LOCUS NZ_ACVX01000016 73824 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00016, whole genome shotgun sequence. ACCESSION NZ_ACVX01000016 NZ_ACVX00000000 VERSION NZ_ACVX01000016.1 GI:256004614 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 73824) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 73824) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000016. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..73824 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene <1..284 /locus_tag="ClothDRAFT_1453" CDS <1..284 /locus_tag="ClothDRAFT_1453" /inference="similar to AA sequence:KEGG:Ppro_3717" /note="KEGG: ppd:Ppro_3717 integrase catalytic subunit" /codon_start=3 /transl_table=11 /product="integrase catalytic subunit" /protein_id="ZP_05429592.1" /db_xref="GI:256004615" /translation="GLNRKTVSRYLDENFNPVHAAYGKKRNGKLTPYIKAIDEYLEKG IMGSYIEEKIREMGYEGSSSTVRDYITDWKKRRKNITIKVGKMGQKQKQ" gene 422..676 /locus_tag="ClothDRAFT_1454" CDS 422..676 /locus_tag="ClothDRAFT_1454" /inference="similar to AA sequence:KEGG:Bind_3814" /note="KEGG: bid:Bind_3814 transposase IS204/IS1001/IS1096/IS1165 family protein" /codon_start=1 /transl_table=11 /product="transposase IS204/IS1001/IS1096/IS1165 family protein" /protein_id="ZP_05429593.1" /db_xref="GI:256004616" /translation="MLTDKNIDALDKWMEGAKNLNIPEINSFINVIERDMEAVRNAIK YEYSNGLVEGYINKLKVIKRIMYGRCSFETLKTKILGSKK" misc_feature <434..661 /locus_tag="ClothDRAFT_1454" /note="Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464" /db_xref="CDD:33267" gene 783..1457 /locus_tag="ClothDRAFT_1455" CDS 783..1457 /locus_tag="ClothDRAFT_1455" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pmu:PM0432 PhoB" /codon_start=1 /transl_table=11 /product="two component transcriptional regulator, winged helix family" /protein_id="ZP_05429594.1" /db_xref="GI:256004617" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /translation="MYKILIVEDDKALCNNIKEGISKWNFEGIAVQNFEDILKEFAKH NPHLVIMDINLPYFDGFYWCKKIRDISNVPVIFLSSRDSNMDIVMAVNMGGDDYVTKP FSMDVLLAKMQALIRKAYSYGQFDGQIIECNGAILNTNDGTLTYNGKNIELTKNEFKI LQLLMRNKGKIVSRDKIMRVLWESEYFISENTLTVNVNRLRSKLEDIGLKDLIVTKKS QGYMIP" misc_feature 786..1451 /locus_tag="ClothDRAFT_1455" /note="Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745" /db_xref="CDD:31088" misc_feature 795..1130 /locus_tag="ClothDRAFT_1455" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(804..809,936..938,960..962,1017..1019,1074..1076, 1083..1088) /locus_tag="ClothDRAFT_1455" /note="active site" /db_xref="CDD:29071" misc_feature 936..938 /locus_tag="ClothDRAFT_1455" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature order(945..950,954..962) /locus_tag="ClothDRAFT_1455" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature 1083..1091 /locus_tag="ClothDRAFT_1455" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature 1170..1451 /locus_tag="ClothDRAFT_1455" /note="Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase...; Region: trans_reg_C; cd00383" /db_xref="CDD:29475" misc_feature order(1242..1244,1299..1304,1356..1358,1365..1367, 1389..1394,1425..1427,1440..1442) /locus_tag="ClothDRAFT_1455" /note="DNA binding site" /db_xref="CDD:29475" gene 1454..2485 /locus_tag="ClothDRAFT_1456" CDS 1454..2485 /locus_tag="ClothDRAFT_1456" /inference="protein motif:PFAM:PF02518" /note="PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pub:SAR11_1180 phosphate regulon" /codon_start=1 /transl_table=11 /product="histidine kinase" /protein_id="ZP_05429595.1" /db_xref="GI:256004618" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /translation="MNVFKYLKDSYRQIVFFLLIILITDLVLISSVDLKKSLLDIFYL NILFFFVFLIFLAIDYTKWRNSYKDLKRALDARENIDSFIPQGNRLEEILIRDIIELK NKEKLEETEKLKKNLEEINDYITKWVHEIKIPLSVCELIADKLEDEGQYDLSKELIQE TERMNFLVNQVLHMSRASSYSQDFIVEEVNLSSLVKNVVKNNMNLFISKKIELEMGNL DFNIFTDKKWAYYVIEQIVNNACKYVDVHGKIKIQGEENDESVILTIWDNGMGIPEKD IDRIFDRGFTGENGRKTTKSTGMGLYICKKVADQLNFNIEVSSEVSKYTEFKIIFYKL SDYLKVTKM" misc_feature 1832..1990 /locus_tag="ClothDRAFT_1456" /note="Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-...; Region: HisKA; cl00080" /db_xref="CDD:153499" misc_feature 2147..2446 /locus_tag="ClothDRAFT_1456" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature order(2156..2158,2168..2170,2177..2179,2246..2248, 2252..2254,2258..2260,2264..2269,2345..2356,2402..2404, 2408..2410,2423..2428,2432..2434) /locus_tag="ClothDRAFT_1456" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature 2168..2170 /locus_tag="ClothDRAFT_1456" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature order(2258..2260,2264..2266,2345..2347,2351..2353) /locus_tag="ClothDRAFT_1456" /note="G-X-G motif; other site" /db_xref="CDD:28956" gene 2613..3377 /locus_tag="ClothDRAFT_1457" CDS 2613..3377 /locus_tag="ClothDRAFT_1457" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppr:PBPRB0368 putative ABC transporter, ATP-binding protein" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429596.1" /db_xref="GI:256004619" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /translation="MEAVLEAKNLRKEYGSKGMAFTALDGIDLKVYKGEFLGIMGPSG AGKTTLLNILSTIDRPTSGNIFYDGRDVLTMKNRELSLFRRNKIGFLFQDFNLLDNMS VEDNIALPLALSNVNVKEIKEKVEKLSEFFGLKEHLKKYPYQLSGGQKQRAAAARALI TSPSIVFADEPTGALDSKSSQELLQCLLRMNEELNATIIMVTHDAFAASYCKRILYLK DGKIHARLDKDSTRKEFFKRIIDFVGTMGGGVGELI" misc_feature 2622..3281 /locus_tag="ClothDRAFT_1457" /note="ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136" /db_xref="CDD:31331" misc_feature 2625..3278 /locus_tag="ClothDRAFT_1457" /note="This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE). They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255" /db_xref="CDD:73014" misc_feature 2733..2756 /locus_tag="ClothDRAFT_1457" /note="Walker A/P-loop; other site" /db_xref="CDD:73014" misc_feature order(2742..2747,2751..2759,2889..2891,3117..3122, 3219..3221) /locus_tag="ClothDRAFT_1457" /note="ATP binding site; other site" /db_xref="CDD:73014" misc_feature 2880..2891 /locus_tag="ClothDRAFT_1457" /note="Q-loop/lid; other site" /db_xref="CDD:73014" misc_feature 3045..3074 /locus_tag="ClothDRAFT_1457" /note="ABC transporter signature motif; other site" /db_xref="CDD:73014" misc_feature 3105..3122 /locus_tag="ClothDRAFT_1457" /note="Walker B; other site" /db_xref="CDD:73014" misc_feature 3129..3140 /locus_tag="ClothDRAFT_1457" /note="D-loop; other site" /db_xref="CDD:73014" misc_feature 3207..3227 /locus_tag="ClothDRAFT_1457" /note="H-loop/switch region; other site" /db_xref="CDD:73014" gene 3364..5232 /locus_tag="ClothDRAFT_1458" CDS 3364..5232 /locus_tag="ClothDRAFT_1458" /inference="protein motif:PFAM:PF02687" /note="PFAM: protein of unknown function DUF214; KEGG: bba:Bd1490 lipoprotein releasing system transmembrane protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF214" /protein_id="ZP_05429597.1" /db_xref="GI:256004620" /db_xref="InterPro:IPR003838" /translation="MNSFKLAVMSFKRNIKTYGMYLMAMIFSVATYYNFASMRFNPQF REAKDLTVYVQSSSVVASLLMILFLIFFIMYSGNFFLNQRKKEIAVYAFMGIDNYKIA FMFASEGLLMGIMSLVIGLSLGILFSKLFLMLLAKVALLNMRINFFISVKAIVETVVA YLVILFITFLKGYIDVVRTNLIDLINTLKKSEELPKINYLKGIASLMVIGAAYYIAVN YGKFGFGKALLWTVILVIIGTYWLFGSLLSMIIRYFISRKKFLYKGTNIISFSNIAFR IKGNYRALAAVAVSITVCITSFGTVSSLKYFVNENHKIEVPYTVTYISEKQEEIERVD EIIGKSNHNVKLKEKANFLFVPDSQVVVVKLSTFQRILTDLNVKGRDKILSKIGQLKE EAVYVERPGVFMSLLEKNDIKIGDRVYRIKAQTKVPLFGSGLPFPCVVVGEEEYETLK SEFEEKQFNGIILDNPEDTRDLTLQLAQILPENSRLYTYFIAGAAMYDLIGIVYFLGA FLFLVFVFATGSIIYFKILSESFRDKDKYEILKKLGTTDVEIKKSVSKQVGVFFLLPL IVGIIHSTVAISVLSDLMSYSLTLPTIISIGVFIIVYAIFYVFTGRKYVNVVRNQA" gene 5476..6549 /locus_tag="ClothDRAFT_1459" CDS 5476..6549 /locus_tag="ClothDRAFT_1459" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429598.1" /db_xref="GI:256004621" /translation="MSKRFSSAVIAMVVLFVLATTSFAATTETFYGGYSNVATKGSIV VELTNISSKKNVILSETEAEVYFDDPTETLNMVVAYDYDEDEEITVRDILEYYNNNGG VPTYYADTAPVVVTAKTALSTFYFCYKGDIPATYEPKFYSFEEYVYDFENKQTYTEPP EDWLLADGTSATLSEPGKYFFIFVDDGLVSSSFPGIFCLHIGDTPSETPVPVELTKIT VNPTTSKVLVNGKIVEFEAYNINGYNYFKLRDLAQAVNNTEKNFEVTWDAANNAINLI SNKPYTPSGGELAKGDGKAKVAIPTTSKIYKDGREIFLTAYNINGNNYFKLRDVAKTF DIGVTWDGATNTIGIDTSISYVE" sig_peptide 5476..5550 /locus_tag="ClothDRAFT_1459" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 at residue 25" misc_feature 6193..6522 /locus_tag="ClothDRAFT_1459" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" gene complement(6581..8374) /locus_tag="ClothDRAFT_1460" CDS complement(6581..8374) /locus_tag="ClothDRAFT_1460" /inference="protein motif:PFAM:PF00534" /note="PFAM: glycosyl transferase group 1; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: hpp:HPP12_1003 type 1 capsular polysaccharide biosynthesis protein J" /codon_start=1 /transl_table=11 /product="glycosyl transferase group 1" /protein_id="ZP_05429599.1" /db_xref="GI:256004622" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR002123" /translation="MVITLVNDTFNINNNGTTISAMRFAEALSQRGHQIRIITCGDPL KSGKDPDTGFEMFYLPELKIPIASRLAHKQNTLFAKPVRSTLKKAISGSDVVHIYQPW PLGSAAQRVARQMNIPAIAAFHIQPENITFNIGLKRFSPAAHLTYFLFYLFFYRRFSH IHCPSKFIAAQLRSHGYKARLHVISNGVHPAFCAPAKPREHTFKPIKILMIGRLSPEK RQDVLIRAVMKSRYADRIQLYFAGSGPWEKKLCHLGNKLPNPPVFGYYNRDELIKLIH ECDLYVHASDAEIEGISLIEAFACGLVPIISDSKQSAAAQFALGPQNLFKAGSPESLA EKIDYWLDHPEQLKEAEKKYAQLGKQYALEHSIRKIEKVYSSMTKNHKNEYHRSIFFR LSTRLFQIVIACPILLLWTRFVLGAKVYGRENIRGLKSGVTVCNHVHLLDSALIGVTF FPRRVVFPTLTQNVKTLWPGKLVRILGGFAIPDNIMELKAFFDEMEFLLMKNCIVHFF PEGELRPYDTGLQNFKKGAFYLAAQAQVPIVPMLITFEPPKGLIKIIRKKPVMRLHIG KPIHPMSKDIEIDSELRMKAVCKKIEAITSV" misc_feature complement(7232..8374) /locus_tag="ClothDRAFT_1460" /note="Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438" /db_xref="CDD:30787" misc_feature complement(7244..8368) /locus_tag="ClothDRAFT_1460" /note="This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-...; Region: GT1_UGDG_like; cd03817" /db_xref="CDD:99987" misc_feature complement(order(7496..7498,7565..7567,7736..7744, 8327..8329)) /locus_tag="ClothDRAFT_1460" /note="putative ADP-binding pocket; other site" /db_xref="CDD:99987" misc_feature complement(6662..7153) /locus_tag="ClothDRAFT_1460" /note="Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989" /db_xref="CDD:153251" misc_feature complement(order(6833..6835,6839..6844,6989..7000, 7049..7051,7055..7057,7064..7066)) /locus_tag="ClothDRAFT_1460" /note="putative acyl-acceptor binding pocket; other site" /db_xref="CDD:153251" gene 8651..9289 /locus_tag="ClothDRAFT_1461" CDS 8651..9289 /locus_tag="ClothDRAFT_1461" /inference="protein motif:PFAM:PF03358" /note="PFAM: NADPH-dependent FMN reductase; KEGG: ppd:Ppro_1105 NADPH-dependent FMN reductase" /codon_start=1 /transl_table=11 /product="NADPH-dependent FMN reductase" /protein_id="ZP_05429600.1" /db_xref="GI:256004623" /db_xref="InterPro:IPR005025" /translation="MKYIVAVNASPRSGWNTSQLVEAAAKGAKEAGATVDIIDLYKLE PFQGCISCFGCKLPRTFGRCVSKDGLSEVLDKIRKADGLILGSPNYLGNLTAGFRALY ERLIFQSLTYNKERPNCNEHMIPVLLITTSNCDESIYDKIGYTSMLEGYKQMLERFVG PTKIMICGNTLQVDDYSKYNWTIFDPAQKKAHHEAVFPLKLKEAYELGARLV" misc_feature 8651..>8971 /locus_tag="ClothDRAFT_1461" /note="NADPH-dependent FMN reductase; Region: FMN_red; cl00438" /db_xref="CDD:185997" misc_feature 8849..9175 /locus_tag="ClothDRAFT_1461" /note="NADPH-dependent FMN reductase; Region: FMN_red; cl00438" /db_xref="CDD:185997" gene 9448..9864 /locus_tag="ClothDRAFT_1462" CDS 9448..9864 /locus_tag="ClothDRAFT_1462" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429601.1" /db_xref="GI:256004624" /translation="MVKIKLILITIIICGVFLLAGCGDNGNGSSQPSGVSNSLQNIQG AENKKEKTNAEKFLEYAIKAADLRNFTETGNYAGIGITLQDLYKEDIINPYTGGTSLT VMNRTRDMMKDQHLSRTRLFSVDCVIIDDYMTQLKK" sig_peptide 9448..9513 /locus_tag="ClothDRAFT_1462" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.754) with cleavage site probability 0.202 at residue 22" gene 10062..11030 /locus_tag="ClothDRAFT_1463" CDS 10062..11030 /locus_tag="ClothDRAFT_1463" /inference="protein motif:PFAM:PF07833" /note="PFAM: copper amine oxidase domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="copper amine oxidase domain protein" /protein_id="ZP_05429602.1" /db_xref="GI:256004625" /db_xref="InterPro:IPR012854" /translation="MKIISKILTLVLIVTYLLSLPTSAAELPIRVVVNGTNINFPDAE PFIDENSRTQVPIRFVGEALGADVSWDGNTKKVTITLNGRKVVLQIGNKTYEVNGQQK QMDTVALLKESRTFVPVRFVSEALGATVKWNANIRTVYIDMNGDAAPSPGPTGETVKY YDGIAFNDVTDVDQYGRIKVEKLKEFLLKLADQLRFVKENGKYYIECTYPDKPEGYEW NLIIRIYNKDNSYEAYTPTTRVPDCQIPTEGSFKKEATVIKDINNISFFNVTISLEHP KTGSLGRLNIVYSTDKSDIWATFVPKSGTIPSEEYETFNFDKMFRW" sig_peptide 10062..10136 /locus_tag="ClothDRAFT_1463" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 at residue 25" misc_feature 10206..10484 /locus_tag="ClothDRAFT_1463" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" gene 11403..11981 /locus_tag="ClothDRAFT_1464" CDS 11403..11981 /locus_tag="ClothDRAFT_1464" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429603.1" /db_xref="GI:256004626" /translation="MKMVRVKLMLVAAIVCVISLLSACSGNGEGNNQPSGTPIKSLTQ STQKTQDKKEKTNAEKFLEYAIKAADLRNFTKTGNYAGVIKTLRDIYEDDIVNPYTGA TSIYAMNRTISYIDNNDMSVTRGYSVDCVVIDDYMTQLKDLDTSEVVYCVNPESKGMV FAFWFMDGVYIYEIDENGQKINEIKHFFEKEE" sig_peptide 11403..11474 /locus_tag="ClothDRAFT_1464" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.366 at residue 24" gene 12012..12554 /locus_tag="ClothDRAFT_1465" CDS 12012..12554 /locus_tag="ClothDRAFT_1465" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: shw:Sputw3181_0832 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429604.1" /db_xref="GI:256004627" /translation="MGDSWSGVRKRLEQDLLCDALKGRLKYFITKYNNAHDESGRVAI IVDGREIIQGDIFRYYKGYREVEKKIKSELGIPKRFWDGKRIVNDEVNREAEEYIDKI RLNEGIFDVWQFTDAVERFLNSNIKESLVSENPLVRLLAIVDRRVGKRTLEKLKDTVL QQPEWLQYFYRLRLQAESII" gene complement(12568..13797) /locus_tag="ClothDRAFT_1466" CDS complement(12568..13797) /locus_tag="ClothDRAFT_1466" /inference="protein motif:PFAM:PF01170" /note="PFAM: putative RNA methylase; KEGG: gme:Gmet_0845 SAM-dependent methyltransferase" /codon_start=1 /transl_table=11 /product="putative RNA methylase" /protein_id="ZP_05429605.1" /db_xref="GI:256004628" /db_xref="InterPro:IPR000241" /db_xref="InterPro:IPR000276" /db_xref="InterPro:IPR002478" /translation="MKQQRQYPKIMISRKAERSVKDGHPWIYGEEILKTEGELQNGGL VDVFAGNAFMGTGFYNSVSKITVRLISRNANDVFDARFWRRRVEYAVRYRKTVIPGAD FACCRLIHGEADHMPGLTVDRYGSLLSVQITCLGMELVKDTVYRALWDVLTEMDETIT GIYERNDIALRTREGLPEYKGWYLFDGIPAPESAVTEICENGVRYLVDVENGQKTGFF LDQKYNRAAVARIANGKRVLDCFTHTGSFGLNAALGGAEHVTCVDISQSAIDMAKANA VRNGLDGKMDFVCEDVFDLLTKLAEQKCHDYDYIILDPPAFTKSRKTVQSAARGYKEI NLKAMKLLPRGGYLATCSCSHFMTDDLFRKTLASAAKDASVSLRQIEARQQAPDHPIL WNVPETDYLKFYIFQVV" misc_feature complement(12571..13770) /locus_tag="ClothDRAFT_1466" /note="Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092" /db_xref="CDD:31289" misc_feature complement(12754..13092) /locus_tag="ClothDRAFT_1466" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature complement(order(12859..12861,12922..12930,13006..13011, 13060..13080)) /locus_tag="ClothDRAFT_1466" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" gene complement(13942..14865) /locus_tag="ClothDRAFT_1467" CDS complement(13942..14865) /locus_tag="ClothDRAFT_1467" /inference="protein motif:PFAM:PF00560" /note="PFAM: leucine-rich repeat protein; SMART: leucine-rich repeat-containing protein typical subtype; KEGG: similar to leucine-rich repeats and immunoglobulin-like domains 1" /codon_start=1 /transl_table=11 /product="leucine-rich repeat protein" /protein_id="ZP_05429606.1" /db_xref="GI:256004629" /db_xref="InterPro:IPR001611" /db_xref="InterPro:IPR003591" /translation="MKKQGIIILLLLLSFLLNSCAYSNRTTGSSNTNNSYSLIEDKRL EEAIRNQLDLSEDIELTQNHLESLTALEASSSKIKSIEGLQYAINLEELDVTNNEIED LKPLSNLEKLLDLFLGHNNIKDLSPLSNCVSLKRLYIHSSQVKSLKPLRNLVNLETIT LENNNISSLEGIENMKNLRSLYADSNKITEITPVSQLSSLETLYLSNNKIRDISPIQN LINIESLKLENNKIKDISFLKELTQLNNVNLENNQIDDISVFVELAENGAFNFKYKGL DYDINIAGNPIKTKKDDTIKKLEQLGVRVKY" sig_peptide complement(14794..14865) /locus_tag="ClothDRAFT_1467" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.478 at residue 24" misc_feature complement(14134..>14628) /locus_tag="ClothDRAFT_1467" /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs...; Region: LRR_RI; cl14636" /db_xref="CDD:176844" misc_feature complement(order(14170..14172,14176..14178,14185..14187, 14191..14193,14200..14202,14236..14238,14242..14244, 14251..14253,14257..14259,14266..14268,14302..14304, 14308..14310,14317..14319,14323..14325,14332..14334, 14368..14370,14374..14376,14383..14385,14389..14391, 14398..14400,14500..14502,14506..14508,14515..14517, 14521..14523,14530..14532,14566..14568,14572..14574, 14581..14583,14587..14589,14596..14598)) /locus_tag="ClothDRAFT_1467" /note="Leucine-rich repeats; other site" /db_xref="CDD:29015" misc_feature complement(order(14182..14184,14188..14190,14245..14247, 14377..14379,14509..14511)) /locus_tag="ClothDRAFT_1467" /note="Substrate binding site; other site" /db_xref="CDD:29015" gene 15401..16510 /locus_tag="ClothDRAFT_1468" CDS 15401..16510 /locus_tag="ClothDRAFT_1468" /inference="protein motif:PFAM:PF01663" /note="PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; PglZ domain protein; KEGG: aeh:Mlg_2780 type I phosphodiesterase/nucleotide pyrophosphatase" /codon_start=1 /transl_table=11 /product="type I phosphodiesterase/nucleotide pyrophosphatase" /protein_id="ZP_05429607.1" /db_xref="GI:256004630" /db_xref="InterPro:IPR002591" /db_xref="InterPro:IPR013973" /translation="MNTNIVYPDYSNSIANLANSILKKWGLPTNGKTLELLDRYLAKD YKNVVVILLDGMGRCIIERNLEKDGFFNTHLAGTYSSTFPSTTVAATTSIDSGLTPCE HGWLGWDCYFPQIDRNVTVFLNTDTETGEKVAEESVAWKYCWYSSVINRIDSAGGKAY YAIPFVSPYPATFEERCELIKKYCDEPGQKYIYCYCDEPDKTMHLTGCYSEESRKVIS WLERKIKSLTTELRDTLVIITADHGHVNTKRVCIKDYPNIMNCLKRIPTIEPRALNLF VKEDRRDEFEKEFTCEFGGKFLLLPKEKVLEMKLFGYGTEHKDFRNMLGDYLAVATDD LSIFNTKEKKEKFVSSHGGLTEDEMIIPLIIVEKK" misc_feature 15512..