /translation="MSEKTIVKKETNVDFKKPKMYKVILLNDDYTTMDFVVEILITVF
                     HKTAADATRIMLDVHRKGKGVVGVYTYDIARSKIALVEKMAAEREFPLAAVMEPE"
     misc_feature    24675..24917
                     /locus_tag="ClothDRAFT_2355"
                     /note="ATP-dependent Clp protease adaptor protein ClpS;
                     Region: ClpS; cl00933"
                     /db_xref="CDD:186267"
     gene            24992..27322
                     /locus_tag="ClothDRAFT_2356"
     CDS             24992..27322
                     /locus_tag="ClothDRAFT_2356"
                     /inference="protein motif:TFAM:TIGR02639"
                     /note="KEGG: sat:SYN_02378 ATPase Clp protease ATP binding
                     subunit;
                     TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit
                     clpA;
                     PFAM: ATPase AAA-2 domain protein; AAA ATPase central
                     domain protein; Torsin; Clp domain protein; ATPase
                     associated with various cellular activities AAA_5;
                     SMART: AAA ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease, ATP-binding subunit
                     clpA"
                     /protein_id="ZP_05430495.1"
                     /db_xref="GI:256005534"
                     /db_xref="InterPro:IPR001270"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR003959"
                     /db_xref="InterPro:IPR004176"
                     /db_xref="InterPro:IPR010448"
                     /db_xref="InterPro:IPR011704"
                     /db_xref="InterPro:IPR013093"
                     /db_xref="InterPro:IPR013461"
                     /translation="MMRLDDVANKILIAAYNEAKHQKHEFFTPEHILYASLFFDEGRD
                     IIENCGGKVEDIKKDLLEFFRNNMPIVENHEPIESLGINSVMQATAYQCIAAGREYIR
                     IGDIIVALYGEKESFASYILQKNGIKKLDVLKYISHGVSLVPKNMETSLKSLETDTYL
                     EAYQYADDWEYDYEYEDIDEDEDIDEESSSKSNFLEHFTIDLTEKARKGKIDPLIGRE
                     DILERTIQVLSRRLKNNPIHVGDPGVGKTAITEGLARLIVEDKVPKSLKGSKIYYLDM
                     GSMLAGTKYRGDFEERIKKVLNEIQNQPKAIVYIDEIHTIVGAGAVSDGAMDASNIIK
                     PFLTQGTLRFIGSTTYEEYKKYFEKDRALSRRFQKIDVPEPSIDDTFKILKGLKDRYE
                     EYHKVKYTDSALRLAAELSAKYIQDRHLPDKAIDVIDETGAYVRLHAKDEDKVITIKN
                     KDIERTVSAIARIPIQSVSRDEISKLKNLDVKLKSTIFGQDKAIDTVVQAIKRSRAGF
                     NENEKPVASLLFVGPTGVGKTELAKQLSLHLGIPFIRFDMSEYQEKHTVSRLIGAPPG
                     YVGYEEGGLLTDAIRKTPHCVLLLDEIEKAHPDIYNVLLQVMDYAVLTDNNGKKADFR
                     NVILIMTSNAGAREVGRTLIGFDSRNVDRSAMTKEVERIFSPEFRNRLDDIVVFNHIN
                     EEMALLITKKAINQFKEKLKTKNIKLKVTERCCKWIAQKGLSSIYGAREILRYVQDKI
                     KTYFVDEVLFGELSKGGTAIIDVVDGEIKISKKTQR"
     misc_feature    25016..27280
                     /locus_tag="ClothDRAFT_2356"
                     /note="ATP-dependent Clp protease ATP-binding subunit
                     clpA; Region: ClpA; TIGR02639"
                     /db_xref="CDD:162958"
     misc_feature    25034..25180
                     /locus_tag="ClothDRAFT_2356"
                     /note="Clp amino terminal domain; Region: Clp_N;
                     pfam02861"
                     /db_xref="CDD:145814"
     misc_feature    25634..26116
                     /locus_tag="ClothDRAFT_2356"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes...; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    25709..25732
                     /locus_tag="ClothDRAFT_2356"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(25712..25735,25922..25924,26036..26038)
                     /locus_tag="ClothDRAFT_2356"
                     /note="ATP binding site; other site"
                     /db_xref="CDD:99707"
     misc_feature    25910..25927
                     /locus_tag="ClothDRAFT_2356"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    26087..26089
                     /locus_tag="ClothDRAFT_2356"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    26453..27028
                     /locus_tag="ClothDRAFT_2356"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes...; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    26555..26578
                     /locus_tag="ClothDRAFT_2356"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(26558..26581,26762..26764,26888..26890)
                     /locus_tag="ClothDRAFT_2356"
                     /note="ATP binding site; other site"
                     /db_xref="CDD:99707"
     misc_feature    26750..26767
                     /locus_tag="ClothDRAFT_2356"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    27002..27004
                     /locus_tag="ClothDRAFT_2356"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    27035..27295
                     /locus_tag="ClothDRAFT_2356"
                     /note="C-terminal, D2-small domain, of ClpB protein;
                     Region: ClpB_D2-small; pfam10431"
                     /db_xref="CDD:151009"
     gene            27329..28030
                     /locus_tag="ClothDRAFT_2357"
     CDS             27329..28030
                     /locus_tag="ClothDRAFT_2357"
                     /EC_number="2.3.2.6"
                     /inference="protein motif:TFAM:TIGR00667"
                     /note="KEGG: sfu:Sfum_0044 leucyltransferase;
                     TIGRFAM: leucyl/phenylalanyl-tRNA/protein transferase;
                     PFAM: leucyl/phenylalanyl-tRNA--protein transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA/protein transferase"
                     /protein_id="ZP_05430496.1"
                     /db_xref="GI:256005535"
                     /db_xref="InterPro:IPR004616"
                     /translation="MPVFRLTDKLVFPHPSLADEDGILAVGGDLSCERLLLAYKNGIF
                     PWFSEDEPILWWSPNPRCVLFPKDIKISRSMRKFLKKQLYEVTFDTCFRHVIAMCAKL
                     REGNTWITPEIIESYSKLHDLGFAHSVETWYEGRLVGGLYGVSLGKCFFGESMFSTMD
                     NASKTALITLCQKLEEKGFLLIDCQVYSKHLESLGAVNIDRDLFLKYLEAGLSHETLR
                     GNWKFFNEQKQVRNN"
     misc_feature    27344..27997
                     /locus_tag="ClothDRAFT_2357"
                     /note="Leucyl/phenylalanyl-tRNA protein transferase;
                     Region: Leu_Phe_trans; cl01006"
                     /db_xref="CDD:186298"
     gene            28071..29162
                     /locus_tag="ClothDRAFT_2358"
     CDS             28071..29162
                     /locus_tag="ClothDRAFT_2358"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430497.1"
                     /db_xref="GI:256005536"
                     /translation="MQKSIKNCFLSFLFPLAYLIQFLSSRASGLAEKIYSRGVYRIIA
                     RFLNLISGHIPVSIAEILVVLSILFALFYIVKTIIRMIKSSSKAFKILCNALVNILTA
                     VSLLYFGFMLLWGINYQRLPFSQIANYDTSPASTDELLEVCKSLMEHANRLRKHVEED
                     NNGVMKLSASVNETLKRACLGYEAASKTYPELHHNYGRPKGVILSEVMSYLGIGGVYF
                     PFTGEANVNISMPHTSIPFTACHEMAHQIGFAREDEANFIAYIACKNHPSPDFQYSGI
                     LSALINATNTLYRYNRDEYFKLRNSFSEGVIRDLDALNIYWEKYDTPIEDFSSSVNNT
                     YLKANMQQDGVRSYGRMVDLLIAEYRSRK"
     sig_peptide     28071..28154
                     /locus_tag="ClothDRAFT_2358"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 0.954) with cleavage site probability 0.832 at
                     residue 28"
     gene            complement(29183..30079)
                     /locus_tag="ClothDRAFT_2359"
     CDS             complement(29183..30079)
                     /locus_tag="ClothDRAFT_2359"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_05430498.1"
                     /db_xref="GI:256005537"
                     /translation="MKYLQEVFEFLGKHFLLALPMIIAVAIPNIITGTVNNAEILEGI
                     NELSSVAEYAQMDSMEMLRTYLEIMKPWFTASTIAGIVSFLLSLFVVPATYGMVNKGL
                     ETGNADLGDFFPQMAMNLPKFIIYKIFNFLVDTVLSLAFMLILALFIFLLWLLKEIGT
                     SVLFLGIAITFVVAVMLYVVIYGIKCILSYWYPAMLVDSMKVTSAFKKAVEVGRSCLW
                     QTVGITFLISMANFFITVTLKNFANTLPRVGIYLEPVLISIPSGLAGFILLAFYLAVY
                     RDKTRKMEDKDVDIFESPGEFV"
     gene            complement(30159..38927)
                     /locus_tag="ClothDRAFT_2360"
     CDS             complement(30159..38927)
                     /locus_tag="ClothDRAFT_2360"
                     /inference="protein motif:PFAM:PF06165"
                     /note="PFAM: glycosyltransferase 36; putative carbohydrate
                     binding; glycosyltransferase 36 associated;
                     KEGG: net:Neut_1665 glycosyltransferase 36"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase 36"
                     /protein_id="ZP_05430499.1"
                     /db_xref="GI:256005538"
                     /db_xref="InterPro:IPR009342"
                     /db_xref="InterPro:IPR010383"
                     /db_xref="InterPro:IPR010403"
                     /translation="MQMQLYILYLLGLFGILLCLFLLAIFSNCNERQRQLKVQDASLT
                     FDELEAYAKEIAIEHSVSGKKSMFSWPIPRMNDNYRYIMSVYKEMNEDVQKGISTTPA
                     AEWLLDNFYIIEEQVKSLRRDLTKEVYAKLPVLDSGHLKGYARIYSIALELLSHTDGR
                     IDEKVLVNYIKAYQSNNVLTGRELWAFPIMLKLVLIEKTRYICEKIAKAQEQRRKVEE
                     ILKAFDENIENTTQLITAIDNELKGKYEVNSAFIEYLAYKFRKMGRAYTHVLRYIDER
                     LGESGTTVDDITQKEHNEQTASKASIGNCIMSLKFISTVNWVDIFEQLSKVEQILRED
                     PSGFYSLMDFDSRNYYRNRVEKLALKYKVSESHVAKKAVELARNAVENGNLTDKRLAH
                     VGYYLVGKGICELEKEIGYEKSFNQRMFERIKEHPACLYFGFIGFITVLLLLCVTKYS
                     LFRAEKYGIALSIIAVLATIIPATDIAVNFVNWVLCKMIKPSLLPKLDFENGIPEEYA
                     TMVVIPALLPDENRARELIDNLEVYYLANREKNLYFSIAGDFKDAPNKEMAGDKKIIE
                     TALGRIAELNEKYGRKNEGGEKDSRDIFYYFHRHRQFNEKQNKWMGWERKRGALLEFN
                     EVLLGSRTTSYSIMSHDVSQLPKIKYVITLDADTILPLGAARKLIGTMAHPLHRPVID
                     EQKGIVTEGYGLLQPRIGFDIESVNKSLFSRIFAGEEGIDPYASAISDVYQDLFGEGI
                     FTGKGIYDLEVFQKLLKDAIPDNTVLSHDLLEGSYVRAGLVTDIEFIDGYPSKLNSYA
                     MRLHRWVRGDWQLLPWLRGKTKDRKGNVIKNPLSLISRWKILDNLRRSIVAPSITLLI
