LOCUS NZ_ACVX01000018 69706 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00030, whole genome shotgun sequence. ACCESSION NZ_ACVX01000018 NZ_ACVX00000000 VERSION NZ_ACVX01000018.1 GI:256004756 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 69706) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 69706) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000018. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..69706 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene complement(658..1404) /locus_tag="ClothDRAFT_1593" CDS complement(658..1404) /locus_tag="ClothDRAFT_1593" /inference="protein motif:PFAM:PF07685" /note="PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: gsu:GSU2992 cobyric acid synthase" /codon_start=1 /transl_table=11 /product="CobB/CobQ domain protein glutamine amidotransferase" /protein_id="ZP_05429732.1" /db_xref="GI:256004757" /db_xref="InterPro:IPR011698" /translation="MYELNICHLYPDLLNLYGDRGNIMALKMRCVWRGINVNVSNISI GDKFDAEAYDIIFLGGGQDYEQEIIQDDLLNQKGEEIRNAVKNDKVFLAICGGYQLLG SYYKTWDGKEIHFLNALDLWTIGGKERMIGNFVFECDFLKNDHYDGKIVGFENHSGRT YLGPGVKPLGKIIKGYGNNGEDGFEGAIYKNVYCSYSHGSLLPKNPALADHLISVALK QKYKDFVSLSGIDDEFENLAHDTTIKRIMG" misc_feature complement(766..1371) /locus_tag="ClothDRAFT_1593" /note="Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750" /db_xref="CDD:153221" misc_feature complement(order(931..933,937..939,1120..1122)) /locus_tag="ClothDRAFT_1593" /note="catalytic triad; other site" /db_xref="CDD:153221" gene complement(1406..2809) /locus_tag="ClothDRAFT_1594" CDS complement(1406..2809) /locus_tag="ClothDRAFT_1594" /inference="protein motif:PFAM:PF08353" /note="PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; KEGG: gur:Gura_3978 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1727" /protein_id="ZP_05429733.1" /db_xref="GI:256004758" /db_xref="InterPro:IPR013221" /db_xref="InterPro:IPR013564" /translation="MNIRLIFTIIVTKLLILALRILKRGGTSLPGKVAYKIYPDIIKV ISKDFKIIMVTGTNGKTTTTRIIGKVLEENNIEYITNKSGANLVSGIITTFIESVNIF GKSKTSTALLEVDEAAFNVVTDYVQPDVLVVTNFFRDQLDRYGELYTTVSNVRSGIEK SPNVKLVLNADDSLCASLGHNMDREAIYYGFSEEAYNNSSTVVNSDASICLYCKSKYE YSYNVYGHLGGFSCPNCGYMRPDSKVTCVKINELNTSYSDIIFSLSPIKGNDEPVSYN ARINLPGLYNIYNALAAASLGHLSGFSPESLVKAMESFECGFGRMETIETDGKTIKVI LVKNPTGFNQVLSYLLTEKQNTQIAFVINDRLADGTDISWLWDVDFEQLQQMQDKVSS FYASGIRAEDMAVRLKYAGINIDKIQIEKDYEELLNKALATTSEGQNLYILPTYTAML EVRSLLEKKFGLKEFWK" misc_feature complement(1409..2725) /locus_tag="ClothDRAFT_1594" /note="UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769" /db_xref="CDD:31112" misc_feature complement(<2204..>2434) /locus_tag="ClothDRAFT_1594" /note="Mur ligase middle domain; Region: Mur_ligase_M; pfam08245" /db_xref="CDD:149357" misc_feature complement(1463..1807) /locus_tag="ClothDRAFT_1594" /note="Domain of unknown function (DUF1727); Region: DUF1727; pfam08353" /db_xref="CDD:149422" gene 3138..3989 /locus_tag="ClothDRAFT_1595" CDS 3138..3989 /locus_tag="ClothDRAFT_1595" /EC_number="2.5.1.7" /inference="protein motif:PRIAM:2.5.1.7" /note="PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: gsu:GSU3102 UDP-N-acetylglucosamine 1-carboxyvinyltransferase" /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine 1-carboxyvinyltransferase" /protein_id="ZP_05429734.1" /db_xref="GI:256004759" /db_xref="InterPro:IPR001986" /translation="MHDAHHGFLYCEVDKIKGCEIQLDFPSVGATENIMLAAVFAEGE TVIRHAAKEPEIVDLQNFLVGMGADVSGAGTSTITIRGTNRKLNNVEHTVIPDRIVAG TYLVAAGITGGELNLKNVMPEHITSVVSYLRESGCRINIKRNNIHISGPSRPKAIDII RTLPYPGFPTDMQSQFVSLLSVARGTSIIVETIFENRYKHVEELLRMGADIKLEGRLA VIKGVKRLTGATVTARDLRGGAALVLAALAAEGTSIISGIKHIDRGYENIEGKLSMVG AIIKREE" misc_feature <3153..3962 /locus_tag="ClothDRAFT_1595" /note="This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats with a...; Region: EPT_RTPC-like; cl00288" /db_xref="CDD:185884" misc_feature order(3441..3443,3657..3659,3846..3848,3927..3929) /locus_tag="ClothDRAFT_1595" /note="putative active site; other site" /db_xref="CDD:73274" gene 4101..4862 /locus_tag="ClothDRAFT_1596" CDS 4101..4862 /locus_tag="ClothDRAFT_1596" /inference="protein motif:PFAM:PF08478" /note="PFAM: Polypeptide-transport-associated domain protein FtsQ-type; KEGG: sfu:Sfum_3472 polypeptide-transport-associated domain protein, FtsQ-type" /codon_start=1 /transl_table=11 /product="Polypeptide-transport-associated domain protein FtsQ-type" /protein_id="ZP_05429735.1" /db_xref="GI:256004760" /db_xref="InterPro:IPR013685" /translation="MISGIFAAILVCVGLSPLFSVNRIEVYGNKHYNSNEVIEASGLV IGNNWFKSNSVNLKGILTFRSIDAENLLLNRCPYLKSAIVKIDFTGVVRIEVTERDPV ALVPYMGANLVIDNECFVLALSSNAEDEKLPVIKGVDCEGYTLGQALPTHNPKCLEAF RRVMKVIESADSNSGERGKEYGIKGIINYIDVSDLDNIKLYLDSRILVNLGNYKDISE YRINFLREIFYFQLTKEDKGLLDFASGEYPSFIPD" misc_feature 4101..4733 /locus_tag="ClothDRAFT_1596" /note="Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589" /db_xref="CDD:31777" sig_peptide 4101..4163 /locus_tag="ClothDRAFT_1596" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.654) with cleavage site probability 0.554 at residue 21" misc_feature 4161..4397 /locus_tag="ClothDRAFT_1596" /note="POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478" /db_xref="CDD:149506" gene 4878..5255 /locus_tag="ClothDRAFT_1597" CDS 4878..5255 /locus_tag="ClothDRAFT_1597" /inference="protein motif:PFAM:PF06947" /note="PFAM: protein of unknown function DUF1290" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1290" /protein_id="ZP_05429736.1" /db_xref="GI:256004761" /db_xref="InterPro:IPR009709" /translation="MIPLFGLIIGILIGIFIPYSIPEQYSSYVAVAILAALDSVFGGI VSTIQKKFDMGIFLSGFFGNALLAAALTYIGDKLGIQIYFAAIFAFGNRLFLNFAVIR RFLLNKLTKKDNIKDNMMETKEA" misc_feature 4932..5198 /locus_tag="ClothDRAFT_1597" /note="Protein of unknown function (DUF1290); Region: DUF1290; cl01587" /db_xref="CDD:154487" gene 5418..6659 /locus_tag="ClothDRAFT_1598" CDS 5418..6659 /locus_tag="ClothDRAFT_1598" /inference="protein motif:TFAM:TIGR01174" /note="TIGRFAM: cell division protein FtsA; PFAM: cell division protein FtsA; KEGG: dal:Dalk_3127 cell division protein FtsA" /codon_start=1 /transl_table=11 /product="cell division protein FtsA" /protein_id="ZP_05429737.1" /db_xref="GI:256004762" /db_xref="InterPro:IPR003494" /translation="MDDIISCIDIGTTKVCAIVAKLDENGNVEILGRATEPCSGVKKG VIVDIDSVSNALKSCAQKIRALLNIDIENVYVNVMGSHVDVFFNKAAVDILRPDRQIT SEDVERTLKKVEDVKLPDNVQIIDVIPRQYIVDGCDEIVDPVGMAGVKLELEADVVVG KITTFNNIIKSLDNANIKVNGFIAEALAVGDLVLSPEEKDIGAILIDVGGGVTNISVF KNKCLALYDSIPVGGDHITNDISIGLKVSLNDAEKLKRDYGLALTSLIDNDHDITINE FSENTKRTIKVSEVVEIIEARVQEIFSLCKERLEQEGILNGFNGGIVLAGGGISYIDG SVQSAKEIFGLPVRIVSYKALEIKNAEHVTAMATVKYVANRIKSEAKGGGTKNNKPGK QKQKKEYGFLKKIASFFHGLF" misc_feature 5418..6656 /locus_tag="ClothDRAFT_1598" /note="Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849" /db_xref="CDD:31190" misc_feature 5430..5996 /locus_tag="ClothDRAFT_1598" /note="Cell division protein FtsA; Region: FtsA; cl11496" /db_xref="CDD:159497" misc_feature 6024..6452 /locus_tag="ClothDRAFT_1598" /note="Cell division protein FtsA; Region: FtsA; cl11496" /db_xref="CDD:159497" gene 6985..8079 /locus_tag="ClothDRAFT_1599" CDS 6985..8079 /locus_tag="ClothDRAFT_1599" /inference="protein motif:TFAM:TIGR00065" /note="TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ domain protein; KEGG: ftsZ2-2; FtsZ2-2 plastid division protein" /codon_start=1 /transl_table=11 /product="cell division protein FtsZ" /protein_id="ZP_05429738.1" /db_xref="GI:256004763" /db_xref="InterPro:IPR000158" /db_xref="InterPro:IPR003008" /db_xref="InterPro:IPR008280" /translation="MLEFDIDMEQFAQIRVVGVGGGGNNAVNRMIDAGLRGVEFIAIN TDKQALYLSKANTKIQIGDKLTKGLGAGANPEIGEKAANESRDEIAQAIKGADMVFVT AGMGGGTGTGAAPVVAEIAKEMGILTVGVVTKPFMFEGRKRMQHAERGIENLKNTVDT LVTIPNDRLLQVAEKKTSIVDAFRIADDVLRQGVQGISDLIAVPGLVNLDFADVKTIM QNTGLAHMGIGRASGDNRAEEAARQAIQSPLLETSIEGARGVLLNITGGADLGLFEVN TAAELVQKSADPDANIIFGAVIDENLKDEILITVIATGFDKVPSIRKSDKSAVADKAP SATSGEKASASQFGADELEIPTFLRRNRFK" misc_feature 6985..8070 /locus_tag="ClothDRAFT_1599" /note="cell division protein FtsZ; Validated; Region: PRK09330" /db_xref="CDD:181781" misc_feature 7069..7926 /locus_tag="ClothDRAFT_1599" /note="FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum...; Region: FtsZ_type1; cd02201" /db_xref="CDD:100021" misc_feature order(7129..7131,7294..7314,7387..7392,7411..7413, 7480..7482,7531..7533,7540..7545,7552..7554) /locus_tag="ClothDRAFT_1599" /note="nucleotide binding site; other site" /db_xref="CDD:100021" misc_feature order(7603..7608,7612..7614,7789..7800,7807..7809) /locus_tag="ClothDRAFT_1599" /note="SulA interaction site; other site" /db_xref="CDD:100021" gene 8315..9208 /locus_tag="ClothDRAFT_1600" CDS 8315..9208 /locus_tag="ClothDRAFT_1600" /inference="protein motif:TFAM:TIGR02854" /note="TIGRFAM: sigma-E processing peptidase SpoIIGA; PFAM: peptidase U4 sporulation factor SpoIIGA" /codon_start=1 /transl_table=11 /product="sigma-E processing peptidase SpoIIGA" /protein_id="ZP_05429739.1" /db_xref="GI:256004764" /db_xref="InterPro:IPR005081" /translation="MKVYIDVLVMENIVMNYLILLLTAKFMRHKPSHLRLFLGALAGA AYVVVLLLMPNLKVYCTTLAKFALSLLIVAIAFSPAKPALFIKTLAVFYVSTFIFAGA AFAFLYLNQTGGFVRNGIVYIWNSKGTTLFFAVATVGIIIRIFWDIVQQRISKEKLLM PLKIAFGNGTIELFALVDTGNSLCDPLTNSPVVVVEFNAIKNILPMEIQRIFDESKEN DLDSVTKIVSDSKWMSRFRLIPFTSLGKENGMLIGFRPDYIEVGENAEKKGITDVIIG IYNRALSKNNNYSALLSPELI" misc_feature 8315..9205 /locus_tag="ClothDRAFT_1600" /note="Sporulation factor SpoIIGA; Region: Peptidase_U4; cl04058" /db_xref="CDD:155847" gene 9261..9995 /locus_tag="ClothDRAFT_1601" CDS 9261..9995 /locus_tag="ClothDRAFT_1601" /inference="protein motif:TFAM:TIGR02835" /note="TIGRFAM: RNA polymerase sigma-E factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ppr:PBPRB0960 DNA-directed RNA polymerase sigma factor" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma 28 subunit, SigE" /protein_id="ZP_05429740.1" /db_xref="GI:256004765" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR014200" /db_xref="InterPro:IPR014284" /translation="MFFLKKLKLSLMVGYINLLNKLKLYNNYPVYYIGGSEALPPPLT