>16144 /locus_tag="ClothDRAFT_1468" /note="Sulfatase; Region: Sulfatase; cl10460" /db_xref="CDD:186998" gene 16523..16633 /locus_tag="ClothDRAFT_1469" CDS 16523..16633 /locus_tag="ClothDRAFT_1469" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429608.1" /db_xref="GI:256004631" /translation="MDVLGLKGKKTKDDAEKFVLQYIKNSGLYMVLYTCQ" gene 16971..18023 /locus_tag="ClothDRAFT_1470" CDS 16971..18023 /locus_tag="ClothDRAFT_1470" /inference="protein motif:TFAM:TIGR00157" /note="TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; GTP-binding protein HSR1-related; KEGG: pzu:PHZ_c0778 ribosome-associated GTPase" /codon_start=1 /transl_table=11 /product="ribosome small subunit-dependent GTPase A" /protein_id="ZP_05429609.1" /db_xref="GI:256004632" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR004881" /db_xref="InterPro:IPR010914" /translation="MNLIDYGFVPTMMSEDVSGFPARITAVHKERYELVCEYGYTFGR LKTSIYYAGGFEDFPTAGDFVLIDYNPDGDSRIVKTLKRKSFFSRRNPTPGKGEQAVA ANFDYVFVMQSLNHDFNLRRMERYVTLTWQSGAVPVIVLTKADLVEDCSEQVLASQKV APGVEVHAISTITGFGLDVLKDYLKPCKTVVFLGSSGVGKSSLVNALAGQEIMAVGDI REDDSKGRHTTTHRQLIMLPGGAMIIDTPGMRELGMLDDVSVGLGETFSDVVSYLGRC KFSDCRHQTEPGCVVRAAIERGELPKERWESYLKLKREANFSDDKEGYLRQKQQWSKE IAKWSKKMKKNGGIRK" misc_feature 16971..18002 /locus_tag="ClothDRAFT_1470" /note="GTPase RsgA; Reviewed; Region: PRK01889" /db_xref="CDD:179346" misc_feature 17034..17909 /locus_tag="ClothDRAFT_1470" /note="YjeQ/EngC. YjeQ (YloQ in Bacillus subtilis) represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence...; Region: YjeQ_engC; cd01854" /db_xref="CDD:57925" misc_feature order(17043..17045,17049..17051,17151..17162,17226..17228, 17277..17282,17661..17663,17667..17672,17676..17678) /locus_tag="ClothDRAFT_1470" /note="GTPase/OB domain interface; other site" /db_xref="CDD:57925" misc_feature order(17328..17333,17340..17345,17349..17354,17361..17366, 17460..17462,17751..17753,17763..17765,17769..17771, 17880..17882,17889..17891,17901..17903) /locus_tag="ClothDRAFT_1470" /note="GTPase/Zn-binding domain interface; other site" /db_xref="CDD:57925" misc_feature order(17394..17399,17403..17408,17478..17483,17559..17576) /locus_tag="ClothDRAFT_1470" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:57925" misc_feature 17394..17405 /locus_tag="ClothDRAFT_1470" /note="G4 box; other site" /db_xref="CDD:57925" misc_feature 17478..17486 /locus_tag="ClothDRAFT_1470" /note="G5 box; other site" /db_xref="CDD:57925" misc_feature 17550..17573 /locus_tag="ClothDRAFT_1470" /note="G1 box; other site" /db_xref="CDD:57925" misc_feature 17646..17669 /locus_tag="ClothDRAFT_1470" /note="Switch I region; other site" /db_xref="CDD:57925" misc_feature 17655..17657 /locus_tag="ClothDRAFT_1470" /note="G2 box; other site" /db_xref="CDD:57925" misc_feature 17703..17714 /locus_tag="ClothDRAFT_1470" /note="G3 box; other site" /db_xref="CDD:57925" misc_feature 17709..17717 /locus_tag="ClothDRAFT_1470" /note="Switch II region; other site" /db_xref="CDD:57925" gene 17981..18121 /locus_tag="ClothDRAFT_1471" CDS 17981..18121 /locus_tag="ClothDRAFT_1471" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429610.1" /db_xref="GI:256004633" /translation="MEQENEKEWGNQEMNNYTVRQIKTDEYETVRQLDSDAFRYNEFG DD" gene 18185..18604 /locus_tag="ClothDRAFT_1472" CDS 18185..18604 /locus_tag="ClothDRAFT_1472" /inference="protein motif:PFAM:PF00583" /note="PFAM: GCN5-related N-acetyltransferase; KEGG: vha:VIBHAR_03385 hypothetical protein" /codon_start=1 /transl_table=11 /product="GCN5-related N-acetyltransferase" /protein_id="ZP_05429611.1" /db_xref="GI:256004634" /db_xref="InterPro:IPR000182" /translation="MVAVTNEGFILGHGIFSALPMGNDANHVIWLNSLAVRHGEKDNH AEKRYEYQRKGIGTAIVKHGLEIAKSLGFTACMTCGNPDVYKRKMGLKNYRELGIKKD DSVEDADECIFAIELVPNGFDGTNRILSFSYYDFFQM" misc_feature <18200..18580 /locus_tag="ClothDRAFT_1472" /note="N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00443" /db_xref="CDD:185998" gene complement(18674..19552) /locus_tag="ClothDRAFT_1473" CDS complement(18674..19552) /locus_tag="ClothDRAFT_1473" /inference="protein motif:PFAM:PF01988" /note="PFAM: protein of unknown function DUF125 transmembrane; Rubrerythrin; KEGG: abu:Abu_1456 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF125 transmembrane" /protein_id="ZP_05429612.1" /db_xref="GI:256004635" /db_xref="InterPro:IPR003251" /db_xref="InterPro:IPR008217" /translation="MNYKIDADTIESLKKAQKNEITEYHIYSKLSSFIKNEHNSKVLK QIAQDELSHHNELKKFTGTDMKPNILKIYFYTFISLIFGITFGIKLMEKGESGAEKLY RELGNKIEEFKTIAKEENKHEEELIEIIEEEKLQFVGSMVLGLNDALVELTGTLAGLT FALKNTRLIALSGLITGIAATLSMAASEYLSARTEQESSRALKSSLYTGGAYVFTVAC LVFPYLLFSNYVLSLVLTIIMAILIILVFNFYISVAKDLPFKQRFFEMAGISLGVAVI SFIIGHFVRLFLGVDV" misc_feature complement(19205..19516) /locus_tag="ClothDRAFT_1473" /note="Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044" /db_xref="CDD:153103" misc_feature complement(order(19268..19270,19394..19396,19403..19405, 19493..19495)) /locus_tag="ClothDRAFT_1473" /note="diiron binding motif; other site" /db_xref="CDD:153103" misc_feature complement(18701..19141) /locus_tag="ClothDRAFT_1473" /note="CCC1-related domain of ferritin; Region: Ferritin_CCC1_C; cd02431" /db_xref="CDD:153122" gene 19983..20924 /locus_tag="ClothDRAFT_1474" CDS 19983..20924 /locus_tag="ClothDRAFT_1474" /EC_number="2.1.1.72" /inference="protein motif:TFAM:TIGR00571" /note="KEGG: rfe:RF_0123 site-specific DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase" /codon_start=1 /transl_table=11 /product="DNA adenine methylase" /protein_id="ZP_05429613.1" /db_xref="GI:256004636" /db_xref="InterPro:IPR002052" /db_xref="InterPro:IPR002294" /db_xref="InterPro:IPR012326" /db_xref="InterPro:IPR012327" /translation="MEFAISINNINSTVCAKPFVKWAGGKGQLLDTFRQYYPSTLIKG YIRRYIEPFVGGGAVLFEILQKYKVEEAFIFDINEDLINTYVVIKNDVHNLVEYLSDL ECKYLNLDEKSRKDMYYDIRDAYNSRALKNNQPDVERAAQFIFLNRTCFNGLYRVNRA GHFNVPSGDYKNPTICDEKNLYAVSSLLQRVHIFVGDYRECAGYVDKDSFVYFDPPYR PLNVTSSFTSYSKFDFTDEDQIQLAKFFSEMNDTGALLMLSNSDPKNENPDDNFFDEL YKEFFIHRIKAKRAINSNGSRRGLISELLVTNYEVKD" misc_feature 20028..20906 /locus_tag="ClothDRAFT_1474" /note="D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl00408" /db_xref="CDD:185976" gene 20934..21866 /locus_tag="ClothDRAFT_1475" CDS 20934..21866 /locus_tag="ClothDRAFT_1475" /EC_number="3.1.21.4" /inference="protein motif:PRIAM:3.1.21.4" /note="PFAM: DpmII restriction endonuclease; KEGG: cha:CHAB381_1228 restriction endonuclease R.IB" /codon_start=1 /transl_table=11 /product="Type II site-specific deoxyribonuclease" /protein_id="ZP_05429614.1" /db_xref="GI:256004637" /db_xref="InterPro:IPR007637" /translation="MKYSEIFKKRLGCKNTDEVFNYLLSHMKETIKGWDFFVAWEKVM NKVGSVEVVLNILNYLVGKENVVEEFKMLLGRYPEIAEVLPALLALREKSIKVVEPLA DNVFNYKEYVFRKKKKYNPEEIEMLAEFAEKTGLLAMFEKKNIKSVVDYAIGVEVGLD TNARKNRSGTAMEMITELFVKKICSMNNYRYLSQATSHKIKTSFGYNVSVDKSERSFD FAIDNGHKLYLVETNYYGGGGSKLKSVAGEFTTLFSFIKKETPEHGFIWITDGKGWET AKKPLRESFDKVDYVLNLDMVQKGILEDIISQGL" misc_feature 20985..21851 /locus_tag="ClothDRAFT_1475" /note="DpnII restriction endonuclease; Region: DpnII; pfam04556" /db_xref="CDD:146948" gene 21871..22860 /locus_tag="ClothDRAFT_1476" CDS 21871..22860 /locus_tag="ClothDRAFT_1476" /inference="protein motif:PFAM:PF01555" /note="PFAM: DNA methylase N-4/N-6 domain protein; putative RNA methylase; KEGG: dal:Dalk_2235 hypothetical protein" /codon_start=1 /transl_table=11 /product="DNA methylase N-4/N-6 domain protein" /protein_id="ZP_05429615.1" /db_xref="GI:256004638" /db_xref="InterPro:IPR000241" /db_xref="InterPro:IPR001091" /db_xref="InterPro:IPR002941" /translation="MGRKVKCLYCGEEYTRTQYPEHLEKNHKDGYFRLIEKIKSDIES DFSIKDTAANNDVTCAFVKKVAKESTICLEEKSKSYFADKLNIKSWEPENFNLETTTV WSFPDRGDWATHSGKYRGNWSPFIPRNVILRYSKEGETVLDQFVGSGTTLVEAKLLKR KGIGVDINPEAVNLTCRNINFEKEDCGETEVHVGDARHLGFIKDESIDLICTHPPYSN IIKYSEDIEGDLSHCDINEFLVEMEKVAKESYRVLKKGRFCAILIGDTRRKGHMIPIG FNVMQTFLRAGFKLKEIVIKEQHNCSSTGYWRNQSIKYNFLLIAHEYLFIFRK" misc_feature <22117..22395 /locus_tag="ClothDRAFT_1476" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" misc_feature 22288..22638 /locus_tag="ClothDRAFT_1476" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature order(22300..22320,22366..22371,22450..22458,22507..22509) /locus_tag="ClothDRAFT_1476" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" misc_feature 22489..>22857 /locus_tag="ClothDRAFT_1476" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cl12011" /db_xref="CDD:187159" gene 22938..23681 /locus_tag="ClothDRAFT_1477" CDS 22938..23681 /locus_tag="ClothDRAFT_1477" /inference="protein motif:PFAM:PF00106" /note="PFAM: short-chain dehydrogenase/reductase SDR; KEGG: maq:Maqu_2513 short-chain dehydrogenase/reductase SDR" /codon_start=1 /transl_table=11 /product="short-chain dehydrogenase/reductase SDR" /protein_id="ZP_05429616.1" /db_xref="GI:256004639" /db_xref="InterPro:IPR002198" /db_xref="InterPro:IPR002347" /translation="MNRGVIVTGGGHGIGKQICLDFLEAGDKVCFIDIDEKRSADFAK EHPNLFYFHGDVADPLTLKKFVEYAMEKLQRIDVLVNNACRGSKGILSSLPYEEFDYI LSVGLKAPYELSRLCRDELIKNKGRIINIASTRAFQSEPDSEAYASAKGGIVALTHAL AMSLGPDVLVNCIAPGWINVTEQQEFTREDCAAIPAGKVGTPKDISNMVLFLCQQDFI TGETIIVDGGMSKRMIYHGDWNWFYKIDK" misc_feature 22983..23624 /locus_tag="ClothDRAFT_1477" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" misc_feature 22989..23627 /locus_tag="ClothDRAFT_1477" /note="3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557" /db_xref="CDD:180126" gene 23954..25189 /locus_tag="ClothDRAFT_1478" CDS 23954..25189 /locus_tag="ClothDRAFT_1478" /inference="protein motif:PFAM:PF04282" /note="PFAM: protein of unknown function DUF438; Hemerythrin HHE cation binding domain protein; KEGG: ank:AnaeK_3310 protein of unknown function DUF438" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF438" /protein_id="ZP_05429617.1" /db_xref="GI:256004640" /db_xref="InterPro:IPR007380" /db_xref="InterPro:IPR012312" /translation="MSEIINNREYRQKVLKELIRELHDGKSVEEIKPRFEELIKGISP AEISEMEQALIMEGMPVEEIQRLCDVHAAVFKGSIEEIHRPQKPEEVPGHPIHTFKLE NAEIRKLVDNEIRPQLELYKNGDTAESLKKLREAFQKLWEIDKHYSRKENLLFPYLEK YGITAPPKVMWGVDDEIRADIKEINNKLSANAQNQNIPLEKAEEAVNRVIEMIFKEEN ILFPMALETLTEDEWAEIARTSDEIGYCMIMPEAEWKPARVDVVEKSQKEGVKSQENR GCVEFDAGCLTTEEINAMLNTLPIDITFVDKNDTVKYFTQGKERIFARPKTIIGRKVQ NCHPPASVHIVEKIIEDLKTGRKDHEDFWIKMGEKYAYIRYFAIRNEKGEYLGTIEVT QDIAPIQKITGEKRLLSDA" misc_feature 23978..25177 /locus_tag="ClothDRAFT_1478" /note="Uncharacterized conserved protein [Function unknown]; Region: COG2461" /db_xref="CDD:32573" misc_feature 23993..24235 /locus_tag="ClothDRAFT_1478" /note="Family of unknown function (DUF438); Region: DUF438; pfam04282" /db_xref="CDD:146754" gene 26046..26402 /locus_tag="ClothDRAFT_1479" CDS 26046..26402 /locus_tag="ClothDRAFT_1479" /inference="protein motif:PFAM:PF03960" /note="PFAM: arsenate reductase and related; KEGG: bba:Bd0355 putative arsenate reductase" /codon_start=1 /transl_table=11 /product="arsenate reductase" /protein_id="ZP_05429618.1" /db_xref="GI:256004641" /db_xref="InterPro:IPR006504" /db_xref="InterPro:IPR006660" /translation="MIFVCYPKCTTCQKAKKWLEANGIVFEERNIKENNPTMEELKDW HKKSGLPLNKFFNTSGLLYKELKLKDKLPSMSEEEKYNLLASDGMLVKRPILIGDDFV LVGFKETDWKASCGIE" misc_feature 26046..26378 /locus_tag="ClothDRAFT_1479" /note="Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036" /db_xref="CDD:48585" misc_feature order(26070..26072,26214..26216,26322..26324,26361..26363) /locus_tag="ClothDRAFT_1479" /note="putative ArsC-like catalytic residues; other site" /db_xref="CDD:48585" misc_feature order(26070..26072,26079..26081) /locus_tag="ClothDRAFT_1479" /note="putative TRX-like catalytic residues; other site" /db_xref="CDD:48585" gene 26632..27090 /locus_tag="ClothDRAFT_1480" CDS 26632..27090 /locus_tag="ClothDRAFT_1480" /inference="protein motif:PFAM:PF06094" /note="PFAM: AIG2 family protein; KEGG: GK20731 gene product from transcript GK20731-RA" /codon_start=1 /transl_table=11 /product="AIG2 family protein" /protein_id="ZP_05429619.1" /db_xref="GI:256004642" /db_xref="InterPro:IPR009288" /translation="MTTCNNELINCKIYTNKVFVYGTLMKDFCNYKRYLEGRISRITP GKTYGLLYHLPEGYPGLLPGSGIIEGEIVEPVDKKLLKSLDRLEGYNKGSSNNLYVRE LRNILTEDGEEVPCWIYIYADEKYAKENGILVPDGNWRNFMKRKIDMSGL" misc_feature 26683..26994 /locus_tag="ClothDRAFT_1480" /note="GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661" /db_xref="CDD:119400" misc_feature order(26683..26685,26692..26694,26698..26703,26890..26895, 26926..26928,26992..26994) /locus_tag="ClothDRAFT_1480" /note="putative active site pocket; other site" /db_xref="CDD:119400" misc_feature order(26815..26820,26824..26826,26926..26940,26944..26946, 26980..26982,26989..26991) /locus_tag="ClothDRAFT_1480" /note="dimerization interface; other site" /db_xref="CDD:119400" misc_feature 26893..26895 /locus_tag="ClothDRAFT_1480" /note="putative catalytic residue; other site" /db_xref="CDD:119400" gene 27310..27420 /locus_tag="ClothDRAFT_1481" CDS 27310..27420 /locus_tag="ClothDRAFT_1481" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429620.1" /db_xref="GI:256004643" /translation="MGGWLEKHLNAYLYYREEEKASKLIPLDLLMPIKEK" gene 27775..28764 /locus_tag="ClothDRAFT_1482" CDS 27775..28764 /locus_tag="ClothDRAFT_1482" /inference="protein motif:PFAM:PF06541" /note="PFAM: protein of unknown function DUF1113; metal-dependent phosphohydrolase HD sub domain; KEGG: dde:Dde_0966 metal dependent phosphohydrolase" /codon_start=1 /transl_table=11 /product="metal dependent phosphohydrolase" /protein_id="ZP_05429621.1" /db_xref="GI:256004644" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR010540" /translation="MAFFTYDLMESGRLPNIKWWMIFIFAFVTSMVLGYPASWAFEKL FKERLCDCTNVPLNINGRISVPTSVVFGAVSILMVKALVPLVNKGLNTLSEALLDILA YVLVSIVLIDTTLIISLMTDFRRYVVLVDGGFQNHIAVFAEHFYANPDSYYNRVMQRV GDFKLSVSKNLIEKQLCEEEFAELIKDYLEYDVIKQMDEHIHHGTTTTLQHCENVAWI CYLLNKKLNLNANEKELVEVAMLHDLFLYDWHDGDPARRIHGFVHADIACNNAIKHFG IPEKQQEAIRSHMWPLNITKIPKSREAVILCIVDKYCALIETVRLNKHFGLRH" misc_feature <27826..28134 /locus_tag="ClothDRAFT_1482" /note="Protein of unknown function (DUF1113); Region: DUF1113; pfam06541" /db_xref="CDD:148256" misc_feature 28306..>28734 /locus_tag="ClothDRAFT_1482" /note="Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418" /db_xref="CDD:31608" gene 29269..30009 /locus_tag="ClothDRAFT_1483" CDS 29269..30009 /locus_tag="ClothDRAFT_1483" /inference="protein motif:PFAM:PF00395" /note="PFAM: S-layer domain protein; KEGG: S-layer homology domain containing protein" /codon_start=1 /transl_table=11 /product="S-layer domain protein" /protein_id="ZP_05429622.1" /db_xref="GI:256004645" /db_xref="InterPro:IPR001119" /translation="MNVKKRLLSYATVLFFLCIQLLTVRAEPPVDFKGFNDIEGHWAQ FWIELNAKLGNIAGYEDSSFRPSQSVTRAEFVTMANRFFNRGGGEGLECTFTDVNEND WFFMDVAVAEKAVYISGYPDGTFRPNELITREEASVILCKLINSDPRTHADNIEFTDS DSISPWAYGYVNSLVYNHIIKGYPDNTFRPKNPVTRAEAVVLLDNALMRLMEPPIYPL HIPGSYGESPSPSETATPSPTQKNADDK" sig_peptide 29269..29349 /locus_tag="ClothDRAFT_1483" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.991 at residue 27" misc_feature 29371..29496 /locus_tag="ClothDRAFT_1483" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature 29548..29676 /locus_tag="ClothDRAFT_1483" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature 29737..29868 /locus_tag="ClothDRAFT_1483" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" gene complement(30160..30972) /locus_tag="ClothDRAFT_1484" CDS complement(30160..30972) /locus_tag="ClothDRAFT_1484" /inference="protein motif:PFAM:PF04454" /note="PFAM: Linocin_M18 bacteriocin protein; KEGG: mxa:MXAN_3556 hypothetical protein" /codon_start=1 /transl_table=11 /product="Linocin_M18 bacteriocin protein" /protein_id="ZP_05429623.1" /db_xref="GI:256004646" /db_xref="InterPro:IPR007544" /translation="MDFLSREGSPISADLWEKIDEAVVSAAKKILTGRRFISIYGPLG AGIQAINVDNISELDETEGNISVIRGRTYQHIPLINEDFSLLWRDLEFSEQMGLPVDL SSASRAATQCALREDKLIFYGNDELGYKGLLTEDGIVKFPISNWSEGENPFKDISIGL AKFIENGIVGRKALVVSPNLFVQLQRIQPGTGTTEYDRINKLLDGNIFSTPVLKDDKA VLVCSEPQNIDLVIGQDMITSYLETKNLNHYFRIMETILLRIKNKKAVIVFD" misc_feature complement(30205..30861) /locus_tag="ClothDRAFT_1484" /note="Encapsulating protein for peroxidase; Region: Linocin_M18; cl12047" /db_xref="CDD:159707" gene complement(30984..31343) /locus_tag="ClothDRAFT_1485" CDS complement(30984..31343) /locus_tag="ClothDRAFT_1485" /inference="similar to AA sequence:KEGG:Pcar_2998" /note="KEGG: pca:Pcar_2998 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429624.1" /db_xref="GI:256004647" /translation="MASFANPFAGNVPRKLTKEELIQAIRLNIAGELEAIFVYDAHVQ ATDDPVAKKVIADIRDEEKAHVGELMTLLRYLDPEEAEHFAEGEQEVKEMLEQLNITP KPLSGKTESTIGSLIDK" misc_feature complement(<31116..31274) /locus_tag="ClothDRAFT_1485" /note="Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657" /db_xref="CDD:153097" misc_feature complement(order(31149..31151,31158..31160,31248..31250)) /locus_tag="ClothDRAFT_1485" /note="dinuclear metal binding motif; other site" /db_xref="CDD:153097" gene 31617..32090 /locus_tag="ClothDRAFT_1486" CDS 31617..32090 /locus_tag="ClothDRAFT_1486" /inference="protein motif:PFAM:PF01047" /note="PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rsh:Rsph17029_0911 MarR family transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, MarR family" /protein_id="ZP_05429625.1" /db_xref="GI:256004648" /db_xref="InterPro:IPR000835" /translation="MDKNMDNNYIDKISNKEVIRQLIIFAMKHRRIMQKFLDETGVYQ AQHRLLMEIFRNPDASQNDIARSMDVSAATIAVSLKKLEKGGYIKRETVEEDNRFNKI TITEKGNKVVEQSKQIFDLVHQKVFEGFSEEEKRTLFTLLQKLNSNLDRMEAETK" misc_feature 31701..32042 /locus_tag="ClothDRAFT_1486" /note="Transcriptional regulators [Transcription]; Region: MarR; COG1846" /db_xref="CDD:32031" misc_feature 31719..32021 /locus_tag="ClothDRAFT_1486" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" gene 32111..33847 /locus_tag="ClothDRAFT_1487" CDS 32111..33847 /locus_tag="ClothDRAFT_1487" /inference="protein motif:PFAM:PF00664" /note="PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: scl:sce5644 carbohydrate ABC transporter" /codon_start=1 /transl_table=11 /product="ABC transporter transmembrane region" /protein_id="ZP_05429626.1" /db_xref="GI:256004649" /db_xref="InterPro:IPR001140" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR017940" /translation="MRRYWKYVKPYLSAFIIGPIFMIVEVIGEVIMPLLLSNIIDKGV IGGRGISYIVTMGIIMIVTALFMMTGGVGGAYFAIKASTGFANDLRKDLFRQIQKFSF NNIDQYNTGSLITRLTNDITQIQNMIQMMLRLALRAPGMLIGALIMAFAMNARLALVI LCIIPLLSLAVYFIIKVAFPLFITMQKKLDALNSTTQENLTNIRVVKSFVRERYEEEK FKKANIDLKESTMKAMKIVIFTIPAMSLAMNITILAVVWFGGKQIIAGSMTSGVLTAF VNYVIQILISLVMVSFIILNSSRTLASVRRINEVLDTDIDLTDENAVYKDKTVEYGKI EFREVYFKYYKNNEKWVLENINLVINPGETVGIIGSTGSGKSSLVQLIPRLYDVDFGE VLVDDVNVKDYSLKNLRNGVGIVLQKNVLFSGTIMENLKWGDENAGDDEVYKFAESAQ AHGFITSFEKGYDTELGQGGVNVSGGQKQRLCIARALLKKPKILILDDSTSAVDTATE AKIRESFRNELKGTTKIIIAQRISSVIDADKIIVLDDGKIVGIGNHEELMKNCETYSE IYYSQMDKKVTA" misc_feature 32111..33832 /locus_tag="ClothDRAFT_1487" /note="ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132" /db_xref="CDD:31327" misc_feature 32153..32971 /locus_tag="ClothDRAFT_1487" /note="ABC transporter transmembrane region; Region: ABC_membrane; cl00549" /db_xref="CDD:186074" misc_feature 33110..33814 /locus_tag="ClothDRAFT_1487" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature 33215..33238 /locus_tag="ClothDRAFT_1487" /note="Walker A/P-loop; other site" /db_xref="CDD:72971" misc_feature order(33224..33229,33233..33241,33359..33361,33599..33604, 33695..33697) /locus_tag="ClothDRAFT_1487" /note="ATP binding site; other site" /db_xref="CDD:72971" misc_feature 33350..33361 /locus_tag="ClothDRAFT_1487" /note="Q-loop/lid; other site" /db_xref="CDD:72971" misc_feature 33527..33556 /locus_tag="ClothDRAFT_1487" /note="ABC transporter signature motif; other site" /db_xref="CDD:72971" misc_feature 33587..33604 /locus_tag="ClothDRAFT_1487" /note="Walker B; other site" /db_xref="CDD:72971" misc_feature 33611..33622 /locus_tag="ClothDRAFT_1487" /note="D-loop; other site" /db_xref="CDD:72971" misc_feature 33683..33703 /locus_tag="ClothDRAFT_1487" /note="H-loop/switch region; other site" /db_xref="CDD:72971" gene 33847..35820 /locus_tag="ClothDRAFT_1488" CDS 33847..35820 /locus_tag="ClothDRAFT_1488" /inference="protein motif:PFAM:PF00005" /note="PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: scl:sce5645 carbohydrate ABC transporter" /codon_start=1 /transl_table=11 /product="ABC transporter related protein" /protein_id="ZP_05429627.1" /db_xref="GI:256004650" /db_xref="InterPro:IPR001140" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR017940" /translation="MSRISEERKEILLRRYGNINTTAGPGAMKPGRGKMSGGFGGPGG KRPLGFGGPRGMRGAVGGAKPKNASATINRLLAYIGRDKIKILFVFACVLGSSLASLA GSYILRPVINNLVYSDGTAKEKINNLVIGILTMACIYLAGVVCSYLQQRIMIGVSQNA LIRIREELFRKIQKLPLKYHDTHTHGDIMSRFTNDLDAVGEMLNNTMSQIFSGIITLV GTVALMFFTNWILAIIIIVTVPLMVYVGGMIGKQSRKYFIGQQQALGAVNGYIEETVT GQKVIKVFCHEETVVEEFEFLSDNLREKQRKAQFFGSIMAPVMGNLSQISYALSATIG GVLCLTLNFDIGGLAIFTNYSRHFARPISELSMQMNTIYAALAGAERVFEVMDETPEK GDSPDAIEICSEANRVEGAQPIKGEVVLKNVTFGYVPGKTVLKNINVTAKPGQKIAFV GSTGAGKTTVTNLINRFYEIEEGEILIDGINIKNIKKDSLRSNIAMVLQDTHLFSGTV RENIRYGRLDATDEEVVAAAKVACAHSFIERLPQGYDTVLDGDGANLSQGERQLLNIA RAAISKAPILILDEATSSVDTRTEKYIERGMDRLMKNRTTFVIAHRLSTVRNADLIIV LEHGEIIEQGTHEELLGMGGRYYQLYTGAVELD" misc_feature 34054..35796 /locus_tag="ClothDRAFT_1488" /note="ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132" /db_xref="CDD:31327" misc_feature 34189..34932 /locus_tag="ClothDRAFT_1488" /note="ABC transporter transmembrane region; Region: ABC_membrane; cl00549" /db_xref="CDD:186074" misc_feature 35092..35778 /locus_tag="ClothDRAFT_1488" /note="Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virluence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide...; Region: ABCC_Glucan_exporter_like; cd03254" /db_xref="CDD:73013" misc_feature 35197..35220 /locus_tag="ClothDRAFT_1488" /note="Walker A/P-loop; other site" /db_xref="CDD:73013" misc_feature order(35206..35211,35215..35223,35341..35343,35581..35586, 35677..35679) /locus_tag="ClothDRAFT_1488" /note="ATP binding site; other site" /db_xref="CDD:73013" misc_feature 35332..35343 /locus_tag="ClothDRAFT_1488" /note="Q-loop/lid; other site" /db_xref="CDD:73013" misc_feature 35509..35538 /locus_tag="ClothDRAFT_1488" /note="ABC transporter signature motif; other site" /db_xref="CDD:73013" misc_feature 35569..35586 /locus_tag="ClothDRAFT_1488" /note="Walker B; other site" /db_xref="CDD:73013" misc_feature 35593..35604 /locus_tag="ClothDRAFT_1488" /note="D-loop; other site" /db_xref="CDD:73013" misc_feature 35665..35685 /locus_tag="ClothDRAFT_1488" /note="H-loop/switch region; other site" /db_xref="CDD:73013" gene complement(35943..37697) /locus_tag="ClothDRAFT_1489" CDS complement(35943..37697) /locus_tag="ClothDRAFT_1489" /inference="protein motif:TFAM:TIGR00836" /note="TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; nitrogen regulatory protein P-II; KEGG: afw:Anae109_3636 ammonium transporter" /codon_start=1 /transl_table=11 /product="ammonium transporter" /protein_id="ZP_05429628.1" /db_xref="GI:256004651" /db_xref="InterPro:IPR001905" /db_xref="InterPro:IPR002187" /db_xref="InterPro:IPR010256" /db_xref="InterPro:IPR011304" /db_xref="InterPro:IPR017918" /translation="MNTTMIVDTLWVVFAALLVFFMNLGFAAVESGFARSKNTVNILS KNFIVFAVSSLGFMLLGWGLMFGGDNPIIGTKELFILGGSDLGFYKDTLTSTVPFWGK FFFQLVFCGTAATIVSGAVAERIKYISFIVFSFILTLFIYPVVGHWIWGGGWLANLGF MDFAGDTVVHSVGGWAALTGAIILGPRHGKYDKDGKPKAIPGHSLALAVIGLFILWLG WFGFNPGSTMSFQNPEDVVHIIVTTNTAAIAAILTATATSWSFIGKPDLGMTINGCLA GLVGITGSCAYVSVGSSLIIGAIAGIIVVFSVIFFDRIKVDDPVGATSVHLVCGVFGT LCVGLFAQEGVTSLSTVNGLFFGGGFSLLGAEIIGIIAVGAFVAASSALVWFILKKTI GIRVSLEEEIQGLDIGEHGNSAYPDFAIVAPITASGNGNGDSIVAMSQVETIKPSSVK VTPEAAIPVVNRSHPGAKMTKVTVITNQDKYTQLQNALDKIGITGLTVTNVLGYGMQK GHTEYFRGLPVKTRLLPKVQVDIVVCKIPVETVVDTVKKALYTGNMGDGKIFIYDVEN VIKIRTGEEGYDALQDEE" sig_peptide complement(37614..37697) /locus_tag="ClothDRAFT_1489" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.989) with cleavage site probability 0.978 at residue 28" misc_feature complement(36444..37682) /locus_tag="ClothDRAFT_1489" /note="Ammonium Transporter Family; Region: Ammonium_transp; cl03012" /db_xref="CDD:186546" misc_feature complement(35958..36293) /locus_tag="ClothDRAFT_1489" /note="Nitrogen regulatory protein P-II; Region: P-II; cl00412" /db_xref="CDD:185979" gene 38698..40512 /locus_tag="ClothDRAFT_1490" CDS 38698..40512 /locus_tag="ClothDRAFT_1490" /inference="protein motif:PFAM:PF00015" /note="PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pca:Pcar_0972 methyl-accepting chemotaxis protein (MCP)" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis sensory transducer" /protein_id="ZP_05429629.1" /db_xref="GI:256004652" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR004090" /translation="MFKSFNNLRIGVRIIIGFFIIVAIACIIGVVGIQNLKNVQDSYA LDYESTVDALEYVERISSHFQQIRVNVFGFALSYDSDEKREYYTERIAEHINTVDESI NGYREILSKYDASEVETEMKLLDNIQAALNEFGVLRNKMMNDLQTGLISREEFVSSFS KGGEAHNLASNVDNAIQELIDYNIDYAANQISKNKKQADNSIGLMVMVIAVGAVFALV LGLIISNGISKPITKVVAAAGKLAEGDMDITFDINSKDETGKLVDAFRNLVESTKKQA FIVEKIADGDLTVDVPIRSQKDLLGQKLSEMVHNINNLIMNIASAAEQVSAGARQISD SSMALSQGATEQASSIEELSASIEEVASKTKINADNANQANDLAEKAKTFALTGNDHM QEMLKAMDEINESSNNINKIIKVIDDIAFQTNILALNAAVEAARAGQHGKGFAVVAEE VRTLAGRSANAAKETTALIEDSIKKVEVGAKIAKETAEALEKIVSGVESVSNLVSDIN EASNEQATAIAHINQGITQVSQVVQKNSATSEESAAASEELSSQAERLKQLVEKFRLK KTSVTMDSYGELNPEIIDILGQMSKNKNKEKEAEIVLN" misc_feature <39109..