                     ALGFSILPGSSLFWLGASLLTIYFPLITGTIDYIASKPLGAITSKRYKPAICGLKASF
                     LQMTLQFVFLPYNAWLMVHAAVLSLVRVLFTKRNMLEWVTALDAERGLKNSLKGYVIK
                     MKAAAFQALVVVVLAFAFKTGFSAAVSVLPFAVWVSSPFIAYWISKETVYKTETLSDE
                     ENLELRRIARKTWRYYEEFVNRRNNYLAPDNFQEDPPNGIAYRTSPTNIGLGMLAALT
                     ARDLGYIGTLELCDIISRTMSTVEKMEKWNGHLYNWYDTRTLETLRPRYISTVDSGNF
                     VCYLITLKEGLAEYLNRPLEDRAFIDGIRDTASLIADENENPYKDISCLKECIVISEG
                     RSYVDIPQMMKALTKLSEDGNKMKDSKDVWKAKVDSMIEMLKIELYTYMPWCDMIDEL
                     TEAFEKSEADIKEAFHGIIRKLNSDYSLKAMPVVYRETIKQIEKLRKKLKDGQQKNIE
                     GLDRLKEALEGAAESADKLVKRYVDLINRICRIADETEFVHLYDKKKQLFSIGYNIEE
                     NSLTNSYYDLLASEARQTSYIAIARGEVDQQHWFKLGRTLTQIDRYKGMVSWSGTMFE
                     YFMPLLIMKSHKNTLLDETYSFVVRSQKKYGKQRNLPWGISESGFYSFDINLDYQYKA
                     FGVPWLGLKRGLVEDMVVSPYATMLVLPLVPRDAMDNLKRLIAEGAYGHYGMYEAIDY
                     TPERIPLGEKKGIVKSYMAHHQGMSILALNNYFNDNIMQKRFHADPVVDAAKLLLMEK
                     VPSNIVFTKENKEKILPFKDVVYDEKDFLRECGMPDPVLPKAHILSNGNYSVMVTDRG
                     TGYSRWKNLDVTRWREDVTLDNYGMFFYIRDVQNDEVWTSTFAPGRKKPDEYKVEFTS
                     GKAKYYRKDGDIDTLTEIVVCAGENAEIRSITLANHGQESCVMEITSYFEPVLSHHGA
                     DIAHPAFGNLFIRTEFLAEHNCLIAGRRPRSEKEKPVWIMNTVVLEGEGVGSLQYETD
                     RMQFIGRGRNVSEPVALEPHRPLTNSVGAVLDPVMSFRQIVRVEPGKSVKISFVTAVA
                     NSREDVVEMATKFKSPQVIKDELGMAVTKSRVEARYLNLDTEEIELYQDMISHILFIS
                     PLQRQKQKWVMNNKKGQPGLWPYGISGDIPIVLVMLDKTDDIDIVREVLKAHEYWRLK
                     KLAVDLVILNEEENSYTNPVNSLLMDIIAESHAHDLINKPGGVFILKKSNMPPEDIDL
                     ICSVSRIILKGDAGDLKDQVKYARSIALAEFKQFEKKPASYDSKLAKDLELNFYNGLG
                     GFGKDGKEYVIFLENGQNTPLPWINVISNQRFGFIVTESGSGYTWFENSRENKLTPWS
                     NDPVSDTPGEILYVMDEHAGDVWSVTPLPVREKEPYMIRHGFGYTVFSHASHGIEQEM
                     VQFVPVDDSVKISILKLKNQSQENRGLSLTYYIRPVLGVSDQFTAMHINTKADNGMIV
                     IKNNYNDEFPGRVAFIDSSLKVNSLTCDRKEFFGAGDIANPEGIKRTSLSGTTGAGFD
                     PCAAISVSVNLKPDEEKEIIFLLGAGRDEEEARQLSAKYKKLEEAKKALGEVKKFWEL
                     KLGALQFETPNTAMDILLNGWLLYQVVSCRLWTRSGFYQSGGAYGFRDQLQDSISLTH
                     IWPEATRNQILLHSRHQFIEGDVQHWWHEEKYKGTRTKFSDDLLWMPYATIEYIRITG
                     DYDILYEETPFLEDEPLKEFEDEAYRVPRISHTVSTLYDHCIRAINRSLKFGEHGIPL
                     IGSGDWNDGMNTVGNKGKGESVWLGWFLYSILKNFAPLCERMGDNELAKRYLDTADRI
                     VENIEKNAWDGKWYRRAYFDNGVPLGSIQNSECQIDSLAQSWAVISEGGDKERIAEAM
                     SALENYLVKRDEGLIKLLTPPFDEGDLEPGYIKSYVPGVRENGGQYTHAAAWVVMAFA
                     KMGDGEKAMELFDLLNPINHSRTHIEYSRYKVEPYVMAADVYSVPPHTGRGGWTWYTG
                     SAGWIYRVGFEYILGFKKRGETLEIDPCIPGKWTDFTIKYRYYDTDYIIEVKNPEGVN
                     TGVKKVIVDGKVCDDGKVQLVNDKDTHKVEVYMGKK"
     misc_feature    complement(34134..34778)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Uncharacterized protein conserved in bacteria
                     (DUF2329); Region: DUF2329; pfam10091"
                     /db_xref="CDD:150731"
     misc_feature    complement(33873..>33995)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Putative carbohydrate binding domain; Region:
                     CBM_X; pfam06204"
                     /db_xref="CDD:148044"
     misc_feature    complement(33534..33863)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Glycosyltransferase family 36; Region:
                     Glyco_transf_36; pfam06165"
                     /db_xref="CDD:148020"
     misc_feature    complement(33213..33476)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Glycosyltransferase 36 associated family; Region:
                     GT36_AF; pfam06205"
                     /db_xref="CDD:148045"
     misc_feature    complement(30162..33416)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Cellobiose phosphorylase [Carbohydrate transport
                     and metabolism]; Region: COG3459"
                     /db_xref="CDD:33262"
     misc_feature    complement(32346..32543)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Putative carbohydrate binding domain; Region:
                     CBM_X; pfam06204"
                     /db_xref="CDD:148044"
     misc_feature    complement(32025..32342)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Glycosyltransferase family 36; Region:
                     Glyco_transf_36; pfam06165"
                     /db_xref="CDD:148020"
     misc_feature    complement(31743..32009)
                     /locus_tag="ClothDRAFT_2360"
                     /note="Glycosyltransferase 36 associated family; Region:
                     GT36_AF; pfam06205"
                     /db_xref="CDD:148045"
     gene            complement(39141..39944)
                     /locus_tag="ClothDRAFT_2361"
     CDS             complement(39141..39944)
                     /locus_tag="ClothDRAFT_2361"
                     /inference="protein motif:TFAM:TIGR00186"
                     /note="TIGRFAM: RNA methyltransferase, TrmH family, group
                     3;
                     PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose
                     methyltransferase substrate binding;
                     KEGG: atc:AGR_C_593 rRNA methylase"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase, TrmH family, group 3"
                     /protein_id="ZP_05430500.1"
                     /db_xref="GI:256005539"
                     /db_xref="InterPro:IPR001537"
                     /db_xref="InterPro:IPR004441"
                     /db_xref="InterPro:IPR013123"
                     /translation="MNYITSAQNPIIKEVKSLKQKKYREEKKLFFIEGIRFVEEALKE
                     GVQIERILVSDKLAETNSGYEILKKVSNGGYPVFQLPHKLFMEISDTQNPQGILAVLS
                     MKNCDIEDVWDEKNFFVILDSVQDPGNMGTIIRTADAAGMTGVIVSKGCVDVYNPKVL
                     RSTMGSIFHIPICQSQDIFETMDRMKKRGIKICAAHLEGSCDYFDLEYKNNIAIVIGN
                     EANGISEEVKNFADILVRIPMPGRAESLNASVAAGILMYEILRKNIGKR"
     misc_feature    complement(39156..39935)
                     /locus_tag="ClothDRAFT_2361"
                     /note="rRNA methylases [Translation, ribosomal structure
                     and biogenesis]; Region: SpoU; COG0566"
                     /db_xref="CDD:30912"
     misc_feature    complement(39630..39854)
                     /locus_tag="ClothDRAFT_2361"
                     /note="RNA 2'-O ribose methyltransferase substrate
                     binding; Region: SpoU_sub_bind; pfam08032"
                     /db_xref="CDD:149230"
     misc_feature    complement(39174..39599)
                     /locus_tag="ClothDRAFT_2361"
                     /note="SpoU rRNA Methylase family; Region: SpoU_methylase;
                     cl00362"
                     /db_xref="CDD:185941"
     gene            complement(40091..40444)
                     /locus_tag="ClothDRAFT_2362"
     CDS             complement(40091..40444)
                     /locus_tag="ClothDRAFT_2362"
                     /inference="protein motif:TFAM:TIGR01032"
                     /note="TIGRFAM: ribosomal protein L20;
                     PFAM: ribosomal protein L20;
                     KEGG: pmy:Pmen_1979 50S ribosomal protein L20"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein L20"
                     /protein_id="ZP_05430501.1"
                     /db_xref="GI:256005540"
                     /db_xref="InterPro:IPR005812"
                     /db_xref="InterPro:IPR005813"
                     /translation="MSRVKGGVRTRARHKKILKLAKGYFGAKSKNFRIANQAVMKSLV
                     YAYRDRRARKRDFRKLWITRINAAARMNGLSYSKFMNGLKKSGIALNRKMLAEMAVND
                     AEAFAQLVEKVKAVI"
     misc_feature    complement(40100..40441)
                     /locus_tag="ClothDRAFT_2362"
                     /note="Ribosomal protein L20; Region: Ribosomal_L20;
                     cl00393"
                     /db_xref="CDD:185964"
     gene            complement(40463..40660)
                     /locus_tag="ClothDRAFT_2363"
     CDS             complement(40463..40660)
                     /locus_tag="ClothDRAFT_2363"
                     /inference="protein motif:TFAM:TIGR00001"
                     /note="TIGRFAM: ribosomal protein L35;
                     PFAM: ribosomal protein L35;
                     KEGG: sat:SYN_01719 50S ribosomal protein L35P"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein L35"
                     /protein_id="ZP_05430502.1"
                     /db_xref="GI:256005541"
                     /db_xref="InterPro:IPR001706"
                     /translation="MPKIKTHSSSKKRFKLTGTGKVKRAKAYKSHILTKKTSKRKRNL
                     RKSTIASSANASVIKKLIPYK"
     misc_feature    complement(40466..40660)
                     /locus_tag="ClothDRAFT_2363"
                     /note="Ribosomal protein L35; Region: Ribosomal_L35p;
                     cl00392"
                     /db_xref="CDD:185963"
     sig_peptide     complement(40481..40660)
                     /locus_tag="ClothDRAFT_2363"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probabilty 0.993) with cleavage site probability 0.603 at
                     residue 60"
     gene            complement(40686..41180)
                     /locus_tag="ClothDRAFT_2364"
     CDS             complement(40686..41180)
                     /locus_tag="ClothDRAFT_2364"
                     /inference="protein motif:TFAM:TIGR00168"
                     /note="TIGRFAM: translation initiation factor IF-3;
                     PFAM: initiation factor 3;
                     KEGG: lpp:lpp2769 translation initiation factor IF-3"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="ZP_05430503.1"
                     /db_xref="GI:256005542"
                     /db_xref="InterPro:IPR001288"
                     /translation="MINEQIRDKEVRLIDTDGTMLGIMSSKEAQKIANAKNLDLVKIA
                     PQAVPPVCRIMDYGKYMFELAKKEKEARKNQKVINVKEVRLSASIEEHDFNFKLKNAL
