LOCUS NZ_ACVX01000007 117529 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00033, whole genome shotgun sequence. ACCESSION NZ_ACVX01000007 NZ_ACVX00000000 VERSION NZ_ACVX01000007.1 GI:256003900 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 117529) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 117529) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000007. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..117529 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene <1..800 /locus_tag="ClothDRAFT_3000" CDS <1..800 /locus_tag="ClothDRAFT_3000" /inference="protein motif:PFAM:PF07833" /note="PFAM: copper amine oxidase domain protein; KEGG: hypothetical protein" /codon_start=3 /transl_table=11 /product="copper amine oxidase domain protein" /protein_id="ZP_05428887.1" /db_xref="GI:256003901" /db_xref="InterPro:IPR012854" /translation="GIIAVLSVFIFTLIIGFTNQTALASNSVHRELKIYVDDKELQFT DAKPYISEFGRTMIPIRAVTESFGANVDWNGILKKVTITYDDIEIYFLVVHPDNIVVI NDLKTNQSKSVPMDSKPVIKNDRTFVPLRVIGEAFGYKVHWDASEYKVIIDTKNKQPV FFINPALSDTYYQCVANLNTDFENLIPQLKRASGRVKLTDEEREDYLSTAKSHVENVI GNVDYSKEFAPYYPDAPFTGIMKSVYDDAVKKFNNKGSEVYCGSFWR" sig_peptide 3..77 /locus_tag="ClothDRAFT_3000" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.963 at residue 25" misc_feature 162..458 /locus_tag="ClothDRAFT_3000" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" gene 769..1050 /locus_tag="ClothDRAFT_3001" CDS 769..1050 /locus_tag="ClothDRAFT_3001" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428888.1" /db_xref="GI:256003902" /translation="MKFIADPSGVDVLEEVEVFALGPTEVIVVGRLEFIYHEASDEYL EKFEGKLKKGVWYGTNIAVIFTLYRPAGSMEVDKIILDNTFEEIPSNKE" gene 1169..1834 /locus_tag="ClothDRAFT_3002" CDS 1169..1834 /locus_tag="ClothDRAFT_3002" /inference="protein motif:PFAM:PF08241" /note="PFAM: Methyltransferase type 11; Tellurite resistance methyltransferase, TehB, core; Methyltransferase type 12; KEGG: sat:SYN_00826 SAM-dependent methyltransferase" /codon_start=1 /transl_table=11 /product="Methyltransferase type 11" /protein_id="ZP_05428889.1" /db_xref="GI:256003903" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR013217" /db_xref="InterPro:IPR015985" /translation="MMSIKWEQEWDRIYKEQGEVQSEILPTVKVEKDIFKRFGCKKVM DLGCGTGRHTIYLAQNGYQVFAVDISETGIEVTRAKAEKLNLTNIEFAQLDMRNLSVD DNLMDAIMCVWTSGHGTFEDARKNLKEMYRILRLGEILVIDYVSREDENYGKGTEIEK NTFINNVEGEENIPHHYFAKEEIEELYTDFSDVDINPVDYYFTDSYGTRHTIKAFVVI AVK" misc_feature 1292..1603 /locus_tag="ClothDRAFT_3002" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature order(1304..1324,1370..1375,1448..1456,1505..1507) /locus_tag="ClothDRAFT_3002" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" gene 2112..3155 /locus_tag="ClothDRAFT_3003" CDS 2112..3155 /locus_tag="ClothDRAFT_3003" /inference="protein motif:PFAM:PF07833" /note="PFAM: copper amine oxidase domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="copper amine oxidase domain protein" /protein_id="ZP_05428890.1" /db_xref="GI:256003904" /db_xref="InterPro:IPR012854" /translation="MQKNFLFRRTGVIVTLFALILGFACNISFASTPMQRELKVYVDD REVKFPDAKPYISEAGRTMVPIRAVAESFGAKVDWDAVLRKVTITYDDIEIEFLPDYV EDVMLVRSIEKNQRKTVQLDSKPVIRNDRTYLPYRAISEAFGYKVYWDEKEYKVIVDT KDRQPVFYINPGLSDNDYECIANYNTDFDNLAQVLKRTDVEIQLTDEMRESYLYRAKN YIENIIGNVDYSKEFEPEFPTAPFTPVMEEVYNDAVKNSIIREVKFIADPSDIEVLMI HPIENRPYKVMVLGRLEFIYHEASDEYLEKFGGKLKKGVRYSTKIAVTFELKPNDAGL GHAILDNTFEEIE" sig_peptide 2112..2204 /locus_tag="ClothDRAFT_3003" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 31" misc_feature 2283..2585 /locus_tag="ClothDRAFT_3003" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" gene complement(3277..3477) /locus_tag="ClothDRAFT_3010" CDS complement(3277..3477) /locus_tag="ClothDRAFT_3010" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428891.1" /db_xref="GI:256003905" /translation="MESIQRNKQLINKFNEIQEEILKIGWNGIIQKYHPDINCDDENS EKTFKMYKCIYENMRKRLIVNP" gene complement(3722..3850) /locus_tag="ClothDRAFT_3011" CDS complement(3722..3850) /locus_tag="ClothDRAFT_3011" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428892.1" /db_xref="GI:256003906" /translation="MPWQTWVYLLAVVAILGVSFFLLLRSADKKLEGIKAKSKKKK" sig_peptide complement(3770..3850) /locus_tag="ClothDRAFT_3011" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.794) with cleavage site probability 0.484 at residue 27" gene 4052..5119 /locus_tag="ClothDRAFT_3012" CDS 4052..5119 /locus_tag="ClothDRAFT_3012" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: dps:DP2255 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428893.1" /db_xref="GI:256003907" /translation="MKTTLILGAGFSKNSGLPIQSEIPALLTKYKENSNFERSVSLVL ESFMRDVFGFEKDIYPQLDDLLTCIDISTNSEHHLGINYSPVHLKALKRLIIYRIFTI LEDSFTYSKEVEKLIRFFIENRLEYTGFLVLNWDTVLEKYISAIAPKAIIDYCNGGRY LTEDLRFEEKRDGKRKVEILKVHGSCNWLYCDNCRILINDTVSRVPNIRKVGFKKSDF KLFDEMKKVTDKVFFEDVRCFICGDIVSAHIATQSYRKSFRTNSFPSIWDKAEDMLTN SEKWVFIGYSLPQADYEFKHLLKICEHKLGHKKDRRLSIDVVLFDSETTAMRYKSFFG NKINRIFNSGIGEYISYLEST" gene 5192..5815 /locus_tag="ClothDRAFT_3013" CDS 5192..5815 /locus_tag="ClothDRAFT_3013" /inference="protein motif:PFAM:PF01926" /note="PFAM: GTP-binding protein HSR1-related; KEGG: gme:Gmet_0465 GTPase EngB" /codon_start=1 /transl_table=11 /product="GTP-binding protein HSR1-related protein" /protein_id="ZP_05428894.1" /db_xref="GI:256003908" /db_xref="InterPro:IPR002917" /translation="MKLKLNLNLNNARFEITAVRPEQYPKNDLPEITFVGRSNVGKSS LINTMLNRKNLAKVAATPGRTRVINFYNIDDKLYFVDLPGYGFAKVPKTMKTGWKDII ETYLIERKQLKKVIMLVDIRHSPTSDDVLMHEWLKAMRKSYVVVATKLDKIPRTKIKE RISDIRSILKLEDDVKIIPFSSETRQGRDELWDEILDESYFVESYFS" misc_feature 5282..5782 /locus_tag="ClothDRAFT_3013" /note="The YihA (EngB) subfamily. This subfamily of GTPases is typified by the E. coli YihA, an essential protein involved in cell division control. YihA and its orthologs are small proteins that typically contain less than 200 amino acid residues and...; Region: YihA_EngB; cd01876" /db_xref="CDD:133278" misc_feature 5297..5320 /locus_tag="ClothDRAFT_3013" /note="G1 box; other site" /db_xref="CDD:133278" misc_feature order(5303..5323,5363..5371,5378..5386,5432..5434, 5636..5638,5642..5644,5732..5737) /locus_tag="ClothDRAFT_3013" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133278" misc_feature 5375..5395 /locus_tag="ClothDRAFT_3013" /note="Switch I region; other site" /db_xref="CDD:133278" misc_feature 5384..5386 /locus_tag="ClothDRAFT_3013" /note="G2 box; other site" /db_xref="CDD:133278" misc_feature 5432..5443 /locus_tag="ClothDRAFT_3013" /note="G3 box; other site" /db_xref="CDD:133278" misc_feature order(5441..5452,5471..5515,5522..5527) /locus_tag="ClothDRAFT_3013" /note="Switch II region; other site" /db_xref="CDD:133278" misc_feature 5633..5644 /locus_tag="ClothDRAFT_3013" /note="G4 box; other site" /db_xref="CDD:133278" misc_feature 5732..5740 /locus_tag="ClothDRAFT_3013" /note="G5 box; other site" /db_xref="CDD:133278" gene 6080..6280 /locus_tag="ClothDRAFT_3014" CDS 6080..6280 /locus_tag="ClothDRAFT_3014" /inference="protein motif:TFAM:TIGR01683" /note="TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sfu:Sfum_1823 thiamine biosynthesis protein ThiS" /codon_start=1 /transl_table=11 /product="thiamine biosynthesis protein ThiS" /protein_id="ZP_05428895.1" /db_xref="GI:256003909" /db_xref="InterPro:IPR003749" /db_xref="InterPro:IPR010035" /translation="MFITLNGKQTEVDNGTTLVGLIQSKGLEPESIVVEYNYEVLPRE KWDSVVLKENDNLEVLRFVGGG" misc_feature 6086..6277 /locus_tag="ClothDRAFT_3014" /note="ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565" /db_xref="CDD:176353" misc_feature order(6197..6199,6251..6259) /locus_tag="ClothDRAFT_3014" /note="thiS-thiF/thiG interaction site; other site" /db_xref="CDD:176353" gene 6283..7050 /locus_tag="ClothDRAFT_3015" CDS 6283..7050 /locus_tag="ClothDRAFT_3015" /inference="protein motif:PFAM:PF05690" /note="PFAM: thiazole biosynthesis family protein; KEGG: dvm:DvMF_0800 thiazole synthase" /codon_start=1 /transl_table=11 /product="thiazole biosynthesis family protein" /protein_id="ZP_05428896.1" /db_xref="GI:256003910" /db_xref="InterPro:IPR008867" /translation="MDDKLIIGGREIISRLFIGTGKFPANRIIPDVVRMSGAQVVTVA LRRIDFDSDEENMLRYIPKDCILMPNTSGARNAEEAVRIARLARASGCGNFIKIEVIS DNRYLLPDNLETIKATEILVKEGFIVLPYMNPDLMDARRLKDAGAAAVMPLGAPIGTN KGLKTREMIKILIDEIDIPVIVDAGIGKPSDACEAMELGADAVLVNTAIATAGDPVVM AEAFANAVIAGRKAYLSGLGPVKEYAEASSPLTGFLR" misc_feature 6295..7032 /locus_tag="ClothDRAFT_3015" /note="Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728" /db_xref="CDD:73390" misc_feature order(6412..6414,6448..6450,6457..6459) /locus_tag="ClothDRAFT_3015" /note="ThiS interaction site; other site" /db_xref="CDD:73390" misc_feature order(6571..6573,6577..6579,6829..6831) /locus_tag="ClothDRAFT_3015" /note="putative active site; other site" /db_xref="CDD:73390" misc_feature order(6586..6588,6595..6597,6604..6612,6679..6681, 6685..6693,6700..6705,6757..6765,6772..6774,6790..6792, 6802..6804,6844..6852,6862..6864,6871..6876,6901..6903, 6916..6924,6931..6936,6943..6945,6964..6966,6973..6978, 6982..6996,7000..7005,7009..7011,7015..7023,7027..7029) /locus_tag="ClothDRAFT_3015" /note="tetramer interface; other site" /db_xref="CDD:73390" gene 7179..8288 /locus_tag="ClothDRAFT_3016" CDS 7179..8288 /locus_tag="ClothDRAFT_3016" /inference="protein motif:TFAM:TIGR02351" /note="TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: sat:SYN_00439 thiamine biosynthesis protein ThiH" /codon_start=1 /transl_table=11 /product="thiazole biosynthesis protein ThiH" /protein_id="ZP_05428897.1" /db_xref="GI:256003911" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR010722" /db_xref="InterPro:IPR012726" /translation="MSFYERYLEYKNFDFENFFDQVTDRDIINIINKDRRLSELEFLM LLSKKAVKYLEPLAQKANRITVQNFGKVIFLYTPMYLANYCVNQCIYCGFNITNNIKR RKLTLDEVEKEAYAISSTGLRHILILTGESRKESPVQYIKDCVKILQKYFRSISIEVY PLEENEYAELIEAGVDGLTIYQEVYDEEKYKALHLKGPKRNYLYRLDAPERACKASMR NVNIGALLGLHDWRTEAFYTGLHADYLQNKYPDVEIGLSLPRIRPHPCGSFVPDCKVE DRDLVQIMIAYRLFMPRAGIAISTRERESLRNNLIGLGVTKMSAASSTEVGGHTLGDK SDGQFDVNDRRGVEEMRQMIYSKGYQPVFKDWQAI" misc_feature 7179..8276 /locus_tag="ClothDRAFT_3016" /note="thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240" /db_xref="CDD:181720" misc_feature 7413..>7871 /locus_tag="ClothDRAFT_3016" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(7431..7433,7437..7439,7443..7445,7449..7457, 7560..7562,7566..7571,7656..7658,7719..7721,7851..7853) /locus_tag="ClothDRAFT_3016" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" misc_feature 7959..8261 /locus_tag="ClothDRAFT_3016" /note="Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149" /db_xref="CDD:157061" gene 8365..9009 /locus_tag="ClothDRAFT_3017" CDS 8365..9009 /locus_tag="ClothDRAFT_3017" /inference="protein motif:TFAM:TIGR02354" /note="TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: sat:SYN_00438 thiamine biosynthesis protein ThiF" /codon_start=1 /transl_table=11 /product="thiamine biosynthesis protein ThiF" /protein_id="ZP_05428898.1" /db_xref="GI:256003912" /db_xref="InterPro:IPR000594" /db_xref="InterPro:IPR012729" /translation="MNEFEIGLMSYLGREKLEKLGKVKVGIAGAGGLGSNCALHLVRS GFKNLKIVDFDVVEPSNLNRQFFFLDQLGRPKVLALKENLARINPDVMIEAIQQKVDR NNAKQLFDDCDAVVEAFDKVECKTMMAEAFASSGKFFVCASGLAGWGNSDEIRIRKVH DRFYIVGDFVTGVKEGIPPISPRVNIAAAKQADLILSFFLDDADNTVNVNCQEG" misc_feature 8365..8979 /locus_tag="ClothDRAFT_3017" /note="thiamine biosynthesis protein ThiF; Provisional; Region: PRK08644" /db_xref="CDD:181519" misc_feature 8467..8952 /locus_tag="ClothDRAFT_3017" /note="E1_ThiF_like. Member of superfamily of activating enzymes (E1) of the ubiquitin-like proteins. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like substrate...; Region: E1_ThiF_like; cd01487" /db_xref="CDD:30116" misc_feature order(8521..8523,8527..8529,8554..8556,8590..8592, 8716..8718,8734..8736) /locus_tag="ClothDRAFT_3017" /note="putative ATP binding site; other site" /db_xref="CDD:30116" misc_feature order(8737..8739,8791..8796,8812..8814) /locus_tag="ClothDRAFT_3017" /note="putative substrate interface; other site" /db_xref="CDD:30116" gene 9006..9248 /locus_tag="ClothDRAFT_3018" CDS 9006..9248 /locus_tag="ClothDRAFT_3018" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: tdn:Suden_2055 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428899.1" /db_xref="GI:256003913" /translation="MMGLDNLYRVLDANVNRTSEGLRVLEDLARFCYNDRLLSKRIKE LRHSVRKNIAGLVPNLISSRDSVNDVGLKNVNGDGY" misc_feature 9006..>9218 /locus_tag="ClothDRAFT_3018" /note="thiamine-phosphate pyrophosphorylase; Provisional; Region: PRK02615" /db_xref="CDD:179450" gene 9238..10080 /locus_tag="ClothDRAFT_3019" CDS 9238..10080 /locus_tag="ClothDRAFT_3019" /EC_number="2.5.1.3" /inference="protein motif:TFAM:TIGR00693" /note="KEGG: dde:Dde_1558 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase" /codon_start=1 /transl_table=11 /product="thiamine-phosphate pyrophosphorylase" /protein_id="ZP_05428900.1" /db_xref="GI:256003914" /db_xref="InterPro:IPR003733" /translation="MDIDRKASLLDLARANFKRVQEALRTVEESLKVLNENDLSKFYE SCRFETYSIEKEYFKVLTFENKKGRLNEIITGLYCITSEEHSKGRSNIEVVEKMIKAG VKIIQYREKKKSLLEKYNECKKIREMTLDSGVTFIVNDNIDIAMMVKADGVHIGQDDL PIEKVRELVGDEMIIGISTHSPTQAEDAVRRGADYIGVGPLYRTYTKEDVCEPVGLEY LDYVVKNINIPYVAIGGIKEHNMDEVLARGARCIAMVTEIVGADDIEEKISKVKSKFS RGVL" misc_feature 9466..10056 /locus_tag="ClothDRAFT_3019" /note="Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta...; Region: TMP_TenI; cd00564" /db_xref="CDD:73367" misc_feature order(9469..9471,9475..9477,9556..9558,9562..9564, 9697..9699,9769..9771,9820..9822,9826..9828,9847..9849, 9853..9855,9928..9930,9940..9942,9994..10005) /locus_tag="ClothDRAFT_3019" /note="thiamine phosphate binding site; other site" /db_xref="CDD:73367" misc_feature order(9556..9558,9562..9564,9568..9570,9652..9657, 9712..9714,9769..9771,9847..9849,9853..9858,9940..9942, 10000..10005) /locus_tag="ClothDRAFT_3019" /note="active site" /db_xref="CDD:73367" misc_feature order(9562..9564,9568..9570,9652..9657,9703..9705, 9712..9714,9769..9771,9856..9858) /locus_tag="ClothDRAFT_3019" /note="pyrophosphate binding site; other site" /db_xref="CDD:73367" gene 10082..11380 /locus_tag="ClothDRAFT_3020" CDS 10082..11380 /locus_tag="ClothDRAFT_3020" /inference="protein motif:TFAM:TIGR00190" /note="TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; KEGG: cla:Cla_1025 thiamine biosynthesis protein ThiC" /codon_start=1 /transl_table=11 /product="thiamine biosynthesis protein ThiC" /protein_id="ZP_05428901.1" /db_xref="GI:256003915" /db_xref="InterPro:IPR002817" /translation="MYTTQMDAAKKGIITDEMRIVAEKEGVHVEKLRELVASGKVVIP ANKNHKKLEPQGIGEGLRTKINVNIGISKDCCNFEMELEKAKKAIELKAEAIMDLSSY GKTREFRRKLVEMSPVMIGTVPVYDAVGFYEKDLKDISAEEFFEVVEKHAEDGVDFMT IHAGINRETAKRFKENGRLTNIVSRGGSLIFAWMELTGNENPFYEQYDRLLQIFEKYD VTISLGDALRPGSINDSTDASQIQELIVLGELTKRAWEKNVQVMIEGPGHMAINEIAP NMVLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAAANGADFLCYVTPAEHLR LPDIDDMKEGIIAARIAAHAADIAKGIKGAREWDYQMSEARRNLDWNRMFELAIDREK AERYRKSSMPEDEDTCTMCGRMCAVKNTNKALKGEKINIL" misc_feature 10088..11374 /locus_tag="ClothDRAFT_3020" /note="ThiC family; Region: ThiC; cl08031" /db_xref="CDD:186739" gene 11860..12384 /locus_tag="ClothDRAFT_3021" CDS 11860..12384 /locus_tag="ClothDRAFT_3021" /inference="protein motif:PFAM:PF00583" /note="PFAM: GCN5-related N-acetyltransferase; KEGG: vpa:VP1827 putative spermine/spermidine acetyltransferase BltD" /codon_start=1 /transl_table=11 /product="GCN5-related N-acetyltransferase" /protein_id="ZP_05428902.1" /db_xref="GI:256003916" /db_xref="InterPro:IPR000182" /translation="MYPLNIDGEELYLRDLKINDLPNLLKWYNNIDDFSLATGVYKPI TLKEILERYFKCQSSSKDFFAGIYIRKSGEMIGVLKGWLDCEKDLSAWINSIIIDPGF QRKGYGSKTVNLFIRHVKECCNVKRVYLSVAEENFKGMSFWKQQSFREVKKISKDRDS VSKCKSIVIMCREI" misc_feature 11863..12375 /locus_tag="ClothDRAFT_3021" /note="Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670" /db_xref="CDD:31856" misc_feature 12064..12306 /locus_tag="ClothDRAFT_3021" /note="N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00443" /db_xref="CDD:185998" gene 12409..12666 /locus_tag="ClothDRAFT_3022" CDS 12409..12666 /locus_tag="ClothDRAFT_3022" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428903.1" /db_xref="GI:256003917" /translation="MFFADGLKYQRKLSINITKDTFCFDRANNPVDKFATRQFDKWKL EIYNICGCIKFTMCFLYEVYVERCLKSFGFAKGIGKKRNGG" gene 12670..13782 /locus_tag="ClothDRAFT_3023" CDS 12670..13782 /locus_tag="ClothDRAFT_3023" /inference="protein motif:PFAM:PF00877" /note="PFAM: NLP/P60 protein; SH3 type 3 domain protein; protein of unknown function DUF1058; SMART: SH3 domain protein; KEGG: sun:SUN_0826 hypothetical protein" /codon_start=1 /transl_table=11 /product="NLP/P60 protein" /protein_id="ZP_05428904.1" /db_xref="GI:256003918" /db_xref="InterPro:IPR000064" /db_xref="InterPro:IPR003646" /db_xref="InterPro:IPR010466" /db_xref="InterPro:IPR013247" /translation="MLKFNKVFMYITASALSVSLWTCTSFAQQNKTGVTTASMLNMRE NPSTSTKIIDQIPNGTKVDIIETSNGWYKISYNGKTGWVYGSYVKVTETPKLTVTDET ILATLNKGSTGNSSTNSSTNNSAVNNSSSQVVDETIQKPAQNAASGENTENTVVKTGI VKASALNVRQGPGTSYSIINQLSNGAKVNIIKEESGWYQIKLANGSTGWVSGTYVNVN TTIASRGGLSENSAPAASNNSDVSDVRQQVVEYAKKFLGVKYVYGGNSPSQGFDCSGF VKYVFSNFGINLERVAASQAKQGTWVSKDQLLPGDLVFFDTDGGHNYINHSGIYIGDG KFIHASSGSGKKSVVISDLTSGFYANTYMTARRVLN" sig_peptide 12670..12753 /locus_tag="ClothDRAFT_3023" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.990 at residue 28" misc_feature 12787..12936 /locus_tag="ClothDRAFT_3023" /note="Bacterial SH3 domain; Region: SH3_3; cl02551" /db_xref="CDD:141512" misc_feature 13159..13317 /locus_tag="ClothDRAFT_3023" /note="Bacterial SH3 domain; Region: SH3_3; cl02551" /db_xref="CDD:141512" misc_feature 13438..13770 /locus_tag="ClothDRAFT_3023" /note="NlpC/P60 family; Region: NLPC_P60; cl11438" /db_xref="CDD:164223" gene 13862..16198 /locus_tag="ClothDRAFT_3024" CDS 13862..16198 /locus_tag="ClothDRAFT_3024" /inference="protein motif:TFAM:TIGR00361" /note="TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase domain protein; KEGG: dol:Dole_0767 DNA internalization-related competence protein ComEC/Rec2" /codon_start=1 /transl_table=11 /product="DNA internalization-related competence protein ComEC/Rec2" /protein_id="ZP_05428905.1" /db_xref="GI:256003919" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR004477" /db_xref="InterPro:IPR004797" /translation="MKRPLVCFSLSLMAGILCTNLTHSYLFAFLSCVVIGVIAFILLK NKDNAKFIVGGIVLFYFIGAVYYLYGYNRNLHKFEEFAGKNVVIRGYIDSAPEIKGST IRYVLKTEEIRLKEDSNQEKKIRGKILLSVQKSDEVPLFEYGREIKISGKISIPKGRT NPGGFDYRKYLNHSGISATVFVVGRNIYPQKNVKGNIFVKAGLSIRERIVNVINQSLP PQQAGLLSGMLIGYREGLSEEVEEAFSNSGLTHLMAVSGANVAFIMLPLVFIFKKLRF RQNIYNIIIIGILLLFTFITGFEPSVLRAVIMAIVILVGQILKRETDIFTSIAFAAIL LLLLNPGNLFNIGFQLSFAATISLVLFYTNLKNMLNFGFLPEFITDVLASTLAAQIGV LPITVFYFNKISLISVLSNLIVAPVVEFITIMGSLMAVLGQIHIIFSVLIGYCNNALL SFVLFVTKTTAELPYSVITVSTPSVVLVIIYYIFILFLFWYKPKYKVKLNLKYCVLAG AVSVALIAVSFLWPKGMEVVFLDVGQGDGAFIRTCSGKTILIDGGPESAGENAVVPFL LDYGVTEIDLVVVSHGHDDHYKGLLPVLENFKVRTLIIPDVDTDEGLLDAIEIARKRK ISVEKCEKDDVITLDKKTYIEVLHPREGIYFNESGINNSSLVLKLNFKDVSILFTGDI EKEAERLLCEDEVNLDADVLKVAHHGSSTSSTEEFLDSVTPDVAVISVGKNNFGHPSE EVLQRMESKGIYVLRTDISGAVVLKTYGEKIRIRPTVP" sig_peptide 13862..13936 /locus_tag="ClothDRAFT_3024" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.970) with cleavage site probability 0.725 at residue 25" misc_feature 14135..16141 /locus_tag="ClothDRAFT_3024" /note="DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361" /db_xref="CDD:161839" misc_feature 14543..15283 /locus_tag="ClothDRAFT_3024" /note="Competence protein; Region: Competence; cl00471" /db_xref="CDD:163839" misc_feature 15356..16183 /locus_tag="ClothDRAFT_3024" /note="Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446" /db_xref="CDD:186000" gene 16389..17438 /locus_tag="ClothDRAFT_3025" CDS 16389..17438 /locus_tag="ClothDRAFT_3025" /inference="protein motif:PFAM:PF05343" /note="PFAM: peptidase M42 family protein; peptidase M18 aminopeptidase I; peptidase M20; KEGG: geo:Geob_2180 peptidase M42 family protein" /codon_start=1 /transl_table=11 /product="peptidase M42 family protein" /protein_id="ZP_05428906.1" /db_xref="GI:256003920" /db_xref="InterPro:IPR001948" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR008007" /translation="MDYINILKDLSTYPGVSGQEDKLSGYIAKLFEKYCDSVEIDEFY NVIGIKKGIGGSGGRRIMVTAHLDEIGLMVKSIDEKGFITVSNIGGVDSKVLLAQEVV IHGKKEIYGIIGAKPPHLLTPEEIKKAVKMEDLVIDTGLSAEEVRKYVSVGDIVTFKV EPLVLQNNRFSSKSLDNRAGVVALLDIMENLTLLNHKDDVWFVATVQEEVGLRGANIA AYNISPDLAIVIDVCHGQIPGTPKESVFPVGKGPAVAVGPNLHRKYTKKMIELAKEEN IPYQIDVEPGDTGTEAWAVQVSREGIPTLLVSIPLKYMHTVIETLSIDDIKNTGRLIA RFISMTGNEMEEGLC" misc_feature 16389..17417 /locus_tag="ClothDRAFT_3025" /note="Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363" /db_xref="CDD:31554" misc_feature 16392..>16526 /locus_tag="ClothDRAFT_3025" /note="Peptidase dimerization domain; Region: M20_dimer; cl09126" /db_xref="CDD:186834" misc_feature 16572..17384 /locus_tag="ClothDRAFT_3025" /note="Peptidase dimerization domain; Region: M20_dimer; cl09126" /db_xref="CDD:186834" gene 17432..18481 /locus_tag="ClothDRAFT_3026" CDS 17432..18481 /locus_tag="ClothDRAFT_3026" /EC_number="3.2.1.4" /inference="protein motif:PRIAM:3.2.1.4" /note="PFAM: peptidase M42 family protein; KEGG: pca:Pcar_1216 putative lyase/synthase" /codon_start=1 /transl_table=11 /product="Cellulase" /protein_id="ZP_05428907.1" /db_xref="GI:256003921" /db_xref="InterPro:IPR008007" /translation="MLIKELTELNGVSGNEDEVRKFIKEEAQKYADSITEDSMGNLIC YKKGGSSKYRVMLSAHMDEVGFMVTGYDDGLIKFASIGGIDERILPGKRVLVGEKRIP GVIGSKPIHLQEKAERGNNIKLKNMYIDIGAEKKEEAEKLAPLGEYIAFYSMYTEFGD GCIKAKALDDRVGCAILLEILKERYGFDLYVCFTVQEEIGLRGAGVAAFRVNPDIAIV VEGTTCSDVPGAREHEYSTVMGNGAALTIMDRTSYSNKKLVDFMYKTAKDKNIPVQYK QTATGGNDAGKIQLTREGVVVASVSVPCRYIHSPVSVMNRRDYESCLNLVKAVLEEFD NNESLIESFKLHNVK" misc_feature 17432..18442 /locus_tag="ClothDRAFT_3026" /note="Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363" /db_xref="CDD:31554" misc_feature 17435..>17626 /locus_tag="ClothDRAFT_3026" /note="Peptidase dimerization domain; Region: M20_dimer; cl09126" /db_xref="CDD:186834" misc_feature 17549..18406 /locus_tag="ClothDRAFT_3026" /note="Peptidase dimerization domain; Region: M20_dimer; cl09126" /db_xref="CDD:186834" gene 18528..19505 /locus_tag="ClothDRAFT_3027" CDS 18528..19505 /locus_tag="ClothDRAFT_3027" /inference="protein motif:PFAM:PF05343" /note="PFAM: peptidase M42 family protein; peptidase M20; KEGG: ecr:ECIAI1_4103 putative fructose-specific phosphotransferase system protein FrvX" /codon_start=1 /transl_table=11 /product="peptidase M42 family protein" /protein_id="ZP_05428908.1" /db_xref="GI:256003922" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR008007" /translation="MFDLLKKFTGIVGVSGNEEEIREAIIEEIKECVDEIKVDTLGNL IAVKKGKGKKIMVAAHMDEIGVMVTYIDDKGFLRFSAVGGVSRYDCIGQRVKFKNGVV GAVYYEEKLEDMKNLQLSKMYIDIGARSREEALKMVNIGDVACFVGDAVLQGDTVISK ALDNRSGCAVVVKAIKELKKTDNEIYFVFTVQEEVGLRGAKTAAFSIKPDIAIAVDVT MTGDTPESHPMEVKCGGGPAIKVKDRSVICHPEVRKLLEESAKRNNIPYQLEILEAGG SDPGSIHLTAGGIPSGAISIPVRYVHSPVETASMSDINNAVKLLVEAIC" misc_feature 18528..19499 /locus_tag="ClothDRAFT_3027" /note="Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363" /db_xref="CDD:31554" misc_feature 18651..19484 /locus_tag="ClothDRAFT_3027" /note="Peptidase dimerization domain; Region: M20_dimer; cl09126" /db_xref="CDD:186834" gene 19768..20835 /locus_tag="ClothDRAFT_3028" CDS 19768..20835 /locus_tag="ClothDRAFT_3028" /inference="protein motif:TFAM:TIGR01141" /note="TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmw:Mmwyl1_1133 histidinol-phosphate aminotransferase" /codon_start=1 /transl_table=11 /product="histidinol-phosphate aminotransferase" /protein_id="ZP_05428909.1" /db_xref="GI:256003923" /db_xref="InterPro:IPR001917" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR005861" /translation="MSKYWSNIVKKISPYVPGEQPKDKKYIKLNTNENPYPPSEKVLK AISAAVNESLRLYPDPACESLRNTLAKYYGIKASEVFVGNGSDELLAFSFMAFFNPGD TIIFPDITYSFYEVYSSMFSVNYRLIPLDDEFNVPVEEFFTENDGIILANPNAPTGKA LPLESIRKILEKNDDKVVIIDEAYVDFGARSSVPLIKEFENLLVIQTLSKSRALAGLR VGFALGSEQLIEGLDRVKNSINSYTLDRLALIGAEEAIKDHEYFCEIRDKIINTREWV SKKLSSMGFKVIESKANFIFISHPKINGRLLFEKYKENNILVRHFNSPRIDNFLRVSI GSDEEMNIFCEKTKEIIESLN" misc_feature 19792..20796 /locus_tag="ClothDRAFT_3028" /note="histidinol-phosphate aminotransferase; Region: hisC; TIGR01141" /db_xref="CDD:162223" misc_feature 19846..20814 /locus_tag="ClothDRAFT_3028" /note="Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609" /db_xref="CDD:99734" misc_feature order(20020..20028,20098..20100,20230..20232,20317..20319, 20386..20388,20392..20397,20419..20421) /locus_tag="ClothDRAFT_3028" /note="pyridoxal 5'-phosphate binding site; other site" /db_xref="CDD:99734" misc_feature order(20029..20031,20128..20130,20296..20298,20413..20421, 20509..20511,20518..20520) /locus_tag="ClothDRAFT_3028" /note="homodimer interface; other site" /db_xref="CDD:99734" misc_feature 20395..20397 /locus_tag="ClothDRAFT_3028" /note="catalytic residue; other site" /db_xref="CDD:99734" gene 20946..22571 /locus_tag="ClothDRAFT_3029" CDS 20946..22571 /locus_tag="ClothDRAFT_3029" /inference="protein motif:PFAM:PF07521" /note="PFAM: RNA-metabolising metallo-beta-lactamase; beta-lactamase domain protein; KEGG: dal:Dalk_2789 RNA-metabolising metallo-beta-lactamase" /codon_start=1 /transl_table=11 /product="RNA-metabolizing metallo-beta-lactamase" /protein_id="ZP_05428910.1" /db_xref="GI:256003924" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR011108" /translation="MKITFLGAAKTVTGSCFFVETASTKFLVDCGMFQGYSKNNALNE EEFPFNVEELDYIFLTHAHIDHSGRIPRIYIKGFRGQIIATKATVELCAIMLPDSGHI QEYENEWTNRKRLRAGKPPVEPLYTYQDAVNCLELFRKVSYDEVIKINDEIRVRFRDA GHILGSAIIEMWINERGEEIKIVFSGDLGNKDIPILRDPSIIESADYLVIESTYGNRL HNERVDKAEYFLNLINSTIEKGGNVIIPSFAVGRTQELIYELNKKKEVYDEKLKMLFA TPVYIDSPMAISATEVFRNNLDCYDEEAREYIENGDNPLDFPGLQFTRTAEESKALNE RKESSIIIAASGMCEAGRIRHHLKHNLWRKDSTIIFVGYQAEGTLGRRLLDGAKKVRL FGEEISVEARIEMIEGFSGHADKEGLLKWIERFNRKPKKIFIVHGEEDAMIEFSEEIN RRFNIETVIPSRGESFILNAHNVIAIDEKVRPDNSFRILQVVEKLENIKEEVEELSYI LKSDLKQDKTDLELDELMAKLKNIEKSILEALK" misc_feature 20946..22349 /locus_tag="ClothDRAFT_3029" /note="Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236" /db_xref="CDD:31429" misc_feature 20970..21569 /locus_tag="ClothDRAFT_3029" /note="Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446" /db_xref="CDD:186000" misc_feature 21702..22094 /locus_tag="ClothDRAFT_3029" /note="Beta-Casp domain; Region: Beta-Casp; pfam10996" /db_xref="CDD:151443" misc_feature 22128..22265 /locus_tag="ClothDRAFT_3029" /note="RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521" /db_xref="CDD:148882" gene 22727..24238 /locus_tag="ClothDRAFT_3030" CDS 22727..24238 /locus_tag="ClothDRAFT_3030" /inference="protein motif:TFAM:TIGR00813" /note="TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: afw:Anae109_1759 Na+ symporter" /codon_start=1 /transl_table=11 /product="SSS sodium solute transporter superfamily" /protein_id="ZP_05428911.1" /db_xref="GI:256003925" /db_xref="InterPro:IPR001734" /translation="MFMKFLFLALFVAVMIGVGIYSRKKINNEQDFLLGGRKMGPWIS AFAYGTTYFSAVIFIGYAGKNGWNFGISAVWIGIANAVLGCLLSWLVLAKRTRKMTHD LNVSTMPDFFEKRYDSKGLKIVSSIIIFVFLVPYSASVYQGLSYLIEKTIAEPLAATF GITISFEAIMLVMAALTGIYLLLGGYIATAINDLIQGIIMILGIILMVAFVVNHENVG GIAEGLSRLSQIPDVGEGLVKPFGPQPLSLLSLVILTSLGTWGLPQMIHKFYAVKDDD SIKKATIVSTIFATLISGGAYFIGVFGRLFVTLDEIGGDLDRIVPTMLEKALPDYLMG IVIILVLSASMSTLSSLVLVSSSAISMDLVKGVFFPKMKSEKVMVLMRILCALFVAFS FVVGVRPSSILTLMSLSWGTVAGSFLAPFLYGLYWKGTTKAGAWAGMIVGFLCSVGGS MIFGLKNAPNVGAAAMLISLIVVPVVSLFTAKLPNAHINMIYGEEDSKQKLAS" misc_feature 22727..24115 /locus_tag="ClothDRAFT_3030" /note="Sodium:solute symporter family; Region: SSF; cl00456" /db_xref="CDD:186007" gene 24475..26280 /locus_tag="ClothDRAFT_3031" CDS 24475..26280 /locus_tag="ClothDRAFT_3031" /inference="protein motif:TFAM:TIGR03336" /note="TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: geo:Geob_2794 indolepyruvate ferredoxin oxidoreductase, alpha subunit" /codon_start=1 /transl_table=11 /product="indolepyruvate ferredoxin oxidoreductase, alpha subunit" /protein_id="ZP_05428912.1" /db_xref="GI:256003926" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR011766" /db_xref="InterPro:IPR017721" /translation="MLELCDKIEIILFHYLWLDGGLLMKKLMLGNEAVARGAYEAGVR VATAYPGTPSTEITESIAKYDEVYCEWSPNEKVALEVAIGSAIAGGRAICSMKHVGLN VAADPLFTVSYTGVNAGLVIMVADDPGMHSSQNEQDSRMYAKAAKVPMVEPADSRECK EYVKAAFEISEKFDTPVIFRLSTRISHSQSVVEIGEREDVPLKEYKKDPEKYVMMPAM ARKRHVAVESRMAALAEFSNTTPLNRIEWGSTDIGVITSGIAYQYAREAFGDVSYLKL GMIYPLPDKLIKEFSEKVKVLYVIEELEPFFEEHIRKLGIKVIGKDLLPVTGEYSANL IREKVFGKQIGGKKIEGVQVPVRPPVMCPGCPHRGMFYVLNKLKLTVSGDIGCYTLGA LPPTQAMDTCICMGASIGAAHGMEKARGREFRTKTVAILGDSTFVHSGITGLIDVVYN KGNSTVIILDNSITGMTGHQHNPTTGFTIKGEPTKQVDLVKLCNAVGIDRVKVVDPFN IKEFEKTVKEEIEADEPSVIISQRPCALLKHVKFEGPHRIVIEKCRKCKMCMRIGCPA IVDMGDHIEINDALCVGCRLCSKVCNFDAIEKAGE" misc_feature 24565..26262 /locus_tag="ClothDRAFT_3031" /note="indolepyruvate ferredoxin oxidoreductase, alpha subunit; Region: IOR_alpha; TIGR03336" /db_xref="CDD:163218" misc_feature 24565..25023 /locus_tag="ClothDRAFT_3031" /note="Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034" /db_xref="CDD:132917" misc_feature order(24607..24612,24628..24630,24640..24642,24649..24651, 24679..24690,24712..24717,24721..24729,24736..24738, 24742..24744,24793..24795,24802..24804,24814..24816, 24859..24864,24895..24900) /locus_tag="ClothDRAFT_3031" /note="dimer interface; other site" /db_xref="CDD:132917" misc_feature order(24607..24612,24619..24624,24628..24630,24646..24651, 24679..24690,24712..24717,24721..24729,24736..24738, 24742..24744,24793..24795,24802..24804) /locus_tag="ClothDRAFT_3031" /note="PYR/PP interface; other site" /db_xref="CDD:132917" misc_feature order(24622..24624,24697..24699) /locus_tag="ClothDRAFT_3031" /note="TPP binding site; other site" /db_xref="CDD:132917" misc_feature order(24628..24630,24853..24855) /locus_tag="ClothDRAFT_3031" /note="substrate binding site; other site" /db_xref="CDD:132917" misc_feature 25540..26076 /locus_tag="ClothDRAFT_3031" /note="TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the...; Region: TPP_IOR_alpha; cd02008" /db_xref="CDD:48171" misc_feature order(25687..25689,25768..25779,25855..25857,25861..25863) /locus_tag="ClothDRAFT_3031" /note="TPP-binding site; other site" /db_xref="CDD:48171" gene 26283..26858 /locus_tag="ClothDRAFT_3032" CDS 26283..26858 /locus_tag="ClothDRAFT_3032" /inference="protein motif:TFAM:TIGR03334" /note="TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: geo:Geob_2795 indolepyruvate ferredoxin oxidoreductase" /codon_start=1 /transl_table=11 /product="indolepyruvate ferredoxin oxidoreductase, beta subunit" /protein_id="ZP_05428913.1" /db_xref="GI:256003927" /db_xref="InterPro:IPR002869" /db_xref="InterPro:IPR017719" /translation="MKKCNIMIVGVGGQGTLLASRIIGNVALKQNYDVKVSEVHGMSQ RGGSVVTYVKIGDKVYSPIIEKGEADIIMAFEMLEALRWAEYLKEDGKLLVNEQKINP MPVIIGKEKYPENIMQMLKENYKNVISLDALKIARECKNIKAVNTVLIGLLAKVLEID KEVWIESIKEVVPSKAVDVNLKAFEEGYSRG" misc_feature 26283..26849 /locus_tag="ClothDRAFT_3032" /note="Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546" /db_xref="CDD:186072" misc_feature 26283..26849 /locus_tag="ClothDRAFT_3032" /note="2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537" /db_xref="CDD:181462" gene 26968..28269 /locus_tag="ClothDRAFT_3033" CDS 26968..28269 /locus_tag="ClothDRAFT_3033" /EC_number="6.2.1.30" /inference="protein motif:PRIAM:6.2.1.30" /note="KEGG: sfu:Sfum_1683 phenylacetate--CoA ligase" /codon_start=1 /transl_table=11 /product="Phenylacetate--CoA ligase" /protein_id="ZP_05428914.1" /db_xref="GI:256003928" /translation="MKYWNPSCECMSRDEMTKLQTERLIETVKRVYHNVPLYREKMQK KGIEPGDIKTLDDLKKLPFTYKDDLRDTYPYGMFAAPLSEIVRIHASSGTTGKPTVVG YTRKDIDTWSEVTARTLVSAGADKNSLIQVAYGYGLFTGGLGIHYGAERIGASVIPIS GGNTKRQIQIMKDFGTTILACTPSYALYMAEVMEELGIKKEDLKLKAGVFGAEQWSEN MRKEIEERLGIIAIDIYGLSEVIGPGVSTECYCKCGLHVQEDHFIPEIIDPETGEVLP PGSKGELVFSTITKEGIPLLRYRTRDISSLNYEKCECGRTTVRMSKVSGRTDDMLIIR GVNVFPSQIESVLLEFGDTAPHYLLIVDRVDNLDVLEIWVEMNQQLFSDQVKKIEDSE KKIRKAIEETLGISATVKLVEPKTIERSEGKAKRVIDKRRF" misc_feature 26992..28260 /locus_tag="ClothDRAFT_3033" /note="Acyl-protein synthetase, LuxE; Region: LuxE; cl10450" /db_xref="CDD:186997" gene 28324..28755 /locus_tag="ClothDRAFT_3034" CDS 28324..28755 /locus_tag="ClothDRAFT_3034" /inference="protein motif:PFAM:PF01842" /note="PFAM: amino acid-binding ACT domain protein; KEGG: gsu:GSU1736 ACT domain-containing protein" /codon_start=1 /transl_table=11 /product="amino acid-binding ACT domain protein" /protein_id="ZP_05428915.1" /db_xref="GI:256003929" /db_xref="InterPro:IPR002912" /translation="MLVKQISVFLENKSGRLAEVTRILGNNNIDISALSIADTTDFGI LRLIVNDPETAEKVLKDNGFTVSCCDVIAISVPDKPGGLAKVLSVLEPESIGIEYLYA FVGKAENEALVILRIDSPEKAVELLEKAGVKVLDSKTVYKL" misc_feature 28324..28752 /locus_tag="ClothDRAFT_3034" /note="ACT domain-containing protein [General function prediction only]; Region: COG4747" /db_xref="CDD:34362" misc_feature 28330..28524 /locus_tag="ClothDRAFT_3034" /note="N-terminal ACT domain of a novel protein composed almost entirely of two tandem ACT domains; Region: ACT_Bt0572_1; cd04908" /db_xref="CDD:153180" misc_feature 28534..28728 /locus_tag="ClothDRAFT_3034" /note="C-terminal ACT domain of a novel protein composed of just two ACT domains; Region: ACT_Bt0572_2; cd04882" /db_xref="CDD:153154" gene 28789..30087 /locus_tag="ClothDRAFT_3035" CDS 28789..30087 /locus_tag="ClothDRAFT_3035" /inference="protein motif:PFAM:PF00004" /note="PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: geo:Geob_3463 AAA ATPase central domain protein" /codon_start=1 /transl_table=11 /product="AAA ATPase central domain protein" /protein_id="ZP_05428916.1" /db_xref="GI:256003930" /db_xref="InterPro:IPR001984" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR011704" /translation="MDIKKEPLAYRMRPRTLEEFYGQEEIVGEGKLLNRMIKADRISS IILYGPPGTGKTSLARIIANSTKANFEKLNAVTAGVADIKRIVSDTQNPILNPKGRTV LFIDEIHRFNKSQQDALLPYVEDGTIILVGATTENPFFEVNKALISRSSVFMLKPLGS DAIKKIIRNALTDKERGLGNMDIEIEEDALNFLADICDGDARIALNALELAVLTSPVG SDGKFHIDIQLIEECIQKKAARYDKSGEEHYDNISAFIKSMRGSDPDAAVFYLARALY AGEDPMFLARRIMICAAEDVGMANPAALQVAVAAAQAVHMVGMPEARIILSQAAIMVA TSPKSNSCYVAIDRALDDVKNKRTGEVPMHLRNAVTSGMKELGYGKGYKYAHDYPGNI VDQDYLPQEIKGTVYYNPSANGYELKIKEWLEKRRNKREI" misc_feature 28807..30081 /locus_tag="ClothDRAFT_3035" /note="recombination factor protein RarA; Reviewed; Region: PRK13342" /db_xref="CDD:183986" misc_feature 28849..29235 /locus_tag="ClothDRAFT_3035" /note="The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes...; Region: AAA; cd00009" /db_xref="CDD:99707" misc_feature 28933..28956 /locus_tag="ClothDRAFT_3035" /note="Walker A motif; other site" /db_xref="CDD:99707" misc_feature order(28936..28959,29104..29106,29191..29193) /locus_tag="ClothDRAFT_3035" /note="ATP binding site; other site" /db_xref="CDD:99707" misc_feature 29092..29109 /locus_tag="ClothDRAFT_3035" /note="Walker B motif; other site" /db_xref="CDD:99707" misc_feature 29233..29235 /locus_tag="ClothDRAFT_3035" /note="arginine finger; other site" /db_xref="CDD:99707" misc_feature 29569..30072 /locus_tag="ClothDRAFT_3035" /note="MgsA AAA+ ATPase C terminal; Region: MgsA_C; cl13440" /db_xref="CDD:175421" gene complement(30247..30411) /locus_tag="ClothDRAFT_3036" CDS complement(30247..30411) /locus_tag="ClothDRAFT_3036" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428917.1" /db_xref="GI:256003931" /translation="MIKFITENLANIIISAVLICLAVLAIVKIIKDRKKGSCSCGCSG CPQSQICHKD" sig_peptide complement(30334..30411) /locus_tag="ClothDRAFT_3036" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.692) with cleavage site probability 0.638 at residue 26" gene complement(30408..32573) /locus_tag="ClothDRAFT_3037" CDS complement(30408..32573) /locus_tag="ClothDRAFT_3037" /inference="protein motif:TFAM:TIGR00437" /note="TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; KEGG: ppr:PBPRB1904 ferrous ion transport protein B" /codon_start=1 /transl_table=11 /product="ferrous iron transport protein B" /protein_id="ZP_05428918.1" /db_xref="GI:256003932" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR003373" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR011619" /db_xref="InterPro:IPR011640" /db_xref="InterPro:IPR011642" /translation="MSIRIALAGNPNSGKTTMFNDLTGSNQYVGNWPGVTVEKKEGRL KGHKDVILTDLPGIYSLSPYTPEEIVSRNYLINEKPDAIIDIVDGANIERNLYLTTQL TEMGIPVVIALNMIDIVRKKGDNIDIKKLSEKFGCEVVETSALKGTGSKEAVSKAIAL AKQKAKMTPRHKFSKPVEDSLTEISSCIKDRVSPDLLRWYSIKLFERDQKVLEELSLD DATKARIENIIAKCEKQLDDDSESIITNERYKYIVDAIKDCYVRKNTSRDTISDKIDK VVTNRWLAFPIFAAVIFLVYFISVTTVGGWATEWVNDVLFGEIIPTAVESFLESVNCA DWLSSLIVDGIIAGVGSVLGFLPQMIVLFLCLSLLEDCGYMARIAFIMDRIFRKFGLS GKSFIPIIIGTGCGVPGIMASRTIESEEDRKLTIMTTTFIPCSAKLPIISLIAGAFFP GSVWVAPSVYFIGIAAIICSGIILKKTKALSGNPSPFVMELPAYHVPGVKNVALNIWD KTKSFIKKAGTIIFLASTLVWFLSNFNWRLQMVDASDSMLAGLGNIVAPLFIPLGWGT WEAAVATLTGLAAKENVVGTFGVLYGFHEVAEDGAEIWGNLQASFTALSAYSLLVFNL LCAPCFAAIGAIRREMKNAKWTLIAVGYQTGLAYAVSLCIYQFGMLFTGHGFNIFTAV AIVVFAGFVYLLLRRPDNKDSKNSSTKKISRALLGGAKL" misc_feature complement(30561..32573) /locus_tag="ClothDRAFT_3037" /note="Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370" /db_xref="CDD:30719" misc_feature complement(32085..32555) /locus_tag="ClothDRAFT_3037" /note="Ferrous iron transport protein B (FeoB) subfamily. E. coli has an iron(II) transport system, known as feo, which may make an important contribution to the iron supply of the cell under anaerobic conditions. FeoB has been identified as part of this...; Region: FeoB; cd01879" /db_xref="CDD:133280" misc_feature complement(32526..32549) /locus_tag="ClothDRAFT_3037" /note="G1 box; other site" /db_xref="CDD:133280" misc_feature complement(order(32139..32147,32223..32225,32229..32234, 32523..32534,32538..32540)) /locus_tag="ClothDRAFT_3037" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133280" misc_feature complement(32457..32471) /locus_tag="ClothDRAFT_3037" /note="Switch I region; other site" /db_xref="CDD:133280" misc_feature complement(32466..32468) /locus_tag="ClothDRAFT_3037" /note="G2 box; other site" /db_xref="CDD:133280" misc_feature complement(32403..32414) /locus_tag="ClothDRAFT_3037" /note="G3 box; other site" /db_xref="CDD:133280" misc_feature complement(order(32334..32339,32349..32405)) /locus_tag="ClothDRAFT_3037" /note="Switch II region; other site" /db_xref="CDD:133280" misc_feature complement(32223..32234) /locus_tag="ClothDRAFT_3037" /note="G4 box; other site" /db_xref="CDD:133280" misc_feature complement(32139..32147) /locus_tag="ClothDRAFT_3037" /note="G5 box; other site" /db_xref="CDD:133280" misc_feature complement(31230..31520) /locus_tag="ClothDRAFT_3037" /note="Nucleoside recognition; Region: Gate; cl00486" /db_xref="CDD:186029" misc_feature complement(31047..31211) /locus_tag="ClothDRAFT_3037" /note="Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664" /db_xref="CDD:148974" misc_feature complement(30654..31034) /locus_tag="ClothDRAFT_3037" /note="Nucleoside recognition; Region: Gate; cl00486" /db_xref="CDD:186029" gene complement(32647..32868) /locus_tag="ClothDRAFT_3038" CDS complement(32647..32868) /locus_tag="ClothDRAFT_3038" /inference="protein motif:PFAM:PF04023" /note="PFAM: FeoA family protein; KEGG: afw:Anae109_4104 FeoA family protein" /codon_start=1 /transl_table=11 /product="FeoA family protein" /protein_id="ZP_05428919.1" /db_xref="GI:256003933" /db_xref="InterPro:IPR007167" /translation="MFSLRDAKCGQTVKVVKLHGTGALKRRIMDMGITRGCEIYIHKV APLGDPIQINVRGYELSLRKSAAEMIEVE" misc_feature complement(32650..32862) /locus_tag="ClothDRAFT_3038" /note="FeoA domain; Region: FeoA; cl00838" /db_xref="CDD:186215" gene 33189..33581 /locus_tag="ClothDRAFT_3039" CDS 33189..33581 /locus_tag="ClothDRAFT_3039" /inference="protein motif:PFAM:PF02742" /note="PFAM: iron dependent repressor; SMART: iron dependent repressor; KEGG: dat:HRM2_42740 TroR" /codon_start=1 /transl_table=11 /product="iron (metal) dependent repressor, DtxR family" /protein_id="ZP_05428920.1" /db_xref="GI:256003934" /db_xref="InterPro:IPR001367" /translation="MKIQESAENYLETILILRQRIGQVRSIDIVNEMNFSKPSISYAM KQLRENGYISMDESGYITLTEKGLEIAERVYERHKVLTDYLVSLGVDEDVAKADACRI EHVISPMSFEMIKKAYKEILENKQAKKE" misc_feature 33201..33347 /locus_tag="ClothDRAFT_3039" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" misc_feature 33261..33536 /locus_tag="ClothDRAFT_3039" /note="Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529" /db_xref="CDD:128802" misc_feature 33378..>33512 /locus_tag="ClothDRAFT_3039" /note="Iron dependent repressor, metal binding and dimerization domain; Region: Fe_dep_repr_C; pfam02742" /db_xref="CDD:145737" gene complement(33658..34686) /locus_tag="ClothDRAFT_3040" CDS complement(33658..34686) /locus_tag="ClothDRAFT_3040" /EC_number="5.3.1.23" /inference="protein motif:TFAM:TIGR00512" /note="KEGG: gsu:GSU3379 aIF-2BI family translation initiation factor; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related" /codon_start=1 /transl_table=11 /product="translation initiation factor, aIF-2BI family" /protein_id="ZP_05428921.1" /db_xref="GI:256003935" /db_xref="InterPro:IPR000649" /db_xref="InterPro:IPR005251" /db_xref="InterPro:IPR011559" /translation="MKPLEYCNGVLKLLDQTLLPGEQKIVELKNYIEVADAIKNMIVR GAPAIGVTAAYGVAIASKAINTDSKEEFFAELAKVCDIIKSTRPTAVNLFWAVDRVYS RAVSNRDKTIEEIKKLIEEEAYLMEKEDIESNRSIGRFGNELIKENWTILTHCNAGAL ATCDYGTALGVIRAAHESGKNIQVFADETRPYLQGARLTAWELMQDNIPVTLICDNMA GHFMKEGLIDCVIVGADRIALNGDTANKIGTYSLAVLAKENNIPFYVAAPTTTIDFSI ETGEQIPIEERSPAEITHIKGIRIAPEGVKVRNPAFDVTPNKYISAIITEKGIIYPPY DENIKKYR" misc_feature complement(33664..34683) /locus_tag="ClothDRAFT_3040" /note="Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182; cl00348" /db_xref="CDD:185927" misc_feature complement(33691..34560) /locus_tag="ClothDRAFT_3040" /note="Initiation factor 2 subunit family; Region: IF-2B; pfam01008" /db_xref="CDD:110039" gene complement(34731..35537) /locus_tag="ClothDRAFT_3041" CDS complement(34731..35537) /locus_tag="ClothDRAFT_3041" /inference="protein motif:TFAM:TIGR01694" /note="TIGRFAM: methylthioadenosine phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: similar to Chain A, Structure Of Human 5-Deoxy-5-Methylthioadenosine Phosphorylase At 1.7 A Resolution" /codon_start=1 /transl_table=11 /product="methylthioadenosine phosphorylase" /protein_id="ZP_05428922.1" /db_xref="GI:256003936" /db_xref="InterPro:IPR000845" /db_xref="InterPro:IPR001369" /db_xref="InterPro:IPR010044" /translation="MNYKADIGVFGGSGFYSFLENVEEIEMETPYGKPSDKIAIATYE GKRIAFLPRHGKNHQFPPHMIPYRANLYAMKKLGVKKILAPTSSGSLRADIKPGDFVI CDQFVDRTTGRKDTFYDGPVTKHISSAHPYCPELRKIAIQVGKDLGITTHEKGTVVVI QGPRFSTVAESRWFSKMGWDVINMTQYPEVYLARELGICYANIALITDYDAGLEGRDD IEPVTEEAVLKVFAENNEKVKNMLFEVIKRIDLENSNCTCCNVDLSGLDL" misc_feature complement(34755..35528) /locus_tag="ClothDRAFT_3041" /note="Phosphorylase superfamily; Region: PNP_UDP_1; cl00303" /db_xref="CDD:185889" gene 35806..36444 /locus_tag="ClothDRAFT_3042" CDS 35806..36444 /locus_tag="ClothDRAFT_3042" /inference="protein motif:TFAM:TIGR02890" /note="TIGRFAM: sporulation protein, yteA family; PFAM: zinc finger DksA/TraR C4-type; KEGG: gme:Gmet_3278 TraR/DksA family transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, TraR/DksA family" /protein_id="ZP_05428923.1" /db_xref="GI:256003937" /db_xref="InterPro:IPR000962" /db_xref="InterPro:IPR014240" /translation="MDDSKKEFFRQLLVEEKKNIERTINLMEEHGISKQNVESADELS GYDNHPAELGTQLFQTELNNALKVHEERLLEDINEALTKMDKGSFGKCELCGKEIDEE RLEALPYTRLCIDCENAKESSDVNLDRQRPVEELIWDAPFGRKYLNKQEDDENEGMDQ FNDLVKYGSSDTPQDMGGYYDFDEYYTNELDKQGIVDIMDNISNEEYKKQLP" misc_feature 35830..36306 /locus_tag="ClothDRAFT_3042" /note="Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755" /db_xref="CDD:186174" gene 37125..41930 /locus_tag="ClothDRAFT_3043" CDS 37125..41930 /locus_tag="ClothDRAFT_3043" /inference="protein motif:PFAM:PF02927" /note="PFAM: glycoside hydrolase family 9 domain protein Ig domain protein; PKD domain containing protein; cellulosome protein dockerin type I; glycoside hydrolase family 9; SMART: PKD domain containing protein; KEGG: scl:sce1498 putative endoglucanase A, secreted" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 9 domain protein Ig domain protein" /protein_id="ZP_05428924.1" /db_xref="GI:256003938" /db_xref="InterPro:IPR000601" /db_xref="InterPro:IPR001701" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR004197" /translation="MAKRRLSLLLVLAIMFTMVVPQISASAETVAPEGYRKLLDVQIF KDSPVVGWSGSGMGELETIGDTLPVDTTVTYNGLPTLRLNVQTTVQSGWWISLLTLRG WNTHDLSQYVENGYLEFDIKGKEGGEDFVIGFRDKVYERVYGLEIDVTTVISNYVTVT TDWQHVKIPLRDLMKINNGFDPSSVTCLVFSKRYADPFTVWFSDIKITSEDNEKSAPA IKVNQLGFIPEAEKYALVTGFAEELAVSEGDEFAVINAADNSVAYTGKLTLVTEYEPL DSGEKILKADFSDLTVPGKYYISIEGLDNSPKFEIGEGIYGPLVVDAARYFYYQRQGI ELEEPYAQGYPRKDVTPQDAYAVFASGKKDPIDITKGWYDAGDFGKYVNAGATGVSDL FWAYEMFPSQFVDGQFNIPESGNGVPDILDEARWELEWMLKMQDKESGGFYPRVQSDN DENIKSRIIRDQNGCTTDDTACAAGILAHAYLIYKDIDPDFAQECLDAAINAWKFLEK NPENIVSPPGPYNVYDDSGDRLWAAASLYRATGEEVYHTYFKQNYKSFAQKFESPTAY AHTWGDMWLTAFLSYLKAENKDQEVVDWIDTEFGIWLENILTRYENNPWKNAIVPGNY FWGINMQVMNVPMDAIIGSQLLGKYSDRIEKLGFGSLNWLLGTNPLRFSFVSGYGEDS VKGVFSNIYNTDGKQGIPKGYMPGGPNAYEGAGLSRFAAKCYTRSTGDWVANEHTVYW NSALVFMAAFANQGSEVNPGPAPEPGVTPNPTEPAKVVDIRIDTSAERKPISPYIYGS NQELDATVTAKRFGGNRTTGYNWENNFSNAGSDWLHYSDTYLLEDGGVPKGEWSTPAS VVTTFHDKALSKNVPYTLITLQAAGYVSADGNGPVSQEETAPSSRWKEVKFEKGAPFS LTPDTEDDYVYMDEFVNYLVNKYGNASTPTGIKGYSIDNEPALWSHTHPRIHPDNVTA KELIEKSVALSKAVKKVDPYAEIFGPALYGFAAYETLQSAPDWGTEGEGYRWFIDYYL DKMKKASDEEGKRLLDVLDVHWYPEARGGGERICFGADPRNIETNKARLQAPRTLWDP TYIEDSWIGQWKKDFLPILPNLLDSIEKYYPGTKLAITEYDYGGGNHITGGIAQADVL GIFGKYGVYLATFWGDASNNYTEAGINLYTNYDGKGGKFGDTSVKCETSDIEVSSAYA SIVGEDDSKLHIILLNKNYDQPTTFNFSIDSSKNYTIGNVWAFDRGSSNITQRTPIVN IKDNTFTYTVPALTACHIVLEAAEPVVYGDLNNDSKVNAVDIMMLKRYILGIIDNINL TAADIYFDGVVNSSDYNIMKRYLLKAIEDIPYVPENQAPKAIFTFSPEDPVTDENVVF NASNSIDEDGTIAYYVWDFGDGYEGTSTTPTITYKYKNPGTYKVKLIVTDNQGASSSF TATIKVTSATGDNSKFNFEDGTLGGFTTSGTNATGVVVNTTEKAFKGERGLKWTVTSE GEGTAELKLDGGTIVVPGTTMTFRIWIPSGAPIAAIQPYIMPHTPDWSEVLWNSTWKG YTMVKTDDWNEITLTLPEDVDPTWPQQMGIQVQTIDEGEFTIYVDAIDW" sig_peptide 37125..37208 /locus_tag="ClothDRAFT_3043" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.528 at residue 28" misc_feature 37755..38033 /locus_tag="ClothDRAFT_3043" /note="E or 'early' set of sugar utilizing enzymes which may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end; Region: E_set; cl09101" /db_xref="CDD:176832" misc_feature 38070..39371 /locus_tag="ClothDRAFT_3043" /note="Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959" /db_xref="CDD:186543" misc_feature 40998..41060 /locus_tag="ClothDRAFT_3043" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 41232..41450 /locus_tag="ClothDRAFT_3043" /note="polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146" /db_xref="CDD:29065" gene 42497..44626 /locus_tag="ClothDRAFT_3044" CDS 42497..44626 /locus_tag="ClothDRAFT_3044" /inference="protein motif:PFAM:PF00759" /note="PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; cellulosome protein dockerin type I; KEGG: hch:HCH_02464 cellulase" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 9" /protein_id="ZP_05428925.1" /db_xref="GI:256003939" /db_xref="InterPro:IPR001701" /db_xref="InterPro:IPR001956" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MKKTLCFVLTLAMLTAFILPQGIVSAAGSYNYAEALQKAIYFYE CQQAGPLPEWNRVEWRGDATMNDEVLGGWYDAGDHVKFNLPMAYSAAMLGWALYEYGD DIEASGQRLHLERNLAFALDYLVACDRGDSVVYQIGDGAADHKWWGSAEVIEKEMTRP YFVGKGSAVVGQMAAALAVGSIVLKNDTYLRYAKKYFELADATRSDSTYTAANGFYSS HSGFWDELLWASTWLYLATGDRNYLDKAESYIPKLNRQNQTTDIEYQWAHCWDDCHYG AMILLARATGKEEYHKFAQMHLDWWTPQGYNGKRVAYTPGGLAHLDTWGPLRYATTEA FLAFVYADSINDPALKQKYYNFAKSQIDYALGSNPDNRSYVVGFGNNPPQRPHHRTAH GTWLDKRDIPEKHRHVLYGALVGGPGRDDSYEDNIEDYVKNEVACDYNAGFVGALCRL TAEYGGTPLANFPPPEQRDDEFFVEAAINQASDHFTEIKALLNNRSSWPARLIKDLSY NYYMDLTEVFEAGYSVDDIKVTIGYCESGMDVEISPITHLYDNIYYIKISYIDGTNIC PIGQEQYAAELQFRIAAPQGTKFWDPTNDFSYQGLTRELAKTKYMPVFDGATKIFGEV PGGFEPVPSPSPTPAQYKVGDLNGDGVVNSTDSVILKRHIIKFSEITDPVKLKAADLN GDGNINSSDVSLMKRYLLRIIDKFPVE" sig_peptide 42497..42577 /locus_tag="ClothDRAFT_3044" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.969 at residue 27" misc_feature 42512..43846 /locus_tag="ClothDRAFT_3044" /note="endoglucanase; Region: PLN02420" /db_xref="CDD:178040" misc_feature 42587..43837 /locus_tag="ClothDRAFT_3044" /note="Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959" /db_xref="CDD:186543" misc_feature 43910..44170 /locus_tag="ClothDRAFT_3044" /note="Cellulose binding domain; Region: CBM_3; pfam00942" /db_xref="CDD:109977" misc_feature 44429..44488 /locus_tag="ClothDRAFT_3044" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 44534..44596 /locus_tag="ClothDRAFT_3044" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 44840..46252 /locus_tag="ClothDRAFT_3045" CDS 44840..46252 /locus_tag="ClothDRAFT_3045" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hps:HPSH_01720 cell division inhibitor (MinD)" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428926.1" /db_xref="GI:256003940" /translation="MKLYLVAGSKSDMLKRSLEENQDIEVVYIANSFEEALNHLIRNS LDFDSMLLMDAGIVENTESFTDTLNTLRELMNSSYPNITIKFITKDPVYLNNYNNIVS GDDRFEVYFVDNVRIPISYIQEVCLKNQNKKSSRIQPVEKQVADDSSKTSDEKLTQTL TAKSKTIFGVRLPFFSKSNASEEKLENGETNNSIIGSYVQPKQKISLVSKDFRKVIVV TGCRGAGATSTAANLAIESSAQGLSTILVDMDIQYRGVNLYFPKFGDEVEYNPDLSYS LVRCVIKPDSYDINSCRINDNLFVTTLAYSISSKDKLLEIIDLKKLSAFINFLRLKFN VVLIDMPISTLSKYSQLLTQIDSIALCVNNNLYSVISTVRTVEDLFVKEDLVLFTVKS RPVLTKYNEANRHNGKTFTPELACKIICELGGYNSDLTPAGIVPYSREFDLQIDSGQK ITSTNKVYKNHYFTILKNLL" misc_feature 45344..46057 /locus_tag="ClothDRAFT_3045" /note="ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489" /db_xref="CDD:30835" misc_feature 45482..>45637 /locus_tag="ClothDRAFT_3045" /note="Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras...; Region: Ras_like_GTPase; cl10444" /db_xref="CDD:186996" gene 46441..47316 /locus_tag="ClothDRAFT_3046" CDS 46441..47316 /locus_tag="ClothDRAFT_3046" /inference="protein motif:PFAM:PF08666" /note="PFAM: SAF domain protein" /codon_start=1 /transl_table=11 /product="SAF domain protein" /protein_id="ZP_05428927.1" /db_xref="GI:256003941" /db_xref="InterPro:IPR013974" /translation="MDINSIKSIKPGNQLPKKLLAIFVSVAVIIGSFIYLNSVNDSAK DTVDIVVVKASGGIPANTLITKDNIGKYSIIRKEFNDDMITYDKVDSILNKYSLYYLR NGAPIYYDQLTDEKPRDTEWLYDLEENYEVLTIKYDYLECGGSILRPGDLVRVRVTYT EEIPSSDGMMYGGSKKVKKTEILFDSIRVKDLINSSGRSIYEVLKEVFKLSEKDRREV MKSRDFMQSIKAESLLLAATEEQVNKFAKFKSQQDAVFTFTILSRNGNDEVFDQLPVV EKEVESWITESEAKD" gene 47286..48122 /locus_tag="ClothDRAFT_3047" CDS 47286..48122 /locus_tag="ClothDRAFT_3047" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: fph:Fphi_0495 septum formation inhibitor-activating ATPase" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428928.1" /db_xref="GI:256003942" /translation="MDNRERSEGLELKSLLEKLSPRDKIYNEMETNKIIDNVIGFIPA SDCADSSILLVNLAVAIAQKGFNTCILDAKVFYPNIYKLLDCEANAAGKGLIRICRSD KVDIRDVINETKYKNLYLLSPSPSDPMEDYFDFQLDDVDRVITTLKETFDFVLIDIPN NPPLEFCISSVKNCNVGFFIWSERIDCPQNTSRFLEFVGSLGIGVSKLMNVILNNLYG VKFDKTIIEDMKLKLIAEFPFVSGAIDLSLEGRVYIADSLIINKKYKESMNSLVNILT KK" misc_feature 47436..48119 /locus_tag="ClothDRAFT_3047" /note="Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455" /db_xref="CDD:30803" misc_feature 47436..>47534 /locus_tag="ClothDRAFT_3047" /note="Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras...; Region: Ras_like_GTPase; cl10444" /db_xref="CDD:186996" gene 48144..49589 /locus_tag="ClothDRAFT_3048" CDS 48144..49589 /locus_tag="ClothDRAFT_3048" /inference="protein motif:PFAM:PF00437" /note="PFAM: type II secretion system protein E; KEGG: bba:Bd0111 Flp pilus assembly protein TadA" /codon_start=1 /transl_table=11 /product="type II secretion system protein E" /protein_id="ZP_05428929.1" /db_xref="GI:256003943" /db_xref="InterPro:IPR001482" /translation="MLSRSTVSELQKKAKYIHRTNTSGSKLTSMTFEECLKQCQQYIS NVATNYYRRIEDPAKKREMTERYIIDYVETQKPEVEGFEELSALRNALIDEITQYGPI TDAMEDPLIDEIRANGPQQIFVEKKGRTEIWDKCFTDREHMERIIAKLIGVSKVRLTP RTPMVNARTIEGYRVNATHADISPYGNPAFVVRKFKKYTLTPEEMIKEKSFSVNMYKL LSLIPKANLSWMTAGPTGSGKTTLNEVLIKHIDPLCRIITIENPAEYRLLRYKNDDPN ERVINDVLQYECVPDDDDSSPATMENLLINAMRQSPHWIGPGELRSPGEFETALRAAQ TGHYFFTTLHAEGDQEAIYRFLTAYLIKSKEPAELALRNICTAVKFVIFQEKLADGTR KVTSISEVRGSEGLKPIINQIYKFIPEDVDEDPVTGQIRAIVGKHKRVGRISDELVDR MMKAGIKKSKFEFLTRPVDPDEEEVYDIDAL" misc_feature 48303..49409 /locus_tag="ClothDRAFT_3048" /note="Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962" /db_xref="CDD:34569" misc_feature 48747..49331 /locus_tag="ClothDRAFT_3048" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature order(48840..48845,48855..48863) /locus_tag="ClothDRAFT_3048" /note="Walker A motif; other site" /db_xref="CDD:29986" misc_feature order(48843..48845,48855..48863,48915..48917,48921..48926, 49095..49100) /locus_tag="ClothDRAFT_3048" /note="ATP binding site; other site" /db_xref="CDD:29986" misc_feature 49083..49097 /locus_tag="ClothDRAFT_3048" /note="Walker B motif; other site" /db_xref="CDD:29986" gene 49579..50556 /locus_tag="ClothDRAFT_3049" CDS 49579..50556 /locus_tag="ClothDRAFT_3049" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428930.1" /db_xref="GI:256003944" /translation="MLFNVLFSVAIGLVILYILNVVLDLRLLNDLKKLVSYIVDSIAN HNTKKYLERIKRSKIVKTNDNIISKYNRLVENIIFDYNLPLTLEGFNSFISILFAILV LIVVLFLKDITLSALVSISLLVGAITYFTMRSRNLKAAKIESIMDAEDLICPLARDGV LVAIKKVLESDEYINADIRPFFVQFVENCENYGYSFRRAMEILNRQLGPKFDNFAKKA VIFEYNERKGMADIFLDIVEENAALREINARKNRIFKKMNMNFIMKTALIVIFVAYSM TVPELRIFMLESTAGRFILTMTIVAICLSFARCQALQADIGSFGGDNKW" gene 50550..51434 /locus_tag="ClothDRAFT_3050" CDS 50550..51434 /locus_tag="ClothDRAFT_3050" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: apa:APP7_0591 tight adherence protein C" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428931.1" /db_xref="GI:256003945" /translation="MVILSKLCALAAIIYLVFTLIYPLFKPMTRKRKEHSRDFIKRKR NQKKVEKYLYFKDIVLRRLSNKFFLSDIKRNELNFLIKRLDLKITPEEIRLKQILYVI GAVGISLIAMNINTLIGYGCLIFVVLGWLYPVDELEKMIEKKNNNILADFPSFYNMLY YQYARSINIYLADVVKDFLPNANEDMAAELEVFLDNIEYGEEYALKQLKKRVPLRHII KFCDIMETRLRGYDNISQMTYLKNELYDLRVMSLEDELHRREQKNARMQFVLIVVLAI YIVIYYYFMFVDAIRMFS" gene 51496..51711 /locus_tag="ClothDRAFT_3051" CDS 51496..51711 /locus_tag="ClothDRAFT_3051" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428932.1" /db_xref="GI:256003946" /translation="MNKKSKKDVLKNSIKKFLKDERGEFGVKQIAYTVAVIVVVGLVL AILRDQMEGIVTTIWNFLWEKIQDLMG" gene 51769..52371 /locus_tag="ClothDRAFT_3052" CDS 51769..52371 /locus_tag="ClothDRAFT_3052" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428933.1" /db_xref="GI:256003947" /translation="MAGFAKSLVIVLIVCVVFLITTNFIFFFPWYMTLAYETYNLSTL AAQHNYIDRDEAQMILDNLNKKPFFKENPVTFDDIDGETEPGKLQRGEQFTVSITAKY PIRMDMGIVNIRRDWPVTFSVETTCLYYDKNLDPLYKSDDLIFDEPIYDEPIYYDEPA YDDPSYTGPTEDEPLYDEPAYDDPTHAVPTEGAPPFEEPI" gene 52390..52875 /locus_tag="ClothDRAFT_3053" CDS 52390..52875 /locus_tag="ClothDRAFT_3053" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428934.1" /db_xref="GI:256003948" /translation="MRNLAIAILIIVVASMLFQPFFEMVEIFAEKAQIDSAVESAAKS ARLTGFKLSDIRDLEKKFNFDMDSEDENFISVFCDVFAATLNLEFLYVIDNKAYFKSN NERYNDFVVEFQYDKDYPDRCHVIVTTNYKFKRNYLKQFVGDNSFELVRERTLFARME N" gene complement(52906..54993) /locus_tag="ClothDRAFT_3054" CDS complement(52906..54993) /locus_tag="ClothDRAFT_3054" /inference="protein motif:PFAM:PF00069" /note="PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: CNK1; NimA-related protein kinase 1" /codon_start=1 /transl_table=11 /product="serine/threonine protein kinase" /protein_id="ZP_05428935.1" /db_xref="GI:256003949" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR001245" /db_xref="InterPro:IPR002290" /db_xref="InterPro:IPR006118" /db_xref="InterPro:IPR008271" /db_xref="InterPro:IPR017441" /db_xref="InterPro:IPR017442" /translation="MLVSSDDYIKKYEPLWGAWFVESFIGEGSYGKVYKIYKEEWGFK YQSALKFISIPTQEQHREALATIGNDKNSLEQYFESAVKNIVNEIHMMYTLRGNTNIV SYEDHLVQKSSNRFGWDILIRMEYLTTLNKYILKNGLTRVGVVNLALDICSALEICEQ KRIIHRDIKDENIFVTSDGKFKLGDFGIAKELTRLSLASSIRGTPLYMAPEVYRGKPY DSRSDLYSLGIVMYKLLNHGRFPFMPPYPQELKYKDSETALDKRLSGEAITPPMLAGE KLSQFILKICAYNPDERYASATEAKKALYEILSEMSSEERSYWVVPPAAADEAEKADD TEKVIDTVILPQSDIANQNEKNTDDECMDTVLLEVPKPPQAPKKTLDRTVSIFGSLLR REMVYNLTGNHSGNILNGGLVCTQGSWLYFSNAGCDFNIYKVKLDGSDLQRINNDESW FLNVCGNWIYYTDPNNDDNIFRIDLEGNGKTRLNTDRSWDITVCGEWIYYINESDGYK LYKIKTDGTERTKLNNDFTQSLFLKDDWLYYSNKSDGGKIYKINTLGKGRTRIVNDEA SYINVYGDYIFYCNKSDGFKLYRASIDGRSKNKLNDDISYNINVSNGWIYYCNKSDGG SIYRIRTEGTDKTKLNNENSEFINLANEHIYYCSKLNSGKLYSISLGGSNRTKISMDK NHNEDDDEGWFYL" misc_feature complement(<54268..54921) /locus_tag="ClothDRAFT_3054" /note="Protein Kinases, catalytic domain; Region: PKc_like; cl09925" /db_xref="CDD:186871" misc_feature complement(order(54376..54387,54430..54432,54439..54441, 54472..54474,54478..54483,54487..54489,54493..54495, 54601..54603,54607..54609,54613..54624,54688..54690, 54844..54846,54850..54852,54895..54897,54907..54921)) /locus_tag="ClothDRAFT_3054" /note="active site" /db_xref="CDD:173623" misc_feature complement(order(54439..54441,54472..54474,54478..54483, 54487..54489,54493..54495,54607..54609,54613..54624, 54688..54690,54844..54846,54850..54852,54895..54897, 54907..54921)) /locus_tag="ClothDRAFT_3054" /note="ATP binding site; other site" /db_xref="CDD:173623" misc_feature complement(54088..54909) /locus_tag="ClothDRAFT_3054" /note="Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220" /db_xref="CDD:128516" misc_feature complement(order(54376..54387,54430..54432,54481..54483, 54487..54489,54493..54495,54601..54603,54607..54609, 54907..54909)) /locus_tag="ClothDRAFT_3054" /note="substrate binding site; other site" /db_xref="CDD:173623" misc_feature complement(order(54376..54387,54424..54444)) /locus_tag="ClothDRAFT_3054" /note="activation loop (A-loop); other site" /db_xref="CDD:173623" misc_feature complement(53428..>53706) /locus_tag="ClothDRAFT_3054" /note="tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800" /db_xref="CDD:163025" gene complement(55116..55946) /locus_tag="ClothDRAFT_3055" CDS complement(55116..55946) /locus_tag="ClothDRAFT_3055" /EC_number="3.1.3.16" /inference="protein motif:PRIAM:3.1.3.16" /note="KEGG: mno:Mnod_3050 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein" /codon_start=1 /transl_table=11 /product="protein serine/threonine phosphatase" /protein_id="ZP_05428936.1" /db_xref="GI:256003950" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR014045" /translation="MYSEKNIILRATAATHIGYVRSANEDNFYLNGIFFSPSMTEKTI LFDINEADSFFLFAVSDGLGGEIRGDEASLTAMRELKKAHNLIKNNNNGNINSCAVNI NSYIKNTNNLIYNMSVQYGARMGTTFAALLICGDRAQTFNLGDSRIYHVTDGEIVQLT KDHTEAERLVRLGILSPEEASKSASKNMLYKFLGIPTKEGIIEADISESFFVKKGDVF LLCTDGLTNMVENERIKDVINTENTPSKAASKLINEALENGGFDNITCIVVKIEDILS " misc_feature complement(55134..55910) /locus_tag="ClothDRAFT_3055" /note="Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143" /db_xref="CDD:29062" misc_feature complement(55176..55889) /locus_tag="ClothDRAFT_3055" /note="Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331" /db_xref="CDD:128626" misc_feature complement(order(55161..55163,55278..55280,55758..55766, 55869..55874,55884..55886)) /locus_tag="ClothDRAFT_3055" /note="active site" /db_xref="CDD:29062" gene complement(56082..56330) /locus_tag="ClothDRAFT_3056" CDS complement(56082..56330) /locus_tag="ClothDRAFT_3056" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428937.1" /db_xref="GI:256003951" /db_xref="InterPro:IPR000626" /translation="MNSVIVTVKCKNKKDTRDLELPTDIPAKHLSSLIAYALRLDDDL TSVTSKFHLYAEPLGRVLRDDETLEDAGVWDGSILTIL" gene complement(56482..56784) /locus_tag="ClothDRAFT_3057" CDS complement(56482..56784) /locus_tag="ClothDRAFT_3057" /inference="protein motif:PFAM:PF06013" /note="PFAM: protein of unknown function DUF909" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF909" /protein_id="ZP_05428938.1" /db_xref="GI:256003952" /db_xref="InterPro:IPR010310" /translation="MASVIRITPEQVRSAAVKIGKKTSETTNFLNSIQREIDSLKSIW EGKAAEAYVEQFMALRKELETKLNQCLSDLERSLTSVANALEQADKDVAAKLRSGS" misc_feature complement(56518..56772) /locus_tag="ClothDRAFT_3057" /note="Proteins of 100 residues with WXG; Region: WXG100; cl02005" /db_xref="CDD:154701" gene complement(56921..61600) /locus_tag="ClothDRAFT_3058" CDS complement(56921..61600) /locus_tag="ClothDRAFT_3058" /inference="protein motif:PFAM:PF01580" /note="PFAM: cell divisionFtsK/SpoIIIE; Forkhead-associated protein; SMART: Forkhead-associated protein; AAA ATPase; KEGG: pha:PSHAb0091 cell divisionFtsK/SpoIIIE domain-containing protein" /codon_start=1 /transl_table=11 /product="FHA domain containing protein" /protein_id="ZP_05428939.1" /db_xref="GI:256003953" /db_xref="InterPro:IPR000253" /db_xref="InterPro:IPR002543" /db_xref="InterPro:IPR003593" /translation="MSNKYLLHIYFDNFFKIVEIDAFNKNIISIGRSGTNDIVIDSSC IDENHCSLKKEDNQWYIYNHSKSGIFYDGSTISRKMLVPYDTYIIGNSPETMSRAAII VKPEDPYDNVVENFEIRGVSEITIGKSESCNIVYSDKLVSGEHAKIYKSIDGKYHIAD LESLNGTFLNGKKVYDSVLSQGDVIYICGYKIVFEGSFISVYHIGDRVYVNGLKAALK QTKPPYPYIQRSPRLIPEMPEGEKTIPNPPALASKPTASWISILLPPIVMSLITIITA IVGKSLYMLLSVSMTFVSVIVSISQYISQNKKFKDDIELRNKKYGEIIHSIRKELEIA REQQKKGMLIMNPDPAECIRRVETIDRRLWERTPQFKDFLSARIGIGTTPLAIKINVQ SQLLSIDSDPLMSEPQKIYDEFSQVSDIPVCVPLFHSGTAGIIGSRSEVLKNVRALII QLATFHSYEEVKIVLVYPKEEADEWEWIRWLPHVWNENRQIRFLANDKDMTHQLFSHL YDVIKEREQRTGKDKDNIPPTPVNLPHYVFILADIRLIEDEPIMNYLAHNNQALGIST IYLFDRIEYLPKDCQAIIELAPKSGHMVQRNQGSSPMPFLPDIVSIKDAEHFARRMAP IRIKELLTSVSLPSSITLLQMYSVRTVEELNVLERWKNNKSFRTLAAPLGIRTGNEIL TLDLHERGQGPHGLVAGTTGSGKSELLQSFIISLAINFHPHDVVFVLIDYKGGGMANA FLDLPHLVGTITNLGGNQTTRALVSIKSELKRRQTIFAQYGVNHIDSYQKLYHSQKAK EPLPHLVIIADEFAELKSEQPDFMRELVSTARVGRSLGVHLILATQKPAGVVDDQIWS NARFRICLKVQGPQDSQDVIKRPDAANIKQPGRAYIQVGNDEIFELFQSAWSGAGYTP DASEEITTHNEISEVAINGKRHQLYTRSASQIRKAEFTQLQAAVSHIANVAQKENIVR LKGPWLPPLPEKLYLESLLADVKGCWDGEKWTKADSWLNPVVGLLDDPENQRQVPLTV DLGKEGHLIVYGSPGYGKTTFLQTLIMSLALNYSPSDVNIYILDFGVRTLGIFSGLPH VGGTVMVDEEEKLSKLFKFLIKEMDTRKDLFSDKGVSSLTAYRDSCGETLPAIVIVID NYSAFSEMYSEYEDYLIQISREGGNLGLHIVITNSSTSSISYKLSSNFKLAVALQMAD KGDYALIVGRTNGLEPSPVNGRGLVKGNPPLEFQTALPAEGESEIERTIKIKSTIGAI SQSWTGPKAKPIPVMPEIVYYKDLITRDDVKKTIARKPLCIPLGIEENEMEPCFIDLL ETPHFLVSGDIQSGKTTFLQALAVTLALKFSPEKLDIHIFDSSSLGLYALSQLPHTKN YTNDGHNISEFAEALQQEIDNRKAELNEERIRSGGLINEKEFVLNRRLSLILIDDLND FSQYADSIVTDLFERLVKKERNLGISIIMASYTEDIGSSWDNFAKAMKDMQTGLLLGS ISDQQVFSVRLPYGTTEKAIKPGDGYLINRGRFCRVKTALLENNILKAWITQINKSYR KNNQSVE" misc_feature complement(61364..61519) /locus_tag="ClothDRAFT_3058" /note="Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062" /db_xref="CDD:153486" misc_feature complement(61016..61273) /locus_tag="ClothDRAFT_3058" /note="Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060" /db_xref="CDD:28942" misc_feature complement(order(61103..61111,61172..61177,61181..61183, 61217..61219)) /locus_tag="ClothDRAFT_3058" /note="phosphopeptide binding site; other site" /db_xref="CDD:28942" misc_feature complement(<60107..60685) /locus_tag="ClothDRAFT_3058" /note="DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674" /db_xref="CDD:31860" misc_feature complement(59057..59647) /locus_tag="ClothDRAFT_3058" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature complement(58064..58609) /locus_tag="ClothDRAFT_3058" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature complement(57203..57748) /locus_tag="ClothDRAFT_3058" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" gene complement(61806..63008) /locus_tag="ClothDRAFT_3059" CDS complement(61806..63008) /locus_tag="ClothDRAFT_3059" /inference="protein motif:PFAM:PF02922" /note="PFAM: glycoside hydrolase family 13 domain protein; KEGG: conserved hypothetical protein" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 13 domain protein" /protein_id="ZP_05428940.1" /db_xref="GI:256003954" /db_xref="InterPro:IPR004193" /translation="MKYPFYYCCDNLDIKSISVIGDFNNWDGGKNILKRHDDGTWMTE IELSPGKYRYKFLINDSILFNDPNALIYTYDDKGGTASFIIIDESNKRIINTKPASLN IESYSFLSVDKELSYCENGERKCYKDKHSSIMLKIGFSDITGLHTVNAIWYAPNNEIH EIQESVLNDGEKNENRKNEALFQININDDTIAGEWKLQIFINGSLALEDSFTVELKQP EVLDKTALDDAAMLSADLEVPDFLIEEDMQNEFEAPEFEVESNLQTNAEKEEISEEDL LGLFDDIKEIDMPEKDTSGNQKTPAPDETEMPADGNIMNLFDEIRISELKDEKAQDTE NNTESTSKEAEESDSAIDELLELREFIDSSQNSEKDSIESSGGKSGEEANEEDISDIF IDIKNRTD" misc_feature complement(62772..62966) /locus_tag="ClothDRAFT_3059" /note="E or 'early' set of sugar utilizing enzymes which may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end; Region: E_set; cl09101" /db_xref="CDD:176832" gene 63227..64975 /locus_tag="ClothDRAFT_3060" CDS 63227..64975 /locus_tag="ClothDRAFT_3060" /inference="protein motif:PFAM:PF00404" /note="PFAM: cellulosome protein dockerin type I; KEGG: ade:Adeh_2778 hypothetical protein" /codon_start=1 /transl_table=11 /product="cellulosome protein dockerin type I" /protein_id="ZP_05428941.1" /db_xref="GI:256003955" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MPKKVLCVVMIFVLFMSFTISTAAYNAEINGEVIVWNPGIKGGI PTKPVVANVKDFGAKGDGLTDDSNAFKKAVESVKDGGAVLIPSGEYLIKSKITLDKPV VLRGEGPGKTILLIDHSSDAFEVITYKRGNWVSLVGGYTRGSTELVVSDPTGFEAGKY VEIQQDNDPDVMYTLPEWNQGWAAGSVGQITKVVSIWGNKITIEEPLRITYRSELNPV IRTQGFAEYIGFEDFTVKRIDTSDTNMFFFKNAANCWIKNIHSIKPAKAHVSVTTGYR IEVRDSFFDDATNWGGGGHGYGVELGFHVSDCLIENNIFKHLRHSMMVHLGANGNVFG YNYSTQPYQSEGGNWTPADISVHGHYAYSNLFEGNIVQEITVSDYWGPSGPYNTFLRN RIESESVCLEDSSNYQNFIGNEIVNGNILWDTDNRYPHKIDPSTLFLHGNLINGSIQW NQQTQDRTIPNSYYLDSKPAFFGGINWPSTGSDRTDGTIPAKERYYGNTIPPASPTPD KPVKYGDLNGDNNVNSTDLTLLKRYLTRVINDFPHPDGSVNADVNGDGKINSTDYSAM IRYILRIIDKFPAEKS" sig_peptide 63227..63307 /locus_tag="ClothDRAFT_3060" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.720 at residue 27" misc_feature 63359..