PBG                   package:nlme                   R Documentation

_E_f_f_e_c_t _o_f _P_h_e_n_y_l_b_i_g_u_a_n_i_d_e _o_n _B_l_o_o_d _P_r_e_s_s_u_r_e

_D_e_s_c_r_i_p_t_i_o_n:

     The 'PBG' data frame has 60 rows and 5 columns.

_F_o_r_m_a_t:

     This data frame contains the following columns:

     _d_e_l_t_a_B_P a numeric vector

     _d_o_s_e a numeric vector

     _R_u_n an ordered factor with levels 'T5' < 'T4' < 'T3' < 'T2' < 'T1'
          < 'P5' < 'P3' < 'P2' < 'P4' < 'P1'

     _T_r_e_a_t_m_e_n_t a factor with levels 'MDL 72222'  'Placebo' 

     _R_a_b_b_i_t an ordered factor with levels '5' < '3' < '2' < '4' < '1'


_D_e_t_a_i_l_s:

     Data on an experiment to examine the effect of a antagonist MDL
     72222 on the change in blood pressure experienced with increasing
     dosage of phenylbiguanide are described in Ludbrook (1994) and
     analyzed in Venables and Ripley (1999, section 8.8).  Each of five
     rabbits was exposed to increasing doses of phenylbiguanide after
     having either a placebo or the HD5-antagonist MDL 72222
     administered.

_S_o_u_r_c_e:

     Pinheiro, J. C. and Bates, D. M. (2000), _Mixed-Effects Models in
     S and S-PLUS_, Springer, New York.  (Appendix A.21)

     Venables, W. N. and Ripley, B. D. (1999) _Modern Applied
     Statistics with S-PLUS (3rd ed)_, Springer, New York.

     Ludbrook, J. (1994), Repeated measurements and multiple
     comparisons in cardiovascular research, _Cardiovascular Research_,
     *28*, 303-311.