                     RFLKDGDKVKVSVKFRGREMNYTSLGQQVLEKFAEAVKDVAVVEKKPKLEGRNMFMIL
                     NPKQ"
     misc_feature    complement(40692..41180)
                     /locus_tag="ClothDRAFT_2364"
                     /note="translation initiation factor IF-3; Reviewed;
                     Region: infC; PRK00028"
                     /db_xref="CDD:178804"
     misc_feature    complement(40965..41180)
                     /locus_tag="ClothDRAFT_2364"
                     /note="Translation initiation factor IF-3, N-terminal
                     domain; Region: IF3_N; pfam05198"
                     /db_xref="CDD:147407"
     misc_feature    complement(40692..40952)
                     /locus_tag="ClothDRAFT_2364"
                     /note="Translation initiation factor IF-3, C-terminal
                     domain; Region: IF3_C; pfam00707"
                     /db_xref="CDD:144345"
     gene            complement(41452..41955)
                     /locus_tag="ClothDRAFT_2365"
     CDS             complement(41452..41955)
                     /locus_tag="ClothDRAFT_2365"
                     /inference="protein motif:PFAM:PF00186"
                     /note="PFAM: dihydrofolate reductase region;
                     KEGG: neu:NE0567 dihydrofolate reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase region"
                     /protein_id="ZP_05430504.1"
                     /db_xref="GI:256005543"
                     /db_xref="InterPro:IPR001796"
                     /translation="MKAIVAVDSNWGIGYKGNLLQRIPEDMRFFRQMTLNKVVVMGRK
                     TFESLPGKEPLKDRVNIILSKSENIEKDGIIICRSVDGLFLELKKYNSDDIFVIGGEE
                     VYTQLLPYCSEAHVTKFNGAYSADRYFPNLDEMEGWKLVCVGEPKEFNDIRYNRLKYV
                     NENPKVY"
     misc_feature    complement(41476..41955)
                     /locus_tag="ClothDRAFT_2365"
                     /note="Dihydrofolate reductase (DHFR). Reduces
                     7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH
                     as a cofactor. This is an essential step in the
                     biosynthesis of deoxythymidine phosphate since
                     5,6,7,8-tetrahydrofolate is required to regenerate
                     5,10-...; Region: DHFR; cd00209"
                     /db_xref="CDD:29264"
     misc_feature    complement(order(41605..41607,41644..41646,41662..41664,
                     41782..41784,41878..41880,41893..41895,41944..41946))
                     /locus_tag="ClothDRAFT_2365"
                     /note="folate binding site; other site"
                     /db_xref="CDD:29264"
     misc_feature    complement(order(41650..41661,41761..41763,41821..41829,
                     41917..41919,41938..41940))
                     /locus_tag="ClothDRAFT_2365"
                     /note="NADP+ binding site; other site"
                     /db_xref="CDD:29264"
     gene            complement(41969..42799)
                     /locus_tag="ClothDRAFT_2366"
     CDS             complement(41969..42799)
                     /locus_tag="ClothDRAFT_2366"
                     /EC_number="2.1.1.45"
                     /inference="protein motif:TFAM:TIGR03284"
                     /note="KEGG: mfa:Mfla_1050 thymidylate synthase;
                     TIGRFAM: thymidylate synthase;
                     PFAM: thymidylate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="ZP_05430505.1"
                     /db_xref="GI:256005544"
                     /db_xref="InterPro:IPR000398"
                     /translation="MSKADEIFIAMCKDILENGVSSEGEKVRARWADGTPAHTIKKFG
                     VVNRYDLSEEFPILTLRPTNLKAAIDELLWIWQKKSNNIKDLNSHIWDSWADENGSIG
                     KAYGYQLSIKHKYPEGEFDQVDRIIYDLKHNPYSRRIIANMYNHSDLHEMNLYPCAYS
                     ITFNVTGRKLNAILNQRSQDVLVANNWNVAQYAILVHMFAQVCDLEVGELVHVIADAH
                     IYDRHIPLVKELIQRTPYPAPKLWINPEKKDFYDFKVEDFVLEDYQAGPQIKNIPVAI
                     "
     misc_feature    complement(42116..42778)
                     /locus_tag="ClothDRAFT_2366"
                     /note="Thymidylate synthase and pyrimidine
                     hydroxymethylase: Thymidylate synthase (TS) and
                     deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs
                     that catalyze analogous alkylation of C5 of pyrimidine
                     nucleotides. Both enzymes are involved in the...; Region:
                     TS_Pyrimidine_HMase; cd00351"
                     /db_xref="CDD:58645"
     misc_feature    complement(order(42152..42157,42266..42271,42275..42277,
                     42302..42304,42314..42316,42320..42322,42362..42367,
                     42386..42391,42671..42673,42677..42679,42725..42727,
                     42740..42742))
                     /locus_tag="ClothDRAFT_2366"
                     /note="dimerization interface; other site"
                     /db_xref="CDD:58645"
     misc_feature    complement(order(42140..42142,42146..42148,42236..42241,
                     42260..42262,42266..42274,42326..42331,42485..42487,
                     42518..42520,42527..42529,42587..42589,42722..42724))
                     /locus_tag="ClothDRAFT_2366"
                     /note="active site"
                     /db_xref="CDD:58645"
ORIGIN      
        1 gctgtcgtcc aatcccagta tctttgccaa tgctgcagcc tcaaaactcc acaagccaac
       61 gtagccgggc tttttatgtg catttttcca gtctaaatcg ttatgtccct taatccattc
      121 tttctctaca tattgttgaa gccttttcga agctctttcc ttgtctttat catgcaatgc
      181 catttgtata atttcagccg tctttgcata tggatttttt ctctcatatc tgcttgtatt
      241 atgattccat cctatatcac aagcttttaa aagaaaatct agcagtgcgt cttctatttt
      301 ttgcttctct attgcacaag caagcctttt taaatctttt ttatccactt ccaaaagtat
      361 gcctagtgac accattctca aaacgtcaac ataccatggt tctgcattac cgacattttc
      421 caaatactct ataccgttta aataatcttc aattatttca ttcggatgac tacctaaaga
      481 gtatttagct ataagtattt ctgtattata cataaacatt cctctatatg tagcataaat
      541 tatgctttga ttgtcttttg gatatctttg tatgcccttt tccatatcat ctttcagcat
      601 aataatcttt ttttttcttt cacaaattgc ttccttgtca aattctattg tttctaacaa
      661 ataactttca ctgcataacg gatctctcat accatcatct ccttttcatt tgttatttat
      721 ggccagaatc caattatttc accattgctg tttagcctat acgtcgttac tttcccatct
      781 ttgccaaccc gtgataaaac tttttctact tgacctttgt ttaacactct tattatgtcc
      841 ttttggagtt ttctatctcc attaactgct tccaaaattc ttttaccacc atcctcaagg
      901 agccactcat ccgacatttg ctttatgcct ttcttcgttt tacataattg ggaagcatta
      961 aatcttgatt cgttaattac atatttaata tttgagtttg gattctcgtt tgaatatatt
     1021 ccatctatcc cttttacaat ttcatcattc gaatatgcca tagcactcat ttcccacgtt
     1081 ttaaatcata tcctttgtct tttacacttt gattgttaat aaaattatca ttcgcacgat
     1141 attttctgta attacccttt tgcttgttac tggcagttta caaatccaaa ttttcaaagg
     1201 tggttttaga aagttgtaaa ccttcatagg ttaatccgtt atcttaggct tttttcctca
     1261 accaccaaaa cactgccttt tgaatcaacc aacctgtttc ctggttgcag cttcatttct
     1321 ttaacgaaac ctgtatcttt tatatataag ttgcctctct ttttatagga cacaaacaca
     1381 gttatttccg taattcagta atcttcaata aatcagttta aattaaaacg agcggaatta
     1441 ccattatcgc ccgtattata taaaattcaa ttaacgtttt ttacatcgtt cactgaaata
     1501 atatcaaaat ccatcctcat tttaataatc tcaatcattc actataagac taaacttcct
     1561 ctatcttctc cacttctgtc aattttacct cgtacaatga atctattgct gcggttttcg
     1621 gtacgtatgc ataatactgc tggtcattgt ccacttcaaa gcttatcaac tttacttcct
     1681 ctttgcccca ataattatct atatcttcta tgtaatctac caaatcttcc ttataatcca
     1741 actgcaaaat atactccttc tctacaagca aaaacactat aatcgttccc aacatatttt
     1801 tggctttatt atcttcctcg tactccttaa catcaaacca gatttctctc aaattatact
     1861 tcttccaaaa ctcttcgtcg ctcaatgtat tgtagtctcc tatcacttca ttcacaaaac
     1921 tgtggaactt tgcaggtatt atttgctcca actccgggtt attcggtatt ccatatacta
     1981 ttgcctcttc ttccttggct tcctcttcaa ctggcacacc ataccagctt aaatcaaaac
     2041 tcattccatt tttataatgc gccaaatcat aagggtaatg gttgttatct ttcagtgcgc
     2101 tgtcgtccaa tcccagtatc tttgccaatg ctgcagcctc aaaactccac aagccaacgt
     2161 agccgggttc tttatgcgca tttttgaagt ccagatcatt atgtccttta atccattctt
     2221 tctctatata ttgttgtagc cttttcgaag ctttttccct gtctttatca tgcaatgcca
     2281 tttgtataat ttcagccgtc tttgcatatg gattttttct ctcatattca cttgtattat
     2341 gattccatcc tatatcacaa gcttttaaaa gaaaatccat cagtgcgtct tctttttttt
     2401 gcttctctat cacacaagca agccttttta aatcctgttt gtctacctct aaaagtatac
     2461 ctaacgatag catccacaaa aggtcaatat accatacttt ttcttcaccg acattttcca
     2521 aatactctat accgtttaaa taatcttcaa tcatttcatc cggatgacta cctaaagagt
     2581 atttggctgt aagcatttcc gtgttataca taaacatatg taaaaacgta gcataaatta
     2641 tgctttgatt atcccttgga tatctttgta tacctttttc catatcatct ttcagaataa
     2701 caatcttttt ttacttttac aaattccttc tttgtcatat tctattgttt ctaataaata
     2761 actttcactg cataacggat ctctcatacc atcatctcct tttcatttgt tatttatggc
     2821 cagaatccaa ttatttcacc attgctgttt aacctatacg tcgttacttt tccatccttg
     2881 ccaactcgtg ataaaacttt ttctactgca ccgttgttta atgcttctat tatatcatct
     2941 ttcagtcttc tatcaccatt aactgcttgt aaaattcttt taccttgttt ctcacggagc
     3001 cactcatccg acatttgttt tatgcctttt ttcgttttcc ccaattgtgc agtattaaac
     3061 tttgactcat caatcacata tttaatattt gaattaggat tcttgtttac atatatacca
     3121 tctatccctt ttgtgatttt atcatccggt gatgtcggaa ctttccctcc tatctgttcc
     3181 aaatcatatc ctacttcctt caattttgga ttatttataa gattatcatc cgctcgatat
     3241 tctccataat tacccttttg cttgttactg gcggtttcca aatccagatt ttcaaaggta
     3301 gttttaggat tataattcgc attatgtacc aatatccctt tattcccaac atgataagta
     3361 tgaaagtcat caactttaaa gttgtaaact ttcacaggtt taccagttat tttgagcttt
     3421 ttctcttcta ccaccaaaac attgcctttt gaatcaacca acttgtctcc gacttgcaga
     3481 ttcaccgctt caacaaagcc aacatctttt acataaaatg gatggtcaac ggttgttttg
     3541 attacttcgc ctccaattct caaatgcaaa agctccgttg tctctctcac atatgtctca
     3601 agcactgtct tctcggctac ttcaaaagtc tccggattcg ccgcaattac cttatctcct
     3661 accttgatat tctctatcgc aaccaagcct gccgctgtca ataccatcgt acccgcaaca