>39675 /locus_tag="ClothDRAFT_1490" /note="TMAO reductase sytem sensor TorS; Region: TMAO_torS; TIGR02956" /db_xref="CDD:163083" misc_feature 39310..39510 /locus_tag="ClothDRAFT_1490" /note="Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The...; Region: HAMP; cl01054" /db_xref="CDD:154171" misc_feature 39646..40389 /locus_tag="ClothDRAFT_1490" /note="Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283" /db_xref="CDD:128579" misc_feature 39832..40395 /locus_tag="ClothDRAFT_1490" /note="Taxis toward Aspartate and Related amino acids and Homologs (TarH). The Tar chemoreceptor of Escherichia coli mediates attractant responses to aspartate, maltose, and phenol, repellent responses to Ni2+ and Co2+, and thermoresponses. These...; Region: TarH; cl00144" /db_xref="CDD:153541" gene 40791..41429 /locus_tag="ClothDRAFT_1491" CDS 40791..41429 /locus_tag="ClothDRAFT_1491" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429630.1" /db_xref="GI:256004653" /translation="MIGILSIDFDYFINASSQARDMYFPKGSDEIPENKLKSVWKERY LKYPELKKIGVIDDFHFLKKFLKELKIPKENFMKADSHKYIKSIIEKLPEKSQFKIVN IDFHHDYYHYYRGNDYYNCGNWLRRVLEERPDAKVKWIRREDSQIYCLDGIFPFEHTD DIKSVYNEKFDYIFLCKSPEWTPPHLNSKFEELCRTIEQDTILYSNMFSSVS" gene 41621..42013 /locus_tag="ClothDRAFT_1492" CDS 41621..42013 /locus_tag="ClothDRAFT_1492" /inference="protein motif:PFAM:PF01243" /note="PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: sew:SeSA_B0050 NimC/NimA family protein" /codon_start=1 /transl_table=11 /product="pyridoxamine 5'-phosphate oxidase-related FMN-binding" /protein_id="ZP_05429631.1" /db_xref="GI:256004654" /db_xref="InterPro:IPR011576" /translation="MQEVYEFLKKCGTYYLATVEGDQPRVRPFGTVDIFEGKLYIQTG KVKDVSKQIQANPKVELCAFADGKWLRVSGKLVRDDRVEAKKHMLDNYPELKGMYSAE DDNTEVLYFEDATATFYSFTEAPKVIKF" misc_feature 41621..42007 /locus_tag="ClothDRAFT_1492" /note="Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381" /db_xref="CDD:185954" gene 42165..42578 /locus_tag="ClothDRAFT_1493" CDS 42165..42578 /locus_tag="ClothDRAFT_1493" /inference="protein motif:PFAM:PF00892" /note="PFAM: protein of unknown function DUF6 transmembrane; KEGG: rlt:Rleg2_3005 protein of unknown function DUF6 transmembrane" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF6 transmembrane" /protein_id="ZP_05429632.1" /db_xref="GI:256004655" /db_xref="InterPro:IPR000620" /translation="MWMIFAILSAVFAALTSILAKVGIENVNSHLATAIRTVVVVIMA WAMVFFTHAQGGLSQISRKSWIFLILSGIATGASWLCYYKALQTGDVSKVVPIDKMSV VITIVLAFVFLREKFTAKSLIGCILLTAGTLVMVL" sig_peptide 42165..42227 /locus_tag="ClothDRAFT_1493" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.898 at residue 21" misc_feature 42168..42575 /locus_tag="ClothDRAFT_1493" /note="EamA-like transporter family; Region: EamA; cl01037" /db_xref="CDD:154161" gene 42604..43218 /locus_tag="ClothDRAFT_1494" CDS 42604..43218 /locus_tag="ClothDRAFT_1494" /inference="protein motif:PFAM:PF03551" /note="PFAM: transcriptional regulator PadR family protein; KEGG: scl:sce6005 transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, PadR-like family" /protein_id="ZP_05429633.1" /db_xref="GI:256004656" /db_xref="InterPro:IPR005149" /translation="MLYIDNIPLVEYNNIIQVEYVVINMLKHGILGLLNYGDMTGYEI MKVFRDSLSFFWTANTSQIYRELNTLKKDGFVTDIVVKQTGKPDKKVFSITESGREEL KRWLREYDYGNRNSPLCMKVFFSGELPKEENIERLREIKNEAQQAIERYSSVFETMKI YKGMVARPEDSVYWNMTVEYGIRYMKMLSEWCDCCIKILEDVEK" misc_feature 42676..43056 /locus_tag="ClothDRAFT_1494" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" misc_feature 42952..43212 /locus_tag="ClothDRAFT_1494" /note="Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400" /db_xref="CDD:150982" gene 43215..44837 /locus_tag="ClothDRAFT_1495" CDS 43215..44837 /locus_tag="ClothDRAFT_1495" /inference="protein motif:PFAM:PF02525" /note="PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: dal:Dalk_1123 NAD(P)H dehydrogenase (quinone)" /codon_start=1 /transl_table=11 /product="NAD(P)H dehydrogenase (quinone)" /protein_id="ZP_05429634.1" /db_xref="GI:256004657" /db_xref="InterPro:IPR003680" /db_xref="InterPro:IPR005025" /translation="MKILVINGSPKGDASNSLKLTKAFLEGMGDNDVREVTVSRLNLS PCKGCFCCWSKTPGKCVINDDMSRVIEDELWADIIIWSFPLYYFNVPGPLKNLIDRQL PMNLPFMTEREDGMGSGSHPSRYDMSGKRYILISTCGFYSAEKNYESVKSMFDYICGK GNYETIFCGQGELFRAPELKKRTDEYLDIVRKAGREYISTGISNETRSKLNELLYPKE VFEQMADASWGIDKETGNEVDKSLSFTRQMAALYNKGSYDGKDRVLEICYTDLGKTYQ ILLGKDGSKVFTAGSLPATTRIETPWEVWTSIARGEIRGDVALFKGMYKVTGDFSLMM NWDKYFSKTKEQQENEIDKSLTSKNKKPSMMTMLIPWITFWIAVSINANIGAIITLAV CACTPMVMARKELTVYDKISMAVVSLLSVLTLQNDMKIISIVAGYHAFGLMWLLSCFT REPLCAAYVKYDYNGEDALNNPIFMKTNYVLAVGWGILYILTAIWSWFLMRLNMIVLL QILNNAATWAMGIFTIWFVRWYPQHIALKGRR" misc_feature 43215..>43514 /locus_tag="ClothDRAFT_1495" /note="NADPH-dependent FMN reductase; Region: FMN_red; cl00438" /db_xref="CDD:185997" gene 45055..45372 /locus_tag="ClothDRAFT_1496" CDS 45055..45372 /locus_tag="ClothDRAFT_1496" /inference="protein motif:PFAM:PF03551" /note="PFAM: transcriptional regulator PadR family protein; KEGG: ype:YPO0864 hypothetical protein" /codon_start=1 /transl_table=11 /product="transcriptional regulator, PadR-like family" /protein_id="ZP_05429635.1" /db_xref="GI:256004658" /db_xref="InterPro:IPR005149" /translation="MNLEKHLPLTETTYYILLSLLEPGHGYAVMQKAEELSGGRVRIA AGTMYGALENLLKQKLIASVPSSDPRRKMYKTTEEGARVLKLEVQRLKHMVDIYNRIQ GDE" misc_feature 45097..45309 /locus_tag="ClothDRAFT_1496" /note="Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl00088" /db_xref="CDD:185792" gene 45374..45994 /locus_tag="ClothDRAFT_1497" CDS 45374..45994 /locus_tag="ClothDRAFT_1497" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429636.1" /db_xref="GI:256004659" /translation="MKKFKMFWNFDEEEKYLKDMAWQGYIFKKYSIFGFCHFESGKPQ NLNYKIDYRIFKDKKEFDNYIALFEDAGWKHVYGTKNSGNQYFLPMNEKAGTDIFSDR VSAAARYKTLYRICLANIACFIFYLCIILFSVGGDLSKLAFLTPGLWERTGRAFWSAF FFELPFVLLRMTPLVFFMTVIVFYGYWGSKAKKNYEAVMNEDTDKE" misc_feature 45395..45745 /locus_tag="ClothDRAFT_1497" /note="Protein of unknown function (DUF2812); Region: DUF2812; pfam11193" /db_xref="CDD:151635" gene 45996..46382 /locus_tag="ClothDRAFT_1498" CDS 45996..46382 /locus_tag="ClothDRAFT_1498" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429637.1" /db_xref="GI:256004660" /translation="MLNAKGFNLLFLLLFLIDAVDCLNKQPVLYLLNICQIIVRHANV VSDYYFLLNCKRHYTDYNIKSFFHLIFFVYLYFLPVESGLNVPSKNCADLLFDMKVKR NVKNITARALIKSIGEQAQKLIHRKY" gene 46431..48707 /locus_tag="ClothDRAFT_1499" CDS 46431..48707 /locus_tag="ClothDRAFT_1499" /inference="protein motif:PFAM:PF00015" /note="PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: dat:HRM2_43840 methyl-accepting chemotaxis protein" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis sensory transducer" /protein_id="ZP_05429638.1" /db_xref="GI:256004661" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /translation="MKPFKDFSNRLKTSIIRFAKVIKRFITGVISNTKKLRIKLRSKF NGLTDNKRDMDGSDNEGMSARINLEKILDFLSKPFRNIKIRTRLFVSFTALVALILIF TGMLWYKKSSEAIKTKISTYSIQITNQLGDYLNKEMDRYQKFINDFSSERTSFQDVLV QMKNPDIDAYKRRQLSESIGVYISQKLGLMGNDVELLKVVLNDEIECHYGNNSIMSKE AQKKIIENIKSSDKINNIEFYIKRDGKGIKCYPMTSRRIVSVSNAKTIGYIICVMKSD YILKQYEGIDLGEDTNIFILDSNGLVISSNSDEFVAGLEFPDKDFVKELTLKNEEKIN AFPAYINNKRYLITYTYLDEYGWYLVSNIPYSYLNKETNRLLATMVVIFIICFFATIL LSLVITRSISAPLRKLVELMKRNRDGNLTIAQTDKNKDEISVVVNNFNDMIGNIIKIV SKGNESAVNVLYSSEKIEESANKSRILTSSIAATMEEIAQGAASQAMNIANASDYMNK LYDGIKEVEGKTAVVSNIAKNTRMLSEKALGTVENLKDKSTETGEVSKQIINDIIGLN NDMKEIKKIIKMILDISGQTKLLALNATIEAARAGEAGKGFAVVASEVKKLANRTKDA SNIINDILNNIQKKTELIVDYANNTSYIIAQQLDAVNETDNAFKTILEGMLDISEQIN EVDSSVKEIVSLNEMTKNVLNTISVVSEQAASTSQEVSASTQEQLAGAEKLLQYAGEL NKMAQELNETMSIFKINS" misc_feature <47304..>47768 /locus_tag="ClothDRAFT_1499" /note="Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000" /db_xref="CDD:34605" misc_feature 47565..47768 /locus_tag="ClothDRAFT_1499" /note="Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The...; Region: HAMP; cl01054" /db_xref="CDD:154171" misc_feature 47871..48695 /locus_tag="ClothDRAFT_1499" /note="Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283" /db_xref="CDD:128579" misc_feature 48033..48701 /locus_tag="ClothDRAFT_1499" /note="Taxis toward Aspartate and Related amino acids and Homologs (TarH). The Tar chemoreceptor of Escherichia coli mediates attractant responses to aspartate, maltose, and phenol, repellent responses to Ni2+ and Co2+, and thermoresponses. These...; Region: TarH; cl00144" /db_xref="CDD:153541" gene 49120..49491 /locus_tag="ClothDRAFT_1500" CDS 49120..49491 /locus_tag="ClothDRAFT_1500" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429639.1" /db_xref="GI:256004662" /translation="MFLCNLMIPVIMIGVGYMMYKHPPKSINAIYGYRTPRSMKNDET WKFAHDCCGRLWFKLGFILLIPTIIAMLPFINGDVKTVGTVTMIIQCVQVLALVGSIF PVESSLKKNFDDDGNRRQDKN" misc_feature 49120..>49338 /locus_tag="ClothDRAFT_1500" /note="Protein of unknown function (DUF1648); Region: DUF1648; cl01712" /db_xref="CDD:154547" gene 49509..49904 /locus_tag="ClothDRAFT_1501" CDS 49509..49904 /locus_tag="ClothDRAFT_1501" /inference="protein motif:PFAM:PF00293" /note="PFAM: NUDIX hydrolase; KEGG: gsu:GSU0870 mutator MutT protein" /codon_start=1 /transl_table=11 /product="NUDIX hydrolase" /protein_id="ZP_05429640.1" /db_xref="GI:256004663" /db_xref="InterPro:IPR000086" /translation="MERIRVTAGIIINNDKVLITRRAPNENFAGGWEFPGGKIEADET PEECLARELKEELNITVSVEGFCTEVPYDYDDISIDLIAYYCTIVDGEIQMSVHDKYK WVKIEDLLNYDLLPADVPIAKRVVKEKGS" misc_feature 49518..49883 /locus_tag="ClothDRAFT_1501" /note="The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425" /db_xref="CDD:72883" misc_feature order(49518..49520,49524..49526,49617..49622,49626..49628, 49662..49664,49671..49676,49743..49745,49797..49799, 49860..49862) /locus_tag="ClothDRAFT_1501" /note="active site" /db_xref="CDD:72883" misc_feature order(49518..49520,49524..49526,49617..49622,49737..49739, 49743..49745,49860..49862) /locus_tag="ClothDRAFT_1501" /note="8-oxo-dGMP binding site; other site" /db_xref="CDD:72883" misc_feature 49617..49685 /locus_tag="ClothDRAFT_1501" /note="nudix motif; other site" /db_xref="CDD:72883" misc_feature order(49662..49664,49671..49676) /locus_tag="ClothDRAFT_1501" /note="metal-binding site" /db_xref="CDD:72883" gene 50047..51270 /locus_tag="ClothDRAFT_1502" CDS 50047..51270 /locus_tag="ClothDRAFT_1502" /inference="protein motif:PFAM:PF00753" /note="PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: pca:Pcar_2284 uncharacterized flavoprotein" /codon_start=1 /transl_table=11 /product="beta-lactamase domain protein" /protein_id="ZP_05429641.1" /db_xref="GI:256004664" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR008254" /translation="MKKLKIADGIHMLTMNVEDILFEGIWELANGVTLNSYIVQGEKT AIIDGVIGWDGIPETLYKNLEDIGVDPKNIDYLIVNHMEPDHSGWISNFRKIKDDFTV ICTDKAAKMVASFYGEDKIRVVKEGDTLDLGNGKVLSFHPVPNVHWPDTMYTYERETK TLFSCDMFGTFGRMGEHCFDDELTPEEVDFFELEGMRYYSNVMATFTPSLKKAIEKAK ELEINVIAPGHGPVYRKNPQKIIDDYSRFALYAEGTGKNEVTILWGSMYGMTEKVVNY VESILQREGIKYNKLKMPLATESEMVATVFRSAGVIIGAPTYEYKLFPPVASALNELG RKRITGKTAFRFGSYGWSGGAEKELAEIIERNNMKWNFIESVEFEGAPKDEDLARVEE RVLEFIKKMREKVVE" misc_feature 50047..51243 /locus_tag="ClothDRAFT_1502" /note="Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426" /db_xref="CDD:30775" misc_feature 50131..50562 /locus_tag="ClothDRAFT_1502" /note="Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446" /db_xref="CDD:186000" misc_feature 50821..51222 /locus_tag="ClothDRAFT_1502" /note="NADPH-dependent FMN reductase; Region: FMN_red; cl00438" /db_xref="CDD:185997" gene 51394..52104 /locus_tag="ClothDRAFT_1503" CDS 51394..52104 /locus_tag="ClothDRAFT_1503" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429642.1" /db_xref="GI:256004665" /translation="MREQILAVQRMQDYIEAHIHEEITLADLARVSHQRAFAREFGCN PKQYAENPVPLCLFKPYSVKSRYLGRRNGSMEKVKTVFVQLTERPARKVIIKRGIKAT HYFEYCEEVGCDVWSLLTSIKSISGEPVCMWLPERYRKPGTSEYVQGVEVPVDYDGII PDGFDVIELPAAKYLMFQGEPFAEEDYEQAIEEVWEAEKKYNPSVIGYEWDQDNPRIQ LEPIGSRGYIEFVPIKPV" misc_feature 51415..>51537 /locus_tag="ClothDRAFT_1503" /note="AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207" /db_xref="CDD:32389" misc_feature <51820..52002 /locus_tag="ClothDRAFT_1503" /note="Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; cl01368" /db_xref="CDD:186426" gene 52338..53396 /locus_tag="ClothDRAFT_1504" CDS 52338..53396 /locus_tag="ClothDRAFT_1504" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429643.1" /db_xref="GI:256004666" /translation="MLFCEKYGKAIDFLLEKSNIAVRYRVTRELCDGSNPNDLENLQE ELIYSERAVRLINCLKNRKEYHGSTLYAVENSLNMLVDMGFQYGKGFSEFDEVINELA DEARELPVDKNHVLRHLSHIVVVPFLLRAGFRDEWVKEFTIKRICLIHDFVTLNQYDI YDDILKYKSIPKCFRNRPIVRPDLYENGWFKIPLEYDIYGFACLMPELTVDLQSKVND IISYILDSRFQAIKDGYGILADKKRYWAMGWDPKPTDLRKDYRCNPILLKLDLLGRFS VAANSEWFTQALKLINEYTDESGIYHFPKSFLTEKDSNWILGSHMGLGENRRRKDALT IEGTFRALVIMKNILKEM" gene 53399..54214 /locus_tag="ClothDRAFT_1505" CDS 53399..54214 /locus_tag="ClothDRAFT_1505" /inference="protein motif:TFAM:TIGR00099" /note="TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; sucrose-6F-phosphate phosphohydrolase; KEGG: mmw:Mmwyl1_1759 HAD family hydrolase" /codon_start=1 /transl_table=11 /product="Cof-like hydrolase" /protein_id="ZP_05429644.1" /db_xref="GI:256004667" /db_xref="InterPro:IPR000150" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR006380" /db_xref="InterPro:IPR013200" /translation="MKTLFVSDLDGTLLRSDETLSQFTIDTINGLTEKGMLFSYATAR SLVTAKKVTKGLNSHIPVIVYNGTFVMDNVTEEILIANYFDDGIYDVFCDLFKEGIYP IVYSYIDGIEKFSYIPEKCTEGMKVFLNTRKGDKRTNKVGTIEELTAGKCFYITCIDE PEKLEPFSKKYKDRYRVIYSKDVYSEFQWLEIMPKAASKANAILQLKERLGCDRIVSF GDGENDIDMFRISDEAYAVDNAVESLKKVATGIIGSNNDDGVAKWLRANMGRL" misc_feature 53408..>53659 /locus_tag="ClothDRAFT_1505" /note="Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others...; Region: HAD_like; cd01427" /db_xref="CDD:119389" misc_feature 53411..54190 /locus_tag="ClothDRAFT_1505" /note="haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282" /db_xref="CDD:116866" misc_feature order(53420..53428,53522..53527) /locus_tag="ClothDRAFT_1505" /note="active site" /db_xref="CDD:119389" misc_feature 53420..53437 /locus_tag="ClothDRAFT_1505" /note="motif I; other site" /db_xref="CDD:119389" misc_feature 53522..53524 /locus_tag="ClothDRAFT_1505" /note="motif II; other site" /db_xref="CDD:119389" misc_feature <53984..54193 /locus_tag="ClothDRAFT_1505" /note="Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others...; Region: HAD_like; cl11391" /db_xref="CDD:187016" gene complement(54317..56629) /locus_tag="ClothDRAFT_1506" CDS complement(54317..56629) /locus_tag="ClothDRAFT_1506" /inference="protein motif:COG:COG1511" /note="KEGG: SRP ; K01421 putative membrane protein" /codon_start=1 /transl_table=11 /product="membrane protein-like protein" /protein_id="ZP_05429645.1" /db_xref="GI:256004668" /translation="MKSKMIKIISLCLCIAILASGAAYALASGKDKAENVKTAENITE NTAEKQHEEAAAKSDTFKDETVYVLANPDGTVQKIIVSDWIKNTLSSEKITDVTELEN TENIKGDESYTLGGNNTRVWDAQGNDIYYQGTIEKELPVDLSVSYKLDGKTVSADELI GKSGKVTIRFDYKNKQYETVKINGKDEKIYVPFVMLTGVLLDNDNFTNVQVSNGKIIN DGNKTAVLGFALPGLQENLAIDKEKFEIPSYVEITADTTDFSLGITVTVATNSLFNNI DVEKIDSISDLTDSMNELDDAMTKLLDGSSSLYNGICTLLDKSKELVEGINQLAEGAG KLKEGAYSLDEGAKKLYTGAAALSQGLDTLSANNDTLNDGAKKVFETILSTAETQLKA SGLTVPELTIENYASVLNEIIESLDSTKVYNQALEQVTAAVEEKRDYIKSQVVEAVRS EVEANVTAAVTEQVKAEVTKAVKEQVSEKVTANVRENVEEQVILAATGMNKASYYAAV SAGRVDAATQKAVKSAIDNKMASKEITDLISSNIDKQMQSEQVSAMISQKVDEQMQTE EIKNTIKKNTELKMAEKDIQQLIEQNTEAQIQKVISENMASEEVQSKLAAASEGAKSV IALKTSLDDYNSFYLGLMKYTAGVAQAASGASDLKNGANELQNGTGTLYKGVCSLYDG ILTMKNGLPALVDGITQLKDGAMQLSDGLSRFYEEGIQKLIDTVDDAENLIERLKATV TVSKNYKSFAGISENADGNVKFIYRTDEIK" sig_peptide complement(56546..56629) /locus_tag="ClothDRAFT_1506" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.543 at residue 28" misc_feature complement(<54479..>55777) /locus_tag="ClothDRAFT_1506" /note="Predicted membrane protein [Function unknown]; Region: COG1511" /db_xref="CDD:31700" gene complement(56619..58724) /locus_tag="ClothDRAFT_1507" CDS complement(56619..58724) /locus_tag="ClothDRAFT_1507" /inference="protein motif:COG:COG1033" /note="KEGG: MmpL efflux pump" /codon_start=1 /transl_table=11 /product="exporter of the RND superfamily protein-like protein" /protein_id="ZP_05429646.1" /db_xref="GI:256004669" /db_xref="InterPro:IPR000731" /translation="MKFGKAVVKFRVPILILTLLLMIPSILGYIGTRVNYDMLEYLPE DMETVIGQNELMNDFGKGAFSLVIVEDMPAKDVAALKEKISKVEHVDTVIWYDSIADL SIPMEMLPNKLYSAFNTENATLMAVFFDSSTSADVTMDAIREIRSICGKQCFVSGLSA LVTDLKELCEREEPIYVTIAVILACIAMFLFLDSWLVPLVFLASIGMMILLNLGSNFF LGEISYITKALSAVLQLAVTMDYSIFLWHSYNEQCETYTDKEDAMAVAINKTLASVIG SSATTIAGFIALCFMSFTMGLDLGIVMAKGVLLGVIGAVTVLPSLILILDKPLQKTKH RSLIPNMEKAAKGIVKVFPLFLIIFALLIAPAYYGYSKTNSEVYYDMGECLPEDIQYV IANSKLRENFNIASTHMLLVDTSVPSKDVRSMIKEMEQVDGVKYVISLESVIGSRVPE EILPESITSIVKSDKWRLMLISSEYKVASDSVNKQIDELNTILKKYDKNGMLIGEAPC MKDMIEITDQDFKVVNTVSIFAIFVIIALVLRSISLPFILIAVIELAIFINLGLPHYF GQSLPFIAPICISTIQLGATVDYAILMTTRYKSERIEGNDKTTSVQTALATSIPSVIV SGMELFAATFGVAIYSDIDIISSMCMLMARGAIISMLMVIFVLPALLLLCDKIICKTT LGMTKINNNLNWRLSVNEK" misc_feature complement(56685..58724) /locus_tag="ClothDRAFT_1507" /note="Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033" /db_xref="CDD:31236" sig_peptide complement(58638..58724) /locus_tag="ClothDRAFT_1507" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.711) with cleavage site probability 0.701 at residue 29" gene complement(58721..59329) /locus_tag="ClothDRAFT_1508" CDS complement(58721..59329) /locus_tag="ClothDRAFT_1508" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: rpd:RPD_2508 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429647.1" /db_xref="GI:256004670" /translation="MKVRSVIPMRIAKTGYIVISVVLLSLGILFIILPDISMRTIGKM LGAVMVLFGCIKLTGYFSKDLFRLAFQYDLQFGILVLVVGLIVLLKPSDAISLLFAAM GIALLADSLFKIQIAFDSRKFGIKKWWGILALAIMSAIVTAVLVFKPSESARVLTILL GATLITEGILNLFVAVTTVKIIKHQYPDFIEEDYFETEGENK" misc_feature complement(58790..