>63523 /locus_tag="ClothDRAFT_3060" /note="Probable polygalacturonase At3g15720; Region: PLN03003; cl14103" /db_xref="CDD:187227" misc_feature 64769..64828 /locus_tag="ClothDRAFT_3060" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 64877..64939 /locus_tag="ClothDRAFT_3060" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 65241..65426 /locus_tag="ClothDRAFT_3061" CDS 65241..65426 /locus_tag="ClothDRAFT_3061" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428942.1" /db_xref="GI:256003956" /translation="MGEREIFEQINDVLRENGYNTRINGLMDLTHFLNEKRDTDSLVY DKVRELYAQFMMGIGMW" gene complement(65534..65776) /locus_tag="ClothDRAFT_3062" CDS complement(65534..65776) /locus_tag="ClothDRAFT_3062" /inference="protein motif:PFAM:PF07875" /note="PFAM: Coat F domain protein" /codon_start=1 /transl_table=11 /product="Coat F domain protein" /protein_id="ZP_05428943.1" /db_xref="GI:256003957" /db_xref="InterPro:IPR012851" /translation="MQDKEMVNDVLSQINSSLTGYANAIAQSSNPQLRQTLQQIRNSC ETFQYDLYKLAEQKGYYHAAQMADQSDIAQVKSLFL" misc_feature complement(65582..65773) /locus_tag="ClothDRAFT_3062" /note="Coat F domain; Region: Coat_F; cl02368" /db_xref="CDD:154876" gene complement(65793..65978) /locus_tag="ClothDRAFT_3063" CDS complement(65793..65978) /locus_tag="ClothDRAFT_3063" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428944.1" /db_xref="GI:256003958" /translation="MPQINQLELENLRHLIYSHETSAKKLEAYAQQATDPQVKQMFQK SAQDARNTKQQLMSFLN" gene 66202..67275 /locus_tag="ClothDRAFT_3064" CDS 66202..67275 /locus_tag="ClothDRAFT_3064" /inference="similar to AA sequence:KEGG:PsycPRwf_1518" /note="KEGG: prw:PsycPRwf_1518 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428945.1" /db_xref="GI:256003959" /translation="MENSRVSTFKVAATYIGTVVGAGFASGQEMLQFFAVFGLKGFWG LIVVTALFIVFGYIVMEVGRNLQSESHLQIIKHSGGKFLGPLMDWLITFFLFGALTAM IAGSGALVKQQFGINPFWGNLFMAAFTALTVLTGINGVINSISVVVPFLVTSAVGISL ASILLMPLRTNPYELVAAAESVSRNGLIGNWLWAAVLYVSYNLVLAISVLGPLGVQAK NKNAIRNGAILGGIGLGVSATAIYFAMERNFEIVRDMEIPMIYLAGSLSYILQIVYAL VLIGEIYTTAVGSLYGFSARITDINEGKAKFYIIGATLLALAASQLGFSNMVKYLYPV VGYGGVVLLACLAVTRFKLAKRA" sig_peptide 66202..66285 /locus_tag="ClothDRAFT_3064" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.793) with cleavage site probability 0.713 at residue 28" misc_feature 66229..67182 /locus_tag="ClothDRAFT_3064" /note="Uncharacterized membrane protein [Function unknown]; Region: COG3949" /db_xref="CDD:33730" gene 67369..68013 /locus_tag="ClothDRAFT_3065" CDS 67369..68013 /locus_tag="ClothDRAFT_3065" /inference="protein motif:PFAM:PF02965" /note="PFAM: Vitamin B12 dependent methionine synthase activation region; KEGG: sat:SYN_00095 putative cytoplasmic protein" /codon_start=1 /transl_table=11 /product="Vitamin B12 dependent methionine synthase activation region" /protein_id="ZP_05428946.1" /db_xref="GI:256003960" /db_xref="InterPro:IPR004223" /translation="MEKYTRLKFFEHIPAVPDNGMILTRLGYRKTTTILDDDYKKTLM ENINKGLMLCNTKGVFGTFKIEKRDEESVELDNGVVLKSKSLSKLLSNSMDVVLMAST VGKEIVDRIVDEINNNNASFGVVLDAVASETADAALDWMVDFINKMIRREGKKLTKMR YSPGYGDLPLSNQKLIYDVLNLERLGISITERFMLVPEKSVIAIAGVEGVGCNE" misc_feature 67657..67986 /locus_tag="ClothDRAFT_3065" /note="Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965" /db_xref="CDD:111813" gene 68006..70420 /locus_tag="ClothDRAFT_3066" CDS 68006..70420 /locus_tag="ClothDRAFT_3066" /inference="protein motif:PFAM:PF02574" /note="PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: sat:SYN_02703 5-methyltetrahydrofolate--homocysteine methyltransferase" /codon_start=1 /transl_table=11 /product="homocysteine S-methyltransferase" /protein_id="ZP_05428947.1" /db_xref="GI:256003961" /db_xref="InterPro:IPR000489" /db_xref="InterPro:IPR003726" /db_xref="InterPro:IPR003759" /db_xref="InterPro:IPR006158" /translation="MNKKDFLDFLNQNILILDGATGTELQKRGMPGGVCPEMWVIENP DVIMDIQKDYINAGSNAVYTCTFGGNRIKLSEFGLGDKVVEINKKLAQLSRKAAGEKG LVAGDLAPTGRFVRPFGDMPFEEAVDVYKEQVKGLLEGGVDFFVIETMMDIQEARAAL LAVKESCDLPVCVSMTFDESGRTLTGTDSVSALIILQSLGADVVGCNCSTGPQDMIKI IREMKPYAKVPLLAKPNAGLPKLIDGKTRFDMEPEEFGSYIKEFVEAGVNLLGGCCGT SPVYIEQIRKNIEGLKPIPPQPKEICAVASARKTVFVDANEPVVVVGERINPTGKKKL QEELRQGMTSLVRQFAVEQVEKGADILDVNVGMPGIDEKETMVKVVELLSSITDAPLC LDSSSPEVLEAALRIYPGRALINSISAEKVKIEKLLPIAAKYGAAFILLPLGDAGVPK SAGERCKIVEEVFNEASKWGYTKKDVIVDGLVMTVSADQEAAVETLKVIEWCTQSFGC GTIVGLSNVSFGMPERAWINSAFLAMAIGYGLTMAILNPSSDTLMSIKMASDVLKVKD RNSKKYIEHFAALKSDKPQVVEKKDTASPVEKVYDAVVKGDRENIRKYIDDALKDGTE PSIIVDKYLIPAITHVGDLYDRKEYFLPQLIQSAETMKEAFGILEPLLKKEPVDEKGN KVKVILATVKGDIHDIGKNIVGLMLRNYGFEVYDLGKDVSAEEIVKKAKETNAPIIGL SALMTTTMLEMREVVSLVRQEGLNAKIMIGGAVVNADYAKEIGADGYSEDAYGAVKLA SKLAGI" misc_feature 68006..68875 /locus_tag="ClothDRAFT_3066" /note="Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646" /db_xref="CDD:30991" misc_feature 68045..68917 /locus_tag="ClothDRAFT_3066" /note="Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) [Amino acid transport and metabolism]; Region: MHT1; cl14105" /db_xref="CDD:187229" misc_feature 68960..69652 /locus_tag="ClothDRAFT_3066" /note="Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH). DHPS, a...; Region: Pterin_binding; cl00219" /db_xref="CDD:185837" misc_feature order(68984..68986,69185..69187,69248..69250,69254..69256, 69326..69328,69440..69442,69542..69544,69554..69556, 69635..69637,69641..69643) /locus_tag="ClothDRAFT_3066" /note="substrate binding pocket; other site" /db_xref="CDD:29544" misc_feature order(69485..69490,69593..69595,69605..69607,69617..69619) /locus_tag="ClothDRAFT_3066" /note="dimer interface; other site" /db_xref="CDD:29544" misc_feature 69548..69556 /locus_tag="ClothDRAFT_3066" /note="inhibitor binding site; inhibition site" /db_xref="CDD:29544" misc_feature 69740..70408 /locus_tag="ClothDRAFT_3066" /note="Predicted cobalamin binding protein [General function prediction only]; Region: COG5012" /db_xref="CDD:34617" misc_feature 69800..70402 /locus_tag="ClothDRAFT_3066" /note="B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070" /db_xref="CDD:30208" misc_feature order(70082..70102,70109..70111,70220..70228,70232..70240, 70319..70321,70367..70369,70376..70378,70385..70387) /locus_tag="ClothDRAFT_3066" /note="B12 binding site; other site" /db_xref="CDD:30208" misc_feature 70091..70093 /locus_tag="ClothDRAFT_3066" /note="cobalt ligand; other site" /db_xref="CDD:30208" gene 71005..73095 /locus_tag="ClothDRAFT_3067" CDS 71005..73095 /locus_tag="ClothDRAFT_3067" /inference="protein motif:TFAM:TIGR02487" /note="TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: dol:Dole_2570 anaerobic ribonucleoside triphosphate reductase" /codon_start=1 /transl_table=11 /product="anaerobic ribonucleoside-triphosphate reductase" /protein_id="ZP_05428948.1" /db_xref="GI:256003962" /db_xref="InterPro:IPR005144" /db_xref="InterPro:IPR012833" /translation="MVTKISKRDGRIEKYQPEKITWAIFKAATACGGSDFGRAEELCR QVNEILNKQFKDRIPGVEDIQDIVEKVLIENGHAKTAKAYILYREKRKSARDLNALVG ATINMFSDYLGDRDWHIKENANTQKSVNGLNNYVREVFTKKYWLYEIYPAEVREAHEN GDCHIHDLGFFGPYCAGWDLRQLLLDGFGGVEGKVESRPAKHLRSFLGQIVNSTFTTQ GETAGAQAWSSFDTYCAPFIRYDNMTYEQVKQCLQEFVFNINVPTRVGFQCPFSNLTF DIKVPNTLKDEPVIIGGKYMDATYKEFQKEMDMFNTAFCDVMLEGDAKGRVFTFPIPT INITKDFDWDNPVVDKFMKITCKYGIPYFANYINSDLSPEDAVSMCCRLRIDTTELRK RGGGLFGSNPLTGSIGVFTINLPRIGYLSKSESEFKERLWKIANIGKTSLEIKRKIIE QQSEKGLYPYSTHYLRHVKQRTGEYWFNHFNTIGIVGMNEALKNFMGKDITTPEGQKF AIDIMHYLRDILLEFQNETGHFYNLEATPAEGTSYRLAKIDKERYPDIITAGRDIPYY TNSTQLPVDYTDDIFETLELQDELQSLYTGGTVQHLYLGESIEDVNVCKNLIRKVFTN YKMPYISITPTFSICKDHGYIKGEHFKCPECGNDTEVWSRVTGYLRPVANYNIGKKEE YFNRKKFKLAEKVS" misc_feature 71005..73002 /locus_tag="ClothDRAFT_3067" /note="anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK08270" /db_xref="CDD:181341" misc_feature 71014..71280 /locus_tag="ClothDRAFT_3067" /note="ATP cone domain; Region: ATP-cone; pfam03477" /db_xref="CDD:146230" misc_feature 71365..73017 /locus_tag="ClothDRAFT_3067" /note="Class III ribonucleotide reductase; Region: RNR_III; cd01675" /db_xref="CDD:153084" misc_feature order(71494..71496,71500..71505,71593..71607,71617..71619, 71626..71631,71638..71640,71734..71736,72616..72627, 72634..72636) /locus_tag="ClothDRAFT_3067" /note="effector binding site; other site" /db_xref="CDD:153084" misc_feature order(71527..71529,71674..71676,71815..71817,72142..72147, 72226..72228,72610..72612,72619..72621) /locus_tag="ClothDRAFT_3067" /note="active site" /db_xref="CDD:153084" misc_feature order(72919..72921,72928..72930,72958..72960,72967..72969) /locus_tag="ClothDRAFT_3067" /note="Zn binding site; other site" /db_xref="CDD:153084" misc_feature 72994..73008 /locus_tag="ClothDRAFT_3067" /note="glycine loop; other site" /db_xref="CDD:153084" gene 73092..73781 /locus_tag="ClothDRAFT_3068" CDS 73092..73781 /locus_tag="ClothDRAFT_3068" /inference="protein motif:TFAM:TIGR02495" /note="TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; KEGG: sat:SYN_03523 pyruvate formate-lyase activating enzyme" /codon_start=1 /transl_table=11 /product="anaerobic ribonucleoside-triphosphate reductase activating protein" /protein_id="ZP_05428949.1" /db_xref="GI:256003963" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR012840" /translation="MRIAGIHKNSFVDFPGKIAIVVFTPGCNMNCFYCHNKTLISGGN EEFIDNDEVLELLVKRRGFIDGVVISGGEPTLQKDLEGFLEKVKSLGYAVKLDTNGTN PHVVENLVQNGLVDYIAMDVKAPFGKYNEICRTNVDVDSIKKSIEIIKSGKVDYEFRT TVAPGLEMDDIFEIARGIEGARLYVLQKYRDVSESAVKDFRNPQFLLDAAVRIKGIVQ RVETRGVAFCA" misc_feature 73095..73661 /locus_tag="ClothDRAFT_3068" /note="anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG2; TIGR02495" /db_xref="CDD:162888" misc_feature 73152..73637 /locus_tag="ClothDRAFT_3068" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(73170..73172,73176..73178,73182..73184,73188..73196, 73299..73301,73305..73310,73383..73388,73446..73448, 73572..73574) /locus_tag="ClothDRAFT_3068" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene complement(73860..73955) /locus_tag="ClothDRAFT_3069" CDS complement(73860..73955) /locus_tag="ClothDRAFT_3069" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428950.1" /db_xref="GI:256003964" /translation="MLQRIVVVNVTKLDFVIKNYIKEIIFIYFKE" gene complement(73959..75599) /locus_tag="ClothDRAFT_3070" CDS complement(73959..75599) /locus_tag="ClothDRAFT_3070" /inference="protein motif:TFAM:TIGR00464" /note="TIGRFAM: glutamyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase class Ic; KEGG: scl:sce0573 hypothetical protein" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA synthetase" /protein_id="ZP_05428951.1" /db_xref="GI:256003965" /db_xref="InterPro:IPR000924" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR004527" /translation="MDYKKLADMLFPHITKSVSYYEDVVFPARNLSPGAKVTRLAPSP TGFIHLGNLYGAFVDERLAHQSNGVFILRIEDTDDKRKVEGAVETIISSLEFFNLKFD EGAGINGETGNYGPYFQSNRAEIYQTVAKHLVEMGRAYPCFCSEEELEEIRKQQLAEN VNTGYYGKWAVHRNLTLEEVQKHLENNESFVIRFKSMGNPEETFEIDDAIRGRLSMQV NFQDIVLLKANGIPTYHFAHVVDDHLMRVTHVVRGEEWLSTLPIHYELFTTLGWDLPV YCHTAHLMKIDNGVKRKLSKRKDPELGLEYYMQLGYHPAAVREYLMTILNSNFEEWRI QNPDSDINDFPFSLNKMSNSGALFDLDKLNDVSKNVLAKIPAEEIYEFLLKWAKEYKK EIVNLLEEHKDSVIKLLSVGRNSEKPRKDLIYCEQIFEFIKYFFDEYFAIVDKYPDNV DEEEAKKILKAYLETYDHNDDQTQWFEKIKVIATENGYAAKPKDYKKNPDMYKGHVGD VSTVIRIAIVGRSSSPDLWEIQQIMGEEKVRERIQRLL" misc_feature complement(<75177..75497) /locus_tag="ClothDRAFT_3070" /note="nucleotidyl transferase superfamily; Region: nt_trans; cl00015" /db_xref="CDD:185776" misc_feature complement(73962..75491) /locus_tag="ClothDRAFT_3070" /note="glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406" /db_xref="CDD:179296" misc_feature complement(75444..75455) /locus_tag="ClothDRAFT_3070" /note="HIGH motif; other site" /db_xref="CDD:173912" misc_feature complement(75444..75455) /locus_tag="ClothDRAFT_3070" /note="active site" /db_xref="CDD:173912" misc_feature complement(order(75444..75446,75453..75455)) /locus_tag="ClothDRAFT_3070" /note="nucleotide binding site; other site" /db_xref="CDD:173912" misc_feature complement(74481..>74921) /locus_tag="ClothDRAFT_3070" /note="catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808" /db_xref="CDD:173905" misc_feature complement(order(74718..74723,74754..74759,74832..74837, 74841..74846,74886..74888,74898..74900)) /locus_tag="ClothDRAFT_3070" /note="active site" /db_xref="CDD:173905" misc_feature complement(74709..74723) /locus_tag="ClothDRAFT_3070" /note="KMSKS motif; other site" /db_xref="CDD:173905" gene complement(75694..75768) /locus_tag="ClothDRAFT_R0020" /note="tRNA-Glu1" tRNA complement(75694..75768) /locus_tag="ClothDRAFT_R0020" /product="tRNA-Glu" gene 76110..76439 /locus_tag="ClothDRAFT_3071" CDS 76110..76439 /locus_tag="ClothDRAFT_3071" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428952.1" /db_xref="GI:256003966" /translation="MYDGFVYEDKKFFTFSKMGNTGCLISCVATAITNLNVPITPKEL NAALTEKDGFLGVDLIWYKINEAIPEVDYRYSRIFNSKTIEKDLERGLLPIVNARYHK TGELIEC" gene 76433..76564 /locus_tag="ClothDRAFT_3072" CDS 76433..76564 /locus_tag="ClothDRAFT_3072" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428953.1" /db_xref="GI:256003967" /translation="MLIVRAKEGEFIICYPLDDGTETRLLSDHGRVYAYRVTERAER" gene 76561..76860 /locus_tag="ClothDRAFT_3073" CDS 76561..76860 /locus_tag="ClothDRAFT_3073" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428954.1" /db_xref="GI:256003968" /translation="MILLKEKNVFVITGPCGVGKSTASRRLAQTLDKSCHINANLIYE MVVGRYLFPWQEVLKYIVLMADENTVRMRDGKRPPQEVMGDRAIEVFNEFKDKKN" misc_feature 76573..>76653 /locus_tag="ClothDRAFT_3073" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" gene 76835..76951 /locus_tag="ClothDRAFT_3074" CDS 76835..76951 /locus_tag="ClothDRAFT_3074" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428955.1" /db_xref="GI:256003969" /translation="MNLKIKKIDCKYILDTSCKSIEDIVLEIKREERFIMEK" gene 76983..77483 /locus_tag="ClothDRAFT_3075" CDS 76983..77483 /locus_tag="ClothDRAFT_3075" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428956.1" /db_xref="GI:256003970" /translation="MNSVKINVKYTTKDFKDFFLSTRFMGIIGKMNIAISLFFLLVIG VLVLNTIGYITINPEDTETISFLLFSVVFLSVLFTMIGLFPFFVSYFVEKRLFFRKQL QQPFNCIEVTEEKITVFNSESTFTFFWNDVYKVEELKPVFFDICVFLQQNNNSKEVFC FTGTFG" gene 77476..78150 /locus_tag="ClothDRAFT_3076" CDS 77476..78150 /locus_tag="ClothDRAFT_3076" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428957.1" /db_xref="GI:256003971" /translation="MVNFRRILYISKLDKRKLKLKNYELKKSSPDYGEVEFKTQPLSE YSEYIEENAEKNPELELDIIFEKKDILKMSFARIFSDPATIIIISIGLILFVFGILYF GSLLNPATVIVAFLAFPQFIFLPIAVSFGYNKLYKNDDNLKKSVKYIFYKDYYVIKNF AGERRIDCINIEKVVEKESCFVLHLTSKLLQIMPKKVFEEKERELKKFRQLMNEYQSC KSSVRV" gene 78233..78469 /locus_tag="ClothDRAFT_3077" CDS 78233..78469 /locus_tag="ClothDRAFT_3077" /inference="protein motif:PFAM:PF01361" /note="PFAM: 4-oxalocrotonate tautomerase; KEGG: bvi:Bcep1808_4282 4-oxalocrotonate tautomerase" /codon_start=1 /transl_table=11 /product="4-oxalocrotonate tautomerase" /protein_id="ZP_05428958.1" /db_xref="GI:256003972" /db_xref="InterPro:IPR004370" /translation="MPHVIVKLWPGRTEEQKQELANRIAKDVIETLNAPQTSVSVSIQ EVPREKWVDEVYNPDIMDKEETLYIKPGYKPENL" misc_feature 78236..78385 /locus_tag="ClothDRAFT_3077" /note="4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235" /db_xref="CDD:185852" misc_feature order(78236..78241,78344..78346) /locus_tag="ClothDRAFT_3077" /note="active site 1" /db_xref="CDD:29603" misc_feature order(78236..78256,78290..78292,78299..78304,78311..78313, 78323..78328) /locus_tag="ClothDRAFT_3077" /note="dimer interface; other site" /db_xref="CDD:29603" misc_feature order(78245..78247,78251..78253,78281..78286,78293..78298, 78305..78307,78338..78343,78347..78361,78365..78370, 78377..78385) /locus_tag="ClothDRAFT_3077" /note="hexamer interface; other site" /db_xref="CDD:29603" misc_feature order(78251..78253,78383..78385) /locus_tag="ClothDRAFT_3077" /note="active site 2" /db_xref="CDD:29603" gene 78597..78860 /locus_tag="ClothDRAFT_3078" CDS 78597..78860 /locus_tag="ClothDRAFT_3078" /inference="similar to AA sequence:KEGG:SYN_02132" /note="KEGG: sat:SYN_02132 transcriptional regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator, CopG family" /protein_id="ZP_05428959.1" /db_xref="GI:256003973" /translation="MEKENRKENRIAVIGIVIHNREESSRKVNEILSDYGNIIVGRMG VPYKEKGISVIAIIVDGTTDEIGALTGKLGNINGVKAKVALTN" misc_feature <78603..78836 /locus_tag="ClothDRAFT_3078" /note="Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864" /db_xref="CDD:31204" gene 79129..80550 /locus_tag="ClothDRAFT_3079" CDS 79129..80550 /locus_tag="ClothDRAFT_3079" /inference="protein motif:PFAM:PF06968" /note="PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sat:SYN_02133 thiamine biosynthesis protein ThiH" /codon_start=1 /transl_table=11 /product="biotin and thiamin synthesis associated protein" /protein_id="ZP_05428960.1" /db_xref="GI:256003974" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR010722" /translation="MCRYKVCKLKVGDIQMVEKVDFIKEDLIFSLLEKGKITDRNEIR EILAKARECKGISLGEVAKLLYLEDEELLEELYDVAKYIKNKIYGKRVVLFAPLYTSN ECTNNCLYCGFRHDNKELHRKTLSLEEIVEEAKAIERQGHKRLLLICGEDPRKTNVKH FTDAMEAIYKSTDIRRINVEAAPMTVEDYRELKKAGIGTYVIFQETYHRETYRIMHPV GKKANYDWRITAIDRAFEGGIDDVGVGALFGLYDYRFEVLGLLMHCMHFEEKYGVGPH TISVPRLRPALGAPLKEIPYKVTDKDFKKIVAIFRIAVPYTGIILSTRERAEFRDELL SVGVSQISAGSKTNPGGYQEDDDHADQFEISDNRSLPKVMETICQQGYIPSFCTACYR RCRTGEHFMEYAKAGDIHEFCQPNAILTFKENLMDYADEPLRKMGEEVILKALEEIED EKMKTLTIAKLEEIEKGKRDIYF" misc_feature 79165..80547 /locus_tag="ClothDRAFT_3079" /note="thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613" /db_xref="CDD:181990" misc_feature 79420..80007 /locus_tag="ClothDRAFT_3079" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(79438..79440,79444..79446,79450..79452,79456..79464, 79573..79575,79579..79584,79666..79674,79735..79737, 79864..79866,79972..79977) /locus_tag="ClothDRAFT_3079" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" misc_feature 79963..80280 /locus_tag="ClothDRAFT_3079" /note="Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149" /db_xref="CDD:157061" gene 80774..81919 /locus_tag="ClothDRAFT_3080" CDS 80774..81919 /locus_tag="ClothDRAFT_3080" /inference="protein motif:TFAM:TIGR01977" /note="TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V; KEGG: gur:Gura_2313 cysteine desulfurase family protein" /codon_start=1 /transl_table=11 /product="cysteine desulfurase family protein" /protein_id="ZP_05428961.1" /db_xref="GI:256003975" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR010969" /translation="MIYLDNAATSYPKPDRVYDEMLLCMKEYCANPGRSGHELAIKTG RAVYETREIVSRFFNIENPMRVVFTKNATEALNLAINGVLKEGDHVITTSMEHNSVLR PLKTLERNNIIELTIVWGNYFGEIDVADIERSIKKNTKMIICSLSSNVNGIIMPVKEI GKITRERGILFLVDASQGAGSIKLDVQEINADLFAVPGHKDLLGPQGVGALYVNENVE ITPIMQGGTGSRSESFYQPEIFPDMLESGTLNAPGIVGLGFGIKFIESFGVDNIRIYK HMLIKRLYEGIENLNGIKLYSLKDMDKNSGIISFNFIGVDSTKVSFMLDRIYGIASRS GLHCAPLAHETIGTKATGTVRLSVGCFNTIEEIDTTIEALREISQGL" misc_feature 80774..81904 /locus_tag="ClothDRAFT_3080" /note="Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520" /db_xref="CDD:30866" misc_feature 80777..81895 /locus_tag="ClothDRAFT_3080" /note="Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453" /db_xref="CDD:99746" misc_feature order(80987..80992,80999..81001,81062..81064,81293..81295, 81299..81304,81362..81364,81368..81373) /locus_tag="ClothDRAFT_3080" /note="pyridoxal 5'-phosphate binding pocket; other site" /db_xref="CDD:99746" misc_feature 81371..81373 /locus_tag="ClothDRAFT_3080" /note="catalytic residue; other site" /db_xref="CDD:99746" gene 82226..83332 /locus_tag="ClothDRAFT_3081" CDS 82226..83332 /locus_tag="ClothDRAFT_3081" /inference="protein motif:TFAM:TIGR01175" /note="TIGRFAM: type IV pilus assembly protein PilM; KEGG: dol:Dole_0333 type IV pilus assembly protein PilM" /codon_start=1 /transl_table=11 /product="type IV pilus assembly protein PilM" /protein_id="ZP_05428962.1" /db_xref="GI:256003976" /db_xref="InterPro:IPR005883" /translation="MLLDLFMKKTSMVCIDVGYRNIKVVEVAVKKNNNIFIENYGIVP TPPDCIKNGAIYDVDRVLSVIKSVIREQNMKAKNAKIIMSGTNIITRIYLIDKVQGES EDFTVKNSMPQFLPIDIDNYRVDYKILQTIKEKGSEKYKVFVTAVPKNILQSYVDVLQ GLDLKPLAVDIPANSTAKFFNREILTRDMDEYYSKRKYKKVESDTFAVLDFGSETTIV NFLKDRVLEFNKVILSGSSNIDEHIARELNISLQEAERLKKTYGMTPPNNLSKREHVI TYGKVSNFIERLTRQIAKCFEFYLERCYGTPISKIFIIGGGSQLSGLNQYLFSTFNVP VYPVGLLNLKGVELKKNLDKDKLNYLINAVGISL" misc_feature 82355..82771 /locus_tag="ClothDRAFT_3081" /note="Cell division protein FtsA; Region: FtsA; cl11496" /db_xref="CDD:159497" misc_feature 82841..83224 /locus_tag="ClothDRAFT_3081" /note="Cell division protein FtsA; Region: FtsA; cl11496" /db_xref="CDD:159497" gene 83588..83761 /locus_tag="ClothDRAFT_3082" CDS 83588..83761 /locus_tag="ClothDRAFT_3082" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428963.1" /db_xref="GI:256003977" /translation="MEKENTMVKSIITIIVAIILLVIVVKLVSWAVYKLLPIAIVIIA AYIVYKVVTSRKN" gene complement(83848..84447) /locus_tag="ClothDRAFT_3083" CDS complement(83848..84447) /locus_tag="ClothDRAFT_3083" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: protein serine/threonine kinase" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428964.1" /db_xref="GI:256003978" /translation="MKRYITKEDLAQLTDAQKMHLNEMWYPQKYDLAVANICTNAETE EYQQIEFVVGDVSVYHNRFVLHDLAFLNNTNSDNFSGQEASEDFDFEELDSDFDDNYD SEYDINEDSTENENFDSLYIRPTTFSKEDCLPLLSIAQMIEILDKHKSKLYDFYLLAD NGQFAVEMGSKDYNLSGYGSDFESKELCDVLWECIKLIL" gene 84660..85211 /locus_tag="ClothDRAFT_3084" CDS 84660..85211 /locus_tag="ClothDRAFT_3084" /inference="similar to AA sequence:KEGG:Dalk_2729" /note="KEGG: dal:Dalk_2729 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428965.1" /db_xref="GI:256003979" /translation="MKCPVCKNIFLEKTSLLDELYAYSCKSCGGNWMRYEDYWKWHES NPNPANKPLDIKTHLPVNDIIQAKICPDCGRILIKYRVDNRLDFYVEHCGNCNGIWFD KNEWDNIKLNNLHGQIHHFFTKPWQKRIREEAARENLQDKYIKKFGRWDYERLKEMRE WIYKQEKKNEMLSYLLDEDPYKI" misc_feature 84861..85124 /locus_tag="ClothDRAFT_3084" /note="Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3809" /db_xref="CDD:33603" gene complement(85227..85715) /locus_tag="ClothDRAFT_3085" CDS complement(85227..85715) /locus_tag="ClothDRAFT_3085" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428966.1" /db_xref="GI:256003980" /translation="MKINDKIEKMMWSIAFPGLGQLLNGQIVKGIFFMILELLINHYS NLNSIIIYSFTGNIAEAVNNANYQWLMFYPSLYLYVIWDAYKYAKGDNSPMAFLPYVF AAYLGTVGTVYSPSFNINGVLFGPVWLPLICMAIGIFAGYIIQKQICKKINLKLDHKA KK" gene 85933..88380 /locus_tag="ClothDRAFT_3086" CDS 85933..88380 /locus_tag="ClothDRAFT_3086" /inference="protein motif:PFAM:PF03639" /note="PFAM: glycoside hydrolase family 81; cellulosome protein dockerin type I; KEGG: cja:CJA_0214 glucan endo-1,3-beta-glucanase, putative, glu81A" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 81" /protein_id="ZP_05428967.1" /db_xref="GI:256003981" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR005200" /translation="MLKKKTIISLVLAAIILGSIIQPFEIANAQYYREGTGSYTVVLP PGAKVPQAEIYKTSNLQGAVPTNSWESSILWNQYSLPIYAHPLTFKFKAEGIEVGKPA LGGSGIAYFGAHKNDFTVGHSSVYTFPDARADKISDFAVDAVMASGSGSIKATLMKGS PYAYFVFTGGNPRIDFSGTPTVFYGDSGSQCLGVTINGVNYGLFAPSGSKWQGIGTGT ITCILPAGKNYFSIAVLPDNTVSTLTYYKDYAYCFVTDTKVEWSYNETESTLTTTFTA EVSVKEGTNKGTILALYPHQWRNNPHILPLPYTYSTLRGIMKTIQGTSFKTVYRYHGI LPNLPDKGTYDREALNRYINELALQADAPVAVDTYWFGKHLGKLSCALPIAEQLGNIS AKDRFISFMKSSLEDWFTAKEGETAKLFYYDSNWGTLIGYPSSYGSDEELNDHHFHYG YFLHAAAQIALRDPQWASRDNWGAMVELLIKDIANWDRNDTRFPFLRNFDPYEGHSWA SGHAGFADGNNQESSSEAINAWQAIILWGEATGNKTIRDLGIYLYTTEVEAVCNYWFD LYKDIFSPSYGHNYASMVWGGKYCHEIWWDGTNSEKHGINFLPITAASLYLGKDPNYI KQNYEEMLRECGTSQPPNWKDIQYMYYALYDPAAAKNMWNESIVPEDGESKAHTYHWI CNLDSLGLPDFSVTADTPLYSVFNKNNIRTYVVYNASSSAKKVTFSDGKVMTVGPHSM AVSTGSESEVLAGDLNGDGKINSTDISLMKRYLLKQIVDLPVEDDIKAADINKDGKVN STDMSILKRVILRNYPL" sig_peptide 85933..86016 /locus_tag="ClothDRAFT_3086" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.462 at residue 28" misc_feature 86101..87999 /locus_tag="ClothDRAFT_3086" /note="Glycosyl hydrolase family 81; Region: Glyco_hydro_81; cl02310" /db_xref="CDD:121231" misc_feature 88192..88254 /locus_tag="ClothDRAFT_3086" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 88300..88362 /locus_tag="ClothDRAFT_3086" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 88585..90300 /locus_tag="ClothDRAFT_3087" CDS 88585..90300 /locus_tag="ClothDRAFT_3087" /inference="protein motif:PFAM:PF00652" /note="PFAM: Ricin B lectin; cellulosome protein dockerin type I; SMART: Ricin B lectin; KEGG: scl:sce4015 hypothetical protein" /codon_start=1 /transl_table=11 /product="Ricin B lectin" /protein_id="ZP_05428968.1" /db_xref="GI:256003982" /db_xref="InterPro:IPR000772" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR017871" /translation="MVKKNVGLRFLSILILMALLIGNVQSFNVAAAEGVIVNGTQFKD TSGNVIHAHGGGMLKHGDYYYWYGEYRDDSNLFLGVSCYRSKDLVNWEYRGEVLSRNS APELNHCNIERPKVMYNASTGEFVMWMHWENGINYGQARAAVAYSKTPDGKFTYIRSF RPMQDTGVMDHGLPGYMSRDCNVFVDTDGKGYFISAANENMDLHLYELTPDYKNIASL KAKLFVGQQREAPCLIKRNGYYYLITSGCTGWNPNQAKYAYSKDLASGWSQLYNLGNS TTYRSQPTFIIPVQGSSGTSYLYMGDRWAGAWGGKVNDSQYVWLPLNFISDTTLELPY YDSVKIDASSGIISEYIPDTTRYKLVNKNSGKVLDVLDGSVDNAAQIVQWTDNGSLSQ QWYLVDVGGGYKKIVNVKSGRALDVKDESKEDGGVLIQYTSNGGYNQHWKFTDIGDGY YKISSRHCGKLIDVRKWSTEDGGIIQQWSDAGGTNQHWKLVLVSSPEPSPSPSPQVVK GDVNGDLKVNSTDFSMLRRYLLKIIDNFPTENGKQAADLNGDGRINSSDLTMLKRYLL MEVDL" sig_peptide 88585..88680 /locus_tag="ClothDRAFT_3087" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.951 at residue 32" misc_feature 88732..89556 /locus_tag="ClothDRAFT_3087" /note="Glycosyl hydrolase family 43; Region: GH43_6; cd08985" /db_xref="CDD:185726" misc_feature order(88744..88746,89122..89124,89269..89271) /locus_tag="ClothDRAFT_3087" /note="active site" /db_xref="CDD:185726" misc_feature 89653..90054 /locus_tag="ClothDRAFT_3087" /note="Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly...; Region: RICIN; cd00161" /db_xref="CDD:29101" misc_feature order(89689..89691,89722..89724,89728..89730,89755..89760, 89830..89832,89866..89868,89872..89874,89896..89901, 89971..89973,90010..90012,90016..90018,90040..90042) /locus_tag="ClothDRAFT_3087" /note="putative sugar binding sites; other site" /db_xref="CDD:29101" misc_feature order(89758..89766,89899..89907,90040..90048) /locus_tag="ClothDRAFT_3087" /note="Q-X-W motif; other site" /db_xref="CDD:29101" misc_feature 90112..90174 /locus_tag="ClothDRAFT_3087" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 90220..90282 /locus_tag="ClothDRAFT_3087" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene 90307..90606 /locus_tag="ClothDRAFT_3088" CDS 90307..90606 /locus_tag="ClothDRAFT_3088" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428969.1" /db_xref="GI:256003983" /translation="MQKLQIVTSYLLSYIFELARTANTQLICLTGHMQVDIYMQFDVM YSLLQSKTRTNDSVLNNLNNQKYKKINPQVQSWGFFILARFFILARFFTLTGFSY" gene complement(90616..91185) /locus_tag="ClothDRAFT_3089" CDS complement(90616..91185) /locus_tag="ClothDRAFT_3089" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428970.1" /db_xref="GI:256003984" /translation="MKKFAALLIFTVVFLLVGCGGFVPQNAGKDTALPTGTGVNKPDT AAKTAEPMTPAVSEESRIKSYNLGDIVELNNIIFIVNGTREVPENRFLSPENGNIWYA IDVSIENKSNETFNFSSMLMFTLIDGEKLTYDTALVPDLKGNVDGEITPGNSVRGEVA FEIPEDAKDLMLEIDPILYGEKVVVKLDR" sig_peptide complement(91102..91185) /locus_tag="ClothDRAFT_3089" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.577 at residue 28" misc_feature complement(90634..90993) /locus_tag="ClothDRAFT_3089" /note="Telomeric repeat-binding factor 2; Region: TRF2; pfam11611" /db_xref="CDD:152047" gene complement(91385..91462) /locus_tag="ClothDRAFT_R0019" /note="tRNA-Pro2" tRNA complement(91385..91462) /locus_tag="ClothDRAFT_R0019" /product="tRNA-Pro" gene 91596..92408 /locus_tag="ClothDRAFT_3090" CDS 91596..92408 /locus_tag="ClothDRAFT_3090" /inference="protein motif:PFAM:PF06725" /note="PFAM: 3D domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="3D domain protein" /protein_id="ZP_05428971.1" /db_xref="GI:256003985" /db_xref="InterPro:IPR010611" /translation="MLSDDVTSSTEPQKCNKINKANRIYGIIIYFLSVAIISLIVNNI IIYNWYNDTKKRFKDTFLRVQTMSEENMNLETLNETLKNEYALLKEDYDRLLNENESI KKEFEELKKRNADIERINKELVEDNIELQNTLKMAAAAGIKPQNYTEFKGLSSRSSID RGEYIGKFLGTAYTPSKEECGNDNGITNSGKPIIPGISVAVDKNYWPFGTVFYIKGLG YAVAMDTGSAIKGKYRFDFAVFDKNFANKLGANYWDVYLVKMGNGKVEDISL" misc_feature 91848..>91928 /locus_tag="ClothDRAFT_3090" /note="Homeobox associated leucine zipper; Region: HALZ; cl02577" /db_xref="CDD:154996" misc_feature 91857..>92033 /locus_tag="ClothDRAFT_3090" /note="integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752" /db_xref="CDD:163464" misc_feature 92094..>92288 /locus_tag="ClothDRAFT_3090" /note="3D domain; Region: 3D; cl01439" /db_xref="CDD:154402" gene 92588..93556 /locus_tag="ClothDRAFT_3091" CDS 92588..93556 /locus_tag="ClothDRAFT_3091" /inference="protein motif:TFAM:TIGR01933" /note="KEGG: lip:LI0675 membrane protease subunits, stomatin/prohibitin homologs; TIGRFAM: HflK protein; PFAM: band 7 protein; SMART: band 7 protein" /codon_start=1 /transl_table=11 /product="HflK protein" /protein_id="ZP_05428972.1" /db_xref="GI:256003986" /db_xref="InterPro:IPR001107" /db_xref="InterPro:IPR010201" /translation="MEAINVGGNFRKAAKLPVKLIIGAIVLVIFAILFFNSFYTVTDQ EQAVVLTFGKVTSIESAGIHFKLPYPIQSVIKVPVQMTQKLELGYRDQGDGRYVTVDE ESKMITGDFNIVKIDFFIEWKVSDPKKYLFNSEDPKNILRDSSLSAARSVVGSSTIDD VLTSGKIAIENEIKEKLIASLDAYDIGIQVLDVKIQDSEPPTEEVKQAFKNVENAKQS KETAMNEANKYRNTEIPKAQAEADRILRNAESQKQTKINEARGEVAKFLKMYEEYKNY KDVTKTRLYLEAMEEILPGITVYIEDNSSGVQKLVPLKPFDSEGGE" misc_feature 92657..93466 /locus_tag="ClothDRAFT_3091" /note="Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404" /db_xref="CDD:48216" misc_feature 92699..93529 /locus_tag="ClothDRAFT_3091" /note="HflK protein; Region: hflK; TIGR01933" /db_xref="CDD:130988" gene 93558..94427 /locus_tag="ClothDRAFT_3092" CDS 93558..94427 /locus_tag="ClothDRAFT_3092" /inference="protein motif:TFAM:TIGR01932" /note="KEGG: lip:LI0676 membrane protease subunits, stomatin/prohibitin homologs; TIGRFAM: HflC protein; PFAM: band 7 protein; SMART: band 7 protein" /codon_start=1 /transl_table=11 /product="HflC protein" /protein_id="ZP_05428973.1" /db_xref="GI:256003987" /db_xref="InterPro:IPR001107" /db_xref="InterPro:IPR010200" /translation="MIKKAVLVCTLIFALIILFSGMFIVTEGEYVCIRRFGKIIDTKD SAGLYFKMPFIDSKLTLPNKKILYNLPASNVLTKDKKDMVIDNYVIWQISDPVEFVKS IGYISEAERRIDAAVYNTVKNTMGTLEQNSIINEKLSGRGKFDKIVTDEVARQLSGYG ITVYDVKIKKLDLPVENEETVYERMISEREKIAEQYKAEGEYEANKIKNEVDKQVNII ISEAKASAQELIGEGEAEYIRILSEAYSGEKKEFYEYVKTLEAMKASLKGEKTLILPI DSPITKYFRNIDN" sig_peptide 93558..93641 /locus_tag="ClothDRAFT_3092" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.943) with cleavage site probability 0.715 at residue 28" misc_feature 93576..94424 /locus_tag="ClothDRAFT_3092" /note="FtsH protease regulator HflC; Provisional; Region: PRK11029" /db_xref="CDD:182913" misc_feature 93621..94355 /locus_tag="ClothDRAFT_3092" /note="Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405" /db_xref="CDD:48217" gene 94614..96383 /locus_tag="ClothDRAFT_3093" CDS 94614..96383 /locus_tag="ClothDRAFT_3093" /inference="protein motif:PFAM:PF03323" /note="PFAM: GerA spore germination protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="GerA spore germination protein" /protein_id="ZP_05428974.1" /db_xref="GI:256003988" /db_xref="InterPro:IPR004995" /translation="MADLKKLIKDMFVFKEPEPREEFILEEKESEKIVNVTDAHDETS EKKKKGSLRNLFSKSANSEKKDSESGKESNNTENMTCVSKNLKENVEYLKKRFSIPIN GDVVLREFDIVIKDRKIPACLIFYDGMVNGMLINLNILQPLMLLSNLDVKGKNGEKDI AEYIHKSLVTHNQVKVSHEFDEIVGEINFGGCGVFIDGIDVAYACDVKGWQHRGVDRP NNEIVIRGPQESFNEILRVNTALVRKILKDEDLVAESIEIGKRSKTPCSLLYIKDIAN ESLVNEVRRRLQNIKTDYIFDTGELEQYIEDNTLMSTPQIVATERPDRVASMLAEGKV AVIMSGSPFALVMPTTNNDFLQSAEDAYVRFPYANLLRIMRVIAIFMSLLLPGLYVAI TNYHHEMIPTDLLFAIEASRERVPFPSVVEIIIMEFAFELVREAGLRVPSPIGPTLGI IGALILGQAAVAANIVSPILIIVVAVTGIGSFAIPNFSLGFSFRILRFAYVFLAAMAG FLGITFGLFVQSIILCNAKSFGVPFMAPFGPKTKSRFQDQFFRSPIWKQEKRPDFLNT KDTQKQPKISRQWRKSEKKKGKQ" misc_feature 94878..96308 /locus_tag="ClothDRAFT_3093" /note="Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323" /db_xref="CDD:146120" gene 96417..97568 /locus_tag="ClothDRAFT_3094" CDS 96417..97568 /locus_tag="ClothDRAFT_3094" /inference="protein motif:TFAM:TIGR00912" /note="TIGRFAM: spore germination protein; PFAM: Spore germination protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="ZP_05428975.1" /db_xref="GI:256003989" /db_xref="InterPro:IPR004761" /db_xref="InterPro:IPR017871" /translation="MEGKIIFGKREAISLLIILICNQLILGFPSIMSNSVGSAGWILS IYVSILALCLFLIISKLYSAFEGKDLLDISEFAGGNIARIIVGLIVVIDSVLIISVKL REYTEHIKIISFTQSPVSFIMLFFALGMIISVHFGIEPLVRSTTIVLPIVAIGVVIVV AGSVKNFELSNIMPILGTGPYDIFVGGLPRLSIFSGIISLFFIPPFMGGYKNIKKIGV LVITISGIVLTVGVLAYLLVFPYPVSSNNVLAFFELSRVLEYGRFFQRIESVFLLTWS LAGLLYLSSGLYFVIYVFSKTFKLKYYRPLIIPFTLIIFSLSLIPESLMEIMYLDNKV IRYYAWIVAFGLPFVLLSIARLVKRKRRGMAKKWEVKPRKVSRCFWHLL" misc_feature 96501..97502 /locus_tag="ClothDRAFT_3094" /note="Transmembrane amino acid transporter protein; Region: Aa_trans; cl00524" /db_xref="CDD:186058" gene 97517..98827 /locus_tag="ClothDRAFT_3095" CDS 97517..98827 /locus_tag="ClothDRAFT_3095" /inference="protein motif:TFAM:TIGR02887" /note="TIGRFAM: germination protein, Ger(x)C family; PFAM: spore germination B3 GerAC family protein" /codon_start=1 /transl_table=11 /product="germination protein, Ger(x)C family" /protein_id="ZP_05428976.1" /db_xref="GI:256003990" /db_xref="InterPro:IPR008844" /translation="MGSKTKKSFTVLLAFIMSFSVTGCFDKREIDDLVNPIAIGFDKG SNHSVRMTLQIAIPTKVAGGGEGGGGGGGEESVSYTTVEAPSIYSGLNMINSYVSKQL NMSQIKVLVFSEELAREGIEKYINALMRGREFRPHSYVIVARGTGNAAERYLRAVEPE LESNPAKYYEMLLSAYTYTGFTANTSLTNFYKNMVSESTQPLAVLADISKFEKSDDIN MDNSSYQEKGREFPLEGDFKAGDMPKVGTIKSEVMGLAVFNGSKMVGELDGEETQLQL MLEGNFGYSYVTIPDPEAEDYVVLLNIKQNRKPKRKVEIVDEKPHIKVNIYLEADILS IQSGVNYESLEKVKILEDAAEKFFEKGFLRMLKKTAKEFKSDIAGFGKEMKGKFLTWD EWTNFNWIEKYPDSEFEVDVDLKIRRPGLMLRTYPAAGTEVGEE" sig_peptide 97517..97588 /locus_tag="ClothDRAFT_3095" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.967 at residue 24" misc_feature 97535..98782 /locus_tag="ClothDRAFT_3095" /note="Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; cl05194" /db_xref="CDD:164071" gene 98831..99007 /locus_tag="ClothDRAFT_3096" CDS 98831..99007 /locus_tag="ClothDRAFT_3096" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428977.1" /db_xref="GI:256003991" /translation="MIFILRVILAIILLWVFIKTISYGKWTWDKKNRLGAVMIFLIAL AAVILPIFAFYIRY" gene 99022..100119 /locus_tag="ClothDRAFT_3097" CDS 99022..100119 /locus_tag="ClothDRAFT_3097" /inference="protein motif:TFAM:TIGR00912" /note="TIGRFAM: spore germination protein; PFAM: Spore germination protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="ZP_05428978.1" /db_xref="GI:256003992" /db_xref="InterPro:IPR004761" /translation="MNNNTFGSHEAICLMITMISTKAILSFPNIMAKIGGSAAWIVAI YISILAIIVFYITSKLYSNFEGKDIIDIGEILGGKALKIPLGILIIVFLVALSAFYLR SFSEEMKTMSFTMSPIGFIMLFFVLGMIISAYIGFEALIRFQSIMVPISVISFTLFII ALAPSMNIDNVKPILGLGPYNIFVKGAVRIGDFAELIFLFLLPPFIKKWDIFNRVGFI GLAICAIVLTSITFTFVSIFPYPVSTDDLLPTYELARIIKFGRFFERAESILVITWAT IAFMYLSTAFYFLLHIFKKTFDLCYYQPLILPMALVIMSLSLLPKRLMDSILLEAEVF RNYIWIIAFAIPLLLLIVARALNNKKSSNSP" misc_feature 99043..99978 /locus_tag="ClothDRAFT_3097" /note="Transmembrane amino acid transporter protein; Region: Aa_trans; cl00524" /db_xref="CDD:186058" gene complement(100121..100600) /locus_tag="ClothDRAFT_3098" CDS complement(100121..100600) /locus_tag="ClothDRAFT_3098" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428979.1" /db_xref="GI:256003993" /translation="MLAETIIEISSLFVSAALLLIFVPKNKIREASVIFCFKQLITWL LGLFVAEFNLIEYPVRLFANATKASFTFEYFVYPSICVIFNLYYPERKSLFKRILYYF IYTAAITVFEVILEKYTQNIKYINWTWYYTFLSVYLTFFLSRAYFKWFFKISNNAPC" gene complement(101080..101155) /locus_tag="ClothDRAFT_R0018" /note="tRNA-Trp1" tRNA complement(101080..101155) /locus_tag="ClothDRAFT_R0018" /product="tRNA-Trp" gene 101289..102104 /locus_tag="ClothDRAFT_3099" CDS 101289..102104 /locus_tag="ClothDRAFT_3099" /EC_number="1.5.1.2" /inference="protein motif:TFAM:TIGR00112" /note="KEGG: ent:Ent638_0857 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding" /codon_start=1 /transl_table=11 /product="pyrroline-5-carboxylate reductase" /protein_id="ZP_05428980.1" /db_xref="GI:256003994" /db_xref="InterPro:IPR000304" /db_xref="InterPro:IPR004455" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR011128" /translation="MSNRIGFIGAGNMGGAMITSIAQSGIIPAENILVFDVDRDKLSV LREKTGITITDSALETVRKSDIIILAVKPNMVKAVLNDIKPAVDNNKILVSVAVGIPI KFYKEMLGENIKFIRTMPNTPALVGEGMTLMCCDKNVDEKEAEQVKKIFECFGKVEFL EEKLMSEVTAVTSSSPAYVFMFIEAMADAAVLSGIPRNLAYKLSAQAVLGAAKMVLET GKHPGELKDQVCSPAGTTIEAVRSLEKNRFRYAIIEAMSECTKKALEIGKMYD" misc_feature 101289..102092 /locus_tag="ClothDRAFT_3099" /note="pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880" /db_xref="CDD:183357" sig_peptide 101289..101363 /locus_tag="ClothDRAFT_3099" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.736) with cleavage site probability 0.487 at residue 25" misc_feature 101295..102095 /locus_tag="ClothDRAFT_3099" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" gene 102218..102661 /locus_tag="ClothDRAFT_3100" CDS 102218..102661 /locus_tag="ClothDRAFT_3100" /EC_number="3.1.26.4" /inference="protein motif:PRIAM:3.1.26.4" /note="PFAM: ribonuclease H; KEGG: bid:Bind_2333 ribonuclease H" /codon_start=1 /transl_table=11 /product="Ribonuclease H" /protein_id="ZP_05428981.1" /db_xref="GI:256003995" /db_xref="InterPro:IPR002156" /translation="MKKVSIYTDGACSGNPGDGGWGAILIYGNHEKEVSGFEKDTTNN RMELVAAINALKMLKEPCEVDLYSDSAYLVNGFLQNWVEKWKKNGWKTSNKEEVKNME LWQELDRLSNIHKIRWIKVKGHSDNEYNNRCDKLATDEIKKNSKK" misc_feature 102233..102628 /locus_tag="ClothDRAFT_3100" /note="RNase H (RNase HI) is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a not sequence-specific manner. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. RNase H knockout mice lack...; Region: RnaseH; cd06222" /db_xref="CDD:119393" misc_feature order(102242..102244,102356..102358,102422..102424, 102617..102619) /locus_tag="ClothDRAFT_3100" /note="active site" /db_xref="CDD:119393" misc_feature order(102242..102253,102341..102349,102356..102358, 102422..102424,102575..102577) /locus_tag="ClothDRAFT_3100" /note="RNA/DNA hybrid binding site; other site" /db_xref="CDD:119393" gene 102682..103230 /locus_tag="ClothDRAFT_3101" CDS 102682..103230 /locus_tag="ClothDRAFT_3101" /inference="protein motif:PFAM:PF00293" /note="PFAM: NUDIX hydrolase; KEGG: tbd:Tbd_0232 hypothetical protein" /codon_start=1 /transl_table=11 /product="NUDIX hydrolase" /protein_id="ZP_05428982.1" /db_xref="GI:256003996" /db_xref="InterPro:IPR000086" /translation="MNYEEKTVSKKHIYSGNIISVECVNVLLPNGKEASRDVVLHPGA SVVIPINDNNEIYMVRQYRKPVEKELLELPAGKLDKGEDPEVCARRELKEETGLEADK IKHILSFYSGPGFTNEILHVYAAVGLHEGEACADEDEFISTKKFPINKLVEMVLNNEI TDAKSIIGILLAEKIVKGEIKI" misc_feature 102802..103206 /locus_tag="ClothDRAFT_3101" /note="ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as...; Region: ADPRase_NUDT5; cd03424" /db_xref="CDD:72882" misc_feature order(102802..102804,102808..102810,102859..102861, 102865..102867,102871..102873,102886..102888, 103003..103014,103018..103020,103024..103038, 103096..103101,103105..103107,103144..103149, 103171..103173,103183..103185,103192..103194, 103204..103206) /locus_tag="ClothDRAFT_3101" /note="dimer interface; other site" /db_xref="CDD:72882" misc_feature order(102811..102813,102868..102870,102910..102912, 102952..102954,102964..102966,103033..103035) /locus_tag="ClothDRAFT_3101" /note="ADP-ribose binding site; other site" /db_xref="CDD:72882" misc_feature order(102868..102870,102904..102912,102952..102954, 102964..102966,103033..103035,103096..103098) /locus_tag="ClothDRAFT_3101" /note="active site" /db_xref="CDD:72882" misc_feature order(102907..102918,102922..102975) /locus_tag="ClothDRAFT_3101" /note="nudix motif; other site" /db_xref="CDD:72882" misc_feature order(102952..102954,102964..102966,103096..103098) /locus_tag="ClothDRAFT_3101" /note="metal-binding site" /db_xref="CDD:72882" gene 103441..104097 /locus_tag="ClothDRAFT_3102" CDS 103441..104097 /locus_tag="ClothDRAFT_3102" /inference="protein motif:TFAM:TIGR02831" /note="TIGRFAM: stage II sporulation protein M; PFAM: protein of unknown function DUF95 transmembrane" /codon_start=1 /transl_table=11 /product="stage II sporulation protein M" /protein_id="ZP_05428983.1" /db_xref="GI:256003997" /db_xref="InterPro:IPR002798" /db_xref="InterPro:IPR014196" /translation="MEIILRGDKMIKKIHEVLISHIKNNINTYFFLFLMYIGGISAGA FTVNGLSSLQRNELINYFQGFLELFEHQWVDSNEILRISIIDNARLVIALWVLGVTII GIPFIYLLVGIRGFITGFTSGFIIYIMGFKGVLFTFLTILPKEIIMVPCIIALGVNGI KFSLNIVKDKSAKQMSKNSLKTNFFAYCFVTLFFSCFLLVGILVEAYISPVFMRMMIS " misc_feature 103486..104085 /locus_tag="ClothDRAFT_3102" /note="Integral membrane protein DUF95; Region: DUF95; cl00572" /db_xref="CDD:153864" gene 104454..105338 /locus_tag="ClothDRAFT_3103" CDS 104454..105338 /locus_tag="ClothDRAFT_3103" /inference="protein motif:TFAM:TIGR02225" /note="TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: dol:Dole_1674 tyrosine recombinase XerD" /codon_start=1 /transl_table=11 /product="tyrosine recombinase XerD" /protein_id="ZP_05428984.1" /db_xref="GI:256003998" /db_xref="InterPro:IPR002104" /db_xref="InterPro:IPR004107" /db_xref="InterPro:IPR011932" /translation="MEELVLHFLDFLKNDKRLSLNTLQSYKRDIEQYITYLKDMKIQN IANTNKTTVIAYLLHLQKKGRATSTISRNLASIRSFYQYLTKKGIISQDPTENLESPK VEKKLPQILSTKEVELLLEQPKCDDLKGYRDKAMLELLYATGIRVSELISLDLDDVNL EMQYIRCNKGARERIVPIGSVSVNALQEYLTKSRNLLIQRPDEKALFVNVNGKRLTRQ GFWKIIKQYKNQAKINKDITPHTLRHSFAAHLLENGADLRSIQEMLGHSDISSTQIYA QLAKNRIKEIYKKTHPRA" misc_feature 104475..105335 /locus_tag="ClothDRAFT_3103" /note="tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225" /db_xref="CDD:162772" misc_feature 104475..105314 /locus_tag="ClothDRAFT_3103" /note="N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination of chromosomal replication, and stable plasmid...; Region: INT_XerDC; cd00798" /db_xref="CDD:29499" misc_feature order(104889..104891,104958..104960,105171..105173, 105180..105182,105249..105251,105276..105278) /locus_tag="ClothDRAFT_3103" /note="Int/Topo IB signature motif; other site" /db_xref="CDD:29499" misc_feature order(104889..104891,105171..105173,105180..105185, 105276..105278) /locus_tag="ClothDRAFT_3103" /note="active site" /db_xref="CDD:29499" gene 105491..106657 /locus_tag="ClothDRAFT_3104" CDS 105491..106657 /locus_tag="ClothDRAFT_3104" /EC_number="5.4.2.7" /inference="protein motif:TFAM:TIGR01696" /note="KEGG: ank:AnaeK_0954 phosphopentomutase; TIGRFAM: phosphopentomutase; PFAM: Phosphopentomutase domain protein; metalloenzyme domain protein" /codon_start=1 /transl_table=11 /product="phosphopentomutase" /protein_id="ZP_05428985.1" /db_xref="GI:256003999" /db_xref="InterPro:IPR006124" /db_xref="InterPro:IPR010045" /db_xref="InterPro:IPR013553" /translation="MKRAIIIVLDSVGMGELPDAAKYGDEGSNTLGNIAKNLPDFSLP NLESLGLGNIDGMTGYEPSKNPLGSYGRMAEKSAGKDTTTGHWEIAGLILDKPFPVYP NGFPEDIIKRFEDSIGTKTLGNVPASGTEIIKLLGDEHVKTGYPIVYTSADSVFQIAA HENVIPVERLYDMCRTARNILTGEHAVGRVIARPFIGESGNYKRTDRRKDFSLAPVGK TLLDYAVENGYKVKAVGKIEDIFGGRGITESVHIHDNMDGVDRTLEYMRDDFEGILFT NLVDFDMLYGHRNDIAGYANALKEFDRRIPEILANLREDDLLVITADHGCDPSTESTD HSREYVPLLVYGKKFKSNVNLGTRSTFADVAKTVAHYLGISSNLEGESFLGSIL" misc_feature 105491..106654 /locus_tag="ClothDRAFT_3104" /note="Sulfatase; Region: Sulfatase; cl10460" /db_xref="CDD:186998" misc_feature 105494..106639 /locus_tag="ClothDRAFT_3104" /note="Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676" /db_xref="CDD:145035" gene 106689..107990 /locus_tag="ClothDRAFT_3105" CDS 106689..107990 /locus_tag="ClothDRAFT_3105" /EC_number="2.4.2.2" /inference="protein motif:TFAM:TIGR02644" /note="KEGG: afw:Anae109_0662 pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like" /codon_start=1 /transl_table=11 /product="pyrimidine-nucleoside phosphorylase" /protein_id="ZP_05428986.1" /db_xref="GI:256004000" /db_xref="InterPro:IPR000053" /db_xref="InterPro:IPR000312" /db_xref="InterPro:IPR013102" /db_xref="InterPro:IPR017459" /db_xref="InterPro:IPR017872" /translation="MRMVDLINKKKRGEALSAAEIDYIVQGYTKGEIPDYQMSAFLMA VYFKGMNREETANLTLSMVNSGETVDLSMIEGIKVDKHSSGGVGDKISLVIVPLCACV GIPVAKMSGRGLGHTGGTIDKLESIEGFRTELTKEEFVNNVNKYKMAIVGQSPNLTPA DKKIYALRDVTGTVDSIPLIASSIMSKKIASGCDCIVLDVKVGSGAFMKSVDEAVILA KTMVEIGKALGRRTVAVVTDMSQPLGYEVGNANEVKEAIEILKGHGAEDETTVALTIA SHMAVLGGAFSDYESAYNHMRKLIESGKAVEKLKELIRIQGGNTDVVDNPNLLPQAEK HIEVKSSTAGYINSVNAEDIGVSAMLLGAGRKTKNDSIDFSAGITMVKKIGDWVDEGD TLCILHTNKSDFQEAERLSKNAFVIKNTKPEPIKYVHCVID" misc_feature 106692..106889 /locus_tag="ClothDRAFT_3105" /note="Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885" /db_xref="CDD:145834" misc_feature 106695..107909 /locus_tag="ClothDRAFT_3105" /note="pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644" /db_xref="CDD:162960" misc_feature 106911..107663 /locus_tag="ClothDRAFT_3105" /note="Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591" /db_xref="CDD:144256" misc_feature 107721..107942 /locus_tag="ClothDRAFT_3105" /note="Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831" /db_xref="CDD:116444" gene 108082..109296 /locus_tag="ClothDRAFT_3106" CDS 108082..109296 /locus_tag="ClothDRAFT_3106" /EC_number="3.4.16.4" /inference="protein motif:PRIAM:3.4.16.4" /note="PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; beta-lactamase; Penicillin-binding protein 5 domain protein; KEGG: pag:PLES_09771 D-ala-D-ala-carboxypeptidase" /codon_start=1 /transl_table=11 /product="Serine-type D-Ala-D-Ala carboxypeptidase" /protein_id="ZP_05428987.1" /db_xref="GI:256004001" /db_xref="InterPro:IPR001466" /db_xref="InterPro:IPR001967" /db_xref="InterPro:IPR012907" /translation="MLRKVIICFTAAVFLLNIMAISVLSAPAVGEPVYDVETVADIMA NTNVFELQAKSYVLMDAETGQILLENRSHERLPIASITKIMSMLLVMEAIDSGKINMD DIVTASEYAASMGGSQAYIEPGEQYTVRDALKAVATHSSNDVTVSLAELVAGSEQVFV VLMNEKAKELGMNNTNFLDCTGLTDEGHYSTAYDVALMSRELIVKHPKILEFTSIWMD TFRNGEFQLVNTNKLVHFYEGCDGLKTGFTRAAGHCLSATAKRNDMRLISVVLGEPDS NTRFAETRKLLDYGFANYESKQVNKKGEVVNEIEVKRALIPKIKALYGDDVKLLFARS DKGKVVREVRLKSSLTAPVAKGEKVGEVVYKIGEKEIAKVDLVSDRDVEKASFGKLFI NMLSSWFSLGRS" misc_feature 108082..109281 /locus_tag="ClothDRAFT_3106" /note="D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686" /db_xref="CDD:31872" sig_peptide 108082..108174 /locus_tag="ClothDRAFT_3106" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.579 at residue 31" misc_feature 108229..108939 /locus_tag="ClothDRAFT_3106" /note="Beta-lactamase; Region: Beta-lactamase; cl01009" /db_xref="CDD:186300" misc_feature 108961..109233 /locus_tag="ClothDRAFT_3106" /note="Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943" /db_xref="CDD:149169" gene 109510..110016 /locus_tag="ClothDRAFT_3107" CDS 109510..110016 /locus_tag="ClothDRAFT_3107" /inference="protein motif:PFAM:PF01810" /note="PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sat:SYN_02198 lysine efflux protein" /codon_start=1 /transl_table=11 /product="Lysine exporter protein (LYSE/YGGA)" /protein_id="ZP_05428988.1" /db_xref="GI:256004002" /db_xref="InterPro:IPR001123" /translation="MALWGIFISAFIIGFSGAIMPGPMLGVTIDGSLKKSWMAGPLIV LGHGILELLLIAVMTFGLKDFFSNLTVAGFIGLFGGLFLAWMGYGMIKSAVGKSVSLN GQRTGNNSYLRNLVFTGIYVSATNPYFIIWWASTGMESIRRAYEIGLLGVLFFMSDIF YRILHGTL" misc_feature 109570..>109974 /locus_tag="ClothDRAFT_3107" /note="LysE type translocator; Region: LysE; cl00565" /db_xref="CDD:186083" gene 110380..111873 /locus_tag="ClothDRAFT_3108" CDS 110380..111873 /locus_tag="ClothDRAFT_3108" /EC_number="1.1.1.205" /inference="protein motif:PRIAM:1.1.1.205" /note="PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; KEGG: scl:sce0088 inositol-5-monophosphate dehydrogenase" /codon_start=1 /transl_table=11 /product="IMP dehydrogenase" /protein_id="ZP_05428989.1" /db_xref="GI:256004003" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR001093" /db_xref="InterPro:IPR015875" /translation="MAYIYEEVSRTFSEYLLIPNLTTEKCTPDNIDLSTPLVKFKKDE ECSLKLNIPIVSAIMQSVSNDTLAIALARCGGLSFIYASQPIESQAEMVKRVKKYKSG FVVSDSNLTIDSTLKDVIELKNRTGHSTIAITDDGTASGKLLGLVTTRDYRISRNPLD KKVKDFMTPFSKLVVGKLGISLSEANDIIWENKLNCLPIVDDEQRLHYLVFRKDYDDH KQNPYELLDSNKRLRVGAGINTRDYKERVPALVDAGVDVLCIDSSDGFSVWQKYTLDY IKSNYNIKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATAVI EVAKARDEYFEKTGVYIPICSDGGIVHDYHIVLALAMGADFVMMGRYFARFDESPTKK VKSGNGYVKEYWGEGSNRARNWQRYDHGGESTNLKFEEGVDSYVPYAGKLRDNLEITL SKIKATMSSCGAASISELQKTARLTVVSSTSIIEGGAHDVILKDKDY" misc_feature 110380..111870 /locus_tag="ClothDRAFT_3108" /note="inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107" /db_xref="CDD:180842" misc_feature 110404..>110673 /locus_tag="ClothDRAFT_3108" /note="TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108" /db_xref="CDD:186823" misc_feature 110689..111033 /locus_tag="ClothDRAFT_3108" /note="This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key...; Region: CBS_pair_IMPDH_2; cd04602" /db_xref="CDD:73102" misc_feature <111067..111810 /locus_tag="ClothDRAFT_3108" /note="IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the...; Region: IMPDH; cd00381" /db_xref="CDD:73364" misc_feature order(111322..111330,111445..111447,111451..111453, 111514..111519,111586..111588,111592..111600, 111667..111672) /locus_tag="ClothDRAFT_3108" /note="active site" /db_xref="CDD:73364" gene complement(112182..113159) /locus_tag="ClothDRAFT_3109" CDS complement(112182..113159) /locus_tag="ClothDRAFT_3109" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05428990.1" /db_xref="GI:256004004" /translation="MVKRLRIISLISLILGTTLIMSASYFELFFPPKNAFYLGIFGDI ILTAIRSVGVSLITSTFINLIKFWVESTETLVKYDFVNRLTKKEMKDLKAKIETELYF RDNDHDKDNFYNFFERELSSLLNECYYKSYRTRIECHIGENYITKTIRKKFEIVNPSK KECTIKIPFGAEMQKVRQVENNKLYQIKKFAVDSVDFTKEINERIDISDNCLENSDAY CIKVHTFWDVKVKKKCTIDMVIETIVPLNDVCFSNKITRPCKEYSVIFILNDPSYQLS WHSFGFMGNHKDRIIEEPMDNGIEIGFKDWILPGDGVVISITKCEKKHV" sig_peptide complement(113091..113159) /locus_tag="ClothDRAFT_3109" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.958) with cleavage site probability 0.789 at residue 23" gene 113406..114719 /locus_tag="ClothDRAFT_3110" CDS 113406..114719 /locus_tag="ClothDRAFT_3110" /inference="protein motif:TFAM:TIGR01048" /note="TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: net:Neut_0404 diaminopimelate decarboxylase" /codon_start=1 /transl_table=11 /product="diaminopimelate decarboxylase" /protein_id="ZP_05428991.1" /db_xref="GI:256004005" /db_xref="InterPro:IPR000183" /db_xref="InterPro:IPR002986" /translation="MFVSKALKVNSKNHLEIGGCDCVDLVNNFGTPLYVMDESLIREN CRIYKNALDKYYNGNGLVLYASKAFCTMAMCKIVQQEGLGLDVVSGGELYTAIKAGFP MEKVYFHGNNKTIDELELAIDNNVRRIVVDNRQELLHVNRIAAEKGKTVNISFRIKPG IDAHTHDFIRTGQIDSKFGVALENGEAMEIIGEAVKLSNVKVVGLHCHIGSQIFELAP FEEAARVMLTFIAKIKEELGIEIEELNLGGGFGIKYTQDDDPIEYDRYIKSVSEVVKS VCEDKGIKLPFIVIEPGRSIVASAGITLYRIGTIKDIKGVRKYIAVDGGMTDNPRYAL YQSKYEGVIANKADAAKTEKVTIAGKCCESGDLLGKDVLLPEAEEGDILAILATGAYN YSMSSNYNRIPRPAVVLVKDGKARVIVKREDYNDIIRNDIIPEDL" misc_feature 113430..114701 /locus_tag="ClothDRAFT_3110" /note="diaminopimelate decarboxylase; Region: lysA; TIGR01048" /db_xref="CDD:162174" misc_feature 113490..114635 /locus_tag="ClothDRAFT_3110" /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828" /db_xref="CDD:143501" misc_feature order(113598..113600,113604..113606,113661..113663, 113730..113732,113871..113873,114021..114023, 114027..114029,114036..114038,114147..114152, 114276..114287,114396..114398,114408..114410, 114489..114491,114576..114578,114588..114590, 114600..114602) /locus_tag="ClothDRAFT_3110" /note="active site" /db_xref="CDD:143501" misc_feature order(113598..113600,113604..113606,113661..113663, 113730..113732,113871..113873,114021..114023, 114027..114029,114036..114038,114147..114152, 114276..114287,114489..114491,114576..114578) /locus_tag="ClothDRAFT_3110" /note="pyridoxal 5'-phosphate (PLP) binding site; other site" /db_xref="CDD:143501" misc_feature order(113604..113606,114027..114029,114036..114038, 114285..114287,114396..114398,114408..114410, 114489..114494,114576..114578,114588..114590, 114600..114602) /locus_tag="ClothDRAFT_3110" /note="substrate binding site; other site" /db_xref="CDD:143501" misc_feature order(113604..113606,114489..114491) /locus_tag="ClothDRAFT_3110" /note="catalytic residues; other site" /db_xref="CDD:143501" misc_feature order(113619..113624,113667..113672,113676..113681, 113736..113744,113754..113756,113799..113801, 113808..113810,113931..113942,114330..114332, 114336..114338,114360..114362,114366..114368, 114480..114497,114501..114503,114585..114593, 114597..114608,114615..114617) /locus_tag="ClothDRAFT_3110" /note="dimer interface; other site" /db_xref="CDD:143501" gene 114919..>117529 /locus_tag="ClothDRAFT_3111" CDS 114919..>117529 /locus_tag="ClothDRAFT_3111" /inference="protein motif:PFAM:PF00571" /note="PFAM: CBS domain containing protein; Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; KEGG: gsu:GSU1581 polyA polymerase family protein" /codon_start=1 /transl_table=11 /product="CBS domain containing protein" /protein_id="ZP_05428992.1" /db_xref="GI:256004006" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR001667" /db_xref="InterPro:IPR002646" /db_xref="InterPro:IPR003156" /translation="MKMEIITGHVNSDFDCLASMIAANKLYPHAVMVIPGIIGKDVRK FLNLYRDSFNFLSVKDIDIEQVDKIIVVDTNSKSRLEKPLGKLFEKPGVDIVVYDHHP PSENMIEARKAVIEDIGSCTALLVDEIQKLDIDITPLEATVMALGIYADTNCLTLPKT SSKDAYALAFLLSRRANLQVIDDYMTNPLNLNQQALLEKMGRNIRVVDINGFKVAFSA VEVEDYVDNAAFLTRKLLEERDYDAFFSVLRMDNKTYIIGRSLEDEIDVGHIMTFFNG GGHPGAGSGKSDEADLAKVVDLLEKTLKKNIRPVERAKDIMSSPVKTISLDSTIDEAN KIMLRYGHSGLPVVKDGILCGIISRRDVEKARIHGFGNSPVKAYMTKNVITIDPETPL KTIENLLVEHNIGRLPVVAGNKLLGIVTRSDVISTLFGENSPRWYKKNYIDSQDSALR NHNLADKINALPERVKNILIEAGKIADDVGLNAYVVGGFVRDLILGVENFDIDIVVEG DALMFSEKLAQHYQAHLTKHDRFGTAVVVLEDDFKIDVVTARKEYYEYPASLPVVEGG TIKDDLFRRDFTINSMAIKLNKSGFGNIVDFYGGRRDLQMGLIRILYNLSFVEDPTRI FRAIRFEQRYDFKMEEKTEEFAIKAIESGILGKVSHERINFEFFAMLKENNIWAILKR MEDLRILKNVYPEVVLSEDLKKLLKNAEENLACLKEKVSVQESLDRTLLYLLILYSNM SFEKAVKLSEKMRLSKEYKSEILKFIEAKDIILSNLSGNIDISNYDVYNELKELSMEI LFVLCMLSNEKKFIDRVILYINNLKNIKTCVTGKDLKELGVKPGPEYAVLLDKVLAEK LNGNLQTYNDELEF" misc_feature <114931..115833 /locus_tag="ClothDRAFT_3111" /note="Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887" /db_xref="CDD:33676" misc_feature 114931..115365 /locus_tag="ClothDRAFT_3111" /note="DHH family; Region: DHH; pfam01368" /db_xref="CDD:144819" misc_feature 115858..116193 /locus_tag="ClothDRAFT_3111" /note="FOG: CBS domain [General function prediction only]; Region: COG0517" /db_xref="CDD:30863" misc_feature 115870..116199 /locus_tag="ClothDRAFT_3111" /note="This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with an upstream DHH domain which performs a phosphoesterase function and a downstream polyA polymerase domain. CBS is a small domain originally...; Region: CBS_pair_DHH_polyA_Pol_assoc; cd04595" /db_xref="CDD:73095" misc_feature 116302..117528 /locus_tag="ClothDRAFT_3111" /note="tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617" /db_xref="CDD:30962" misc_feature 116302..116733 /locus_tag="ClothDRAFT_3111" /note="Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398" /db_xref="CDD:143388" misc_feature order(116377..116382,116389..116394,116419..116421, 116425..116427,116509..116511,116551..116553, 116566..116568,116638..116649,116656..116658) /locus_tag="ClothDRAFT_3111" /note="active site" /db_xref="CDD:143388" misc_feature order(116377..116382,116389..116391,116419..116421, 116425..116427,116638..116646,116656..116658) /locus_tag="ClothDRAFT_3111" /note="NTP binding site; other site" /db_xref="CDD:143388" misc_feature order(116419..116421,116425..116427,116551..116553) /locus_tag="ClothDRAFT_3111" /note="metal binding triad; metal-binding site" /db_xref="CDD:143388" ORIGIN 1 ttgggattat tgctgtatta tctgttttta tttttactct tattataggt tttacgaacc 61 aaacggcgtt agcttcaaac tcggtgcatc gcgaactcaa aatatatgtc gatgataaag 121 aattgcaatt tacagatgca aaaccttaca taagtgaatt tggaagaact atgattccaa 181 ttcgcgcagt tacagagagt ttcggagcaa atgttgactg gaacggtatt ctgaaaaagg 241 ttacaattac ttatgatgat atagaaatat attttcttgt tgttcatcct gataatattg 301 tagtaatcaa tgatttaaaa acgaatcaaa gcaaatctgt tccaatggac tccaagcctg 361 ttataaaaaa cgacagaacg tttgtgcctt tgcgagttat tggtgaagca tttggttata 421 aagttcactg ggatgcgagc gaatacaaag ttattattga tacaaagaat aaacagcctg 481 tattttttat aaatcctgct ttaagcgata cttattatca atgtgttgct aatttgaata 541 cagattttga aaatcttata ccgcaattga aaagagccag cggtagagtt aagcttactg 601 atgaagagag agaagattac ttgtccacag caaaatcaca tgttgagaat gttatcggaa 661 atgtggatta tagcaaagaa tttgctccat actatccgga tgctccattt acaggaatta 721 tgaaatctgt atatgatgat gctgtaaaaa aattcaataa taagggaagt gaagtttatt 781 gcggatcctt ctggcgttga tgttcttgaa gaggtagagg tttttgcatt aggacctaca 841 gaagtaatag ttgtcggcag actggaattt atatatcatg aagcatccga tgaatatctt 901 gaaaagtttg aaggtaagct taaaaaaggt gtttggtacg gtacgaatat agcagttata 961 tttactttat acagaccagc tggcagtatg gaagttgata aaattatttt agacaataca 1021 tttgaagaga taccgtcaaa taaagagtaa acacgagaaa agcggtataa caaattgaca 1081 cggttaagtc atggtgaatg acagaggagg actattgccc gggtaattag caattgtcct 1141 cctaattttt taattggaaa ggagaaatat gatgagcatc aaatgggaac aagaatggga 1201 taggatttat aaagaacaag gagaagtcca atctgaaata cttcctactg taaaagtgga 1261 aaaagatatt tttaagagat ttggatgcaa aaaagtaatg gacttgggat gtggtaccgg 1321 gcggcataca atatatcttg cccaaaacgg atatcaggtt tttgctgtgg atatttcaga 1381 gaccggaata gaagtaaccc gggcaaaagc ggaaaaactt aaccttacaa atattgagtt 1441 tgcacaactt gacatgagaa atctgtctgt tgacgataac ttgatggatg caattatgtg 1501 tgtatggaca agtggacacg gcacttttga agatgcgcgt aaaaatttaa aagagatgta 1561 tagaattctt aggctgggcg aaattttggt tattgattat gtttcgagag aagatgagaa 1621 ctatggcaaa gggacggaaa ttgagaagaa tacattcatc aataacgttg aaggtgaaga 1681 aaacattcct catcattatt ttgccaaaga agagattgaa gaattgtata cggacttctc 1741 agatgtcgat ataaatcctg tagactatta ttttactgat agttatggaa ccaggcacac 1801 cataaaggca tttgttgtta tagcagtaaa ataagccgag ttaacggttt agcaacccgt 1861 ttccatcgat gcttgcttgg aataattcag ccggattagt ttccgacggg ccgattttat 1921 cataatttta tgttaatttt atttcaatta taaggaatct tgtggtaata ttttatatag 1981 tatggactgt taatcgaagt atgcacatta aatatggtat gttgcattaa ggtcagttca 2041 acatatcaga ttttccggaa cgggatgttt tatggaaagt tcaatttgcc ttaaaaaagg 2101 gaggaatcaa aatgcaaaag aattttctat ttagaaggac aggggttatt gtcacgttgt 2161 ttgctcttat cttgggtttt gcatgcaaca tatcgtttgc ttcaacacca atgcagcgcg 2221 aacttaaggt atatgtcgat gacagagaag tgaaatttcc ggatgcaaag ccttacataa 2281 gtgaagctgg aagaacaatg gttccgattc gtgcagttgc agagagcttt ggagcaaagg 2341 ttgattggga tgccgtcttg agaaaggtta caattactta tgatgacata gaaatagaat 2401 ttttgccgga ttatgtcgag gatgtaatgc ttgttagaag tatagaaaag aaccaaagaa 2461 aaaccgttca attagactct aaacctgtta tcagaaacga tcggacatat ttgccttatc 2521 gtgctatcag tgaagcgttt ggctataaag tttactggga tgaaaaagaa tataaggtta 2581 ttgtagatac taaagacagg caacccgtat tttatataaa ccccggctta agtgataacg 2641 attatgagtg tatcgcaaat tacaatacag attttgataa tcttgcacaa gttttaaaac 2701 gcactgatgt tgaaattcaa cttactgatg aaatgagaga aagctattta tatcgggcaa 2761 aaaattatat tgaaaatata attggaaatg ttgattacag taaagaattc gagccggaat 2821 ttcccaccgc tccgtttaca ccggttatgg aagaagtata taatgatgct gtcaaaaact 2881 ctataatacg ggaagtaaaa ttcattgcag acccttccga tattgaagtt cttatgatac 2941 atccgatcga aaacagaccg tataaggtaa tggttttggg cagattggaa ttcatatatc 3001 atgaagcgtc cgatgaatat cttgaaaagt ttggaggcaa gttgaaaaag ggtgtccggt 3061 acagtacaaa aatagctgta acatttgagt tgaaaccgaa tgatgcgggt cttggacatg 3121 ctattttaga caatacattt gaagaaatag aataaaaggg acgagcctaa aattataaag 3181 tctgaaggca atgacgaaaa attggtcttt ctgccttcag actttaaatt ttctaactgt 3241 caaaaataac tgccaggatg cccataaaag tgagaattaa ggattgacga ttaagcgttt 3301 tctcatgttt tcatagatac atttgtacat tttgaaagtt ttctcggaat tttcatcgtc 3361 gcaattaata tcaggatgat atttttgaat gataccgttc cagccgattt ttaagatttc 3421 ttcctggatt tcgttgaatt tgtttattag ctgcttgttg cgctgaattg attccataaa 3481 atactccccc cgaaaaaaat actttatatg aatctaattg catagatcaa ccatgtatta 3541 acaacgatta ttggtattat gttttctata tttataagta aattatacca tcagaaaagt 3601 tttatatcaa tatgttcgca gcgaaatagg actgtatgat tattcctgaa ttatgtaaat 3661 aaagcttaag ataacagtga atgaatatag tttcattatc ttaagcttta ttttaatatt 3721 ttcatttttt ctttttcgat tttgctttta taccttcaag ctttttatct gcagaacgta 3781 gaaggagaaa gaatgaaaca ccaagaatcg caacaacggc tagcaaataa acccaagttt 3841 gccatggcat atttttttat cacctccacc aataataatg aattttatca taaaatatgt 3901 acaaaatcaa ttgaaaaaag gcagaagaat tgacaacaga aaattctatg taaagatgtc 3961 atttaagttt aataaatgtt tcattattat gaaagaataa aactgtatta cataatttat 4021 tatatcagaa aagatgatat gaggaaatga catgaagacg acattaatac ttggtgcagg 4081 tttttcaaaa aattccggat tgcccataca atctgaaata cctgcgttgc tgacaaagta 4141 caaagaaaat agcaattttg agcgcagtgt ttcccttgta ctggaaagct ttatgaggga 4201 tgtttttggt tttgaaaaag acatataccc ccagcttgac gatttgctta cttgcataga 4261 tatatccacc aattcagaac atcatctggg gataaactat tctcctgttc accttaaagc 4321 tttaaagagg ctgataattt acaggatttt tacaattttg gaagacagct ttacatattc 4381 caaagaggta gaaaagctga taaggttttt tattgaaaat aggcttgagt atacgggttt 4441 tttggtacta aactgggata cggtgcttga aaaatatatt tctgcaattg ctccaaaggc 4501 cataatagat tattgcaatg gtggcaggta ccttacggaa gaccttcgtt ttgaagaaaa 4561 aagggatgga aaaagaaaag ttgaaattct gaaagtccac gggtcgtgca attggcttta 4621 ttgtgacaac tgtagaatat tgataaatga tactgtgtcc cgggtgccta atataaggaa 4681 ggttgggttt aaaaaatctg attttaagct gtttgatgaa atgaaaaaag taacggacaa 4741 agtttttttt gaggatgtcc gatgctttat atgcggagat attgtttctg ctcatatagc 4801 aactcaaagt tacaggaaat cttttaggac aaattccttt cccagcatat gggacaaggc 4861 cgaggatatg ctgacaaatt ctgaaaagtg ggtttttatc gggtattcac ttcctcaggc 4921 ggactatgaa ttcaagcacc ttttaaaaat ttgcgagcat aaacttgggc acaaaaaaga 4981 cagaagactt tctattgatg tggtgctttt tgacagtgaa actacagcca tgaggtataa 5041 aagttttttc ggaaataaaa tcaacaggat ttttaacagt gggattggtg agtatataag 5101 ttatcttgaa agcacttaaa tattttccgg ataaatgtta taataccgtt tgggctacga 5161 tttccgatgt agaagttaaa tttagggagt gatgaagttg aaactgaatc tgaatttaaa 5221 caatgcgaga tttgagatta cggctgtaag accggaacag tatccgaaaa atgatttacc 5281 ggagattaca tttgtgggaa gatccaatgt gggaaaatca tcactcataa atacaatgct 5341 gaacagaaaa aatcttgcaa aagttgctgc aacaccgggg agaaccaggg ttataaattt 5401 ttacaacata gatgacaaac tttattttgt cgatcttccg ggctatggct ttgcaaaggt 5461 gccaaaaact atgaagaccg gctggaaaga tataattgaa acttatctta tagaaagaaa 5521 acagctgaag aaagtaatca tgctggtgga tatcaggcat tcgccgactt ctgacgacgt 5581 gcttatgcat gaatggctga aagctatgag aaaatcctat gtggttgtag ctaccaaact 5641 tgacaaaata ccacgcacaa aaataaaaga gaggatttcg gatatacgca gcatcctgaa 5701 gcttgaggat gatgtaaaaa taattccctt ttcttcagaa acaagacagg gaagagatga 5761 gttgtgggat gaaattttgg atgaatcata ttttgttgaa tcatattttt catgaaatgg 5821 acaattttga ctttacaact taattgccgt tgatatataa tgaataaaaa aatagttcat 5881 cacgctaggg gtgccattgt ggctgagaaa gagacttaag tctcttaacc ctttgaacct 5941 gatgcggtta gtaccgccgg aggaaagcgg aaaatattgt tttttagctt attgacgctt 6001 atccttcggg ataagcgttt tttagttcta tgaaatttca ttggttgcgt gaaattttat 6061 ttagcaggga ggtgacagga tgtttataac gttaaacggc aagcagactg aagtggataa 6121 cgggacgaca cttgtgggtt tgatccaaag caaaggtctt gagccggaaa gcatagttgt 6181 tgagtacaac tatgaggttc ttccgaggga aaagtgggac agtgttgttt tgaaagaaaa 6241 cgataatctt gaagtactgc gatttgtagg gggtggataa aaatggatga taaattgatt 6301 attgggggca gggaaattat cagcaggctt ttcatcggta ccggtaaatt tcccgcaaac 6361 aggataatac ctgatgttgt aaggatgtca ggagctcagg ttgtcactgt ggcattaaga 6421 aggattgact ttgattctga tgaggagaac atgctaagat acattcccaa agactgtatt 6481 cttatgccaa atacatccgg agcaagaaat gccgaagagg ctgtaagaat tgcacggctt 6541 gccagagctt ccgggtgcgg caattttatc aaaattgagg tgatatcgga caataggtat 6601 cttcttccgg acaacctgga aaccataaaa gcaacggaga tattggtaaa agaaggattt 6661 atagtgcttc cgtacatgaa tccggacctt atggatgcca gaaggcttaa ggatgccgga 6721 gcggctgccg tgatgccgtt gggagcaccg atagggacca ataaaggact taaaaccagg 6781 gaaatgatta aaattctgat tgatgaaatt gatattcctg tgatagtgga tgccggtata 6841 ggcaagcctt ctgatgcctg tgaagctatg gaactggggg ctgatgctgt tttggttaat 6901 accgcaattg ccactgcggg agatccggtg gttatggccg aagcttttgc aaatgcggtg 6961 atagccggaa ggaaggcata tctttccggt ttgggtccgg taaaagaata tgcggaagct 7021 tcatcgcctc ttacgggttt tttaagatga caggataaaa aagctgtttg acggattaaa 7081 ggaagttatt tgccggatag gaaatcttgc ttaaattatt cgtttaataa attatgttaa 7141 ataaaaaaat tatttgcacg gtgaatgggg aatgaacaat gagcttttat gaaagatatc 7201 tggagtacaa aaattttgat tttgaaaatt tcttcgacca agtaacggac agggatatta 7261 ttaatataat aaacaaagac cggcggcttt cggaactgga attcctcatg cttctttcaa 7321 aaaaagctgt aaaatacctt gaacccttgg ctcaaaaggc aaacaggatt acggtgcaga 7381 atttcggaaa ggtcatattc ctgtacacgc cgatgtacct tgcaaattac tgcgtaaatc 7441 aatgtattta ctgtggtttt aacataacca acaatataaa gcgaagaaaa cttactttgg 7501 atgaggttga aaaagaagct tatgcaattt catccacggg tcttaggcat attctgattt 7561 taacgggaga gtcccgaaag gaaagtcctg ttcaatacat aaaggactgc gttaaaattc 7621 ttcaaaagta tttcaggtcc atatcaatag aggtttaccc tcttgaggag aacgagtacg 7681 ccgaactgat agaggcgggg gttgacggtc ttaccatcta tcaggaggta tatgatgaag 7741 aaaaatacaa ggctcttcac ctgaaaggtc ccaaaagaaa ctacttatac aggcttgatg 7801 ctcctgaaag ggcatgcaag gcatcaatga ggaatgtaaa cataggtgcc ctgctgggac 7861 ttcatgactg gcggacggag gctttttaca cgggacttca cgctgattac ctgcaaaaca 7921 agtatccgga tgtggaaatt ggtttgtccc ttccaagaat aaggccccat ccctgtggaa 7981 gttttgtacc tgattgcaaa gtggaagaca gggatctggt acagataatg atagcctaca 8041 gattgtttat gccaagagcc gggatagcaa tttctacaag agaaagagag agccttagaa 8101 ataatcttat tggtctggga gttaccaaaa tgtctgccgc gtcaagtaca gaggtcggag 8161 gtcacaccct tggcgataaa agtgacggac agtttgatgt aaatgacagg cgcggtgttg 8221 aagagatgag acaaatgata tacagcaaag gttatcagcc ggtgtttaaa gactggcagg 8281 caatataaaa aacagcaata tggaaacgca atatagaaaa agctttatgg aataacaggt 8341 ggtacagaaa tttgggaggc ggctatgaat gaatttgaaa ttgggcttat gtcttatcta 8401 ggcagggaaa agcttgaaaa gctcggtaaa gtaaaggtgg gaatcgccgg ggccggaggg 8461 cttggttcca attgtgcatt gcacctggtg agaagcggtt ttaaaaattt aaaaatagtg 8521 gattttgacg tggtggaacc atctaatctg aacaggcagt ttttcttcct ggatcagttg 8581 ggacgtccca aggttttggc tctaaaggag aatttggcaa gaatcaaccc tgatgtaatg 8641 atagaggcta tacagcaaaa agtagacaga aataatgcaa agcagctgtt tgatgactgt 8701 gacgctgtgg tggaggcttt tgataaagtt gagtgcaaaa ccatgatggc ggaggctttt 8761 gcctcgtcgg gaaaattttt tgtatgtgca tcgggacttg ccggttgggg aaacagtgat 8821 gaaataagaa tacgaaaagt acatgacagg ttctatatag tcggggattt tgttaccgga 8881 gtcaaagaag gcatacctcc catttctccc agggttaata ttgcagcagc aaaacaggcg 8941 gacttgattt taagcttctt tttggatgat gcggataata ccgtaaatgt gaattgtcag 9001 