     3721 aagcacttca ttgtagatgc cgccccggca ctgaaaacag ccagcgcgtt tactgcaatc
     3781 tggaatccat tgtaaagtgc attggaatgc agcttccggt taaattcaac caatgcgttg
     3841 gatggatcaa acagcgatac tcccattgcc agcatgtcaa atccgtccat acccaacgaa
     3901 agggctgcag ttactttcga agtaacattt attgcttttc ctacagtgct catgcattgg
     3961 atgcctttcc ctgccgctgc tcccaaagca ccaagcccgg cacatgccgc tcctgtcacc
     4021 gctccggaaa ccgctccgct taaagcgcca tccgcaaatc cttctaggaa cgaacctcca
     4081 tttatcgccg ctgctattcc tccgactgct cctcctatca agcctccggc caatgctccc
     4141 cagaacgctc ctgccagtat aactcccaat actccctcct gtcagcgccg ctgctattcc
     4201 caatcctgtg ataactactg cggcagccac tattttggca attgatttcc aattctcttt
     4261 acaccattcg gcaacagctt tacagccgtc cttaaatttt tcctagccgc ttttttcatt
     4321 ttccggtttc aagtaataat actctttgta gaaattctct tttcgtttat tgataagttc
     4381 ggcaacctca ctgtcgacac gtactacttc cgatataaac tcctcggttt ctttacaaac
     4441 tgtatcaaga gaagtgactt tcttatcctg ggtttgggaa gatgcctgta tggagattat
     4501 tacatcatcc agattgcaca cacttctgtt aatattcaga gttttctttt tcaatgctga
     4561 caactcagac ttaagatcaa ttacagattt tttgacatct tttattaaac ccggcatttg
     4621 attaattttt ccggcatata acgttatagt tgccatttga tcacctgctg ctgcttacag
     4681 tagtttcatt ataattaaat tatttctact caaatagttc tatataattt ctatattatt
     4741 tagtaatata atattatttt ttcataaaaa aaacaagatg gcatattatt gtcatcataa
     4801 aatatataac aaaaacaact tacaacaatt atttacttct gcaattttac tagaaattag
     4861 aatatatttt attaaaaata aatttttcaa acagttccct cttagtttaa aaatttgtag
     4921 tgaacgttcc gctaattaac ttctaataat ttttcaaact tttaatcaat taattttaat
     4981 tataatgaca aaatgttaaa ttttaaataa aaaagagact ttgtctcaaa catttatcct
     5041 cttttgagac agtcccttat gtatcaataa ctggagccac caggcggact cgaaccgtcg
     5101 acccgcgcat tacgaatgcg ctgctctacc aactgagcta tggtggcatc agcatataca
     5161 cattattaaa cttacataaa aatattaatt ccaaaacttc attttgtcaa gaccaataac
     5221 ttctaatttt aataccttat ctcaatactc ttttggcaat ttccttaaca ttaaatttta
     5281 ctttttcctc atctatggtc ttaagctctc tgttttccat cacaatattg ccgtcaatta
     5341 ttaccgtgtc aacgtccgag ctttgcgcgg agtataccac ggccgaaaca gggtcgttaa
     5401 cagggcacag atgcgtcttg tccatatcta taaggataag gtccgccttc attccctttg
     5461 aaatttctcc aatctcgcct ccaaacccaa gtgcctttgc tccgtttacg gttgccatct
     5521 ttaatgcaca ggaagcacca atcaatgtgg gatccatgtg aacccctttg tgtatcagcg
     5581 ccgccaaatg catttcttca aacatgttaa gattattgtt gcttgcggca ccatcagttc
     5641 ccaaagccac attgataccg tttttgagca tatcatccac tttggctatt ccgctgccca
     5701 gctttaaatt gctggtgggg ttgtggatca catttacgcc cttatccctg attataccca
     5761 tatccccgtc ggacaaatgc acacagtggg cagcgattac cggaacgtca aaaatgccgg
     5821 tcttacagca aatttccgca ggactcatac catacttttt gttgctgtcc tcacactctt
     5881 tcaaagtctc ctgcacatgt atgtgaattc ctgtgttgat ctcttttgca acttccgccg
     5941 acatacgcag cgacggttcg tcaaaaagat aaaccgagtg aacttcaatg tacactttta
     6001 ttctaccgtt aaagctgttg tcccacttct taaaatattc aaaacaccga acggcatctt
     6061 ccacactttt atcgctgtct ttaagcggac ttctgcaaag atttgccctt atgcccgttt
     6121 ccgaaacagc ccttgccact tcttccatat gaagatacat gtcggcaaaa gtcgtagtgc
     6181 ctgattttat catctcggct attcccagca atgtacccca gtatatgtct tccggtgtaa
     6241 gtttctcttc cacgggaagt acattgccga aaagccagtc ttccaatgca aggtcgtttg
     6301 caaagttcct gagtattgtc atcccgctgt gggtgtgggc attcaccaaa cccggcataa
     6361 ccagttttcc ctttgcgtca ataatccggt cggccttaaa gtcttttaaa gcatcttctt
     6421 ttgtatctat aaaatcaata tatccatcct ttatgcccaa aaacgcaccc tgcaacacgt
     6481 catctgacgc attgcaggta attatgtcgg cattctttat cagtatgttc accgaaacaa
     6541 ttctcctttg cttatatgtc ctttgcttat atgcttataa cttttacagt tcatatccaa
     6601 agtttatccg ttccaaagct tgtttagcac cagctgtcaa gatatttttt ctgctcctcg
     6661 gtaagctcat ctattgtaat tccccaggat tcaagtttca ttaacgcaac ccttctgtca
     6721 atttcctcag gcacgtcaat cacctttttt ccaagccttg aatggttttc aagcacatat
     6781 tttgcactca gggcctgaag ggcaaaactc atgtccatga tttccgccgg atgtccgtct
     6841 ccggccgcaa ggtttaccag tcttccttcc gcaagaagat ttatccacct gccgtcctcc
     6901 atcatgtatc ccataatgtt tttgcgctgt tcttccttgc ggacagccat ttcttccaaa
     6961 tccttaacac ttacttccac atcaaaatgt ccggcgttgc atagtatggc gccgtccttc
     7021 attaccttga aatgttcacg gtgtatcacc ctgctgcagc cggttgcggt aataaacaaa
     7081 tcaccaatct ttgccgcctc catcatgggc ataaccttgt atccgtccat gacggcctcg
     7141 gcagctttta tcggatcaac ttcgcacaca ataacacttg cgcccaatcc cttggctctc
     7201 atggcaatac ccttgccgca ccatccgtaa cctaccacaa caacattttt tccggccacg
     7261 atgagattgg tggttctgtt tataccgtcc cacaccgact ggcctgtacc gtatcggtta
     7321 tcaaacaaat atttgcagta agcattgttt accgccacca tggggaattt caaggcacct
     7381 tctttttcca tagccttaag ccttataacc ccagtcgtgg tctcctcgca tccacccatg
     7441 acatcggaaa gaagctcagt tctttcggtg tgcagcagat gtacaaggtc gcctccgtca
     7501 tcaataacaa tgttcggcct gccatccaaa gcaagattca aatgttcctt atattctttt
     7561 tccgttgcat tgtaccatgc gtaaacatta agcccgtctt ccgcaagagc cgcggcaacg
     7621 tcatcctggg tggacagcgg attgcttccc gtaacggaaa cttgtccgcc gcctattgca
     7681 aaaagctttg caagatacgc cgtttttgcc tcgagatgca ccgataccgt aattcttatt
     7741 ccgtcaaaag gctttgtttt tgcgaactct tcctcaaggc ttcttaaaag cggcatattc
     7801 ttccttaccc aatttatttt ctgcctgccg gattttgcaa ggctgatatc acgaataaca
     7861 ctacccatat tttatacctc ccagacggat attactcttt taaccaaacg gacaaattta
     7921 ttttcggctt cttttgccgt tttcataacc tcttcatgag tcaaaggctg atccaaaatt
     7981 cccgccgcca tattggttat gcacgaaatt cccagaatat tcatattagc atgtcttgcc
     8041 gcaataacct ccggaaccgt ggacataccg acagcatcgg ctccaagtat tccaagcgcc
     8101 cttatctcgg caggtgtctc atacatgggc ccctgggtaa aagcatagac tccttctttg
     8161 acatccactc ccacatctga agctgctttt ttacaaattt caacaagctt cggattgtat
     8221 gccttgcaca tatccggaaa ccttaatccg aactcatcta tgtttttgcc tcttaaagga
     8281 gacggagcaa agaagcttat gtggtcttta ataatcataa gatctcccgg cctgaaactt
     8341 ctgtttatcc caccggaagc atttgtgaca ataagattgt ttattcccag cattttaaag
     8401 accctgacgg gaaaaacaat ctgcgataca tcatatcctt catagtgatg aaaacgccct
     8461 ttcatggcaa ttacgcgccg gttttccaaa attccgtata caaatttgcc ggcatgccct
     8521 tcaacggtag tcaccggaaa gttgggtacg tctttataat caatctcaac tttgttttca
     8581 atctcatccg ccaaaggtcc caaacccgaa ccaaggacaa tggcaatctc aggcgtttct
     8641 tttattatcc ttttgataaa tgaagccgtt tcccgtgcct tttcgtatat attgtccatt
     8701 ttcaacctcc tgggaaaata gtttttcata atattcattt tttaaaaaat tcattgtttt
     8761 atttactgcc aaaaattaaa ccgtgcataa ggatatagta ccatagtttg aaaccaaaag
     8821 acaagcttgc ttttccaaaa agatataaaa accggataaa aactattgtc ctgtaatttt
     8881 ttgtcttctt accaaaaata ttgcgccaaa aatgacaatt gaagcaagaa caataaccga
     8941 atttaaaaag aatacctgcc tgattccgat taaatcactt atcacaccgc cgcctgtact
     9001 tccaattatc ctggaaatac ccaaacctat gacggagttt accgtctgtc ctgaggcctt
     9061 caattcaggt ggcatctcat tattgatata tgttgccatg gagtaggcca aaacaatgaa
     9121 tataaaacca tggagaattt ggagtgcaag cactgcaaaa atattgttaa tcaatcccaa
     9181 acttgcccac cgtacaactg caacaaccgc tgcaccgaac agcgtaaact tgattcccaa
     9241 acgttttatt atcctgtcgc cgaaaacaag gaagattatt tcactcgccg agccgataaa
     9301 caccgccaat cccagaatgg tgttgtcagc acccatgttt ttatagtaaa tcggaaagaa
     9361 agtattataa aaacccatgg tagtatgaat aacaagtgta aatcccataa gcagcacaag
     9421 ttcgctgttt ttgaaaactt ctaaaatgga aagcttgttt ccgtccgatt gatgtccttt
     9481 taccgttggc attctaaata ctgtaatcaa agacataata cctatgacaa agcatataaa
     9541 gaaaatagcg ttgatatttt ttcttgtcaa tgcccctccg ataaatgcca tcaccgcata
     9601 tcccaatgca ccggcaagcc ttatcgggcc atacttccat tttgtgtcag taatatactc
     9661 caatgtaatc gcatcaccta tcggagtaat gggcgtttgg aaaaaggcat aaacaaccat
     9721 taccgcaaat atatagtaat agttgcccga gagacgaaac ataaaaatgg caatgctgct
     9781 gaaaagcacc aacattttca gcacattgtt tttggatttt gcccggtcac ttatgacacc
     9841 ccaaatgggc tgtgcaaaca ggccgacaaa cgaactgatt gaaagaaatg ttcctatatc
     9901 cgtattgtca tagcccagcc cttccaaata cacaggcata aacacgccaa ataccgcaag
     9961 gcccatataa aacaaggaat aaaacagaat aaaagagaac gggtatcttt ctgaacgttt
    10021 aagattatcc aaaatcatcc tgctccttaa ccttttttta aaaagtttac attagaatat
    10081 tttatacccg cttaaattcc atgtccagaa ttaaaaatgc aaataaaaaa caccaaaaaa
    10141 aagcagctct ttccgacttc agctttaaag ccggaaaaag ctcttttaac agattttacc
    10201 cgtccgttaa agtaactttt ttctgctcgt tgcatacaat aatttttttc ttattatcaa
    10261 ttaccgtgcc aagcataact tttccatccc aaagatcaac tatatgtttc atggtttcat
    10321 aagcatagct caattcaatt tccctgccgt catattcatg ttccaaaacc agtgtgttat
    10381 ctttttgaac ccattccgcc acttttatga caggaatacc ggcaagaccc acattgtttg
    10441 ctatcgtatc ccttattttt ttccagccct cttcatccga cacttccgtt acgatgtagc
    10501 tgttgccgat cttggcatat tcaaaaagat tcatttcctc acaaagctcc cgggtaagat
    10561 accttcttat aaatgactgg tccctttcaa cttcccttac ctcaaatatt ttcttcggat
    10621 catcttcata tcttttcttc aggtcttcaa atattctaaa tccgatataa tatggattta
    10681 actgtcccaa aacgggcctt ataacctgat tgtgcctttt taaaaactca aaatgaagtc
    10741 cctgttcaag gtttagtttg tttaaaatgt tgtaatgcca aaagcttgcc catccttcat
    10801 tcattatctt ggtttcaatc tgaggaagaa aatacagcgt ttcctccctg acaatgctta
    10861 aaatatcgcg ctcccaatct gtgagcttgc tgtaattcat aaaaaataaa agcatatctt
    10921 cctcaggttc aacaggaatt ttcttaaaat ccgggggcgc ttcctcttct ttggacttag
    10981 gttccaaaag aggatattcg cttttaggct tattgtatct ttcaagcagc tccttctttt
    11041 tttcttcctg ggacagcacc ctaacgccga tattacggga tatctgatac ctaatggcat
    11101 gggcggcgtt aagtattttt tccaccttgg cataacctat tcccggatcc tgtatatact
    11161 cgcggattct gtcagcatgg tttttaaaca tatccaccgt gtctttggcc cttgtgccaa
    11221 gtttaaaaag ccggttgttt ttgaaaaagt cgttgtgacc gtaaacgtgt gccattgtca
    11281 atatctgcaa aagcagcgta ttgtccttca taaggtaagc tatgcacgga tccgagttta
    11341 taaccatctc ataaggcaat ccggtcaaat tgtatttgta aagagttttg attctctcat
    11401 agttctttcc atagctccaa tgagggtagt gcgaaggcat gcctacataa gtctcataag
    11461 caatcatatc ctcatagcta catatttcaa attcctgttc atagtagtca aggccttcgg
    11521 cacgggctat ctcttctatt ttttcgttcc attcaataag ttctttcatg ctgtattcgg
    11581 ccattatctc acccccattt gccccgttat tctccttcct tttccaggag tttcttcaat