>59059) /locus_tag="ClothDRAFT_1508" /note="Uncharacterized conserved protein [Function unknown]; Region: HdeD; cl01277" /db_xref="CDD:186412" gene complement(59511..60071) /locus_tag="ClothDRAFT_1509" CDS complement(59511..60071) /locus_tag="ClothDRAFT_1509" /inference="protein motif:PFAM:PF00440" /note="PFAM: regulatory protein TetR; KEGG: asu:Asuc_2082 TetR family transcriptional regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, TetR family" /protein_id="ZP_05429648.1" /db_xref="GI:256004671" /db_xref="InterPro:IPR001647" /translation="MANFTKKAIKDTFIELLNERPLSQITVKDIVEKCGINRNSFYYH FHDIPSLIEEIVTEEADRIVAEYRNLDSLEMSFNAAIDFAKKNRRAILNIFKSVNRDI FEQYLWKVCDYIVVSFCKTVFAEHPVSEEDRDIIIQFYKAQCFGMVIDWLRSGMKDDV HDKIHRICELQKGMLEEMIRRCIENK" misc_feature complement(59610..60059) /locus_tag="ClothDRAFT_1509" /note="probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366" /db_xref="CDD:162826" misc_feature complement(59907..60032) /locus_tag="ClothDRAFT_1509" /note="Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440" /db_xref="CDD:144144" gene 60524..61060 /locus_tag="ClothDRAFT_1510" CDS 60524..61060 /locus_tag="ClothDRAFT_1510" /inference="protein motif:TFAM:TIGR02274" /note="TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; KEGG: pat:Patl_0327 deoxycytidine triphosphate deaminase" /codon_start=1 /transl_table=11 /product="deoxycytidine triphosphate deaminase" /protein_id="ZP_05429649.1" /db_xref="GI:256004672" /db_xref="InterPro:IPR008180" /db_xref="InterPro:IPR011962" /translation="MILSDKTILKMLAEKTLVIEPLEKEQIQPASVDIRLGNTFSIVE DSCTGIINLEKEVKYKTITSDTYILLPNQFVLATTMEYFELPNNLTAFVEGRSSLGRL GLFIQNAGWVDPGFKGEITLELFNANRCAIELKAGRRVGQLVFAKMDDTALNPYKGKY QGQRGATGSRVFLDYEVK" misc_feature 60611..60958 /locus_tag="ClothDRAFT_1510" /note="Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557" /db_xref="CDD:143638" misc_feature order(60611..60616,60725..60727,60740..60745,60749..60751, 60797..60799,60803..60820,60833..60841,60854..60856, 60863..60865,60884..60886,60890..60892,60896..60898, 60902..60904,60914..60928,60935..60937,60947..60949) /locus_tag="ClothDRAFT_1510" /note="trimer interface; other site" /db_xref="CDD:143638" misc_feature order(60809..60817,60854..60862,60869..60871,60881..60886) /locus_tag="ClothDRAFT_1510" /note="active site" /db_xref="CDD:143638" gene 61454..62371 /locus_tag="ClothDRAFT_1511" CDS 61454..62371 /locus_tag="ClothDRAFT_1511" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429650.1" /db_xref="GI:256004673" /translation="MGRLFLTVLKRFWVIILSVAIATAVGIGLMANSKADEFGESGQT YNFAQQDDTLFSPQIENNYFWEKASNNKIIPFPGYLKNVSYRMQYETKARNLSISKDT FEKLFSLISEAGKVNPPKSFIEGYELLLEYESEDGLSCDIELIGFNDDKTLYFEISST EEESFIENSTGYIESAELVAFIKSIIGWKEFDIQNLSGTDEICVQVVSGIEKSDNVTI ISGADAEYITNSIIRNSTRKDAGNCGYNIKIVFKNKDSREYCGFLTGDGCPYIAIEGR VFRIDSEILNMIYEKISYNVPFGDKAILP" sig_peptide 61454..61561 /locus_tag="ClothDRAFT_1511" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.869 at residue 36" gene 62510..62857 /locus_tag="ClothDRAFT_1512" CDS 62510..62857 /locus_tag="ClothDRAFT_1512" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429651.1" /db_xref="GI:256004674" /translation="MAINIQTGLMDEAVTQGGYYTDLTEYFSSVPEIARPFLRNAKVT LSKIEEMLCKGFGRAFGFSRPITRELLVEFINYHFTILIYRFIGTGQRRRYFAPFFRS VFSEILYSYIINI" gene 63037..63258 /locus_tag="ClothDRAFT_1513" CDS 63037..63258 /locus_tag="ClothDRAFT_1513" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429652.1" /db_xref="GI:256004675" /translation="MSKLFLTVLNMSLTASYVILFVIIVRLLLKKAPKFISYALWGVV AFRLIIPFSFESMFSLMPGNTNPVLFPLI" misc_feature 63052..>63249 /locus_tag="ClothDRAFT_1513" /note="Peptidase family M48; Region: Peptidase_M48; cl12018" /db_xref="CDD:187163" gene 63682..64245 /locus_tag="ClothDRAFT_1514" CDS 63682..64245 /locus_tag="ClothDRAFT_1514" /inference="protein motif:PFAM:PF03358" /note="PFAM: NADPH-dependent FMN reductase; KEGG: bac:BamMC406_5513 NADPH-dependent FMN reductase" /codon_start=1 /transl_table=11 /product="NADPH-dependent FMN reductase" /protein_id="ZP_05429653.1" /db_xref="GI:256004676" /db_xref="InterPro:IPR005025" /translation="MNKVKILAIVGSLRKGSYNRQLALAAKEIVKDTADFTLLDYQDV PLMNEDIEYPAPDAVKRVREEVKAANGIWFFTPEYNHFFPGVLKNLIDWLSRPVSENE PQVLAGKPAAISGISLGMSGTAIAQDHLVTLISFLDMKVMNVPRVTVPNAWQYVDDQG KLIMESIYPHLEKQAKAFVNFIQAKCL" misc_feature 63694..64143 /locus_tag="ClothDRAFT_1514" /note="NADPH-dependent FMN reductase; Region: FMN_red; cl00438" /db_xref="CDD:185997" gene complement(64461..67163) /locus_tag="ClothDRAFT_1515" CDS complement(64461..67163) /locus_tag="ClothDRAFT_1515" /inference="protein motif:PFAM:PF03425" /note="PFAM: Carbohydrate binding family 11; glycoside hydrolase family 5; cellulosome protein dockerin type I; KEGG: sde:Sde_2490 2-isopropylmalate synthase" /codon_start=1 /transl_table=11 /product="Carbohydrate binding family 11" /protein_id="ZP_05429654.1" /db_xref="GI:256004677" /db_xref="InterPro:IPR001547" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR005087" /translation="MKKRLLVSFLVLSIIVGLLSFQSLGNYNSGLKIGAWVGTQPSES AIKSFQELQGRKLDIVHQFINWSTDFSWVRPYADAVYNNGSILMITWEPWEYNTVDIK NGKADAYITRMAQDMKAYGKEIWLRPLHEANGDWYPWAIGYSSRVNTNETYIAAFRHI VDIFRANGATNVKWVFNVNCDNVGNGTSYLGHYPGDNYVDYTSIDGYNWGTTQSWGSQ WQSFDQVFSRAYQALASINKPIIIAEFASAEIGGNKARWITEAYNSIRTSYNKVIAAV WFHENKETDWRINSSPEALAAYREAIGAGSSNPTPTPTWTSAPPSSSPKAVDPFEMVR KMGMGTNLGNTLEAPYEGSWSKSAMEYYFDDFKAAGYKNVRIPVRWDNHTMRTYPYTI DKAFLDRVEQVVDWSLSRGFVTIINSHHDDWIKEDYNGNIERFEKIWEQIAERFKNKS ENLLFEIMNEPFGNITDEQIDDMNSRILKIIRKTNPTRIVIIGGGYWNSYNTLVNIKI PDDPYLIGTFHYYDPYEFTHKWRGTWGTQEDMDTVVRVFDFVKSWSDRNNIPVYLGEF AVMAYADRTSRVKWYDFISDAALERGFACSVWDNGVFGSLDNDMAIYNRDTRTFDTEI LNALFNPGTYPSYSPKPSPTPRPTKPPVTPAVGEKMLDDFEGVLNWGSYSGEGAKVST KIVSGKTGNGMEVSYTGTTDGYWGTVYSLPDGDWSKWLKISFDIKSVDGSANEIRFMI AEKSINGVGDGEHWVYSITPDSSWKTIEIPFSSFRRRLDYQPPGQDMSGTLDLDNIDS IHFMYANNKSGKFVVDNIKLIGATSDPTPSIKHGDLNFDNAVNSTDLLMLKRYILKSL ELGTSEQEEKFKKAADLNRDNKVDSTDLTILKRYLLKAISEIPI" sig_peptide complement(67086..67163) /locus_tag="ClothDRAFT_1515" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.924 at residue 26" misc_feature complement(66297..>66989) /locus_tag="ClothDRAFT_1515" /note="Glycosyl hydrolase family 26; Region: Glyco_hydro_26; cl09200" /db_xref="CDD:158452" misc_feature complement(65340..66110) /locus_tag="ClothDRAFT_1515" /note="Cellulase (glycosyl hydrolase family 5); Region: Cellulase; cl12144" /db_xref="CDD:159804" misc_feature complement(64701..65201) /locus_tag="ClothDRAFT_1515" /note="Carbohydrate binding domain (family 11); Region: CBM_11; pfam03425" /db_xref="CDD:146191" misc_feature complement(64605..64667) /locus_tag="ClothDRAFT_1515" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature complement(64488..64550) /locus_tag="ClothDRAFT_1515" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" gene complement(67434..69119) /locus_tag="ClothDRAFT_1516" CDS complement(67434..69119) /locus_tag="ClothDRAFT_1516" /inference="protein motif:PFAM:PF00150" /note="PFAM: glycoside hydrolase family 5; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 5" /protein_id="ZP_05429655.1" /db_xref="GI:256004678" /db_xref="InterPro:IPR001547" /translation="MKCRYMDYLINCELDSLPNEKSEKINKHISTCMDCRNYLGALMI SKKYIAKEPEMDKYFYMRVINAIDPDRYKKSKLTFKILSSLERLKPAFKASLGTLAVF VAVALLITGGIFDNLGNWIAKSSNNRSNTGETTNLTFLRTDGQNIVTGTGEIFHIRGV TLTNNFWGNWVNGESEKLQSQGMDPIIRPLVQDAWVLTDDDFERIKDLGCNTVLYDIN YQLFAEDNPNREENLKKLKEHIRRFSSMDIYTAVMLMAPPGLDSINDAYEKYKHGSER IKSVFEDDTYYEQWVEMWKYLAEELKDFKGVAGYGLINQPRAPSESEGGIGIFRERLN NVCREIRKIDKNHIIFVPEYNSREANPGESYWNEKTNSYVIDNGEQGIIWERGLVKVD SSNVVYLFHFFEPYNFVNDGVGDFDAESLEAQVRKRYEWAKNVGRAPLLTEYGISRVN SVDKRVQWLETVHDIFDKYGISASYFQYKNAVGAFINVKTGFNALYGEYVSWDSEIGL NPFYFVNEHVATSAKENHFDEALKEYYLKGKNLKKISILDNQPILETLQNFWK" misc_feature complement(67695..68684) /locus_tag="ClothDRAFT_1516" /note="Cellulase (glycosyl hydrolase family 5); Region: Cellulase; cl12144" /db_xref="CDD:159804" gene complement(69116..69733) /locus_tag="ClothDRAFT_1517" CDS complement(69116..69733) /locus_tag="ClothDRAFT_1517" /inference="protein motif:TFAM:TIGR02937" /note="TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: tau:Tola_0843 RNA polymerase, sigma-24 subunit, ECF subfamily" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma-24 subunit, ECF subfamily" /protein_id="ZP_05429656.1" /db_xref="GI:256004679" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR014284" /translation="MLLIKLSFVLFLYKGVDKLLDESTLISNTLNGDIQSFALLVQAY QGQLYNFIYKMTKSKEDTEDILQDVFVKVYNNLYKYNNNYRFSTWIYSITLNTIKSSL KKKKLRPSGCNIDDFIEEIPSFDDSPELLIEVKEHYKEIIEIIDSLKEKQKTAFILRY IRDFSYKEIGKIMGISQEAAKMKVHRAKSILAKKIAGMRKEGDFE" misc_feature complement(69149..69631) /locus_tag="ClothDRAFT_1517" /note="RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937" /db_xref="CDD:163078" misc_feature complement(69440..69616) /locus_tag="ClothDRAFT_1517" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature complement(69170..69316) /locus_tag="ClothDRAFT_1517" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cd06171" /db_xref="CDD:100119" misc_feature complement(order(69170..69172,69176..69181,69185..69193, 69197..69202,69206..69208,69236..69241,69257..69259, 69287..69289)) /locus_tag="ClothDRAFT_1517" /note="DNA binding residues" /db_xref="CDD:100119" gene 70634..70861 /locus_tag="ClothDRAFT_1518" CDS 70634..70861 /locus_tag="ClothDRAFT_1518" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429657.1" /db_xref="GI:256004680" /translation="MELVIVLPPQVTCRAYDEFDESCIEKCDNGWFRVTAKVAEDNWL YSFLRSLGKDVCIISPEHLKEKFKQEDIKTL" misc_feature <70637..70843 /locus_tag="ClothDRAFT_1518" /note="Predicted transcriptional regulator [Transcription]; Region: COG2378" /db_xref="CDD:32525" gene 70980..71525 /locus_tag="ClothDRAFT_1519" CDS 70980..71525 /locus_tag="ClothDRAFT_1519" /inference="protein motif:PFAM:PF08020" /note="PFAM: protein of unknown function DUF1706; KEGG: hhe:HH1054 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1706" /protein_id="ZP_05429658.1" /db_xref="GI:256004681" /db_xref="InterPro:IPR012550" /translation="MPRPATKEDLITAANEQFDKMWALIDSMTEEELAMPFDFGDDPK DKEAHWKRDKNLRDILIHLYEWHQLLLNWVTSNRKGNSVPFLPEPYTWKTYGDLNMKF WVKHQSTPYEDAKKMLLQSHKEVLALIEGFSNEELFEKQYFKWTGTTSLGSYCVSATS SHYDWAIKKIKRQIKKLRSRS" misc_feature 70980..71477 /locus_tag="ClothDRAFT_1519" /note="Protein of unknown function (DUF1706); Region: DUF1706; cl01748" /db_xref="CDD:154568" gene 71786..72238 /locus_tag="ClothDRAFT_1520" CDS 71786..72238 /locus_tag="ClothDRAFT_1520" /inference="protein motif:PFAM:PF00578" /note="PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: avi:Avi_1886 bacterioferritin comigratory protein" /codon_start=1 /transl_table=11 /product="alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen" /protein_id="ZP_05429659.1" /db_xref="GI:256004682" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013740" /translation="MLEVGTKAPDFELPDQNGKMHKLSDYRGKKVILYFYSKDNTAGC TKQACGYSERYPQFVEKGAVVLGVSKDTVASHKKFEEKHGLAITLLSDPERKAIEAYD VWKEKKVCGKVCMGVVRTTYLIDEEGIIVKANDKVKAEDDAERMLAEL" misc_feature 71801..72229 /locus_tag="ClothDRAFT_1520" /note="Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by...; Region: PRX_BCP; cd03017" /db_xref="CDD:48566" misc_feature order(71906..71908,71915..71917,72140..72142) /locus_tag="ClothDRAFT_1520" /note="catalytic triad; other site" /db_xref="CDD:48566" gene 72446..72727 /locus_tag="ClothDRAFT_1521" CDS 72446..72727 /locus_tag="ClothDRAFT_1521" /inference="protein motif:PFAM:PF01042" /note="PFAM: Endoribonuclease L-PSP; KEGG: mlo:mll4506 hypothetical protein" /codon_start=1 /transl_table=11 /product="Endoribonuclease L-PSP" /protein_id="ZP_05429660.1" /db_xref="GI:256004683" /db_xref="InterPro:IPR006175" /translation="MVGGDNFELQTKQALENIKIALASENATFNDVIKLNIYMVDGCD PAIGFKAFMETVGKLEKPPLITVLEVAGLANHLCLIEIDAIAVVEEKED" misc_feature <72446..72703 /locus_tag="ClothDRAFT_1521" /note="YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448" /db_xref="CDD:100004" misc_feature order(72536..72538,72542..72547,72551..72553,72557..72559, 72590..72592,72599..72601,72629..72646,72650..72655, 72686..72688,72692..72694,72698..72700) /locus_tag="ClothDRAFT_1521" /note="homotrimer interaction site; other site" /db_xref="CDD:100004" misc_feature order(72578..72580,72590..72592,72635..72637,72686..72688) /locus_tag="ClothDRAFT_1521" /note="putative active site; other site" /db_xref="CDD:100004" gene 72839..73186 /locus_tag="ClothDRAFT_1522" CDS 72839..73186 /locus_tag="ClothDRAFT_1522" /inference="protein motif:PFAM:PF05973" /note="PFAM: protein of unknown function DUF891; KEGG: cak:Caul_5448 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF891" /protein_id="ZP_05429661.1" /db_xref="GI:256004684" /db_xref="InterPro:IPR009241" /translation="MNVYHYETSGGKDLILEYIDGLPKNEKAEGLTILEKLEKEGLEA LEVLNTRQLRGKLWEIKFYRSNRIMYVVADEDNIYLVHACKKQKGKAEKFELDTAIKR VKELEKELGKKFI" misc_feature <73001..73150 /locus_tag="ClothDRAFT_1522" /note="Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470" /db_xref="CDD:163984" gene 73212..73526 /locus_tag="ClothDRAFT_1523" CDS 73212..73526 /locus_tag="ClothDRAFT_1523" /inference="protein motif:PFAM:PF01381" /note="PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ccv:CCV52592_0928 DNA polymerase III delta prime subunit" /codon_start=1 /transl_table=11 /product="transcriptional regulator, XRE family" /protein_id="ZP_05429662.1" /db_xref="GI:256004685" /db_xref="InterPro:IPR001387" /translation="MPFKKVNVKDEINKRLENDAELKKAYDCAQLEYEVLKQLVKMRK EMGFSQSDVAKKSGLTQQMVSRIETVGNSPTLRNFIKYVDSLGLEIKLEKKNTDVEYS KM" misc_feature 73320..73481 /locus_tag="ClothDRAFT_1523" /note="Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093" /db_xref="CDD:28977" misc_feature order(73329..73331,73341..73343,73416..73418) /locus_tag="ClothDRAFT_1523" /note="non-specific DNA binding site; other site" /db_xref="CDD:28977" misc_feature order(73338..73340,73413..73415) /locus_tag="ClothDRAFT_1523" /note="salt bridge; other site" /db_xref="CDD:28977" misc_feature order(73359..73364,73395..73397,73404..73406,73416..73421) /locus_tag="ClothDRAFT_1523" /note="sequence-specific DNA binding site; other site" /db_xref="CDD:28977" ORIGIN 1 ccgggcttaa tagaaaaaca gttagcagat atcttgatga aaactttaat ccggtccatg 61 ctgcctatgg caaaaagaga aatgggaagc tgacaccata tataaaagcg attgacgaat 121 accttgagaa agggattatg ggttcatata ttgaggagaa gatacgcgaa atgggatatg 181 agggttcatc atcaactgtg cgggattata taacagactg gaagaagcgg agaaaaaata 241 ttacgataaa agtaggaaag atgggacaaa aacagaaaca ataaaaagag aaaatatatt 301 aaagctattg taccaaccaa tagaaaaagt aaaaataatt agtaagaaac aatttgaaat 361 gatatgcaaa gaatatccgt tttttgaaaa gatatataaa ataacatggg aatttaagag 421 tatgctaact gataaaaata ttgatgcttt ggataaatgg atggagggag ccaaaaatct 481 aaacataccg gagataaaca gttttataaa tgtgattgaa cgagatatgg aggctgtaag 541 gaatgcgata aaatatgaat atagtaatgg gcttgtagaa gggtacatta ataaactgaa 601 ggtaataaaa cgaattatgt atggccgttg tagttttgaa acactaaaaa ccaaaattct 661 cggctcgaaa aaatgaggtt attcaactaa cattggaaag aactaatttt agagtagcat 721 taacaataag gcttaaaacg tttgccgatt cagttggcgc aatcaaaatt tgaggtggtt 781 aaatgtacaa gatactcatc gtggaagacg acaaagccct ctgcaataac ataaaagagg 841 gcatttccaa atggaacttt gaaggcattg ccgttcaaaa ttttgaggac atattaaaag 901 aatttgcaaa acacaatccc catctggtca taatggatat aaacctgcca tattttgacg 961 gattttactg gtgcaaaaag attagggata tatccaacgt tccggttata tttctttcct 1021 caagggatag caatatggat atcgtaatgg cggttaacat gggcggggat gattatgtaa 1081 ccaagccttt ttcaatggat gttttactgg caaaaatgca ggcacttatc aggaaagcct 1141 attcttacgg acagtttgac gggcagataa ttgaatgcaa tggagcaatt cttaatacta 1201 atgacggaac ccttacctat aatgggaaaa atatagagct taccaaaaat gaattcaaaa 1261 tacttcagct ccttatgaga aacaaaggga aaatagtatc cagggacaag attatgagag 1321 ttctttggga aagcgagtat ttcatcagcg aaaatacttt aacggtaaat gtaaacaggc 1381 ttagaagcaa attggaggac attggcttaa aagatttaat agtaactaaa aaatcacagg 1441 ggtatatgat accatgaatg tatttaagta tttaaaggac tcatacagac aaattgtatt 1501 tttcttactg attattttaa taacggattt ggtattaatc agcagtgtgg atttaaaaaa 1561 atcattattg gatattttct atttaaatat cctctttttc ttcgtcttcc taatcttttt 1621 ggccatagat tataccaaat ggagaaattc atacaaggat ttgaaaaggg ctttggatgc 1681 aagggaaaat atagacagtt ttataccaca gggaaacagg ctggaagaaa tattaataag 1741 ggatattatt gagttaaaga ataaagaaaa gctggaggag acagagaaac ttaaaaagaa 1801 tttggaagag ataaatgatt atataacaaa atgggttcat gaaatcaaaa tacccctgtc 1861 agtctgtgaa cttatagctg acaaattgga agatgaaggg caatatgacc tgtcaaagga 1921 gctgatacag gaaacggaaa gaatgaactt ccttgtcaat caagtgctcc atatgagcag 1981 agcctccagc tacagtcagg attttatagt ggaagaagtc aatttaagca gtctggttaa 2041 aaatgtggta aagaacaata tgaatttgtt tatatcgaaa aaaatagaac tggaaatggg 2101 taatctggat ttcaacatat ttaccgacaa aaaatgggcc tattatgtga tagaacagat 2161 agtcaacaat gcctgtaaat acgtagatgt ccatggaaaa ataaaaatac agggcgagga 2221 gaatgatgaa agcgtaatac tgactatatg ggacaatgga atgggaatac ctgaaaagga 2281 tatagacagg atttttgaca ggggatttac aggagaaaac ggcagaaaga ctacaaagtc 2341 cacgggcatg ggactttata tctgcaaaaa agtggcggac caattgaact tcaatattga 2401 agtatcctct gaggtatcga aatacactga attcaaaata atattttaca agctgtcgga 2461 ttatttaaag gtgacaaaaa tgtaacatta aaaactctat tgtcaccata agtgatggaa 2521 tgaagctttt gcagcaatta gaatataagt agaagaataa attctctctt ttatttagga 2581 gagaatttta ttatgaatcc ggaggagata gtatggaagc agtacttgaa gcaaagaacc 2641 tgaggaagga atatggttca aagggaatgg cttttacggc tttggacggt attgacttaa 2701 aagtatacaa aggggaattc ctgggaataa tgggtccgtc aggagcaggc aaaaccacct 2761 tgctaaatat cctgtctaca atcgacagac ctacatcagg caatattttt tatgatggca 2821 gggatgtttt aactatgaaa aacagggaac tttcattgtt cagaagaaac aagatcggat 2881 ttttgtttca ggacttcaat cttttggaca atatgtcggt tgaagataac atagcgttgc 2941 ccctcgcact ttcaaatgta aatgtaaagg aaataaaaga aaaggtggaa aagttaagtg 3001 agttctttgg attaaaggaa catcttaaga aataccctta tcagctgtca ggggggcaaa 3061 agcaaagagc ggccgcagcc agagcactta tcacatcgcc gtccatagtt tttgctgatg 3121 aacctacagg agcgttggat tccaaatctt cgcaggaatt attgcaatgc cttttgagga 3181 tgaatgagga attgaatgca actataataa tggttaccca tgatgctttt gcagccagtt 3241 actgcaaaag aattttatac ctgaaggatg gaaaaatcca tgcaagattg gataaagact 3301 cgaccagaaa agagttcttt aaaagaatta tcgactttgt cggaactatg ggaggtggcg 3361 tgggtgaact catttaaatt ggctgttatg agctttaaaa gaaatataaa aacttatgga 3421 atgtatctta tggcaatgat tttttcagta gccacctatt ataattttgc atctatgaga 3481 ttcaaccctc aattccggga ggcaaaagat ttaactgtat atgtacagag ctcatcagtg 3541 gttgcctccc tgcttatgat attgtttctg atatttttca ttatgtattc cggcaacttc 3601 tttctgaacc aaaggaaaaa ggaaatagca gtatatgctt tcatgggaat tgacaactat 3661 aaaattgcct ttatgtttgc atcggaagga ttgttgatgg ggataatgtc tttggtaatc 3721 ggcctgtcgc ttggaattct gttcagcaaa ttgtttctga tgttgcttgc aaaggtagct 3781 ttactgaata tgagaattaa tttcttcata tcagtaaagg ctattgtaga gactgtagtt 3841 gcatatttgg tcattttatt tattacattc ctgaaaggat atatagatgt tgtcaggaca 3901 aatttgattg atttgataaa tacgttgaaa aaatcagagg agcttcctaa aattaattat 3961 ttaaaaggca ttgcctcatt aatggttata ggtgctgcat attatattgc ggtaaattat 4021 ggcaagttcg ggtttggaaa agccctctta tggacagtga ttctggtcat tataggaacc 4081 tactggctgt ttggttctct tttatcaatg attatcaggt acttcataag cagaaaaaag 4141 tttttgtata aaggcacaaa tattataagc ttttcaaata tagcctttag gataaagggc 4201 aactataggg cccttgcagc agtagcggta tcgataactg tgtgtataac atcctttggt 4261 acggttagct ctcttaagta ttttgtaaat gagaaccata agattgaggt accatatact 4321 gttacctata tttccgaaaa acaggaagaa atagaaagag tggatgaaat aataggaaaa 4381 tcgaatcata acgttaagtt gaaagaaaag gccaactttt tgtttgtccc tgattcacag 4441 gttgtagtgg tgaaactgtc cacttttcaa aggatactga cggatcttaa tgttaaaggg 4501 cgggataaaa ttttatctaa aattggacag ctgaaggaag aggcggtata tgtagagaga 4561 cccggagtct ttatgagcct gttggaaaaa aatgatataa aaataggtga cagggtctac 4621 agaataaaag ctcagacaaa ggttcctttg tttggaagcg gattgccttt tccctgtgtt 4681 gttgtcggcg aggaagaata tgaaacatta aagtctgaat ttgaagagaa acagtttaat 4741 ggaattatac ttgacaatcc ggaagacaca agggatttaa ctttgcagct ggcccaaata 4801 ctgccggaga attcaagact atacacctat tttatagccg gcgctgcaat gtatgactta 4861 attgggatag tatattttct tggagctttc ctgtttttag tgtttgtatt tgccacaggc 4921 agcataatat actttaagat attgagcgaa tctttcagag ataaagataa atacgaaatt 4981 cttaagaaac tggggacaac ggatgttgaa atcaaaaagt ccgtatcaaa acaggtgggt 5041 gtgtttttcc tgttgccgct gatagtgggg ataatccaca gcacagttgc catttcagta 5101 ttaagtgacc ttatgagtta tagtttgaca ttgccgacaa ttataagtat tggcgtattt 5161 ataattgtat atgcgatatt ctatgtcttt accggaagaa aatatgttaa tgttgtaaga 5221 aatcaggctt gaattaccga atcaagcctg attttttgga tgatatgttc ttttttcact 5281 caaaacgtcc ggcttaaatc attatatgag acggtatgta aagttgtaac tgttaaaaaa 5341 gctccagtgt tttttgcttt tgggctacat aaaaaattta cattttatta tatagataaa 5401 atcgatatat gccgatacat attaaagcat gcataatttt gctaatagaa ataccaataa 5461 aaggagagga ttaaattgag taaacgtttt tcatcagctg taatagccat ggtagtttta 5521 tttgtacttg ctacaacatc ctttgcagcc acaactgaaa cattttatgg aggctatagt 5581 aatgtagcta ctaaaggaag cattgtagtt gagctgacaa acatctcttc aaagaaaaat 5641 gtaatattaa gcgaaacgga agcagaagtg tattttgatg atcctactga gactcttaac 5701 atggtagtgg cttatgatta tgatgaagat gaggagataa ctgttagaga tattttggaa 5761 tattacaaca ataatggcgg tgttcctaca tactatgcag atactgcacc tgtagttgtt 5821 actgccaaaa ctgcattgag taccttctat ttttgctata agggagatat tccggcaacc 5881 tatgaaccta aattctactc ctttgaagaa tatgtttatg attttgaaaa taaacagact 5941 tataccgagc ccccggaaga ttggctgctt