NDEENYLLSKLEKRDFGVKSILIERNLRLVVYIARKFENTGVGVEDLVSIGTIGLIKA INTFDPNKNIKLATYASRCIENEILMYLRRNNRMKTEISIDEPLNVDWDGNELLLSDI LGTENDLIHRSIEDEIDKELLAMAMKKLSVREKKIMELRFGLTNGGVEKTQKEVADML GISQSYISRLEKKIISRLRKEISRMV" misc_feature 9345..9992 /locus_tag="ClothDRAFT_1601" /note="sporulation sigma factor SigE; Reviewed; Region: PRK08301" /db_xref="CDD:181367" misc_feature 9456..9668 /locus_tag="ClothDRAFT_1601" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature 9792..9971 /locus_tag="ClothDRAFT_1601" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cd06171" /db_xref="CDD:100119" misc_feature order(9825..9827,9855..9857,9888..9893,9921..9923, 9927..9932,9936..9944,9948..9953,9957..9959) /locus_tag="ClothDRAFT_1601" /note="DNA binding residues" /db_xref="CDD:100119" gene 10156..10929 /locus_tag="ClothDRAFT_1602" CDS 10156..10929 /locus_tag="ClothDRAFT_1602" /inference="protein motif:TFAM:TIGR02850" /note="TIGRFAM: RNA polymerase sigma-G factor; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: abu:Abu_1011 RNA polymerase sigma factor RpoD" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma 28 subunit, SigG" /protein_id="ZP_05429741.1" /db_xref="GI:256004766" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR014212" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014322" /translation="MLVNKVEICGVNTSKLPVLTNEQKKELFERMHKGDTSAREEFIK GNLRLVLSVIQRFNNRGEYVDDLFQVGCIGLIKAIDNFDVTQNVKFSTYAVPMIIGEI RRYLRDNNAIRVSRSLRDIAYKALQAKEKLTNQNSKEPTIEEIAKELGLPKEEVVFAL DAIQDPISLFESVYHDGGDAIYVMDQVKDEKNNDENWLEGIALSEAMRKLNDREKLIL NLRFFDGRTQMEVAEEIGISQAQVSRLEKTALMHMRKYI" misc_feature 10156..10926 /locus_tag="ClothDRAFT_1602" /note="sporulation sigma factor SigG; Reviewed; Region: PRK08215" /db_xref="CDD:181296" misc_feature 10279..10491 /locus_tag="ClothDRAFT_1602" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature 10525..>10662 /locus_tag="ClothDRAFT_1602" /note="Sigma-70 region 3; Region: Sigma70_r3; pfam04539" /db_xref="CDD:146934" misc_feature 10756..10917 /locus_tag="ClothDRAFT_1602" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cd06171" /db_xref="CDD:100119" misc_feature order(10786..10788,10816..10818,10834..10839,10867..10869, 10873..10878,10882..10890,10894..10899,10903..10905) /locus_tag="ClothDRAFT_1602" /note="DNA binding residues" /db_xref="CDD:100119" gene 11186..11446 /locus_tag="ClothDRAFT_1603" CDS 11186..11446 /locus_tag="ClothDRAFT_1603" /inference="protein motif:TFAM:TIGR02888" /note="TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain protein" /codon_start=1 /transl_table=11 /product="sporulation protein, YlmC/YmxH family" /protein_id="ZP_05429742.1" /db_xref="GI:256004767" /db_xref="InterPro:IPR007903" /db_xref="InterPro:IPR014238" /translation="MNRTSDFREKEVINIKDGRRLGFVSDVEINLQSGRIEAIVIPSG GRLLGLIGRDNECVIPWEKIKKIGEDIILVEMDDRFIRKHFE" misc_feature 11192..11410 /locus_tag="ClothDRAFT_1603" /note="Photosynthetic reaction center (RC) complex, subunit H; RC is an integral membrane protein-pigment complex which catalyzes light-induced reduction of ubiquinone to ubiquinol, generating a transmembrane electrochemical gradient of protons used to...; Region: PRCH; cl09959" /db_xref="CDD:164180" gene 11594..12049 /locus_tag="ClothDRAFT_1604" CDS 11594..12049 /locus_tag="ClothDRAFT_1604" /inference="protein motif:PFAM:PF03477" /note="PFAM: ATP-cone domain protein; KEGG: pca:Pcar_1444 transcriptional regulator NrdR" /codon_start=1 /transl_table=11 /product="ATP-cone domain protein" /protein_id="ZP_05429743.1" /db_xref="GI:256004768" /db_xref="InterPro:IPR003796" /db_xref="InterPro:IPR005144" /translation="MKCPYCGYIEDRVIDSRPTDEGSAIRRRRECSKCLKRFTTYEKV ESLPIMVIKKDKSRQAFDREKLLNGILRACEKRPVSIEQLEKLVDDIESQIHNSLQRE VTSKDIGEMVMAKLKNLDEVAYVRFASVYRQFKDINTFMDELRKLLNEK" misc_feature 11594..12046 /locus_tag="ClothDRAFT_1604" /note="transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464" /db_xref="CDD:179038" misc_feature 11738..12004 /locus_tag="ClothDRAFT_1604" /note="ATP cone domain; Region: ATP-cone; pfam03477" /db_xref="CDD:146230" gene 12105..13976 /locus_tag="ClothDRAFT_1605" CDS 12105..13976 /locus_tag="ClothDRAFT_1605" /inference="protein motif:PFAM:PF01973" /note="PFAM: protein of unknown function DUF115; KEGG: dal:Dalk_0641 protein of unknown function DUF115" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF115" /protein_id="ZP_05429744.1" /db_xref="GI:256004769" /db_xref="InterPro:IPR002826" /translation="MNEVLAKNLSLLKEYQPETYLKLDRYIKGEYVPKDNSVEKILLA RQDDLIINILVKCSDKDFLLCDHENPINEAYAWIDKYIDPSNKADIVFGMGLAFHLEV LLTSFPNKKVIVIEPNINLFYQIACIRNLEPVIKKAEIIVDEDLDVILERINSLFWDT EKGGIQVQPLEVYGEMFPEMWDKLRDSFIKLANNFTVDIATRRKFGELWVHNNIKNLN KICEASNAGVLVGKFKGIPGILVSAGPSLEKNIHLLKGLEDKCVIMAAGTAVRIMEDF GLAPHFMVGIDAGAKEGEIHSNVKNKDIYFIYSNQVSTYSVDGYKGPKFVMNYPIDMY TAGFFEYAGIKSDFFLSGPSVANTCFDILFKMGCDPIIIIGQDMAFTYGSMYAGEVPG TVVDGAGEAKRRGYVLAKDIYGNEVYTTRPFLAMRNWFEGYFEKVRDKTTIINATEGG LNISYARNETLEAALKSCNLSESGIKDHIRSLHEEGKFADTVASKIEEYRAYVQREIR RLEQLSKRQLETAEDLKRDVYHPSKSRSRFIKAVNSINEMSDRVLQSPIYNSLLKNLV EIDFYIIKAEVDRLVKILTKYDDIKNVYVNAILSQNQKLNASLGKIKKFFDESDVTA" misc_feature 12240..13910 /locus_tag="ClothDRAFT_1605" /note="Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604" /db_xref="CDD:32596" gene 14044..14835 /locus_tag="ClothDRAFT_1606" CDS 14044..14835 /locus_tag="ClothDRAFT_1606" /inference="protein motif:PFAM:PF00963" /note="PFAM: cellulosome anchoring protein cohesin region" /codon_start=1 /transl_table=11 /product="cellulosome anchoring protein cohesin region" /protein_id="ZP_05429745.1" /db_xref="GI:256004770" /db_xref="InterPro:IPR002102" /translation="MNGVHMMKKWLCILVIVVLASTCLIAYAAEANQWTALRATFKVF VKGEEFKSQDPIVAINGRTYLPLKAIGDVLGVDVVWNEGLRRVEVAMSENQNGDKPDV APVVAIHEAETADYILDVLVEGVKAKAGDTVEIPLKFENVPSHGIQSFNLSLYYDSKA IEVLKVEPGSIITDPANNFDYNIVYKDSEIVFLFDDDKQKGEGLIKTDGVFAKLTVRI KPDIFKDSGATKKYSLITFGESNFCDFDLKPILAVLKEGKVEIEK" sig_peptide 14044..14130 /locus_tag="ClothDRAFT_1606" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 29" misc_feature <14167..14310 /locus_tag="ClothDRAFT_1606" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature 14395..14820 /locus_tag="ClothDRAFT_1606" /note="Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548" /db_xref="CDD:176100" misc_feature order(14491..14496,14581..14583,14587..14589,14614..14616, 14626..14634,14770..14772,14782..14784,14788..14790) /locus_tag="ClothDRAFT_1606" /note="dockerin binding interface; other site" /db_xref="CDD:176100" gene 14995..15435 /locus_tag="ClothDRAFT_1607" CDS 14995..15435 /locus_tag="ClothDRAFT_1607" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: Krtap16-7; keratin associated protein 16-7" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429746.1" /db_xref="GI:256004771" /translation="MSRVGGLSAKSISQLLSNYIGETVTIFTKSGGQSGAGFTGVILS VNDCFVRLITRIGPPPGCALGNACTGFDVGNKYGKGIAPSGGGCGISGGYAAGYGKGY GPILPANENGAITAGGWNGYPVYTVGSVADIPVDSIVAFVHNAV" gene complement(15501..15905) /locus_tag="ClothDRAFT_1608" CDS complement(15501..15905) /locus_tag="ClothDRAFT_1608" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429747.1" /db_xref="GI:256004772" /translation="MFFLRRRRRKQTEIEKIRQKPDCKTIFDAKSFLFDNTCFSAHMA NYIGETVTVFVESGGISGAGFTGILLFVNEVYIELLISIALPPACSLNNPCILYPVCS YGLGQSYSHFSPLGSLAIIPVDKITSFVHNLV" gene 16232..17770 /locus_tag="ClothDRAFT_1609" CDS 16232..17770 /locus_tag="ClothDRAFT_1609" /inference="protein motif:TFAM:TIGR00368" /note="KEGG: gsu:GSU0489 Mg chelatase-related protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="Mg chelatase, subunit ChlI" /protein_id="ZP_05429748.1" /db_xref="GI:256004773" /db_xref="InterPro:IPR000523" /db_xref="InterPro:IPR001208" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004482" /translation="MLSKIKTMGLMGIDGYVVMVETDISNGIPSFDMVGLGDTAVKES KERVRAAIKNAGFEFPIKRITVNLAPADKKKEGSAFDLPIALGVLTATEQINNKNLDR YAFVGELSLDGEIKPVRGILPMVLSVRDNGVENIVLPIENADEAAVVKDINVLPAKNI RDVVNHLNGALEIKKHEVDIQSIFNGSLDFDVDFADVKGQENVKRALEVAASGGHNCL MIGSPGSGKTMIARRLPTILPLMTFEEALEVTKIHSIAGTLPANTSLITQRPFRAPHH TISNVSLIGGGKIPKPGEMSLAHYGVLFLDELPEFNKDALEVLRQPLEDGVVTISRIN ATLTYPARTTLICAANPCKCGNYLDNTKECTCTPKQIQQYLGKISGPLLDRIDIHIEV ASVKYNDLENEEEGEKSSVIRERVNRTRKIQQERYKGLGIFSNAELTPALIRRFCKLD DKCKEILRNAFEKLGLSARAHNRILKVARTIADMEESESIKANHLLEAIQYRSLDRKK YLNI" misc_feature 16271..17752 /locus_tag="ClothDRAFT_1609" /note="Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606" /db_xref="CDD:30951" misc_feature <16541..16732 /locus_tag="ClothDRAFT_1609" /note="Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362" /db_xref="CDD:114104" misc_feature 16808..17431 /locus_tag="ClothDRAFT_1609" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" gene 17787..18203 /locus_tag="ClothDRAFT_1610" CDS 17787..18203 /locus_tag="ClothDRAFT_1610" /inference="protein motif:PFAM:PF01894" /note="PFAM: protein of unknown function UPF0047; KEGG: dol:Dole_0570 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function UPF0047" /protein_id="ZP_05429749.1" /db_xref="GI:256004774" /db_xref="InterPro:IPR001602" /translation="MKSYRKELVFNIPSRRAYVNITPQVQECIDESGIKEGLVLVNAM HITASVFVNDDEPGLHQDFEKWLETLAPEKPYSQYKHNGYEDNADAHLKRQIMGREVV AAITNGKLDFGPWEQIFYGEFDGKRPKRVLVKIIGE" misc_feature 17787..18197 /locus_tag="ClothDRAFT_1610" /note="Uncharacterized protein family UPF0047; Region: UPF0047; cl00439" /db_xref="CDD:153768" gene 18233..18595 /locus_tag="ClothDRAFT_1611" CDS 18233..18595 /locus_tag="ClothDRAFT_1611" /inference="protein motif:PFAM:PF03733" /note="PFAM: protein of unknown function DUF307; KEGG: sdn:Sden_2147 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF307" /protein_id="ZP_05429750.1" /db_xref="GI:256004775" /db_xref="InterPro:IPR005185" /translation="MRIIGNIIWLLFGGIVLALGWMLAGLILCITIIGIPFGVQCFKI GALVLWPFGREVQIGNFGVGGLLLNIIWIIFFGWELALSHFITGLLFCITIVGIPFGL QHFKLAKLGLVPFGARIN" misc_feature 18233..18589 /locus_tag="ClothDRAFT_1611" /note="hypothetical