gaaggatgat gggattggac aatctttaca gagtgctgga tgccaatgtc aacaggacat 9061 cggaagggct tagggttttg gaggatttgg caagattctg ttataatgac agactgcttt 9121 caaagaggat taaggaacta agacacagtg taagaaagaa tattgcagga ttggttccaa 9181 accttataag cagcagggat tcggtgaatg atgtgggttt aaaaaacgtc aatggagatg 9241 gatattgacc gaaaagcctc acttttggat cttgcccggg caaatttcaa gcgggttcag 9301 gaagctttga ggactgtgga ggaaagcctt aaagttttga atgaaaatga cctttccaag 9361 ttttatgaaa gttgcaggtt tgaaacgtac agcattgaga aggaatattt taaagttttg 9421 actttcgaaa ataagaaagg cagattgaat gaaataataa ccggtcttta ttgtattaca 9481 tcggaagaac actccaaagg gcgcagtaat attgaggttg tggagaaaat gataaaggcc 9541 ggggtaaaga taattcaata cagggaaaaa aagaagagtc ttttggaaaa atacaacgaa 9601 tgcaaaaaaa taagggaaat gaccttagat tcgggcgtta catttatcgt aaacgacaac 9661 attgatattg caatgatggt aaaggccgac ggagtacata taggtcagga tgatcttccc 9721 atagaaaaag taagagagct tgtgggggat gagatgatta tcgggatatc cacccattct 9781 ccaacgcagg cggaagatgc ggtaagacgc ggagctgatt atataggagt gggtcctctt 9841 tacagaacat atacaaagga ggatgtctgc gaacctgtag ggcttgagta ccttgactat 9901 gttgtgaaga acataaatat tccctatgtt gccataggtg gcataaagga acacaacatg 9961 gatgaggttt tggcccgggg agcccggtgt atagccatgg ttacagagat tgtgggcgcg 10021 gatgacatag aagaaaaaat ttccaaagta aaatcaaaat tttcgagagg ggttttataa 10081 aatgtataca actcagatgg atgcagccaa aaaaggaata ataaccgatg aaatgagaat 10141 agtggccgaa aaagagggtg tgcatgttga gaagttgcga gagcttgttg catcaggcaa 10201 agtggtcata ccggccaata aaaaccacaa aaaacttgag cctcaaggaa taggagaagg 10261 tttaagaaca aaaatcaatg ttaatatcgg aatatcgaag gactgctgca attttgagat 10321 ggagttggaa aaggcaaaaa aggcaattga gcttaaagcc gaggcgataa tggatttaag 10381 ttcctacgga aagacaaggg agtttaggcg aaagcttgtg gaaatgtctc ctgtaatgat 10441 aggtactgtg ccggtatatg acgcggtggg gttttatgaa aaagacctta aagatattag 10501 cgctgaagaa tttttcgaag tggtggaaaa gcatgccgaa gacggtgtgg actttatgac 10561 aattcatgcc ggcataaacc gggagaccgc aaagagattt aaggaaaacg gcagacttac 10621 caatatcgta tccagagggg gttctttgat atttgcatgg atggagctta cgggaaatga 10681 aaatcccttc tatgagcagt atgacaggct gcttcaaata tttgaaaagt atgatgtcac 10741 cataagtctt ggggatgcat taaggccggg aagcataaat gattccaccg atgcgtcgca 10801 aatacaggaa cttattgttt tgggagagct taccaaaaga gcatgggaga agaacgtaca 10861 ggttatgatt gaaggaccgg ggcatatggc cataaatgaa attgccccaa acatggtttt 10921 ggaaaaaaag ctttgtcacg gtgcaccttt ctatgtttta ggaccgattg tcacggacat 10981 tgcaccggga tacgaccaca taaccagtgc tattggagga gccattgcgg ctgcaaacgg 11041 tgcggatttt ctgtgttatg tcactcccgc ggagcatttg aggcttcctg acatagatga 11101 catgaaagaa ggaattatag cagccagaat tgcggcccat gccgcagata tagcgaaagg 11161 aatcaaagga gcaagggaat gggactacca aatgagcgag gcaaggagaa accttgactg 11221 gaacaggatg tttgagcttg caatagacag ggaaaaagcg gaaagatacc gcaaaagctc 11281 gatgcctgaa gatgaagaca cctgtaccat gtgcggcaga atgtgcgcag tcaaaaacac 11341 aaacaaagcc cttaagggtg aaaaaataaa tattctttaa agtgtatgga agtatactct 11401 taagggagga aaaatcaagg gggcaagggg gataacccct tgtttattaa tacctgggta 11461 tttagtgctt taaggtatct aattaatttt ttatatatat aatttaggag cttgcttaaa 11521 gtttgataca aaaaactgca gcttaaagaa tgccgcaggt aatgtatatt aatgtataga 11581 ggaaaaagta tgttaaaaag tttccaagta cgttattagt atattacaac tatatggttt 11641 aggtaattgg taaactgaac aataattaaa aaaataagtc tcgttttttg gtgaaaatac 11701 tacaaaaaca ataatgactt tttatgtatt ttatataaaa tttgttgtat aaatcgcaaa 11761 aaatatgatt ttaaaaggat ttttagcgga ttgcgaagaa atatataaaa taatgacttg 11821 atgttatttt gtgctaaatg agttgttgag gagttctgaa tgtatccttt gaatattgac 11881 ggtgaagagt tgtaccttag ggacttgaaa ataaatgatt tgccgaattt gttgaaatgg 11941 tacaacaata ttgatgattt ttcacttgca acgggtgttt acaagcccat aactctaaag 12001 gaaatactgg aaagatattt taaatgtcag tcttcatcta aagatttctt tgccggaata 12061 tacatacgta aatcaggtga aatgatcggc gttctgaaag gctggttaga ttgtgagaag 12121 gatttatccg catggattaa ttccataata atagacccgg gctttcagag gaaagggtac 12181 ggaagcaaga cggtaaatct gtttatccgg catgtaaagg aatgttgcaa tgtaaagaga 12241 gtgtatcttt cggtggcaga agaaaacttc aaaggaatga gtttttggaa gcagcagagt 12301 tttagagaag tgaaaaagat aagcaaagat agggattctg tgagtaaatg caagagcata 12361 gtgataatgt gcagagaaat ataaattaga tattgactca atgtccatat gttttttgcc 12421 gacgggttaa aatatcagcg aaaattgtcg ataaatatta caaaagatac tttttgtttc 12481 gatcgggcaa acaatccggt tgacaaattt gcgacccggc aatttgacaa atggaaatta 12541 gaaatatata atatttgtgg ttgtataaaa tttaccatgt gttttttgta tgaagtttat 12601 gtggagcgtt gtttaaagtc atttggtttt gcaaaaggaa taggaaagaa aaggaacgga 12661 ggataaagga tgttaaagtt taacaaggtt ttcatgtaca taactgcttc ggctttgtct 12721 gtttctttat ggacatgtac ttcttttgca cagcagaaca aaacgggagt aactactgca 12781 agcatgctta atatgcgtga aaatcccagc acttcgacga aaatcataga ccaaattcca 12841 aatggaacca aggttgatat aatagaaact tcaaacggtt ggtataaaat ttcgtacaat 12901 ggcaagacag gatgggttta cggttcttat gttaaagtaa cggagacacc aaaactgact 12961 gtgacggatg aaacgatatt ggcgactttg aataaaggtt ctaccggtaa ttcttcaacc 13021 aattcttcta caaataattc tgctgtcaac aattcttcca gtcaagtggt cgatgaaacc 13081 attcaaaaac ctgctcaaaa tgctgcatcc ggagaaaaca ctgaaaatac cgttgtaaaa 13141 acaggaattg tgaaagcttc ggctctgaat gtaaggcagg gaccgggtac ttcctatagt 13201 attattaatc agctttcaaa cggcgcaaag gtaaatataa taaaagaaga gtccggctgg 13261 tatcaaatca agctggcaaa cggttctaca ggttgggttt caggtacata tgtgaatgtc 13321 aatactacca ttgcttcaag aggaggactt tctgaaaatt cagctccggc agcttcaaat 13381 aacagcgatg tgtccgatgt gagacagcag gttgttgaat atgccaagaa atttttagga 13441 gtcaaatatg tatatggagg aaattcgcct tctcagggat ttgactgttc cggttttgta 13501 aaatatgtgt tcagcaattt tggtattaat cttgaaaggg ttgccgcaag tcaggcaaag 13561 cagggtacat gggtttccaa ggatcaattg ctgcccggcg acctcgtatt tttcgatacc 13621 gacggaggac ataattatat taaccattcc ggcatataca taggagatgg aaagtttatt 13681 catgcatcat cgggaagcgg caagaagagt gttgttataa gtgaccttac gagcgggttt 13741 tatgccaaca cttatatgac cgcgagaaga gttttaaatt aaatgaattt aactaaaaat 13801 ataatttaag gggaatttac gagaaaagct ccttactcga aggagctttt taaagtgcag 13861 aatgaaaaga ccgctggttt gttttagtct gtctcttatg gccggaattt tatgcaccaa 13921 tttaacccat tcatacttgt ttgctttttt gtcctgtgtg gtaattggtg ttattgcgtt 13981 tattctatta aagaacaagg ataacgccaa atttatagtt ggcggaattg ttctgtttta 14041 ctttattggt gcggtatatt acttatacgg ctacaaccgg aaccttcata aatttgaaga 14101 gtttgccggg aaaaatgttg taataagggg atatattgat tcggcgccgg aaattaaagg 14161 gtcaacaatc agatatgtac taaagacgga ggaaattcgg ctaaaagagg attcaaacca 14221 ggaaaagaag attcggggaa aaattttact ttccgtgcag aaaagcgatg aagttccgct 14281 ttttgaatat ggaagggaaa taaaaatatc gggtaaaata agtattccta aaggcagaac 14341 caatcccggg ggatttgatt acaggaagta tctcaaccac tccgggattt ccgccactgt 14401 ttttgttgtc ggcagaaata tatacccgca gaaaaacgta aaaggcaata tatttgtcaa 14461 agcaggccta agtataagag aaaggattgt aaatgtaata aaccagagcc ttccgcctca 14521 gcaggcggga ctacttagcg gcatgttgat aggctacagg gaaggacttt ccgaggaagt 14581 ggaagaagct ttcagcaatt ccgggctgac tcatttaatg gcggtctcag gagcaaacgt 14641 tgcttttatc atgcttcctc ttgtctttat atttaaaaaa cttaggttta ggcaaaacat 14701 ctacaacatt ataatcattg gtatcctctt gttgtttacc tttattacag gatttgaacc 14761 gtcagtcctg cgtgcggtaa taatggcgat agttatcctc gtggggcaga ttttaaaaag 14821 ggagacggat atttttacca gcattgcctt tgctgcaatt ctgcttcttt tattaaatcc 14881 cggaaacctt tttaacatag ggtttcaatt gtcctttgca gcaacaattt cactggtttt 14941 gttctatacc aatttaaaaa acatgttaaa tttcggcttt cttccggaat ttataaccga 15001 tgtgctggcg tctacactgg cggctcaaat aggagtattg ccgataacgg tgttttattt 15061 taataaaata tctcttatat cggttttgtc aaacctcata gttgcaccag tagtggaatt 15121 tattacaatt atggggtcct tgatggctgt tttgggacaa atacatataa tcttctccgt 15181 attgataggt tattgcaaca acgctctttt aagttttgtg ctctttgtca caaaaacgac 15241 ggcagagctg ccttattcgg ttataaccgt ttcaacgcct tctgttgttt tagtgataat 15301 ttattatatt tttatattgt ttttattttg gtacaagcct aaatacaagg taaaactaaa 15361 cttaaagtat tgcgtattgg caggggctgt atctgtagcg ttgatagcgg ttagcttcct 15421 ctggcctaaa ggaatggaag tggtgttttt ggacgttggg cagggggatg gtgcttttat 15481 cagaacatgc agcggcaaga ctattttgat tgacggtggt ccggaaagtg ctggagaaaa 15541 cgctgttgta ccgtttttat tggattatgg tgtgacagaa attgacctgg tggttgtaag 15601 ccatggacat gacgaccatt ataaagggct tttgcccgta cttgaaaact tcaaggtgag 15661 aactcttata attcccgacg ttgatactga tgaaggactg ctggatgcaa ttgaaattgc 15721 ccgaaaaaga aaaatttcgg tggaaaagtg tgaaaaggac gatgtaatta cccttgacaa 15781 aaaaacgtat attgaggttt tgcatccaag ggaagggatt tatttcaatg agtccggcat 15841 aaacaacagt tctttggtgt taaaactcaa tttcaaagat gtgagcatac tgtttacggg 15901 agatattgaa aaagaggccg aaaggctgct ttgtgaggat gaggtaaatc tcgatgcgga 15961 tgtgttgaaa gtggcgcacc atggctcttc tacatcttcc acggaggaat ttttggacag 16021 tgttactccc gatgtggctg ttataagcgt gggtaaaaac aatttcgggc atccttccga 16081 agaagttctt cagcgtatgg aatcaaaggg tatatatgtc ttaagaaccg atatatccgg 16141 ggccgtagta ctgaaaactt atggggaaaa gattaggata agaccaaccg taccgtaaat 16201 tgttttatgg gtgcctaaag gtatttaaag gattgttcaa ataagacaat gcattataaa 16261 atttaacagt ttaaataata aataaatcac ggtttatttg ttataattta tagagtatgg 16321 ttaaattaaa ttattatggt taaataaaat ttattcagaa ttattctaag acttggcggg 16381 gtgaatacat ggactatata aatatattaa aggatttaag tacatatccc ggggtatccg 16441 ggcaggaaga caagctttcc gggtacattg caaagctgtt tgaaaaatac tgtgacagtg 16501 tggaaataga tgaattctac aatgttatcg ggataaaaaa gggcataggc ggttccggag 16561 gcagaaggat tatggttaca gcccatcttg acgaaatagg tttgatggta aaaagtattg 16621 acgaaaaggg gtttatcact gtctcaaaca ttgggggtgt ggacagcaag gtccttctgg 16681 cccaggaagt tgtaattcat ggaaagaaag agatatatgg cattataggc gcaaagcctc 16741 cgcacctttt gactccggaa gagataaaaa aggcggttaa gatggaggac ttggttatag 16801 atacggggct ttctgcagaa gaagtgagaa aatatgtatc tgtgggagat attgtgactt 16861 ttaaggtcga gccgttagtc cttcagaaca acagatttag ttcaaagtct ctggacaacc 16921 gggcgggagt tgttgctttg ctggacataa tggaaaattt gactttgctc aatcacaaag 16981 atgatgtatg gtttgtggct acggttcagg aagaagtggg gcttagggga gccaatattg 17041 ccgcctataa tataagcccg gatttggcaa tagtgattga tgtctgccac ggccagatac 17101 ccggcacacc gaaggaatcg gtgtttcctg taggtaaagg tccggctgtc gccgtcggtc 17161 cgaatcttca tagaaaatac acaaaaaaga tgattgagct tgcaaaagag gaaaatatac 17221 cttaccagat agatgtggag cccggggaca ccggtaccga ggcttgggcc gtacaggttt 17281 caagagaggg aattccgaca cttttggttt caattcctct aaagtacatg catacggtaa 17341 tagaaacttt aagcatagat gatataaaaa ataccggaag actgattgca agatttattt 17401 caatgacagg aaacgaaatg gaggaaggac tgtgctgata aaagaattga cggagttaaa 17461 cggggtatcc ggaaatgagg atgaggtaag aaaatttata aaagaagagg cgcaaaagta 17521 tgcagacagc ataaccgagg actcaatggg aaatttgatt tgctataaaa aaggcggatc 17581 ctcaaaatac cgcgtaatgt tgtccgccca catggacgag gtcggattta tggtaacggg 17641 gtatgatgac ggtctgatca aatttgcaag tattggtgga atagatgaga gaatacttcc 17701 gggaaagagg gttttggtcg gggaaaagcg gattcccggt gttataggtt caaagcccat 17761 tcatctgcag gaaaaggctg aaaggggaaa taatatcaag ctgaaaaaca tgtatataga 17821 cataggtgcc gaaaaaaagg aagaagccga aaaacttgct cctttaggtg aatacatagc 17881 cttttacagc atgtatactg agtttggtga cggctgtata aaggcaaagg ctttggatga 17941 ccgtgtcggt tgtgccatac ttcttgaaat attgaaagag aggtatggat ttgatttgta 18001 tgtatgcttt accgttcagg aggagatagg cttaagaggc gcaggcgttg ctgcgttcag 18061 ggtaaatcct gatattgcaa ttgttgttga aggaaccacc tgctctgatg tgccgggagc 18121 ccgcgaacat gagtattcaa cggtaatggg aaatggagcg gcactaacta taatggacag 18181 aacttcctat tccaataaaa agctggttga ctttatgtac aagacggcga aagataaaaa 18241 cataccggtc cagtacaagc aaaccgcaac cggcggaaat gatgcaggaa agatacagtt 18301 aacccgtgag ggagttgtgg tggcatcggt atctgttccc tgcaggtata tacattcccc 18361 tgtgtcggta atgaaccgaa gagactatga aagttgcttg aatctcgtaa aagctgtgct 18421 ggaggagttt gacaacaatg agagcttaat tgaaagtttt aaattgcaca atgtgaagta 18481 aaatgaacta aaattacgta aatcacagaa aaatggagga agaggatatg tttgacttgc 18541 tcaaaaagtt tacaggaatc gttggagtat ccggaaacga agaagaaata agggaagcta 18601 taattgagga aattaaagaa tgtgttgacg aaataaaagt tgatactttg ggaaacctta 18661 ttgccgtcaa aaaaggcaag ggcaaaaaaa tcatggtggc ggctcatatg gatgagattg 18721 gcgtaatggt tacatatata gacgacaagg gctttttaag gttttctgcc gtcggagggg 18781 tcagccgcta tgactgtata ggccagaggg tgaagtttaa aaacggagtt gtcggagctg 18841 tttattacga ggaaaaactt gaggatatga agaatctcca gctttccaaa atgtatatag 18901 atattggagc aagaagcaga gaggaagccc tgaagatggt aaatatcgga gatgtcgcct 18961 gctttgtcgg agatgcggtg cttcaggggg ataccgtgat atcgaaggca ttggacaaca 19021 gaagcggctg tgcggtggtt gtaaaggcga taaaagagtt gaaaaagacg gataatgaaa 19081 tatattttgt gtttacggtt caggaagagg tcggtttgag aggagcaaaa accgcggctt 19141 tcagtataaa gcctgatata gccatagctg tggatgttac aatgacggga gacacaccgg 19201 aatcgcatcc tatggaggtt aagtgcggcg gcgggcctgc aattaaagta aaggatcgtt 19261 ccgtcatttg tcatccggag gtaagaaaac ttttggaaga gtcagcaaaa aggaataata 19321 ttccttatca gttggaaata cttgaagcag gagggagcga cccgggctca atacatttga 19381 cggcgggagg aataccttcg ggtgcgatat ccataccggt gaggtatgtt cacagtccgg 19441 tagagaccgc cagcatgtcg gatattaata atgccgtaaa attgttggtt gaagccattt 19501 gctgatattt atatgtatga gattaataga ttaataaaga gatttataaa aggcttcctg 19561 cctttatggc gggaggcttt tttaataaat cagatttttt gattatggga tattaaccta 19621 attggaacct gtgatataat actgagagtg tgaatttaca ttctgatttg caatataaat 19681 gttttggggt tgcaaaattt ttgagcatat gatgtgtgtg ttaaagtttg agaaaatgag 19741 taaaattggt ttaaggggtt tttatttatg agcaaatatt ggagtaatat agttaaaaaa 19801 ataagtccat atgttccggg agagcagcca aaggacaaaa agtacataaa actgaatacc 19861 aatgaaaatc cgtatccgcc ttcggaaaaa gttttaaagg caatttcagc ggcggtaaat 19921 gaaagcctga ggttataccc ggatccggct tgtgaaagct tgaggaatac tttggctaag 19981 tattacggga ttaaagcttc ggaagttttt gtgggtaacg gctcagatga acttttggct 20041 ttttcgttta tggcgttttt caatcccgga gacactatta tttttccgga tataacctat 20101 agcttttatg aggtttattc ctcgatgttt tccgtaaact acaggttgat tcccttggat 20161 gatgaattta acgtccctgt ggaagagttt ttcaccgaaa acgacggaat aatactggca 20221 aacccgaatg ccccgaccgg caaagctctt ccgcttgaaa gcataagaaa aatacttgaa 20281 aagaatgatg acaaagtcgt tattattgac gaagcatatg ttgatttcgg agcccggtca 20341 tctgtaccgt tgataaagga atttgaaaat cttttggtta ttcagacact gtcaaaatcc 20401 agggccctgg caggtcttcg tgtgggtttt gctttgggaa gcgaacagtt gatagagggt 20461 ttggatcgtg taaagaattc cataaactca tatactctgg acagacttgc ccttattggt 20521 gcggaagaag ccataaagga tcatgagtat ttttgtgaaa tcagagataa gataatcaac 20581 accagggagt gggtttcaaa gaagctgtct tccatgggtt ttaaagtgat tgagtcaaag 20641 gccaacttca tttttataag tcatccaaaa ataaacggca ggctgttgtt tgagaagtat 20701 aaagaaaaca atatcctggt tcggcatttt aacagcccga gaattgacaa tttccttcgt 20761 gtcagtatcg gttctgatga agaaatgaat atcttttgtg agaaaacaaa agaaattatt 20821 gaatcattaa attaatcttt tgaaaaataa gaaaatttgt aaaaattcat ttttttaaaa 20881 ggtaaaaatg ttcgtgtgta gaataattca agtatggaat aaataaaaaa tttgtgaggt 20941 gtaaaatgaa gataaccttt ttaggtgctg caaaaacggt taccggctca tgtttttttg 21001 tggagacggc gtctactaaa tttcttgtcg attgcggcat gtttcaggga tattccaaga 21061 acaatgcgtt aaatgaagag gaatttcctt ttaatgttga agaacttgat tatatttttc 21121 ttacccatgc gcatatagac cacagcggaa gaattccgag aatttatatc aaagggttca 21181 ggggacagat aattgccaca aaggctacgg tagaactttg tgccattatg cttcccgaca 21241 gcggtcatat tcaggagtat gaaaatgaat ggacgaacag aaaaagattg cgtgcgggaa 21301 agccgccggt tgagcctttg tatacatatc aggatgcggt gaattgtttg gagcttttca 21361 gaaaagtttc ctacgatgaa gtaataaaaa taaatgacga aataagggta agatttagag 21421 atgccggaca tatcctgggc tctgccatta ttgaaatgtg gattaacgag agaggcgaag 21481 agataaaaat tgtattttca ggagatttgg gaaacaagga cattccaata ttgagagacc 21541 cttcgataat tgaaagtgcg gattatcttg taattgagtc aacttacgga aacagactgc 21601 acaatgaacg ggtggacaaa gcggagtatt tcctcaattt gataaacagt acaattgaaa 21661 aaggcggaaa tgtcatcata ccttcttttg cggtgggaag aacccaggaa ctcatatatg 21721 agctgaataa aaagaaggaa gtatacgatg aaaaattgaa aatgctgttt gccacgccgg 21781 tttatattga cagccctatg gccatatctg cgacagaggt gtttagaaat aatctggact 21841 gttatgatga ggaagcaagg gaatatattg aaaacggtga caatcctctg gattttccgg 21901 ggcttcagtt tacccggacg gcagaggagt caaaggcatt gaatgagagg aaggaaagct 21961 cgataataat tgccgccagt ggcatgtgcg aggcgggaag aatcagacat catctaaaac 22021 ataacctttg gagaaaagac agcacgataa tttttgtagg gtatcaggcg gaaggtacat 22081 tgggaagaag gcttttggac ggagcgaaaa aagtaagact gtttggcgaa gagatttccg 22141 tggaagccag aatagagatg attgaaggct tttccggtca tgcggataaa gaagggcttt 22201 taaaatggat cgaaaggttt aacagaaagc ctaaaaaaat ttttatagtg catggcgaag 22261 aagatgcgat gattgagttt tcagaagaaa ttaacagaag attcaatatt gaaacggtga 22321 taccttccag aggggaaagc tttatattaa atgcccacaa tgtaattgca attgacgaaa 22381 aagtaagacc tgacaattcc ttcaggatac ttcaggtggt tgaaaagctt gaaaatatta 22441 aagaagaagt ggaagagttg tcctatatat taaagtcgga cttaaagcag gataaaaccg 22501 atcttgaact tgatgagttg atggcaaagc ttaagaatat agaaaaatca attttggagg 22561 ctttaaaata ataagtgtga aaatattaat atgttatgta aaaaaataaa gaagtttaaa 22621 attcttcttt atttttttgc cctttattgt acaataaaag tgaatcacag tagtatggca 22681 ggatggcagg tagtgaaatt tgattttttt ggaggatggt aggaatatgt ttatgaaatt 22741 cttgtttctt gctctcttcg ttgccgttat gatcggcgtc ggaatttaca gccggaaaaa 22801 aataaataac gaacaggact ttttattggg cggaagaaaa atgggaccgt ggatttcggc 22861 ttttgcctat ggtacaacat atttttcagc ggttattttc ataggctatg ccggaaaaaa 22921 cggatggaat tttggaattt ctgccgtttg gattggaatt gcaaatgcag ttttaggttg 22981 tcttctctcc tggcttgtcc ttgcaaagag aacccgtaag atgacgcatg atttaaacgt 23041 ctcaacaatg cccgatttct ttgaaaaaag atatgacagc aagggtttga aaatagtttc 23101 gtcaatcatt atcttcgtat tccttgttcc ttattcggca tcggtttacc agggattgag 23161 ttatttaatt gaaaaaacaa ttgcagagcc tttggctgcg acttttggaa ttacgatttc 23221 ttttgaggca attatgcttg taatggcagc gttgacggga atatatcttt tgcttggagg 23281 atatattgcc actgcaatta atgatttaat acagggcatt ataatgattc tcggaattat 23341 tttaatggtg gcctttgttg tgaatcacga aaatgtagga ggaattgccg aaggactgtc 23401 gaggctttca caaattccgg acgtgggaga agggctggtc aagcctttcg gaccgcagcc 23461 tttaagcctt ctttctttgg ttatacttac gagccttggc acttggggat tacctcagat 23521 gattcataaa ttttatgcgg taaaagacga tgattccata aagaaggcta ctattgtttc 23581 gacaattttc gcaacattga tatccggcgg agcttatttc ataggtgtct ttggaaggct 23641 ctttgttaca ctggatgaaa taggcggaga tcttgacagg attgtaccta ccatgcttga 23701 aaaggcattg ccggattatt tgatgggtat tgtaattatt ctggtgcttt cggcttcgat 23761 gtcaactctc tcttctttgg tgcttgtatc aagttcggca atttccatgg accttgtaaa 23821 aggagtattt ttcccgaaga tgaagagtga aaaggtcatg gttcttatga gaatactttg 23881 tgcattgttt gtggcatttt ccttcgtcgt cggtgtaaga cccagctcca ttttgacact 23941 tatgtcattg tcctggggaa ctgttgcagg ttcattcctt gctcctttct tgtacggcct 24001 gtactggaaa ggtactacaa aggcgggagc atgggcaggt atgatagttg ggttcttatg 24061 ctccgtggga ggttcaatga tttttggttt aaaaaatgca ccgaatgtgg gagcggcagc 24121 catgctcata tctctgatag tggtacctgt ggtaagcctc tttacggcaa agcttccaaa 24181 tgcgcatatt aacatgatat acggtgagga agacagtaag cagaaattgg cctcataaaa 24241 ggaaatatct taacataaaa tagaattaac gtaaaataga atttaatttg tatattgaaa 24301 aagcagccga agtttacttt tcggctgctt tgctttttat ggcggggcaa tggatctatt 24361 ttccgatttt aaaggttttc acttttggac tgcaggctgt ttacagcctt ttttgaaagc 24421 aattaataat tgacaataat ccgtcaataa aagataataa taaaagggtt taatatgctt 24481 gaattatgtg ataagataga aataatatta ttccattatt tatggttaga tgggggattg 24541 ttgatgaaaa aattaatgct cggaaacgag gcggtagcca gaggagctta tgaagcagga 24601 gtcagagtgg caacggctta ccctggaacg ccaagtaccg aaataacgga aagtatagca 24661 aaatacgacg aagtgtattg tgaatggtca ccgaatgaaa aagttgctct ggaagtagct 24721 ataggctcgg caattgccgg tggaagagca atttgttcga tgaagcatgt cggacttaat 24781 gtggcggccg atcctttgtt caccgtatcc tacaccggag ttaatgcagg actggttatc 24841 atggttgcgg atgatccggg aatgcatagc tctcaaaacg aacaggacag cagaatgtat 24901 gcaaaagctg caaaagtgcc catggttgag cctgccgaca gtagagagtg taaagaatat 24961 gtgaaggcgg cttttgaaat aagcgaaaaa tttgatactc cggttatttt cagactttcg 25021 actaggatat cccattcaca gagtgttgtt gaaatcggtg aaagagagga tgtaccgctt 25081 aaggaataca aaaaggatcc cgaaaaatat gtcatgatgc ctgcaatggc gcgtaaaaga 25141 catgttgcgg tagaaagcag aatggctgct ttggccgagt tctccaatac aactcctcta 25201 aacaggattg aatggggaag cacggatatc ggtgtaataa ccagcggaat tgcctaccag 25261 tatgcaagag aagccttcgg tgatgtctca tatctcaagc tcggaatgat ttatccactt 25321 ccggacaagt taattaaaga gttttccgaa aaagtaaaag tattatatgt tatagaggaa 25381 ctggaaccgt tttttgaaga gcatataaga aaactgggaa tcaaggttat aggcaaggat 25441 ttactgcccg ttacagggga atacagtgcc aaccttatca gggaaaaagt atttggaaaa 25501 caaatcggcg gaaagaaaat tgagggagtc caggttccgg tcagacctcc tgtaatgtgt 25561 ccgggatgcc cgcacagggg aatgttttat gtgttaaaca aactgaaact taccgtaagc 25621 ggagacatcg gatgttacac attgggagcg ttgccgccca cccaggcgat ggatacttgt 25681 atctgtatgg gtgcaagtat cggtgcggct cacggtatgg aaaaagcaag gggcagagag 25741 tttagaacaa aaactgttgc catactggga gattccacat ttgtgcattc gggaataacc 25801 ggacttattg acgtggttta caataaagga aattccacgg tgataatact ggacaactcc 25861 attaccggta tgacaggtca tcagcacaat cctacaaccg gttttacaat aaagggagaa 25921 cccacaaaac aggtggatct tgtaaagctt tgcaatgccg ttggaattga cagggtcaag 25981 gttgtagatc cttttaatat aaaagagttt gaaaaaaccg taaaagaaga aattgaagct 26041 gatgagcctt cggtcataat ttcccaaaga ccgtgtgccc ttttaaaaca tgtaaaattt 26101 gaaggcccgc acaggatagt cattgaaaaa tgcagaaaat gtaagatgtg tatgagaata 26161 ggatgtcctg ccattgttga catgggggac catatagaaa taaatgatgc tttgtgtgtg 26221 ggttgcaggc tgtgttcaaa agtatgtaat ttcgatgcga ttgaaaaggc tggtgaataa 26281 taatgaaaaa gtgtaatata atgatagttg gagtaggcgg acagggtact ttgcttgcca 26341 gtagaattat aggaaatgtt gcactgaaac aaaactatga cgttaaagtt tctgaagtac 26401 acggaatgtc ccagcgggga ggaagtgtcg taacttatgt aaagatagga gacaaggttt 26461 actctcccat aattgaaaaa ggtgaagccg acataattat ggcttttgag atgcttgaag 26521 ctttaagatg ggcggaatat ttgaaagaag acggcaagct cctggttaat gaacagaaga 26581 tcaatcctat gcccgttatc atcggaaaag aaaaatatcc tgaaaacata atgcaaatgc 26641 ttaaggaaaa ctataaaaat gttatttccc tggacgccct taaaatagcc agagagtgca 26701 aaaacataaa agcggtgaat acggttttga ttgggcttct ggcaaaggtg ctggagattg 26761 ataaagaagt ttggattgaa tcaattaagg aagtcgttcc ttcaaaagcc gttgatgtaa 26821 atcttaaagc ttttgaagaa gggtacagca gaggttgata taaatattgc cggcaaggcg 26881 gatatatcag gacagatata taaagtccac gggcgaagtg cccaaggtaa taatataaaa 26941 ttataatttt gtattggggg ttgtcgtatg aagtactgga atccttcatg tgaatgtatg 27001 tcaagagatg aaatgacgaa gcttcagacg gaaaggctga ttgagactgt aaaaagagtt 27061 tatcataatg ttccgttgta tagggagaaa atgcaaaaga agggcattga gcccggagac 27121 attaaaacgt tggatgacct gaagaaactt ccttttactt acaaagacga tttgagagat 27181 acatatcctt atggtatgtt tgccgctccg ctgagcgaaa ttgtaagaat acacgcttct 27241 tccggaacaa ccggaaaacc gacggtggta ggttacacga ggaaagacat tgacacttgg 27301 tcggaggtta cggcaagaac tttggtttca gccggtgcag acaaaaattc tcttattcag 27361 gttgcctatg gatacggact ttttacggga ggactgggaa tacactacgg tgctgaaagg 27421 atcggagcat cggttatacc tatttcagga ggaaatacaa aaaggcagat tcagataatg 27481 aaggattttg gtactactat tttggcatgt accccttcat atgctttgta tatggcagaa 27541 gtaatggaag aactcggtat caaaaaagaa gatttgaaac ttaaagcagg cgttttcgga 27601 gcggagcagt ggtctgaaaa tatgagaaaa gagatagagg aaaggcttgg aataattgcc 27661 atagatattt atggattgag cgaagtaatc ggaccgggag tttccactga gtgttattgc 27721 aagtgcggac ttcatgttca agaggaccat tttattcctg agattattga ccctgaaact 27781 ggagaagtgc ttccgccggg ttcaaagggt gaactggtat tttcaacgat taccaaggaa 27841 ggaattcctc ttttaagata cagaacaagg gatatttctt ctctcaatta tgaaaagtgc 27901 gaatgcggaa gaactaccgt cagaatgagc aaagtatcgg gaagaaccga tgatatgctt 27961 ataataagag gtgtgaatgt cttcccgtca cagattgaat ctgttctcct tgagtttgga 28021 gatactgctc ctcattatct gctgatagtg gacagagtgg ataatctgga tgtgcttgaa 28081 atatgggtgg aaatgaatca acagttgttc tccgatcagg ttaagaagat agaagacagt 28141 gagaaaaaga taagaaaggc catagaggag actcttggaa taagtgcgac agtaaagctt 28201 gttgaaccaa aaaccattga aagaagcgaa ggaaaagcca agagggttat tgacaagcgt 28261 aggttctaag ctcgctattt gagctgttgg aattattcca aaataaaaat ggagggataa 28321 gacatgcttg taaaacagat ttccgtattt ttggagaaca aatccggcag acttgctgaa 28381 gttacaagaa ttcttggaaa caacaacata gacatcagcg ctctgtcaat agccgacacc 28441 actgattttg gaattttaag actcattgta aatgacccgg aaacggccga aaaagttttg 28501 aaagataacg gttttacagt aagttgctgt gatgtgattg ccatttcagt tcccgacaag 28561 ccgggaggac tggcaaaagt gttaagtgtt ttggaaccgg agtccatagg aatagaatac 28621 ctgtatgcct ttgtgggaaa agcggaaaat gaggcactgg ttatattaag aattgatagt 28681 ccggaaaaag ctgtggagtt gcttgaaaaa gccggagtga aggtgttgga ttccaagacg 28741 gtttacaaac tctagtttaa acttgccaca aatccagagg atggtgttat ggacattaaa 28801 aaagagccac tggcatatag aatgagaccc aggaccctgg aggagtttta cggacaggaa 28861 gaaatagtcg gcgagggaaa gcttttaaac aggatgataa aggcagacag gatttcatcg 28921 attattcttt acggtccgcc cggaacgggt aaaacttctc tagcaaggat tattgccaac 28981 agtaccaagg ccaattttga aaaacttaat gctgtcactg ccggtgttgc ggatataaag 29041 aggattgtgt cggatacaca gaatccgata ttaaatccaa agggaagaac cgtattgttt 29101 attgatgaaa ttcacagatt taacaagtcc cagcaggatg cacttcttcc gtatgtggag 29161 gacggtacta ttatccttgt gggggcaacc accgagaacc ctttttttga agtcaacaag 29221 gcgttgattt caaggtcttc ggtatttatg ctaaaacccc ttggcagtga cgcaataaaa 29281 aagataataa gaaatgcctt aactgacaaa gaacggggtc tgggcaatat ggatattgaa 29341 atagaagagg atgcgctgaa ctttttggcg gatatatgtg acggtgatgc cagaatagct 29401 ttaaatgccc ttgaacttgc agttttgact tcccctgtcg gaagtgacgg taaatttcat 29461 attgatatac aactgattga ggaatgcatc caaaaaaaag ctgcaaggta tgacaaatcc 29521 ggtgaggaac attatgacaa tatcagtgct tttataaagt ccatgagggg aagcgatccg 29581 gacgcggcag tgttttatct tgcacgggcg ttgtatgccg gagaagatcc gatgtttctg 29641 gcaagaagga taatgatatg tgctgccgaa gatgtgggta tggcaaaccc agctgctttg 29701 caggtggcag ttgcagctgc gcaggctgtg catatggtag gtatgccgga ggccagaata 29761 attttgtctc aggctgcgat tatggtggcc accagtccaa aatcaaactc atgttatgtg 29821 gcaattgacc gtgctttgga tgatgtgaaa aacaaaagaa caggagaagt cccgatgcac 29881 cttagaaatg cggtgacatc gggaatgaaa gaattaggat acggaaaggg ttataaatat 29941 gcccatgatt atcccggcaa tatcgttgac caggattacc ttccgcaaga gattaagggg 30001 actgtttact ataatcccag cgcaaatggt tatgaattaa aaattaagga atggcttgaa 30061 aaaagaagaa acaagaggga aatataaata tatgtctatg ctttagagtg tataacaagc 30121 cataaagtta attttttata cagtctttca atatttcata caatcttcct gtgcaaagat 30181 ttttctataa agcttaaata aaataaacaa tctattctat ttatatattt atattagttt 30241 tatttatcag tctttgtggc aaatttgaga ttgagggcat cctgagcagc cgcagctgca 30301 ggatcccttt ttcctgtctt ttattatttt tacaatggcc aaaacggcta aacatattaa 30361 aacagcactt attataatat ttgcaagatt ttcagttata aatttaatca taattttgct 30421 cctcccaaca atgctcttga tatttttttc gtagaagaat ttttactgtc tttattatcc 30481 ggtcggcgaa gaagcagata aacaaatcct gcaaaaacta ctattgcaac agcagtgaat 30541 atattaaatc catgacctgt aaacagcata ccgaactgat atatgcaaag agaaaccgca 30601 tatgccaaac ctgtttgata gcctaccgct ataagggtcc actttgcatt cttcatttct 30661 cttcttatgg ctccgatggc ggcaaagcat ggtgcgcaaa gcaggttgaa aaccagcagt 30721 gaatatgctg aaagtgccgt aaatgaggct tgaaggttac cccagatttc tgcaccgtct 30781 tcggcaactt catgaaatcc gtaaagaact ccgaaagttc ctacgacatt ttcctttgct 30841 gcaaggcctg tgagcgttgc aacagctgct tcccaagttc cccagcccag aggaatgaag 30901 agcggagcga caatgtttcc caggccggca agcattgaat ctgacgcatc caccatttga 30961 agccgccagt taaagttgga caggaaccat acaagtgtgc tggcaaggaa tataattgtt 31021 cccgcttttt tgatgaagga tttggttttg tcccaaatat taagcgccac gttcttaact 31081 cccggtacat ggtaggcagg aagctccata acgaaagggg aggggtttcc tgacaatgct 31141 ttggttttct ttaagattat tcccgaacaa ataattgcgg cgatgccgat gaaataaaca 31201 gaaggagcta cccaaacgga cccggggaaa aatgctcccg ctatgagtga aataatcggc 31261 agcttcgccg agcagggaat aaatgttgtg gtcatgatgg tcagttttct gtcttcttcg 31321 ctttcgatag ttcgtgaagc cattatgccc ggaacaccgc atcccgttcc tatgataatc 31381 ggaatgaagg atttaccgga aaggccgaat tttctaaata ttctgtccat gataaaggca 31441 attcgcgcca tgtatccgca atcttcaagg agtgaaaggc acaaaaacag tactatcatt 31501 tgaggcagaa aaccaagtac ggatccaaca ccggcgatta taccgtcaac aattaaagat 31561 gacagccagt cagcacagtt gactgattct aagaagcttt ccacggcagt cggaatgatt 31621 tcaccaaaca acacatcatt tacccattcg gttgcccatc ctcctacagt ggtaactgat 31681 ataaaataga caaggaatat gacggcggca aaaatgggaa acgccagcca ccggtttgtg 31741 acaactttgt ctattttatc agatattgtg tcgcgggagg tgtttttccg cacatagcag 31801 tcttttattg cgtcaacgat atatttatat ctttcattgg taataatgct ttcgctgtcg 31861 tcatcaagct gtttttcgca tttggcaata atgttttcaa ttctggcttt ggtggcgtcg 31921 tccaaagaca gctcttccag tactttttga tcccgctcaa aaagtttgat gctgtaccag 31981 cgcagaaggt ccggactgac acgatcttta atacaggaag aaatctctgt caacgagtct 32041 tcgaccggtt tggaaaattt atgcctgggt gtcatctttg ctttttgctt tgcgagagcg 32101 attgcttttg atacagcttc ttttgaaccg gtacctttta aggctgaggt ttcaaccact 32161 tcacagccga acttttcaga aagcttttta atatctatgt tgtcgccttt cttgcgcaca 32221 atatcaatca tattaagtgc aataacaaca ggtatgccca tttcagtaag ctgtgtcgta 32281 agatataaat ttctttcaat atttgctccg tcgacaatat ctattattgc atcaggcttt 32341 tcatttatca aatagtttct cgaaacaatt tcctccggtg tataagggga gagagagtaa 32401 atacctggca ggtcggttaa aataacatcc ttgtgccctt taagtctccc ttcctttttt 32461 tcaactgtaa caccgggcca attgccaaca tactggttgc ttccggttaa atcattaaac 32521 attgtggtct tgccggagtt tggattgccg gcaagagcaa ttcttatcga catgtaattc 32581 cctcctcgta tttggttagt ttcaactaac cgcagggcac aattttgctc attacaaatt 32641 atgccactac tctacttcta tcatttctgc agcagatttt ctgaggctta actcgtatcc 32701 tcttacattt atttgaatcg gatcacctaa gggagccact ttgtggatgt aaatttcaca 32761 gcctctggtg atgcccatgt ccattatacg cctttttaaa gcgcccgtac catgcagctt 32821 gacaaccttg actgtttgac cgcatttggc atctctcaaa ctaaacattc atatcatctc 32881 ctttcctgga gaatatggct tcgtttattg tttatcaaac aagttagttg agactaactc 32941 tcgttcaaaa aaatatagtt agttaaaact atccgcttta tctactttta gtttagcaag 33001 gcagttttaa tttgtcaata aaaaatatgt taaatgcttc acaaattttt ttgatgcaat 33061 aatttttaaa agacaggttg ttctgcaatt cacaaatatg gtataaatag cataatttct 33121 attgttaaga agataaattt gtgataatat taaaatgtag tcctcttgtg tcaggtggtg 33181 atattgggtt gaaaattcaa gagtcggcag aaaattatct tgagactatt ctcatactga 33241 ggcagaggat aggtcaagtc agatccattg acatagtaaa tgagatgaat ttttcaaaac 33301 cgagcatcag ttatgccatg aagcagctta gggaaaacgg gtatatttca atggacgaat 33361 cgggatatat aacattgaca gaaaaaggac ttgaaattgc cgagcgtgtt tatgagcgtc 33421 ataaagtact tacggactat cttgtctctc tgggagtgga cgaggatgtt gcaaaggcgg 33481 atgcatgtcg catagaacat gttatcagtc cgatgagctt tgaaatgatt aaaaaagcat 33541 ataaagaaat cttggaaaac aagcaggcaa aaaaagaata aaaagaataa taaagaaaaa 33601 cagagcctca aattttgaca ttgaatttga ggcttttaaa tttttgcgga agtttattta 33661 cctgtatttt tttatatttt catcatatgg cgggtagata ataccttttt cggttataat 33721 tgctgaaatg tatttgtttg gtgttacgtc aaaggccgga ttccttacct ttacaccttc 33781 gggagcaatt ctgatgcctt tgatatgagt tatttcagca gggcttcgct cttctatcgg 33841 aatttgctct cccgtttcta tggaaaagtc aatggttgtt gtgggagcgg caacatagaa 33901 cggaatattg ttttcctttg ccaaaacagc aagggaataa gttccgattt tgtttgcagt 33961 atctccgttt aaagctattc tgtcagctcc gactattaca caatctatta atccttcttt 34021 catgaaatgc cctgccatat tgtcgcatat aagcgttacg ggaatattgt cctgcatcaa 34081 ttcccaggcg gtaagccttg caccctgaag ataaggcctt gtttcgtctg caaaaacctg 34141 tatgtttttt cctgactcat gagccgcccg gataactcct aaagcagtgc cgtagtcgca 34201 agtcgccaaa gcgcctgcgt tacaatgggt gaggattgtc caattttctt ttatcaactc 34261 attgccgaac cggcctatgc ttctgttgga ttcaatgtct tctttttcca tgaggtatgc 34321 ctcttcttca atgagttttt tgatttcctc tatggtcttg tcccggtttg agacggctct 34381 actgtacact ctgtcaacag cccagaacag atttacggct gtagggcgcg tgcttttaat 34441 tatatcacac acctttgcaa gttcggcaaa aaattcttct ttggaatcag tatttattgc 34501 ctttgaagct attgccacac cgtaggcggc agttacacct atggcgggag cacctcttac 34561 aatcatattt tttattgcat cggcaacctc aatatagttt ttcagttcta caatcttttg 34621 ctctcccgga agcaaagtct gatccaataa ttttaatact ccgttacaat attccaatgg 34681 tttcataagg ttctcctttt caaaatgtaa taaacaagtt tgtttttaaa ctacaggtcg 34741 agaccgctta aatccacgtt gcagcatgtg caattgctgt tttcaaggtc aattctttta 34801 attacttcaa aaagcatgtt tttaactttt tcattgtttt ccgcaaatac tttcagcaca 34861 gcctcttcgg taacgggctc aatgtcgtcg cggccttcga gacctgcgtc atagtcggtg 34921 ataagcgcta tgttggcata gcagataccc agctccctgg ccagataaac ttcagggtac 34981 tgggtcatgt taattacatc ccagcccatt ttgctaaacc atctgctctc tgccacagtg 35041 gaaaatctcg gtccctggat gacaaccacg gtaccttttt cgtgggttgt tattccaagg 35101 tctttgccca cctgaattgc aatttttcta agctcggggc agtaaggatg agcagagctt 35161 atatgcttgg ttacaggccc gtcgtaaaat gtgtctttac gtcctgttgt cctgtcgaca 35221 aactgatcgc agataacgaa atctcccggc tttatatcgg ctctgagact tcctgaggat 35281 gtgggagcca gtattttttt tactccaagc tttttcatag cgtagagatt tgctctgtaa 35341 ggtatcatat gaggcggaaa ttgatggttt ttgccgtggc ggggcaaaaa agctattctt 35401 ttgccttcat aggttgcaat tgcaattttg tcgcttggtt ttccgtaagg agtttccatt 35461 tctatttctt caacattttc aagaaaagaa taaaaacctg aaccgccaaa aacgccaata 35521 tcagctttat aattcattgt aaacctcctg aaaaatttat tttaatataa aaaatttatt 35581 ttaatataac ttattatatt tataaaagta taaagtttca attatattat tgaatttact 35641 ttgttaaatt gcatatgccc gggcttccat cataaacctt caataaaaat agttttttca 35701 aggcaatcta aaaataatat tatcaataaa attcttttta aaatttttgt ttccgtatat 35761 ataaaaaaac attgcacatc gaatattata aaggaggaaa atggagtgga tgacagcaaa 35821 aaagagtttt tcaggcaact gcttgtggaa gagaagaaga atatagaaag aaccataaat 35881 cttatggagg aacatgggat atcaaagcaa aatgtggaat ctgccgatga gctgtccggc 35941 tatgacaatc accctgcaga attggggaca cagctttttc agacagagct caataacgct 36001 ttgaaggttc atgaagaacg tttgttggaa gatattaatg aagctttaac aaaaatggac 36061 aaaggaagtt ttggaaaatg tgaattgtgt ggaaaggaaa ttgatgaaga aagacttgag 36121 gcattgcctt atacaagact ttgcatagat tgtgaaaacg ccaaagagtc atctgacgtg 36181 aatttagaca gacaaaggcc ggtggaggaa