    11641 cctggaagca catcatcttt attggttatt gttatgacag aaaaattgtc tcttttaatg
    11701 cttttttgaa actcgtcttt tatagtactt ccggtggaat aataacccgg cactatttca
    11761 ccgtatccaa acaggttgca cacatcacag agtttcaatc caagttcgac ggctttttta
    11821 ttgtcctcgg accagttgtc gccgtcactg caatgaaaag catatatatt ccaactgttg
    11881 gggttgtatc tctgctcgat tatttcaaga gctttttcat agccgctgct gatatatgtt
    11941 cctcccgatt cgcctctgtg aaaaaattca tcttcactga cttctttcgc agtggtggta
    12001 tgggctataa aaacaacatc aacattggca tatttcaatc ttataaactg gtacagcaaa
    12061 aaataaaagc ttcgggcaag atacttcttt gtctggtcca tggaaccgga aacatccata
    12121 atacagataa ccactgcatt gaaatctttt ttgcggtcct ctctgaccct tctgtatcgc
    12181 aaatcatcct cgctgaaagg aaatctcttt ctgacaccgt ccaaggtctc ctgcgcggcg
    12241 atatcctctt cggcactttc gtccaaatcg cccaattctc tgctgtttct cagatatgcc
    12301 tgctttcttt ttatcttttc aataacggaa cgcttcttgg caagtcttgg gggtattcct
    12361 tttcgctgat aacccaggtt cttgtagctt cttatggatt cctgctccgc aatcctcttt
    12421 ttatctatat ccggaagatt caaatcatca aagagataat ttatgagttc ctcaattgta
    12481 atttctgtct cataaatttc ttccccttcc tggtttccgg cctgcccaac tccctgtccg
    12541 ccgttagccg ttttctcctc gcctattttt tccccgcgct tttccgttcc gtctccggaa
    12601 cccaccgaag gaccgttttt cccgtataca aactgatatt ctttaatgct tcttatcggt
    12661 atttttattt ttttgtcctt gctctgaccg ataatacttt cctctgcaat gatattacct
    12721 atattctttt ttatggattc ttcaaccaat tccctgtggc gccgcctgtc ttcagcagct
    12781 ctgtcttttc cgccgctcac atattctctg aaaatagcca catcaatcac cccccggttt
    12841 gatttttgcg ggattaaggg gtttaatcct tccacaagtt gttagccgca tatttcaata
    12901 taacattgca gcaatggtcg cagtatccgt tatttttcat ctcctgaacc attgtatcgt
    12961 atttttcgct ctgctctttg tcccttacct ttgcctgtgt aataaccctg ctaagttctc
    13021 tgaccgatga tgtaagtttc ttttcaatag cttccttcaa aggctcatag ctggtatagt
    13081 caagctttcc gccgtttctc aaaacataga acatatatgc cgtaacatcc gctctaaatc
    13141 cctttgccgc agtatccgta attcctatct gctcctctat ggatcttagg aatttttcgt
    13201 ccggctcaag ctcttctccc gtattcctgt cctttatctt tgacttgttt acaaaggcct
    13261 cggcatggtc aagatagttg ttaaagaggc tttccgcctg ttccttgtag ccatgaataa
    13321 acgcctttgt aatttctctt tccaaaatct tgttgtattc ttttcttata ctgtcctgca
    13381 caaaccttaa atatctttcc ctttcttcct cgctgattga cagctccttt attgatttaa
    13441 ccagtgtctc cataacagat atggggttga tgcagttgtg ttccgattct gaaagcgtcg
    13501 tatccagcac tttcatgata aatctcgtgg aaatacccgt cattccttcc ctcggagcct
    13561 cttctttaag ttcaaaaata tcaactttct ttgtcatacc cttttcaatt atttcctcac
    13621 cgttgtatat cttaagcttg gtcatggggt ccaccttgtt tgacggggca agccttgtca
    13681 gtattgcaaa cattgcagca atttcaatgg tgtgaggtgc tatgtgggca tcgaacttgc
    13741 tctttctcaa tattttttca taaattttta tctcttcgtt aagctccaga caatacggaa
    13801 cttcgatttt tacaattcgg tcaagtattg cttcgtttgt gtgatcggac ttgaacttgt
    13861 tccattccgc ctcattagaa tgggccagaa ttataccgtc aaagtatatc attgaacctt
    13921 ttccgggaga cggaatcgac ttttcctggg ttgcggtaat cattgtgtgc aaatactcgg
    13981 tctcattttt aaacacttca atgaactcaa caataccgcg gtttccgaca ttgaacgcac
    14041 cgttcagcga aagaactctg gggtcatctt ccggatacaa gtctatcttg gatatgtcca
    14101 cgctgcctat aagaaccgat gtgtcctggt tgttgggatc cacgggaggt accacaccga
    14161 tacctttcct tgacctgatg gaaaaatcca ccgtctcaac gggaaatctc tcatattccc
    14221 cattatattc gtttttaagt ctgtaacggc atatggggca caggtctcct tctatcctca
    14281 cattcaatat ttcttcaaat tcttttctca aatgttttgg cacaagatgc aaaggctcct
    14341 ccctcattgg gcatcccttt aatgcataaa tcggaggact catttccaat gcgcgtttta
    14401 aagcttccat caatgatgat tttcccgcac cgaccggtcc caccaggtaa agtacctgtc
    14461 ttgcttcttc tcccgccatg gcagccgaat gaaaatacct tacgattttc atgattgtct
    14521 tatctattcc gaaaaattca tcctcaaaaa atttatattt ctttataata tcatttccat
    14581 atatcctgcg aagtctggga ttttcctcgg ttcttattac ggtcacaccg ggttccgtga
    14641 taagcttata cattctttgg tgagcaagca tcgtaatctc ggggttttct ttcacaattt
    14701 caaggtactc aaggaaagtt ccttcaaact ttttgctctt gtgttcttcc ctgtccttgc
    14761 gtatgatact tgaaaaatcc agtctttcca tacttcattc cccctctttt tgtggaatat
    14821 tcgttaaaaa atgttaccaa atgtgcagcc aatccttttt caaactttta aagcttgatg
    14881 acatcgccaa aacctaaata taaaaaaatt agaattttgg ggatattacc ttattccggt
    14941 tgactcatgc ataagtttca tattttcata tatattaccg agtcagtcat aaaatactgt
    15001 cattaaatat tgttagaata ttgttaccca gaactgattt acctgaaacg tcaaactcaa
    15061 attctgtcgc tctaaatgta aaaagccaaa ctctgacata gaaactatag aattgcttac
    15121 tttaattata acataacagc atgttaatag ccatattttt tgtatggaaa gcatggaaaa
    15181 atatctttat gacattttct tttttatgat ataatgaatt tattcagtac tatgtttaca
    15241 gggatttata gaacccagct ttatgtagat tcctgtataa aggagttgac attttttatg
    15301 aagttcaaga ttcccaaatt ggactacaaa tctattatca tctggtccgt tattctaatc
    15361 gcaggttttt ggtatctaac gagaggaatc agtcatgaaa ctctctggta cgatgaatct
    15421 tattcggccg ccattatcaa ccattcaata cctgatataa tcagaattac tgcaaacgac
    15481 agtcacccgc ctttatattt tataatgctc aaaattttca gttctgtgtt tggacgcact
    15541 gaatcggcac taagactttt ttcggtattg ggattgctgg ctttggcaac tcttggcgca
    15601 ggtccggtaa gacgggtgtt tggcaaattc atgggtatga tgtattcatt ctgtgtaatt
    15661 gccgtcccca taagcctgtc aataggccag gaaacaagga tgtacacatg ggcggctttt
    15721 tttgtcacag ccggcgcttt gtacggatat cttgcattgc aggaaaacaa aaggtccgat
    15781 tggattaagt ttggactggc caccctggca tccgctttta ctcattatta cgcactgctt
    15841 gccgttactg ttttaaatgt actgctcttt gtctggctgc ttttaagatt cataaccacc
    15901 aaagataaaa agaagtttac aagttactta attactgcag gagctgtagt actgtgctat
    15961 tttccgtgga tttttatatt attcggtcaa gcaaaaaagg tttccaaatc tttctggata
    16021 ccgcccgtca cgaaagatgt catctggtat actttacagt atccctttgc agccaagttc
    16081 tggacattta gattctcaag agtatgtttt atctgtgcag tcgtactcat actatgggga
    16141 ttgatattct cggtaataaa acgcaaaaag caagggttaa tgtctttgct tgcagtgttg
    16201 atatatactt tgaccctggt aagtgcaatt gttctttcca atgtaataag gcctcttttg
    16261 gtggaaagat acatattccc ggttgtcgga ctgtttgttc tggcctttgc atacggaata
    16321 tccatgctca acagcaaagg tgcttcaata ttcgtttgcg tggcattatt ggccgtttca
    16381 atttcgcaaa accagttgat tatcgagaaa agatttaacg gtccgatgaa agaagtatgc
    16441 agttatatca atagccagaa tataactccg gaagacgttt ttattcacac agatgaacat
    16501 acatttggaa cattttgtta ttattatccc aacaacaagc attatcttta ccttcctccc
    16561 gacttcgacg gatacagcgg atatgatgct ttttcacctg ccggctccta cggttcggac
    16621 atcaaagaat ttatagacgg ccgggaaaaa atatggtttg tggaacgtga aggatccgac
    16681 atgagtaaac aagggtccaa attgctcgat aaacatattt tgcaaagcag aggcatgatt
    16741 cttaagttca acctttaccc gcattctttc tacgctgtta ctttaaggag ggttgttccc
    16801 ggaaatgcat taaaagatta agccggtgaa aatttaacat ggcttaaaat tgccgccgct
    16861 tactgcaaga gctgcaggaa gtggcggatt tattgaatcc gcagctcttt tttcatatat
    16921 ctcgatcaag atatatttac tttgcagata ctcaatcaat tcttttccct attttttctc
    16981 ttttctttct tttaatttta aaaactctac aaaatgaatt acttctttct tcttttcttc
    17041 tgatagttgt tcaaaatcat taataagttt ctctaccaaa ctcatttttc cttcaccctc
    17101 atacaaatat tttacatttc ataaacatat ttatatattt cttgattttg ccccttgtaa
    17161 tccccaaaac acttttcttt taaactgaag gaacactttt ccaaaaccct gcaggaagca
    17221 atattatctc cacggcaaat tccccaaata cgtttaatat taagccgctt cattatcagc
    17281 ggcacaaaag cctttaccgc ttctgttgca taaccattac ccgtatattt tgacgcaata
    17341 tgatatccca cttcccattc atcaccaatt ggaactgcct gcacataacc tatattctca
    17401 tggacaattt cagccatact cacattaaat tcagtaatta tcaacctatc tgttattatt
    17461 tttaatgtat ccattataaa atcttctcct ttagcaaatc agatagtcaa agctttttat
    17521 acccaattat ataaatccat tatacaaatt gttaccataa tatacaagta agcaaagcat
    17581 aaacagcaac taaacagcca tattttcccg aatcaattcc agctgcttta atgatataat
    17641 attgtacagg taataattat aatagataca accatcacta tttcattata aggaggatgt
    17701 catgaacaac ttgtacaaat acacaaaaaa catcgcttta tttataacat cctctcttgc
    17761 gggaatcata ctctttgtct ggattatgtc aataaacctt ggcacctccg ttatgacatc
    17821 cggttttcat aagaaactac tcgaaaaaaa caatatttac gatgaagttc aaaatgaaat
    17881 taataatctg gtacagagca tatttactga cttaagcagg cagctgccgc agcttggcga
    17941 ccaacaagag gaaatacttg caatactcga aggttccatt tcgcctcaaa tggtcaaaac
    18001 aaacctcgat acaatcgccg acggcctgtt caaatacttc aacggcgaaa aaagcttttt
    18061 gcccgatatt attattgaca ccgacccaac atctttgcaa agttcaaacg cggcagaagg
    18121 ggactcttcg gaagatactt cagacattac aaattccgaa tacgtattaa gcaaaataaa
    18181 aagagtcaat ctcaatgcaa tacttttgtc tataaatcgc agtgatattt tggatatgct
    18241 tctttttata aagctgattt atttcatcat ggattttgca ccggtatttt gcgctctgct
    18301 tctgttactg ctgtttttaa aatcactgct gcttggcaaa aatataaaag aaatgctaaa
    18361 ttggcttttt agagtattaa tgacctgcag catcctgtgc attataacgg caatattttg
    18421 cctggtatat tcctacaaaa tccttcccgg gaatatatat atgctctctg tagccatccc
    18481 tctgaaatcc gaagtacttc tgtcctatat ccgggactgt tttgtcccgt tatttgtatt
    18541 tttcacggcc tcaggaatcc taatggtgtt actggccttt ttggttgtgt cacttaacaa
    18601 ggttgcgaat aaattcagct ctgtaaatat aaatatattt aaatttaaaa acttttcaat
    18661 caaacacaaa aaaatattaa aatatacaac cattatgctg ttattgattt tttccctttc
    18721 acttttttgc tttgaactgt actcctttaa aaaagagttt gaatccaata atttttccaa
    18781 cttgatatca agactgacca attcaaactc ttatacagaa gtaatatccg caaaagatga
    18841 tacaatttat atgcttcaga ttaaacttgt tgacgccaaa gacaactctc cgattttggg
    18901 tattcaaata aatgtaaacg gcaaaacgga caatcccgaa aagtactaca acatcgcagg
    18961 cgaaaccgat gaaaccggca ccgttaaatt cacactggga aagggaacct ttcacctggc
    19021 attttctccg gcggaaggaa gcaccgatta cattctgccg tctccatttt tctatgaact
    19081 aaaatcagtg ggaacaacca tgcttacagt gaatctcagc aaaaaccagg cattgaccca
    19141 aagcaccgga attacggaaa tcgaagtcct ggacgaaaac aaccatcctg tagagggcat
    19201 tgaactttat gttgacagtg aaaaaaactc acctcaacat cctgaaccta ctccatctgc
    19261 cgatgtgtta cattctgcat cctcaaaaaa cccagaacca tccggtaatc ccgacaggtt
    19321 tttctcagtg accaacgaag aaggcattgc tgtattcaaa ctcccttccg gtatatacaa
    19381 tgtaaaattc tctccggaca agctccctaa agattacaaa gccccggaac tttttgaaat
    19441 caattgttct cccaatctta caacaagata tacaatacgt ctggttaaat ctccccggta
    19501 attaaagtaa cataattctg cttttcagaa tattatgtat agcaggtaga catatttaat