gctgatggta cttctgctac tttgagcgaa 6001 ccgggcaaat acttttttat ttttgtagat gatggacttg tttcttcttc cttcccgggt 6061 attttttgct tacatatagg tgatactccg tctgaaactc cggttcctgt ggaattaacc 6121 aagataaccg taaacccgac aacttcaaag gtattggtaa acggcaaaat tgttgaattc 6181 gaagcttaca acatcaacgg ctacaactat ttcaagctga gagatttggc acaggctgtt 6241 aacaatacag agaagaattt tgaagttacc tgggatgcgg caaacaatgc aatcaaccta 6301 atctcaaaca aaccttacac tccatcaggc ggcgagctgg ccaagggtga tggtaaagcc 6361 aaagttgcaa ttccgaccac ttcaaagatt tacaaagatg gcagggaaat attcctgacg 6421 gcttataaca tcaacggcaa caactatttc aagctgagag acgtggccaa aacctttgat 6481 attggtgtaa cctgggacgg cgcgactaat acaatcggta ttgacacgag cataagttat 6541 gtagaataaa agtggaattg aagagccatt acttccgtgg ttacacggaa gtaatggctt 6601 ctattttttt gcagaccgct ttcattctaa gttctgagtc gatttcgata tccttggaca 6661 tcgggtgtat tggctttcct atatgaagac gcataaccgg cttttttcgt atgattttta 6721 tcagtccttt tggaggttca aaggtgatta acatagggac aattggcact tgagcctgtg 6781 ccgcaagata aaatgcccct tttttgaagt tttgcaaacc ggtatcatag ggtcttaatt 6841 ccccttcggg aaaaaaatgc acgatacagt ttttcatcaa aagaaactcc atctcgtcaa 6901 aaaaggcttt gagctccata atattatcag gtatggcaaa cccgccaagt attcgcacaa 6961 gcttgcccgg ccagagcgtt tttacgttct gggtgagtgt gggaaaaaca accctgcgtg 7021 ggaaaaacgt tacgccaatt aaagcgctgt ccagcaggtg gacatggttg cataccgtaa 7081 ccccactttt gaggccacgg atattttccc tgccatagac tttggcacct aaaacaaaac 7141 gtgtccacag cagcaggatg ggacaggcta ttacaatttg gaacaagcgg gtggatagtc 7201 tgaaaaaaat actgcgatgg tattcatttt tatgattttt tgtcatggat gaatatactt 7261 tttctatttt tctgatactg tgttccaggg cgtattgctt tcctaattga gcatatttct 7321 tttcagcttc tttcagctgt tccggatggt ccagccagta atcgattttt tccgccaatg 7381 attcagggga ccctgctttg aaaagattct ggggaccgag cgcaaactgc gccgcggcac 7441 tctgtttgct gtcggagatt atcggaacca gcccgcatgc gaacgcctca attaatgaga 7501 tgccttcaat ttccgcatct gaggcgtgta catacaagtc gcattcgtgt atgagcttaa 7561 tcagctcgtc acgattgtaa tacccaaaca caggaggatt ggggagtttg tttccaagat 7621 ggcaaagttt cttctcccag gggccgcttc cggcaaaata cagctgaata cgatcggcat 7681 aacgggattt catgacggca cgaatcagaa catcctgcct tttttcggga gaaagcctgc 7741 caatcataag tatcttaatt ggtttgaaag tatgttccct gggctttgcg ggagcacaaa 7801 atgccggatg gacgccgttt gagatgacgt gcaaccgtgc tttgtatccg tggctcctga 7861 gctgcgcggc aataaatttt gacgggcagt ggatatgtga aaatctgcga tagaaaaaca 7921 ggtagaacaa aaaatatgtc aaatgggcag ccggagaaaa ccgcttaaga cctatattga 7981 aggtaatgtt ttcaggttgt atgtgaaagg ctgcgattgc agggatgttc atttgcctgg 8041 caactctttg ggctgcgctt ccgagcggcc agggttgata tatatgcaca acatcggacc 8101 ctgaaattgc ttttttcaaa gtggagcgaa ccggctttgc aaacagtgta ttctgcttgt 8161 gggccagcct gcttgcaatg gggattttga gttccggcag ataaaacatt tcgaaaccgg 8221 tatcagggtc tttgccgctt tttaaaggat caccgcatgt aattatgcgg atttggtggc 8281 cgcgttgtga cagtgcctcg gcaaaacgca ttgcagaaat ggtggtcccg ttgttgttta 8341 tgttaaaggt gtcatttacc agtgtaataa ccatcagaaa tttgactcct ctctcttttc 8401 ttgccgcatt tacttttaat ttttcaaata caaaaaagaa aaccgtcaac aaaaataaca 8461 cactgtgaac atctttatac cgcctttata atttttattt tagcagaaaa attatcaaga 8521 gcaacgcaat actttttcca tttttgagct ttatcagttc attttaaggt ttgttttatt 8581 tgtgctgttt gcagagtaaa atccatcgta atataattga aaatgcaaga ttaagttggg 8641 aggtataaat atgaaatata ttgtggctgt taacgcgagc ccgcgcagtg gttggaacac 8701 aagccaactg gtagaggcgg ctgcaaaagg agcaaaagaa gcaggagcaa ctgtggatat 8761 tattgatctt tacaagctgg agccttttca agggtgtatt tcctgttttg gatgtaaact 8821 tcccaggaca ttcgggagat gcgtatcaaa agacggtttg tcggaagtgt tggataaaat 8881 tcgtaaagct gacggactta ttcttggttc gccgaattat ctggggaatt tgacggcagg 8941 attcagggca ctttatgagc ggctgatttt tcagtcctta acttacaata aggaacggcc 9001 caattgtaat gaacatatga ttccggttct gcttatcaca acaagtaatt gtgatgaaag 9061 tatttatgac aagataggtt atacatccat gttagaaggc tataaacaga tgttggagcg 9121 ttttgtcggg ccgacaaaaa tcatgatctg cggaaatact ttgcaggtgg atgattatag 9181 caaatacaat tggactattt ttgacccggc gcagaaaaag gcccatcatg aagcggtgtt 9241 tccgctgaaa ctgaaagaag catatgaact tggagcaagg cttgtttaac tgttttggga 9301 agaagacgat tttttgattt tgtgtgaaat gtgacggaaa aggaataaag tttgacgcta 9361 ttctatacaa aagatactaa tattgaaaat ataatcaatt tattgttata attatttatt 9421 atgttataaa ggagggagat gttaaaaatg gttaaaataa agctgatttt aataacaata 9481 ataatttgtg gagtgttttt gttggcaggt tgcggcgata atggaaacgg aagcagtcag 9541 ccttccggtg tgtcaaattc gttacagaat atacaagggg cagaaaataa aaaagaaaag 9601 actaatgccg agaaattttt ggaatatgct ataaaggctg ctgatttaag gaattttacc 9661 gagactggca attatgcagg aattggaatt acattacagg atttgtacaa ggaagatatt 9721 ataaatcctt atactggagg aacttcttta actgtaatga acagaactag agatatgatg 9781 aaagatcagc atttatccag aacaagattg tttagtgtag actgtgtaat aatagatgat 9841 tatatgacac aacttaaaaa ataaatacag acgaagtagt ttattgtgta aatccagaaa 9901 gcaagggcat ggtatttgca ttttggttaa ttgatggtgt atatatatat gaggttgatg 9961 aaaacggtca aaagataaat gaaattaagc atttctttga aaaagaagaa taaagctttt 10021 atgcatataa atcaagcaaa aactcatatg gagggcttga agtgaagata atttcaaaaa 10081 tattaacatt ggtattgata gttacgtact tgttatcatt gccaacatca gcagctgagc 10141 tcccaattcg agtggtagta aatggcacaa acataaattt tcctgatgca gagccgttca 10201 ttgacgagaa ttcaaggaca caggtaccaa tcagattcgt tggagaagct ttaggtgcgg 10261 atgtgagttg ggatgggaat acgaaaaaag tgacaataac attgaacgga agaaaagtag 10321 tacttcagat agggaataag acgtatgaag taaacggaca gcaaaagcaa atggataccg 10381 tggcattatt aaaagagtcc agaacttttg tccctgtgag gtttgtgagt gaagccttag 10441 gtgcaactgt aaagtggaat gcaaatataa gaacagttta tattgacatg aatggtgatg 10501 cagcaccttc tcctggaccg acaggagaga cggtaaaata ctatgacgga atagcattta 10561 atgatgttac agatgttgac cagtatggca gaataaaggt cgagaaatta aaggagtttt 10621 tgctcaagtt agcagaccaa ttgagatttg tgaaagaaaa cggaaagtac tatattgaat 10681 gcacttatcc agataaaccg gaagggtacg agtggaactt aataataaga atttataata 10741 aagacaattc atatgaagca tatactccaa ctactcgtgt tcctgactgc caaataccta 10801 cagaaggctc gtttaaaaaa gaagcaacag ttattaaaga tataaataat attagtttct 10861 ttaatgttac tatttcgtta gaacatccta aaacaggcag tttaggcaga ttaaatatag 10921 tttattctac agataaatca gatatttggg caacttttgt tcctaagtca gggacgatac 10981 cttcagaaga atatgaaacg tttaattttg acaaaatgtt tcgatggtaa ctaaattaga 11041 ggtaaagaat gagtaaaaga atttgatgga tattaatgat tgtaataata acttggttat 11101 aaaatctttg aagaatttga tagaggagta atttcatatt tgcatcctga aagttcgtac 11161 aaatttaaca ctgcagggtt aatcatccat cgatgaggta atgaataaaa gccctgtttt 11221 aagaaattta gtaattgaat tacaacagag cgacaaatgg aatgttaatg ctgttaggaa 11281 tttgactaag tggaagaaag tgctcgaatt gaccactgaa atcagaaaat atgcgaaagg 11341 attattattc tttataaaga gtattaacat aaaaatataa ttttataaag gagaagatga 11401 tattgaaaat ggttagagta aaattaatgt tagtagcagc gatagtatgt gtgatatctt 11461 tattatctgc ttgcagtggc aatggagagg gaaataatca gccttctggt acaccgataa 11521 aaagtttgac ccagagtacg cagaagacac aagataaaaa agaaaagact aatgcagaga 11581 aatttttgga atatgctata aaggctgctg atttaaggaa ttttacgaaa acgggtaatt 11641 acgcaggagt tataaaaacg ttgcgtgata tatatgaaga tgatattgta aatccttaca 11701 ctggagctac ttcaatatat gcgatgaata ggacaatatc ttatattgat aataacgata 11761 tgtccgtgac cagggggtac agtgttgatt gtgtagtaat agatgattat atgacacagc 11821 taaaagattt agatacatct gaagtagttt attgtgtaaa tcccgagagt aaaggtatgg 11881 tatttgcatt ttggtttatg gacggtgtat acatatatga aatagatgaa aacggccaaa 11941 agataaatga aatcaagcat ttctttgaaa aagaagaata aaaattttgt ataaaatata 12001 ggaggaaaag tatgggagat tcctggagcg gagtaagaaa aaggttggaa caggatttgt 12061 tgtgtgatgc ccttaaaggg agattaaaat attttattac aaagtataac aatgctcacg 12121 acgaatcggg cagggtagcg attattgttg atggcagaga aataattcaa ggcgatatct 12181 ttagatatta taaaggctat agagaggtag agaaaaaaat aaaaagtgaa ttgggtattc 12241 ccaaaagatt ttgggacggt aaaaggattg taaatgatga ggtaaacaga gaggccgaag 12301 agtatattga taaaataaga cttaatgagg gaatttttga tgtatggcag tttactgatg 12361 ctgtggaaag atttttgaat tcaaatatta aggaaagttt agtttccgaa aatcctcttg 12421 tccgcttgtt agccatagtc gacagaagag tggggaaacg aactttggaa aaattaaagg 12481 acactgtatt gcaacaaccc gaatggctcc aatattttta caggctaaga cttcaggctg 12541 aatctataat ataaattgac tctgtaatta tacaacctga aaaatataaa actttaaata 12601 gtccgtctcc ggaacattcc acaggatggg atggtccggg gcctgctgac gggcttcaat 12661 ctgccttaag gatacggaag catcctttgc ggcgcttgcc agtgttttgc ggaacaagtc 12721 atccgtcatg aaatgactgc agctgcaagt agccagatat ccgccgcggg gcagcagttt 12781 catggctttg aggttaattt ctttatatcc gcgggcggca gactgcaccg tcttgcggga 12841 tttggtaaaa gccggcgggt caagaatgat ataatcatag tcatggcatt tttgttctgc 12901 cagttttgtg agcaaatcaa aaacatcttc acagacaaaa tccatttttc cgtccagacc 12961 gttgcgtacg gcatttgctt ttgccatgtc tatggctgac tgtgagatgt caacacaggt 13021 cacatgctcg gctcccccca gggctgcatt aaggccgaag gagccggtat gggtaaagca 13081 atccaataca cgcttgccat tggcaatccg ggccacagcg gcgcggttat acttctggtc 13141 caggaaaaag cctgttttct gcccgttttc cacatctacc agatacctta caccgttttc 13201 gcatatctcc gtaacggcgg attccggtgc cggtatgcca tcgaacaggt accagccttt 13261 atattccggc agtccttccc gtgtacgcag ggcaatgtca ttgcgttcat aaatacctgt 13321 gatggtttca tccatttcgg taagcacatc ccagagagcg cggtaaaccg tatccttgac 13381 aagttccatg ccaagacagg taatttgtac ggacaaaagg cttccatagc ggtccactgt 13441 cagacccggc atatggtcag cctcaccgtg aatcaggcgg caacaggcaa agtctgcacc 13501 gggtatgacg gttttccggt agcgaacggc atattccacc cggcggcgcc aaaagcgggc 13561 gtcaaataca tcattggcgt tgcgtgaaat aagtcgaacg gtaatcttgc tgacactatt 13621 gtaaaaacct gtccccataa aggcgtttcc ggcaaacaca tccaccagac cgccgttttg 13681 gagttcgccc tctgttttga gaatttcttc tccgtatatc catggatgtc cgtcttttac 13741 gctgcgctcc gccttacggg atatcataat tttgggatac tgccgttgct gtttcatccg 13801 tgtcaccttt taaaatagat tttttccttg ctgattgtaa catatttccc tttcgccttc 13861 aacatttgca atactcaaca aaggtgctgt gtaacattga tgtcaaggtt gtattttttc 13921 cgtcagagtc gagctcgaaa actaatattt tactctgaca cccagctgtt ccaatttctt 13981 tattgtatca tcttttttag ttttaatcgg atttccggct atattgatat catagtccaa 14041 acccttgtat ttaaaattga atgcaccgtt ttccgcaagc tctacgaaca ctgaaatatc 14101 atctatttga ttattctcca aattaacatt gtttagctgt gtcagttcct taagaaaaga 14161 gatatctttg attttattat tttctaattt aagcgattcg atatttatta agttttggat 14221 gggagaaata tctctgattt tattattgga taaatacaat gtttccagtg aagacaactg 14281 tgaaaccggg gttatttcag taatcttgtt gctgtctgca tataaacttc tcaggttttt 14341 catattttca atgccttcaa ggcttgatat attattgttt tcaagtgtaa ttgtttctaa 14401 atttaccaaa ttccttaaag gttttaggct tttaacctga ctggaatgaa tgtaaagcct 14461 ttttaggctg acacagttgg atagaggaga taaatcctta atgttattgt ggcctaaaaa 14521 caaatccagt aatttttcaa ggttggataa aggttttagg tcctcaatct cgttatttgt 14581 aacatcaagt tcctcaaggt taattgcata ttgaagacct tcaatactct taattttgga 14641 tgaggatgct tccagtgcgg ttaggctttc cagatgattt tgtgtcaatt ctatatcttc 14701 gcttaaatcc aattgattac gaattgcttc ttcaaggcgc ttgtcttcaa tgagtgaata 14761 gctgttattg gtattcgaag accctgtggt cctgttggag tatgcacaag aatttaaaag 14821 aaaagacaat aataaaagta atattataat gccttgtttt ttcatgataa cctccgttta 14881 attaatagta cttgccggtc tgagtgtcta ttatcttttg cataatgatt taccgtaata 14941 tttctgcctg atgcgtttca aatattgttc ataagtcatt gggattgatt attttactta 15001 ttttttaatc atcagtataa aagatgtttt tttcggtttc aagagctttt tcgattataa 15061 gatgtatcca ggcagaaaat ttcaaattag gaaaatggaa aagttatcct gttgtaaatt 15121 ttcctgcaaa aatattgaaa gtatttgctt ttttgcggat aatggaaata gaaaagatat 15181 ttatattccc accaaaaaaa gaatgttggc ggcatcggga acatgtatat gcacgacatt 15241 ttattcaagg cacgcttgca tccccaaaag aaaatatcgg aaatggatga cgatagtttc 15301 aataaaaacg ggcagtacat cttcttttat atgccccgaa tgccaaagat tacaaaatga 15361 gattgggtaa atatttttaa tacatggaat ggtggatgat atgaacacaa acattgttta 15421 tccggattac agcaattcaa tagcgaatct tgcaaattca attctgaaaa aatggggact 15481 tccgactaat ggtaaaactc tagagcttct ggaccggtat cttgcgaaag attataagaa 15541 tgtggtggtt attcttcttg atggaatggg cagatgcatt attgagcgca atctcgaaaa 15601 agacggcttt ttcaataccc acttggcggg aacatacagc tcgacatttc catcaactac 15661 agtagcggct acaacatcaa tcgatagcgg tcttactccc tgtgaacatg gatggcttgg 15721 atgggactgt tactttcctc agatagaccg gaatgtaacg gtatttctta atacggacac 15781 cgagaccgga gagaaggtgg cagaggagag tgttgcatgg aagtactgct ggtattcaag 15841 cgtgattaac aggattgatt cagcgggagg aaaagcatat tatgctatac cgtttgtttc 15901 gccttatccg gcaacatttg aggaaagatg cgaactgata aaaaaatatt gtgatgaacc 15961 cgggcaaaag tatatctact gttattgtga cgaacctgac aaaactatgc atctgaccgg 16021 ttgctacagt gaagaatcaa ggaaagtgat ttcatggctt gaaagaaaaa taaagagtct 16081 tactaccgaa ctaagggaca ctcttgtgat aataactgcc gaccatggcc atgtgaacac 16141 aaaacgtgtg tgtattaagg attatccaaa tattatgaat tgtctgaaaa gaattcccac 16201 tattgaaccc agagctttga atttgtttgt gaaggaagac agaagagacg aatttgagaa 16261 agaatttact tgtgaatttg gcggcaagtt tctccttttg ccaaaagaaa aagtactcga 16321 aatgaaatta ttcggatacg gaacagagca taaagacttt cgcaatatgc tgggagatta 16381 tcttgctgtt gcaacagatg atttgtctat ttttaacaca aaagaaaaga aagagaaatt 16441 cgttagctct catgggggac ttacagaaga cgagatgatt attccgttga ttattgtgga 16501 aaagaaatag gaaggttcca aaatggatgt actcggcctt aaaggaaaga aaacaaagga 16561 tgatgccgaa aaatttgttt tacaatatat taaaaattca ggcttgtata tggtattata 16621 tacttgtcag taactgctga atgcaggaaa gaaaggggaa atgtttatga cggcattata 16681 tgaggtgatt gtggcttaaa actgaatagc ggcatggcaa aaattccctt gagattttgt 16741 gtttggcgtt acatacacct ttcttttgct gtgcctttct aaaagtgaag gtaacccttc 16801 gagaatactg taaatatcgt agcacatcga agaggtgtgc tttttgcata tttgtctaca 16861 aaccgcagag tttaaagttc ttccgaaggc tactttctgc ggtattttta tgtctttttt 16921 gcgtttatct tacacactta acaatatgtc aataacggag ggattaagaa ttgaatttga 16981 tagattacgg atttgttccg acaatgatgt cggaagatgt cagtggtttt cctgcgagaa 17041 ttaccgcagt gcataaggaa agatatgaac tggtttgtga atatggatat acatttggaa 17101 gactaaaaac aagcatatat tatgccggtg gatttgaaga ttttccgacg gccggtgatt 17161 ttgtactcat agattacaat ccagatggtg acagccggat tgtaaagacc cttaaaagga 17221 aatctttctt ttcaaggcgc aatcccacgc ccgggaaggg agaacaagca gttgccgcaa 17281 actttgacta tgtgtttgtc atgcaatcgc ttaaccatga ttttaacctc aggcgtatgg 17341 aacgctatgt tactttgacg tggcagtccg gagcggtgcc cgtgattgta ttgacaaaag 17401 ccgacttggt agaggattgt tctgaacaag ttttggcatc gcaaaaggtt gctccgggag 17461 tcgaagtaca tgcaataagc acaataaccg gttttgggct ggatgtgctg aaagattact 17521 taaagccctg caaaacggtt gtttttcttg gttcatccgg tgttggcaaa tcaagtcttg 17581 tcaatgctct tgcaggacaa gagattatgg ctgtgggtga tattcgtgaa gatgattcga 17641 aaggccgcca cacaaccact catcggcagc ttattatgct gccgggcgga gccatgatta 17701 ttgacacacc cggcatgcgc gagcttggca tgttggatga tgtaagcgtt ggccttggtg 17761 aaacattcag tgatgtggtg agttatttgg gacggtgtaa gtttagcgat tgcaggcatc 17821 aaaccgagcc gggctgcgta gttcgggcgg cgattgagag aggtgagctt ccgaaagaac 17881 gctgggaaag ttatttgaag cttaagcggg aagcaaactt ttcggatgac aaggaaggat 17941 atttgcgtca aaaacagcaa tggagtaaag agattgccaa atggagcaag aaaatgaaaa 18001 agaatggggg aatcaggaaa tgaacaatta tacagtaaga cagataaaga ctgatgaata 18061 cgaaactgta agacagttgg acagtgatgc ttttagatat aatgaatttg gagacgactg 18121 agagtttcac agaatttttg ctgacaatat ccggaagtcg ccatatttca taccggagct 18181 tgatttggtt gcagttacca atgaaggttt tattcttggg cacggtattt tttcggcgct 18241 tcccatgggc aatgacgcaa atcatgtcat atggctcaac agtctggctg tgaggcatgg 18301 ggaaaaagat aatcatgccg aaaaaagata cgagtaccag cgaaagggca ttggcacagc 18361 cattgtgaaa cacgggcttg aaattgcaaa atcccttggt tttacggctt gtatgacatg 18421 tggaaatcct gatgtgtata aaaggaaaat ggggttaaag aattaccgtg agcttgggat 18481 taagaaggac gacagtgtag aggatgctga tgaatgcata tttgcaattg aacttgttcc 18541 gaatgggttt gatggcacga acaggattct tagcttttct tattatgatt tttttcaaat 18601 gtgaaaaata aaacctgggc ataagcaaaa aggcagggga catagaactc ggaaccgtcc 18661 cctgcctcat attttaaaca tcaactccaa ggaacagcct gacgaaatgc ccgattatga 18721 aggaaataac tgccactccc aaactgatgc cggccatttc aaagaatctc tgtttaaagg 18781 gaagatcctt ggctactgat atataaaaat tgaaaacaag tattattaat attgccataa 18841 taattgtaag caccagactt agcacatagt tggaaaataa aaggtaggga aataccaggc 18901 atgcaacggt gaaaacatat gctcctccgg tatataatga tgatttaagg gcacggctgc 18961 tctcctgctc tgttctggct gaaagatatt cggatgccgc cattgaaagg gtggccgcta 19021 tacctgttat aaggcctgaa agtgctatga ggcgcgtatt ctttaatgca aatgtgaggc 19081 ctgccagggt gccggtaagc tccaccaggg cgtcatttaa gcccaggacc attgaaccta 19141 caaattgaag cttttcctcc tcgattattt caatcagttc ttcttcatgt ttgttttctt 19201 cttttgctat tgttttaaat tcctcaattt tattcccaag ttccctgtat agtttttcag 19261 cgccgctttc ccctttttcc atgagcttta taccaaaagt aatgccaaat atcaatgaaa 19321 tgaaggtata aaagtatatt ttcaaaatat ttggcttcat atccgttcct gtaaactttt 19381 ttaactcgtt atggtgggat agttcgtcct gggcgatttg tttaagaact ttgctgttgt 19441 gttcattttt tatgaatgag gatagttttg aataaatgtg gtactctgtg atttcatttt 19501 tttgagcttt tttcaaagat tcaattgtat cagcgtctat tttgtaattc aactcattca 19561 ctccttttat ttatatggaa atttgcgatt atgcctcttg ttggtttgga tatttgaatt 19621 cttcattaat ataacataaa aaataaaaaa gagcaaaatg aaattagcca atgataggct 19681 gtgtgaatgg gttgtatgga actatgtttt atcgtttatg aatttgggat aaattgtcaa 19741 cttcatatat tgattttatt tgatttttgg aataaagtat aattgtgttg agttagtttt 19801 tcattatgtc taaaagggct gcgcaaaaat aaggatttca gaacgtcgta ctcaggcttt 19861 atgcaatgat ggcagaatac caagtgtaaa attgcatggg tgaacagagt tataacggca 19921 gatggtgaaa aacttgaaga tacacgtgaa taaaaaatgg aaatacgaag ggagataaga 19981 aattggaatt tgcaattagc attaataata ttaattctac tgtatgcgca aaaccttttg 20041 taaagtgggc cggaggaaaa gggcaattgc ttgacacttt tagacaatat tatccttcta 20101 cgcttattaa aggctatata agacgttata ttgagccttt tgtcggcggt ggggcggttt 20161 tatttgaaat tttgcagaaa tataaagttg aggaagcttt tatatttgat ataaatgagg 20221 acttaattaa cacttatgta gtgattaaaa atgatgtgca caacctcgtg gaatatcttt 20281 cagatttaga gtgcaagtat ttaaatttgg atgaaaaatc tcgcaaagac atgtattatg 20341 atataagaga tgcatacaat tcacgagctt taaagaacaa tcagccggat gttgaaagag 20401 ctgcacagtt tatttttcta aatcgtacat gttttaacgg gctttatcgt gttaatcgtg 20461 cgggacattt taatgtgccg tccggagatt ataaaaatcc aaccatttgt gatgagaaga 20521 atttgtatgc agtaagttct ttgcttcaaa gggtgcatat atttgtcggt gattatagag 20581 aatgtgccgg atatgtagac aaggatagtt ttgtttattt tgaccctccg tacaggccgc 20641 ttaatgttac atccagtttt acatcttata gtaaatttga ttttacggat gaagatcaaa 20701 tacagctggc aaaattcttt tcagaaatga atgatacagg tgctttgctt atgctgagca 20761 attccgaccc taaaaatgaa aaccctgatg ataatttttt tgatgaattg tataaggagt 20821 ttttcattca caggataaag gctaagcggg cgattaattc aaacggcagt cggagaggat 20881 taattagtga acttcttgtt acgaactatg aagtaaaaga ctaggaggat cacatgaaat 20941 attcagaaat atttaaaaaa cggcttgggt gtaagaacac agatgaagtg tttaattatt 21001 tgctttctca catgaaggag actattaaag gatgggactt ttttgttgcc tgggaaaaag 21061 taatgaacaa ggtggggagc gttgaggttg tattaaatat attgaactac cttgtaggca 21121 aggaaaacgt agtggaagaa tttaaaatgt tgttgggcag gtatcccgaa atagctgagg 21181 ttcttccggc cttgctggct ttaagggaga aaagtattaa agttgttgag cctcttgcgg 21241 ataatgtttt taattacaaa gaatatgtgt ttcgtaaaaa gaagaaatat aatcctgaag 21301 aaatagaaat gctggcagag ttcgctgaaa aaaccgggct tcttgccatg tttgaaaaga 21361 aaaacataaa aagtgttgtt gattatgcaa ttggtgttga agtaggcctt gataccaatg 21421 ccaggaaaaa tcgtagcggt acggccatgg agatgataac cgagctgttt gtcaaaaaaa 21481 tttgttctat gaataattac cggtatcttt ctcaagctac ctcgcacaaa attaaaacat 21541 cttttggata taatgtttct gtggacaaat cggaacgttc gtttgatttt gcaatagaca 21601 acggtcataa actgtatctt gttgaaacaa attattacgg tggcggcggt tcgaaactaa 21661 agtccgtagc cggagagttt acgaccctgt ttagctttat caaaaaagag acaccggaac 21721 atggctttat ttggatcaca gacggtaaag gctgggaaac tgcaaaaaaa cctttgaggg 21781 agtcgtttga caaagtagat tacgtactaa accttgacat ggtgcaaaag ggcattctcg 21841 aggatatcat atcgcaaggg ttgtgagact atgggaagaa aagtcaagtg cttgtattgc 21901 ggagaagaat ataccagaac gcagtatcct gaacatcttg aaaagaacca taaagatggg 21961 tatttcaggc tgatcgaaaa aataaaaagt gatattgaga gtgatttcag tattaaagat 22021 acagcagcca ataatgatgt aacttgtgca tttgtcaaaa aagttgcaaa agaatcaaca 22081 atatgcctcg aagagaaatc aaaaagttat tttgcggaca agcttaatat taaatcgtgg 22141 gagcctgaaa atttcaatct tgaaacaact actgtatgga gctttcctga caggggagac 22201 tgggctactc acagcggaaa atacagaggt aattggtcac cttttattcc caggaatgtt 22261 attttgcgat attcaaaaga aggagaaact gtgctcgacc aatttgtagg tagtggaacg 22321 acgcttgttg aagcaaaact tttaaagaga aaaggtatag gtgttgatat aaaccctgaa 22381 gcagtaaatt taacttgtcg taatataaac tttgaaaaag aagattgcgg agaaacagaa 22441 gtacatgttg gagatgccag gcatcttgga tttattaaag atgagagtat agatcttata 22501 tgcacccatc cgccttacag taatatcatt aagtacagtg aagacataga gggagatctt 22561 tcccattgtg atatcaatga gtttcttgta gaaatggaaa aagtcgcaaa agagagctac 22621 agggtgctca aaaaaggtag attctgtgca attcttatag gggatacacg gagaaaaggt 22681 cacatgattc ctatcggctt caatgtaatg cagacgtttt tacgggcagg ctttaagtta 22741 aaagaaattg taataaagga acagcataat tgcagttcaa ccggttactg gagaaatcag 22801 agtataaagt ataatttttt attaatagca catgagtatt tatttatatt caggaaatga 22861 gttttttttg ttttgctggt tgctttccgc tcatgccgaa ataattatct gaccttatgg 22921 attaaaagga ggatattatg aatagaggag ttattgttac cggaggagga cacggtatag 