ttgatttggg atgcgccttt tggaagaaag 36241 tacctaaata agcaggaaga tgacgaaaat gaaggtatgg accagtttaa cgaccttgta 36301 aaatacggtt catcggacac cccacaagat atggggggct attatgattt tgatgaatat 36361 tacacgaatg agttggacaa acaggggata gttgatataa tggataatat ttctaatgag 36421 gaatataaaa aacaattgcc ttaagtattg tttgaactac agccttcatt tatccaataa 36481 ggaatatgaa acgacgtgaa ttcttatttg ggtatttgta taaatatttt tttataaata 36541 tttataaaaa acatgtaaga ttgataaatg aaggcttttt atattatttt ttgtaattat 36601 tgcattttgc ccccttaaaa aattttaaaa ttcgaaatta atttttgcgt atggattgtg 36661 caataaaaat atgataatat ttaggtgaat ataaaaaaat tgtattaatc aattgcttac 36721 aggtataaaa attaagaaaa ttgcgcactg tgttggcgta accttaatca acaattggaa 36781 atggggtttg ggaagtatac ttggaagcaa ctggttatta ttgaaattta cagacgatgt 36841 gaaagactgt gaacaaacca atcaatgccc aaattatact ttgcagcaaa atcatccttg 36901 catatccctt cagatttaaa agccgcgaca attagcgttt ccgatgaagc tcatttatgt 36961 gaacctcgat tccttcctat aaaatttact ctattttcat ttcaattttt ccagtttgca 37021 tgtggaatta tttcccgaag ctccgtattt ctgttgttga tggtttgtat gtcaacatat 37081 gcgtgcattt taatataaaa tgaattgtta aaggagtgtg aaatatggca aagagaagat 37141 tatcgctact tttggtactt gccataatgt ttacgatggt cgttccacag atatctgcaa 37201 gtgccgaaac agttgctcct gaaggctaca ggaagctttt ggatgtacaa attttcaagg 37261 attcgcctgt agtcggatgg tcaggaagcg gtatgggcga gcttgaaact atcggcgata 37321 cccttccggt tgataccaca gttacatata acggtttgcc gactttaaga ctgaatgtcc 37381 agacaaccgt tcagtcagga tggtggattt ctcttcttac attaagagga tggaacaccc 37441 atgacctttc ccagtatgtc gaaaacggtt atcttgagtt tgacatcaag ggtaaggaag 37501 gcggagaaga ctttgttatt ggtttcaggg acaaggttta tgaacgcgtt tacggacttg 37561 aaattgatgt taccacagta atatcaaatt atgtaacggt aactacggac tggcagcatg 37621 ttaagattcc tttgagagac ctgatgaaga ttaataacgg atttgatcct tcatcagtta 37681 catgcctggt gttctcaaaa agatatgcag atccgtttac agtatggttc agtgatataa 37741 agattacatc agaagacaat gaaaagtccg ctcctgcaat caaggtaaac cagcttggct 37801 ttattcctga agctgaaaaa tacgctttgg ttacaggttt tgcagaagag ctcgcagtat 37861 cggaaggtga cgaatttgcc gttataaatg ctgcggacaa ttctgttgct tataccggaa 37921 aattaactct tgtaacagaa tatgaacctc ttgattccgg agaaaaaata cttaaggcag 37981 atttcagcga cttgactgta cctggcaaat actacattag tattgaaggt cttgacaatt 38041 cacccaagtt tgaaatcggt gaaggtattt acggtccact ggttgttgac gctgcaagat 38101 atttctatta tcagcgtcag ggtatagaac ttgaagagcc ttatgcgcag ggatatcccc 38161 gcaaggacgt tactcctcag gacgcatatg ctgtatttgc atccggaaag aaggatccga 38221 ttgacataac aaagggttgg tatgacgcag gagacttcgg taagtatgta aatgccggag 38281 caaccggtgt ttccgatttg ttctgggcat atgaaatgtt cccttcccag tttgttgacg 38341 gtcagttcaa tattcctgaa agcggaaacg gtgtaccgga catccttgac gaagctcgct 38401 gggagcttga atggatgctg aaaatgcagg acaaagaaag cggaggattc tatcccagag 38461 ttcaatctga caatgacgaa aacataaaat caagaataat cagggatcag aacggctgta 38521 ccactgatga tactgcatgt gccgccggaa tacttgctca tgcatacttg atttacaagg 38581 atattgaccc tgattttgca caagagtgcc tggatgcggc aataaatgca tggaaattcc 38641 ttgaaaagaa tcctgaaaac attgtttcac ctccgggtcc atacaacgta tatgacgaca 38701 gcggagacag actctgggct gcagcttcgc tgtacagagc taccggtgaa gaggtttatc 38761 atacatactt taaacaaaac tacaaatctt ttgcacaaaa gttcgaaagc ccgactgcat 38821 atgctcatac atggggtgat atgtggctta cggcattcct ttcgtatttg aaagctgaaa 38881 acaaggatca ggaagttgta gactggattg atacagagtt tggaatctgg cttgaaaaca 38941 tactcacaag atatgagaac aatccatgga agaatgcaat tgttcccgga aactacttct 39001 ggggaatcaa catgcaggtt atgaatgttc cgatggatgc tatcataggt tcacagcttc 39061 ttggaaaata cagtgacaga atagaaaaat taggttttgg ttcacttaac tggctgcttg 39121 gtacaaatcc gcttcgcttc agctttgtat caggatatgg agaggattct gtaaaaggag 39181 tattcagcaa tatttacaat acggacggca agcagggaat tccgaaagga tacatgcctg 39241 gtggaccaaa tgcttatgaa ggtgcaggcc tgtcaaggtt tgcagcaaaa tgctacacca 39301 gaagtaccgg tgactgggta gccaacgaac atacagtata ttggaactca gctttggtat 39361 ttatggctgc ttttgcaaac cagggttcag aggttaatcc gggacctgcg ccggaaccgg 39421 gagtaactcc gaatcctaca gaacctgcaa aagtggttga catcaggata gatacttctg 39481 ctgaaagaaa gccaatcagc ccgtatatat acggaagcaa tcaggaactt gatgcaacag 39541 ttactgcaaa gaggttcggc ggaaacagaa ctacaggata caactgggaa aacaacttct 39601 caaatgcagg aagtgactgg ctgcattaca gtgatacata ccttttggag gacggcggag 39661 tacctaaggg agagtggagt acacctgctt ctgtagttac cacgttccat gacaaggcac 39721 ttagcaaaaa tgttccttac acacttatca ctcttcaggc agcaggttat gtttccgcag 39781 acggaaacgg accggtttcc caggaagaaa ctgcaccgtc ttcaagatgg aaggaagtta 39841 agtttgaaaa gggagcacct ttctcactta caccggacac agaagatgat tatgtttaca 39901 tggatgagtt tgtaaactat cttgtaaaca aatacggaaa tgcatccaca cctacaggaa 39961 taaagggtta ttcaatagat aacgagccgg cattgtggag tcatactcat ccgagaattc 40021 atccggacaa tgtaactgcc aaagagctta ttgaaaaatc tgtagctctt tccaaggcgg 40081 ttaaaaaggt agatccatat gcagaaatat tcggacctgc tttgtacgga tttgccgcat 40141 atgagacact tcagtcagct cctgactggg gaactgaagg agaaggatac aggtggttta 40201 tagattatta cctcgataag atgaaaaagg cttctgatga agaaggaaag agacttttgg 40261 acgtacttga cgtacactgg tatccggaag ccaggggcgg cggtgaaaga atatgctttg 40321 gagccgatcc aagaaatatt gagacaaaca aagcaagatt gcaggcgccc agaacattgt 40381 gggatcctac atatattgaa gacagctgga taggacaatg gaagaaggat ttcctcccga 40441 tattacctaa tcttttggat tccattgaaa aatattatcc gggaacgaag cttgctataa 40501 ctgaatatga ctatggcgga ggaaatcata ttacaggcgg tattgctcaa gccgatgttc 40561 ttggtatatt cggtaaatac ggtgtttacc ttgcaacatt ctggggagat gcaagcaata 40621 actatactga ggccggtata aacctttata ccaactacga cggcaaaggc ggcaaatttg 40681 gagatacatc cgtaaaatgt gaaacgtccg acatagaagt aagctctgct tatgcatcca 40741 ttgtcggtga agatgacagc aaactccata tcattctttt gaacaagaac tatgaccagc 40801 cgacgacatt caatttctca attgacagca gcaagaacta cacaatagga aatgtatggg 40861 catttgacag aggaagctcc aatattactc aaagaactcc tatagtgaac ataaaggaca 40921 ataccttcac atatacagta ccggctttga cagcgtgcca tattgtgctt gaagctgcgg 40981 agcccgtagt gtacggagac ttgaacaatg actctaaagt aaacgcagta gacattatga 41041 tgctcaaacg atatattctc ggaataatag ataatataaa tctgacagca gctgacattt 41101 attttgacgg tgttgtaaat tcaagtgact ataatataat gaagagatat ttgttaaagg 41161 caatagaaga tattccttat gttccggaaa accaggcacc taaagcaata tttactttct 41221 cgcccgaaga tccggttact gacgagaatg tagtgttcaa tgcatcaaat tcaatagatg 41281 aagacggaac aattgcctat tatgtatggg atttcggtga cggatatgaa ggaacttcaa 41341 caacaccgac tattacctat aagtataaaa accccggaac atacaaagta aaactgattg 41401 ttacagacaa ccagggggct tcaagttcgt ttacagctac cataaaagta acctcagcta 41461 ccggggacaa ttccaaattc aactttgaag acggcacgct gggaggattt acaacatccg 41521 gaacaaatgc tacgggtgtt gttgtgaaca ctactgaaaa agcattcaaa ggcgaaagag 41581 gtcttaaatg gactgtaaca agcgaaggag aaggaactgc agaattgaaa cttgacggag 41641 gtactattgt agttcccggt accactatga cgtttagaat ctggatacct tccggtgcgc 41701 ctattgctgc catccagccg tatattatgc ctcatacacc tgattggtcg gaagtcctct 41761 ggaattcgac atggaaagga tacaccatgg tgaagaccga tgactggaat gaaattaccc 41821 tgacactgcc ggaagacgtg gatccgactt ggccgcagca gatgggtata caggtacaga 41881 ccatagatga aggtgaattc actatctatg tagatgctat tgactggtaa gaaatttaat 41941 tggtcaaaca aaaatcaaat cagttgcaag ttataaggcc gggcaaaaaa ggaggaacct 42001 ttgcggtttc tccttttttg cttttaaaat ttttttatcg agattagttc aaaaaacaaa 42061 aacgggaaac aggatttgac ccacttaaaa atgtgtatgt gcacggattt ctatttggag 42121 ggaagcagaa attcataaaa actttaaaaa tcttattaag tttggctgtg taaagagaga 42181 tggagttatg atataataat atttgaataa tattatttat atcattaaac agtttaaata 42241 aataagcact atgcaaaaca aaacgccaat cagtttccat ggtggtttcc gctttctata 42301 cagcaaatct attttacaca tattctccat tttgattgaa gcaagttttg tagttaaatg 42361 ctatgggaaa gttataattt ttatataact ttgttattga ttttttatat tttttcctta 42421 tggaggtgat tttgtaaaat acaaacaata aatataatca aatatattat taaattattt 42481 tgaaggagga atcatggtga aaaagacatt atgctttgta ctgactttgg ctatgctgac 42541 ggcatttatt cttcctcagg ggattgtgtc cgcagcagga agctataact atgcggaagc 42601 acttcagaaa gccatttact tttatgagtg tcagcaggcc ggccctctac ctgaatggaa 42661 ccgcgttgag tggcgtggcg acgcaacaat gaatgatgag gtacttggtg gatggtatga 42721 cgcaggtgac catgtcaagt ttaatctgcc tatggcgtat tcggcggcaa tgcttggctg 42781 ggctctttat gagtatggcg atgacattga ggcatcgggg cagagacttc atcttgaaag 42841 gaaccttgcc tttgcccttg actatcttgt tgcctgcgac agaggtgaca gtgtcgttta 42901 tcagataggt gacggtgccg ctgaccataa atggtggggt tctgcggaag ttattgaaaa 42961 agaaatgaca agaccttact ttgtaggaaa gggatccgcc gttgtaggtc agatggctgc 43021 agctttggct gtaggttcca tagttcttaa aaatgataca tacctcagat atgcgaagaa 43081 gtatttcgaa cttgcagatg caacaagaag tgacagcact tatactgctg caaatggttt 43141 ctacagttcc cacagcggat tctgggatga gctgttgtgg gcttccactt ggctctatct 43201 tgcaacaggt gatagaaatt atcttgataa agctgagtcc tatattccaa aattaaaccg 43261 tcagaatcag accacagata tagaatatca gtgggcacat tgctgggatg actgccacta 43321 tggagcaatg atcttgcttg caagagctac aggtaaagaa gagtatcaca aatttgcaca 43381 aatgcatctg gattggtgga cacctcaagg ttataacgga aagagagttg catatactcc 43441 cggcggactt gcgcatcttg atacctgggg accgttgaga tatgctacaa ctgaagcatt 43501 cctcgctttt gtatatgccg attcaataaa tgacccggct ctcaagcaaa aatattataa 43561 ttttgcgaaa agccagattg actatgcatt gggttcaaat cctgacaaca gaagctatgt 43621 agtcggattt ggaaacaatc cgccacagcg tcctcaccac agaaccgctc atggaacttg 43681 gttggataaa agagatattc cggaaaagca cagacatgta ctttacggtg ctctggtcgg 43741 aggacccgga agagatgaca gttatgaaga caatatagag gattatgtaa aaaatgaagt 43801 tgcctgcgac tacaatgcag gttttgtagg cgcgctctgc agattgactg ctgaatacgg 43861 cggaactcct cttgcgaact tcccgccacc ggaacaaaga gatgatgagt tcttcgtaga 43921 agcggctata aatcaggcaa gtgatcattt cactgaaata aaagcattgc tcaacaaccg 43981 ttcatcctgg ccggcaagac ttattaagga cctttcatac aactattata tggatttgac 44041 tgaagttttt gaggcaggtt acagtgttga cgatattaaa gtaacaatag gctattgcga 44101 aagcggtatg gatgtcgaga tttcgccgat tactcatttg tatgacaata tttattacat 44161 aaaaatatca tatatcgacg gaaccaatat ttgtccgata ggtcaggaac agtatgccgc 44221 tgagcttcag ttccgtattg cggcacctca aggtactaaa ttctgggatc cgacaaatga 44281 cttctcatat cagggactta ccagagagtt ggcaaagaca aaatatatgc ccgtttttga 44341 cggagcaaca aaaatctttg gagaagttcc aggcggcttt gaaccggttc cttcaccttc 44401 gccgactcct gctcaatata aagtcggtga cttaaacggt gacggagtgg ttaattcaac 44461 tgacagtgta atattgaaaa gacatataat taaattttct gaaataacag atccagttaa 44521 attgaaagct gctgatctta acggagatgg caatataaac tccagcgatg tttcattaat 44581 gaagagatat ctgctccgta taatagataa atttccggta gaatagtttg gcatttgaaa 44641 tactctttga gtacgggctg tcctgaaaaa caggacggct cttttgttta tttttattaa 44701 tgttgagaat tgaaataaaa taattatcat ggtatacttt ttcattatat ttcttcattt 44761 gacaagttta gcgtgaagaa ttttaatttt atcggagaat gtttgagcaa gaggaaatat 44821 gatgtgaagg gtgagtgtaa tgaagttata ccttgttgcc ggttcaaaaa gcgatatgct 44881 gaaaagatcc ctggaagaaa accaggatat tgaagtggta tatattgcaa actcttttga 44941 agaagctctt aatcatttga ttagaaacag cctggatttt gacagcatgc tgttgatgga 45001 tgccggcatt gtcgaaaata cagaaagttt tacggatacc ctgaacactt taagagagtt 45061 gatgaacagc tcatatccaa atattacaat aaagttcatt acaaaagatc cggtatatct 45121 taataattac aataatattg tgtccgggga cgataggttt gaagtgtatt ttgttgacaa 45181 tgtgagaata ccgatatcat atattcagga agtctgcttg aagaaccaga acaaaaaatc 45241 ttcaagaatt caacctgtgg aaaaacaagt tgcggatgac tcttccaaaa cttctgacga 45301 gaaacttact caaacattga ccgcaaagtc aaagaccata tttggagtga gattgccgtt 45361 tttttcaaaa tcaaacgcga gtgaagaaaa acttgaaaat ggagaaacaa ataattctat 45421 aattggtagt tatgtacagc caaaacagaa aatttctctt gtttccaaag acttcagaaa 45481 agtgattgta gttaccggat gcagaggagc gggggctaca agcacggcag caaatcttgc 45541 cattgagtcc agtgcgcagg ggctttctac aatactggta gacatggata tccaatacag 45601 aggtgtaaat ttgtatttcc cgaaattcgg agatgaagtg gaatataatc ctgatttgtc 45661 ctattcgctg gtcaggtgtg ttataaagcc cgattcttat gatataaatt cgtgcagaat 45721 caatgacaat ttgtttgtta ccactttggc ttattcaata tcctcgaaag acaagctgct 45781 ggagataatt gacctgaaaa aactttcggc ttttataaat tttttaaggt tgaaatttaa 45841 cgtggtttta attgatatgc ctataagtac tctaagtaaa tattcccagc tgctgacgca 45901 gatagacagc atagccttgt gtgtaaacaa taatttgtat tcggtaatca gtaccgtacg 45961 gactgtggaa gacctatttg tcaaagagga cttggttttg tttactgtta aatcccgacc 46021 tgtgttgaca aaatataacg aagccaacag gcataacggc aaaactttca ctccggaact 46081 ggcatgcaaa attatatgcg aattgggagg atacaacagt gatttaactc ctgccgggat 46141 tgttccgtat tccagggaat ttgaccttca aattgattcg ggacaaaaga ttacatcgac 46201 aaacaaagtt tacaaaaatc attattttac aatacttaaa aatttgttgt aaagctcaat 46261 agagttgtgt tatataaaag ttttttattt attattgaaa aagattcctg tagttagtat 46321 aatctatatt atgagagtac aaaaactgtt attttatgtt ataatttata aaaaaaaagc 46381 gggttttatt taaataaata ggacataagc tttttgctat ttttcgtagg gggggataat 46441 atggatatta acagcataaa aagtataaag cccggcaatc aacttcctaa aaaattgttg 46501 gcgatatttg taagcgtggc ggttattatt ggttcattta tttatttaaa cagcgtaaat 46561 gattctgcaa aggatactgt tgatattgtt gttgtcaagg cttccggagg tatacctgcc 46621 aacactctca ttacaaaaga taatattggg aaatattcta ttatcagaaa agaatttaat 46681 gatgacatga ttacttatga taaagtggac agcattctta acaaatacag cctgtattat 46741 ttaagaaacg gggctcctat ctattatgat cagcttacgg acgaaaaacc gcgtgatact 46801 gaatggctgt atgatttgga agagaattat gaagttctta ccataaagta tgattatctt 46861 gaatgcggtg gaagcatact gcggccggga gatctggtaa gagtcagggt tacatataca 46921 gaagagattc cgtcgtcgga cggtatgatg tacggcggtt cgaaaaaagt aaagaaaact 46981 gagatattgt ttgacagtat tcgcgtaaag gatcttatca actcttcggg acgctccata 47041 tatgaagttt tgaaagaggt tttcaagcta agtgaaaaag acagacggga agtaatgaaa 47101 agccgtgatt ttatgcagag cattaaggct gaatcattgc ttctggcggc tacagaggag 47161 caggtaaaca aatttgcaaa atttaagtct caacaggatg ccgtatttac ttttaccatt 47221 ctgtcgagaa atggaaacga tgaagtattt gaccagcttc ctgtagttga gaaggaggta 47281 gagtcgtgga taacagagag cgaagcgaag gattagagct aaagtccctt cttgagaagt 47341 tgtccccgag agataagata tataacgaaa tggagacaaa taaaattatt gataatgtta 47401 tagggtttat tcccgcctcg gattgtgcgg attcttccat tttgcttgtg aatctggcgg 47461 tggcaattgc tcaaaaaggg tttaatactt gtattttgga tgccaaggtt ttttacccga 47521 acatatacaa gctgcttgat tgcgaagcaa atgcggcggg aaagggtctt ataaggattt 47581 gcagaagtga taaggttgac ataagagatg tgataaatga gaccaaatac aagaatttat 47641 atctattgtc tccaagtccc tctgatccta tggaggacta ttttgatttt caattggatg 47701 atgtcgacag ggttataacc accctaaagg agacttttga ttttgtgctt atagatattc 47761 cgaataatcc gccgttggag ttttgcattt cgtccgtcaa gaattgcaac gtgggatttt 47821 ttatatggag tgaacgtatt gactgccctc aaaataccag cagatttttg gagtttgtgg 47881 gatcattggg aattggtgta tcgaagctta tgaatgtgat tttaaataat ttatacggtg 47941 tcaaatttga caaaacaata atagaagata tgaaattgaa gcttattgcc gaatttccgt 48001 ttgtgtcagg cgccattgat ctttcgcttg aaggaagggt gtatatcgct gacagcctga 48061 taatcaacaa aaagtacaag gaatcgatga attcgttggt taatatattg acgaaaaagt 48121 aactgttttt tggagggttt gtaatgttat cgagaagtac tgtaagtgaa cttcaaaaga 48181 aagcaaagta tatacataga accaatactt caggaagcaa gctcacatcc atgacttttg 48241 aagaatgtct aaagcagtgt cagcagtata taagcaatgt ggcgacaaat tattacagaa 48301 gaattgaaga cccggccaaa aagagggaaa tgacggaaag gtatataatt gactatgttg 48361 aaacacagaa gcctgaagtg gaaggatttg aggaactttc ggccttaaga aatgccctta 48421 ttgatgagat tacccaatac ggtccgataa cagatgcgat ggaagaccct ctaatagacg 48481 aaatcagagc caatggtccg cagcagatat ttgtagagaa aaagggtaga accgagattt 48541 gggacaaatg ctttaccgac agggagcata tggaaagaat aattgcaaag cttattggag 48601 tatccaaggt gaggcttacc ccaagaacgc caatggtaaa tgcccgtacc atagaaggct 48661 acagggtcaa tgccacccat gcggatattt caccttacgg caatccggcg tttgtggtaa 48721 gaaagtttaa aaagtacact ctgactccgg aagagatgat aaaggaaaaa tcattttcag 48781 ttaatatgta caagcttctt tcgcttatac ccaaggccaa tctttcctgg atgacggccg 48841 ggcctaccgg cagcggaaag accactttga atgaagtttt gataaagcat attgatccgc 48901 tgtgtcgtat tataacaatt gaaaaccctg cagagtacag gctgctaagg tacaaaaacg 48961 atgaccccaa tgaaagggtt ataaatgacg tgcttcagta tgagtgtgtt cctgatgatg 49021 acgacagcag tccggcaaca atggaaaatt tgttgataaa tgccatgaga cagtctcctc 49081 actggatagg tcccggtgag cttcgttctc cgggagagtt tgagactgcc ctgcgcgctg 49141 cgcaaaccgg tcactatttc tttacaaccc tgcatgcgga aggagaccag gaagcaattt 49201 acaggttcct tactgcttac cttataaaat caaaagaacc tgcggaactg gccctgagaa 49261 atatatgtac cgccgttaaa tttgtcatat tccaggaaaa gctggccgac ggaacccgta 49321 aagttacatc aatttctgaa gtcagaggtt ctgaaggctt aaagcctatt attaaccaga 49381 tatacaaatt tattcctgag gatgttgatg aggatcctgt tacagggcaa atcagagcaa 49441 tagtaggcaa gcacaagaga gtaggccgta tatcggatga gcttgttgac agaatgatga 49501 aagcaggaat aaaaaagagt aagtttgaat tcctcacgcg tccggttgac cccgatgaag 49561 aggaggttta cgatatagat gctctttaac gtacttttta gtgtagctat tggattggtg 49621 attttgtaca tattgaatgt ggtgctggat cttaggcttc ttaacgattt gaaaaagctt 49681 gtcagttata tagtagactc catagcaaac cataacacga agaaatatct tgagaggata 49741 aaaagaagta aaatagtcaa gacaaatgac aacattatat caaaatacaa caggctggtg 49801 gagaatataa ttttcgatta taatctgccg ctgacattgg aaggatttaa ttcttttatc 49861 agtatactct ttgcaatact ggttttgata gttgtgcttt ttttaaagga tattacgctt 49921 tcagctttgg tttccatatc tttactggta ggcgcaatta catattttac tatgagatct 49981 agaaatctga aagccgctaa aattgagagt ataatggatg ccgaagacct gatatgtcct 50041 ctggcaaggg acggagttct tgtggcgata aaaaaagttt tggagtctga cgaatatatt 50101 aatgcagata taaggccgtt ttttgttcag tttgtggaaa actgcgaaaa ctacggttat 50161 tctttcagaa gagcaatgga aatactgaat cgccagttgg ggccgaagtt tgacaacttt 50221 gcgaaaaaag cggttatttt tgagtacaac gaacgtaaag gtatggctga tattttcctt 50281 gatattgttg aagaaaatgc tgctttaaga gaaataaatg caagaaaaaa cagaatcttt 50341 aaaaagatga acatgaactt tataatgaaa actgcattga tagttatatt tgttgcgtat 50401 tcgatgacag ttccggaatt aaggattttt atgctggaaa gtacagcggg gcgctttatc 50461 cttacgatga ccatagtggc catctgttta agctttgcca ggtgtcaggc attgcaagcc 50521 gatattggaa gttttggagg ggataataaa tggtaatact ctccaaactg tgtgctttgg 50581 cagcaataat ttatcttgtt ttcactttaa tataccctct ttttaaaccc atgacccgca 50641 aaagaaaaga gcattccagg gattttataa agcgaaagag gaatcagaaa aaggttgaaa 50701 aatatttgta ttttaaggat atagtgttaa gaagactttc caataaattt ttccttagtg 50761 acataaaaag aaatgaactt aattttttga taaaaaggct ggacttgaaa ataacaccgg 50821 aagagataag attgaagcag attttgtatg ttataggtgc cgtaggaata tccttgattg 50881 ccatgaacat taacaccctt attggctatg gatgtttgat atttgttgtg ttgggatggc 50941 tctatccggt tgatgaactg gaaaaaatga ttgaaaaaaa gaacaacaac atattggcag 51001 actttccttc attctacaac atgctttact atcaatacgc cagatccata aacatatatt 51061 tggcggatgt ggtcaaggac tttcttccca atgccaatga ggatatggct gcagaactgg 51121 aggtttttct tgacaatatt gagtatggag aggaatatgc attaaaacag ttaaaaaaac 51181 gtgttccgtt aagacacatt atcaagtttt gtgatataat ggaaacaaga ttgagaggat 51241 acgacaatat ttctcagatg acatatttaa agaatgagct ttatgattta agagttatgt 51301 cccttgaaga tgaactgcac agaagggagc aaaagaacgc gaggatgcag tttgttttaa 51361 ttgttgtatt ggcgatttac atcgtgatct actattactt catgtttgtt gatgccatca 51421 gaatgtttag ctagtcgttg gttatatttt tacatataaa aataatatat ttagaaaaat 51481 aagggggtaa ttataatgaa taaaaaatca aaaaaggatg tattgaaaaa ctcaatcaaa 51541 aaatttttga aagatgagag aggagaattc ggagtaaagc agattgctta caccgtagcg 51601 gtgatagtgg ttgtaggact tgttctcgct atattgaggg atcagatgga aggtatagta 51661 actactatat ggaatttctt gtgggagaaa attcaggatc tgatgggtta ataaattgta 51721 tgtaaggagg ttagacccgg cggtattaac gaaaccgggt gattttccat ggcgggtttt 51781 gcaaaaagtt tggtaattgt gctcatagtt tgcgttgtat ttttgataac aacgaatttc 51841 atatttttct ttccctggta catgactttg gcctatgaga catacaattt atccacattg 51901 gcggcacagc acaactatat agacagggat gaggcgcaaa tgatacttga caacctgaac 51961 aaaaaacctt ttttcaagga aaaccctgtt acttttgatg atatagatgg agaaaccgag 52021 cctggaaagc tgcaaagagg agagcagttt actgttagca taacggcaaa gtatcccatc 52081 cgtatggata tgggaattgt taacataagg agagactggc ctgtaacttt ttcggtggag 52141 acaacgtgcc tgtattatga taaaaatttg gacccgctgt ataaaagtga tgacctgatt 52201 tttgacgagc caatatatga tgaaccaata tattatgatg agccggcata tgacgatcca 52261 tcatatactg gtccgacaga agatgagcca ttatatgatg aaccggcata tgatgatcca 52321 acgcatgctg tgccgacaga aggtgctcca ccatttgagg agccgatata actgcaaaaa 52381 ggtgatacta tgagaaattt ggcaatagca atcctgatta ttgtagttgc gtcaatgttg 52441 tttcaaccct ttttcgaaat ggttgaaatt ttcgctgaaa aggcacagat agattctgcc 52501 gttgagtcag cggcgaaatc cgcacgattg acaggcttta agttgtcgga tatcagagat 52561 ttggaaaaaa agtttaattt tgatatggac agtgaagatg aaaactttat cagcgtattt 52621 tgtgatgtat ttgccgcaac ccttaatttg gagtttttat atgtgattga taataaagca 52681 tactttaaat caaataatga aagatataat gattttgtgg ttgaattcca atatgacaaa 52741 gattatcccg acagatgtca cgttattgtc acgacgaatt ataaatttaa aagaaattac 52801 ttaaagcaat ttgtagggga taattctttt gaactggtaa gggaaagaac attgtttgcc 52861 cgtatggaaa attaatgttt ttatgatgag ggtatgagga caggtttaaa ggtaaaacca 52921 gccctcatca tcatcttcat tatggttttt atccatgctt atttttgtcc ggttgcttcc 52981 gcctaaagat atgctgtaaa gcttcccgct gttaagtttg ctgcaatagt atatgtgttc 53041 gttggccaaa tttataaatt cggaattttc attattgagt tttgttttat cagtgccttc 53101 tgtcctgatt ctgtagatac tgccgccgtc gcttttgttg cagtagtata tccagccgtt 53161 tgacacgttt atattgtagg atatatcatc attcagcttg tttttggaac gaccgtcaat 53221 acttgctctg tacagcttga atccgtcact tttattgcag tagaaaatat aatcaccgta 53281 aacattgatg taactggctt cgtcgtttac gattcttgtt cttcctttac cgagagtatt 53341 tattttgtat atttttcctc cgtcgctttt gttgctgtag tacagccaat catccttcaa 53401 aaagagactc tgggtgaaat cattattcag cttggtcctt tcggtaccgt cggtttttat 53461 tttgtaaagt ttgtatccgt cactttcgtt tatatagtaa atccactctc cgcaaactgt 53521 tatgtcccag gaacggtcag tgttgagtct ggtcttaccg tttccttcca aatcaattct 53581 gaatatattg tcatcattat tcgggtcggt gtaataaatc cagtttccgc agacattaag 53641 aaaccacgat tcgtcattgt ttatcctttg aaggtcgctt ccgtcaagtt tcactttgta 53701 aatattaaag tcacagccgg cattggagaa ataaagccag gaaccctgcg tgcacaccag 53761 tccgccgttt aatatgttgc cggaatggtt tcccgtaaga ttataaacca tttctcttct 53821 taacaaactt ccgaatatgc tgactgtcct gtccagtgtt tttttcggcg cttgtggcgg 53881 ttttggaact tccagcagca cggtatccat acactcatca tctgtatttt tttcgttctg 53941 gtttgcaatg tcagactgcg gcagaattac agtatcaatc actttttcag tatcgtcagc 54001 tttttcagcc tcatcggcag cggccggcgg aacgacccag tatgaacgtt cttcactgct 54061 catttccgac aaaatctcat aaagcgcctt ttttgcctct gtggctgaag catatctttc 54121 gtctggattg taagcacata ttttcaatat aaactgcgag agcttttctc cggcaagcat 54181 cgggggagtg attgcctctc cggaaagcct cttgtccaaa gctgtttcac tgtctttata 54241 tttcaactcc tggggatagg gaggcataaa cggaaatctt ccgtggttta aaagtttata 54301 catcacaata cctagggaat acaggtcgga tcttgaatca tagggctttc ctctgtagac 54361 ttccggtgcc atatagaggg gagtgccccg tatggaggaa gccagcgaga gccgggtcag 54421 ctcttttgca ataccgaaat caccgagctt gaatttgccg tctgatgtga caaatatatt 54481 ttcatccttt atatctctgt gaattattct tttttgctca cagatttcca aagcagaaca 54541 aatatccaaa gcaaggttta ctacccctac ccgggtaagg ccgtttttca atatgtattt 54601 attaagtgtt gtaagatact ccatccgtat gagtatgtcc cagccaaaac gattactgct 54661 tttttgcacc aggtggtctt cgtagcttac tatatttgtg tttccgcgca aggtgtacat 54721 catatgtatt tcgttgacta tatttttaac agcgctttca aaatattgtt ccagagaatt 54781 tttatcgtta ccgatggtag caagagcttc gcggtgctgt tcctgagtgg gaatgcttat 54841 gaattttaaa gcagactggt atttaaagcc ccactcttct ttataaatct tatacacttt 54901 accatagctt ccttcgccga taaaggattc tacaaaccat gctccccaca aaggttcgta 54961 tttttttata tagtcatcag aagaaacgag catttcagaa cctccaaggc aatttatctt 55021 atagtgcttc tataaaatta tagcaccaaa tccggtatac agacaatgaa agatgtaatt 55081 ataatattat aaattgtaat tatgatattg caaatttatg ataagatgtc ttcaatttta 55141 acaacaatgc aggttatatt gtcaaatcct ccgttttcca gtgcctcgtt tataagcttt 55201 gatgcagctt ttgaaggtgt gttttcagtg tttataacat cttttatgcg ctcattttca 55261 accatgttcg taagaccgtc ggtgcaaaga agaaatacat ctcctttttt tacaaaaaag 55321 ctttccgata tgtctgcctc aataattcct tctttagtag gtatgcccag aaacttgtaa 55381 agcatgtttt tacttgcgct ttttgatgct tcttcgggac ttaaaatgcc caatcttaca 55441 agtctttccg cttccgtgtg gtctttggtg agttgaacaa tttcaccgtc tgtcacatga 55501 tatatacggc tgtctcccag gttgaacgtt tgtgcccggt caccgcatat cagaagagcg 55561 gcaaaggttg ttcccattct tgcaccgtat tgaacactca tattatatat cagattattg 55621 gtatttttaa tataagaatt aatattgact gcgcaactgt taatattgcc gttgttattg 55681 tttttaatga gattgtgggc tttttttaat tccctcatgg cagtaagaga ggcttcatct 55741 ccacggattt ctccgcccag gccgtcactt accgcaaaca gaaaaaagga atcagcttcg 55801 tttatatcaa aaagaattgt tttttccgtc atggacggag aaaaaaatat gccgttaaga 55861 taaaaattgt cttcattggc gctgcgcaca taaccgatat gagtcgcggc tgtagcgcga 55921 agaattatat ttttttcact atacatggct tatcctttca tcttaaattt gtttattata 55981 ttcttgccgg tattttaagt tacatagtat ttttatttag tattattatc aattgatata 56041 attgtgatat tgaatacagc aggattgcgg atttatgaca attatagaat tgttagaata 56101 gaaccgtccc atacaccggc gtcttccagt gtttcgtcat ccctgagaac ccgtcccaag 56161 ggctcggcat acagatgaaa cttcgaggtg acgctggtta aatcatcgtc aaggcgaagg 56221 gcataggcta tcaaggatga cagatgcttt gccggtatat cggtggggag ttctaaatca 56281 cgagtgtctt ttttattttt gcacttgacg gtaacaatta cactgttcat aactttacat 56341 cctcacttta aaaaaagcta tgcaattttt acatagcctt tttataattt aatttgatat 56401 caaaataaac ggaggcaaaa acgatggggc tcaaaagccc cttgttttcg ttttatgtat 56461 aaatgtaatt atatatgaat tttatgaccc actgcgaagt ttagcagcta catccttgtc 56521 agcctgttca agagcatttg caacagatgt gagggacctt tcaaggtctg acagacattg 56581 attcagcttg gtttcaagtt cttttctcag tgccataaac tgttctacat aagcttcagc 56641 agctttacct tcccaaatac ttttcaggct gtctatttct ctttgaatac tgttaagaaa 56701 attggtagtt tcactagtct ttttacctat tttcacagca gcgcttcgca cttgctcagg 56761 tgtaatacga ataacacttg ccattttcat atcccccttt aaaaagcatt ttggcataaa 56821 tttcgcctat atgaagtctg taccaaataa caataatatt atctcagaaa aacaaccaaa 56881 aatcaagaga aaattttact tttcataatt tgaattttaa ttattcgaca gattgattgt 56941 tttttctgta acttttatta atctgtgtta tccatgcttt taagatattg ttttccagca 57001 aggcggtttt taccctgcag aaacgaccgc ggtttataag ataaccgtca ccgggcttta 57061 tcgctttttc ggttgttcca tagggaagtc ttacggaaaa tacctgctgg tccgatatgc 57121 ttcccagtag caaacctgtt tgcatgtcct tcatagcctt tgcaaaattg tcccagctgg 57181 aacctatatc ttcggtgtaa gatgccatga taatacttat gccgagatta cgctcctttt 57241 ttaccaggcg ttcaaacaag tccgtgacga tagagtcggc atactgggaa aagtcattta 57301 agtcgtcaat aagaataaga cttaaccggc gatttaaaac aaattccttt tcattaatca 57361 atcctccgga tcgaattctt tcttcgttaa gttcagcttt tctgttatca atttcttgtt 57421 gaagggcttc tgcaaattca cttatgttgt gcccgtcatt tgtatagttt tttgtatggg 57481 gaagctggct taacgcataa agccccagag agcttgagtc aaaaatgtgt atgtccagct 57541 tttccggaga aaatttaagg gcaagggtga cggccagcgc ctgaagaaat gttgtcttac 57601 cgctttgaat atctccggat accaaaaaat gaggagtttc cagaagatct atgaaacatg 57661 gttccatttc attttcttcg attcccagag gtatgcacaa aggcttacgg gcaatagtct 57721 tttttacatc gtcccgtgta ataagatcct tgtaatatac aatttccggc atgacgggaa 57781 taggcttggc tttaggtcct gtccagcttt gggatattgc accgatggtt gatttaattt 57841 taattgttcg ttcaatttct gattctcctt ctgccggcaa ggcagtctga aattcaaggg 57901 gaggattgcc ttttacaaga ccgcgtccgt ttacaggact tggttccagt ccattggttc 57961 ttcccacaat aagtgcataa tcccctttgt cggccatctg gagtgccaca gccagcttga 58021 agttggaact tagtttatag cttatggacg atgtgctgct gttggttatt actatatgca 58081 atccaagatt gccgccttcc ctcgaaatct gaatcagata atcctcatat tctgagtaca 58141 tttcgctgaa ggcggagtaa ttgtcaatga caattacaat tgcaggaagc gtttctccgc 58201 aggaatccct gtaagctgtg aggctgctta ctcctttgtc ggagaagagg tcttttcggg 58261 tatccatttc ttttatgagg aatttgaaaa gtttgcttag tttttcttcc tcgtcgacca 58321 ttaccgttcc tccgacatgg ggaagtccgg agaatatacc cagagttctt acgccaaagt 58381 caaggatgta aatgtttaca tcggaaggag agtagtttaa cgccagcgac ataatgagtg 58441 tctgcaaaaa tgtggttttg ccgtatcccg gtgagccgta tacgattaaa tgcccttctt 58501 ttccaaggtc aactgtcaaa ggaacctggc gctgattttc cgggtcatcc aaaagtccga 58561 cgaccggatt taaccatgaa tccgcctttg tccatttttc accgtcccag catcctttca 58621 catcggcaag gagactttca aggtaaagct tttccggaag aggcggaagc catgggcctt 58681 taagacgaac aatattttct ttttgcgcca cgtttgctat atgggaaacg gcagcctgaa 58741 gctgggtaaa ctcggctttt cttatttgtg atgcggatct tgtataaagt tggtggcgtt 58801 taccgtttat ggccacttct gaaatttcat tgtgagtggt aatttcctca ctggcatcgg 58861 gagtataacc tgctccgctc catgcggact ggaaaagctc aaaaatttca tcgtttccaa 58921 cctggatgta ggctcttccg ggttgtttga tatttgcggc atccggacgt ttgattacat 58981 cctggctgtc ctgaggtccc tgaactttaa gacagatacg gaagcgggcg ttactccata 59041 tctggtcatc aactaccccg gccggctttt gtgttgcgag aataaggtgc actccaaggc 59101 ttcggccgac tcttgcggta cttaccaatt ccctcatgaa atccggctgt tcacttttta 59161 actcggcaaa ctcatccgca attatcacaa gatggggaag aggttctttg gctttttggc 59221 tgtgataaag cttttgatag ctgtctatat gatttactcc gtattgggca aaaattgtct 59281 gtcttctttt aagctcgctc ttaatggata cgagggcacg ggttgtctgg tttcctccaa 59341 ggttggttat tgttccgacc aaatggggca aatcaaggaa agcgtttgcc atgcctcctc 59401 ctttatagtc tataagcaca aaaactacgt catgaggatg aaagtttatt gcaagagaga 59461 ttataaatga ctgtaaaagc tcacttttac cggaacctgt ggtacctgcc accaaaccat 59521 gaggaccctg gccacgttcg tgaaggtcaa gagtaagtat ttcattgcct gtgcgtatgc 59581 caagaggtgc cgccagtgtc cggaaagatt tgttgttttt ccagcgttcc agtacgttta 59641 attcttcaac agttctgacg gaatacatct gcaaaagagt tattgatgaa ggcagactta 59701 cggaagtcaa caattccttt atgcgtattg gtgccattct tcttgcaaaa tgctcggcat 59761 cttttatgga cacaatatcc ggcaaaaaag gcatggggga ggagccttgg tttctttgca 59821 ccatatgtcc ggattttgga gccagctcaa tgatagcctg gcaatctttc ggaagatatt 59881 caattctgtc aaaaagataa atggttgata tacccaaggc ttgattgtta tgagccaaat 59941 aattcataat cggctcatct tcaatcaaac gaatatcggc cagaataaat acataatgag 60001 gcaaatttac cggagttggc ggtatattat ctttatcttt gccggtgcgt tgctcccgtt 60061 cttttattac gtcgtataaa tggctgaaca gctgatgtgt catgtccttg tcatttgcca 60121 gaaaacgaat ttgccgattt tcattccata catggggcag ccagcgaatc cattcccatt 60181 cgtcggcttc ctcttttgga taaaccagca cgatttttac ctcttcatag gagtgaaaag 60241 ttgccagttg tataatcaaa gctctgacgt ttttcagaac ttcgcttctt gatcctatta 60301 ttccggccgt gcctgaatga aacaaaggga cgcaaacagg tatgtccgat acctggctaa 60361 attcatcgta aattttttga ggttctgaca tcaaaggatc gctgtcgatg ctcagcagct 60421 gactttgaac attaatctta attgccaggg gcgtggttcc tatacctatg cgcgccgaca 60481 gaaagtcttt aaactgggga gttctttccc aaagtcttct gtctatggtt tcaacacgtc 60541 tgatacattc cgccgggtca ggattcatga taagcatacc ttttttttgc tgttcccggg 60601 ctatttcaag ttctttgcgt attgaatgga tgatttctcc gtattttttg tttcgcagct 60661 caatatcatc tttgaacttt ttattttgag atatatattg agatattgat acaattaccg 60721 atacaaaggt cattgaaacc gaaagcagca tatagagcga tttgcccaca attgctgtaa 60781 ttattgttat taaggacatt actatcgggg gcagcaaaat acttatccat gatgcggtag 60841 gtttggatgc cagcgccggc ggattgggga ttgttttttc accctcgggc atttcaggta 60901 taagtcttgg agaacgctgt atataggggt aaggcggttt ggtttgtttt aaggctgctt 60961 taagcccgtt gacatatact ctgtccccta tgtggtatac tgaaataaat gaaccttcaa 61021 aaacaatttt atatccgcaa atatatatta cgtcaccttg gcttaagacg ctgtcataaa 61081 cctttttacc gtttagaaag gtgccgttta aactctcaag atccgcgata tgatattttc 61141 cgtcaatgga tttatatatc ttggcatgct cacctgaaac caatttgtca gaataaacta 61201 tgttgcagga ttcacttttt ccgatggtga tttcggaaac accccgtatt tcaaagtttt 61261 ccacaacatt atcataagga tcttctggtt ttacaattat ggcggctctg ctcatggttt 61321 ccggtgaatt tccaataata taagtatcat agggaacgag cattttcctg cttattgtgc 61381 ttccatcgta gaaaatgccc gatttactgt gattgtagat ataccactgg ttatcttctt 61441 ttttaaggga gcagtgattt tcatcaatac aagatgagtc aatcactatg tcatttgtac 61501 cggaacgccc gatggatatt atgtttttat taaaagcatc aatttcaaca atcttaaaaa 61561 aattatcaaa atatatatgc agaagatatt tattactcat gctgattacc tcacaataaa 61621 aatactttta atataattaa cagatttatg aagaaattta caaattgatt cttgtaaaag 61681 aataataaca aaatttgaaa taattcatta ttagcttgaa gtaattcgtt atttatataa 61741 aaaattaatc atataattat agaaattaat agaaattaaa ggtatcacag attttttaaa 61801 tcaattcaat cagttctatt ttttatatct ataaatatgt cactgatatc ttcttcattt 61861 gcttcttccc cggatttgcc gccggaggac tcaattgagt ctttttcgga attctgagag 61921 gaatcaataa actctcttag ttcaagcagc tcatcaatag cactgtcgga ttcttccgcc 61981 tcttttgaag tactttcggt attgttttcc gtatcctgtg ctttttcgtc ttttaattcc 62041 gaaattctaa tttcatcaaa caaattcata atattgccgt cggccggcat ttcagtttca 62101 tccggggcag gagttttttg attgccagat gtatctttct ctggcatatc tatttcttta 62161 atatcatcaa agagtcccaa caagtcttcc tccgaaattt cttctttttc ggcgttggtt 62221 tgcaaattgg attccacttc aaattcaggt gcttcaaact cgttctgcat atcctcttcg 62281 attaagaaat caggtacttc caggtccgcg gacagcatgg cagcatcgtc caaagccgtt 62341 ttatccaaga cttccggttg ttttaattct actgtgaaac tgtcttctaa agcgaggctg 62401 ccgtttataa atatttgcag tttccattcg cccgcaattg tatcatcatt tatattgatc 62461 tgaaataaag cttcattttt cctgttttca tttttttcgc cgtcgtttag gacactttcc 62521 tgaatctcat ggatttcgtt attgggagca taccatattg cgtttaccgt atgcaagccc 62581 gttatgtcgg aaaaaccgat tttcagcata atacttgagt gtttgtcctt atagcatttt 62641 ctttcaccgt tttcacagta tgaaagttct ttgtcaacgc tcaaaaagct gtaactttca 62701 atattgagcg aagcgggttt cgtattgata atcctcttgt tgctttcatc aattatgata 62761 aaagacgcag tgccgccctt gtcatcatag gtgtaaatca gggcgtttgg gtcattaaaa 62821 agtatgctgt catttattaa aaatttgtat ctatatttgc cgggagacag ttcgatttcc 62881 gtcatccatg taccgtcatc atgccttttc aaaatatttt tgccgccgtc ccagttattg 62941 aaatctccta taacagatat acttttaata tcaagattgt cgcaacaata ataaaacgga 63001 tatttcataa aaattcctaa cccctttata agtggaatat atagatacta tagtaacaat 63061 aaaatcttac cataaaattt accattatac cagatatttt atagcaatgt acttttatat 63121 tcataacttt ttataccttg aaagccatat catgtcaaga gcattgtaaa attattggcc 63181 gttatataaa attataaata gaggggtata tgatgggggg agaaatatgc caaaaaaagt 63241 attatgcgtt gtaatgattt ttgtgctgtt tatgagtttt actataagta cagcggctta 63301 caacgcggaa ataaacggtg aagttattgt gtggaacccg ggaataaaag gaggaatccc 63361 tacaaagcct gttgtggcca atgttaagga ttttggagca