protein; Provisional; Region: PRK11770" /db_xref="CDD:183306" misc_feature 18242..18397 /locus_tag="ClothDRAFT_1611" /note="Domain of unknown function (DUF307); Region: DUF307; pfam03733" /db_xref="CDD:146394" misc_feature 18428..18586 /locus_tag="ClothDRAFT_1611" /note="Domain of unknown function (DUF307); Region: DUF307; pfam03733" /db_xref="CDD:146394" gene 18802..19557 /locus_tag="ClothDRAFT_1612" CDS 18802..19557 /locus_tag="ClothDRAFT_1612" /EC_number="4.2.99.18" /inference="protein motif:TFAM:TIGR00633" /note="KEGG: hac:Hac_0003 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase" /codon_start=1 /transl_table=11 /product="exodeoxyribonuclease III Xth" /protein_id="ZP_05429751.1" /db_xref="GI:256004776" /db_xref="InterPro:IPR000097" /db_xref="InterPro:IPR004808" /db_xref="InterPro:IPR005135" /translation="MTKLISWNVNGLRACINKGFLDYFKKADADIFCIQESKVQPGQI ELELDGYHQYWNYAERKGYSGTAVFTRIKPLCVQNGIGIDEHDREGRVITLEFDNYYL VNVYTPNAKKELERLDYRMKWEDDFRNYLVGLKAKKPVIVCGDMNVAHKEIDLKNPES NRRSAGFTDEERAKFTELLNAGFIDTFRFFYPDKTGAYTWWSYMFNARARNAGWRIDY FCVSEELKDRLVSASIHDDVMGSDHCPVELQIK" misc_feature 18808..19554 /locus_tag="ClothDRAFT_1612" /note="Endonuclease/Exonuclease/phosphatase family; Region: Exo_endo_phos; cl00490" /db_xref="CDD:186031" gene 19737..20849 /locus_tag="ClothDRAFT_1613" CDS 19737..20849 /locus_tag="ClothDRAFT_1613" /inference="protein motif:TFAM:TIGR00732" /note="TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: gur:Gura_3690 DNA protecting protein DprA" /codon_start=1 /transl_table=11 /product="DNA protecting protein DprA" /protein_id="ZP_05429752.1" /db_xref="GI:256004777" /db_xref="InterPro:IPR003488" /translation="MESNLKEWVWLSSIPGIGAVKSRKLLEHFGDIHNVWSATAAELA VLPFLNRKDILNLTNVKFKQDVERHLENIHKNDIKVITLEDELYPAYLKNIYDPPLVL YMKGTIQEEEKYLAVVGSRRATSYGLDMAKKISRELAECGITVVSGMARGVDSFAHMG ALEVKGRTIAVLGCGLDIVYPYENKKLMENIIESGACLSEYLPGTTPVPGNFPARNRI ISGISLGVVVIEAGERSGSLITANFALEQGREVFALPGNVNSIKSTGTNKLIKEGAKI VTGIDDILEELNIYFIEENTKVSFNKNLQDERILRGLDNDEKKVVECLKLESMHIDNI ARKTGFGIQLVNSILVMLELKGVVEQLPGKIFKLKL" misc_feature 19758..20825 /locus_tag="ClothDRAFT_1613" /note="Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758" /db_xref="CDD:31101" misc_feature 19953..20570 /locus_tag="ClothDRAFT_1613" /note="DNA recombination-mediator protein A; Region: DNA_processg_A; cl00695" /db_xref="CDD:153941" gene 20943..23051 /locus_tag="ClothDRAFT_1614" CDS 20943..23051 /locus_tag="ClothDRAFT_1614" /EC_number="5.99.1.2" /inference="protein motif:TFAM:TIGR01051" /note="KEGG: sat:SYN_02798 DNA topoisomerase I; TIGRFAM: DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein" /codon_start=1 /transl_table=11 /product="DNA topoisomerase I" /protein_id="ZP_05429753.1" /db_xref="GI:256004778" /db_xref="InterPro:IPR000380" /db_xref="InterPro:IPR003601" /db_xref="InterPro:IPR003602" /db_xref="InterPro:IPR005733" /db_xref="InterPro:IPR006154" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR013497" /db_xref="InterPro:IPR013498" /translation="MADKLIIVESPAKAHTIGKFLGKDYKIVASVGHVRDLPKSQMGV DIENDFTPKYITIRGKGEIISKLKKEAKNASTIYLATDPDREGEAISWHLATLLNIDK NEKCRITFNEITKNAVKNAIKSPREINMDLVDAQQARRVLDRIVGYKISPLLWKKVKK GLSAGRVQSVATRLICDREEEIEKFVPEEYWTITAKLLKGGVKAPFEAKFYGLDNKKT ELKSEEEVNKVLDEIKDAVFVVQKVKKGEKKKNPNAPFTTSTMQQEASRKLGFSTKKT MMVAQQLYEGIEVKGVGAVGLVTYIRTDSTRISEEAQNQAAKYIKEKFGESYLPKEKN VYKNKSASQDAHECIRPTSVEMDPESVKDSLTKEQYRLYKLIWDRFVASQMAPAVYDT INADIEAGKYLFKASGSTVKFPGFTVLYQEDKDDETEEGEVIVPELAEGESLKLKKLE PRQHFTQPPPRYTEASLVKALEEKGIGRPSTYAPIITTILARGYVVKEGKTLVPTELG KIVTDIMKNYFQDIVDVEFTAQMEKTLDEVEEGEKRWVDVMRSFYSQFVDVLKNAEEK IGNIEVPEEVTDEICEKCGRNMVIKVGKKGRFLACPGFPECRNAKPILEDAGVTCPKC GGKVYIKKTRKGRKYLGCENNNSDPKCDFMTWDMPSKENCPKCGSFLLKKYSGRKVQL KCSNENCDYVKTGKEKKEDE" misc_feature 20943..22922 /locus_tag="ClothDRAFT_1614" /note="DNA topoisomerase I; Validated; Region: PRK05582" /db_xref="CDD:180146" misc_feature 20952..21317 /locus_tag="ClothDRAFT_1614" /note="TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I. Type IA DNA topoisomerases remove (relax) negative supercoils in...; Region: TOPRIM_TopoIA_TopoI; cd03363" /db_xref="CDD:173783" misc_feature order(20967..20972,20979..20981,21186..21188,21192..21194, 21198..21200) /locus_tag="ClothDRAFT_1614" /note="active site" /db_xref="CDD:173783" misc_feature order(20988..20990,21189..21191,21195..21197,21216..21221, 21225..21230) /locus_tag="ClothDRAFT_1614" /note="interdomain interaction site; other site" /db_xref="CDD:173783" misc_feature order(21186..21188,21192..21194) /locus_tag="ClothDRAFT_1614" /note="putative metal-binding site; other site" /db_xref="CDD:173783" misc_feature 21195..21197 /locus_tag="ClothDRAFT_1614" /note="nucleotide binding site; other site" /db_xref="CDD:173783" misc_feature 21330..22622 /locus_tag="ClothDRAFT_1614" /note="DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded...; Region: TOP1Ac; cd00186" /db_xref="CDD:73184" misc_feature order(21330..21413,21426..21488) /locus_tag="ClothDRAFT_1614" /note="domain I; other site" /db_xref="CDD:73184" misc_feature order(21357..21362,21369..21371,21381..21383,21393..21395, 21783..21785,21795..21797,21846..21848,22380..22385, 22392..22397,22401..22403,22413..22418) /locus_tag="ClothDRAFT_1614" /note="DNA binding groove" /db_xref="CDD:73184" misc_feature order(21459..21461,21471..21473,22488..22490) /locus_tag="ClothDRAFT_1614" /note="phosphate binding site; other site" /db_xref="CDD:73184" misc_feature order(21501..21521,21606..21644,21687..21695,22098..22142, 22146..22202,22281..22313) /locus_tag="ClothDRAFT_1614" /note="domain II; other site" /db_xref="CDD:73184" misc_feature order(21696..21716,21720..21800,21828..21914,21975..22001, 22035..22097) /locus_tag="ClothDRAFT_1614" /note="domain III; other site" /db_xref="CDD:73184" misc_feature order(21729..21731,21741..21749,21978..21980,22053..22055, 22062..22064,22074..22076,22374..22376,22380..22382, 22446..22448) /locus_tag="ClothDRAFT_1614" /note="nucleotide binding site; other site" /db_xref="CDD:73184" misc_feature order(21840..21842,21846..21848,21978..21980) /locus_tag="ClothDRAFT_1614" /note="catalytic site; other site" /db_xref="CDD:73184" misc_feature order(22314..22436,22446..22490,22506..22622) /locus_tag="ClothDRAFT_1614" /note="domain IV; other site" /db_xref="CDD:73184" misc_feature 22674..22781 /locus_tag="ClothDRAFT_1614" /note="Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; cl11977" /db_xref="CDD:143760" misc_feature 22794..22922 /locus_tag="ClothDRAFT_1614" /note="Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; cl11977" /db_xref="CDD:143760" gene 23053..24363 /locus_tag="ClothDRAFT_1615" CDS 23053..24363 /locus_tag="ClothDRAFT_1615" /EC_number="2.1.1.74" /inference="protein motif:TFAM:TIGR00137" /note="KEGG: gbm:Gbem_2710 gid protein; TIGRFAM: gid protein; PFAM: glucose-inhibited division protein A" /codon_start=1 /transl_table=11 /product="gid protein" /protein_id="ZP_05429754.1" /db_xref="GI:256004779" /db_xref="InterPro:IPR002218" /db_xref="InterPro:IPR004417" /db_xref="InterPro:IPR013027" /translation="MIDYINVIGAGLAGCEAAWQIAKRGIKVKLFEMKPKKFSPAHHM ETFAELVCSNSLRSNQLENAVGLLKEEMRLLNSIIMKCADAAQVPAGGALAVDRTKFS QMVTELIKQNENIEVINEEVRELPKEGITIVATGPLTSGDLSKHLADFVGEGYLHFFD AAAPIVTFESIDMNKAFKAARYGRGTDDYINCPMNKEEYEIFWNELVNAELAEVKDFD REVVFEGCMPVETMAKRGKDTLRFGPLKPVGLVDPNTGKEPYAVVQLRQDNSEGTMYN MVGFQTRLKWPEQKRVFRLIPGLENAEFVRYGVMHRNTFINSPVLLDATYCLKKSPNI YFAGQITGVEGYVESASSGMVAGINAAMDFLGKDRVVFPKSTAIGALSHYVSDSSIKN FQPMNVNFGIMESFPLKIRDKRKRNYETAMRALKILKEYVSKYS" misc_feature 23053..24354 /locus_tag="ClothDRAFT_1615" /note="NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; cl11520" /db_xref="CDD:187089" misc_feature 23065..24156 /locus_tag="ClothDRAFT_1615" /note="Glucose inhibited division protein A; Region: GIDA; pfam01134" /db_xref="CDD:144651" gene 24803..25207 /locus_tag="ClothDRAFT_1616" CDS 24803..25207 /locus_tag="ClothDRAFT_1616" /inference="protein motif:TFAM:TIGR01396" /note="TIGRFAM: flagellar basal-body rod protein FlgB; KEGG: gme:Gmet_3115 flagellar basal-body rod protein FlgB" /codon_start=1 /transl_table=11 /product="flagellar basal-body rod protein FlgB" /protein_id="ZP_05429755.1" /db_xref="GI:256004780" /db_xref="InterPro:IPR006300" /translation="MLGRILAGTDVLEKSLDAALLRNEAISQNIANVDTPGYKRKTVA FEEYLNDARAKIKGIRTRPEHIPVGARDVMDIDIKVSEDRSSLSMRLDENNVDIEEEM AQMAKNTIKYYLLTQKISGDFNKIKSVIKEGR" misc_feature 24830..25195 /locus_tag="ClothDRAFT_1616" /note="flagellar basal-body rod protein FlgB; Region: FlgB; TIGR01396" /db_xref="CDD:162337" misc_feature 24842..25186 /locus_tag="ClothDRAFT_1616" /note="flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl09471" /db_xref="CDD:186857" gene 25214..25657 /locus_tag="ClothDRAFT_1617" CDS 25214..25657 /locus_tag="ClothDRAFT_1617" /inference="protein motif:TFAM:TIGR01395" /note="TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: dvl:Dvul_2666 flagellar basal-body rod protein FlgC" /codon_start=1 /transl_table=11 /product="flagellar basal-body rod protein FlgC" /protein_id="ZP_05429756.1" /db_xref="GI:256004781" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR006299" /db_xref="InterPro:IPR010930" /translation="MGYFTSLDISASALTAQRLRMDTISQNIANANTTRTENGQPYRR KTVLFEEKSSTGSFSEYLENSIRGKTAGAGVRVTGIVEDRSPFKRVYDPGHPDADEEG YVLMPNVDVITEMVNMISATRAYEANITAINTTKGLAMKALEIGR" misc_feature 25214..25654 /locus_tag="ClothDRAFT_1617" /note="flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681" /db_xref="CDD:180197" misc_feature 25232..25318 /locus_tag="ClothDRAFT_1617" /note="Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460" /db_xref="CDD:109515" misc_feature 25532..25648 /locus_tag="ClothDRAFT_1617" /note="Domain of unknown function (DUF1078); Region: DUF1078; pfam06429" /db_xref="CDD:148188" gene 25716..26030 /locus_tag="ClothDRAFT_1618" CDS 25716..26030 /locus_tag="ClothDRAFT_1618" /inference="protein motif:TFAM:TIGR00205" /note="TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: bba:Bd3405 hypothetical protein" /codon_start=1 /transl_table=11 /product="flagellar hook-basal body complex subunit FliE" /protein_id="ZP_05429757.1" /db_xref="GI:256004782" /db_xref="InterPro:IPR001624" /translation="MAVNGINLVTPSVSGIDFTVGNTISNKNENVVQSFSDYLKNAIK QVDELEKQSKAVAEDFAAGKTDNIHEVMIAAQKADIAIQFTLQIRNKILDAYNEIMRM QI" misc_feature 25743..26027 /locus_tag="ClothDRAFT_1618" /note="Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139" /db_xref="CDD:186838" gene 26116..27669 /locus_tag="ClothDRAFT_1619" CDS 26116..27669 /locus_tag="ClothDRAFT_1619" /inference="protein motif:TFAM:TIGR00206" /note="TIGRFAM: flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring domain protein; KEGG: gsu:GSU0410 flagellar M-ring protein FliF" /codon_start=1 /transl_table=11 /product="flagellar M-ring protein FliF" /protein_id="ZP_05429758.1" /db_xref="GI:256004783" /db_xref="InterPro:IPR000067" /db_xref="InterPro:IPR006182" /db_xref="InterPro:IPR013556" /translation="MPEVLSKMQQQVTDFWKNLDKSQKTRILVTSGILVVVLTIAIVM LTRTTYVPLITVEDPDSISAIEEALKERNIKYKHGEGRRILVDSKDKNEAEFALASAG LTEPGMTFEDAWSLLKVSSSESDKKQLWQNFKKNSLIAKLKMFDNVKDADIELTIPED TMFFTDSKSEAKAAVRITPKGELTPEQVEGIVMVVASSIEGLDPKNVTVVDNNFNILN QDLSDGMNIPSSHYKLKLRIKEELEKNIKNLYSGRSDSYDFISVAVNPVLDLDKVTKN RKEIEKPTGLDEAVVSEERKTEELINGNQGGAPGMDANPGTGDVPTYPIDAGQNSSYE SKSEIINRIFTETLTAEEKAIGTMNFQESSMTVALWYGNRVPDDSKLTDEFIEEFKQG LSNATGIPVGKITVNKQKLAPQEEEIVPMSERIKQFIDDYGFFALLIILIIALMLSVM PRKKKSPQLAPELATAGGPNVDEAEEELPPINFEEHSEIKKQIENFVKQKPESVAQLL RNWLSEDWD" misc_feature 26116..27660 /locus_tag="ClothDRAFT_1619" /note="flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007" /db_xref="CDD:180348" misc_feature 26209..26778 /locus_tag="ClothDRAFT_1619" /note="Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907" /db_xref="CDD:186494" misc_feature 26899..27312 /locus_tag="ClothDRAFT_1619" /note="Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345" /db_xref="CDD:149415" gene 27721..28743 /locus_tag="ClothDRAFT_1620" CDS 27721..28743 /locus_tag="ClothDRAFT_1620" /inference="protein motif:TFAM:TIGR00207" /note="TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; KEGG: gur:Gura_4212 flagellar motor switch protein FliG" /codon_start=1 /transl_table=11 /product="flagellar motor switch protein FliG" /protein_id="ZP_05429759.1" /db_xref="GI:256004784" /db_xref="InterPro:IPR000090" /translation="MARGGSTKSELSGKEKAAMLLIALGPERSAEIFKHLKEDEIEQL TLEIANIRTVSPEDKERVLEEFYQICLAQNYIAEGGINYAKEILEKALGTQKALDVLN KLTVSLQVRPFDFVRKADPSQLINFIQNEHPQTIALILSYLKPQQASIVLSALPQDKQ ADVARRIATMDRTSPEVIKEVERVLEKKLSAIVTEDFTAAGGVQAIVDILNNVDRGTE KYIMETLEVEDTDLAEEIKKRMFVFEDILTLDNRSIQRFLREVDNNQLAIALKGTNDE VKNKIFANMSKRMAEMVKEDMEFMGPVRLKDVEEAQQKIVNVIRKLEDAGEIVISRGG GDDIVV" misc_feature 27721..28740 /locus_tag="ClothDRAFT_1620" /note="flagellar motor switch protein G; Validated; Region: fliG; PRK05686" /db_xref="CDD:180201" misc_feature 28384..28710 /locus_tag="ClothDRAFT_1620" /note="FliG C-terminal domain; Region: FliG_C; pfam01706" /db_xref="CDD:145059" gene 28736..29527 /locus_tag="ClothDRAFT_1621" CDS 28736..29527 /locus_tag="ClothDRAFT_1621" /inference="protein motif:PFAM:PF02108" /note="PFAM: flagellar assembly protein FliH; KEGG: sat:SYN_01472 flagellar assembly protein" /codon_start=1 /transl_table=11 /product="flagellar assembly protein FliH" /protein_id="ZP_05429760.1" /db_xref="GI:256004785" /db_xref="InterPro:IPR000563" /translation="MYSNKVFKSSQINIGIPVQIKVPITPANYQNVKKVKEPEIDFDS CINEKSELLSKKVENEKDVLEKARKQADEIIRQAELEAAKILEEAKEKGLLLMAEIEE DSRQKGFEKGYEEAKSQYEDLIQEAELIRENALKEYQETLQSIEKDALNIILDISRKV IGTEISMNKEKLLEMIAQAFERCSNRENITLKVSSADYDFIIENKDRILSMVEGIGQL EIVKDQALKLGALILETPYGSVDAGMDTKLKKIEEAFFKVLASRK" misc_feature 28916..29464 /locus_tag="ClothDRAFT_1621" /note="type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499" /db_xref="CDD:162889" misc_feature 29075..29488 /locus_tag="ClothDRAFT_1621" /note="Flagellar assembly protein FliH; Region: FliH; pfam02108" /db_xref="CDD:111047" gene 29572..30885 /locus_tag="ClothDRAFT_1622" CDS 29572..30885 /locus_tag="ClothDRAFT_1622" /EC_number="3.6.3.14" /inference="protein motif:TFAM:TIGR01026" /note="KEGG: gur:Gura_4210 flagellar protein export ATPase FliI; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="ATPase, FliI/YscN family" /protein_id="ZP_05429761.1" /db_xref="GI:256004786" /db_xref="InterPro:IPR000194" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004100" /db_xref="InterPro:IPR005714" /translation="MATIDFSKYYDVLDNRDFIEYTGKVSKVVGLTIESNGPEVNIGE ICKINALRENKVISAEAVGFRDNKVLLMPLGDMNGIGPGSKVVATRDYLSVGVGNALI GRVIDGMGRPIDGKGEIVTETTYPVENKPPHPLKRNRIKEPLPLGVKTIDGLLTVGKG QRVGIFAGSGVGKSTLIGMIARNTKADVNVIALIGERGREVREFIEKDLKEEGLKRSV VVVATSDQPALIRLKGALMATAIAEYFRDQGKDVLLLMDSLTRFAMAQREIGLSIGEP PVSRGYTPSVFSIMPKLLERAGNSQSGSITGLYTVLVDGDDLTEPVTDTARGILDGHI VLSRNLANKNQYPAIDVLASVSRVMPDIVDDEHQKIANDIKKTMAIYREAEDLINVGA YAKGSNEKIDYAIEVIDKIQEFIKQGVHERYSYEETINLMKNVLI" misc_feature 29638..30879 /locus_tag="ClothDRAFT_1622" /note="flagellar protein export ATPase FliI; Region: FliI_clade2; TIGR03497" /db_xref="CDD:132536" misc_feature 29644..29838 /locus_tag="ClothDRAFT_1622" /note="ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874" /db_xref="CDD:145823" misc_feature 29848..30822 /locus_tag="ClothDRAFT_1622" /note="Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136" /db_xref="CDD:30002" misc_feature 30073..30093 /locus_tag="ClothDRAFT_1622" /note="Walker A motif/ATP binding site; other site" /db_xref="CDD:30002" misc_feature 30328..30342 /locus_tag="ClothDRAFT_1622" /note="Walker B motif; other site" /db_xref="CDD:30002" gene 30907..31365 /locus_tag="ClothDRAFT_1623" CDS 30907..31365 /locus_tag="ClothDRAFT_1623" /inference="protein motif:TFAM:TIGR02473" /note="TIGRFAM: flagellar export protein FliJ; PFAM: flagellar FliJ protein; KEGG: glo:Glov_3300 flagellar export protein FliJ" /codon_start=1 /transl_table=11 /product="flagellar export protein FliJ" /protein_id="ZP_05429762.1" /db_xref="GI:256004787" /db_xref="InterPro:IPR000809" /db_xref="InterPro:IPR012823" /translation="MIIVGKFVFRMQSLLNLKIQMENSLKNELGKAVRELERQKDILN RLNREMNECIENINGKFGEGISVGELRKYNTYISYLSDRVKLQKENIKKAQLVVDKYR DKLIKAMQERKVLEKLREKKYEEYVREQLKEEQKLNDEIVSFNISNSEEE" misc_feature 30922..31338 /locus_tag="ClothDRAFT_1623" /note="Flagellar FliJ protein; Region: FliJ; cl09161" /db_xref="CDD:186845" misc_feature 30928..31335 /locus_tag="ClothDRAFT_1623" /note="flagellar export protein FliJ; Region: flagell_FliJ; TIGR02473" /db_xref="CDD:131526" gene 31427..32257 /locus_tag="ClothDRAFT_1624" CDS 31427..32257 /locus_tag="ClothDRAFT_1624" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429763.1" /db_xref="GI:256004788" /translation="MAKEKIKETVKNPEAQGSGTEKKKAEKNGFLFGLLVLLITLIVI VSVVGGVFFIVIKNNVNGLAEKYRNNLKNIPVLRMALPPPPADYDPLDPKNLKLDELI EKYNQFRKENGELAKKLEETEKALNELQSSQADIEALRKENDQIKAEMEAQKTRYKEE LKKAEELLVQADKEGFKEFYEKMNEKLAQSLYEEILKEEKANEKAKEFAQIYEKMDTK AAAKIFEELGDSQLDLVVETLRNMKKDVAAEIISEMSQSYAAKVTEKLSKVYGIEFEK " misc_feature 32054..>32227 /locus_tag="ClothDRAFT_1624" /note="MgtE intracellular N domain; Region: MgtE_N; pfam03448" /db_xref="CDD:146204" gene 32302..33888 /locus_tag="ClothDRAFT_1625" CDS 32302..33888 /locus_tag="ClothDRAFT_1625" /inference="protein motif:PFAM:PF02120" /note="PFAM: flagellar hook-length control protein; KEGG: viral A-type inclusion protein" /codon_start=1 /transl_table=11 /product="flagellar hook-length control protein" /protein_id="ZP_05429764.1" /db_xref="GI:256004789" /db_xref="InterPro:IPR001635" /translation="MITQHLIPDFIAKMTGSTEVQKSAGMKKSSSSQFKDTLDLAVEK SYAWQSGTKSYEYAMDIKDRPYQRLQNKNILDSAETKERRPDRTKPFNKASNQITSRA SDKAERTASPEEENIEGENDRKLKGKAMEKALAEVLGISVEELEKLMAQLGINFENAD GETGIQEAADKISAYLGLNQDEKMALAEMMSLVQKQVEQAFKDVQSAYDATRYDMKDE NEAYGVELFHAETETAVEDTSALRNDLDVSKVSQEVKNKLDEETDGFLKQIAAKVVEV VQKDESTAGLKTVSVNGENIEEIGLKTDVEDIGNVREAKYSSDEKDSADNSGNAGSET SSMASRGVEAESAAKNSNNIQFEAVSNLTVQRATGQAEPDKTRNIIPVTNKEIVEQVV EKAKVVLSGDKSEMVIDLKPEHLGKLELKIVTERGMVVAKFVAENEQVKAALESNMNM LKESLEKQGFLVEGFSVTVGDNKRRENSRDKTNQGTANQRISGEKLQVSDMTGVERMQ RIHENIDPYSYGSSSIDLTA" misc_feature <33262..33792 /locus_tag="ClothDRAFT_1625" /note="Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144" /db_xref="CDD:32958" misc_feature 33478..33729 /locus_tag="ClothDRAFT_1625" /note="Flagellar hook-length control protein FliK; Region: Flg_hook; cl14669" /db_xref="CDD:187423" gene 33904..34875 /locus_tag="ClothDRAFT_1626" CDS 33904..34875 /locus_tag="ClothDRAFT_1626" /inference="protein motif:PFAM:PF03963" /note="PFAM: flagellar hook capping protein; KEGG: dvm:DvMF_0247 flagellar hook capping protein" /codon_start=1 /transl_table=11 /product="flagellar hook capping protein" /protein_id="ZP_05429765.1" /db_xref="GI:256004790" /db_xref="InterPro:IPR005648" /translation="MAVDAVGRQKTIQEIIDNTTNKSTQRNTGELGKDEFLNLLITQL QYQDPLNPVDDKEFISQMAQFSALEQMQNLNKSFSATKAFGMIGKYITGTTSNGSDSG AGFVEGIVRSVKMENGKILLEVNGLDVPVDNVLSVSEESNYYYKYNSSNISQYTGIIG YEVSGSVYDPSTGDIVGVSGIVREIQKGIYEDYAVMDGVEVIISGIDTEFNSADPNFR KDYLTENVGQRVSLIITDAYGYGFKVPVTGVLKDFKIAPNGKIIGILDGVYVPVDSIS NIKKPSANTGAADGTNENPQVEQSQTEESQVEEPQVGEPRDEESDSV" misc_feature 33955..34314 /locus_tag="ClothDRAFT_1626" /note="Flagellar hook capping protein; Region: FlgD; cl04347" /db_xref="CDD:186627" gene 34925..35314 /locus_tag="ClothDRAFT_1627" CDS 34925..35314 /locus_tag="ClothDRAFT_1627" /inference="protein motif:TFAM:TIGR02530" /note="TIGRFAM: flagellar operon protein; KEGG: geo:Geob_0502 flagellar operon protein" /codon_start=1 /transl_table=11 /product="flagellar operon protein" /protein_id="ZP_05429766.1" /db_xref="GI:256004791" /db_xref="InterPro:IPR013367" /translation="MIVNNNYYVNISRINGSQRAIPSGKPDGKVQGSFEEILESKVNE NRGLKFSKHAEMRLQLRNIKLTDEQKEKISKAVQKAEEKGVKDSLVLIDDIAFVVNVR NRTVITAVNSNELKENVFTNIDGAVFA" misc_feature 35021..35305 /locus_tag="ClothDRAFT_1627" /note="Protein of unknown function (DUF3766); Region: DUF3766; cl11797" /db_xref="CDD:164263" gene 35480..36802 /locus_tag="ClothDRAFT_1628" CDS 35480..36802 /locus_tag="ClothDRAFT_1628" /inference="protein motif:PFAM:PF06429" /note="PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; flagellar basal body rod protein; KEGG: pca:Pcar_1183 flagellar biosynthesis, hook protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1078 domain protein" /protein_id="ZP_05429767.1" /db_xref="GI:256004792" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR010930" /db_xref="InterPro:IPR011491" /translation="MMRSMFSGVSGLQAHQTKMDVIGNNVANVNTVGFKSSRVTFQEV FSQTLKGASSPDPTTGRGGTNPMQVGLGLGVATIDTLMTRGSVQRTDNPTDLAIEGDG FFIVKGGSSDTFKFTRAGNFGIDRLGNLVTGSGLNVYGWQSYTKLPDGTYKFDTESQI EPINLYSDDVNKNKRMIAAKATTYAIFEGNLDASYSIYSSAASGTSSNNRFTMPVTVY DSLGNSYKINISFWKTDVTGGVTTWTWQVDSGNGVTASGATGTILFDDQGQVIESSAV TPSITIIPDSSVGSQNINVKLDFSRLTMYAADSSAKATNVDGYPAGSLVTFSIGSDGM IMGIYSNGQQQPLGLIALASFDNPAGLEKVGENMYIPTSNSGEFKKGVKAGTEGVGTL SPGTLEMSNVDLSKEFTEMIITQRGFQANSRIITTSDEMLQELVNLKR" misc_feature 35486..36796 /locus_tag="ClothDRAFT_1628" /note="flagellar hook protein FlgE; Validated; Region: flgE; PRK05682" /db_xref="CDD:180198" misc_feature 35492..35584 /locus_tag="ClothDRAFT_1628" /note="Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460" /db_xref="CDD:109515" misc_feature 36110..36436 /locus_tag="ClothDRAFT_1628" /note="Flagellar basal body protein FlaE; Region: FlaE; pfam07559" /db_xref="CDD:148912" misc_feature 36458..36736 /locus_tag="ClothDRAFT_1628" /note="flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490" /db_xref="CDD:162884" gene 37016..37228 /locus_tag="ClothDRAFT_1629" CDS 37016..37228 /locus_tag="ClothDRAFT_1629" /inference="protein motif:PFAM:PF06289" /note="PFAM: flagellar FlbD family protein; KEGG: gme:Gmet_0462 flagellar protein" /codon_start=1 /transl_table=11 /product="flagellar FlbD family protein" /protein_id="ZP_05429768.1" /db_xref="GI:256004793" /db_xref="InterPro:IPR009384" /translation="MIKLTKLNGKPFILNSDLIEFIEQTPDTIISTTTGKKVVVVESV EEVVEKVLQYKRKIYLFKDVFINQDR" misc_feature 37016..37195 /locus_tag="ClothDRAFT_1629" /note="Flagellar protein (FlbD); Region: FlbD; cl00683" /db_xref="CDD:153933" gene 37310..37813 /locus_tag="ClothDRAFT_1630" CDS 37310..37813 /locus_tag="ClothDRAFT_1630" /inference="protein motif:PFAM:PF03748" /note="PFAM: flagellar basal body-associated protein FliL" /codon_start=1 /transl_table=11 /product="flagellar basal body-associated protein FliL" /protein_id="ZP_05429769.1" /db_xref="GI:256004794" /db_xref="InterPro:IPR005503" /translation="MERKSSFFVLIGVVAFLSLALALLAGYIFFVQGGRAEGPNSSVK VVVTPKDKDLLKMKLFDEKTPFNLKSADSKKISVIVVNVELSYFAKVKGISDTTAKIE SNKSKLQEIVGTYFQSLTLEEVMKSDAKEKARADLTKMMNEQLLANENINSDIIYTVV FDQWFYQ" sig_peptide 37310..37420 /locus_tag="ClothDRAFT_1630" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.466 at residue 37" misc_feature <37505..37756 /locus_tag="ClothDRAFT_1630" /note="Flagellar basal body-associated protein FliL; Region: FliL; cl00681" /db_xref="CDD:186142" gene 37826..38812 /locus_tag="ClothDRAFT_1631" CDS 37826..38812 /locus_tag="ClothDRAFT_1631" /inference="protein motif:TFAM:TIGR01397" /note="TIGRFAM: flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; KEGG: tdn:Suden_0707 flagellar motor switch protein FliM" /codon_start=1 /transl_table=11 /product="flagellar motor switch protein FliM" /protein_id="ZP_05429770.1" /db_xref="GI:256004795" /db_xref="InterPro:IPR001543" /db_xref="InterPro:IPR001689" /translation="MGDILSQNEIDDLLKALNTGELDVQQISSKIEERKIKTHDFRRP SKFAKDHVRTLNVIHDNYARIITNFLSGYLRTLVQVEVISVEPIAYYEFNNSISNPAV LAVIDFAPLTGSIILEMAPPVAYALIDRILGGKGLPIERVREFTEVEIAIIERIIIQL VNLMREPWENVVELKPRLEKIETNAQFAQIVSANETVALITLGAKIGEVEGMINLCIP HIVVEPIVSKLNTKFWFSSVEKEATKEDKETIQKKIEYTKVPVRAILGRATIQVADFL ELQPGDVITLDSNVNGNLDVLVGDLLKFRGSPGVKKNRNAIKITEVIRREDE" misc_feature 37826..38809 /locus_tag="ClothDRAFT_1631" /note="flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666" /db_xref="CDD:180651" misc_feature 38573..38803 /locus_tag="ClothDRAFT_1631" /note="Surface presentation of antigens (SPOA); Region: SpoA; cl00819" /db_xref="CDD:186206" gene 38814..40034 /locus_tag="ClothDRAFT_1632" CDS 38814..40034 /locus_tag="ClothDRAFT_1632" /inference="protein motif:TFAM:TIGR02480" /note="TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: ppd:Ppro_3438 flagellar motor switch protein FliN" /codon_start=1 /transl_table=11 /product="CheC, inhibitor of MCP methylation / FliN fusion protein" /protein_id="ZP_05429771.1" /db_xref="GI:256004796" /db_xref="InterPro:IPR001172" /db_xref="InterPro:IPR001543" /db_xref="InterPro:IPR007597" /db_xref="InterPro:IPR012826" /translation="MEDMLSQAEIDALLNGSSSEGNEENSANEELTSQEIDALGEIGN ISMGTSATTLNSLLGQRVVITTPKVSVCTWEELAKEYHSSYVAVKVEYTEGLDGMNLL LLKEDDAKVITDLMMGGDGSNKEGELTDLHLSAISEAMNQMIGSAATSMSSMFNKRID ISPPKAFPMTLDAAVPEAEFPRGDKIVKVAFKMVIGELIDSQIMQLLPIDFAKKMVSN IMNSKPEDNQVIEEVAASAVQEPVAGQHNEQYYHAQPSQQPYQQPPQQPYQQPYQQPY HQPYQQQYQQYYQPYEQPPRQNDGYRNPINVQPAQFEAFDDGSKISIDKKNIGLIMDV PLQVTVELGRTNKLIKDILEFGPGSIIELDKLAGEPVDILVNGKVIAIGEVVVIDESF GVRITDILHPSKRL" misc_feature 38814..40031 /locus_tag="ClothDRAFT_1632" /note="flagellar motor switch protein; Validated; Region: PRK08119" /db_xref="CDD:181236" misc_feature 38916..39026 /locus_tag="ClothDRAFT_1632" /note="CheC-like family; Region: CheC; pfam04509" /db_xref="CDD:113285" misc_feature 39204..39308 /locus_tag="ClothDRAFT_1632" /note="CheC-like family; Region: CheC; pfam04509" /db_xref="CDD:113285" misc_feature 39792..40022 /locus_tag="ClothDRAFT_1632" /note="Surface presentation of antigens (SPOA); Region: SpoA; cl00819" /db_xref="CDD:186206" gene 40154..40516 /locus_tag="ClothDRAFT_1633" CDS 40154..40516 /locus_tag="ClothDRAFT_1633" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_6693 fibril biogenesis regulator DifD" /codon_start=1 /transl_table=11 /product="response regulator receiver protein" /protein_id="ZP_05429772.1" /db_xref="GI:256004797" /db_xref="InterPro:IPR001789" /translation="MGKRILIVDDAAFMRMMIKDILTKNGYEVAGEAENGARAIDKYK ELNPDLVIMDITMPEVDGIAAVREIKKINADSKIIMCSAMGQQAMVIESIQAGARDFI VKPFQAERVVEAVKKVLG" misc_feature 40169..40510 /locus_tag="ClothDRAFT_1633" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(40178..40183,40313..40315,40337..40339,40397..40399, 40454..40456,40463..40468) /locus_tag="ClothDRAFT_1633" /note="active site" /db_xref="CDD:29071" misc_feature 40313..40315 /locus_tag="ClothDRAFT_1633" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature order(40322..40327,40331..40339) /locus_tag="ClothDRAFT_1633" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature 40463..40471 /locus_tag="ClothDRAFT_1633" /note="dimerization interface; other site" /db_xref="CDD:29071" gene 40586..41083 /locus_tag="ClothDRAFT_1634" CDS 40586..41083 /locus_tag="ClothDRAFT_1634" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429773.1" /db_xref="GI:256004798" /translation="METFISAVMFTVVFGSVLFLAYVTTKFIGTRTNKIVKGKYIKII ETVNLGFDSRLHLVKAGEEFVLISTCGKNVQMLAKVKLEGYYSDEAEETENDFKFREI FSKYAQGFSKKMEGMSFFKAESGEKEQTGSVPVFNTNLNRLKKITASIASYKTEDGEE YTNEN" misc_feature 40619..40822 /locus_tag="ClothDRAFT_1634" /note="Flagellar biosynthesis protein, FliO; Region: FliO; cl01247" /db_xref="CDD:186399" gene 41073..41855 /locus_tag="ClothDRAFT_1635" CDS 41073..41855 /locus_tag="ClothDRAFT_1635" /inference="protein motif:TFAM:TIGR01103" /note="TIGRFAM: flagellar biosynthetic protein FliP; PFAM: type III secretion system inner membrane P protein; KEGG: gme:Gmet_3097 flagellar biosynthesis protein FliP" /codon_start=1 /transl_table=11 /product="flagellar biosynthetic protein FliP" /protein_id="ZP_05429774.1" /db_xref="GI:256004799" /db_xref="InterPro:IPR005837" /db_xref="InterPro:IPR005838" /translation="MKTRLKYLGIILLTITVFMLITSNVYAEPDSIALPKLGFTVEPS DNPQDVSTTIQIIVLLTILSLAPSILIMMTSFVRIIIVLSFFRNAIGTQQMPPNQVLI GLALFLTLFIMRPVLTEINETAFKPYTNQEITQEVALERSSDIIKRFMLKQTSKNDLG LFVSLSGMETPIKEEDIPKLPLTIVIPAFIISELTIAFKIGFLIYIPFLVIDMVVSST LMSMGMMMLPPVMISLPFKILLFIMVGGWNLMTQMIVNSFVT" sig_peptide 41073..41156 /locus_tag="ClothDRAFT_1635" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 28" misc_feature 41115..41852 /locus_tag="ClothDRAFT_1635" /note="FliP family; Region: FliP; cl00593" /db_xref="CDD:186095" gene 41908..42177 /locus_tag="ClothDRAFT_1636" CDS 41908..42177 /locus_tag="ClothDRAFT_1636" /inference="protein motif:TFAM:TIGR01402" /note="TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; KEGG: dat:HRM2_37150 FliQ" /codon_start=1 /transl_table=11 /product="flagellar biosynthetic protein FliQ" /protein_id="ZP_05429775.1" /db_xref="GI:256004800" /db_xref="InterPro:IPR002191" /db_xref="InterPro:IPR006305" /translation="MEQGLVMELAQKAIMTVLYVAAPMLGLSLLVGLAVSIFQATTQI QEQTLTFIPKILSVLGAIAIFGPWMLRVLIEFTQAIYMNINHYIR" misc_feature 41908..42174 /locus_tag="ClothDRAFT_1636" /note="Bacterial export proteins, family 3; Region: Bac_export_3; cl00867" /db_xref="CDD:186229" gene 42207..42992 /locus_tag="ClothDRAFT_1637" CDS 42207..42992 /locus_tag="ClothDRAFT_1637" /inference="protein motif:TFAM:TIGR01400" /note="TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: gur:Gura_4197 flagellar biosynthetic protein FliR" /codon_start=1 /transl_table=11 /product="flagellar biosynthetic protein FliR" /protein_id="ZP_05429776.1" /db_xref="GI:256004801" /db_xref="InterPro:IPR002010" /db_xref="InterPro:IPR006303" /translation="MFVLEGILHVDIEVFMLIFVRMTGLFVIAPIFGSRNIPTYCKIG FSFMTALILVNTIKVQELYFSNIYEYFILVLKEFLVGITLGYVAYMIFTAIYVAGQFI DMQIGFGVVNVIDPLNSTQVSITSNFYFLLCMLVFLICRGHYILIRALFASYNYIPVG TGVFGEDMVNDIVRVFGNIFLIAFKISAPITISIMISEVALGIVSKTVPQLNVFMVGM PLKIILGLAVMVITIPMFLNLVENLITGIDNEMHIFLKDMAPK" misc_feature 42240..42947 /locus_tag="ClothDRAFT_1637" /note="Bacterial export proteins, family 1; Region: Bac_export_1; cl00734" /db_xref="CDD:186167" gene 42989..44167 /locus_tag="ClothDRAFT_1638" CDS 42989..44167 /locus_tag="ClothDRAFT_1638" /inference="protein