    19561 atgaaaagga gaattattat ggattactac tattatcctt ttgtatccga tccctacgct
    19621 gtatatacac caaatgtgtg gcaatctcag ggagccgatg aattatattt gtattccatg
    19681 cctgctatag aaagacaacc ccaaccggta ttaagcaacg cacctgcaca gacctccatt
    19741 gtacttttta aagaacttac cggatatcca aactacggaa atcccagcgg taacgcagac
    19801 attttatata ctggcaaccg tggaacatgg acatttgaca tacagcccat tttactcata
    19861 ccgggcaacc ttactgcaca gctggtaata aggggagttc ttgatgacca cacaaatgtt
    19921 cctgtggcaa actattccgc cagaataaca ataaacggca ccgtcgttca tacaggaaga
    19981 cttcctttgg ttcacggctc accggcgggc cagcgtttca acaactggag gcttcttacc
    20041 tttaatgtgc cgaatcttag aagaaacaac acagttgtaa ttcaaaatac ttcaaacaca
    20101 ggtccaaatg actggattgc ctttgactgg atggaattga ggcttcagcc aaggtagtat
    20161 ggtgagaaaa cttttgtttt tcaaaacaac ctaaagtaaa acccccacat ctaaaataaa
    20221 ccctgttttc ttcgaaaaca gggtttattt tcaaaacttt atttaaattt tcctcacaat
    20281 cagagtttat taattcaaag tttattagtc aacctttggc aaatttttca tacttcttgc
    20341 aatttcctct tccgaataat ccacgtcact aagttttccg ctaaagtagt tgtcataagc
    20401 ggccatgtca aaatatccgt gtccactcaa attaaacaga ataactttcg cctctcccga
    20461 ttctttgcac aacagggctt cgtcaatagc agcccttatt gcatgggaag actcaggagc
    20521 gggaacaatt ccttccgttc ttgcaaaaat aacagccgct tcaaaaaccg aactctgtcc
    20581 gtaagctttt gcttcaatca acttatcctc ataaagctgg ctgactattg gtgaaactcc
    20641 gtgatatctc aacccgcctg catggatacc ggcaggtaca aagtcatgac caaccgtata
    20701 catctttgcc aacggaccga tctttcccgt gtcggaataa tcataagcat acacaccttt
    20761 tgtgagagtg gggcatgcag tcggttcaac agccactgct ctcacttttg ttcccttaaa
    20821 cttgtccatc aggaacggaa aagctattcc ggcaaagttt gatcctccgc cgcagcaggc
    20881 aaagaccaca tcagggtatt catccagata ttccaactgc ttcttggcct caagaccgat
    20941 aatggtctga tgcaaacata cgtgatttaa aacacttccc aaggcataat tggtatcatc
    21001 gtgcgtagcc gcatcttcaa cagcttcact tatcgcaata ccgagacttc cggtacaatc
    21061 aggatctttt tccaaaatcg ccctgccgct gcttgtaaga ttggtaggac ttgcatacac
    21121 ctgggctccg aaagttttca tgaaagaacg tctgtagggc ttttgctcat aacttacctt
    21181 aaccatgtaa accgtacact caagtccgaa atgattgcat gcaaggctca gtgcacttcc
    21241 ccactgtcct gcgccggtct ccgttgaaag tctttttatg ccggcaatct tgttgtaata
    21301 agcctgcggc aatgaagtgt taagcttgtg gcttccggtt gcgttcgttc cttcatattt
    21361 gtaatagatt ctggcaggag tccccaaatg cttttccaga gccctagccc tgtacaacgg
    21421 actcggtctc cattgacggt acatttctct tacttcttcc ggaatgtcaa tccatctctc
    21481 ctgggaattt tcctgttgaa tcagttccat cgggaaaatt gcctgaagtt cgtccaacgt
    21541 aaccggtttg ccggtttttg agctgaagta aggtgcgggc ttgttgggca tgtctgccaa
    21601 aatattgtac cattgctttg gaatatccga ctcatctaaa actaccttgg ttacatcttt
    21661 tttactcatc tttctctact ctcctcacaa aataatacca ttaactaata ttgtactaga
    21721 aaaagccgcg acaatcaaca taattacaaa atttatcaat gaattctctg taaaaaacac
    21781 actctgacag ttttcaggcg taaaaaaagc gcatccaatt acactcagac gcactaatac
    21841 atagttatcg ccctatttgt caaattacat gcctttttta cgggccaaat ttatatattt
    21901 tttaatgttt accccaaaaa cttatccccc tgaaatttag attttgcatc tcattacgca
    21961 cactctcttg cttccgatct cctgccaata ttctatataa tcatcgtcct gcttaaagtt
    22021 ttcgaaggca taaccttttg actttacata ttccacaata tctagggaga aaagaacatc
    22081 caatgccgct tcacttaaat ttggcaattt tcttaaggta aactcgtcgc acaagttctt
    22141 aaactggtca aaaagcaata tggtgtatgt cttttcattg tttttgtata gtgcatagcc
    22201 cggacgcact ctgacaatgt cctcaacggc aatttttctt tcttccagca gcaaatcgct
    22261 aagtttcttt tcaagataaa ggattttgca attttcaaga tatttgagca actcatcttc
    22321 cttgaaagct ttgactttat ccaaatttat cgtaagaaaa tccggtttct cgtttttaaa
    22381 aagaaccagg gttgctacat ctttgtcacg ataccatatc tcgccgtcat tcatgtatat
    22441 gatatcaccg ttcaaattct tttcattgaa caccgggaac aagtaaggat aatctttgaa
    22501 aaacttaacc atcctgagaa ataccttgtt tccttccttt atggtaaccg tacacgggtc
    22561 tccccacata tccctgtcta ccacaaccat tcttccggcc tctgtaatat aaatataatt
    22621 cttcttgtcg gcctttttca aatctctttt tgtaacatcc aaaagtcttt caagatttct
    22681 tatcttgtct ttcttcagtg aattaataaa gctggtcgct ctctctcttc tttcatgaat
    22741 attttccact atgctatcct ttaagtttga cagaatctcc ttgctttgat ctactgagat
    22801 ttttgacgtt atagtttcca tgagattttt gacaccttca ttaccggtgc tcaatacttc
    22861 ttttttatta tccatgaaac accacccctt tatataaacg aacgagaaac agataagaag
    22921 agaacgatta ttgcaaagag taatgtattt tatagttata atttatgcga agtatattaa
    22981 tattattatt tttattatac cctataacac aaaaaatgcc aagcccttaa tccataaata
    23041 tttaatatta ttatatttaa acaaatcgta tataattttt ttgttcatat atatcccacc
    23101 caaaaatttt tgataaaatt atatgggaaa attaaaacaa cttggaatta tcatcacaca
    23161 aaagaggagg aacattaatg aaaaacagcg ttaaagcaaa aatatcagcc tttattatct
    23221 caatattaca tggtcaaact ggaagaaagc ttgggcagca ttgaaaaagt ccttgacgaa
    23281 taccttcttt cattgcaggt tgatattgat tttgacaaat acttcacaga taaaaagtca
    23341 tacaacaaac ttcgaaaaga aaagctttta aaaaatggat gaaagcagta ttattaccgt
    23401 agaagaaatt gaaagaaagt actttgaaac cctgcaaaaa ttcaacgatt acctaaataa
    23461 cagcaataat aattctcctg atacggatgt gggaaacaat taaaaaaata aaagtcaatg
    23521 caaaccggac agggtagggt aggcaagtta agctctcccg ccctgttttt ttgtttcctt
    23581 tttgtccttt cttaccattt cataaaaacc cagtatcaaa agaaacatcc caaaatatct
    23641 tttcagcgac gctccggata acgacactgc caatttagaa cccaaaaacg caccgacaag
    23701 cccaaagatg acaatgggaa tcgtcagctt aaagttaacc cttttattct ttatatgtac
    23761 aataagggct attaccgccg tcggtataaa aaataaaagg ttcacacttt gggcaatgtg
    23821 ttggtccgga ttgacaaaga ataccaaagc cggaataaga attgctccgc ctcctattcc
    23881 cattccgctg attattcccg aagcaagtcc tatcaaaaaa agaaccattt gtcctcctcg
    23941 ttgctttatt actttcgtta tattatcatt ctcacagccg ccgctattat aaatactgca
    24001 aaaatttttc ttaaaacatg ggaaggacag acgttaagaa gctttgcccc caaatatcct
    24061 cccacaatcc ctcccagcat ggttttcacc gtcaaattcc agtcaatata gctgtttgaa
    24121 acataaataa aggcacttac caaagttaac ggcaaaataa tcgatatggc agtggcatgg
    24181 gccacatgct cttcttcttt caaaagcaaa accatggcag gaacaacaat tgttcctccc
    24241 ccggaaccga aaagaccgtt tgcaatgcct gtgacaagcc cgattaccgc aaatttgaga
    24301 tattgggata ttggaatttt acctttcaaa aaaaccactc cgaaacaaag ttgtccataa
    24361 cattattctt ggttaatttc aaatatatat tccacatttt aattaaattc tataactttc
    24421 catgaattat aaaccgatag ctgttgtatt gaagcagttg gatttgttat aattctattg
    24481 tatatagata gttatatctg tatgttatat ataaattggt tatatatatt aaatataaac
    24541 tggttatata ttaaaagagt gcaaaattta ccgaaagatt tattaagaga tattcaaaag
    24601 caatctttaa acgatgggag ttgcttttta tgtctgaaaa gacgatagtt aaaaaagaaa
    24661 ccaatgttga ctttaaaaag cccaaaatgt ataaagtaat ccttcttaat gacgactata
    24721 caacaatgga ttttgttgtt gaaatactta taacggtttt tcataagact gccgccgatg
    24781 ccacaagaat catgcttgat gtgcatcgta aaggaaaagg agttgtggga gtttatacat
    24841 atgacattgc cagaagcaaa atagctttgg tggaaaaaat ggcagcggaa agagaattcc
    24901 cacttgcagc tgttatggag ccggaataat tttttgtatt tcttacataa gcaaaaaatg
    24961 atttttgtat ctgtaaaggg acggtgactc catgatgaga ttggatgacg tagctaacaa
    25021 aatcttaatt gcagcatata acgaagcaaa acatcaaaaa catgaatttt tcacaccgga
    25081 gcatattctt tatgcttccc tgttttttga tgaaggcagg gacataatag aaaactgcgg
    25141 cggcaaagtt gaagatatta aaaaggattt gctggaattt ttccgcaaca atatgcccat
    25201 tgttgaaaac cacgagccca tagaatccct ggggatcaac agtgtcatgc aggccactgc
    25261 gtatcagtgc attgccgcag gcagagaata tatacgcata ggcgatatta tagtggccct
    25321 ctacggtgaa aaagaatctt ttgccagtta tatacttcaa aaaaacggaa taaaaaaact
    25381 tgacgtttta aaatatattt cccacggagt atccctggtc ccaaaaaata tggaaacatc
    25441 tttaaaatct ttggagaccg acacttatct tgaagcttac cagtatgccg atgattggga
    25501 atacgattat gaatatgaag atattgatga agatgaagac attgatgaag aaagctcctc
    25561 aaaaagcaac tttttggagc actttacaat tgaccttacc gaaaaagcaa gaaagggtaa
    25621 aatagaccct cttatcggca gagaggatat tttggaacga acaatacagg ttttgtccag
    25681 aaggcttaag aacaacccca ttcacgttgg ggatcccgga gtgggaaaaa ctgcaattac
    25741 cgaaggtctg gcaaggctga ttgtggagga caaggttcca aaaagtttaa aaggcagtaa
    25801 aatatactat cttgacatgg gaagcatgct ggcaggcacc aaataccgcg gagactttga
    25861 agaacgtatt aaaaaggttc tcaatgaaat ccaaaaccag ccgaaagcaa ttgtttatat
    25921 agatgaaatt catacaatag tgggtgccgg ggccgtatcc gacggtgcga tggatgcgtc
    25981 aaacatcata aagccttttc ttacacaggg cacattgagg tttataggct cgacaactta
    26041 tgaagagtat aaaaagtact ttgaaaagga cagggctctg tcgaggagat ttcaaaaaat
    26101 tgatgttccg gaaccgtcaa ttgatgacac gttcaagata ctcaaaggtc ttaaggacag
    26161 atatgaagaa tatcacaagg taaaatacac agacagtgcc ttaagacttg ccgcggagct
    26221 ttctgcaaaa tacatccagg atcgtcatct tcctgacaaa gcaatagacg taattgacga
    26281 aaccggagct tatgtgcgtc ttcatgcaaa agatgaagac aaggtaatta ccataaaaaa
    26341 caaggacata gagcgcacgg tgtctgcaat tgccagaata ccgatacaga gtgtatccag
    26401 ggatgaaatt tcaaaactta aaaaccttga tgtaaaatta aaatccacaa tattcggcca
    26461 ggacaaggct attgacactg tggtgcaagc tataaaaagg tccagggcgg gattcaatga
    26521 aaatgaaaaa cccgttgcct cccttctttt tgtcggtccg acaggtgtcg gtaaaactga
    26581 gcttgcaaaa cagttgtccc ttcacctcgg tattcctttt ataaggtttg atatgagtga
    26641 gtatcaggaa aagcacactg tttcaaggtt gataggtgct ccacccggat acgttggata
    26701 tgaagaaggc ggacttttga cggatgcaat aagaaaaact ccgcattgtg tgctgcttct
    26761 cgacgaaatc gagaaagcgc accccgatat ttacaatgtg ctgcttcagg taatggatta
    26821 tgcggtactt acggacaaca acggaaaaaa agcggacttt agaaatgtaa tactgataat
    26881 gacctccaac gccggtgccc gggaagtcgg aagaacgctt ataggatttg acagcagaaa
    26941 cgttgacaga agcgccatga caaaagaagt tgaaagaata ttctctccgg agtttcgaaa
    27001 cagacttgat gatattgtgg tattcaacca tatcaatgaa gagatggcgc tgcttataac
    27061 caaaaaagcc ataaatcaat tcaaggaaaa actaaaaacg aaaaatatca agcttaaagt
    27121 gacggaaaga tgctgcaaat ggattgccca aaaaggtctt tcgtcaattt acggtgcccg
    27181 tgaaatattg aggtatgttc aggacaaaat aaaaacgtat tttgttgacg aagttctctt
    27241 tggagagctt tccaaaggcg gcactgcaat aatagacgtt gtggacggag aaattaaaat
    27301 aagcaaaaaa actcaaaggt gatagtcgat gcccgttttc agacttacag acaaattggt
    27361 ttttccccat ccgtcacttg ccgatgaaga tggaatttta gcggtgggag gagacctttc
    27421 gtgcgagcgt ctcctccttg catataaaaa cggaatattt ccctggtttt cggaagacga