aagggtgatg gtctgaccga 63421 tgattcaaat gcttttaaaa aagccgttga atctgtgaaa gacggaggag ccgttctgat 63481 tccctcggga gaatatctta taaaatccaa aattacattg gacaagcctg ttgttttaag 63541 aggggaagga cccggaaaaa ccatcctttt gatagatcac tcatccgacg cctttgaggt 63601 cataacttac aaaaggggaa actgggtaag tcttgtcgga ggatataccc gcggctcgac 63661 ggaactggtg gtatccgatc cgacaggctt tgaagccggc aaatatgtgg aaatacagca 63721 ggataacgac cctgacgtaa tgtatacttt gccggaatgg aaccaagggt gggcggcagg 63781 cagcgtagga cagataacaa aggtggtttc gatctggggc aataaaataa ccattgaaga 63841 gcctctcaga atcacataca gatcggaatt aaatcctgta atcagaactc aaggatttgc 63901 ggaatatatc gggtttgaag attttacggt gaagcgtatt gataccagcg acacaaatat 63961 gtttttcttt aagaatgcgg ccaactgctg gataaaaaat atccacagca ttaagcctgc 64021 aaaagcccat gtcagtgtca ccacaggata caggattgaa gttagggaca gctttttcga 64081 cgatgcgaca aattggggcg gaggcgggca cggatatggt gtggaacttg gatttcatgt 64141 atcggactgc ctgattgaga acaacatttt caagcatttg agacattcga tgatggtgca 64201 ccttggcgcc aatggaaatg tttttggcta caattattca acacagccct atcagagtga 64261 aggaggcaac tggacaccgg ccgatatttc agtgcatgga cactatgcct attccaattt 64321 gtttgaagga aatatagtgc aggaaataac tgtttccgat tattggggac cttccggtcc 64381 gtacaacaca ttccttagaa acagaataga gtcagaaagt gtatgccttg aggattcatc 64441 aaactatcag aactttatcg gcaatgaaat tgtaaacggc aatatccttt gggataccga 64501 caatagatat ccgcataaaa tagatccttc cacgctgttt ttacatggca atctcataaa 64561 tggttcaatt cagtggaatc aacaaactca ggaccgtaca ataccaaact cttattatct 64621 tgactcaaaa ccggctttct ttggaggtat taactggccg tcaacgggaa gtgaccgaac 64681 agatggcacc atccctgcaa aagaaagata ttatggaaat acaattccgc ctgcttcacc 64741 gacacccgac aagcccgtta aatatggtga cttaaacggc gataacaatg tcaactcaac 64801 ggatttgaca ctgctgaaga gatacctgac aagggtcatt aatgatttcc ctcatccgga 64861 cggcagtgta aatgctgacg taaacggaga cggaaaaata aactccactg attattcagc 64921 aatgataagg tatattttga gaataattga taagtttcct gccgaaaaga gttaagaaca 64981 aaaaggcata aaaaatattc atctttcgaa ctaatatttc gaacgagata ctccaagtgc 65041 ttttacactt ggatgtggaa cgtttatata ttctactcat ttttttacct tttccacggt 65101 aaggaatatg tctgaattta taaattcgga tatattcctt attttgaata attatatgtg 65161 ccaatgtcca tattattatt aactgttatt gagtttatcc aatattgacc ttggtatcat 65221 taaaatgtgg aggtaataaa atgggtgaaa gagaaatttt tgaacaaatc aacgatgtgc 65281 tgagagaaaa cggatacaac acaagaatta acggacttat ggaccttacg cattttttaa 65341 atgaaaaaag ggatacggac agtttggtgt atgacaaagt cagggaattg tatgctcaat 65401 ttatgatggg tatcggtatg tggtgatttt tcaatatcaa tggcaaatat ttatgcaaaa 65461 acggcttcaa gattaaatga agccgttttc gtgttggagt ttgatatatc aattgctgct 65521 ttattgccac ttattataaa aacagggatt ttacctgggc aatatcactt tggtctgcca 65581 tttgagctgc atgataatat cccttttgtt ctgctaattt gtagaggtca tactgaaaag 65641 tttcgcagct gtttcttatt tgctgcaaag tttgtctcag ctgtggattg gaagactgtg 65701 caatagcgtt tgcataacct gtaagactgc tgtttatttg tgacaacacg tcatttacca 65761 tttctttatc ctgcattatt gttttacctc ctttagttta agaatgacat taattgctgc 65821 tttgtgtttc ttgcatcctg tgcggatttt tggaacattt gttttacctg tgggtctgta 65881 gcctgctgtg cgtatgcttc cagttttttc gctgaagttt catgagaata gataaggtgt 65941 cttaagtttt caagttctaa ctggttgatt tgtggcatat aaaacactcc tctcatttat 66001 atttcactat tagtttcttt taaatcacat aaaatattca aaaaaatata caattaaact 66061 aattttattt gtcctgcttg ttaactgcca tagtatttat tacatactat aagaagtttt 66121 attaagggca cattaaatat tgaaatttgt tttaaaagaa gcaaaagtcg aaggagatga 66181 atcagaagga gatgaattaa gatggaaaat agcagagtat ccacctttaa ggttgctgcg 66241 acatatatag gaactgtggt gggggcggga tttgcatcgg gacaggaaat gcttcagttt 66301 tttgcggttt ttggtttgaa gggtttttgg ggattaattg ttgttacggc tttgtttatt 66361 gtatttggct atattgttat ggaagtcgga agaaatcttc agtcagaatc ccaccttcag 66421 ataatcaaac attccggcgg aaagttttta ggcccgttaa tggactggtt aataactttt 66481 ttcctgtttg gtgcccttac tgcgatgatt gcgggttccg gtgctttggt aaaacagcag 66541 tttggaataa atcctttttg gggaaatttg tttatggccg cttttacggc attgaccgtg 66601 cttacgggaa tcaatggggt aataaactct atcagtgttg tggttccttt tttggttact 66661 tcagcggtgg gtatcagcct ggcttcaatt ttgttaatgc cgctgcggac aaatccttat 66721 gaacttgttg cggcagccga gtctgtgtca cgaaacggat taattggcaa ctggctgtgg 66781 gcggccgttc tttacgtttc atacaactta gtgctggcca tttccgtatt ggggcctttg 66841 ggagtgcagg caaaaaacaa aaacgcgatt agaaacgggg caatacttgg aggaattggg 66901 cttggggtct cggcaacagc aatttatttt gccatggaaa gaaattttga aattgtccgc 66961 gacatggaaa tacccatgat ttatcttgcg ggcagcctgt cttatatatt gcagattgta 67021 tatgcattgg tgcttatcgg tgaaatatat actacggctg ttggaagctt gtacggattt 67081 tcggccagaa tcaccgacat aaatgaaggt aaagcaaagt tttatataat cggagcgacc 67141 cttttggcgc tggccgcaag tcaactggga ttttcaaata tggtaaaata cctttatccc 67201 gttgtgggtt atggaggagt tgtacttctt gcatgccttg ccgtcacaag atttaagctt 67261 gcaaagagag cttagaggaa gaaaaacaaa gtcaacttat ttgtattgtt gatttttttt 67321 cttataatat ataattatta tactattgca attgtgcggt gaatatttat ggagaaatac 67381 acaagactta agttttttga gcatattccg gctgttccgg ataacggaat gatacttacg 67441 aggctgggct acagaaaaac tacaacaata cttgatgatg attataaaaa aacccttatg 67501 gaaaatataa acaagggtct gatgctgtgc aacacaaagg gggtgtttgg aacattcaag 67561 atagaaaaaa gggatgaaga atccgttgag cttgacaatg gtgtggtttt aaagagcaaa 67621 agcctgtcaa aacttctttc aaacagtatg gatgttgttt taatggcatc tacggtggga 67681 aaggaaattg tggacaggat agttgatgaa ataaataaca acaatgcctc tttcggagtt 67741 gtcctggatg ctgtggcttc cgaaacggca gatgccgccc ttgactggat ggttgatttt 67801 attaacaaaa tgataagaag agaagggaag aaacttacca aaatgagata cagtcccggt 67861 tatggagacc tccctttgtc aaatcagaaa ttgatttatg atgttttaaa tttagaaagg 67921 ctgggaatca gcattactga aaggtttatg cttgtgcccg aaaaatcggt cattgctata 67981 gcaggtgtgg aaggggttgg ttgtaatgaa taagaaagat tttttggatt ttctaaatca 68041 aaatatactg attcttgacg gtgctacagg taccgagctt caaaaaagag ggatgcccgg 68101 cggggtatgc cctgagatgt gggtaattga aaatccggat gtgattatgg atatacaaaa 68161 agattacata aatgctgggt caaatgctgt atatacctgt acctttggag gcaatagaat 68221 aaagctttcc gagtttggat tgggtgacaa ggtggttgaa ataaacaaaa aactggcaca 68281 gctttcaaga aaggccgcag gagaaaaggg attggttgcg ggggatcttg cacctaccgg 68341 aagattcgta agaccctttg gggacatgcc ctttgaagag gcggtggatg tttacaagga 68401 acaggtaaag ggccttttgg aaggcggtgt ggactttttt gtaatagaaa ccatgatgga 68461 catacaggaa gcaagagcgg ctctgctggc cgtaaaagaa agctgtgacc ttcctgtgtg 68521 cgtcagcatg acctttgacg aaagcggaag aactcttacg ggaaccgatt cggtgtcggc 68581 tctgattatt ctgcaaagcc ttggagcgga tgttgtagga tgcaactgtt ccacaggacc 68641 gcaagacatg ataaaaataa tcagagaaat gaaaccctat gcaaaagtgc ctctgcttgc 68701 aaagccaaac gcaggacttc ccaaattgat tgacggaaaa acccggtttg atatggaacc 68761 tgaagaattc ggaagttaca taaaagagtt tgtggaagcg ggagtaaatc ttttgggagg 68821 ctgctgcggt acatctcctg tgtacattga gcagattcga aaaaatattg agggattaaa 68881 acccatacct ccacagccaa aagaaatttg tgccgttgct tccgccagaa aaacggtttt 68941 cgttgatgcc aatgaacccg ttgtggtggt gggagagagg attaatccaa cagggaaaaa 69001 gaaactgcag gaggaattgc gtcagggcat gacatccctg gtaaggcaat tcgcagtaga 69061 acaggtggaa aaaggtgcgg acatactgga cgttaatgtg ggcatgccag gaatagatga 69121 aaaggagaca atggtaaaag tagtagaact tttgtcttcc atcactgacg ctccgctttg 69181 tctggattct tcttctccgg aggttcttga ggctgctctt aggatttatc ccggccgggc 69241 ccttataaat tccatttcgg cggaaaaggt aaaaatagag aagcttcttc cgattgctgc 69301 aaaatacgga gcggcgttta tacttcttcc attgggtgat gcaggagtgc ccaagagtgc 69361 cggagaaagg tgtaaaatag ttgaagaagt ttttaatgaa gcgtcaaaat ggggatatac 69421 aaagaaagat gtcatagtgg acggacttgt tatgactgtc tcggccgacc aggaggcggc 69481 tgttgaaaca ttaaaggtca tagaatggtg tacccaaagt tttggctgcg gaacaatagt 69541 gggactttcg aacgtgtctt tcggaatgcc tgagagagct tggataaact cggcttttct 69601 cgctatggca atcggatacg gacttaccat ggccatatta aatccgtcca gcgatactct 69661 tatgagcata aagatggctt cggatgtatt gaaggtcaag gataggaaca gtaaaaaata 69721 tattgagcat tttgcggctt taaagagtga caagccccag gttgttgaaa aaaaggatac 69781 ggcaagccct gttgaaaaag tgtatgatgc cgtggtaaag ggtgacaggg agaatattcg 69841 aaaatatatt gatgatgcgt taaaagacgg aacagagcct tcgataattg ttgataaata 69901 tcttattccc gccataactc atgtgggcga cctttacgac agaaaagagt attttttgcc 69961 tcagcttata caaagtgcgg agacgatgaa agaagccttc ggcattttag aacctcttct 70021 taagaaagaa ccagtggacg aaaaaggtaa caaggtaaaa gtgatacttg ccaccgtaaa 70081 aggagatatc cacgacatcg gaaaaaatat agttggattg atgcttagaa actatggatt 70141 tgaagtatac gatcttggaa aggatgtaag cgccgaagaa atagtgaaaa aagcaaaaga 70201 gacaaatgcg ccgattatag gtctttccgc tcttatgaca acaacaatgc tcgaaatgag 70261 ggaagttgta agcttagtca gacaagaggg gcttaacgct aaaataatga ttggcggagc 70321 ggtggtaaat gctgattatg caaaagaaat cggtgcagac ggatattccg aggatgctta 70381 cggtgcggtg aaacttgcgt caaaacttgc aggaatttaa aaatataata aaaattgata 70441 tggaaaacaa attaattatt aaaaattaaa aacatattgt tattaaaaaa ttataaaaaa 70501 tatgggttgg gaatataaga atcctattga cactatatat ggtgtatggt ataattaacc 70561 acaacaagat attgataaag atatgggtgc ctgggaagtt gccgtctcag gttaaaaggg 70621 aagcaggtga gaatcctgca cggtcccgcc gctgtattga ggagatgttt caaatttgtg 70681 ccactgaatt aattgcagaa ttaatttggg aaggcttgaa acgtcgatga ttctaagtca 70741 gaaaacctgc ctgtatctga gaaacaccgt tgctctacga aggataggga ggtgttgaga 70801 gtttctgttt ttccaaagca gtctcaaatt tgtaaaagag actgttcagt ttgccatgtc 70861 catataaata tcatcataca gatcatctta ttttctcatg aacttgagct tttcttggga 70921 gtgttaattt gtccggcgta cacaaggata cgtacacaag gatatttttg tgtctgcgaa 70981 aaaaatcaga ggggagatgt attaatggtt acgaaaattt caaaaaggga tggaagaatt 71041 gaaaagtacc agcctgagaa aataacctgg gcaatattta aagctgcaac tgcctgcgga 71101 ggaagtgatt ttggccgtgc tgaagaactt tgccgccagg taaatgaaat actcaacaaa 71161 cagtttaaag acaggatacc tggagtagaa gatatccagg acattgttga aaaggttttg 71221 attgagaacg gtcatgccaa aactgcaaag gcgtacatat tgtaccgtga gaaaaggaaa 71281 agcgcccggg atttgaatgc cttggtggga gccactatta acatgttttc agactacctg 71341 ggggacaggg actggcatat taaggagaat gccaatactc aaaaaagtgt aaacggcctg 71401 aacaattatg tgagagaggt ttttacaaaa aaatactggc tttatgaaat ttatcccgct 71461 gaagtaagag aagcgcatga aaacggagac tgccacatac atgacctggg tttcttcggt 71521 ccttactgcg caggttggga tttacgccag ttgcttttag acggattcgg cggtgttgaa 71581 ggtaaagtgg aaagcaggcc ggcaaagcat ttgagatcat ttttgggaca aattgtaaat 71641 tccactttca caactcaggg agaaacagcc ggagctcagg catggtccag ttttgataca 71701 tattgtgcgc cgtttatacg ttatgacaac atgacgtatg aacaggtaaa acagtgcctt 71761 caggagttcg tttttaacat aaatgtaccc acaagagtag gatttcagtg tcctttttca 71821 aatcttacat ttgacataaa ggtaccaaac actttgaaag atgagccggt tattatcggc 71881 ggaaaatata tggatgcaac ttacaaagaa ttccaaaagg aaatggatat gtttaatacg 71941 gccttttgtg atgtaatgtt ggaaggcgat gcgaagggaa gagtgtttac ctttccgata 72001 cctactatta atatcacaaa ggattttgac tgggataacc cggtagtgga taaatttatg 72061 aaaataactt gcaaatacgg cataccgtat tttgcaaatt atataaactc ggatttgtcg 72121 ccggaagatg ccgtatctat gtgctgcagg ctgagaattg acactaccga gcttagaaaa 72181 agaggaggag ggctttttgg aagcaaccca ctgaccgggt ccattggagt ttttacaatc 72241 aaccttccaa gaatcggtta tctttcaaaa tctgaaagtg aatttaagga aagactttgg 72301 aaaatcgcga atataggcaa aacatctctg gagatcaaga gaaagataat tgagcagcag 72361 tcggaaaagg gactttatcc gtattcaacc cattacttaa ggcacgttaa gcaaaggaca 72421 ggagaatatt ggttcaatca cttcaatact attggaattg ttggaatgaa tgaagcgctc 72481 aaaaacttta tgggaaaaga tataacgact ccggaaggcc aaaagtttgc cattgatata 72541 atgcattatt tgagggatat tttgttggaa ttccagaacg aaaccggaca tttttacaat 72601 ctggaagcca ctcctgcgga aggaacatct tacaggcttg ccaaaattga caaggaaaga 72661 tatcctgaca taattacagc aggacgtgat atcccatatt atacaaactc aacccagctt 72721 cctgtggatt atacggatga tatttttgag actttggaac ttcaggacga actccagtct 72781 ctctacaccg gaggtacggt tcagcatctt tatcttggcg aaagcattga agatgtcaat 72841 gtgtgcaaga atcttataag aaaggtgttt acaaattaca aaatgcccta tatctcaatt 72901 actccaacct ttagcatctg caaggaccat ggatatataa aaggagagca tttcaaatgt 72961 cctgaatgcg gcaacgatac cgaggtatgg tcaagggtaa ccgggtattt aagaccggtg 73021 gcaaattata atattggtaa aaaggaagag tatttcaaca ggaagaaatt taaactggcg 73081 gagaaagtgt catgagaatt gcagggatac ataaaaactc ctttgtggat ttcccaggaa 73141 aaatagcaat tgttgttttc acaccgggct gcaacatgaa ttgcttttac tgtcacaata 73201 aaacactgat ttccggaggc aacgaggagt ttattgataa tgatgaggtt cttgaactgc 73261 ttgtcaaaag aagaggattt atcgacggcg tggttataag cggaggagag cccacacttc 73321 agaaggatct ggaaggtttt ttggaaaagg tcaaatccct gggatatgcg gtaaagctgg 73381 ataccaacgg gacaaatccc catgtggttg aaaaccttgt ccaaaatggg ctggtggatt 73441 atattgcaat ggacgtgaaa gctccttttg gcaaatataa tgaaatttgc cgcacaaacg 73501 tggatgttga tagcattaaa aagagcattg aaattataaa aagcggcaaa gtagactatg 73561 agttccgcac taccgttgct ccggggcttg aaatggacga tatctttgaa atagcaagag 73621 gtattgaagg ggcaagactg tatgtcctgc agaaatatcg ggatgtgtcg gaaagcgctg 73681 tgaaggactt ccgtaatcct caatttctgc tggatgcggc agtaaggata aaaggaattg 73741 ttcagagagt ggaaacaaga ggagtggcgt tttgcgctta gtttctgtta tcaattactg 73801 ttaaacaaaa gcgatggatg aaatctccat cgcttttata atatataatc ttgtaataat 73861 tattctttaa aataaataaa tataatttct tttatataat tttttataac aaaatctaat 73921 tttgtaacat ttactacaac aattctttgc aacattcttt atagcaatct ttgaattctt 73981 tctcttactt tttcttcgcc cataatctgc tgtatctccc aaaggtccgg tgaactgctg 74041 cggcctacta tggcgattct tataacagtg cttacatcac ccacatgtcc tttgtacatg 74101 tcgggatttt tcttgtagtc ctttggtttt gccgcatatc cgttttctgt ggcaataacc 74161 ttgatttttt caaaccactg tgtttgatca tcgttgtggt cgtaggtttc aaggtatgcc 74221 ttaagtattt ttttggcttc ctcttcgtct acgttgtccg gatatttgtc aactattgca 74281 aagtattcat caaagaaata tttaatgaac tcaaatattt gttcacaata gattaagtct 74341 ttgcgcggtt tttcagaatt tctgcccaca gacaaaagtt ttattaccga atccttatgt 74401 tcttcgagca gattaacaat ctcttttttg tattcctttg cccatttcag caaaaattca 74461 taaatttctt ccgccggaat tttagccaaa acatttttgc ttacatcgtt aagtttgtcc 74521 aagtcaaaca aagcaccgga attactcatt ttattcagag agaaaggaaa atcatttata 74581 tcgctgtccg gattttgaat tctccactct tcaaagttgg agtttaatat tgtcataaga 74641 tactctctta ctgcagcggg gtgatacccc agttgcatgt aatattccaa tcccaattcc 74701 ggatcctttc tttttgaaag ctttctttta actccgttgt ctattttcat caaatgggct 74761 gtatgacagt ataccggcaa atcccatccc agtgtcgtaa acaattcata atggatggga 74821 agggttgaaa gccattcctc acctcttacc acatgggtaa ctctcatcaa atggtcatcc 74881 accacatggg caaaatggta ggttggtata ccgtttgctt ttagaagcac tatgtcctga 74941 aagttaacct gcatggaaag acggcctctt atggcatcat caatttcaaa ggtttcttca 75001 ggattaccca tggatttaaa acgaataacg aagctttcgt tgttttccag atgcttttga 75061 acttcttcca aggtcaaatt tctgtgaaca gcccatttgc cgtagtaacc tgtattaacg 75121 ttttcagcca gttgctgttt tcttatttcc tcaagttctt cttccgagca gaaacaagga 75181 taggctctgc ccatttcaac caaatgtttg gccacggttt gataaatttc agcacgattg 75241 ctctgaaaat acgggccgta attgcctgtt tctccgttga tgcctgctcc ttcgtcaaat 75301 ttgaggttga agaactccaa agaggatata atggtttcca ctgctccttc aactttacgc 75361 ttgtcatcag tatcctctat gcggagaata aacactccgt tgctctgatg agccagacgt 75421 tcatccacga aagccccgta cagattgcca agatggataa aacctgtcgg acttggcgcc 75481 agccgcgtaa cttttgctcc ggggcttaaa tttctggcag gaaatacaac gtcttcgtaa 75541 taggaaaccg atttggttat gtgcgggaaa agcatgtccg ccaacttttt ataatccata 75601 ttgcacctca ttgttatttt ttttatagtt atttatagtc aaaattaaag acggcttttg 75661 ttgttaaaac aaagaaccgt cgtattattc ctttggtgac ccatagggga atcgaacccc 75721 tgtttccacc ttgagagggt ggcgtcttag ccgcttgacc aatgggccgt attgcaatga 75781 atatattatg cactgtacac gcaacatatt atacactcaa cggatttttt tttcaatatt 75841 aaattagaaa aaatttttgg cagtatattt aattaagtaa tgttttttac tttcacgtca 75901 gtttttcggc aaaattttgt taatgttcgc aggttttaaa atttgttgct aaaaggtaaa 75961 tgttacgaag ataaaaaaag tagtggactg ctacatgtat aatctgataa aatatgggag 76021 atagggctaa taaagtttat ttttcttgtt tttcacggtt ttgaagaata tttttgacga 76081 catattatcc ggcttaataa aggagtataa tgtatgacgg atttgtttat gaagataaaa 76141 aatttttcac cttcagtaag atgggaaaca caggctgtct gatttcctgc gttgcaacgg 76201 ccataacgaa tctgaatgtt ccgataactc caaaagaatt aaacgcggct ttgactgaaa 76261 aggacggttt tcttggtgtc gatttaatct ggtataaaat aaacgaggcc ataccggaag 76321 ttgactatag atacagccgt atttttaaca gcaaaaccat agaaaaggat cttgaaagag 76381 gacttttacc cattgtaaat gcccgctacc ataaaaccgg agaactcatt gagtgctgat 76441 tgtgagggca aaagaagggg agtttattat ctgttaccca ctggatgacg gaactgaaac 76501 aagattgctt tcagaccacg ggagggttta tgcttacagg gtaactgaaa gggcagaaag 76561 gtgattttgt tgaaagaaaa aaatgtcttt gtaatcacag gaccatgcgg tgtgggtaaa 76621 tccacggcat ctcgcaggct ggcgcaaact ttggacaaga gttgtcatat aaatgcgaat 76681 ttgatttatg agatggtagt tggcagatat ttgtttccgt ggcaggaagt attaaaatat 76741 atagtcctga tggcagatga gaacactgtc agaatgaggg acggtaaaag acctcctcaa 76801 gaggttatgg gggacagggc tatagaggtt tttaatgaat ttaaagataa aaaaaattga 76861 ctgcaaatat attcttgata cgtcttgcaa gagtattgag gatattgttt tagagattaa 76921 aagggaagag cgctttataa tggaaaaata actctactga aggtttgcag gaggatggta 76981 atatgaatag tgttaagata aatgtaaaat atacaacgaa agactttaag gatttttttc 77041 tgtccacaag atttatgggt ataataggaa aaatgaatat tgcaatatct ttattctttc 77101 ttttggtaat cggtgtgctg gttttaaata caataggtta tataaccatt aaccctgaag 77161 atactgaaac aatatcgttt ttgctttttt cagtcgtttt tctttcggtg ctttttacga 77221 tgataggttt atttccgttt tttgtaagct acttcgttga gaaaagatta ttttttagga 77281 aacaattaca gcagcccttt aattgtatag aagtaacgga agagaagatt actgttttta 77341 attctgaaag tacctttact tttttctgga atgatgtata taaagttgag gagttaaagc 77401 ctgttttttt tgatatatgt gtctttttac aacaaaataa taattccaaa gaggtgtttt 77461 gtttcacagg aacatttggt taatttcaga agaatcctgt atataagcaa attggataaa 77521 cgaaaactaa aacttaaaaa ctatgagttg aaaaagtcgt ctcctgatta tggggaagta 77581 gaatttaaaa cccaacctct cagcgagtat agcgagtata ttgaagaaaa tgcagaaaaa 77641 aatcccgagt tggagcttga tatcatattc gaaaaaaagg atatattaaa aatgagtttc 77701 gcaagaatct tttcagatcc agcaacgatt attattatat cgatcggttt gatacttttt 77761 gtattcggaa ttttatattt tgggtcgtta cttaatcctg ctactgtaat agtggctttt 77821 cttgcatttc ctcagtttat tttcttgcca atagccgtaa gtttcggata caataagtta 77881 tataaaaatg atgataattt aaaaaagtct gttaaataca ttttctacaa agattattat 77941 gtaatcaaga attttgcggg agaaagacga attgattgta taaatattga gaaggttgtt 78001 gagaaagaat cttgttttgt tttgcattta acctctaaat tgttacaaat aatgccaaaa 78061 aaagtttttg aagaaaaaga acgtgagcta aagaaattca gacagctcat gaatgaatat 78121 caaagctgta agtcttcggt gagagtttaa taaggagttc tatccagctt agcggtttta 78181 aaaagctttt ttctgatggt ataaataact aattgtcagg gaggaatacg aaatgccgca 78241 tgttatcgtt aaattatggc ccggaaggac ggaagaacaa aaacaggagc ttgcaaacag 78301 aatcgcaaag gatgtcatag aaacattaaa tgctcctcaa accagcgttt ccgtaagcat 78361 tcaggaagtt ccaagagaaa aatgggttga tgaagtgtat aatcctgata taatggacaa 78421 agaagaaaca ctttatatta agcctggata caaaccggaa aatctttaaa gggagtttgt 78481 aagggaagct ttgaatataa aaagcctaaa ataatatgaa tttctgttta catttcatat 78541 agatttggta tataattaat atagttaatt ttttaacgaa ggcagaagaa ttagaaatgg 78601 agaaagaaaa taggaaggaa aaccgcatag ccgttatagg aattgtaatt cacaaccgtg 78661 aggaaagttc aaggaaagta aacgagatat tgagtgatta cggcaatata attgtcggaa 78721 gaatgggtgt gccgtacaag gaaaaaggca tttctgtaat agcaataatt gttgacggca 78781 caactgatga aataggggct cttacaggca agcttggcaa cataaacgga gtgaaggcaa 78841 aagttgcttt aacaaattaa agcccttaaa ttaaacttga attaaaatga aaatttgata 78901 ttggtttcta agatgcagga attgttaaaa ttctgacatc gaggaacgta tttatggttt 78961 tacctgacgt gacggattgc catttatggt aactacggga atctgagcga agggggaata 79021 gatatggtag ttttgtctat aaactcttcc tgacttatgt aggtcacgaa gagtttttgt 79081 ttttctgatt ccatatagtg gaactggcaa aaggtaaatt tatacaatat gtgccgatac 79141 aaggtttgta aattgaaagt gggggatatt caaatggttg aaaaagttga ttttataaaa 79201 gaagatttga ttttttctct tcttgaaaaa ggtaaaatta ctgacaggaa tgaaataaga 79261 gaaatattgg caaaagccag ggagtgcaag ggcataagcc tgggagaagt tgcaaagctg 79321 ctttacctgg aagacgaaga gctgttggaa gaactctatg atgtggccaa atatataaaa 79381 aacaaaatat acggaaaaag agtggttttg tttgctcctt tatatacaag caatgagtgt 79441 acaaacaact gcctttactg cggtttcagg catgacaaca aagagcttca cagaaagact 79501 ttaagtcttg aagaaatagt ggaagaagca aaagctattg aaagacaggg acataaaaga 79561 ttgctcctta tttgcggaga agatcccaga aagactaatg taaagcattt taccgatgca 79621 atggaggcaa tatataaatc caccgatatc agaagaatca atgtcgaggc cgcgccgatg 79681 acggtggaag attacaggga gctgaagaaa gccggtatag gaacttatgt gatattccag 79741 gagacatatc acagggaaac ctatagaata atgcatcctg tgggcaaaaa agcgaattat 79801 gactggcgta taacggcaat agacagagcc tttgaaggcg gtattgacga tgtgggtgtc 79861 ggagcgctct tcggacttta tgattataga ttcgaagttt taggcctttt gatgcattgt 79921 atgcactttg aagaaaaata tggtgtaggg ccgcacacca tatctgttcc gagacttcgt 79981 cctgccttgg gagctccttt gaaagagatt ccgtacaaag ttaccgacaa ggatttcaag 80041 aaaattgtgg ccatattccg aattgctgtt ccatatacgg gaattattct ttcaacaaga 80101 gaaagagctg aattcaggga tgaactttta agtgttggag tatctcagat aagtgcaggt 80161 tccaaaacca atcccggagg ataccaggag gatgacgacc atgcggatca gtttgaaata 80221 agtgacaaca ggagtttgcc gaaagtaatg gaaacaatat gtcaacaagg ttatattcca 80281 agcttttgca ccgcttgcta cagaagatgt cgtaccgggg agcatttcat ggaatatgca 80341 aaggccgggg atatacatga attctgtcag ccgaatgcca ttctaacttt caaggaaaac 80401 ttaatggatt atgccgatga gcctttgaga aaaatgggtg aggaagtaat acttaaggct 80461 ctggaagaaa ttgaagatga aaaaatgaag actcttacta ttgcaaaact tgaggaaatt 80521 gaaaaaggaa agagagatat ttatttttaa aagctgaaaa atttaagtga tattagaagc 80581 aataaactga atatatatgt atatgaaaaa agaagcaata aactgaatat atatgtatat 80641 gaaaaaagat ttagaaacat aaatacaatt tgttttccgg aatttgtttt cgatacccgg 80701 acattttatt acagaatata gaacagttgg caaactcctt ggatatttat aaaaattgta 80761 aggatggaat aaaatgattt atcttgacaa tgcggcaact tcatatccga agcctgacag 80821 agtttatgat gaaatgcttt tatgtatgaa ggaatactgt gcaaatcccg gaaggtcagg 80881 gcatgaactg gcaataaaaa cgggaagggc ggtgtatgaa acccgggaaa ttgtgtcaag 80941 atttttcaat atcgaaaatc ctatgagggt cgtatttacc aaaaatgcaa cagaagcttt 81001 gaaccttgcc attaacggag tattgaaaga aggggatcat gtaattacta caagcatgga 81061 gcacaactct gttttaagac ctttaaaaac gctggagaga aacaatatta tagagcttac 81121 catagtatgg ggaaattatt tcggtgaaat tgatgtagcg gatatagaaa gaagtataaa 81181 aaagaacaca aaaatgatta tatgttccct ttcctccaac gttaatggta taataatgcc 81241 cgtaaaagaa atagggaaaa taaccaggga aaggggaatt ttatttcttg ttgacgcatc 81301 ccaaggggca ggttctataa agctggatgt ccaggaaata aatgcagatt tgtttgccgt 81361 tccgggccat aaggatttac ttggtcccca gggagtaggt gcactttatg tgaacgaaaa 81421 tgtggaaata acgccgataa tgcagggggg tacaggcagt cgttctgaaa gtttttatca 81481 accggaaata ttccccgata tgctggaaag cggaaccttg aatgctccag gcatagtcgg 81541 tttgggattt gggattaaat ttatagaaag tttcggagtt gacaatatca gaatttacaa 81601 gcatatgctt ataaaaagat tatatgaagg cattgaaaat ttaaacggaa taaagcttta 81661 cagcctgaaa gacatggata aaaactccgg aattatttcc ttcaatttta taggtgtgga 81721 ttctacaaaa gtgagtttta tgcttgacag aatatacggc attgcttcca ggtccggcct 81781 tcactgtgcg cctttggccc atgaaaccat tgggacaaaa gcaaccggta cagtgaggct 81841 aagtgtggga tgttttaata ccattgagga aatagatact acaattgaag cattaagaga 81901 aatttcccag ggattataaa aaactgactt tttattttca tagttcaaac aaaagggaaa 81961 tatagaaaaa taaaatgaat taatttttat atggtggaaa tctaaaaact attatgctat 82021 aattatttat catgtatata tattaaaggt gtattatgta aattgatgag ttttgatgac 82081 tggtattgta ccccatttta ttgacaagat aacaatgtct tattttattt ttaaatatat 82141 gttttatttt taaatatatg gaaagttata aagtgtaata tataaagtta taaagtgtgc 82201 acttttaagg gggatagatg tttaaatgct gctggatttg tttatgaaaa agacttcaat 82261 ggtatgtata gatgtcgggt atcgaaatat aaaagttgtt gaagtcgccg taaagaagaa 82321 taataatatt tttattgaaa attacggtat tgttccgacc ccgcctgatt gcattaagaa 82381 cggtgcaata tatgacgttg acagggtatt gagcgtgatt aaaagcgtta taagagagca 82441 aaacatgaaa gctaaaaatg caaaaattat aatgtccgga acaaacataa taacaagaat 82501 ttacttaatt gacaaagtac agggagaaag cgaagatttc accgtaaaga acagtatgcc 82561 tcaatttctc cccattgata tagataatta cagagttgac tataaaattc ttcagacaat 82621 aaaggaaaaa ggcagtgaaa aatacaaagt ttttgtgacg gcagtaccta aaaacatcct 82681 tcaaagttat gttgacgtgt tgcaaggttt ggatttaaag cctctggctg ttgacatacc 82741 ggcaaatagt actgcaaaat tttttaacag ggaaattctc acaagagata tggatgaata 82801 ttattccaag aggaagtata aaaaagtgga aagtgacact tttgcagtat tggactttgg 82861 atctgagacg acaattgtta attttcttaa agacagagtg cttgaattta acaaagttat 82921 tctttccgga agttccaata ttgacgagca tattgcaagg gaactcaata taagtcttca 82981 ggaagctgaa agacttaaga aaacatatgg aatgactccc cccaacaatc tttcaaaaag 83041 agaacatgta ataacttacg gaaaagtcag caattttatt gaaaggctta cccggcagat 83101 agcaaagtgt tttgaatttt atcttgaaag gtgttatggt actccgattt caaagatttt 83161 tattataggt ggaggttcac agcttagcgg acttaatcaa tatttgtttt caacgttcaa 83221 tgtcccggtt tatcccgtag gacttttgaa tctcaaagga gttgagctta agaaaaatct 83281 tgacaaagat aaactcaatt acctgataaa tgctgtggga atatcccttt aattccttta 83341 atttttagaa aggtgaaaat tgttttttta tttttgtcta cttaattcaa aggtaaaatc 83401 attaagtaaa tgaagtttac agcaaactcc agtttttgtt cactggagtt tttattttta 83461 ttatcatatt ttgtttttgc atcaaattaa acaaattaac atataaataa aataaattaa 83521 ttttttatta gacaaaaatt aaaatttatc gtataataaa ttaaaaaagt taatagaggt 83581 gattttaatg gaaaaggaaa acactatggt taaatcaata ataacgataa ttgttgccat 83641 aatattgctg gttatagtcg ttaaattggt ttcatgggct gtttacaagc ttttacccat 83701 agctatagtt ataattgcgg catacatagt atacaaagtt gtcacatcaa ggaaaaatta 83761 aacatatatt atacccggta ttatccaagt tttccaatac cgggtatata ctttgatttc 83821 caaaatttat aaaacgaatt tgaacgttta aagaatgagc tttatacatt cccaaagaac 83881 atcgcatagc tcctttgatt caaagtcgct tccatagccg gaaagattgt agtctttgct 83941 tcccatttcc acggcaaatt ggccgttgtc agccaacagg taaaaatcgt acaacttgga 84001 cttgtgtttg tctaaaattt caatcatctg agcgatactt aacagaggaa ggcaatcttc 84061 tttcgaaaag gtagttggac ggatatataa actgtcaaag ttttcatttt cggttgaatc 84121 ttcgttaata tcatattcgc tgtcgtaatt gtcgtcgaaa tccgaatcca attcttcaaa 84181 atcaaaatct tctgaagctt cttgtccgga aaaattatca ctattcgtat tgtttaaaaa 84241 cgctaaatca tggagaacaa agcggttgtg atagaccgag acatctccta caacaaattc 84301 gatttgctgg tattcttctg tttccgcatt ggtacatatg ttggcaacgg caagatcata 84361 tttttgggga taccacattt cattcaaatg cattttttga gcatcggtaa gttgtgcaag 84421 atcttctttt gtaatatacc ttttcatttt agaatcaatc cctccgttta ctcaaagctt 84481 gcctgacttt gaggccatac ttgagttttt gcttatcgac ctttataaaa aatttgcagt 84541 attataatat catattttgt ttccaaatta tatatttagt ttttaatttg gttgtctgaa 84601 tattagaata tttatgtaaa agtacaaata aaattagtat tagggaggtg tgaaattata 84661 tgaaatgtcc tgtctgtaaa aacatatttc ttgaaaaaac gagtttgctt gacgagttgt 84721 atgcatattc ctgtaagtcc tgcggcggaa actggatgag atatgaagat tattggaaat 84781 ggcatgaaag caaccctaat ccggcaaaca aaccccttga tataaaaact catttgccgg 84841 tgaatgacat catccaggcc aaaatatgtc cggattgcgg tagaatactc ataaaataca 84901 gagttgacaa caggttggat ttttatgtgg agcattgcgg caattgtaat ggaatatggt 84961 ttgataaaaa cgagtgggat aatattaagc taaacaatct gcacggacag atacaccact 85021 tttttacaaa accttggcaa aaaagaattc gggaggaagc agccagggaa aaccttcaag 85081 acaaatatat aaagaagttt ggacgttggg attatgaaag gttgaaagaa atgagggaat 85141 ggatatacaa acaggaaaaa aagaacgaaa tgctctccta ccttcttgat gaagatccgt 85201 acaaaatata aaagaattgt cgtaatttat tttttggctt tatggtctaa ttttaagtta 85261 atctttttgc aaatttgttt ttgtataatg taaccggcaa atattcctat tgccatgcaa 85321 attaaaggaa gccacaccgg accgaaaagc acaccgttaa tattaaagga tggggaatat 85381 acggtgccaa ccgttcctaa gtatgctgca aacacataag gaagaaaagc cataggcgaa 85441 ttatctcctt ttgcgtattt gtaagcatcc cagattacat aaagatataa tgacggataa 85501 aacatcagcc attgataatt ggcattattg acagcctcag ctatatttcc tgtaaaactg 85561 tatattatga tactgtttaa attggagtaa tgatttatta acagttcgag aatcataaaa 85621 aaaatacctt taactatttg accgttcaga agttgtccaa gacccggaaa agctatactc 85681 cacatcattt tttcaatttt atcatttatt ttcataacta agtatactcc attgtatttt 85741 tataaatttt ctatttaaat aaaataaaaa atttatttgt acaattagta tttatccatg 85801 gtatgatata tatacatatg gattatttta tattttatgg attttacaat ggtcaaatgt 85861 attgattgcc tgaaggaaag cggctaatgt aaattataaa tatagaaact gcttaccaag 85921 gagagaaaac atatgttaaa gaaaaaaaca ataatatctc ttgtactggc agcaataatt 85981 ctggggagta ttattcagcc ttttgaaatt gccaatgctc agtattaccg tgagggaacg 86041 ggaagttata ccgtagtttt gccaccgggt gctaaggtac ctcaggcaga gatttacaag 86101 acatccaatt tacagggggc agttccgacc aacagctggg aaagctcaat tttatggaat 86161 caatattcac ttccgatata tgctcatcct ttgacattta aatttaaagc cgaaggtatt 86221 gaagtaggaa agcctgcatt gggaggctcg ggaatagctt attttggcgc ccataaaaat 86281 gactttaccg ttggacactc atctgtctac acttttcctg atgcaagggc ggataaaata 86341 tccgattttg ccgtcgatgc ggttatggct tcaggttcag gcagtatcaa ggctacattg 86401 atgaagggaa gtccttatgc ttattttgtt tttacaggcg gaaatcccag aattgatttt 86461 tccggtactc ctacagtgtt ttacggggat tccggcagcc aatgccttgg cgttacaata 86521 aacggtgtaa attacgggct ttttgctccg tctggctcaa aatggcaggg aattggaaca 86581 ggtacgataa cttgcatact tccggcggga aaaaactatt tttcaattgc ggttttacct 86641 gacaacacag tttccactct tacatattat aaagattacg cctactgctt tgtgacagat 86701 acaaaagtgg aatggagcta caatgagaca gaaagcactc ttaccaccac ttttacggca 86761 gaagtttccg taaaggaagg gacaaacaaa ggcacaattc ttgcccttta ccctcatcaa 86821 tggcgaaaca atccgcatat tttgcctctt ccatatactt attcgacact gagaggcata 86881 atgaaaacaa ttcaaggtac aagctttaaa actgtatacc gctaccatgg aattttgccc 86941 aatctccctg acaaaggaac ctacgacagg gaagcattga acagatatat caatgaactg 87001 gctttgcagg cagacgctcc tgttgccgtt gacacctatt ggtttggaaa gcatcttggc 87061 aagctttcat gcgcccttcc cattgcggag cagcttggaa atatttctgc aaaagaccgc 87121 tttataagct ttatgaaatc atctttggaa gactggttta ccgcaaaaga aggagaaacg 87181 gcaaaactat tctattacga cagtaactgg ggaactttga taggttaccc ttcaagctac 87241 ggaagtgatg aagagttaaa tgaccatcat tttcattacg gttattttct tcacgccgcg 87301 gcccaaatag cgttaagaga cccgcaatgg gcatcccgtg acaattgggg agcaatggtt 87361 gagctcttaa tcaaggatat tgcaaactgg gacagaaatg acacaaggtt tcctttccta 87421 agaaattttg acccctacga gggccattcc tgggcttcgg gtcatgccgg atttgccgac 87481 ggcaacaatc aagagtcatc atcggaggcc atcaacgcat ggcaggcaat aattttatgg 87541 ggagaagcaa caggaaacaa aacgataaga gaccttggaa tttatcttta taccactgaa 87601 gttgaagctg tctgcaatta ctggtttgat ttgtacaaag acatattttc accttcctat 87661 ggacataatt acgcttccat ggtgtgggga ggcaaatact gccatgaaat ctggtgggac 87721 ggtacaaatt ccgaaaagca tggcataaac tttttgccaa tcacagccgc ttcattgtat 87781 cttggaaaag acccgaatta tataaagcaa aactatgagg agatgttaag agagtgcgga 87841 acgtcacagc ctcccaattg gaaggatata cagtatatgt attatgccct ttatgatcct 87901 gcggcggcta aaaatatgtg gaacgaaagc attgttccgg aagacggaga aagcaaagcc 87961 catacttatc actggatttg caaccttgac agtttggggc ttcctgattt cagtgttact 88021 gcagacacac ccctctactc ggtatttaat aaaaacaaca tcagaaccta tgttgtttac 88081 aatgcttcat cgtctgcaaa aaaggttact ttttccgacg gaaaagtaat gacggtgggg 88141 cctcattcca tggcagtttc aaccggcagt gaaagtgagg ttttggccgg agatttaaac 88201 ggtgacggca aaataaactc cacagacata agccttatga agagatacct tttaaagcaa 88261 attgtagacc tgccggtgga agatgatatt aaagctgcag acataaacaa agacggcaaa 88321 gttaattcaa ccgacatgtc gattctaaaa agagtgatat tgagaaatta tccgctttaa 88381 gttgaagtta caggtgcaat atgagaaaat atataatgaa gtaataaaga taatatcaaa 88441 agcataaaga atattccaaa ttttacttaa acagattagc ttatttgttt tgtgctggtt 88501 tgtaataatg tgcatttgtt ataccaataa acggcatggg aatgctgttt ttaagtatag 88561 cgtcatttat aggggggaag gaaagtggta aaaaagaatg tcggattgag gtttctttca 88621 atcctgattc ttatggcact tctcattgga aatgtccaaa gttttaatgt ggcggcggca 88681 gaaggggtta tagtcaacgg aactcagttt aaagacacat cgggaaatgt gatacatgcc 88741 catgggggag gcatgttaaa gcatggtgac tattattact ggtacggtga ataccgggac 88801 gactccaact tgtttttggg tgtaagttgc tacaggtcaa aagatcttgt aaactgggaa 88861 tacagaggag aagtgctgag ccgaaattcc gctcctgaac tgaatcactg caatattgaa 88921 agaccgaaag tcatgtacaa cgcatcaacc ggtgaatttg tcatgtggat gcactgggag 88981 aacggcataa actacggtca ggcaagagca gctgttgcgt attccaaaac gcccgacggc 89041 aaattcacat acattcgaag ctttcgtccc atgcaggata ccggcgttat ggatcatggc 89101 cttccgggat atatgtcaag ggactgcaat gtatttgtgg acactgacgg caagggatat 89161 tttatatccg cagccaatga gaacatggac ctgcaccttt atgagctgac acctgactat 89221 aaaaatattg catcccttaa ggcaaagctg tttgtcggac agcagaggga agcaccatgc 89281 cttataaaga gaaacggcta ctattacctt attacttccg gttgtacagg ttggaacccg 89341 aatcaggcta aatacgcata ttccaaagat ttggccagtg gctggtccca gctttacaat 89401 cttggtaatt caaccaccta caggtcacag ccgactttta tcattcccgt tcagggaagc 89461 tcgggaacca gttatcttta tatgggtgac cgttgggccg gtgcctgggg aggaaaggtt 89521 aatgactccc aatatgtatg gcttccctta aacttcatat ccgatacaac acttgaactg 89581 ccctattatg actctgtaaa gattgatgct tcttcaggaa taatttccga gtacataccg 89641 gacactacac gctacaagct ggtaaacaaa aacagcggaa aagtcctgga tgttcttgac 89701 ggttctgtcg ataatgcagc ccagatagtc caatggaccg ataacgggtc tttgagtcaa 89761 cagtggtacc ttgtggacgt gggcggtggt tataaaaaga ttgtaaatgt aaagagcgga 89821 agagccttgg atgtaaaaga cgaatccaag gaagacggtg gagtattaat acaatatacc 89881 agcaacggcg gatataatca gcactggaaa ttcacagaca taggtgacgg gtattacaag 89941 atttccagcc gccactgcgg aaaacttata gatgtgcgaa aatggtcaac ggaagacggc 90001 ggaataattc agcagtggtc cgatgccgga ggaacaaatc agcattggaa gctggtgctt 90061 gtatcaagtc ccgagccttc accatcacct tctccccaag tggttaaagg agatgtaaac 90121 ggcgacttga aagtaaattc aacggatttt tccatgttaa gaagatattt acttaaaatc 90181 attgacaatt ttccgacaga aaacggaaaa caggctgccg atttgaacgg agacggcaga 90241 ataaactctt cggatcttac aatgctgaaa agatacttgc ttatggaagt ggatttgtaa 90301 atttacatgc aaaaattaca aatagtaaca agctatcttt tgtcatacat ctttgaactg 90361 gccaggacgg caaacaccca gttgatatgc cttaccggtc atatgcaggt ggatatctac 90421 atgcagtttg atgtgatgta cagcctcttg caaagtaaaa cacgaacaaa tgactctgtt 90481 ctgaataatc tgaataatca aaaatataaa aaaataaatc ctcaggtcca atcctgggga 90541 tttttcatat tagcaagatt tttcatatta gcaagatttt tcacattaac