22981 gaaaacagat ttgtttagac ttccttgaag ccggtgataa ggtatgtttt attgatatag 23041 atgaaaaacg ctctgccgat tttgcaaaag aacatccgaa tttattttat tttcacggcg 23101 atgttgccga cccgttaacg ctcaaaaagt ttgtggaata tgcgatggaa aaattgcagc 23161 ggatagatgt attggtaaat aatgcttgcc ggggcagtaa aggaattcta tcttccttgc 23221 cttatgagga atttgattat atcttgtctg ttggattaaa ggcaccttat gaattaagcc 23281 gtttgtgcag ggatgagcta ataaaaaaca aaggcagaat tatcaatatt gcatccacac 23341 gggcatttca gtcagagcct gattcagagg catatgccag tgcaaaaggc ggaattgttg 23401 ccttgacaca tgctctggca atgtctttag ggccggacgt tcttgttaat tgcattgcgc 23461 ccggctggat caatgtaact gaacagcagg aatttactcg ggaagattgt gccgctattc 23521 ccgcaggaaa agtaggaacg ccaaaggata tatccaatat ggttctgttt ttgtgtcagc 23581 aggattttat aacgggtgag acaattattg tggatggcgg aatgagtaaa aggatgattt 23641 atcatgggga ttggaactgg ttttataaga ttgataagta atgctcggca gcccaaagat 23701 gtttggttga tgtagagatg ttatatttta tttatagata ttgtgtgtta aaaagattgt 23761 tgtttgaaat gacgggcacg atatggattg gcctcagtgc ctattatttt attgtcaaaa 23821 attggaccaa aataaaaggg attgaaaatt atataaaata tttctgttga ttcttacaaa 23881 tcgcggcgta aaagacgaaa aactgggtac tattatatta agatgaacat tatgagaata 23941 aggagagggc attatgagcg aaataattaa taaccgcgaa tacaggcaga aagtcttgaa 24001 agagttgatt agggagctgc atgacggaaa gagtgtcgaa gaaataaaac caaggtttga 24061 agaattaata aaagggattt ctcctgctga aatttctgaa atggaacagg ctttgattat 24121 ggaaggcatg cccgttgaag aaatacaaag actttgcgat gtacatgccg ctgttttcaa 24181 aggctccatt gaagaaatac acagaccgca gaaacctgaa gaagtgccgg ggcatcctat 24241 ccatacattt aaactcgaaa atgccgaaat aaggaaactt gtcgataatg aaatcagacc 24301 gcagttggaa ttgtataaaa atggagacac agctgagagt ttaaagaaat taagagaagc 24361 gtttcaaaag ctttgggaga tagacaagca ttattcaaga aaagaaaatc tattattccc 24421 gtacctggag aaatacggca taactgcacc tcccaaggta atgtggggtg tggatgatga 24481 aatcagggca gatataaaag agataaacaa caagctttca gcgaatgctc aaaatcaaaa 24541 tatacctttg gagaaagcgg aagaagcggt aaacagggtt attgaaatga tttttaaaga 24601 agaaaatatt cttttcccaa tggctttgga gactttaacc gaggatgaat gggctgagat 24661 tgccaggacg agcgatgaaa tagggtattg catgattatg cctgaagcgg aatggaaacc 24721 tgcccgggtg gatgttgtgg aaaaatcaca aaaagaggga gttaagtctc aagaaaaccg 24781 gggctgtgtt gaatttgacg cgggatgtct tacaacggaa gaaataaatg caatgctcaa 24841 tactttaccc attgatatta cttttgtgga taaaaacgat actgtaaaat actttaccca 24901 gggaaaggaa aggatttttg cccgtcctaa aacaattatc ggaagaaagg tgcaaaactg 24961 ccatcctccg gccagtgtac acattgtgga aaagattata gaggatttga aaacaggacg 25021 aaaagaccat gaggatttct ggattaaaat gggtgaaaag tatgcttata tcagatattt 25081 tgctataaga aacgaaaaag gcgaatacct gggaacaata gaagtgacac aggatattgc 25141 tcctatacaa aaaattacag gtgagaaacg attgctttct gatgcttaga aaaaagggaa 25201 gtaagtgctt acgaaaactc ggggattcaa taacctcggg tttttattat ttattttgca 25261 aaagactgaa acaattcttg tcataagtct tttaaagccg ataataacaa aaaaagtata 25321 aaaatatata cagtcgcttg ataatgattt ccatcaatta tataatatta ttagtactat 25381 ccaattttat tattactggt tgtattaaat agtattttaa attttgggca agagtacaaa 25441 aactttattt ctcacaaaaa aataaatatt taatttcttt tataaatgaa aacaaagaac 25501 agaagagaag gatggttata aaatggtaaa caaatgtata tgagctatat gatggttgag 25561 taaccgctat aaatcttaca ggtccatatg agcaagtttc aaccggaagg ggcgattctt 25621 tttccacgag acataatttt aaaaaacaag gtttttacat atattggata ggtgcttttt 25681 aaatcatcct gtgacaactt tctgatgttg tttattgtca agctgttaat tgcataaaag 25741 gcaatgattt ttatggtgtt tctcatttct tcatcgaaaa cactctcttt aaacggagaa 25801 agatcaaaga acgcttgttc tgaaaaacag aattcggtat aatatgggta aattcaaggt 25861 gtaaattctt tctgaatgag tggtatgcaa atggtaaagt ttgctactgc aaagcctgcg 25921 aggttgcaag taaatgcgtt gctgatattg aacaaacaga gaaaatgacg gggaaataat 25981 agatttactt ggctgacgaa aatattggaa gaaccaaaag aaataagaaa gaatggaggc 26041 acattatgat atttgtatgt tatccgaaat gcactacctg ccagaaagca aagaagtggc 26101 tggaggcaaa cggcatagtt tttgaggaaa gaaatataaa agaaaacaat cctacaatgg 26161 aagaattaaa ggactggcat aaaaagagcg ggctgccgct gaataaattt ttcaatacca 26221 gcggactttt gtataaggaa cttaagctaa aagacaagct tccctccatg agtgaggaag 26281 agaagtacaa tctgctggcc tcagacggta tgcttgtgaa gcgtcctata cttatcggtg 26341 acgattttgt tttggtgggc tttaaagaga ctgactggaa agcctcgtgc ggtatcgaat 26401 agccggccca tgcgatgaca gcatgtatgg cagcataata gccggcaaag gcggttttcg 26461 gaaaaccaaa atgccaaact caaataaatg aagcctggct ttcaagctct tttcttactt 26521 tggcgaaggt gcctttaagt gaattcaaag gtgaattcag ccaaaagaaa agagcttttt 26581 taatagtgaa atttaataat taaatctgtt atatggggaa gggtgatata aatgacgaca 26641 tgtaataatg aattaataaa ttgtaaaatt tatacaaata aagtatttgt atatggaaca 26701 ctaatgaaag atttttgcaa ttacaaaaga tatcttgaag gccggataag tcgtataaca 26761 ccgggcaaaa cttatggatt gctttatcat ctgcctgaag gatatccggg tttgcttccg 26821 ggaagcggaa taattgaagg agaaattgtg gaacctgttg ataaaaaact tctgaagtct 26881 ctggacagac tggagggtta taataaaggg agcagcaata atctatacgt tagggagcta 26941 aggaacatat tgacagagga cggggaagag gtgccctgct ggatatatat ttacgccgat 27001 gaaaaatatg caaaagaaaa tgggatttta gtgccggatg gaaactggag gaactttatg 27061 aagaggaaaa ttgatatgag tggtttatga aattctcgaa gataatgccg ataaaattat 27121 gagagaattt gttagaaatg ttaaacttgc agaaaaaaac cgattttaga atgtttggat 27181 ttaacaatct tcggtggttt gtatgctgga cattgcatca aaatgggtga ttttcataaa 27241 tggcagcttc ttgaaaaatg ggtctgaaac agtacagagt atgaatatga ccctggtgag 27301 ccctttagaa tgggcggatg gctggagaaa catcttaatg catatttata ttatagggaa 27361 gaggaaaagg cttcaaagct tattccgctt gatttactaa tgccgataaa ggaaaaatag 27421 ttcatcaatt gaaaatttgc tttttcatcc cataagatat gatcctcttt acagtaaaca 27481 gttttttata ttttcactgt ctactgtaag gggagcatat taaagtttac tttatgagtt 27541 tttttcgata taatgttcga ggagataatt gtacgttatc aacctgtatt ttcataatat 27601 tgtaaagggt ggaaagaagg gattctcctg aacagataca ttattgcttt ttttcttttt 27661 agttttattg gttggattgg agaaagcata tattgcacta tatgtgaaca taaacgggca 27721 agccgcaaat ctatttttgc tttgatttgt atgatatatg gatgcggagc gttattggct 27781 ttttttacct atgatttgat ggaatccggt cgtctgccga atattaaatg gtggatgata 27841 tttatatttg cttttgttac aagcatggtt ttaggatacc ctgcttcgtg ggcttttgaa 27901 aaactgttca aggaacggtt gtgtgattgc actaatgttc cactgaacat taacggaaga 27961 ataagtgtgc ctacgtctgt tgtatttggt gctgtatcaa tacttatggt taaagctttg 28021 gtaccgttgg tgaacaaagg acttaacacg ttatctgaag ctttgctgga tattcttgct 28081 tatgttcttg tttcaattgt gttaatagat accacattga taatatcatt aatgacggat 28141 tttcgaagat atgttgtttt ggtagacggg ggatttcaaa atcatatagc agtttttgca 28201 gaacactttt atgccaatcc ggattcttat tacaatagag taatgcaacg tgttggagat 28261 tttaaacttt cagtaagcaa aaatcttatt gaaaagcagc tttgtgagga ggagtttgct 28321 gaattaatta aagattacct ggaatatgat gtgataaagc agatggatga gcatattcat 28381 catggtacaa ctacaacatt gcagcactgc gaaaatgtag catggatttg ttacctgctt 28441 aataaaaaac tgaatttgaa tgcgaacgaa aaggaactgg tggaagtggc aatgcttcat 28501 gatttgtttc tctacgactg gcacgacggt gatccagcga gaaggataca tggctttgtt 28561 cacgctgaca ttgcatgcaa taacgcaata aaacattttg gcataccgga aaaacagcag 28621 gaggctatac gcagtcatat gtggccgcta aatattacga aaattccgaa aagcagggaa 28681 gctgtaattt tatgcattgt agacaaatat tgcgctctta ttgagacagt gcgcttaaac 28741 aagcattttg gattaagaca ttgatgaaag atgggacagt attatttatt gtgtccaatt 28801 atttctatat tttgtttttg tattccgctt catgaaatta tattgtttga atttttcttt 28861 tcaatcattt ctattattat tttacggctt attatgatga ttacaaggta ttaagtttgt 28921 taagcgatca tgagcttcgc aattcttttt tgcgtgtttt tcagataatt agcaattcat 28981 tgatttcagg aactgatatt ttgctgcgaa atactgagac cgcttttttt aagctctctg 29041 gcgagagtat tggaaggaga ttggctcatc cttttatcgt ggtattttcc aaatatactc 29101 ttgcaaggaa acaaatgttt aagtataatg tacacagcaa aaactacaga tatttatatc 29161 gagttcgaca taatacagaa gtgttgagtt gcttattgaa agccggtttt ataaggttaa 29221 actgactatg taacttaaat gatataaatt agggggaaga aaacgataat gaatgtaaaa 29281 aagagactgc tatcgtatgc cactgtactt tttttcctat gtattcagct tttgactgtg 29341 agagcggaac cgccggttga ttttaagggc tttaatgaca ttgaaggtca ttgggcacag 29401 ttttggatcg agttaaatgc taaactggga aatattgcag gttatgagga cagtagcttt 29461 agaccgtctc aaagtgttac cagggcggaa tttgtaacga tggcaaacag attttttaac 29521 agaggaggcg gtgaaggact tgaatgtacc ttcaccgatg taaatgaaaa cgattggttt 29581 tttatggatg tggctgttgc cgagaaagct gtatacatca gcggttatcc tgacggtact 29641 tttcgtccga atgagttgat cacaagggaa gaagcatctg taattttgtg caagttaata 29701 aacagtgatc ccagaacaca tgccgataat attgaattta ccgattcaga cagcatttca 29761 ccgtgggctt acggttatgt aaacagcttg gtttataatc acataattaa aggatatcct 29821 gataatacgt tcagaccgaa aaatcctgta accagagccg aggctgttgt tcttctggat 29881 aatgcactta tgagattaat ggaaccgcct atataccctc tacatattcc cggctcatac 29941 ggtgagagcc cgtcaccgtc ggaaacggct acaccttcac cgacacagaa aaatgcggat 30001 gataaataaa cgggtaagga actgtcaaaa tcaagaatat ttctgctttc ttcagaatat 30061 gtttgacttt agtcgtatgt cgccaagaat taaaagtttt aacaagcatt aaaaatcctc 30121 cggcgcttaa tgccaccgga ggatgagctt ttttgcgtat taatcaaaaa caataacagc 30181 ttttttattc ttaatcctca gaagaattgt ttccatgatg cggaaataat gattcaggtt 30241 tttggtttca agataagacg taatcatatc ctgtccaatt accaaatcta tattttgagg 30301 ttcggaacag acaagaacag ctttgtcatc ctttaatacc ggcgtgctga aaatattgcc 30361 gtccagaagc ttatttattc tgtcatattc agttgttccc gtgcccggct gtattctttg 30421 cagttgaaca aaaagatttg ggcttacaac aagagccttt cttcctacga ttccattctc 30481 tatgaatttg gccaatccta ttgatatgtc tttgaaagga ttttcgcctt cgctccagtt 30541 cgatatgggg aatttaacaa ttccgtcttc tgtcagcaag cctttgtatc ccaattcatc 30601 attgccgtaa aagatcaatt tatcctccct taaagcgcat tgggtggcag ctctggaagc 30661 tgaggacaaa tcaacaggca accccatttg ctcgctgaat tccaagtccc tccacagaag 30721 tgaaaagtct tcattaatca aaggaatatg ctggtatgtt cttcccctga taaccgaaat 30781 gtttccttcg gtttcgtcca attctgatat attgtcaaca ttaatggctt gaatacctgc 30841 gcccaagggt ccgtaaatgc ttataaatct tcttcctgtc aggattttct ttgctgccga 30901 tacaacggcc tcgtcaattt tttcccaaag gtcggcagat attggagaac cttctcttga 30961 taagaaatcc atattctccc tccttatttg tctattaagc ttcctatagt gctttcagtt 31021 ttgccggaaa gtggttttgg agtaatattc aattgctcaa gcatttcttt aacctcttgt 31081 tctccttcgg cgaagtgctc tgcttcttca ggatcaaggt agcgaagcaa tgtcattaat 31141 tctcccacat gagctttttc ctcatccctt atgtctgcaa tcactttttt tgcaacaggg 31201 tcatcggtag cttgtacatg agcatcgtaa acaaaaatgg cttcaagctc tcccgcaata 31261 ttaagcctta ttgcctgaat caattcttct tttgtcaatt tccttgggac attgcctgcg 31321 aaaggatttg caaaacttgc cataatctat cctcctcttt tgatttgatg tgaaacttct 31381 gttcattctt ttattcatac ccatattata ctacttttaa accataaata tagtaaagtc 31441 gcatcaaatt aaaatataat aaaccggaat gctttttata aaagagtaaa tccataattg 31501 acattgatca gaacgggtgc tataatagat aaacgttaac tagttaataa ttaacatcat 31561 aatggttaac aagctaataa tggctttatt ggaaggagat gtgggaagta ggaaatatgg 31621 ataaaaatat ggataataat tatattgata aaatcagcaa caaggaagtc attcgtcaat 31681 taattatttt tgccatgaag catagaagaa tcatgcaaaa atttttggat gaaaccggtg 31741 tctatcaggc ccagcatcgt ttgcttatgg aaattttccg taatccggat gcctcgcaaa 31801 acgatattgc caggtcgatg gatgtgtctg cggcaacaat agcggtatcc ctgaaaaagt 31861 tggagaaagg gggatatatc aaaagagaga cggttgaaga ggataaccgg ttcaataaaa 31921 ttaccattac ggagaaagga aacaaagttg tggagcaaag caagcaaatt tttgatctgg 31981 tacatcaaaa ggtctttgag ggttttagtg aagaagaaaa acgtactttg tttactttgc 32041 tgcaaaagtt gaattccaat ttggacagaa tggaagcgga aacaaaatag aaaggggaag 32101 gatataaagg atgaggcggt attggaagta tgtaaaaccg tatttatctg catttatcat 32161 agggccgatt tttatgattg tggaagttat cggtgaagtg attatgcctc tgctactgag 32221 caatatcatt gataagggag ttattggcgg cagaggtatt tcatatatag taacaatggg 32281 tataataatg atagtcacag cgctgttcat gatgacaggc ggtgtgggag gagcctattt 32341 tgcaattaaa gcatccacgg gatttgccaa cgatttgaga aaagatttgt tcaggcaaat 32401 tcagaaattt tcctttaaca atatcgatca atataatacc ggttctttga ttacacggtt 32461 aaccaatgat ataactcaga tacaaaatat gattcaaatg atgctgagat tggccctgag 32521 ggctcccggt atgctcattg gtgctcttat aatggctttt gccatgaatg ccagactggc 32581 attggtaatc ctgtgcataa tacctttgct gtccctggca gtctacttca taattaaagt 32641 tgcatttcct ctgtttataa ccatgcagaa aaagctggac gcgcttaact ccaccactca 32701 ggaaaattta accaatatca gggtggtaaa gtcgtttgtc agagaacgtt atgaagagga 32761 aaaattcaaa aaagccaaca tagacttgaa agaaagcaca atgaaggcaa tgaagattgt 32821 tatctttacc ataccggcca tgagccttgc aatgaacatc acaattttgg cagtggtttg 32881 gtttggcgga aaacagatta ttgcgggcag tatgacctcc ggtgtcctta ccgcatttgt 32941 aaattatgtt atccagatac tcatatcact tgtaatggtt tcatttatta ttctaaacag 33001 ctccagaacc cttgcatccg taaggcgtat caatgaggtg cttgatacag atatcgacct 33061 gactgacgag aatgccgtgt acaaggataa aactgttgaa tacggcaaaa tcgaatttag 33121 agaagtttac tttaaatact ataaaaacaa tgaaaaatgg gttttggaaa atatcaacct 33181 cgtgataaat ccgggtgaga cggtcggtat tatcggctca accggcagcg gcaaatcaag 33241 ccttgtgcag ctgattccaa gactgtatga tgtggatttt ggcgaagtgc tggtggacga 33301 cgtcaatgtt aaagattatt cgcttaaaaa ccttagaaac ggcgttggta ttgtactgca 33361 aaagaatgtc ctgttttccg gtactataat ggaaaacctc aaatggggag acgaaaatgc 33421 cggtgacgat gaggtgtaca agtttgcaga aagtgctcag gcacatggtt ttatcacttc 33481 ctttgaaaag ggatatgata ccgagcttgg acagggcggt gtcaatgtat ccggaggaca 33541 aaagcaaaga ttgtgcattg ccagggcatt gttgaaaaag cccaaaattt taatacttga 33601 tgacagtacc agcgcagttg atactgcgac tgaggcaaaa atcagagaaa gtttcagaaa 33661 tgagttgaaa ggtacaacga aaattatcat tgcgcaaaga atctcttcgg taattgacgc 33721 ggacaaaata attgtacttg atgacggaaa aattgtcggc ataggtaatc acgaagaatt 33781 aatgaagaat tgtgaaacat attcagagat ttattactca cagatggata agaaggtgac 33841 tgcataatga gccgtatcag tgaagaaaga aaagaaatat tgttacgcag atatggaaat 33901 ataaatacta ctgcaggtcc cggagcaatg aagccgggca gagggaaaat gtcaggaggc 33961 tttggcggac ccggcgggaa aagaccgctt ggatttggtg gtccaagagg tatgcgcggt 34021 gctgtgggcg gtgccaaacc gaaaaatgca tcggctacaa ttaacaggct gctggcttat 34081 atcggacggg acaagattaa aattctgttt gtttttgcgt gtgtactggg cagcagcctg 34141 gcaagccttg ccggaagcta tattttacgt cctgtcataa acaatctggt ttattccgac 34201 ggaactgcaa aagaaaaaat aaacaatctt gtaatcggta tacttaccat ggcatgcatt 34261 tatttggccg gagtggtatg ttcttacctg cagcagagaa tcatgatagg agtttcgcag 34321 aatgcgctga ttagaatcag ggaagagttg tttcgcaaga ttcaaaagct gcctttaaaa 34381 tatcatgaca ctcacactca cggtgatata atgagccgtt ttaccaatga ccttgatgcg 34441 gttggagaaa tgctcaataa caccatgtcc cagatttttt caggtattat taccctggtt 34501 ggcactgttg ctcttatgtt ttttacaaac tggatacttg caatcattat catcgtgacg 34561 gtgcctttga tggtctacgt gggaggcatg atcggaaagc agagcagaaa atatttcata 34621 ggtcagcagc aggccctcgg tgcggttaac ggatatattg aggaaactgt tacgggtcaa 34681 aaggtgataa aagtgttttg ccatgaagaa acagtagtgg aagaattcga gtttttaagt 34741 gacaatttgc gtgaaaaaca gagaaaggca cagttctttg gaagtattat ggcacctgtt 34801 atgggtaatt taagccaaat aagctatgcg ttgtctgcca caatcggagg tgttctctgc 34861 ctgacgctga attttgatat tggcggcctt gccatattta ctaactattc aagacatttt 34921 gcaaggccga ttagtgaatt gtccatgcag atgaatacga tttacgcggc attggccgga 34981 gcggagagag tgtttgaagt gatggatgaa acacctgaga agggtgattc cccggacgct 35041 atagaaatct gttccgaagc aaaccgggtg gaaggagcac agccaattaa aggagaagtg 35101 gtgttgaaaa acgtaacctt tggttatgta ccgggaaaaa ccgtgctgaa aaatattaat 35161 gtaacagcca aacccggcca gaaaatcgct tttgtgggtt ccacgggtgc cgggaaaacg 35221 accgttacga accttataaa caggttttat gagattgaag aaggagaaat actgattgac 35281 ggtatcaata tcaagaatat taaaaaggac tcattaagaa gcaatatagc aatggtgctt 35341 caggataccc atttgttttc cggaacggtc agagagaata ttcggtatgg ccgtcttgac 35401 gcaaccgatg aagaagtcgt tgcagcggcc aaggtggcct gcgcccattc ctttatcgaa 35461 aggctgcccc agggatatga tacggtattg gatggggacg gagcgaattt gagccagggt 35521 gaacggcaac ttctcaatat tgcgcgggct gccatatcaa aagctcccat tctgatactg 35581 gacgaagcca ccagttcggt tgacacgagg accgaaaaat acattgagcg tggtatggac 35641 aggttgatga aaaaccggac tacttttgta atcgcgcaca gactgtccac cgtgcgaaac 35701 gcagatctga ttatagtgct ggaacacggt gaaattatag aacagggaac ccatgaagaa 35761 ctccttggga tgggcggaag atattatcag ctttatacag gagcggttga actggactag 35821 gagtgattaa agacggaata ataacacagc aaaaaagcag ggaacatatt agggttggcc 35881 tgttatgttc cctgcttaaa tgttttttgc tttcattcca ttttaattca ttattcattt 35941 cattactctt catcctgcag tgcatcgtat ccttcttcgc cggttctgat ttttataacg 36001 ttttcaacat catagatgaa gatctttccg tcacccatat tgcctgtata cagtgccttt 36061 tttactgtgt cgaccacggt ttcgacaggt atcttgcaca ctacaatatc cacctgaact 36121 ttggggagaa gtctggtttt taccggcaaa ccgcggaaat actcggtatg tcctttctgc 36181 ataccgtaac caagaacatt tgttactgta aggcctgtaa taccaatttt gtcgagagcg 36241 ttctgaagct gtgtatattt gtcctggttc gtgataacgg tgacttttgt catctttgct 36301 ccgggatggg aacgattgac cactgggatt gcagcttccg gagttacttt gacggaagaa 36361 ggctttattg tttcaacctg gctcattgcc actatgctgt ctccgttacc gttgcctgaa 36421 gccgtaatag gagctacgat ggcaaagtca ggataagcgg agtttccgtg ttcaccgatg 36481 tccagaccct ggatttcttc ttcaaggctg acgcggatac caattgtttt cttaagaatg 36541 aaccatacaa gagctgatga tgcggctaca aatgctccaa cggcgataat accgataatt 36601 tctgctccga gcagtgagaa accgccgccg aagaacaaac cgttgactgt ggaaaggctg 36661 gttacacctt cctgtgcaaa gagtcctaca cagagcgtac cgaaaacacc gcacaccagg 36721 tgtacggaag ttgcgccgac tgggtcgtca acctttatcc ggtcaaagaa tattactgag 36781 aatacaacga taatacctgc tattgcaccg atgatcagcg aacttccaac acttacataa 36841 gcacagctgc cggtgatacc tacaagtcct gccagacaac cgttaatggt catgccgaga 36901 tccggtttgc caataaagct ccatgatgtg gcggtggcgg taagtatagc tgcaatggcg 36961 gctgtattag tggttactat gatatgcaca acgtcctccg gattttggaa actcatggtg 37021 gagccggggt tgaagccgaa ccatccaagc cacaggatga aaagaccgat aactgcgagt 37081 gccaggctat ggccgggaat tgcttttggc tttccgtcct tgtcatattt tccgtgacgg 37141 ggtccaagta taatagctcc ggtcagagcc gcccagccgc cgacagagtg aacaacggta 37201 tcgccggcaa agtccataaa accaaggttg gcaagccagc cgccgcccca tatccagtga 37261 cctacgacgg ggtaaataaa gagggtcagt atgaaagaaa atactataaa ggatatatat 37321 tttatacgtt ctgccactgc accggataca atggttgctg cagtaccaca gaaaacaagc 37381 tggaagaaga attttcccca gaagggtacg gtcgacgtca aagtgtcttt gtagaagccg 37441 agatcggaac cacccaggat aaacagttcc tttgtgccga taatcggatt gtctccgccg 37501 aacatcagtc cccagccaag cagcatgaag cccagcgagg aaactgcaaa aacaataaag 37561 ttctttgaca ggatgtttac cgtatttttt gatcttgcaa aacctgattc gaccgctgcg 37621 aaaccaagat tcataaagaa tacaagtagg gctgcaaata ctacccaaag ggtgtcaact 37681 atcattgtag tattcataaa gcattcctcc ttaaaaaaat tgaaggcgtg tattttattg 37741 aggcatcaat aaaacacacg cctttgtgcg caattaagtt ttaactatga atttgtttct 37801 cctgtaattt tggatgagtt aatgggttac atgaagaagt ttggtgtaaa tgactttact 37861 tctgaaaagc tcctgcatgt ttttgaaatt tgtcctcacc ctttccccct aaaataactg 37921 aaggcgttgc tggcctttgc caacagcgcc ttcgctatta cttattataa taataactca 37981 aactgattta tttgtcaata gaaaaatatg ataaaatagt agtctgcaat aggactctat 38041 tttttagttg ttttttatct tttaaataaa aatgataaat ttgaaaaagc gttttaccga 38101 taatgtaatt agcaattaaa gagcaaatgc atttgccaac cttcgagggt taattctatt 38161 gtcaatagac ctgttgctca ttgcaaacct gtcaaacttt ataaaaacct ttatctatga 38221 gatatagcat cgatgcgctt cagaacgtag ggagggataa agtataatga gaagaattgt 38281 atgctgtggt ggttaaagaa gatgattata tacgtttgtg gtgattttcg aagtaattga 38341 taacgcaact ggattaaaaa gatatgttaa agggcacaat attttacatt tttcaaggga 38401 cataaaatag aaaaattatt cccaagatta tgacaaaacc tatattgtag taatttgcgt 38461 aaaaggcata tcctcttgaa ttgatcgtta gcgccttttc aaagttcatt gtcatttctg 38521 aagaaagtct tgtcgaataa ttccaaaata ataagaatgt taataacaaa tgcataaaaa 38581 aattgggaaa gtaagcaact atactaagat attacatagt tgcaaaaagt tactggatga 38641 aaatgaactt gtaacggtaa atgagacaat tcagcctgaa aaaaaggagg atttcttatg 38701 tttaagtcat ttaataattt aagaattgga gtcaggataa ttataggttt tttcattatt 38761 gtggcgatag cgtgtattat aggagttgtt ggaattcaaa atcttaagaa cgttcaggat 38821 tcatatgcac ttgattatga aagtactgtc gatgcattgg agtatgttga aagaatcagt 38881 tctcattttc agcaaataag ggtaaatgtc tttggttttg cattgtctta cgactcagat 38941 gaaaaaaggg agtattatac tgaaaggatt gcagaacata taaatacagt cgatgagagt 39001 atcaatggct atcgtgagat attgagtaag tatgatgcat ctgaagttga aacggagatg 39061 aagctgcttg ataatattca agcggcatta aatgaatttg gagtcctaag gaacaagatg 39121 atgaacgacc ttcagaccgg tttgataagc agggaggaat ttgtctcttc attttcaaaa 39181 ggcggagaag ctcacaattt ggcaagtaat gtggacaatg ccatccagga actgattgac 39241 tataatattg attatgcggc aaatcagatt tcaaaaaaca aaaaacaggc ggacaactca 39301 attggattaa tggttatggt aatagctgtc ggcgcggtat ttgcgcttgt attaggtctt 39361 attatctcca atggtatatc caagcctatt accaaagtgg ttgctgctgc cggcaagctt 39421 gccgaaggag atatggatat aacttttgat attaattcca aagatgaaac aggaaaactt 39481 gtggatgctt tcagaaatct ggtcgaaagt acgaaaaagc aggcatttat agttgaaaaa 39541 atcgctgacg gggatcttac ggttgatgta cccattcgtt cccaaaagga cttgctggga 39601 cagaagctgt ctgaaatggt gcacaatatt aacaatttga taatgaatat tgcttccgcg 39661 gccgaacagg tttcagcagg agccagacaa atatctgatt ccagcatggc actttcgcag 39721 ggtgccacgg agcaggcaag ctcgatcgaa gagctgtccg cttccataga agaagtagca 39781 tcaaaaacaa agataaatgc cgataatgca aatcaggcca atgacttggc tgagaaagca 39841 aagacttttg cacttaccgg aaatgatcat atgcaggaaa tgttgaaagc aatggatgag 39901 attaatgaat catccaataa tataaataaa