motif:TFAM:TIGR00328" /note="TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; KEGG: sat:SYN_02832 flagellar biosynthesis pathway component" /codon_start=1 /transl_table=11 /product="flagellar biosynthetic protein FlhB" /protein_id="ZP_05429777.1" /db_xref="GI:256004802" /db_xref="InterPro:IPR006135" /db_xref="InterPro:IPR006136" /translation="MKLKYFLKEVLSKFGKNKEFKIHQTSTGRIKANLQLFADNGEKT EKATPRKRSKAREEGQVLQSRELNSAIVLLSAFVTLRIFGQYMYEEILKCLKVAITVY PLNDGLFTIDGLFELYGETVITFLKIATPVLMVVLIAGIGSAYAQVGFLFTTKTLGIK LSRINPLKGFKRIFSLKSLVELLKSIIKIALVGYIGYGYIKGEMTNVLGMMDVDVVSS ASFLGSTILNAAIRMCIAFVVIGVADYGYQWWEYEKSLRMSKQEIKEENKEVEGNPEI KSRIRQKQRQMSMRRMLQDIPKADVVITNPTHYAVAIKYDPKEADAPVVVAKGQDYMA LRIKEIAKEHKVEIVENKPLAQTLYKTVEIGGKIPPELYQAVAEVLAFVYSLKEKMKK " misc_feature 43100..44164 /locus_tag="ClothDRAFT_1638" /note="Flagellar biosynthesis pathway, component FlhB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhB; cl12017" /db_xref="CDD:187162" misc_feature 43103..44140 /locus_tag="ClothDRAFT_1638" /note="FlhB HrpN YscU SpaS Family; Region: Bac_export_2; pfam01312" /db_xref="CDD:110325" gene 44208..46238 /locus_tag="ClothDRAFT_1639" CDS 44208..46238 /locus_tag="ClothDRAFT_1639" /inference="protein motif:TFAM:TIGR01398" /note="TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: dal:Dalk_1003 flagellar biosynthesis protein FlhA" /codon_start=1 /transl_table=11 /product="flagellar biosynthesis protein FlhA" /protein_id="ZP_05429778.1" /db_xref="GI:256004803" /db_xref="InterPro:IPR001712" /db_xref="InterPro:IPR006301" /translation="MKAKIGDISVAVMFVAIVLIIILPVPSGVLDILLALNISLAVVI LLNVVYSKEPLQLSVFPSLLLFTTLYRLALNIKSTTLILAQGEAGEVIRGFGNFVAQG NLVVGAIIFLIITIVQFLVITKGTERVSEVAARFTLDAMPGKQMAIDADLNAGLITEA EAKERRKKIQRESDFYGAMDGATKFVKGDAIAGLIITIINVVGGIIIGVIMRNEEIGE ALQNYAILTIGDGLVSQVPALLISVATGLIVTKSTSDEGISNDLRRQIVYNPKVFFIA AGFCILLSIPLATLPFLALAALFIIVGLQLKKQSVEVEKQEEIQIEKNEVEEIRKPEN VVNLLQVDPIELEFGYGIIPLADVNQGGDLLDRVVMIRRQLALELGMIVPIIRLRDNI QLNPNEYVIKIKGVEVAGGELMLDHYLAMSPGFVEEEIEGIKTTEPAFGLPAVWITEA QRDKAEMLGYTVVDPPSIIATHLTEVIKAHAHELTGRQEVQTIIDKVKENYPAIVEEL VPKVMTIGEIQKVIANLLKEGVSVRDIVTILETLADYAPITHDTDMLTEYVRQALGRA ISKKFIRDKKSTVITLDPKLEQMIMDSVQKTEHGSYINLEPSVINKILNNLSKQVQKL VQLGQQPIVLASPFVRLYFRRLSEQSIPGLVVLSYNELDPSIEIQSIGTVSI" misc_feature 44214..46235 /locus_tag="ClothDRAFT_1639" /note="flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012" /db_xref="CDD:180350" misc_feature 44292..46211 /locus_tag="ClothDRAFT_1639" /note="FHIPEP family; Region: FHIPEP; cl07980" /db_xref="CDD:186726" gene 46240..47451 /locus_tag="ClothDRAFT_1640" CDS 46240..47451 /locus_tag="ClothDRAFT_1640" /inference="protein motif:PFAM:PF00448" /note="PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: AAA ATPase; KEGG: geo:Geob_0624 GTP-binding signal recognition particle SRP54 G-domain protein" /codon_start=1 /transl_table=11 /product="GTP-binding signal recognition particle SRP54 G- domain" /protein_id="ZP_05429779.1" /db_xref="GI:256004804" /db_xref="InterPro:IPR000897" /db_xref="InterPro:IPR003593" /translation="MKIRRYIGKDTQEALLKVKMDLGSDAIILNTRKIRQKGFFKMFS KPLVEVLASVDDNYGTNSRRTAYESRGKNDRGYDVVSGGNLSYNENLRSKFDEKEEKI HLLENKIIGMEEKINKIYEQIQKPSEKLIAATNDDNEQPQSKVLDLFYNNLLKNEVDT EIVKQLISVVRGKVKENVSVSETASILYNLISEMMGKPSDIKLRNDGKPTVVMLVGPT GVGKTTTLAKIAANYSLNLNKNVGLITADTYRIAAVEQLKTYADILGMPLKVIYSANE IQDAIKEYSDKDLILIDTAGRSYKNKEHFDELKTLVEVTNADEIYLVLSTTTGMRNCR EIIEHYSFLENYKLIFTKLDESSALGLILNSRRLTNRDLSFVTTGQSVPDDIELANVD MITKNLLGSIS" misc_feature 46240..47439 /locus_tag="ClothDRAFT_1640" /note="flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703" /db_xref="CDD:180213" misc_feature 46867..47367 /locus_tag="ClothDRAFT_1640" /note="Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras...; Region: Ras_like_GTPase; cl10444" /db_xref="CDD:186996" gene 47452..48360 /locus_tag="ClothDRAFT_1641" CDS 47452..48360 /locus_tag="ClothDRAFT_1641" /inference="protein motif:PFAM:PF01656" /note="PFAM: Cobyrinic acid ac-diamide synthase; KEGG: ppd:Ppro_3446 cobyrinic acid a,c-diamide synthase" /codon_start=1 /transl_table=11 /product="Cobyrinic acid ac-diamide synthase" /protein_id="ZP_05429780.1" /db_xref="GI:256004805" /db_xref="InterPro:IPR002586" /translation="MIDQAEKLRQIIDDLKFRNAVTLDNPSGVREKTAKVITVTSGKG GVGKTNITINLAIALSELGKRVTILDADFGLANIDILLGIVPKYTLVDVLYDKKNILE VLTDGPKNIKFMSGGSGVEELVKLDSTQLEKFVSNISLLDKLSDVILIDTGAGLSESV MSFVMAADEVFLVTTPEPTSITDAYALIKMISNRENNKIIRVVVNRAENANEAKDILN RLSMVTEKFLAMKLYPLGFIPQDESVIKAVKMQQPFSLSFPKCDATKHIKEISKRLIE GSTGLSNRQEGGIKGFVRRLVNLMNA" misc_feature 47599..48342 /locus_tag="ClothDRAFT_1641" /note="Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455" /db_xref="CDD:30803" misc_feature 47599..>47691 /locus_tag="ClothDRAFT_1641" /note="Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras...; Region: Ras_like_GTPase; cl10444" /db_xref="CDD:186996" misc_feature <47887..48168 /locus_tag="ClothDRAFT_1641" /note="FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038" /db_xref="CDD:73301" gene 48403..49077 /locus_tag="ClothDRAFT_1642" CDS 48403..49077 /locus_tag="ClothDRAFT_1642" /inference="protein motif:PFAM:PF07238" /note="PFAM: type IV pilus assembly PilZ; KEGG: geo:Geob_0640 type IV pilus assembly PilZ" /codon_start=1 /transl_table=11 /product="type IV pilus assembly PilZ" /protein_id="ZP_05429781.1" /db_xref="GI:256004806" /db_xref="InterPro:IPR009875" /translation="MRFNELGVGLKLELKLEGSDEKNGDSVFVSEFEWAENDRIIYIA APIKGGKIYPVSVGEELAIVFIKSDNLYEFKGKVIGREVRHNISLLRVETLSEIRKIQ RRDFFRFDCSIPISYRVVEKDRINILQRRFIKSYTRDISGGGVCIRLKERIETGELLE CELFLNDFNKVSFLGRVVRLTEYDSKNDVYKYEIGVKFEKIEERDRERIIGYIFQEQR RLIKKG" misc_feature 48706..49047 /locus_tag="ClothDRAFT_1642" /note="PilZ domain; Region: PilZ; cl01260" /db_xref="CDD:163963" gene 49087..50151 /locus_tag="ClothDRAFT_1643" CDS 49087..50151 /locus_tag="ClothDRAFT_1643" /inference="protein motif:PFAM:PF01339" /note="PFAM: CheB methylesterase; response regulator receiver; SMART: response regulator receiver; KEGG: net:Neut_1173 chemotaxis-specific methylesterase" /codon_start=1 /transl_table=11 /product="response regulator receiver modulated CheB methylesterase" /protein_id="ZP_05429782.1" /db_xref="GI:256004807" /db_xref="InterPro:IPR000673" /db_xref="InterPro:IPR001789" /translation="MIWNLKQKITVLVVDDSAFMRKVISDILNSDEEIKVIDTAKNGL EAIEKAQKLKPDVITLDLKMPVMDGLECLRKLNETMRIPVIMLSSITKEGAEATIQAL AEGAMDFVAKPENIFDMKEERIKNEIIEKVKIAKNYKYFKSDKKSTGTVIKANTTQSR IRNIVVIGTSTGGPRALQDVLPLFPANVDAAFLIVQHMPGGFTKSLAERLDSMCNVKV KEAEDDEIIENSHVYIAPGDFHMLLEKNGNDTFKIKLSKDPPLGGHRPSVDVMMESVS NTGFKNVVAVIMTGMGRDGSEGIKKLKSVNNAYIIAQDESSCVVFGMPRVAISTGVVD VVVPLKEIANEIMKIVGVHE" misc_feature 49108..50145 /locus_tag="ClothDRAFT_1643" /note="chemotaxis-specific methylesterase; Provisional; Region: PRK00742" /db_xref="CDD:179106" misc_feature 49120..49425 /locus_tag="ClothDRAFT_1643" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cd00156" /db_xref="CDD:29071" misc_feature order(49129..49134,49267..49269,49291..49293,49348..49350, 49411..49413,49420..49425) /locus_tag="ClothDRAFT_1643" /note="active site" /db_xref="CDD:29071" misc_feature 49267..49269 /locus_tag="ClothDRAFT_1643" /note="phosphorylation site" /db_xref="CDD:29071" misc_feature order(49276..49281,49285..49293) /locus_tag="ClothDRAFT_1643" /note="intermolecular recognition site; other site" /db_xref="CDD:29071" misc_feature 49420..49425 /locus_tag="ClothDRAFT_1643" /note="dimerization interface; other site" /db_xref="CDD:29071" misc_feature 49576..50133 /locus_tag="ClothDRAFT_1643" /note="CheB methylesterase; Region: CheB_methylest; pfam01339" /db_xref="CDD:144802" gene 50151..52229 /locus_tag="ClothDRAFT_1644" CDS 50151..52229 /locus_tag="ClothDRAFT_1644" /inference="protein motif:PFAM:PF01584" /note="PFAM: CheW domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; ATP-binding region ATPase domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; KEGG: nam:NAMH_0362 chemotaxis protein CheA" /codon_start=1 /transl_table=11 /product="CheA signal transduction histidine kinase" /protein_id="ZP_05429783.1" /db_xref="GI:256004808" /db_xref="InterPro:IPR002545" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004105" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR008207" /db_xref="InterPro:IPR010808" /translation="MDMSQYLEIFIDETKEHLQSLNQSLLELEQNPDDTSVLNEIFRV AHTLKGMSGTMGFTKMAKLTHDMENVLQALRNNQIKATSKLVDLLFKCLDALENYTDN IVNTGNEGSNEYNDIIKELNDIVQTKSSDGGQQKSSLSGKKVSDLDGTSKEENQHPTA AIKLNQYELNVAAKAREMNMNVFKITVVLNKGCVLKSARAFIIFQTLERHGEIIRSEP KVEDIEDEKFDFEFTVVCVTKENEEVFIKDINGIAEVDEVIVVPIDIPELKTSTVQND DNYERENVQTGGEEVHVQEEKSESNTSSQVHKTKTGKTVRVDIDRLDVLMNLVSELII IKTRLAGLSGSDNAQTYNETIEYLDRITTSLNDAVMKVRMVPVEMVFNRFPRMIRDIA RELGKEIQLNMSGVETELDRTVIDEIGDPLIHLLRNSADHGIEPKEKRLAMGKPAVGH INLRAYQDGDNVVIEVEDDGQGIDVEKVKKKAVEKGLVKKEIVNTLSQKDIIDFLFKP SFSTSDNITNISGRGVGLDVVKTKIEQLGGVVEVETEAGKGSKFIIRLPLTLAIIQAL LVMVGNEKYAIPLSSTKEIIKVTPEQIKTVQKQEVILLRNMVVPIVRLDKILEVPPVE RKKKDMTVVIVKKGEKLSGFLVDSLIGQQEIVIKSLGKLLSNIKGIAGATILGDGNVA LILDVNLLAV" misc_feature 50151..52220 /locus_tag="ClothDRAFT_1644" /note="Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643" /db_xref="CDD:30988" misc_feature 50157..50444 /locus_tag="ClothDRAFT_1644" /note="Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088" /db_xref="CDD:28972" misc_feature order(50286..50288,50295..50300,50343..50345,50352..50354) /locus_tag="ClothDRAFT_1644" /note="putative binding surface; other site" /db_xref="CDD:28972" misc_feature 50286..50288 /locus_tag="ClothDRAFT_1644" /note="active site" /db_xref="CDD:28972" misc_feature 50691..50909 /locus_tag="ClothDRAFT_1644" /note="P2 response regulator binding domain; Region: P2; pfam07194" /db_xref="CDD:148665" misc_feature 51087..51266 /locus_tag="ClothDRAFT_1644" /note="Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895" /db_xref="CDD:145841" misc_feature 51402..51818 /locus_tag="ClothDRAFT_1644" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature order(51420..51422,51432..51434,51441..51443,51546..51548, 51552..51554,51558..51560,51564..51569,51717..51728, 51774..51776,51780..51782,51795..51800,51804..51806) /locus_tag="ClothDRAFT_1644" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature 51432..51434 /locus_tag="ClothDRAFT_1644" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature order(51558..51560,51564..51566,51717..51719,51723..51725) /locus_tag="ClothDRAFT_1644" /note="G-X-G motif; other site" /db_xref="CDD:28956" misc_feature 51828..52220 /locus_tag="ClothDRAFT_1644" /note="CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731" /db_xref="CDD:29681" gene 52246..52710 /locus_tag="ClothDRAFT_1645" CDS 52246..52710 /locus_tag="ClothDRAFT_1645" /inference="protein motif:PFAM:PF01584" /note="PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: sat:SYN_00975 chemotaxis protein" /codon_start=1 /transl_table=11 /product="CheW protein" /protein_id="ZP_05429784.1" /db_xref="GI:256004809" /db_xref="InterPro:IPR002545" /translation="MEERANMESKQYVVFKLGKEDYGLDIQKVTTIERMMPAARVPKT PDYIKGVINLRGEIIPVMDLRKKFGLPPVEETDETRIIILKFDDITFGIIVDEVDEVL DLTEESIENVSSFSNDVSMDYIYGVGKVGDRIVTLLNLEKLTDIDEEDKQGD" misc_feature 52276..52689 /locus_tag="ClothDRAFT_1645" /note="CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732" /db_xref="CDD:29682" misc_feature order(52402..52419,52501..52503,52507..52509,52666..52689) /locus_tag="ClothDRAFT_1645" /note="putative CheA interaction surface; other site" /db_xref="CDD:29682" gene 52685..53335 /locus_tag="ClothDRAFT_1646" CDS 52685..53335 /locus_tag="ClothDRAFT_1646" /inference="protein motif:PFAM:PF04509" /note="PFAM: CheC domain protein; KEGG: gsu:GSU3200 chemotaxis protein CheC" /codon_start=1 /transl_table=11 /product="CheC, inhibitor of MCP methylation" /protein_id="ZP_05429785.1" /db_xref="GI:256004810" /db_xref="InterPro:IPR007597" /translation="MKKTNKGIRKMSVNFDNLDNIQIDVLREIGNIGSGNAATALAKM LNKRVNMDVPQVKVLQFQEVSDILGGAEIPVVGLLLRVTGDISGSIMFILEKKAAGVL VNILMGKPLDEIVVFDEIAISALKEVGNILAGSYLSALSTLTNLNILPSVPELAIDMA GAIISVPAIEFGKLGDSVLFIETEFSEGSTKVVGNFFLVPDIDSYEVLLKALGVAN" misc_feature 52724..53326 /locus_tag="ClothDRAFT_1646" /note="Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776" /db_xref="CDD:31962" misc_feature 52745..52858 /locus_tag="ClothDRAFT_1646" /note="CheC-like family; Region: CheC; pfam04509" /db_xref="CDD:113285" misc_feature 53042..53155 /locus_tag="ClothDRAFT_1646" /note="CheC-like family; Region: CheC; pfam04509" /db_xref="CDD:113285" gene 53335..53820 /locus_tag="ClothDRAFT_1647" CDS 53335..53820 /locus_tag="ClothDRAFT_1647" /inference="protein motif:PFAM:PF03975" /note="stimulates methylation of MCP proteins; PFAM: CheD family protein; KEGG: gme:Gmet_3209 CheD, stimulates methylation of MCP proteins" /codon_start=1 /transl_table=11 /product="CheD" /protein_id="ZP_05429786.1" /db_xref="GI:256004811" /db_xref="InterPro:IPR005659" /translation="MGNIIRIGMADLKASHHPAILTTLGLGSCVGIALYDRTTKIVGL AHAMLPDSSQVKNKTNAAKFVDTAIELLVKEMLSLGASKKRIVAKLAGGAQMFTFTQG AELMRIGQRNVAAAKSKLESLDIPVVSEDTGGNYGRTVELDSESGMLLIRTIGYGTKQ I" misc_feature 53344..53817 /locus_tag="ClothDRAFT_1647" /note="CheD; Region: CheD; cl00810" /db_xref="CDD:186200" gene 53835..54233 /locus_tag="ClothDRAFT_1648" CDS 53835..54233 /locus_tag="ClothDRAFT_1648" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429787.1" /db_xref="GI:256004812" /translation="MDYMRKMPFIMGASAAIVIGIISYNNGYDLKAICVRMTAGMILF FAAGVLLRKVINSIYEEVKEKSELQIHNTNESQNTGKKEHEKNHGIDYRVGDETPNLK NNEKIEDNVLYDEEFRPLEASRVTVKDDKQ" gene 54286..55056 /locus_tag="ClothDRAFT_1649" CDS 54286..55056 /locus_tag="ClothDRAFT_1649" /inference="protein motif:TFAM:TIGR02479" /note="TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 3 domain protein; KEGG: bba:Bd3318 RNA polymerase sigma factor for flagellar operon" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma 28 subunit, FliA/WhiG" /protein_id="ZP_05429788.1" /db_xref="GI:256004813" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR012845" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR014284" /translation="MASASNKQLELWKQYADTKNPAIKEQLIIEYSNIVKYIAGRLSI YFGSNVEYDDLIGYGIFGLIDAIEKFDINKGVKFETYASLRIRGSIIDSIRELDWVPR SLRQKNKELEKVYAEIENELGRSASDKEVADKLGITVDELNKLLNEVNLSSMISLEEF LEQNYEIGVTTAPESRDEKPEGYIEMAELREILADAISKLPEKEKMVITLYYFEDLTL KEISAIMKVSESRISQLHTKAILRLRGKLARHKSILSD" misc_feature 54313..55050 /locus_tag="ClothDRAFT_1649" /note="RNA polymerase sigma factor WhiG; Reviewed; Region: PRK06288" /db_xref="CDD:180512" misc_feature 54364..54582 /locus_tag="ClothDRAFT_1649" /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542" /db_xref="CDD:146937" misc_feature 54601..54789 /locus_tag="ClothDRAFT_1649" /note="Sigma-70 region 3; Region: Sigma70_r3; pfam04539" /db_xref="CDD:146934" misc_feature 54853..55017 /locus_tag="ClothDRAFT_1649" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cd06171" /db_xref="CDD:100119" misc_feature order(54886..54888,54916..54918,54934..54939,54967..54969, 54973..54978,54982..54990,54994..54999,55003..55005) /locus_tag="ClothDRAFT_1649" /note="DNA binding residues" /db_xref="CDD:100119" gene 55096..56724 /locus_tag="ClothDRAFT_1650" CDS 55096..56724 /locus_tag="ClothDRAFT_1650" /inference="protein motif:PFAM:PF03961" /note="PFAM: protein of unknown function DUF342; KEGG: gme:Gmet_3025 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF342" /protein_id="ZP_05429789.1" /db_xref="GI:256004814" /db_xref="InterPro:IPR005646" /translation="MRDVTKGSFNDSPNNGFFEIQYKEDGVYLTVHPPIGKGKAVEVN DVISRLTQKKIVYDKEMVELAVQRASNVPVKIGEPQEELKLDATIDVNISPDKMKATM VIRPPDGGRMLTKDEMMEILKNSGVRYGINESMLENVSKYPVYNEIIVIAEGTPPING QNGKVEFHFDLKKERKPTILEDGRVDFRELNLIESVKKGQVLCTLVPPLPGTPGRTVE DIEVPALDGKPAVLPKGKNVEISEDGQSLIAGIDGQVNYIDGKVSVFANYEVPADVDN STGNISFVGNVIIRGNVLSGFTVEAGGSVEVMGVVEAAVIKADGDIILRRGMQGLGRG ILKSGGDIIAKYIENSIIEAKGDIKAEAIMHSNVKCGNKLELSGKKGLLIGGKCKVGK EIVAKVIGSYLATHTDIEVGVDPQIKERYKELRDEIRKIEEDLVKAEQAITILKKLEA AGKLTPEKQELMARSIRTKIYYSNRLGELKEELIITEQRLQKEADGKIRVFDHIYPGT KVTIGTSMMYVKEDLQYCTLYRDGADIRVGPIDK" misc_feature 55360..56700 /locus_tag="ClothDRAFT_1650" /note="Protein of unknown function (DUF342); Region: DUF342; pfam03961" /db_xref="CDD:146542" gene 56751..57062 /locus_tag="ClothDRAFT_1651" CDS 56751..57062 /locus_tag="ClothDRAFT_1651" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429790.1" /db_xref="GI:256004815" /translation="MSIKPIDFQMMIPKTAEISKIQNDQQQKSVVVNEQQTNITRQKF EENVNTVHARENAEKVRIDSEQKKKKEERGRKKNPNRAKYGTKGEKEPEEQTSVIDIR L" gene 57098..57682 /locus_tag="ClothDRAFT_1652" CDS 57098..57682 /locus_tag="ClothDRAFT_1652" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429791.1" /db_xref="GI:256004816" /translation="MTGFYASMMFIGILLIIVSLVLIFLDKWKSSETEKRIDQKREEL AKIIADADLMVQELNKFSDYIISQVEQKNKETLDLIKNAEERLEKLTKEYASASMDSG NEKFVTNTEDSYAGGKSDLVIENLKFEEDAPVSAAKPYQIKLQGVKDEKVIPINSKHK EVLALAQKGLNETEIAKKLSMGKGEIQLILGVNK" misc_feature <57197..57427 /locus_tag="ClothDRAFT_1652" /note="Fe-S protein assembly chaperone HscA; Region: HscA; TIGR01991" /db_xref="CDD:162645" gene 57714..58343 /locus_tag="ClothDRAFT_1653" CDS 57714..58343 /locus_tag="ClothDRAFT_1653" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429792.1" /db_xref="GI:256004817" /translation="MGRFHIKNILLGIGMGLVLTALTGIIYSAGREPQMSKEEIMAKA RQYGMVPSNEIIEESENELVDEEEAEVEPAGKQVDNENIQVHASDGLENNEEMKSQPT QNPEVTKDVPVQPTANPDNAENVQIQPASTPENVEKRQVKIKIAPGDNSYVISKKLVE EGLIDNANSFINEIRAMKLQTSIQVGEYTIEEGTDIKTIIRIICKRKKI" sig_peptide 57714..57800 /locus_tag="ClothDRAFT_1653" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.866) with cleavage site probability 0.433 at residue 29" misc_feature 58134..>58292 /locus_tag="ClothDRAFT_1653" /note="YceG-like family; Region: YceG; pfam02618" /db_xref="CDD:145655" gene 58506..58841 /locus_tag="ClothDRAFT_1654" CDS 58506..58841 /locus_tag="ClothDRAFT_1654" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429793.1" /db_xref="GI:256004818" /translation="MLSVDVLLCIKIKSFRKEVDGLRSKIIVLAALIQLILFSGCMSS ELVLGPKKEVSLYSEKIVEAGGPLVLDIFCDSGNIEMYTWDKDGVKFEMTKRVRGTES EEILSQKTQ" gene 58810..59373 /locus_tag="ClothDRAFT_1655" CDS 58810..59373 /locus_tag="ClothDRAFT_1655" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: bba:Bd3636 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429794.1" /db_xref="GI:256004819" /translation="MKRFCLKKLNNFNIDINENENKIIFKSEYKGKDKNPIDKSIDLK IYVPKAEKTLNLKLDIGNIKFYDDIKGVLNADINMANMEINRFVGVVNIEGDVGNVKI SSGKISGKSSIVKNIGNISVKAEFEEGGDYTFKTGTGNIDLMLPYGSKVSFESVGELE VNEFNDFNHSTKAKVETSMGKIAITGY" gene 59525..60076 /locus_tag="ClothDRAFT_1656" CDS 59525..60076 /locus_tag="ClothDRAFT_1656" /inference="protein motif:TFAM:TIGR02258" /note="TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: sfu:Sfum_2529 2'-5' RNA ligase" /codon_start=1 /transl_table=11 /product="2'-5' RNA ligase" /protein_id="ZP_05429795.1" /db_xref="GI:256004820" /db_xref="InterPro:IPR004175" /db_xref="InterPro:IPR014051" /translation="MRTFVAVDFNTELKKEILKLQTQLRNLAVSGRWKYIDNFHLTLK FLGEIEKSKVQDIKKGLDEVCGKTQKFCLNIDGLDFFPGNGCLRVLWLKLAGELESLH SLQSEIDIMLEKLGFEKEKRRYVPHVTIAQDVVFNKDFEEIKGLVGNYRFATIEVQSV NLFKSEQIGGKRVYTPLTEHKLV" misc_feature 59525..60055 /locus_tag="ClothDRAFT_1656" /note="2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258" /db_xref="CDD:162789" misc_feature 59543..59797 /locus_tag="ClothDRAFT_1656" /note="2',5' RNA ligase family; Region: 2_5_RNA_ligase; pfam02834" /db_xref="CDD:145803" gene 60178..61413 /locus_tag="ClothDRAFT_1657" CDS 60178..61413 /locus_tag="ClothDRAFT_1657" /inference="protein motif:COG:COG2843" /note="KEGG: gsu:GSU0036 capsule biosynthesis protein, putative" /codon_start=1 /transl_table=11 /product="Putative protein of poly-gamma-glutamate biosynthesis (capsule formation)-like protein" /protein_id="ZP_05429796.1" /db_xref="GI:256004821" /translation="MRKKYVALAVIVFLIGISALGGCNFRSDSVAVVNEKNTGTYEND LDQKKVADAAKDGTVGTVSETVYSTVQPTATPEKELKIVAVGDILLGRGVGMRLKNGN KDFTYPFLEVRYILRKGDVVFGNLEEPITSSTHSLTGIKEGGKYVLKNDVEAIEGIKY