aggattctca 90601 tattaataat ccatattaac ggtcgagttt tactacaact ttttctccgt agagtatagg 90661 gtctatttcc aacataaggt cttttgcatc ttcaggtatt tcaaaagcca cttcacctct 90721 gacactgttt cccggtgtta tttcaccgtc aacatttcct tttaaatcgg gcacaagtgc 90781 cgtgtcataa gttaattttt ctccgtcaat caacgtaaac atcagcattg aactaaaatt 90841 aaaggtttca ttgctcttgt tctcaatact aacatcaatt gcataccaga tgttgccgtt 90901 ttcgggggaa agaaacctgt tttcaggaac ttctcttgta ccattcacaa taaatattat 90961 gttgtttagc tcaacaatat cacccagatt atatgatttt atcctgcttt cctccgaaac 91021 agcaggagtc atgggctcag ctgtttttgc tgctgtatca ggtttattga caccggtgcc 91081 ggttggcagt gctgtatctt ttcctgcatt ttgaggaaca aaaccgccgc atccgacaag 91141 cagaaaaacg accgtaaaaa tcagcaatgc tgcaaacttt ttcatgttac cactcctggt 91201 ttacttttgg ttttaaatat ataattttca agggagattt gtacggaaaa gacctttgtt 91261 aagcttgtac agctttaaat tatagcgaca aagtattttt aaatcaaatg aaaataaagg 91321 tacagcaaag taaggaatat aaaaacagcg ccttactgca atctatgtaa gacgctgttt 91381 ttagtggtcg gagtgactgg atttgaacca gcgacctctt gcaccccaag caagcactct 91441 aaccaagctg agctacaccc cgatacgctt tgttattata gcatactctt tttaaaatgt 91501 aaatactaat ttagatattt ttttatgtat aaaaattgca aaatgtgatg ataattaaaa 91561 taaaaataac caaatttttt aaggaggaca aatatatgct tagcgatgat gtgacgtcat 91621 caactgagcc tcagaagtgc aataaaatta acaaggcaaa cagaatatac ggaataataa 91681 tatatttttt atctgttgct ataatcagtc tgatagtcaa caacattata atatacaatt 91741 ggtacaatga tacaaaaaaa cggtttaagg atacttttct cagagtccaa accatgtctg 91801 aggaaaatat gaatttggaa accttaaatg aaactttgaa aaatgagtat gctttgctga 91861 aggaagacta tgacaggcta ttgaatgaaa atgaaagtat aaaaaaggag tttgaagaac 91921 ttaagaaaag aaacgctgat attgagagaa taaacaaaga attggtagaa gacaatatag 91981 aacttcaaaa tacattaaaa atggctgcag cagcaggaat aaagcctcaa aactatacag 92041 aatttaaagg actgagctca agaagctcaa ttgacagagg tgaatacatc ggaaaatttt 92101 taggaacggc gtataccccg tctaaagaag aatgcggcaa tgataacgga ataaccaatt 92161 ccggcaaacc tataattccc ggaatatctg ttgcagttga caaaaattac tggccttttg 92221 gaactgtatt ttatattaaa ggattggggt atgcggtggc catggataca ggcagtgcaa 92281 tcaaaggtaa atatagattc gactttgcag tattcgacaa aaacttcgca aacaaattgg 92341 gagcaaatta ctgggatgtc tatctggtaa aaatgggcaa cgggaaagtt gaagacatct 92401 ctctataaaa aagctccaaa aagaagtgcg tattggcact tcttttttta tgacttttta 92461 atttgcgact ttttattatt tttattaaat attattaatt taaaggaatt catgccttaa 92521 aggtagaata ggactaaggt ggcacaaaca caagcgtata acttttatct aacaaggggg 92581 gaatgaaatg gaagcaataa acgtgggagg caattttaga aaagctgcaa agcttccagt 92641 gaaactgatt attggagcaa ttgtattagt aatctttgca attctttttt ttaactcatt 92701 ttacaccgta accgatcagg aacaggctgt ggtgcttact tttggcaagg ttacaagcat 92761 agaaagcgcg ggaattcatt ttaaattgcc atatccgata cagtcggtta taaaagtacc 92821 ggtacaaatg acccaaaagc tggaactggg ctacagagac caaggtgacg gcaggtatgt 92881 aactgtggat gaagagtcaa aaatgattac gggagatttt aatatagtaa agattgactt 92941 ttttatcgaa tggaaggttt ccgatccgaa aaagtatctt tttaattcag aggatcccaa 93001 aaacatactc agagactcaa gtctaagtgc cgcacgttct gtcgtaggtt catcaaccat 93061 tgatgatgtg cttaccagcg gaaaaattgc aattgagaac gagattaagg aaaagctgat 93121 agcaagcctt gatgcctatg atatcggaat tcaggtgctg gatgtaaaaa tacaggattc 93181 ggaaccgccc acggaagaag tgaagcaggc attcaagaac gtggaaaatg caaagcagag 93241 caaggagacg gccatgaatg aggcaaacaa atacagaaac acagagattc caaaggccca 93301 ggcggaagcc gaccgtatat tgcgcaatgc agaatctcaa aagcagacaa agataaatga 93361 ggccagggga gaagtggcca agtttttaaa aatgtatgag gaatacaaga attataaaga 93421 tgtcacaaag acaaggcttt atcttgaggc aatggaagag atacttccgg gtattacggt 93481 ttatattgaa gataattctt ccggtgttca aaagcttgtt ccgctaaagc cgtttgattc 93541 agaggggggc gaatagaatg ataaaaaagg cagttttggt ttgtaccttg atatttgcgc 93601 tgattatatt gttttccggc atgtttattg tcacggaagg tgaatatgta tgcataagaa 93661 ggtttggaaa aattattgat acaaaagact ctgccgggtt atacttcaag atgccgttta 93721 ttgacagcaa gttaaccctt cccaataaaa aaatacttta caaccttccg gcgtcaaacg 93781 tattgacaaa ggacaaaaaa gacatggtta ttgacaacta tgttatctgg cagatatccg 93841 acccagtgga atttgtcaag tcaataggtt atatatcgga agcggaaaga cggattgacg 93901 cagcggttta caataccgta aaaaatacaa tgggcactct tgagcaaaac agtattatca 93961 acgaaaaact ttccggcaga ggaaaattcg ataaaattgt aaccgatgag gtcgcaaggc 94021 agcttagtgg ttatggcatt acagtgtatg atgtaaaaat aaagaagctg gatttgcctg 94081 ttgagaatga agaaaccgta tatgagagaa tgatatccga aagagaaaaa atagcagagc 94141 aatacaaggc tgaaggtgaa tatgaggcaa acaaaataaa aaatgaagtg gataaacagg 94201 taaacattat tatatcagaa gctaaagcca gcgcccagga gctaatcggt gaaggagaag 94261 ccgaatatat caggattctt tccgaggcat attcaggtga gaagaaagag ttttatgaat 94321 acgtaaaaac ccttgaagca atgaaagcat ctcttaaagg cgaaaagacg ctgatacttc 94381 ccatagattc acctataaca aaatatttta ggaatattga taattagaac tcttttaaag 94441 ataaggaaac aaaagtatac gaaaagcaaa aggagtgctg cccaatttaa taacaaagca 94501 gtgctctttt tttgtatatt tagaagtttt gcgaacaata atatgattag atatggcacc 94561 gaaagcaata tatatttgaa ttatgactta gtttccttaa ggagtgtaaa tatatggcgg 94621 acttaaaaaa actgattaaa gacatgtttg ttttcaaaga gcccgaacct cgggaagaat 94681 tcatattgga ggaaaaagag tctgaaaaaa ttgttaatgt tacggacgca catgatgaaa 94741 cttcggaaaa aaagaaaaaa ggttcgttaa gaaacctttt ttcaaaatca gccaatagtg 94801 aaaagaaaga cagcgagtcc ggcaaagaaa gcaacaacac ggaaaatatg acatgtgtaa 94861 gcaaaaatct taaagaaaat gtcgagtatt taaagaaaag gttttcaatt cctattaatg 94921 gagatgttgt tttaagagag tttgatattg taataaaaga caggaaaatt cccgcatgcc 94981 ttatatttta tgacggaatg gttaacggca tgctcataaa tcttaatatt ctgcagcccc 95041 ttatgcttct ttccaatttg gatgtaaagg gcaagaacgg ggaaaaagac attgccgagt 95101 atattcacaa aagtctggtt actcacaatc aggtaaaagt atcccatgag tttgatgaaa 95161 ttgttggaga gattaatttt ggcggttgcg gggttttcat cgacggaata gatgttgcct 95221 atgcctgtga tgtaaaggga tggcagcaca ggggagtgga caggccaaac aacgagattg 95281 ttataagagg tccgcaggaa agcttcaatg agatactcag ggtaaacacc gcccttgtaa 95341 ggaaaatctt aaaagatgaa gatcttgtgg cggaaagcat agaaatagga aaaagaagta 95401 aaactccttg ttcacttttg tatataaagg atattgcaaa cgagtctttg gttaatgaag 95461 taagaagaag gcttcaaaac ataaaaacgg attacatatt tgacaccggt gagctggagc 95521 agtatataga ggacaatacc ctaatgtcca ctccgcaaat agtggccacg gaaagacccg 95581 acagagtggc atccatgctt gctgagggga aagtggctgt gattatgtcg ggaagcccat 95641 ttgctctggt aatgcctact accaacaatg atttccttca atcggcggaa gatgcttatg 95701 taaggtttcc atatgcaaac ctgcttcgga taatgagggt tatagccata tttatgtcac 95761 tgcttttacc tgggctgtat gtggcaataa caaattatca tcacgaaatg attccaacag 95821 accttctttt tgccatagaa gcttccaggg aaagagtacc gtttccatcg gttgtggaaa 95881 taatcataat ggaatttgcc ttcgagcttg ttcgtgaagc gggtctcaga gttccaagcc 95941 ccataggtcc cacccttggc ataattgggg ctctgatact cgggcaggcg gcagttgcgg 96001 caaatattgt aagcccgatt cttataattg tagttgcggt taccggtatt gggtcttttg 96061 caataccaaa cttttcgttg ggattttctt tcaggatttt aagatttgcc tacgtttttc 96121 tagctgctat ggctggcttt ttgggcatta cttttggttt gtttgtgcaa agcattattt 96181 tgtgcaatgc aaaatctttt ggagtacctt ttatggcgcc ttttggaccg aaaaccaaga 96241 gccgtttcca ggatcagttc ttcaggtcgc ctatttggaa gcaggaaaaa aggccggatt 96301 ttttaaatac caaagatact caaaagcagc ctaagatatc gcggcaatgg agaaaaagcg 96361 aaaagaagaa aggtaagcaa taaaaaatac tgagacatta cgataggagg acttctgtgg 96421 aaggtaagat aatttttgga aagagagaag caatatcact tctgataata cttatatgca 96481 atcagttaat tttaggattt ccaagtatta tgtcgaatag tgtgggaagt gcaggatgga 96541 ttttgtcaat ctatgtatcc atacttgcat tatgcctttt tctgataata tcaaaacttt 96601 attccgcttt tgaaggaaaa gatttattgg atataagtga attcgccggc ggaaatattg 96661 caagaattat cgtcggcttg atagttgtaa tagattcggt tcttataatt tcagtcaaat 96721 taagagagta taccgaacat ataaaaataa taagctttac ccaatctcct gtcagtttta 96781 taatgctgtt ttttgcttta ggaatgatta tcagtgtcca ttttggcata gaacctttgg 96841 taagaagtac gacaattgtt cttccgattg tggcaatcgg agttgtaata gtcgttgcag 96901 gttctgtcaa aaatttcgaa ctttcaaata taatgccgat tcttggcaca gggccttatg 96961 atatttttgt aggaggcctg ccaagattgt caatattttc agggattatt tcgctttttt 97021 ttatacctcc tttcatggga ggttacaaaa atataaaaaa aatcggcgtg ttggtaatta 97081 ccatatccgg catagtttta accgtgggag tccttgctta tttgcttgta ttcccatacc 97141 ctgtttcttc aaataatgtt cttgcctttt ttgaactgtc aagagttttg gaatatggca 97201 gattttttca aaggattgag tcagtttttc ttcttacgtg gtcattggca ggcctgttgt 97261 atcttagctc gggattgtat tttgtaatat atgtattttc aaaaaccttc aagcttaaat 97321 actacagacc gcttataatt ccttttacct tgataatatt ttctttaagc ctcatacctg 97381 aaagtctgat ggagataatg tatcttgaca acaaagtaat caggtattat gcctggatag 97441 ttgcttttgg tttgccgttt gtccttttgt caattgcgag gcttgttaaa agaaaaagga 97501 ggggtatggc aaaaaaatgg gaagtaaaac caagaaaagt ttcacggtgc ttttggcatt 97561 tattatgagt ttttccgtga caggatgttt tgacaaaaga gagattgacg acctggttaa 97621 tcctatagcc attggatttg acaaaggttc aaaccattct gttcgaatga ctttgcagat 97681 tgcaattcca actaaagttg caggcggagg agaaggcggc ggagggggcg gaggtgaaga 97741 atccgtgtcc tatacaaccg ttgaagcacc gtcaatttac tccggactga atatgataaa 97801 ttcttatgta agtaaacagc ttaatatgtc gcagataaaa gtacttgttt tttctgaaga 97861 actggcgagg gaaggcattg aaaaatatat aaatgctctt atgcggggaa gagaattcag 97921 acctcattcc tatgtaatag tggcaagagg taccggaaat gctgcagaga gatatttgag 97981 ggcagtggag ccggaacttg aatcaaatcc cgccaaatac tatgaaatgc tgctgagtgc 98041 atacacctac acaggtttta cagccaatac ttcccttacg aatttttaca aaaatatggt 98101 aagtgaatcc acccaacctt tggcggttct ggctgatata agcaaatttg aaaaatccga 98161 tgacataaac atggacaatt catcatacca ggaaaaagga agggaatttc cgttggaggg 98221 agacttcaag gccggagata tgcccaaagt aggtacgata aaatcggaag taatggggct 98281 tgccgttttc aacggttcaa aaatggtggg agagcttgac ggtgaagaaa cacagcttca 98341 attgatgctg gagggaaatt tcggttattc gtatgttaca atacctgacc ccgaggcgga 98401 agattatgtg gttctgctta atataaagca gaacagaaaa cccaagagaa aagtagaaat 98461 agtagatgaa aaaccccata taaaagtaaa tatttatctt gaagcggata tactttcaat 98521 acaaagcgga gttaattacg aaagccttga aaaagtgaag atacttgaag atgctgcaga 98581 gaaatttttt gaaaaaggat ttctcagaat gctgaaaaaa accgcaaaag agtttaaaag 98641 cgatatcgca ggatttggaa aagaaatgaa aggcaaattt ttaacctggg atgagtggac 98701 aaatttcaac tggatagaaa aatatccgga ttctgaattt gaagtggacg ttgatttaaa 98761 aataagaagg cccggactta tgttaaggac atatccggca gccggtacag aggtgggtga 98821 agaataaatt atgattttta tattgagagt tattctggca ataattctgt tatgggtgtt 98881 cataaaaaca ataagctacg gaaagtggac ctgggataaa aaaaacaggc ttggtgccgt 98941 tatgattttt ctcattgcat tggccgctgt cattcttccc atatttgcat tctatataag 99001 atattaaagg tggtttgaag tatgaacaac aatacttttg gaagccatga agccatatgc 99061 cttatgatta ccatgatttc cacaaaagcc atactaagct ttccaaatat tatggcaaaa 99121 attggaggtt ctgcagcatg gattgtggca atatatatat caattcttgc aattatagtc 99181 ttttatataa caagtaagct gtattccaac tttgaaggca aggatattat tgacataggt 99241 gaaattttgg gcggaaaagc cttgaaaatc ccactgggta ttttaataat agtttttctt 99301 gttgctttgt ctgcatttta tcttagaagc ttcagcgaag aaatgaaaac catgagtttt 99361 acgatgtctc cgataggatt tattatgttg ttttttgtat tgggcatgat cataagcgct 99421 tatataggat ttgaagcttt gataagattt cagtcaataa tggttcccat tagtgtaatc 99481 agctttacat tgtttattat tgctttggca ccgtccatga acattgacaa tgtcaagccc 99541 attttaggtt tgggcccgta taacatcttt gtgaaaggag ctgttcgtat aggggatttt 99601 gcggaattaa tttttttgtt cttgctcccg ccttttataa aaaaatggga tatttttaac 99661 agggtgggat tcatcggcct tgcaatttgc gcaatagtgc tcacaagcat tacattcacg 99721 tttgtgagca tatttccgta tccggtttct acagatgatc tgctgccgac atatgaactt 99781 gcccgcatca taaaattcgg acgatttttt gaaagggcgg aaagcatttt ggtcattacc 99841 tgggcaacca ttgcttttat gtatttgagc actgcgtttt atttcttact gcatatattt 99901 aaaaaaacct ttgacctttg ttattatcag ccgcttatac tgccaatggc tctggtgatt 99961 atgagtttaa gtcttttacc gaaaagatta atggattcca ttctgctgga ggctgaagtt 100021 ttcaggaact acatatggat aatagccttc gcgatacctc ttttactttt gattgttgcc 100081 cgggctttaa acaataaaaa aagcagcaac tctccttaaa tcagcaagga gcgttgttgc 100141 ttattttaaa aaaccatttg aagtaagctc ttgacaaaaa gaaagtaaga taaactgaca 100201 aaaaggtgta ataccatgtc cagtttatat atttgatatt ttgagtatat ttttccagta 100261 tcacttcaaa aacagtaatt gctgcagtgt aaatgaagta atacagtatt cttttaaaca 100321 aactttttct ttcaggatag taaagattaa aaataacgca gattgaggga tatacaaaat 100381 attcaaatgt aaagctggcc tttgtggcat ttgcaaacag cctgacaggg tattcgatca 100441 gattgaattc tgccacaaaa aggccaagaa gccatgttat cagctgttta aaacaaaaaa 100501 tgacacttgc ttcacgtatt ttgttttttg gaacgaaaat taacagcaaa gcggcagaaa 100561 caaacaaaga agatatttca attatagttt ccgcaagcat ttttatcctc catggcaaag 100621 ttaaatttga acagacagag acattgtata aagattagtt tgcccaggcc ggttaataat 100681 ataaggcttt tttagtaata aaataccctt ggaaatttta ttaaattttt attactttct 100741 tacttaatat aataatttat attacaatta tgttacaact attgacaaaa agcgcaattg 100801 gttataatct tagtttggca aaaacaaaag cgtatatgat gtcttaggat catatactgt 100861 tttatgttat taacaatttg cctcacatgt aaaaaataca agatttgccc ccttaaataa 100921 ggtgcattaa atatgcacct tatttatatg catattttta aatattactt tatttatatt 100981 gttttgcgaa aatgtgatat gatgaaaatg tgatatgata ataaaggaac tttgaaatga 101041 agcattaaaa aaacctgttt catttctgaa acaggtttgt ggcaggggca gcaggaatcg 101101 aacccgcaac caacggtttt ggagaccgct actctaccaa ttgagctata ccccttcgac 101161 gcttttttag tatacaacag cttttctctt atgtcaatgg tttttttaaa tttttgtgta 101221 atttttgctc ttgtttgtgg taagatagaa aaggataaac ttacctgagt ttctgaagga 101281 ggagaacaat gagtaataga attggtttta taggtgcagg caatatgggc ggtgctatga 101341 taaccagcat agcacaatca ggcattattc cggcggaaaa cattttggtt tttgatgtcg 101401 acagggacaa gctttccgta ctaagggaaa aaacaggaat aaccataacg gacagtgcgc 101461 ttgagactgt ccgaaaatcg gatataatta tccttgcggt aaaaccaaac atggttaaag 101521 cagttcttaa tgatataaag ccggctgttg acaataataa aattttggtt tctgttgctg 101581 tgggaatacc gattaaattc tacaaagaaa tgctcggaga aaatataaag tttataagaa 101641 caatgcccaa cactcctgca ctggtgggag aaggaatgac tttaatgtgt tgtgacaaaa 101701 atgttgatga aaaagaggct gaacaagtaa agaaaatatt tgaatgtttc ggcaaagtag 101761 aatttttgga agaaaagctt atgagtgagg taactgcagt taccagcagc agccctgcat 101821 atgtctttat gtttattgaa gcaatggcag atgccgcagt tctttcaggc ataccaagga 101881 atctggcgta caaactttct gcccaggctg ttctgggggc tgcaaaaatg gttcttgaga 101941 ccggtaagca tccgggagag ttgaaagacc aggtgtgctc tcctgcggga accaccattg 102001 aagccgtacg ttcacttgaa aaaaaccgct tcagatatgc cataattgaa gcaatgagtg 102061 aatgcacgaa aaaagctttg gaaataggca agatgtatga ttaatgtatg tatgatgtga 102121 aatacagttg aatattatat gatttatgat taatactgta atcaatacta taattttttt 102181 taaaaagcgg aaatacaaaa gtacataagg agctgccatg aaaaaagtaa gtatctatac 102241 tgacggtgct tgttccggaa atccggggga cggaggatgg ggagcgatac tgatatacgg 102301 aaatcatgaa aaagaagtgt ccggatttga aaaagacact acaaacaaca ggatggagct 102361 tgttgctgcc attaacgctc taaagatgtt aaaggaaccg tgtgaagtgg acctttacag 102421 tgacagtgcc tatcttgtaa acggcttttt gcaaaactgg gttgaaaagt ggaagaaaaa 102481 cggctggaag acttccaaca aagaagaggt gaaaaatatg gaactgtggc aggaacttga 102541 caggctgagc aatattcaca aaatcaggtg gattaaagta aaaggccaca gtgacaatga 102601 atacaataac aggtgcgaca agctggccac agatgagatc aaaaaaaaca gcaaaaaata 102661 atttcaggag gagacgtttt aatgaactat gaagaaaaaa ccgtgtcaaa aaagcatatt 102721 tacagcggga acataataag cgtggaatgc gtcaatgttt tgcttcccaa cggaaaagaa 102781 gcctcccgtg atgtagttct gcacccggga gcatcggtcg tcatacccat aaatgacaat 102841 aatgaaattt atatggtaag gcaatacaga aagcctgttg aaaaggaact gcttgaattg 102901 cctgccggaa agcttgacaa aggtgaagat cccgaagttt gcgcaagaag agaattaaaa 102961 gaggaaacgg gtcttgaagc cgataaaata aagcatattt taagtttcta ctccggacct 103021 ggctttacca atgaaatatt gcatgtatat gccgccgtcg gacttcatga gggagaagct 103081 tgcgccgacg aagacgaatt tatttccaca aaaaagtttc cgataaacaa gctggtggaa 103141 atggtactaa ataatgaaat aaccgacgcc aaatctataa taggcatact tttggcagag 103201 aaaatagtaa aaggagaaat aaaaatataa aaaaataaaa gtataaaaaa taaaaatata 103261 aaacgcacaa gattataaaa ctgcaaaaat ataggtttgt caaaatccaa accaacggcc 103321 aggctgttat tttaagtaaa gtttacaata cattttgatg tattgtaatt ttttttattt 103381 tcaagcatag aatctttaat gtaaaaggca attgcctgga agtctttgca cgaagcttta 103441 atggaaataa tactaagagg ggataaaatg ataaaaaaaa tacacgaggt tcttatttca 103501 catataaaaa acaatataaa cacttacttt ttccttttcc tgatgtacat aggaggaata 103561 tccgcaggag cttttaccgt caatggatta agctcacttc aaaggaatga actgataaac 103621 tactttcaag gatttttgga actttttgag catcaatggg ttgacagcaa tgaaatatta 103681 agaatctcaa taatagacaa cgcaagactt gtaattgcct tatgggtcct gggagtaact 103741 atcatcggca taccctttat atatcttctt gttggtataa ggggatttat taccggcttc 103801 acgtcgggat ttataattta cattatgggc tttaaaggtg tattgtttac atttttaact 103861 attcttccaa aagaaataat tatggttccg tgtattattg cccttggcgt aaacggcatt 103921 aaattttcac ttaacattgt taaagacaaa tcagctaaac aaatgtcaaa gaacagtctg 103981 aaaacaaact tttttgcata ctgttttgta actttgtttt tttcctgctt tttacttgtc 104041 gggatactgg tagaagctta catttcgccg gtttttatga gaatgatgat ttcctgaaag 104101 ctaaatcgca gcagactgat aaaatatatt tcatgcatat aatggtattt aatgaataat 104161 ttgatataaa tcatgggtat aattgcataa atactatttt attgtaagtt atgcacaaaa 104221 aaaattaaga aaattattca atataccaaa ttattctaca taacatggga aaatattgca 104281 ttgtaactag aaatttttat ataatgtaaa ggatgaataa atatgtcctc aacttcaatg 104341 tttcgataat ggcactgtta aatattgaaa attaatataa tttaatgtat tgtgaatatg 104401 taaaaacttt atatttaaaa taaattttgc gaataaaaag gagtagaatg ctaatggaag 104461 agttggtatt gcattttctg gattttttga aaaatgacaa gcgattgtct ctcaatactt 104521 tgcaatcata taaaagagac atagaacagt acattacata tttgaaggat atgaagattc 104581 aaaatattgc aaatacgaat aaaacaactg ttatagcata tcttttgcac ttgcagaaaa 104641 agggcagggc gacttccacc atatcccgca accttgcatc aataaggtcg ttctatcaat 104701 acttaaccaa aaaagggata atatctcagg atcctacgga aaatctggag tcaccgaaag 104761 tagaaaagaa acttccacag attctctcaa cgaaagaagt ggagcttctt ttagaacagc 104821 caaagtgtga tgacttaaaa ggatacaggg acaaggcaat gcttgagctt ctttacgcaa 104881 caggaataag agtgtctgag ctcatttccc ttgatttgga tgatgtaaac cttgaaatgc 104941 aatatataag gtgcaacaag ggagcaaggg aaagaattgt tccgattggt tcagtatccg 105001 taaatgcgtt gcaggaatat ttgacgaagt ctcgaaacct tttaatacaa agacctgatg 105061 aaaaggccct gtttgttaat gtaaacggaa aaaggctgac caggcaggga ttctggaaaa 105121 taataaaaca gtacaaaaat caggcaaaga tcaataaaga cattactccc cataccttaa 105181 gacactcctt tgccgcacat cttcttgaaa acggtgcgga tctcagatca atacaggaaa 105241 tgctcgggca ttccgatata tcgtcgacac aaatttatgc tcaacttgcc aaaaacagga 105301 taaaggagat ttataagaaa acgcatccaa gagcataatt aaacaaattt aaccaaaaaa 105361 agaatgattc attaaatttg agatttgtaa tataataaaa aggtgggatg aagacatcct 105421 gcctttctta tttatcctct tttaataaaa gaaaggacca cttctatttt gaacaaagga 105481 gaaataggcc atgaaaagag ctataataat cgttttggac agtgttggca tgggagagct 105541 tcccgatgcg gcaaaatacg gtgacgaagg cagcaacaca ttaggaaata ttgcaaagaa 105601 tttacctgat tttagtctgc caaatcttga gtctttggga ttgggaaata ttgacggtat 105661 gacaggctat gagccttcaa aaaatccttt aggctcttac ggaagaatgg cggaaaaatc 105721 cgcgggcaag gacacaacaa caggtcattg ggagattgcc ggcctgatat tggataagcc 105781 ttttccggta tatccaaacg gatttcccga agatataata aaaagattcg aagacagtat 105841 aggaacaaag acattgggaa atgttccggc atcggggaca gagataatca agctgttagg 105901 agatgagcat gtaaagacag gctatccaat cgtgtacaca tcggccgaca gtgtgtttca 105961 aatagcagcc catgagaatg taatacccgt ggagaggctc tatgacatgt gccggacggc 106021 acgaaacatt cttaccggag aacatgcggt cggacgggta attgcaaggc ctttcatcgg 106081 cgagtcggga aactacaaaa gaaccgacag aaggaaagat ttttctcttg ctcctgtagg 106141 aaaaacactt ttggactatg cagttgaaaa tggttacaaa gtcaaggcag tcggaaagat 106201 tgaggatata tttggcggaa gaggtattac cgagtcagtc cacattcacg acaacatgga 106261 tggagtggac aggacccttg agtatatgag ggatgatttt gaaggtattc tttttacaaa 106321 tcttgtggac tttgacatgc tttacgggca tcgcaacgat attgccggtt atgccaatgc 106381 tttgaaagag tttgaccgaa ggattccgga aatattggca aatttgcggg aagatgacct 106441 tcttgttata actgcagatc acggctgtga cccatccacg gaaagtaccg atcattcaag 106501 agaatatgtg cctttacttg tatacggaaa gaagtttaaa agcaatgtaa acttaggtac 106561 gagaagcacc tttgcggatg ttgcaaaaac tgtggcccac tatcttggaa tcagcagcaa 106621 tttagaggga gaaagctttc ttggaagcat actgtaaagc ataatgatta ttttcggagg 106681 ttaaaactat gagaatggtt gatcttataa acaaaaaaaa gcggggagaa gctctgtccg 106741 ccgctgaaat tgattatatt gtccaaggct atacaaaggg cgaaataccg gactatcaga 106801 tgtcggcatt tttgatggct gtatatttca aaggaatgaa cagagaagag acggcaaacc 106861 ttactttatc catggtcaat tccggtgaaa cggttgacct ttcgatgatt gaaggaataa 106921 aggttgacaa gcattcttcc ggtggcgttg gagacaaaat cagtcttgta atagttccgc 106981 tttgtgcctg tgttgggata ccggttgcaa aaatgtccgg aagagggctt gggcacaccg 107041 gcggaacaat tgataagctg gaatccatag aaggatttag aaccgagctt acgaaagagg 107101 agtttgtgaa caacgtaaac aaatataaaa tggccatagt aggccaatcg ccaaatctca 107161 ctcctgcgga caaaaaaata tatgctctga gagatgttac cggtacggtg gacagcatac 107221 cgcttatagc aagctcaata atgagtaaaa aaatcgcctc cgggtgcgat tgcattgtcc 107281 tggatgtcaa ggtgggatcc ggagccttca tgaagtccgt ggacgaagcc gtgattttgg 107341 caaaaaccat ggtggaaata ggcaaagctt tgggaagaag aactgttgcg gttgtaacag 107401 acatgagcca gcctttggga tatgaagtgg gaaacgccaa cgaagttaaa gaagcaatag 107461 aaatattgaa gggccacggt gccgaggacg agacaacggt ggcactcaca attgcatccc 107521 atatggcggt attgggcggt gctttttcag attatgaatc ggcttacaac catatgcgca 107581 aattgataga atccggcaag gcagtggaaa aattaaagga attaatcaga atacaggggg 107641 gaaataccga tgtggtggac aacccaaatc ttttacccca ggccgaaaaa cacatagaag 107701 ttaaatcctc aacggcaggt tatataaatt ctgtcaatgc cgaggacata ggagtttcgg 107761 caatgcttct tggagcagga agaaagacca aaaacgacag catagatttt tcagcgggca 107821 tcacaatggt aaaaaagatt ggggattggg ttgatgaagg tgatactttg tgcatacttc 107881 acacaaacaa gtccgacttt caagaggcag aaaggctttc caaaaatgct tttgtcataa 107941 aaaacacgaa acctgaaccg attaaatatg ttcactgtgt tattgactga aaaaaacgta 108001 caaacttttt taaattaagt atatatatgc cttttcaagc ataaaaatct attgatgata 108061 aatgcttgga ggggtcttta agtgttgaga aaggttataa tctgttttac agcggcggta 108121 tttttgctga acataatggc aatatccgtt ctttcagctc cagctgtcgg cgagccggta 108181 tacgatgtcg aaaccgttgc tgatataatg gcaaatacca atgtatttga attgcaggca 108241 aagagctatg ttttgatgga tgccgaaacc ggtcagattc ttttggaaaa cagaagccac 108301 gaaagattgc ccatagcaag tataacaaaa atcatgtcca tgttgttggt aatggaagca 108361 attgattcgg ggaaaatcaa catggatgat atagtgacgg cttcagagta tgccgcaagc 108421 atgggaggtt cccaggctta tattgagccg ggcgaacagt atacggtaag agatgctcta 108481 aaagcagttg caacccactc atccaatgac gtaaccgttt ccctggccga acttgtggcc 108541 ggaagcgaac aggtgtttgt ggtgcttatg aacgaaaagg caaaagaact tggcatgaac 108601 aacacaaact tccttgattg taccgggctt acggatgaag gccattacag caccgcatat 108661 gatgttgcgc ttatgtcgag agagcttatt gtaaaacacc cgaaaattct tgagtttacc 108721 tccatctgga tggatacctt cagaaacgga gaatttcagt tggtaaacac caacaaactt 108781 gttcatttct atgaaggatg tgacggactg aaaacagggt ttacccgtgc agcaggtcac 108841 tgtctttcgg caaccgccaa aagaaatgac atgagactta tttccgtggt gttgggtgag 108901 ccggattcaa acaccagatt tgcagaaacg agaaaacttt tagactacgg atttgccaat 108961 tatgaatcaa aacaggtaaa caaaaaaggt gaagtggtca acgaaattga agtaaaaaga 109021 gcattgattc ccaaaataaa ggccctttac ggcgatgatg taaaactcct ttttgcaaga 109081 agtgacaaag gcaaggtagt aagagaagta cgattgaaaa gctctcttac agccccggtg 109141 gcaaaaggcg agaaagtggg cgaagtggta tataaaatag gtgaaaagga gattgcaaaa 109201 gtggatcttg tttccgacag ggatgtagag aaggcttctt ttggaaaatt gtttataaac 109261 atgctttcaa gctggttcag tctgggaaga agttaaatga aagcccgaaa taatccggcg 109321 gcaacttacc gtgccacccc aaaagttctt atgaggctta aaggggcacg gttttttatt 109381 ttattgaaac cggttaattt taaacaagtt tgaaaaatcg ttttgaaatg cgcaaggatt 109441 tagatataat tatatacaag tataaaatca gcattaaaaa cagggaatat accaaaagga 109501 ttgatagaca tggctttatg gggaattttt attagcgctt ttattatagg tttttcggga 109561 gcaataatgc cggggccaat gttgggagtc acaatagacg gaagcctgaa aaagagctgg 109621 atggcgggac cgttgatagt gctgggacac ggaatactgg aacttttgtt aattgccgta 109681 atgacctttg gtcttaaaga tttcttttcc aatttaacgg ttgccggatt tatcggatta 109741 tttggcggtc tttttcttgc ctggatgggc tatggtatga taaagtccgc tgtaggaaaa 109801 tcagtctctt taaacggcca gagaacaggg aataactcat atttgagaaa tcttgtattt 109861 acaggcatat atgtgagtgc aaccaatcct tactttatta tttggtgggc ttcaacagga 109921 atggagtcaa tacgccgggc ttatgagata ggattgcttg gggttttgtt ttttatgtcg 109981 gacatatttt atcggatttt gcatggtaca ctttgatatc tgtagccgtt tcaagaggaa 110041 agaagcttgt aagtgacgct gtatactcca ggattgtgct gctgctggga atatttatta 110101 tagctttttc attctatttt ataggcagtg gatgtaaaat gttattaaac ggcgtgatgt 110161 gaatgctttc tatatgtctt tttaagcatt ttcaacattt tttggactgt caatgtatcg 110221 aattataaat aagaaatctg ctatcataat taatgaaata caataggaaa tataataaag 110281 aaaaactgat tgcaaattgc agtgctgtaa aaaaaatctt tgacattagg caaaaaatga 110341 tataaaatat tttaaattta tatgaggagg aaagaaagca tggcgtatat ctatgaagag 110401 gtgtcaagaa ctttcagcga atacttacta ataccaaatc ttacaacgga aaaatgtact 110461 ccggataata tagaccttag cactcctttg gtaaaattca aaaaagatga agagtgtagt 110521 ttaaaactca atattcctat agtatccgcc attatgcagt cggtgtccaa cgacacactg 110581 gcaatagctc ttgccagatg cggaggatta tcttttatat atgcttctca gccaattgaa 110641 agccaggctg aaatggttaa aagagtaaaa aagtacaagt cgggatttgt tgtcagcgac 110701 tccaatctca ccatcgacag cacattgaag gatgtcatcg agttaaagaa cagaaccggc 110761 cattccacta tcgcaataac ggacgacggt acagcttccg gaaagcttct tggattggtc 110821 actacaaggg actatagaat aagcaggaat cctttggata aaaaagtaaa ggatttcatg 110881 acacccttct caaaactcgt tgtaggtaaa ttgggtatca gcttaagcga agcaaatgac 110941 ataatatggg aaaacaagct taattgtctt cctattgttg acgatgagca aaggcttcac 111001 tatttagttt tcagaaaaga ctatgacgac cataagcaga acccttatga actgcttgac 111061 agcaacaaaa gacttagagt cggagcagga ataaacacaa gagactacaa agaaagagtg 111121 ccggcgctgg tagatgcggg agttgacgtc ctgtgtattg attcgtccga tggattttcc 111181 gtatggcaga aatataccct ggattatata aaatcaaatt acaatataaa agtcggtgcg 111241 ggaaatgtgg ttgacaggga aggtttcttg taccttgccg aggccggagc cgactttgta 111301 aaggttggaa tcggtggagg ctccatttgt ataacccgtg aacaaaaagg aatcggaaga 111361 ggacaagcca cggccgttat tgaagtggca aaagccagag atgaatattt tgagaaaacc 111421 ggcgtttaca ttccgatttg ctcagacggc ggtattgttc acgactatca cattgttctg 111481 gccctggcaa tgggtgctga tttcgtaatg atgggaagat attttgcaag attcgatgaa 111541 agtcccacga agaaagttaa gagcggaaac ggttatgtta aagaatattg gggggaaggc 111601 tcaaacagag ccaggaactg gcagcgttac gaccatggag gggaaagtac caatctgaaa 111661 tttgaagaag gtgttgacag ctacgtacct tatgcgggta aactgagaga caaccttgaa 111721 attacactga gcaaaataaa agctacaatg tcaagctgcg gcgcagcttc cataagcgag 111781 cttcagaaaa ccgcaaggct gactgtggta tcttccacaa gcataataga aggcggggct 111841 cacgacgtta tattaaagga caaggattat taattgccgc tttttagctt gtgcctccca 111901 cgggttttag aagagtaaaa cctgtgcggg gcacattttt atacaataga aattattcct 111961 gattattttt gacagaaact attttgcaaa ataaaaatct ccataaaagg agatctttat 112021 gtattatcat tttagttaac agtcctttca atcaataaat ttaccgttct ttcagacatt 112081 atcaaacaac tcccttcatt atcagtatat ttttttttaa gttttgagtg cttgtcttaa 112141 gtttctttat acttctttat tgtggcacaa attttcggat tttaaacatg ctttttttca 112201 cattttgtta tggaaattac aacaccgtct ccgggcagaa tccaatcttt aaagccgatt 112261 tcaataccgt tgtccattgg ttcttcaata attctgtctt tatgatttcc cataaatccg 112321 aaactatgcc acgataattg ataagaaggg tcgtttaata tgaaaataac gctgtattct 112381 ttgcagggac gggttatctt gttggaaaag caaacgtcat ttaaaggcac aattgtttca 112441 ataaccatgt ctatggtaca tttctttttt acttttacat cccagaaggt atgtacttta 112501 atgcagtatg catcgctgtt ttcaaggcaa ttgtccgaaa tatcgattct ttcattaatt 112561 tctttggtaa aatccacgga atcaacagca aattttttga tttgatagag cttattgttt 112621 tccacctgtc ggactttttg catttccgcg ccaaatggaa tttttatggt acattctttt 112681 tttgacgggt ttacaatctc aaactttttt cttatggttt tggttatgta gttttctccg 112741 atgtgacatt ctattctggt tctgtagctt ttataataac attcgtttaa aagtgaagaa 112801 agttcccttt caaaaaaatt ataaaaattg tccttgtcat ggtcattgtc tctaaaataa 112861 agttctgttt caatttttgc cttcaaatcc ttcatttctt tcttcgtcag cctgttgaca 112921 aaatcgtact tgaccagtgt ttccgtagat tccacccaaa attttataag gtttatgaaa 112981 gtggatgtaa taagtgacac tcccacactt cttattgccg taagaataat atccccgaat 113041 atacctaaat aaaaggcatt ctttggagga aagaacaact caaaataaga agcggacatt 113101 attaatgtcg ttccaagtat aagcgaaatc agagaaatta tcctaagcct tttaaccaca 113161 acatatcatc tccgtaaaac ttgtcttggt ataatatatt atgtataata gaaaattatt 113221 acaatttatt tgtacaaacc tttcagggac agaattggca taaataagca acagatagaa 113281 tttttgcagg attttatctt gactcttgca aatattaatg ttacgattat ctatatttat 113341 tttgtttgca taatttttat tcaaattgga tttattgatt aatgttaatg cggaaggtgg 113401 aaaatatgtt tgtttcaaaa gctttaaagg ttaacagtaa aaatcacctg gaaatcggcg 113461 gatgtgattg cgttgatctt gtaaacaatt tcggtactcc cttgtatgta atggatgaaa 113521 gtcttataag ggaaaattgc cgtatatata aaaatgcact ggacaagtat tataacggaa 113581 acggactggt actttacgcc agcaaggctt tctgtacaat ggcaatgtgc aaaattgtcc 113641 agcaggaagg cctgggtctt gacgtggtat cgggcggaga gctgtacacc gcgattaaag 113701 cgggatttcc catggaaaag gtgtattttc acggaaacaa taaaaccatt gacgaactgg 113761 agctggcgat tgacaacaat gtaagaagaa tagtagtgga taataggcag gaacttttgc 113821 atgtaaacag aattgcagca gaaaaaggca agacagtaaa catttctttc agaataaaac 113881 ccggaattga tgctcatact catgacttta tccggacagg tcagattgac tcaaaatttg 113941 gtgttgccct tgaaaacggt gaggcaatgg aaataatagg cgaagcggtg aaactgagca 114001 atgtgaaggt ggttggactt cattgccaca taggctctca aattttcgag cttgctcctt 114061 ttgaggaagc tgcaagggtg atgcttacct ttattgcaaa aataaaggaa gagctgggta 114121 tagaaattga ggagctgaac cttggaggag gctttgggat aaaatatacc caggatgacg 114181 acccgataga gtatgaccgt tatataaaat cagtatcgga agttgtgaaa agtgtgtgcg 114241 aagacaaggg aataaagctt ccgtttatag ttatagagcc gggaaggtcc attgttgcat 114301 ctgcgggaat aacgctctac agaattggca ctataaaaga tatcaagggt gtcagaaaat 114361 atatcgccgt tgacggcgga atgaccgaca acccaagata tgccctctat cagtcaaaat 114421 atgaaggtgt tattgccaat aaagctgatg cggcaaaaac agaaaaggtt acaattgcgg 114481 gcaagtgctg tgaatccggg gacctgcttg gcaaggacgt attgcttccc gaagcggagg 114541 aaggggatat tttggcaata cttgctaccg gtgcatacaa ctattccatg tccagtaact 114601 acaaccgtat tccaagacct gcggtggttc ttgtaaaaga cggtaaagcg cgggttattg 114661 ttaaaaggga agactataac gatataataa gaaacgatat tatccctgaa gatctgtaaa 114721 atcgacttat gttgataaaa ttataaaacg agagcacatt tcaaattttg tgctcttttt 114781 ttatatattc tgttataatg aatttataaa attgtacaat gtttttgatt agatttgtaa 114841 ttatgaattt ataaattatt aaaaatttgc caaaataatc tataaattaa aaattaaaaa 114901 agagaattta tcggggagat gaaaatggag attataacgg gccatgtaaa cagcgatttt 114961 gattgtcttg catccatgat agcggcaaac aagctttatc cccacgccgt catggtaatt 115021 cccggaataa taggaaaaga tgtgagaaag tttttaaacc tttacaggga ctcatttaat 115081 tttttgtctg taaaggatat agacatagaa caagttgaca aaataattgt cgtggataca 115141 aactcaaaat caaggcttga aaaaccttta ggcaaattat ttgaaaagcc gggcgttgac 115201 atcgttgtat atgaccatca tccgccaagc gaaaacatga ttgaagctcg aaaagccgtt 115261 atcgaagata ttgggtcatg tactgctttg cttgttgatg aaatacaaaa gcttgatatt 115321 gatattactc ctttggaagc aacggttatg gctcttggga tatatgctga caccaactgt 115381 cttacattgc cgaaaacctc ttcaaaggat gcttacgccc ttgcttttct tttatccagg 115441 agagctaatt tgcaggttat agatgactat atgacaaatc ctttgaattt gaaccagcag 115501 gctcttttgg aaaagatggg cagaaatatc agggttgttg atataaacgg ttttaaagtc 115561 gctttttccg cagtggaagt tgaagattat gtggacaatg cggcttttct gacaagaaaa 115621 ctgctcgagg aaagagatta tgacgctttc ttctctgttc tcagaatgga caataaaaca 115681 tatataatcg gaagaagcct tgaagatgaa attgatgtag ggcatataat gactttcttc 115741 aacggtggag gacatcccgg tgcgggctcg ggaaaatccg atgaggcaga tcttgccaag 115801 gtggtggatt tgctcgaaaa aactcttaag aaaaatatcc gacccgtgga acgggcaaaa 115861 gatataatga gctcaccggt gaaaacgatt tctttggatt ccacaataga tgaagccaat 115921 aaaataatgt taagatacgg gcattccgga cttcccgtgg taaaagacgg tattctctgc 115981 ggaattatat cccgaaggga cgttgaaaaa gcacgcatac acggctttgg aaactcgccg 116041 gtcaaagcat atatgacaaa aaatgtaatc acgatagatc cggaaactcc gcttaaaacc 116101 attgaaaacc ttcttgttga gcataatatc ggaaggcttc cggtggtagc cggaaacaag 116161 cttttgggaa ttgttacaag gtcggatgtt atttccactc tctttgggga aaattctccc 116221 aggtggtata aaaagaacta tattgacagc caggattccg ccttgagaaa tcacaatctg 116281 gccgacaaaa taaatgctct tcccgaaagg gttaaaaaca ttcttattga agccggcaaa 116341 atagcagatg atgtgggttt gaacgcatat gtggtcggag ggtttgtgcg cgatctcata 116401 cttggagtgg agaactttga catcgatatc gtggtagagg gagacgccct gatgttttct 116461 gaaaaacttg cacagcatta tcaggcacac cttacaaagc acgacagatt tggcactgcg 116521 gtggtggtgc tggaagatga ttttaaaata gatgtggtga cagcccgaaa agagtattat 116581 gaatatcctg catcccttcc cgtagttgag gggggaacca tcaaggacga ccttttcaga 116641 agggatttta ccataaacag tatggcaata aagctgaaca aatccggctt tggcaatata 116701 gtggattttt acggaggcag aagggatctt cagatggggc ttataagaat actttacaac 116761 ctaagctttg tggaagatcc tacaagaata ttccgggcaa taagattcga acaaaggtat 116821 gactttaaaa tggaggaaaa aaccgaggaa tttgcgataa aggcaataga atccggcatt 116881 ttgggcaaag tgagccatga gaggataaac tttgagtttt ttgcaatgct gaaagaaaat 116941 aatatttggg caattttaaa aagaatggaa gacttgcgta tattaaaaaa tgtttatcct 117001 gaagttgtgc tttctgagga cttaaagaag cttctgaaaa atgcagagga aaaccttgct 117061 tgtttgaaag aaaaggtaag tgtccaggaa tctttggaca gaaccctttt gtatttacta 117121 attctttatt caaacatgag ctttgaaaaa gcggtaaaat tatcggaaaa aatgaggctt 117181 tcgaaggaat acaaaagcga aatactgaag tttattgaag caaaagacat aattctttca 117241 aatttgtccg gaaatattga tatatccaat tatgatgttt ataatgagtt aaaggaatta 117301 tctatggaaa ttttatttgt attatgcatg ctgagtaatg aaaaaaaatt cattgacaga 117361 gtaatccttt acataaacaa cctcaaaaat attaaaacat gtgtaacagg caaggattta 117421 aaggaactgg gcgtaaaacc ggggcccgaa tatgcggttc ttcttgacaa ggtacttgca 117481 gagaaactca acggcaatct gcaaacttat aatgatgagc ttgagttcc //