attatcaaag taatagatga tattgctttc 39961 cagaccaaca tactggcact aaatgccgca gttgaggcag ccagggcggg acagcacggc 40021 aaaggttttg ctgttgttgc cgaagaggtc agaactcttg caggacgttc cgccaacgcg 40081 gcaaaagaaa cgacggcttt gattgaggat tcaataaaga aagtggaagt cggagctaaa 40141 attgcgaaag aaactgctga agcgttggag aagattgtca gtggcgtaga atctgtgtca 40201 aatctggtaa gtgatataaa tgaagcttca aatgagcaag ccactgcgat tgctcatatt 40261 aatcagggta ttacgcaggt atcacaggta gttcagaaaa attcagccac atcagaggaa 40321 agcgcagccg caagcgagga actttcaagc caggctgaaa ggctcaaaca gttggtggaa 40381 aaattcaggc tgaagaaaac ttctgtcacc atggattctt atggagagct taatccggaa 40441 attatagata ttcttggaca aatgagcaaa aataaaaata aggaaaaaga agcggaaata 40501 gttttgaatt gacagccggg ctgtaaaatg ccaatttgat tccgttaaaa tttattacgt 40561 ttgagggatg gaattctcca tcccttaatt gcatattctg atttgaatga gcagacagtt 40621 attttgttgc caaaggtggt tgtattcatt gttattgtaa aaaatcaaat gttattacgg 40681 attttataaa cagcaaagct tttgaaaatg aatttaataa cttgtataat aaataatgta 40741 agttaatatt gcaatttatc gctttctttt gtttacatgg gggtgatatt gtgataggta 40801 tattaagcat tgattttgat tattttatta atgcttcatc acaggcccgg gacatgtatt 40861 ttccaaaagg aagtgatgag atacccgaaa ataaacttaa gtctgtgtgg aaagaaagat 40921 atttaaaata tccggagctt aagaaaatag gggtaattga cgattttcat ttcttaaaaa 40981 aatttctgaa ggaattgaag atacccaaag aaaatttcat gaaagcagac agtcataaat 41041 atataaaaag tattattgaa aaattgccgg aaaaatcaca atttaagata gtaaatattg 41101 attttcacca tgactactat cactattata gaggtaatga ctattacaat tgcggcaact 41161 ggttaagaag agttcttgaa gagcggcctg atgcgaaggt aaaatggatc agaagagagg 41221 actcgcaaat ctactgtctg gacggaatat tcccatttga acatactgat gatataaaat 41281 ctgtttataa tgaaaagttt gattatatct ttctctgcaa aagccctgaa tggaccccgc 41341 ctcatttaaa tagtaaattt gaggaattat gcagaacaat agaacaggat acaattcttt 41401 attccaacat gttttcaagt gtgtcttaat tttatttttt tatttttatt gtgagaaaaa 41461 ttaattaaaa gtgatataat atagcttgtg caagaattaa caaactaata gttttccaga 41521 tttgttggat aaatagattt gctgataaaa aataaagtat ttgtgtctga aaggaataaa 41581 atacattcag acaagtttag atagacagga ggaaaaagaa atgcaggaag tttatgaatt 41641 tttaaagaag tgcggaacat attatttggc tacggtagaa ggagatcagc ccagggttag 41701 accgtttggc acggtggata tttttgaagg caaactttat atccaaacag gcaaagtaaa 41761 agatgtgtca aaacagattc aggcaaatcc aaaagtggag ctctgtgcct ttgccgacgg 41821 caagtggctg agagtgtcag gcaagcttgt ccgagatgac agagtagagg ccaaaaagca 41881 tatgcttgat aattatccgg agcttaaagg tatgtattct gcggaggacg acaatacgga 41941 agttctttac tttgaagatg cgacagctac tttttactca tttaccgagg cgccaaaggt 42001 aattaaattt tagtaatact gccaagattg atgaaaatgg tagaatgtgg cgtatttttg 42061 ggctttttcg agaatgagtt ctttctcgat aaagctcaat tgttttttgg taatcatagt 42121 gacggaaaat aagaaagata aataaaaaat ggggggtcaa ttgtatgtgg atgatatttg 42181 caatactgtc tgcagtattt gcagcactta cttccatact cgcaaaagtc ggtatagaaa 42241 atgtaaattc tcaccttgca acggcgataa ggacggttgt ggttgtgatt atggcgtggg 42301 caatggtctt ttttacccat gcacagggtg gtttgtccca aattagcaga aagagttgga 42361 tatttttaat tctgtcagga attgcaaccg gtgcttcatg gctgtgctat tacaaggcat 42421 tgcaaacggg agatgtatcg aaagttgtgc cgattgataa aatgagtgtt gtaattacaa 42481 tagtccttgc gtttgttttt ttgcgcgaaa aatttactgc aaaatcactg attggctgta 42541 tattgcttac agcaggaact ttggtaatgg ttctgtagaa caggggacgg atagggcaaa 42601 gccttgttat atattgacaa tattccactt gtggaatata ataatattat acaagtggaa 42661 tatgtggtga taaatatgct aaaacacgga atattgggtt tgttaaatta cggtgatatg 42721 acaggatacg aaatcatgaa agtattcaga gactccttaa gcttcttctg gactgcaaat 42781 accagtcaaa tctaccggga gcttaatacc ctgaaaaaag acggatttgt gacagacatt 42841 gttgtgaaac aaaccggaaa gcccgacaaa aaagtgtttt ccataaccga aagcggacgg 42901 gaagagctga aacgctggct gagagagtac gactacggaa acaggaatag tcctctgtgc 42961 atgaaagtgt ttttctccgg agagttaccg aaagaagaaa atatagaacg cctccgggaa 43021 ataaaaaatg aggcgcagca ggccatagag aggtactctt ccgtatttga aaccatgaaa 43081 atttataagg ggatggtagc acgtcctgag gattctgttt attggaatat gaccgtagag 43141 tacggaatac gttatatgaa gatgttgtca gaatggtgcg actgctgcat taaaattctg 43201 gaggatgttg aaaaatgaaa atacttgtta taaacggaag tccgaaaggt gatgccagca 43261 actctttgaa acttaccaaa gcctttctcg aaggtatggg agacaatgat gtaagggaag 43321 ttacggtgtc caggctgaat ttatcgccct gcaagggctg tttttgctgc tggagcaaaa 43381 cgcccggaaa atgcgtgata aatgatgata tgagccgggt tatagaggat gaattgtggg 43441 ctgacattat catttggagt tttcctttgt actattttaa tgttccgggc ccgcttaaaa 43501 acttgattga cagacagctt ccaatgaacc ttccctttat gacggagcga gaagacggta 43561 tgggaagcgg aagtcaccct tcaagatatg atatgagcgg caaaagatac attttaattt 43621 ccacctgtgg gttttattcc gccgaaaaaa attatgaaag tgtaaaaagt atgtttgact 43681 atatttgtgg caaaggcaat tatgagacaa ttttctgcgg tcagggagaa ctgtttcgtg 43741 ctccggaatt gaaaaaaaga acggacgaat acctcgatat agtaagaaaa gccggcagag 43801 aatatatatc aacaggtatt tcaaatgaga caagaagcaa gctgaatgaa cttttgtatc 43861 ctaaggaagt atttgaacaa atggctgatg ccagttgggg aattgacaaa gaaaccggca 43921 atgaagttga caagagtctt tctttcacca ggcaaatggc ggctttgtac aataagggaa 43981 gttatgacgg aaaagaccgt gtgctggaga tatgttacac ggatttgggc aaaacctatc 44041 aaattttatt ggggaaagac ggcagcaaag tttttaccgc cggcagtttg ccggcaacaa 44101 caagaattga gacaccgtgg gaagtatgga catccattgc cagaggtgag ataagaggag 44161 atgtggcact ttttaaaggt atgtataagg ttaccggtga tttttctttg atgatgaatt 44221 gggataaata ttttagcaaa accaaagaac aacaggaaaa tgagattgac aaaagcctga 44281 catcaaagaa taaaaagccg tcaatgatga caatgctgat tccgtggatt acgttttgga 44341 ttgccgtatc cattaacgcc aatataggtg caattattac ccttgcagtt tgtgcatgca 44401 ctcccatggt tatggcacga aaagagctga ccgtttatga caaaatttca atggcggttg 44461 tatcactttt atcggttctg actttacaga atgacatgaa aataatatcc attgtggcag 44521 gataccatgc attcgggctt atgtggcttc tgtcctgctt tacacgagag cctctttgcg 44581 ccgcgtatgt caagtacgat tataacggtg aagatgcgtt aaacaaccct attttcatga 44641 aaacaaatta tgtattggcc gtaggctggg gaattttata tattttaaca gcgatttggt 44701 cgtggttttt gatgcgtttg aacatgatcg tgctgttgca aattctgaat aatgctgcga 44761 cctgggctat gggtattttt acgatatggt ttgtaagatg gtatccgcag catattgcat 44821 taaaaggcag gcgttaagag gtgtgtaacg gcagcaggcc tctttataaa acgcctgcct 44881 tttattatgc ctttctattg tactgtcatg ccaaaaaccg gcacacctct taactctgta 44941 ttttattctt gacaatatac agtttgacta tatataatat aactatatag ttcaactata 45001 cagttatact atatagttga actatatagc cacactatgg aaaggaagga aaaaatgaat 45061 ctggaaaaac atctgccatt gacagagaca acatattata ttctgctttc gttgcttgag 45121 ccgggacatg gatatgcggt gatgcagaag gcggaagaat taagcggagg acgtgtcaga 45181 atcgctgccg gtacaatgta tggggcgctt gagaatcttt taaaacagaa gttgattgca 45241 tccgtaccct cctcagaccc gcggcgcaaa atgtataaga ctacggaaga aggcgcccgg 45301 gtacttaagt tggaagtgca gaggctaaag catatggtcg atatttataa caggattcag 45361 ggagatgaat aatatgaaaa aattcaagat gttttggaat tttgatgagg aagaaaaata 45421 tttgaaagac atggcctggc agggatatat ttttaaaaag tactccatat ttggtttttg 45481 tcattttgaa tccggaaagc cgcaaaatct gaattacaaa attgattaca ggatatttaa 45541 agacaaaaag gaatttgata attatattgc attgtttgaa gatgcaggat ggaaacatgt 45601 ttatggcacc aaaaacagtg gaaaccaata ttttttgccg atgaatgaga aggccgggac 45661 agatattttt tcggacaggg tttcggctgc tgcacgatat aaaactttat accgaatttg 45721 tttggcgaat attgcatgtt ttatatttta cttatgcatt atattatttt ccgtcggcgg 45781 agatctttca aaactggcat ttttgactcc gggcttgtgg gaacgtacag gaagggcatt 45841 ctggtccgca ttcttttttg aactcccttt tgttttgctt cgcatgacac cgcttgtttt 45901 cttcatgaca gttattgttt tctatggtta ttggggctca aaggctaaaa agaattatga 45961 agctgttatg aatgaggata ccgacaagga atgatatgtt aaatgccaaa ggcttcaact 46021 tactgttctt attactgttc ttaattgatg ctgtagattg tttgaataaa cagccggttt 46081 tatacttact gaatatatgt caaataatag tcaggcatgc taatgttgtg tctgattatt 46141 attttttgtt aaattgtaag aggcattata ccgattataa tattaaaagt ttttttcatc 46201 ttatattttt tgtatattta tattttcttc ctgttgagtc tggattaaac gttccgtcaa 46261 agaattgtgc ggacttgcta tttgatatga aggtaaagcg taacgttaaa aatattactg 46321 caagggcgtt gataaagagt attggagagc aggcacagaa attgattcac aggaagtatt 46381 gattgaatga taaacagtac ttccagcttt agaaaagtag gaggaatatt atgaagcctt 46441 tcaaggattt ttcaaaccgg ctgaaaacaa gtataatacg ttttgctaaa gttataaagc 46501 gttttattac cggggtaata agcaatacga agaagttaag aataaaatta cgttcgaagt 46561 ttaatggttt gacggataat aagagggaca tggatggcag tgacaatgaa ggtatgtctg 46621 caagaattaa tttagaaaaa atccttgatt ttttaagcaa gccttttaga aatataaaga 46681 ttcgtacaag acttttcgtg tcttttacag cacttgtggc tcttatttta atttttaccg 46741 gtatgttgtg gtataaaaaa tccagtgaag caattaaaac gaaaataagt acttattcaa 46801 tacagattac aaatcagctg ggggactatt taaacaagga aatggacaga taccagaaat 46861 tcataaatga tttttcttcc gaaagaacat cttttcagga tgtactggtt caaatgaaaa 46921 atccggacat tgatgcgtat aaaagaagac agcttagcga aagtatagga gtatatatat 46981 ctcaaaaact tggtttgatg ggaaatgacg tggaattgtt gaaggtggtt ttgaatgatg 47041 aaatagaatg tcattatgga aataatagca taatgtcaaa ggaggcacaa aagaaaatta 47101 ttgaaaatat aaaatcatcg gacaagatca acaatattga attttacata aagcgggatg 47161 gaaaaggtat taagtgctat cccatgactt cgagaagaat tgtttctgta agtaatgcaa 47221 aaactatagg gtatataatt tgtgttatga aaagtgacta tattttaaag caatatgaag 47281 gaatagactt gggcgaagat acgaacatat tcattttgga cagtaacggg cttgttatat 47341 caagcaacag tgatgaattt gttgcgggct tggagtttcc cgacaaggat tttgttaaag 47401 aactgacttt aaaaaatgaa gagaaaataa atgcttttcc tgcgtatata aataacaaga 47461 gataccttat tacttatacg tatttggatg aatatggctg gtaccttgta agtaacatac 47521 cttactctta tttaaataaa gaaactaaca ggcttttagc aaccatggtc gttattttta 47581 taatatgttt ttttgctacg attttgcttt ccctggtgat aacccgcagt atttccgcgc 47641 cgctaagaaa acttgttgaa ttaatgaagc gcaacaggga cggaaatctt accattgccc 47701 aaaccgataa aaataaagat gagataagtg ttgttgtaaa taattttaat gatatgatag 47761 gaaacataat aaaaattgta tcaaaaggca atgaatctgc agtaaatgta ttatacagtt 47821 ctgaaaagat tgaggaatct gcaaataaat caaggattct tacatcgagt attgccgcta 47881 ccatggaaga aattgcgcaa ggtgcggcat cccaggcaat gaacattgcc aatgcttccg 47941 attatatgaa taaattatat gacggaataa aagaagttga agggaaaacg gcggttgttt 48001 caaatattgc aaaaaatact cgaatgctca gtgaaaaagc ccttggtact gttgagaatc 48061 tgaaggacaa gtctacagaa accggtgaag tatcaaagca aataattaat gacatcatag 48121 gacttaacaa tgacatgaaa gaaataaaaa agataataaa aatgatactg gatatttcag 48181 gtcaaaccaa gcttctggca ttaaatgcca ccattgaagc ggcgagggcc ggtgaagcag 48241 gaaaaggatt tgcagtggtt gcatccgaag taaaaaaact tgcaaaccgt acgaaagacg 48301 catccaatat tataaacgac atactgaaca acatacagaa gaaaacggaa ttgatagttg 48361 attatgcaaa caacaccagc tatattattg cccagcagtt ggatgcagtt aatgaaacgg 48421 ataatgcttt taaaactatt ctggaaggta tgttggatat ttctgaacag ataaatgaag 48481 tggatagttc tgttaaagag attgtatcac taaatgagat gaccaaaaat gtattaaata 48541 ccatatcggt ggtatcggag caggctgctt caacttccca ggaagtttcc gcaagtactc 48601 aggaacagct ggcaggagcg gaaaaactcc ttcagtatgc cggagaactt aacaaaatgg 48661 ctcaagagct taatgagacc atgtctattt ttaaaattaa tagttaataa atagtaatat 48721 gataatattt ttagattgac tttagaaatt ttgtattatt gtattattga agttagttga 48781 ggctaaaacg aaaaagatga gtattcatct tttttattta gccttgagtt agttgtgact 48841 aactttatac aggcgtttat attattcaga tatgaataaa ggttttctca tgttgagttt 48901 ttatgtaaat accgatcaga tacactcata tgaaagactc ttgtttattt tatgctgatt 48961 actctcaata tgagagagaa gagttgagag attaaatatg ataagatata ctaaatggtg 49021 taaaaagcta ttaagaatag tttatctttt aaacagacat aaagtatagc aagtaaaaac 49081 aataaagttg gggtgttttc aatgtggttt tggataataa tgtttttgtg caatctgatg 49141 ataccggtta ttatgattgg agtcggttat atgatgtata agcatccgcc aaagagcata 49201 aatgcaatat atgggtatcg aaccccaaga tcgatgaaaa atgatgagac ttggaaattt 49261 gcccatgatt gctgtggaag actctggttt aagctgggat tcattttgct tattcccacc 49321 ataattgcca tgcttccgtt tattaacggc gatgtaaaaa cagttggaac agtgacgatg 49381 ataattcagt gtgttcaagt cttagcgctg gtcgggtcta tatttccggt ggagtcctca 49441 ttgaagaaga actttgatga cgatggaaac agaaggcagg acaaaaacta ataaagaggt 49501 gtaaatttat ggaaagaatc agagttacgg cagggatcat tataaacaat gacaaagttt 49561 taattacccg gcgtgcgcca aacgaaaact ttgccggtgg atgggagttt cctggcggaa 49621 aaattgaggc tgatgaaacc cctgaggaat gtcttgcaag agagcttaaa gaggagctta 49681 atataactgt ttccgttgag ggattttgta cagaggttcc ttatgattac gatgacataa 49741 gcattgattt gattgcgtat tattgtacta tagttgacgg cgaaattcag atgtcggtgc 49801 atgacaaata caagtgggtg aaaatagaag atttattgaa ctatgacctc ttacctgcgg 49861 atgttccaat agcaaaaaga gttgtgaagg aaaaaggaag ctaaattcac aaaaaatact 49921 cggaaacgta aaaaacaatg gaattttatg atattattaa attgagtcat taatcatttt 49981 ttttgattta tcagactcag tttgggtata gaacttatgg actatgaaat acgaggagga 50041 tgcaatatga agaagctaaa gattgcagat ggaatacaca tgcttacaat gaatgttgaa 50101 gacatactgt ttgaaggaat atgggagctt gcaaacggag tcactcttaa ttcctatata 50161 gttcagggag aaaaaactgc aataattgac ggtgtgattg gatgggacgg aatacctgaa 50221 actctttata aaaatttgga agatataggc gttgatccaa agaatattga ttatttgatt 50281 gttaatcata tggaaccgga ccattcaggc tggatttcaa actttagaaa aattaaggat 50341 gattttacgg tgatatgtac cgacaaagct gcaaagatgg tagcatcctt ctatggtgag 50401 gacaagataa gggttgtcaa ggagggggat actctggacc ttggaaacgg aaaggtacta 50461 agtttccatc cggtaccgaa cgttcactgg ccggacacga tgtacaccta tgaaagagaa 50521 acaaaaaccc tcttctcatg tgacatgttt gggacatttg gcaggatggg agagcattgt 50581 tttgatgacg agctgacacc tgaagaagtg gatttctttg aactcgaagg aatgagatat 50641 tactccaatg taatggcaac tttcacaccc agtttgaaga aggccattga aaaagcgaag 50701 gagctggaaa taaatgttat agcacccggt cacggcccag tttatagaaa aaacccgcaa 50761 aaaattatag atgattattc caggtttgcc ctctatgcag aaggaacggg caaaaatgaa 50821 gttactatat tgtggggctc catgtatgga atgactgaaa aagtggttaa ttacgttgaa 50881 agcatacttc aaagggaagg aattaaatat aacaagctga aaatgcccct tgcaaccgaa 50941 agtgaaatgg ttgcaaccgt gtttaggtcc gcaggtgtga ttattggagc gcctacttat 51001 gagtacaagc ttttcccgcc ggttgcatcg gctttgaatg agcttggcag aaagaggatt 51061 acaggtaaga cggcattcag attcgggtca tacggatggt ccggcggagc agagaaagag 51121 cttgctgaaa taattgaaag aaacaacatg aaatggaatt ttatcgaatc cgtggagttt 51181 gaaggagcac caaaggatga agaccttgcc agagtggagg aaagagtgtt ggagtttata 51241 aagaagatga gggagaaggt tgtagaatag tttttcaatg acaaggagca ttggatgatg 51301 aaacagtggt acgaaaaatt aataatttga gcaaaaaaag tcgagatatc cttccaggca 51361 aaatgctacc atgtaatcgt tggaggtgag caaatgaggg aacagatact ggctgtgcag 51421 aggatgcagg attatattga agctcatatt catgaggaga ttacacttgc ggatttggca 51481 agagtatcgc atcaaagagc ttttgcccgc gaatttggct gcaatccgaa gcaatatgcc 51541 gaaaatccgg ttcccctctg tttgtttaag ccttacagcg ttaaatcccg gtaccttgga 51601 aggaggaatg gttcgatgga aaaggtaaaa actgtgtttg tccagttaac cgaaaggcct 51661 gcccgcaaag taattattaa acgcggaatc aaggcaactc attattttga gtattgtgaa 51721 gaagttggct gtgatgtgtg gagcttgctc accagtatta aatccatcag cggagagccg 51781 gtttgtatgt ggctgccgga gcgttaccgc aaacccggaa caagcgagta tgtgcaggga 51841 gtggaagtgc ctgtggatta tgacggtatt attcctgacg gttttgacgt tattgaactt 51901 cctgcagcaa agtatctgat gtttcaggga gagccttttg cggaagaaga ctatgagcag 51961 gctatcgaag aagtatggga agctgaaaag aaatataacc catcagttat tggatatgag 52021 tgggaccagg ataatcctcg aattcagctg gagcccattg gttcgcgagg gtacattgag 52081 tttgttccga tcaagcctgt gtaaatgaga ttgatattgg tgaaaattat gaagataaaa 52141 gtttggaggt aaaaaagtag tatcaatttc acatgaaatt cttgacaatt agtcagtacg 52201 ggttacaatt gtagtcagta ctgactaatt tgttatgaaa attgctatgg cataaaagcc 52261 ggatttaaaa tatgtcagag caaagtgtaa ggcgggcata aacaaggaaa gtgctaaagc 52321 gtttttaggg gtgtaatatg ctgttttgcg aaaagtacgg aaaagcgata gattttctct 52381 tggaaaaatc caacatagcg gtgaggtatc gcgtcacaag agaattgtgc gatggttcaa 52441 atcctaatga tttggaaaat cttcaggaag aattgattta ttctgaaaga gcggttagac 52501 tgattaactg tttgaaaaat cgaaaagagt accatggttc aactctttat gcagtggaga 52561 attccctcaa catgctggtt gatatgggat ttcaatatgg aaagggattt tcggagtttg 52621 atgaagttat aaatgagctg gctgatgagg caagggaatt gccggttgat aaaaatcatg 52681 tattacgcca tttgtcccat attgtagttg ttccttttct tttaagagcg ggatttcgtg 52741 atgaatgggt gaaggaattt accataaaga gaatctgttt aattcatgat tttgtaacat 52801 taaatcaata cgatatttat gatgacattt taaaatataa aagcataccc aaatgcttta 52861 gaaatcgtcc cattgttcgt ccggacttgt atgaaaacgg gtggtttaag attcctcttg 52921 agtatgacat ttatggattt gcatgtctga tgccagagtt aactgttgat ttgcaaagca 52981 aagtcaacga tattatttca tatattttag acagcagatt tcaagctata aaagacggat 53041 atggcatatt ggctgacaag aaaaggtatt gggctatggg atgggacccg aagcctacag 53101 atttgcgcaa agattatcgc tgtaatccta ttttgcttaa acttgattta ttaggacgtt 53161 tttcggttgc tgcaaattca gaatggttta cccaggcatt gaagctgata aacgaatata 53221 cggatgaaag cggtatatat cattttccta aaagttttct tactgagaaa gattccaact 53281 ggatattggg aagccatatg ggacttgggg aaaatcgcag acggaaagat gctttgacga 53341 tagaaggtac ttttagagca ttggtaataa tgaagaatat tttaaaggag atgtagagtt 53401 gaagacactg tttgtatctg atttggacgg gaccctttta agaagtgatg agactttgtc 53461 tcagtttact atcgatacaa ttaacggatt gacggaaaag ggtatgcttt tttcctatgc 53521 cacggcccgt tctttagtga cagcaaagaa ggttacaaaa ggactgaatt ctcatatccc 53581 ggtcattgta tacaacggta cgtttgtcat ggataatgtg acagaggaaa tattgattgc 53641 aaactacttt gacgatggga tttacgatgt gttttgcgat ttattcaagg aaggtatcta 53701 tccgattgta tactcttata ttgacgggat tgagaagttt tcttatattc ctgaaaaatg 53761 cacagaagga atgaaggtct tccttaatac gagaaaaggc gacaagagga ctaataaagt 53821 agggacaata gaggaattga cagcgggaaa gtgcttctat attacctgta ttgatgaacc 53881 ggaaaaattg gagccttttt ccaaaaaata caaggacaga tatcgtgtaa tctactcaaa 53941 agatgtctat tctgaatttc agtggcttga gataatgccc aaggcagcat ccaaggcaaa 54001 tgccattttg cagttaaagg aaagattggg gtgtgacaga atcgtatcct tcggagacgg 54061 tgaaaatgac attgatatgt ttaggatttc cgatgaagca tatgcggtgg ataatgcagt 54121 cgagagtttg aagaaagttg ccaccgggat tataggaagt aataatgacg atggtgtggc 54181 aaaatggctt cgtgcaaata tgggaaggtt gtaatgtgaa gaatgggtat tcttttcagg 54241 tactgaaaag aatacccatt cttacatatg tttcaagata ccatatagat ttcagatgcc 54301 gtacacattt cagatactat ttaatctcgt ctgtgcggta aataaacttg acattaccgt 54361 cagcgttttc gcttattccg gcaaaagact tgtaattctt tgatacggtt acggtagctt 54421 tcagccgttc gataagattt tcggcatcat cgaccgtatc gattaatttc tgaatacctt 54481 cttcatagaa ccttgaaagc ccgtctgaaa gctgcattgc tccgtcttta agctgtgtga 54541 taccgtctac gagtgcaggc agaccgtttt tcattgtcag tattccgtca taaagggagc 54601 aaacaccctt atataaagta cccgttccgt tctgcagttc atttgctccg tttttcaaat 54661 cagaagcacc gcttgccgcc tgggcgacac ctgcagtata cttcataagt ccaagataga 54721 atgaattgta gtcgtcaagg gaagttttga gcgcaataac tgattttgcc ccttccgatg 54781 ctgcagcaag ttttgattgc acttcttcac ttgccatgtt ttcggatatg actttttgta 54841 tctgtgcttc tgtattttgt tcaatcagtt gctgaatatc cttttctgcc atttttagct 54901 cagtattttt cttaatggta ttcttaattt cttctgtctg catctgttca tcgacttttt 54961 gcgaaatcat tgcggaaact tgctcgctct gcatttgttt gtcaatattt gatgagatta 55021 aatcggtaat ttctttactt gccattttgt tgtcaatggc ggatttgacg gccttttgtg 55081 ttgccgcatc cacgcgtccg gctgaaactg cggcataata gcttgccttg ttcatacctg 55141 ttgcagcaag aattacttgt tcttcaacgt tctcacgaac atttgcagtg accttttccg 55201 acacttgttc ttttactgct tttgtaacct ctgctttaac ctgttccgta actgcggcgg 55261 tgacattggc ttcgacttcc gaacgcacgg cttcaacgac ctgtgatttg atatagtccc 55321 gtttttcttc aacggctgct gtaacctgtt cgagagcctg attatatact tttgtactgt 55381 caagggattc aataatttca ttgagtactg aagcgtaatt ttcgatggtc aattcaggaa 55441 ctgtaagccc ggatgctttt aattgtgtct cggcggtgga aaggatagtt tcaaaaactt 55501 tttttgcacc gtcgtttaat gtatcattgt ttgccgaaag cgtatcaagg ccctgtgaca 55561 acgctgccgc tccggtatac agttttttcg ctccctcgtc aagggaatat gctccttctt 55621 tcagctttcc ggcaccctct gcaagttgat taattccttc aacaagttcc tttgacttgt 55681 caagaagcgt gcagatgccg ttgtacagcg aagaagaacc gtcaagaagt tttgtcatgg 55741 catcatcaag ttcattcatt gaatcggtca aatcagatat cgaatcaatt ttttccacat 55801 ctatattgtt aaataatgag ttggttgcta cagtaacggt aattcccaga gaaaaatcgg 55861 tggtatcggc tgttatctcc acataagacg gtatttcaaa cttttccttg tctattgcaa 55921 gattttcctg aagccccggt aaagcaaacc ctaaaactgc cgttttgttt ccatcgttaa 55981 tgatttttcc gtttgaaacc tgaacattgg taaagttgtc gttgtcaagg agcactcccg 56041 tcagcattac aaagggaacg tagatttttt catctttgcc gtttattttt acggtttcat 56101 attgcttgtt tttgtagtcg aagcggatgg ttactttgcc gcttttgcct atgagctcgt 56161 ctgcggatac tgtttttccg tcaagtttgt aagaaaccga aagatccacc ggcagttctt 56221 tttcaattgt gccctgataa tagatgtcat ttccctgcgc atcccataca cgggtgttgt 56281 tacctcccag ggtataactt tcgtcacctt tgatattttc tgtattttca agttcggtta 56341 catcagtgat tttttcactt gaaagcgtgt tttttatcca gtcgcttaca ataatttttt 56401 gcaccgtacc gtcagggttt gcaagaacat atactgtttc atctttgaaa gtatcgcttt 56461 ttgccgcagc ttcttcatgt tgtttttctg cagtgttttc cgtaatgttt tccgctgttt 56521 taacattttc agctttgtct ttacctgatg cgagggcgta agccgctccg ctggcaagga 56581 tggctataca caggcaaaga gaaatgattt ttatcatttt acttttcatt tactgacaac 56641 ctccaattca agttattatt aatctttgtc ataccaagag ttgttttgca aattattttg 56701 tcacagagga gcaagagtgc cggcagcacg aaaataacca tcagcatact gatgatggca 56761 ccacgggcca taagcataca catggagctg attatgtcaa tatcggaata aatggcaacg 56821 ccgaaagttg ctgcaaacaa ttccataccg gacacaatta ctgacggaat tgatgtggca 