DNA/GUI (DNA Graphical User Interface) is an interactive software
system for rapid and efficient analysis of images of the types used in
genome mapping, such as autoradiograms and electrophoretic
gels [1]. Images are digitized using a commercially
available
charge-coupled-device (CCD) camera system and analyzed on a
graphics workstation using a menu-driven user interface. DNA/GUI
features automatic lane and band detection,
simultaneous display of multiple images and a unique spatial-normalization
algorithm. Images and their associated data are archived and easily
available for later recall. Preliminary results indicate that DNA/GUI is a
useful tool in the analysis and comparison of images used in a variety of
applications such as genetic-linkage analysis and DNA restriction
mapping. The interactive display software is based on the X Window System
and is therefore readily portable to a variety of graphics workstations.
[1] HA Drury, KW Clark, RE Hermes, JM Feser, LJ Thomas Jr., and H Donis-Keller. "A Graphical User Interface for Quantitative Imaging and Analysis of Electrophoretic Gels and Autoradiograms." BioTechniques, vol. 12, No. 6 (1992), pp. 892-901
Version 2
Version 2 should be ready the autumn of 1995. its release has been plagued by personnel shifts. It will run on SPARC, DECalpha, and SGI platforms. If you would like to be notified of its release, please us with the following information: