Dialyzer package:nlme R Documentation _H_i_g_h-_F_l_u_x _H_e_m_o_d_i_a_l_y_z_e_r _D_e_s_c_r_i_p_t_i_o_n: The 'Dialyzer' data frame has 140 rows and 5 columns. _F_o_r_m_a_t: This data frame contains the following columns: _S_u_b_j_e_c_t an ordered factor with levels '10' < '8' < '2' < '6' < '3' < '5' < '9' < '7' < '1' < '4' < '17' < '20' < '11' < '12' < '16' < '13' < '14' < '18' < '15' < '19' giving the unique identifier for each subject _Q_B a factor with levels '200' and '300' giving the bovine blood flow rate (dL/min). _p_r_e_s_s_u_r_e a numeric vector giving the transmembrane pressure (dmHg). _r_a_t_e the hemodialyzer ultrafiltration rate (mL/hr). _i_n_d_e_x index of observation within subject-1 through 7. _D_e_t_a_i_l_s: Vonesh and Carter (1992) describe data measured on high-flux hemodialyzers to assess their _in vivo_ ultrafiltration characteristics. The ultrafiltration rates (in mL/hr) of 20 high-flux dialyzers were measured at seven different transmembrane pressures (in dmHg). The _in vitro_ evaluation of the dialyzers used bovine blood at flow rates of either 200~dl/min or 300~dl/min. The data, are also analyzed in Littell, Milliken, Stroup, and Wolfinger (1996). _S_o_u_r_c_e: Pinheiro, J. C. and Bates, D. M. (2000), _Mixed-Effects Models in S and S-PLUS_, Springer, New York. (Appendix A.6) Vonesh, E. F. and Carter, R. L. (1992), Mixed-effects nonlinear regression for unbalanced repeated measures, _Biometrics_, *48*, 1-18. Littell, R. C., Milliken, G. A., Stroup, W. W. and Wolfinger, R. D. (1996), _SAS System for Mixed Models_, SAS Institute, Cary, NC.