    27481 gcctatatta tggtggtccc cgaatcccag gtgtgttctt ttcccaaaag acataaaaat
    27541 atcgaggtct atgagaaaat ttttaaagaa acagctctac gaagtcacct ttgacacatg
    27601 cttcagacat gtaattgcca tgtgtgcaaa gttgagagaa ggcaatacat ggataactcc
    27661 cgaaattatc gaaagttatt ccaaactgca cgacttagga ttcgcccatt ccgttgagac
    27721 ctggtatgaa ggtcgccttg tcggaggact ttatggtgtc tctttaggaa aatgtttctt
    27781 tggcgagtcc atgttttcga ctatggacaa cgcttcaaaa acagccctta tcactctatg
    27841 tcagaaactc gaggaaaaag gttttctttt gatagactgc caagtctatt caaaacacct
    27901 tgagtcttta ggagcggtaa atatagaccg tgacctgttt ttaaaatacc ttgaagccgg
    27961 gctttcccat gagacactga gaggaaattg gaagttcttc aatgagcaaa aacaagttcg
    28021 aaataattaa aatctttaaa ataactttaa aaggttggta ggatgtatga atgcaaaaat
    28081 caataaaaaa ctgtttttta tccttcttat tccccctggc gtacctaata cagtttctct
    28141 cctccagggc ttccggcctt gcggaaaaaa tttattcaag aggtgtttac agaataattg
    28201 caagattttt aaatctaatt tcaggccata tacccgtatc cattgcagaa atactggtag
    28261 tgctctctat tttgtttgca ttgttttaca ttgtaaagac aattatcagg atgataaaat
    28321 cctcatcaaa agcttttaaa attttatgca acgccctcgt caacatcctt accgccgtaa
    28381 gcctgctgta ctttggcttt atgctgctgt ggggaatcaa ctatcaaagg cttccttttt
    28441 cccaaattgc caattacgac acaagtcccg cctccacaga tgaattgctt gaggtatgta
    28501 aaagtcttat ggagcacgca aataggctta gaaaacatgt tgaggaagac aacaacgggg
    28561 ttatgaaact ttcagccagc gtaaatgaaa cattgaaaag agcctgttta ggttatgaag
    28621 ctgcttccaa aacatacccg gagcttcatc acaattatgg aaggccaaag ggggtaatac
    28681 tgtccgaagt aatgtcctat cttggcatcg gaggagttta tttccccttt acaggagaag
    28741 caaacgtaaa tatttcgatg ccccatactt caattccttt caccgcttgc cacgaaatgg
    28801 cccatcaaat aggttttgcc agagaagacg aggcaaactt tatagcctat attgcatgta
    28861 aaaatcatcc ctcaccggat tttcagtatt ccggaatttt atcagctctt ataaatgcca
    28921 ccaataccct ataccgctac aaccgggacg agtattttaa attgagaaac agttttagtg
    28981 aaggtgtaat ccgcgacctt gacgctttaa acatctactg ggaaaaatac gacactccca
    29041 tagaagattt ctcatcctcg gtaaacaaca cctaccttaa ggcaaacatg cagcaagacg
    29101 gagtaagaag ttacggaaga atggttgatc tccttatcgc agaatacaga agccggaaat
    29161 aagaagcatc gacggcccat attcaaacaa actctccggg agactcaaat atgtccacat
    29221 ccttatcttc cattttgcgg gttttatccc tgtaaaccgc gagataaaac gccagcagaa
    29281 tgaaacctgc caatcctgaa ggtatactta tcagcacagg ttcaagatag atccccactc
    29341 ttggcagcgt attcgcaaaa ttctttaatg tcaccgttat aaagaaattt gccattgata
    29401 taagaaaagt aatgcctaca gtctgccata aacacgacct tcccacctca accgcctttt
    29461 taaaagctga ggtaaccttc atactgtcga ccaacattgc cggataccag taagaaagaa
    29521 tacatttaat accatatatt actacataaa gcattactgc aaccacaaaa gttatggcaa
    29581 ttcccaaaaa caaaaccgaa gttccaatct ctttgagcaa ccaaagcaag aatataaaaa
    29641 gtgccaaaat aagcataaac gctaagctca aaacagtatc aacgaggaaa ttgaatatct
    29701 tgtaaataat aaactttggc agattcattg ccatttgagg aaaaaaatca cccaaatccg
    29761 cattaccggt ctccaatcct ttgtttacca taccataagt tgcaggtacc acaaacaaac
    29821 tcaacaaaaa agatacaata ccggcaatag tcgaagccgt aaaccacggt ttcatgattt
    29881 ccaaatacgt tcttagcatc tccatggaat ccatctgtgc atattcagct acggaactta
    29941 attcattaat gccttccaat atttctgcat tattcacggt tccggtaata atattcggga
    30001 tggcaacagc aataatcatg ggcaacgcaa gcaaaaaatg cttccccaaa aattcgaaca
    30061 cttcttgtaa atatttcatg ccgacctcca tttcataaag caacaaaaca ctcataccaa
    30121 attataaatc agtttccttt aattgtccat tcaaaatttt acttttttcc catatagacc
    30181 tctaccttgt gtgtgtcttt gtcattgaca agctgaactt ttccgtcatc gcaaactttt
    30241 ccgtcaacaa tgaccttttt gactccggta ttcactcctt cagggttttt cacttctata
    30301 atataatcag tatcataata acgatattta atcgtaaaat ccgtccattt tcccggtatg
    30361 caagggtcta tctcaagagt ttctccccgc tttttaaatc ctaaaatata ttcaaaacca
    30421 acacgataga tccatcccgc cgagcctgta taccaggtcc atcctcccct gcctgtatga
    30481 ggcggaactg aataaacatc cgcagccatt acataaggct caaccttgta cctggaatat
    30541 tcaatatggg ttcttgagtg atttatagga tttaacaggt caaaaagctc catcgctttt
    30601 tccccgtctc ccatctttgc aaaagccatg acaacccagg cagcggcatg ggtatattgt
    30661 ccaccgtttt cacggactcc cggcacataa ctctttatat agcccggttc caaatctcct
    30721 tcgtcaaaag gaggagtaag aagctttata agtccctcat cccgttttac cagatagttt
    30781 tcaagggcac tcatggcttc agcaatcctc tctttgtctc ctccttcgga tattacagcc
    30841 caagactggg ccagagagtc aatctggcat tcactgttct gtatggaacc caaaggcacc
    30901 ccgttgtcaa aatatgctct tctgtaccac tttccatccc aggcattttt ctcaatattc
    30961 tcaacaatcc ggtctgccgt gtccagatac ctttttgcaa gttcattatc acccattctt
    31021 tcgcacagcg gagcaaaatt tttaagtatg gaataaagga accagccaag ccatacactt
    31081 tctccctttc ctttgttgcc cactgtattc attccgtcat tccagtctcc ggagccaatt
    31141 aacggtattc catgttctcc aaactttaaa gaccggttga tggctctgat acagtggtca
    31201 taaagggtcg ataccgtatg agatatcctc ggaacacgat aagcttcatc ttcaaattcc
    31261 tttaacggtt catcctctaa aaacggtgtc tcttcgtaaa gtatgtcata atccccggta
    31321 attcttatat attcaatcgt agcatagggc atccatagaa ggtcatcgga aaattttgtt
    31381 ctcgtacctt tgtatttttc ttcatgccac cagtgctgta catccccttc tataaattgg
    31441 tgccttgagt gaagaagtat ctggtttctg gtggcctccg gccatatatg ggtcaatgag
    31501 atactgtcct gaagctgatc tctaaagcca tatgcgccac ccgactggta aaagcctgat
    31561 ctcgtccaga gcctgcagga aacaacctga tacagaagcc atccgttaag cagtatatcc
    31621 attgccgtat tcggagtttc aaactgcagt gccccaagct ttaattccca gaatttcttc
    31681 acttcgccca atgctttttt agcctcttcc aattttttgt atttcgcaga aagctgcctt
    31741 gcttcttctt cgtctctgcc tgctccaaga aggaaaatga tctctttttc ctcatcaggt
    31801 ttgaggttta cactcacgct tatggcagca caagggtcaa aacccgctcc ggttgttcct
    31861 gaaagagaag tacgttttat tccttcagga tttgcaatat ctcctgctcc aaagaactct
    31921 tttctgtcac aggtcagtga gttgactttc aatgaagaat caatgaaggc aactctgccg
    31981 ggaaactcgt cattatagtt attctttatc acaatcatgc cattgtcagc cttagtattt
    32041 atatgcatgg cagtaaactg atcgctgact ccaaggaccg gccttatata atatgtcaga
    32101 ctcaagcccc tattttcctg tgattgattt tttagtttca gaatactaat ttttaccgaa
    32161 tcatcaaccg gaacaaactg caccatttcc tgttcaatgc catggcttgc atgactgaag
    32221 accgtatagc caaaaccatg ccttatcata tacggctctt tttctctcac aggcaacggt
    32281 gttacggacc atacatctcc tgcatgttca tccatgacat acagtatttc tcccggtgta
    32341 tcgcttaccg ggtcgtttga ccacggtgta agcttgttct cccggctgtt ttcaaaccat
    32401 gtatagcctg aaccggactc cgttactata aatccaaatc tctgattgga aattacattt
    32461 atccatggca gaggagtatt ctggccgttt tcaaggaaaa tgacatactc tttgccatcc
    32521 ttgccaaacc cgccaagacc gttgtagaag ttgagctcca aatcctttgc aagcttggag
    32581 tcgtaacttg ccggtttctt ttcaaattgc ttaaactctg ccaaagcaat gcttcttgca
    32641 tattttacct ggtctttcaa gtcacccgca tcacctttta atattatcct tgaaaccgaa
    32701 caaatcaaat caatatcctc cggaggcatg ttacttttct taagaataaa cactcctccc
    32761 ggtttgttta tcaggtcatg ggcatgactt tcggcaatta tatccattag caaactgttt
    32821 accgggttgg tgtagctgtt ttcttcctca ttgaggatca ccagatccac ggccagtttc
    32881 tttaaacgcc agtattcatg agccttcagt acttccctca caatatctat gtcatcggtt
    32941 ttgtcaagca tgacaagtac aatcggtata tctcccgaaa taccataagg ccaaagaccc
    33001 ggttgtcctt ttttgttgtt cattacccat ttttgtttct gtctttgcag aggactgata
    33061 aacagtatat gggaaatcat atcctgatac agttctattt cttccgtatc aagatttaaa
    33121 tatcttgctt ccactcggct ctttgtaaca gccatgccaa gctcatcctt tatcacctgc
    33181 gggcttttaa acttcgtggc catctccact acatcttccc gactgtttgc caccgcagtt
    33241 acaaaggata tttttactga tttaccgggt tcaactctga ctatctgcct gaaactcata
    33301 accggatcca acactgcacc aacggaattg gtaagcggcc tgtgaggttc cagcgccacc
    33361 ggttccgaca catttctgcc tcttcctata aactgcattc tgtcggtttc atactgcagg
    33421 cttcctaccc cttctccttc caaaaccacg gtattcatta tccatacagg tttttccttt
    33481 tccgatcttg gccttcttcc ggcaatcaga cagttatgtt ccgccaaaaa ctccgtcctg
    33541 ataaacaggt ttccaaaggc cggatgggca atatccgcac cgtggtggga caaaaccggt
    33601 tcaaaatagc tggttatctc catcacacag ctttcctgtc cgtgatttgc caaagtaata
    33661 cttctaatct cagcattttc cccggcgcaa acaactatct ctgtcaatgt gtcaatatcc
    33721 ccgtcttttc tgtagtattt tgcttttccc gaagtaaact caactttgta ttcgtccggt
    33781 tttttccttc cgggtgcaaa ggtggaagtc catacttcat cgttctgtac atctcttata
    33841 tagaagaaca ttccataatt atccaaagtc acatcttctc tccagcgggt tacatccagg
    33901 tttttccatc tgctgtagcc ggtacccctg tcggtaacca tgactgagta gttgccgttt
    33961 gacagtatat gggccttcgg aagtacaggg tcaggcatac cgcactctct caggaaatct
    34021 ttctcatcat ataccacatc cttgaaagga agtattttct ccttgttttc ctttgtaaac
    34081 actatatttg acggtacttt ttccatcaga agaagttttg cggcatcaac cacagggtcg
    34141 gcatggaaac gtttttgcat tatattgtcg ttaaaatagt tgttcagagc caatatgctc
    34201 ataccctggt ggtgagccat atagctcttt acaattcctt tcttctcgcc taaaggaatt
    34261 ctttcgggag tgtaatcaat tgcctcgtac ataccataat gtccgtaggc accctcggca
    34321 atcagtcttt tcaaattgtc cattgcatct ctcggaacca aaggaagaac cagcatggtc
    34381 gcataaggag aaacaaccat atcctcaaca agccctcttt ttagccccag ccatggcaca
    34441 ccaaaagcct tgtattggta atccaggttt atgtcaaagg aataaaatcc cgactcggat
    34501 ataccccagg gcagatttct ctgttttccg tactttttct ggctccttac cacaaaggaa
    34561 taggtttcgt caagcaaagt atttttgtga ctcttcataa tgagtaaagg cataaaatat
    34621 tcaaacatgg ttccgctcca tgaaaccatt cctttgtacc gatctatctg ggtaagtgtt
    34681 ctgccaagct tgaaccagtg ctgctggtcc acctctcctc ttgcaatggc aatgtaactg
    34741 gtctgccggg cttcagaagc cagtaagtca taataggaat ttgtaagact gttttcttca
    34801 atattgtatc caatggaaaa cagctgcttc tttttgtcat acaaatgcac aaattccgtc
    34861 tcatcagcaa ttctgcatat cctgtttatt aaatccacat atcttttcac cagtttgtcc
    34921 gcactttccg ctgccccttc caaagcctcc ttaagcctgt caagtccttc tatattcttt
    34981 tgctgtccgt cttttaactt tttcctgagc ttttcgattt gttttattgt ttccctgtat
    35041 accacaggca tggctttgag ggagtagtcg gaattcagct tccttattat gccatgaaaa
    35101 gcttctttta tatcagcctc gctcttttca aaagcttcgg tcagttcgtc aatcatgtcg
    35161 caccaaggca tgtaggtgta cagctcaatt ttcagcatct ctatcatgct gtcaaccttt
    35221 gccttccata catccttgct gtccttcatc ttatttccgt cttccgaaag ctttgtcaat
    35281 gccttcatca tctgcggtat atccacataa cttctgcctt cggaaattac aatgcactct