56881 agtgctgttt gtactgatgt tgttttgtca tttccctcaa tacgttccga cttgtatctt 56941 gtggtcatca aaatcgcata gtccactgtg gcgcccagct ggatggtgct gatacagata 57001 ggcgcgataa acggcagact ttgaccgaaa taatgcggca gcccgagatt gatgaatatt 57061 gcaagttcaa ttacggcaat cagaataaac ggcagggaaa tgctccttaa aaccaatgcg 57121 atgataacga agattgcaaa aattgacacc gtattgacga ctttgaaatc ctggtcagtg 57181 atttcaatca tatccttcat gcagggagct tctccgatga gcattccgtt tttgtcatac 57241 tttttcagta tggtgtttaa ctcgtcaatc tgcttgttta cgctgtcgct ggcaaccttg 57301 tattcagaac ttatgagcat aagtctccat ttatcacttt ttacaattga tgtaatcgac 57361 tccggcagaa tttcttccgg tacgcgggaa ccaataaccg actcaaggct tattacatat 57421 ttaactccgt ccacctgttc catttctttt atcatggagc gaacgtcttt ggacggtacg 57481 gaggtatcca caagaagcat gtgtgtagag gcaatgttaa agttttcccg aagcttggaa 57541 ttggcaatta catattgaat atcctccggc agacattccc ccatatcata atagacttca 57601 ctgtttgttt tgctgtaacc gtaatatgcc ggtgcgataa gaagcgcaaa aattataaga 57661 aacaggggaa atacttttac tatgcctttt gctgcctttt ccatgttggg aattaaggag 57721 cggtgttttg ttttttgcag cggtttgtcg agtatgagaa tgagagaggg aagcactgtt 57781 acagctccta taacaccgag aagcactcct tttgccatta caataccaag gtccagcccc 57841 atcgtgaaag acatgaagca aagggcaata aagcctgcta tggtggtggc cgaacttcct 57901 ataacacttg ccagtgtttt gttgattgca accgccattg catcttcttt gtcggtgtag 57961 gtttcgcatt gttcgttgta actgtgccac aggaaaatgg agtaatccat tgtaacggca 58021 agctgcaaaa ctgcggaaag tgcttttgtg atgtatgata tttcacctaa gaaaaagttg 58081 cttccgagat tgagcaaaat catcataccg atagatgcaa ggaacaccaa aggaacaagc 58141 cagctgtcaa ggaacaaaaa cattgcaata caggccagga ttacggctat tgtaacataa 58201 atcggttctt cacgttcgca aagttccttc aaatcggtta caagagccga caaaccggat 58261 acaaagcatt gtttgccgca gatagaacga atttctctta ttgcatccat tgtgacatcg 58321 gcagaggttg aagaatcgaa gaatactgcc attagcgttg cattttcagt gttaaatgca 58381 gaatagagtt tatttggcag catctccatt ggtattgaca aatctgcaat ggaatcatac 58441 caaataactg tgtctacatg ctcaactttg gaaatctttt ctttcaatgc cgcaacatct 58501 ttggcaggca tatcctccac gataacgagg gaaaaagcac ctttgccgaa atcattcatc 58561 agttcattct gaccgataac tgtttccata tcctccggca gatattcaag catgtcgtag 58621 tttactcttg tgccgatata tcccaatatg gacggaatca ttaaaagcag cgtcaatatc 58681 agaatcggca cacggaattt taccactgct tttccgaatt tcatttattt tcgccctccg 58741 tttcaaagta atcttcttca ataaagtcag ggtattgatg ttttatgatt tttaccgttg 58801 taaccgccac aaacagattc agaattcctt ctgtgataag cgttgcacca agaaggattg 58861 tcaggaccct ggcactttcg gacggcttga aaacaagaac ggctgtaaca attgcactca 58921 tgattgccag ggcgagaatt ccccaccatt ttttaatgcc gaactttcgg gaatcaaatg 58981 caatctgaat tttgaaaaga ctgtcggcca gcaaagctat gcccatagcc gcaaacagca 59041 ggctgattgc atccgatggc ttgagaagaa caataagccc cacaaccaaa acaagtattc 59101 caaattgcag gtcatattga aacgccaaac ggaacaagtc ctttgaaaaa tagcctgtaa 59161 gcttgataca gccaaacaaa accatgactg ctccgagcat ttttccgatt gttcgcattg 59221 atatgtccgg caggattata aataatatgc ctaatgaaag aagaacaacc gatataacga 59281 tgtagcctgt ttttgctatc cgcatcggta taacggaacg taccttcata gcccaaccct 59341 ccatttgtgg tcttattgga attataggtt atgcttcatg tccacaacaa cagacaaaaa 59401 aatgcccgtg cctgaaaatt gggcacggac aaaatttttg actaaaaatc agacaccgac 59461 ggcaaaatgc ctaaaattta ggcatatcag ggtcggtgtt gggatatatg ttatttgttt 59521 tcgatacatc tgcgaatcat ttcttcaagc atacccttct gcaattcgca tatgcggtga 59581 attttatcgt gaacatcgtc tttcattccg cttctgagcc agtcaatgac cattccgaaa 59641 cactgtgctt tgtaaaactg tattattata tcacggtctt cttctgaaac gggatgctct 59701 gcaaatacgg ttttgcagaa tgaaaccaca atataatcgc agaccttcca aagatattgc 59761 tcaaaaatgt cacggtttac ggatttgaaa atattcagta ttgcgcggcg gttctttttg 59821 gcaaaatcga ttgccgcgtt aaaactcatt tcaagagagt caagatttcg gtattcggca 59881 acaatgcggt ctgcctcttc tgttacaatt tcctcaatga gagatggaat atcgtgaaaa 59941 tgataataaa acgaatttcg gttaatgccg catttttcaa caatgtcttt gactgtaatc 60001 tgagagagcg ggcgttcgtt caataattct ataaaagtat ccttgattgc tttttttgta 60061 aaattcgcca tttacctcac ctctttgggg gtgtgtattt ccgcgatatc atcaagtctg 60121 taattttgta cttgtataag catttccggc attttagaat atcggtatta tactgcacta 60181 tttttatttt tgcaacatat ttatcaaatg cttttgtcag agttgaaaat agttgctgtt 60241 agtaatataa tataaacatg agttctgtta tgaaggtaga ggtgttttgc ttaaagcgta 60301 tacccaaagt aaaataaaat tgacattgat attgacttaa gcatcacttc tttttgtgtt 60361 ttgtccggtc atgagaaaac agaaaaccct aataagctaa aaccaggcta tttatccgga 60421 aaaattatcc cgacagacag atttgcagta aatacaacca attcagaatg ctttagtgtt 60481 taggttgaag gagttcaatt atataacagg aaggagatta ccgatgatat tatcagataa 60541 aacaatactt aaaatgttgg cagaaaaaac tttagttata gagccgttag agaaagagca 60601 gattcagcct gcaagcgtag atattcgttt ggggaacact ttcagtattg ttgaagattc 60661 gtgtaccggc ataataaatt tagaaaaaga agtaaagtat aaaacgatca caagcgacac 60721 atatatactt ttgccaaatc aatttgttct tgcaacaaca atggaatact ttgagctgcc 60781 aaacaatttg acggcttttg ttgaggggcg gagctcactg ggaagattgg gtttgtttat 60841 acagaatgca ggatgggttg acccgggttt taaaggagaa ataactcttg agctttttaa 60901 tgccaatcgc tgtgctattg aacttaaagc aggaagaaga gtcggtcaac ttgtttttgc 60961 taaaatggat gataccgctt taaatccgta caaaggaaaa tatcaaggtc aaagaggtgc 61021 tacgggttca agagttttcc tggattatga agtcaaatga agcattggct tattcctgcg 61081 gccttttaag tgactctgat ttggaaaata ttcaacaagt tgaagattat aaaggacaag 61141 gtaaaatctt ttgatgacct tgatgatata ttgcttgacg cacaattaaa tgaagaagaa 61201 tttactttac tgcttaatac tctcggagat gttgagcttg cggcaattat taaaaggcat 61261 tcttttgaat cgaatattca agctggtatt taaaaaatta tatgaaccga ctttcaaatg 61321 acagacgaga aaaaattctt caaattgcaa agtatctgaa attaaatcat aattgacaaa 61381 ttagtctata tgatatagac taatgttatg aagtctataa cgcatagacc agagagtaaa 61441 aggaggcgca gagatgggaa ggctgtttct cactgtttta aaaaggtttt gggtaattat 61501 tttatcagtt gccattgcga cagcagttgg tattggatta atggcaaatt cgaaagccga 61561 cgaatttggt gaatccggtc aaacttataa ttttgcgcaa caagatgata ctttattttc 61621 gccgcaaatt gaaaacaact acttttggga aaaagccagt aacaacaaga taattccttt 61681 cccggggtat ttaaaaaatg tcagttatag aatgcaatat gaaactaaag ccaggaactt 61741 gtctattagc aaagatacct ttgaaaagct gttttcactt atatccgagg ccggcaaagt 61801 gaaccctccg aagtctttta tagaagggta tgaactttta cttgaatatg aatctgaaga 61861 cggtctgtct tgtgatatag aacttattgg ctttaatgat gataagactc tttattttga 61921 aattagtagt acagaagaag agagttttat tgaaaacagc accggatata tagaatctgc 61981 ggaactggtt gcttttatta aatcaatcat aggatggaag gagtttgata tccaaaacct 62041 ttccggcact gatgagatat gtgtgcaagt tgtatcagga attgaaaaaa gcgataatgt 62101 tacaattatc tccggagcgg atgctgaata tataacaaac tccataatcc ggaattcaac 62161 aagaaaagat gcaggtaatt gtggctataa tataaagatt gtatttaaaa ataaagatag 62221 cagagaatat tgtggatttc tgacagggga tggatgcccg tatattgcaa tagaaggacg 62281 tgtcttccgc attgattcgg agatacttaa catgatatat gagaaaatca gttataatgt 62341 accattcggt gacaaagcta tccttccata gtactccaaa aagtaaatag ctatattgaa 62401 ggaggaagaa atcacacata taatataaac ataaagcatt atctatagga gtttggaaga 62461 ataattatga tggatgaaaa agctctaaaa ttacttaaaa aatatcatca tggccataaa 62521 tattcaaaca ggtcttatgg acgaagcagt tactcaggga ggttactata ctgatttaac 62581 tgaatatttt tcttctgtac cagaaattgc acgaccattc cttagaaacg caaaagttac 62641 attatccaag attgaagaga tgctttgcaa gggatttggc agagcgtttg gatttagtag 62701 acccatcacc agagaattat tggtcgaatt tataaactat cattttacta ttctcatata 62761 tcgtttcata ggaacggggc agagacgaag atactttgcg ccatttttcc ggagtgtatt 62821 tagtgaaatt ctatatagtt acattattaa tatataaata tctattggta atttggtcta 62881 tgcggtgtaa gcttatagtg taggtcgatg ttgtatagac caaggagtat tgtcattaat 62941 agaatataaa cttactttta aaagctttta tcggcagcca aaattgagca agtgtaagac 63001 tgtagatatt gattgagggg catggaagga gtagtaatga gtaaactgtt tcttactgtt 63061 ctgaatatga gccttactgc aagctatgtg atcctttttg tgataattgt aagactgctg 63121 cttaaaaaag ctcccaaatt tatctcctat gctctttggg gagtggtggc atttaggctt 63181 ataattcctt tttcttttga aagcatgttt agccttatgc ctggaaatac aaatcctgtc 63241 ctattccccc tgatataatt tatcagcaaa gtctgaaaat aaacagcggg atagaagcag 63301 ttgattcctt tgtaaacaat tcccttcctg caccggctgt agaagcaagt gtgaaccgcc 63361 ttcagattta tgtaaaaaaa ggatcataca tccgggcttt tggtataatt gcattgcttt 63421 aatcccaggt cttttgcaca ctttcggtta tagggccaat ggttctgaaa acagaagatt 63481 ctttgacttg actaaatatc aaaaaaattt ttaaggtaaa attctgatga aaacaaacat 63541 aaatagagag aaaatatgtt gttaagaata tttttacgga tattcagttt tataaacatt 63601 aaaaaagtgg taaaattgat aataacaaat aacaatcgaa agttgtttga gttgttgtga 63661 ctgattaagg agtgtattag gatgaacaaa gtaaaaatac tggccattgt cggttccctg 63721 aggaaaggat cctacaaccg gcagttggct ttggcagcaa aagaaatagt aaaggatacg 63781 gctgatttta cactgcttga ctatcaagac gtacctttaa tgaatgagga tattgaatat 63841 cccgcacctg acgctgtaaa gcgtgttcgt gaagaagtaa aggcggcgaa tggaatttgg 63901 ttttttacgc cggaatacaa tcactttttc ccgggagtct tgaaaaacct tattgactgg 63961 ttgtcccgtc cggttagtga gaatgagccc caggttcttg caggaaagcc cgctgcaata 64021 agcggaattt ccctgggtat gtcaggaacg gctattgcac aggaccatct ggttacgctt 64081 attagttttt tggacatgaa agttatgaac gttccaaggg ttaccgtacc caacgcctgg 64141 cagtatgttg acgatcaagg caaactcata atggaatcga tctatcccca tttggaaaaa 64201 caggcaaaag cttttgtgaa tttcatacag gcaaaatgct tataaagcag gattgcctgt 64261 atgttgtctc ctttcttttt tattttctct actgttttta tattcaaaat atagaatttt 64321 acatttttcg aatgaaataa aatttattgt gggcatgctt tttacaggat ttttgagggt 64381 ggtgattcta atcctatttg cagcatgccc acagtatttt ataataaatt aaattttgcc 64441 tgaaaattta tgcctgaaat ttatatgggt atttcactga tggctttcag caagtatctt 64501 ttcaaaattg tcaagtcagt ggagtcgacc ttgttgtccc tgtttaaatc tgccgctttt 64561 ttgaattttt cctcttgctc agatgtaccg agttccaaag atttgaggat atacctttta 64621 agcattaaca agtctgtaga attcactgca ttatcgaagt tcaaatctcc gtgttttatt 64681 gaaggagtcg gatcggaagt agcaccaatc agcttgatat tgtctacgac aaattttccc 64741 gacttgttgt tggcatacat gaagtgaatt gaatctatat tgtcaagatc caaagtaccg 64801 ctcatatcct gtcccggcgg ctgataatca agtcttcttc taaagctgga gaacggtatt 64861 tctatagttt tccacgaact gtcgggagtt attgagtaaa cccagtgttc tccgtctcca 64921 acaccgttta tgctcttttc ggcaatcata aatctgattt cattggcgga accgtcaacg 64981 gacttaatgt caaaagagat tttaagccat tttgaccaat cgccgtccgg taaactgtat 65041 actgttcccc agtagccgtc cgttgtcccg gtgtagctga cttccatgcc gtttcctgtt 65101 tttccggaca caatttttgt tgaaactttt gcaccttcac cggagtatga accccaattt 65161 aacacaccct caaaatcatc cagcattttt tcaccgacag ccggtgttac gggcggtttg 65221 gtcggtcttg gagttggtga aggtttcgga gaataagacg gatatgttcc gggattaaat 65281 aatgcattga ggatttcagt gtcaaaggta cgggtatctc tgttgtaaat agccatgtca 65341 ttatccaatg aaccaaaaac gccgttatcc catacggaac atgcaaaacc gcgctccagg 65401 gccgcatcac ttataaaatc ataccatttt acacgggaag ttctgtcggc ataagccatt 65461 acggcaaatt ctccaagata taccgggata ttgtttctgt cagaccaact cttaacaaaa 65521 tcaaatactc ttactacagt atccatgtct tcctgagtac cccatgtacc tctccacttg 65581 tgagtaaatt catatgggtc atagtaatgg aaagttccga ttaagtatgg gtcatcagga 65641 attttaatgt ttacaagcgt attataactg ttccaataac ctccgcctat tataacaata 65701 cgggttggat tggtctttct gattattttt aatattctgc tgttcatgtc gtctatttgt 65761 tcgtctgtaa tgttaccgaa aggctcattc atgatttcaa acagaagatt ttcggatttg 65821 tttttaaacc tttccgcaat ctgttcccat atcttttcaa accgttctat gtttccgtta 65881 tagtcttcct tgatccagtc atcatggtga gaatttataa ttgtaacaaa acctcttgaa 65941 agtgaccagt caaccacttg ctcaaccctg tccaaaaagg ctttgtcaat ggtatacggg 66001 tatgtcctca ttgtatggtt gtcccatctt acagggattc ttacgttttt atatcctgca 66061 gctttaaaat catcaaaata atattccatg gcagacttgg accaggagcc ttcataggga 66121 gcttcgagag tgtttccgag gtttgttccc atacccattt ttctaaccat ttcaaagggg 66181 tcgacagcct ttggtgagct tgatggtgga gcagaggtcc aagttggagt aggggtagga 66241 tttgatgaac cggctcctat tgcctccctg tatgctgcaa gggcttcagg acttgagttg 66301 attctccagt cggtttcttt gttctcgtga aaccatactg cagcaattac cttgttgtag 66361 gatgttctta tagagttata tgcttctgta atccatcttg ccttgtttcc gcctatttca 66421 gctgatgcaa actctgctat aatgatgggt ttgtttattg atgccaaagc ttggtaggct 66481 ctggagaaaa cctgatcaaa gctttgccat tggcttcccc agctttgagt ggtaccccag 66541 ttgtatccgt caattgaggt gtagtctaca taattgtctc cgggataatg acccagataa 66601 cttgtgccgt tacctacatt gtcgcagttt acattaaaca cccatttgac gttggtggct 66661 ccgttggcac ggaaaatatc gacaatatgt ctgaaagcgg ctatgtaagt ttcgtttgtg 66721 tttactcttg aagaatatcc tatggcccat ggataccagt ctccgttggc ttcatgaaga 66781 ggtcttaacc aaatttcctt gccataggct ttcatatctt gcgccattct ggttatgtaa 66841 gcatccgctt taccgttttt gatatctaca gtgttgtatt cccaaggttc ccaggtaatc 66901 attaatattg agccgttatt ataaacagcg tcggcataag gtcttaccca ggaaaaatca 66961 gttgaccagt taataaactg gtggacaata tcaagctttc taccctgaag ttcctgaaaa 67021 ctcttaattg ctgattctga cggctgggtt cccacccaag caccgatttt taaaccactg 67081 ttgtaattac caagcgactg aaaagaaagt aatcctacaa ttatgcttaa caccaaaaaa 67141 gaaactaaaa gccttttttt cataatgtcc ctccctttag aaaactttaa aaagacaaaa 67201 ttttaattaa tttaaattgt tcttaaatgc cggttgttaa agtatatcct cctttcccaa 67261 tggtattttg tcaaaaatgg cattttaaat tttgggttta aataattttc ccctctacta 67321 attaatactt tctgaaagta taaaggtaac gttttgtaga aagtaacatt ttataaaaac 67381 aaaaatgccg gatattttta aataaccggc aggagaaaat caataatgct tttctatttc 67441 caaaaatttt gcaatgtttc aagaatgggc tgattgtcca gtattgaaat ttttttcagg 67501 tttttacctt taaggtaata ctctttaagt gcttcatcaa aatgattttc ttttgcggat 67561 gtggcaacgt gttcatttac aaagtaaaag ggattcaggc cgatttcact atcccagctg 67621 acatattctc cgtataaagc gttaaaaccg gttttcacat ttataaaagc acctacggca 67681 tttttatatt ggaagtatga agccgagata ccgtatttat caaagatgtc gtgaacggtt 67741 tcaagccatt gtacacgttt gtctacgctg tttacccggg agattccgta ttcggtaaga 67801 agcggagccc tgccgacatt tttagcccat tcataacgtt ttctgacttg agcttcaagg 67861 ctttcggcat caaaatctcc gacaccgtca ttgacaaagt tgtatggttc gaaaaagtgg 67921 aacaagtata ctacgtttga tgaatcaact tttaccaaac ctctttccca gataatacct 67981 tgctcaccgt tgtctattac ataactattt gttttttcgt tccagtagga ttcgccggga 68041 ttggcctctc tgctgttata ttcgggaaca aatatgatat gatttttgtc aattttacgt 68101 atttctctgc atacattgtt caggcgttcc ctgaatatcc cgattccacc ttcactttca 68161 ctcggggctc ttggctggtt tataagtcca tatcctgcca cacctttaaa gtctttaagt 68221 tcttcggcca aatacttcca catctcaacc cactgttcgt agtaggtatc atcctcaaac 68281 acagatttta tacgttctga gccgtgtttg tacttttcgt aggcgtcatt gatcgaatcc 68341 agtcccggag gagccattag cataacagcc gtatatatgt ccattgagga aaaacgcctt 68401 atatgttctt tgagcttttt gagattttct tccctgtttg gattgtcttc tgcaaaaagc 68461 tggtaattga tatcatataa aaccgtgttg cagcccaggt ctttaatacg ctcaaaatca 68521 tcatcagtga gcacccaggc atcctgtaca agagggcgta taatagggtc cataccttga 68581 ctttgcaatt tttccgattc tccgttgacc cagttgcccc aaaagttgtt tgtaagggta 68641 acacctctta tgtggaagat ttcaccggta ccggtaacaa tattctgacc gtctgtacgc 68701 aaaaaggtca ggtttgttgt ttcaccggta ttggagcggt tattgctgct tttggcaatc 68761 cagttgccga gattgtcaaa aattccgccg gttattaaca aagctactgc cacaaagact 68821 gccaaagttc ccaaagacgc tttaaaagca ggctttagcc tttccaatga agacagaatc 68881 ttaaaagtca gtttcgattt cttgtatctg tcagggtcta tggcattgat aacccgcatg 68941 taaaaatatt tatccatttc cggttctttg gcaatatatt ttttggatat cataagtgca 69001 cccagataat ttctgcagtc catgcaggtg cttatatgtt tgtttatttt ttcggatttt 69061 tcattaggca aagagtccaa ctcacagttt attaaataat ccatatatct gcatttcatt 69121 cgaaatcacc ttcctttctc atgcccgcga tctttttggc aagtatggat tttgccctgt 69181 gaactttcat tttggcggct tcctgggaga tacccataat ttttccgatt tctttatagg 69241 aaaagtccct tatgtatctt aatataaaag ccgttttttg tttttctttc agactatcga 69301 taatctcaat tatttctttg taatgttcct tgacttctat cagtagttcc gggctgtcgt 69361 caaagcttgg gatttcttca atgaaatcat ctatgttaca gccggaaggc ctgagtttct 69421 tttttttcaa tgatgatttt attgtattga gagtaatgct gtaaatccac gtggaaaagc 69481 ggtaattatt attatatttg tacaagttgt tgtatacttt tacaaataca tcttgcagga 69541 tgtcttccgt gtcttctttt gattttgtca ttttatatat aaagttgtac agttgtccct 69601 gataggcttg tacaagcaaa gcaaacgact gtatgtcacc gtttaatgtg ttggatatta 69661 aagtgctctc atccagcaat ttatcaactc ccttgtaaag aaaaagtaca aaactcaatt 69721 taattaataa catatgggaa aacaggcaaa tatttggagt agaaaataac agagtgactt 69781 acaaaagaaa attcgagtat ccaatctgat tatatcatta aaatatggat aaatcaaatt 69841 ctctgtatat gtggcaaaaa aatattataa actccgctgt aaaaaacgtt acttttttaa 69901 gagctcggaa gtattactta ttagacagga agattaagaa ctattagtgt aattaatgtg 69961 ttttgaaaaa aagagaaggt gatttattag agagagaaat ggtatttgga gtaaaaagag 70021 tgattatgat tagtgattat aattaataaa gaaaattcga gtattcaatg tatgttttgc 70081 aatctgttga cgttggtaca gattttcagg tctcaaaata attatgcttt tgccggaatg 70141 tgtataacaa aggtagcata attgcaattt ctgggttatg tgtactgtga ccgggctata 70201 gtataattat tttgaggtga tgataatgat ttttttctga aaaattgcga aataaagata 70261 tacgagtgct atttccgtgg agaattaatt tgttaaagtt gaaaaatata taaaagcata 70321 aatccttgat tggatttatg ctttttcatg cctttttata atctgcgtag agattttcaa 70381 ttgacctgtc ataagttttt tccccggctt tggagaagaa acatcccggt acttccccca 70441 ttctgcggtg atatgcaaca cattgacagc atttaccatg gcgcgaacat gatgtatatg 70501 tgcaagtgca attgatagta ttatcgcagg ccattttaac ccctccaaaa taaaaaatga 70561 cataaacatt ataataaaag acgggctctg tttcaagaga gaacaaaatt aacaagtaaa 70621 accggattca cttatggaac ttgtcattgt tttacctccc caggttacct gtcgggctta 70681 tgatgaattt gatgaaagct gcattgaaaa atgcgataac ggatggtttc gtgtaacggc 70741 aaaagtggcg gaggataact ggttatacag ctttttaagg tcattgggaa aagatgtttg 70801 tattataagt ccggagcact taaaagaaaa atttaaacaa gaagatataa aaacattata 70861 atatgacaca ctgttgtcat ctttccgatg ttattatata agaagaaagc tattgagaac 70921 acaatggcag gactgtatag cgcgggcaaa cgacagaaat gggaggagtg tgaaataata 70981 tgccaagacc tgcaacgaaa gaagatttaa ttactgccgc aaacgagcaa tttgacaaga 71041 tgtgggcact tatcgacagt atgacggagg aagagctggc catgcccttt gattttggtg 71101 atgatccgaa agacaaggag gctcactgga aacgtgataa aaatctgcgg gatattctca 71161 ttcacctata tgagtggcat cagcttttgt taaattgggt tacttccaac cggaagggta 71221 attccgtccc ttttttgcct gaaccgtata cttggaaaac atatggcgat ctgaacatga 71281 aattttgggt gaaacatcaa tccacaccgt atgaagatgc aaagaaaatg cttttgcaaa 71341 gccataagga agtgcttgca cttatcgagg ggttttccaa cgaggagctg tttgaaaaac 71401 agtattttaa atggacagga acgacaagtc ttggcagtta ctgtgtcagc gcaacaagca 71461 gccattacga ctgggcgatt aaaaagataa aacggcagat aaaaaagctg cgttcccgtt 71521 catgacaggg aagggagctt taagaagcaa ggattctgta ttcggcatat cagtaaagca 71581 ttccaaaggg actgccacgc agttttaaaa tgatatggat tgtggatcaa gcaaaaaagc 71641 tcatatatcg aaaatataca gttgatacat gggtttgaac gtaaatctga tttagagtta 71701 tgttatacat ttttggtggt atatttttgt tttgaaaggt aattaacaaa agtataccat 71761 ttttaaaata aagggaggat aaaatatgtt ggaagtagga acaaaagcac cggattttga 71821 attgccggat cagaacggta aaatgcacaa attatcagat tatagaggca agaaagtaat 71881 tctttatttt tattccaagg ataacactgc aggatgtacc aagcaggcat gcggttattc 71941 ggagagatat cctcagtttg tagaaaaggg tgcggtagtt cttggtgtga gcaaggatac 72001 tgtggcttct cataagaaat tcgaagaaaa acatgggctg gcgattacgc ttctttcaga 72061 cccggaacgt aaagcgattg aggcttatga cgtatggaag gaaaagaagg tttgcggaaa 72121 agtttgtatg ggcgttgtca ggaccacata tcttatagat gaagagggga ttattgtcaa 72181 ggcaaacgat aaagtaaagg ccgaagatga tgccgagaga atgctggctg agttataaaa 72241 agattatttt gttggttgat agaaagctaa ttgatatcta ctaaaaaata attggatgta 72301 aattgtctga tgggcaagtt aacggtgaaa catagcaatc cggaaggatt atttaataaa 72361 ggcttacagc caggttgtta cagtcagcgg taatgggaag acgatttata tcggtggaca 72421 aaatgctatc aattccgaag gccaattggt aggaggggac aattttgagc ttcaaacaaa 72481 acaagctttg gagaatatta aaattgcttt ggcttctgaa aatgcaactt ttaatgatgt 72541 tataaagctc aatatttaca tggtggacgg gtgtgacccg gctatagggt ttaaagcatt 72601 tatggaaacg gttggcaagc ttgaaaagcc tcctttgata acggttctcg aggttgcagg 72661 tcttgccaat catttgtgtt tgattgaaat tgatgccatt gccgtagtgg aagaaaagga 72721 agattgaaaa agctgatgca agtggcaaaa tagattgatt tcacaccata tttgatgtaa 72781 aatataattg caaatacatc gaatatgatg tataaaccta taaagtagga gaaatgacat 72841 gaatgtatac cattatgaaa caagtggagg caaagattta atccttgagt atattgatgg 72901 gcttccgaag aatgaaaaag cagaaggatt aacaatcctt gagaaacttg aaaaggaagg 72961 actggaagca cttgaggtac tgaacacaag acaactgaga ggaaagctct gggaaatcaa 73021 gttttatcgt tctaaccgca taatgtacgt tgtagcagat gaagataata tatatttagt 73081 gcatgcttgt aagaaacaaa aaggtaaagc tgagaagttt gagttggata cggcaataaa 73141 gagagttaaa gagcttgaaa aagaactagg taaaaaattt atttgatgaa tgaaataaga 73201 ggtgaatata tatgccgttt aaaaaggtta acgtgaaaga tgaaattaat aaaagattgg 73261 aaaatgatgc ggagcttaaa aaagcttatg actgtgcaca acttgagtat gaagtgctta 73321 agcagcttgt taaaatgaga aaggaaatgg gcttttctca aagtgatgtt gcaaaaaaat 73381 ccggattaac acagcaaatg gtttcccgga ttgaaaccgt aggaaactct cctactctaa 73441 gaaactttat aaagtatgta gacagtttgg gtttggaaat aaaacttgag aaaaagaata 73501 ccgatgttga gtacagtaaa atgtagatgg ctataccgcg caatttgagc agttttaaga 73561 ttgggcagca acgagagaat gtcgttttta atataaggca ttctcttttt tatacttata 73621 tattatatgc aaaaaattat atattattat aaataaaaaa atattagtca ataacaaact 73681 caagatgtca taatatgagc aaaattattt atataaaata ttattaatac cgttgctgct 73741 tttggacgat aaaataataa ataagaatac aatcggcaga aaaaggtatt aacaaccttt 73801 ctctgccgat ttgttaaaaa ttgt //