    35341 ttgaggcatg aaatatcctt gtaagggttc tcgttttcgt cggcaatcag acttgccgta
    35401 tcccttattc cgtcaataaa cgccctgtcc tcaagaggtc tgttgagata ctccgccaaa
    35461 ccttctttga gagttatgag gtaacagaca aagtttccgc tgtcaacggt ggaaatatac
    35521 cttggtctta aagtctccag tgtccgtgta tcataccagt tgtaaagatg gccgttccac
    35581 ttttccatct tttcaacggt actcattgtt cttgaaataa tgtcacaaag ctccaaagtt
    35641 cctatataac ccaagtctct ggctgtgaga gctgcaagca tacccaatcc aatattggtt
    35701 ggggacgtcc tgtacgctat gccattcgga gggtcttcct gaaagttgtc cggcgcaagg
    35761 tagttgtttc tcctgtttac aaactcctca taatatctcc atgtctttct ggcaatacgt
    35821 ctaagttcca gattctcctc gtcgcttaaa gtctctgttt tgtaaaccgt ctctttgctt
    35881 atccaataag ctataaaagg cgatgaaacc cacacggcaa acggaagaac ggatactgcc
    35941 gccgaaaaac cggttttaaa tgcaaaagcc agaaccacaa caaccagtgc ctgaaatgct
    36001 gccgccttca tctttattac ataaccttta agtgaattct taaggcctct ttcagcatcc
    36061 agtgcggtta cccactcaag catgttcctt tttgtaaaca gaaccctgac aaggctcaat
    36121 accgccgcat gcaccataag ccatgcatta tacggcagga agacaaactg caatgtcatt
    36181 tgcagaaaag acgccttcag cccgcatatg gcaggtttgt atctttttga agtaattgcc
    36241 cctaaaggct ttgatgcaat atagtctata gttcccgtaa tcagcggaaa atatatagtt
    36301 aaaagggagg cccccaacca gaaaagggaa ctgcccggca aaatactgaa tcccaaagca
    36361 ataagcagcg ttattgaagg tgctactata cttcttcgaa ggttatctaa tatcttccat
    36421 ctggaaatca atgaaagagg attctttatc acatttccct ttctgtcttt tgttttgcca
    36481 cgaagccacg gcagaagctg ccagtctccc ctcacccaac ggtgaagcct catggcatag
    36541 gagttcagct ttgaaggata accatcgata aactcaatat ccgtcacaag ccctgctctg
    36601 acatacgaac cttcaagaag gtcatggcta agtacggtat tgtcgggtat ggcatccttc
    36661 aaaagttttt ggaaaacctc aaggtcatat atacctttac cggtaaatat cccctcgccg
    36721 aaaagatcct gatagacgtc tgaaatagcg ctggcataag ggtctattcc ttcctcaccg
    36781 gcaaatatcc ttgaaaacag cgacttgtta acgctttcaa tatcaaaacc tattcttggc
    36841 tgtaaaagcc cgtagccctc ggttactatt cccttctgtt cgtcaatcac aggcctgtgc
    36901 aaaggatggg ccatggttcc tatcagcttc ctggccgcac ccaaaggcag tatggtatct
    36961 gcatccaaag taatgacata ttttattttc ggaagctgtg acacgtcatg ggacattatt
    37021 gaatagctcg tagttcttga gcccagaagg acttcgttaa actcaagaag agctcctctt
    37081 tttctctccc atcccatcca tttgttctgc ttttcgttaa actgtctgtg tctatgaaaa
    37141 taataaaata tgtcccggga gtctttttct ccgccttcgt tttttctgcc atatttttca
    37201 ttaagctctg caattctgcc cagcgcagtt tcaattatct ttttatcacc ggccatttct
    37261 ttgttgggag catccttgaa atccccggca attgagaaat acaaattctt ctcccggttg
    37321 gcaagataat atacttcaag gttgtcaatc agctccctcg cccgattctc gtcaggaagc
    37381 agagcaggta tgacaaccat tgtggcatac tcttcaggta ttccgttttc aaagtcaagt
    37441 tttggcagca gcgaaggctt aatcatcttg cacaataccc agtttacaaa attaactgca
    37501 atgtcggttg caggaataat cgttgccaaa actgcaataa ttgacagggc aataccgtat
    37561 ttctccgctc tgaaaagaga atacttcgtc acgcatagca ataataagac agttataaac
    37621 ccgataaaac caaaatacaa acatgcagga tgctctttta ttctttcaaa catcctttga
    37681 ttaaagcttt tttcatagcc tatttctttt tccagctcac aaataccttt tccgacaaga
    37741 taatacccta catgggccaa acgcttatcg gtcaaattgc cgttttccac cgcatttctg
    37801 gcaagttcaa cagccttttt ggcaacatgg gattctgaaa ctttatattt tagagccagt
    37861 ttttccactc tgtttctgta ataatttctc gaatcaaaat ccatcaagga ataaaaacct
    37921 gagggatctt ctcttaaaat ctgctccact ttgctaagct gttcaaaaat atccacccaa
    37981 ttaacggttg aaataaattt caggctcatt atacagttgc caatggatgc cttgcttgct
    38041 gtctgttcat tatgctcttt ctgggtaatg tcatcaaccg ttgtgccgct ttcaccaagc
    38101 ctttcatcta tataacgcag aacatgggta taggctcttc ccatctttct gaatttgtat
    38161 gcaagatatt caataaatgc cgaatttacc tcgtatttcc ctttaagctc attatctatg
    38221 gcagttataa gttgagtggt gttttcaata ttttcatcaa aagctttaag tatttcttcc
    38281 acttttcttc tttgttcctg ggcttttgca attttttcgc aaatatatct tgttttttct
    38341 ataagcacaa gtttgagcat aatagggaaa gcccacaatt cccttccggt aagtacattg
    38401 ttggactgat atgcctttat gtagttaacc agcacttttt catcaatcct gccgtcggta
    38461 tgggaaagca attccagggc aatggaatat atccgtgcat agcctttaag gtgtccgctg
    38521 tcaagcacgg gaagttttgc atagacctcc tttgtaaggt cccttcttaa actctttact
    38581 tgttcctcta taatataaaa attatccaaa agccattctg cagcaggcgt agtgctgata
    38641 cccttttgta catcttcatt catttcttta tatacggaca ttatatacct gtaattatca
    38701 ttcatcctgg gtattggcca ggaaaacata ctctttttcc cggatacaga atgttcaatt
    38761 gctatttctt tcgcataggc ttccagttca tcaaaagtca aagatgcatc ctgcactttt
    38821 agttgacgtt gtctttcatt gcaatttgaa aaaattgcta acaaaaataa gcacaataat
    38881 ataccaaata aacccaacag atataaaatg tatagttgca tctgcatcta tcaactcctg
    38941 ttttcatatt ttgacgctta ttttcctgca aaccattaac ataaaagaat ttgtcatagg
    39001 agcatacttt attatatgcc aaatagagaa attcaaaaca taagtgattt aaaataatac
    39061 ttgataaatg aactgttatc cataagtata tcattaaata aatgttttaa caaatatact
    39121 tcgcgccaat ttgcatcaga ttatcgttta cctatatttt ttctcagaat ttcatacatc
    39181 agtatgcctg cagccaccga agcatttaac gactcagccc tccccggcat gggtatccta
    39241 accagaatat cggcaaaatt ttttacttct tcacttatac cgttagcttc gttcccgata
    39301 acaattgcaa tattattttt gtattcaaga tcaaaataat cgcaacttcc ttcaagatgg
    39361 gcagcacaaa tcttaattcc tctttttttc atcctgtcca ttgtctcaaa aatatcttga
    39421 ctttgacata tgggaatatg aaatatagaa cccatggtgg atcttaaaac cttgggattg
    39481 tagacatcca cacatccttt ggatactatg acgcctgtca ttcccgctgc atcagcggtt
    39541 ctaattattg tgcccatgtt tccggggtcc tgaactgaat ctaaaattac aaaaaaattt
    39601 ttttcatccc aaacatcttc aatgtcacag tttttcatac tcaacaccgc caatatcccc
    39661 tgggggtttt gagtatccga tatttccata aaaagtttat gaggcagttg aaaaaccgga
    39721 tatcctccgt tgctcacctt ctttaaaatc tcatagccgg aatttgtttc ggcaagtttg
    39781 tctgaaacaa gaattctttc tatttgaact ccttccttta gagcctcttc cacaaacctt
    39841 attccttcaa taaaaaacaa tttcttttct tcacggtatt ttttttgttt cagggactta
    39901 acttctttta taatcggatt ttgtgcactt gttatgtagt tcatttcatc acctcaaaaa
    39961 agtccaaatc ataaaaaaat gttcaaaaat tattatatca aaaaaaagag agcctattta
    40021 aagctctccc cttttaattt catatataat tctaatttat catcttcatc ttatattatc
    40081 atcgacttat ttatattacc gctttaactt tttccaccag ctgtgcaaaa gcttctgcat
    40141 catttacggc catttcagcc agcatctttc tgtttaaagc tataccggat tttttaagcc
    40201 cgttcataaa tttgctgtag cttaaaccat tcattcttgc agccgcattg attcttgtaa
    40261 tccaaagctt tctgaaatct ctttttcttg ctcttctgtc cctataagca taaaccagtg
    40321 atttcatcac tgcctggttt gcaattctaa aattcttgct tttagcacca aaataacctt
    40381 ttgccagttt caatattttt ttatgtcttg cacgggttct taccccacct ttaactctcg
    40441 acataataag aagcctcctt ttttacttgt atggaatcaa ctttttgatt actgatgcat
    40501 tagccgaaga cgcaattgtt gatttcctca agtttctttt tctctttgaa gtttttttcg
    40561 tcaatatgtg acttttatac gcttttgctc ttttaacctt acctgtacct gtcaatttga
    40621 atctcttctt tgaagagctg tgagtcttta tcttaggcat aagatttcct ccttaatttc
    40681 tataattact gtttaggatt aagaatcata aacatgtttc taccttccag ttttggcttt
    40741 ttctcaacaa cagcaacatc tttaaccgct tccgcaaatt tctcgagcac ttgttggcct
    40801 aaagaggtgt agttcatttc tctgcctctg aacttgacac tgaccttaac tttgtccccg
    40861 tccttcaaga acctgagtgc atttttcaat ttaaagttaa aatcatgttc ttcaatcgaa
    40921 gcagacagtc taacctcttt cacattaatt accttttgat tctttcgagc ttctttttcc
    40981 ttcttggcaa gttcaaacat atacttgccg taatccatta tcctgcacac aggcggtacg
    41041 gcttgagggg caatcttgac caaatccaaa ttcttcgcat ttgcaatctt ctgcgcctct
    41101 ttcgaagaca taatacccag catcgtacca tcggtatcga tcaatcttac ttccttgtct
    41161 cttatttgct cgttgatcat taactcgttt ttgttaatag aaaacacctc cggcttttcg
    41221 aaattcgcgt tattttttat ttaatgcaaa aaaagtgaat cattaaaatg atccacttat
    41281 ccctcacaaa actaatacac ttactgccat ttacatacag caacgttgcg gtattaaccc
    41341 tacaaaacag aatttgtaag gtgagaagtg gataacttct tctttatttt cgctttttta
    41401 tagtatcaga tgataaatta tttgtcaata gttttataat attttttatt atcagtatac
    41461 tttgggattt tcatttacat atttcaagcg gttataccgg atatcgttaa actccttcgg
    41521 ctcgcccaca caaaccagtt tccacccttc catttcatcg aggttgggaa aatatctgtc
    41581 tgcagaatac gcaccgttaa atttggtaac atgagcctcg gagcaatatg gcaacagctg
    41641 tgtgtatacc tcttctccgc ctattacaaa aatatcatcg gagttatatt ttttaagctc
    41701 caaaaaaagc ccgtcaacgg aacgacatat tattattccg tctttttcaa tgttttcact
    41761 cttacttaat attatattta ccctatcctt taaaggttct tttccgggca acgattcaaa
    41821 cgtcttcctt cccattacca caactttatt caaagtcatc tgcctgaaaa atctcatatc
    41881 ctcgggaata cgttgaagca gattcccttt atatccaatt ccccagttag aatcaaccgc
    41941 aacaatagct ttcattttgt cctccttctt agatggcaac agggatgttt tttatctggg
    42001 gcccggcctg atagtcctcc agcacaaaat cttcaacttt aaaatcataa aaatcttttt
    42061 tctcgggatt aatccatagc ttcggtgctg gataaggagt cctttgtata agttctttta
    42121 ccaacggtat atgcctgtca tatatatggg catcggcaat aacatgcaca agttctccaa
    42181 cttccaaatc gcagacttgt gcaaacatat gtactaaaat tgcatattgg gccacattcc
    42241 agttgttcgc caccaaaaca tcctgggaac gctgattaag tattgcgttc aattttcttc
    42301 cggtgacatt gaaagttatg ctgtatgcgc aaggatacag gttcatttca tgaaggtcac
    42361 tatgattgta catgttggca ataatccttc tgctgtaagg attgtgcttt aagtcataga
    42421 taatcctgtc aacctggtca aactctcctt cgggatattt atgcttaata cttaattgat
    42481 aaccgtacgc cttgcctatc gaaccgtttt catcggccca gctgtcccaa atatgactgt
    42541 tgaggtcttt tatattattg gatttctttt gccatatcca aagcagctca tcaattgcag
    42601 ctttcagatt tgtcggcctt aaggtaagga ttggaaactc ctccgacaaa tcatatctgt
    42661 tcacaacgcc aaatttcttg attgtatggg caggagttcc gtcagcccat cttgctctta
    42721 ctttttctcc ttcggaagac actccgtttt caagaatgtc tttgcacatg gctataaaaa
    42781 tctcatcagc tttactcata agcaaactaa ccccacttat cactaatcat ttgttaatca
    42841 ttccatttaa cattatccct attaaacttt ttctttatat aagcaaaact ctcattttca
    42901 gatatcgaca tatcgacgtg atatcttcat aaatttcaca aaaatcattt gtaattttga
    42961 aaatgtaaat atattttaac ataacacaca aaaaaataat ataataaata gctaaaaaag
    43021 aatttacata attgtatatt ggcaccacca aagattctgg attacagata acagatctta
    43081 atgtataagc aaagaatttt ctgtttgcaa aatataaata attaaataaa acataaataa
    43141 agtacaaata aaaaatataa aaataaaaag aaggcaaacc aaagctcttg attttaatcg
    43201 ctcttttcag tttgcctttt tcctttttga ttaaagttca gtcaattatt ctccacttt
//