AGFNLMNLANNHILDYYERGLFDTMDILDKNGIKYAGAGRNLEEARKPAIMEVKSMKV GMLAYTDMAEIVYKGNPNYKFAAGEDKPGVAPRPLKFDDSIKKDIEELRSKVDILIVS LHWGVEESFEVLPEQREFAHSLIDNGVDVILGHHPHQFQGIEIYKGKPVFYSLGNFIF DQNDPENQESFIVTLDYKGSRLTGIEAVPVRTIGKIQVVPQKGDEAKPILEREKNLCN RLDTNCIIKDDKLYFEIGK" sig_peptide 60178..60246 /locus_tag="ClothDRAFT_1657" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.942) with cleavage site probability 0.377 at residue 23" misc_feature 60418..61185 /locus_tag="ClothDRAFT_1657" /note="Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854" /db_xref="CDD:129087" misc_feature 60421..61179 /locus_tag="ClothDRAFT_1657" /note="CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381" /db_xref="CDD:163624" misc_feature order(60436..60438,60442..60444,60556..60558,60688..60693, 61009..61011,61105..61107,61111..61113) /locus_tag="ClothDRAFT_1657" /note="putative active site; other site" /db_xref="CDD:163624" misc_feature order(60436..60438,60442..60444,60556..60558,60688..60690, 61009..61011,61105..61107,61111..61113) /locus_tag="ClothDRAFT_1657" /note="putative metal binding site; other site" /db_xref="CDD:163624" gene 61799..64027 /locus_tag="ClothDRAFT_1658" CDS 61799..64027 /locus_tag="ClothDRAFT_1658" /EC_number="2.3.1.54" /inference="protein motif:TFAM:TIGR01255" /note="KEGG: rpc:RPC_1080 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical" /codon_start=1 /transl_table=11 /product="formate acetyltransferase" /protein_id="ZP_05429797.1" /db_xref="GI:256004822" /db_xref="InterPro:IPR001150" /db_xref="InterPro:IPR004184" /db_xref="InterPro:IPR005949" /translation="MDAWRGFNKGNWCQEIDVRDFIIRNYTPYEGDESFLVGPTDRTR KLWEKVSELLKKERENGGVLDVDTHTISTITSHKPGYIDKELEVIVGLQTDEPLKRAI MPFGGIRMVIKGAEAYGHSVDPQVVEIFTKYRKTHNQGVYDVYTPEMRKAKKAGIITG LPDAYGRGRIIGDYRRVALYGVDRLIAEKEKEMASLERDYIDYETVRDREEISEQIKS LKQLKEMALSYGFDISCPAKDAREAFQWLYFAYLAAVKEQNGAAMSIGRISTFLDIYI ERDLKEGKLTEELAQELVDQLVIKLRIVRFLRTPEYEKLFSGDPTWVTESIGGMALDG RTLVTKSSFRFLHTLFNLGHAPEPNLTVLWSVNLPEGFKKYCAKVSIHSSSIQYESDD IMRKHWGDDYGIACCVSAMRIGKQMQFFGARCNLAKALLYAINGGKDEMTGEQIAPMF APVETEYLDYEDVMKRFDMVLDWVARLYMNTLNIIHYMHDKYAYEALQMALHDKDVFR TMACGIAGLSVVADSLSAIKYAKVKPIRNENNLVVDYEVEGDYPKFGNNDERVDEIAV QVVKMFMNKLRKQRAYRSATPTLSILTITSNVVYGKKTGNTPDGRKAGEPLAPGANPM HGRDINGALAVLNSIAKLPYEYAQDGISYTFSIIPKALGRDEETRINNLKSMLDGYFK QGGHHINVNVFEKETLLDAMEHPEKYPQLTIRVSGYAVNFIKLTREQQLDVINRTIHG KI" misc_feature 61805..64024 /locus_tag="ClothDRAFT_1658" /note="formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255" /db_xref="CDD:162272" misc_feature 61805..64015 /locus_tag="ClothDRAFT_1658" /note="Pyruvate formate lyase 1; Region: PFL1; cd01678" /db_xref="CDD:153087" misc_feature order(62123..62128,62210..62215,62222..62227,62231..62233, 62246..62248,62255..62260) /locus_tag="ClothDRAFT_1658" /note="coenzyme A binding site; other site" /db_xref="CDD:153087" misc_feature order(62303..62305,62579..62584,62744..62746,62762..62764, 63014..63016,63056..63058,63065..63067,63572..63574, 63578..63580) /locus_tag="ClothDRAFT_1658" /note="active site" /db_xref="CDD:153087" misc_feature order(63014..63019,63947..63949) /locus_tag="ClothDRAFT_1658" /note="catalytic residues; other site" /db_xref="CDD:153087" misc_feature 63938..63952 /locus_tag="ClothDRAFT_1658" /note="glycine loop; other site" /db_xref="CDD:153087" gene 64054..64770 /locus_tag="ClothDRAFT_1659" CDS 64054..64770 /locus_tag="ClothDRAFT_1659" /EC_number="1.97.1.4" /inference="protein motif:TFAM:TIGR02493" /note="KEGG: son:SO_2913 pyruvate formate lyase-activating enzyme 1; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB" /codon_start=1 /transl_table=11 /product="pyruvate formate-lyase activating enzyme" /protein_id="ZP_05429798.1" /db_xref="GI:256004823" /db_xref="InterPro:IPR001989" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR012838" /translation="MTLKGRIHSFESFGTLDGPGIRFVVFMQGCPLRCIYCHNRDTWD VNAGSEYTPRQVIDEMMKYIDYIKVSGGGITVTGGEPVLQADFVAEVFRLAKEQGVHT ALDTNGFADIEKVERLIKYTDLVLLDIKHAREDKHKIITGVSNEKIKRFALYLSDQGV PIWIRYVLVPGYTDDEDDLKMAADFIKKLKTVEKIEVLPYHNMGAYKWEKLGQKYMLE GVKGPSAQEVEKAKRILSGK" misc_feature 64069..64758 /locus_tag="ClothDRAFT_1659" /note="pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493" /db_xref="CDD:131546" misc_feature 64123..64665 /locus_tag="ClothDRAFT_1659" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(64141..64143,64147..64149,64153..64155,64159..64167, 64282..64284,64288..64293,64366..64374,64441..64443, 64552..64554,64648..64653) /locus_tag="ClothDRAFT_1659" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene complement(64790..65437) /locus_tag="ClothDRAFT_1660" CDS complement(64790..65437) /locus_tag="ClothDRAFT_1660" /inference="protein motif:PFAM:PF00929" /note="PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: hch:HCH_00811 inhibitor of the KinA pathway to sporulation, exonuclease" /codon_start=1 /transl_table=11 /product="Exonuclease RNase T and DNA polymerase III" /protein_id="ZP_05429799.1" /db_xref="GI:256004824" /db_xref="InterPro:IPR006055" /db_xref="InterPro:IPR013520" /translation="MNYIVYDLELNSKPFKSSIPNEIIEIGAIKLNENLQEIGMFSSF IKPKYFKKLFSVVKQKTKITQEQINSADSFRNVIKQFIRWIGDDYLLISWGHDDVLNL ILNCKFNRIKIDWLKRNIDIQKQFSAIYHLPSGQRYSLENALALIGVEIDENLHRALT DAQYTAKIFKSIFDKLDLEVYNTVHIKDKYKRNIKKLIKTKPKLKQSKLVIEKSK" misc_feature complement(64919..65431) /locus_tag="ClothDRAFT_1660" /note="DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133" /db_xref="CDD:99836" misc_feature complement(order(64955..64957,64970..64972,65132..65134, 65144..65158,65270..65272,65402..65404,65408..65419)) /locus_tag="ClothDRAFT_1660" /note="active site" /db_xref="CDD:99836" misc_feature complement(order(64955..64957,64970..64972,65132..65134, 65144..65158,65270..65272,65402..65404,65408..65419)) /locus_tag="ClothDRAFT_1660" /note="substrate binding site; other site" /db_xref="CDD:99836" misc_feature complement(order(64955..64957,64970..64972,65144..65146, 65411..65413,65417..65419)) /locus_tag="ClothDRAFT_1660" /note="catalytic site; other site" /db_xref="CDD:99836" gene 65693..66103 /locus_tag="ClothDRAFT_1661" CDS 65693..66103 /locus_tag="ClothDRAFT_1661" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429800.1" /db_xref="GI:256004825" /translation="MKLKFGVIILAVFLLAGCSSNINYDDKNNVEFTRLNQENTLDVG SDQIRILSANTTVGYEEYASISIIGKPEETYTITSRYKWGGEDVTVVEKRKANRDGVA TWVWKVRSNTIPGTYPIVITGGNQRIETSYTVRP" sig_peptide 65693..65764 /locus_tag="ClothDRAFT_1661" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.909) with cleavage site probability 0.454 at residue 24" gene complement(66222..66383) /locus_tag="ClothDRAFT_1662" CDS complement(66222..66383) /locus_tag="ClothDRAFT_1662" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429801.1" /db_xref="GI:256004826" /translation="MKINWEVFSSGINVALLGLAGVFTVLILFYIITKLLLYFCNKFD KENSNPDNV" misc_feature complement(<66246..66362) /locus_tag="ClothDRAFT_1662" /note="Oxaloacetate decarboxylase, gamma chain; Region: OAD_gamma; cl01458" /db_xref="CDD:186433" gene complement(66401..67510) /locus_tag="ClothDRAFT_1663" CDS complement(66401..67510) /locus_tag="ClothDRAFT_1663" /EC_number="4.1.1.70" /inference="protein motif:TFAM:TIGR01109" /note="KEGG: sfu:Sfum_3585 sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit" /codon_start=1 /transl_table=11 /product="sodium ion-translocating decarboxylase, beta subunit" /protein_id="ZP_05429802.1" /db_xref="GI:256004827" /db_xref="InterPro:IPR005661" /translation="MQELLKGILCMSWQNIAMFIIAGILIYLAIAKEYEPTLLLPIGF GTILANIPFSNALGEEGVLSILYNAGIKTELFPVLIFIAVGAMIDFGPLLKNPFMLFF GAAAQFGIFATMLVATLLGFDLAEAATIGIIGAADGPTSIVVAQKLAPGLIGPITVAA YSYMSLVPIIQPPVIKLLTTKKERLIRMEYTEEKVPKSVKILFPIIVTLLAGLIAPSS VALVGFLMFGNLIRECGVLERLSKSAQNELANIVTILLGITIGSTMVGEQFLNKRTLL IIGLGLVAFIFDTAGGVIFAKILNLFLKKKINPMIGAAGISAFPMSARVVQQLATKED PTNFIIAQSISANVSGQLGSIVAGGMILALVPLFM" misc_feature complement(66416..67474) /locus_tag="ClothDRAFT_1663" /note="subunit; Region: OAD_beta; cl00816" /db_xref="CDD:186204" gene 67775..69280 /locus_tag="ClothDRAFT_1664" CDS 67775..69280 /locus_tag="ClothDRAFT_1664" /inference="protein motif:PFAM:PF02518" /note="PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: scl:sce0817 two-component hybrid histidine kinase" /codon_start=1 /transl_table=11 /product="histidine kinase" /protein_id="ZP_05429803.1" /db_xref="GI:256004828" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /translation="MDGNTLELIFSCANRNLCDGKIEKDEKEGKPGKIKCFNCNKKLC RFSNLTNTAIIKEKVPTMNIKKDLKKPYPLKLKKSGRKLLAERYYQILRRKYNCLYEI FNSIELPIVSISYPSFNIIGINNKAKKDVKLLRKCVAFVREVKKGNNILNALSKVYSC RNQKYLAEMLFTKSPVYLPNVEIDNNGRKIYYKLMHQPILNSRNKIVGFLIIPIDITQ EIEQKKYIENLARFKDEFLYGITHEFKTPLVVISSALQAIEALCRDELTDRVKKYLNR IKQNTFRQIRLVNNLLDIARIEAGHIKIFKRNLDIVALTRLITESVSMFADLKGVQLL FYSNIDKKIIAIDEEKYERIMLNLLSNAIKFTPKDRSVYVEVSAKEGCVEIKVKDSGI GIPKDKIKTIFERFGQVDSSLSRNAEGTGIGLSLVRMFVNAMGGEISVTSEENIGSTF TVTLPDAVTECGYENDCFDDLRDERLIQAIKIEFSDIYFEEKEDKKKSLET" misc_feature 68465..68662 /locus_tag="ClothDRAFT_1664" /note="Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-...; Region: HisKA; cd00082" /db_xref="CDD:119399" misc_feature order(68480..68482,68492..68494,68504..68506,68513..68515, 68525..68527,68534..68536,68591..68593,68603..68605, 68612..68614,68624..68626,68633..68635,68645..68647) /locus_tag="ClothDRAFT_1664" /note="dimer interface; other site" /db_xref="CDD:119399" misc_feature 68498..68500 /locus_tag="ClothDRAFT_1664" /note="phosphorylation site" /db_xref="CDD:119399" misc_feature 68828..69136 /locus_tag="ClothDRAFT_1664" /note="Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075" /db_xref="CDD:28956" misc_feature order(68843..68845,68855..68857,68864..68866,68933..68935, 68939..68941,68945..68947,68951..68956,69035..69046, 69092..69094,69098..69100,69113..69118,69122..69124) /locus_tag="ClothDRAFT_1664" /note="ATP binding site; other site" /db_xref="CDD:28956" misc_feature 68855..68857 /locus_tag="ClothDRAFT_1664" /note="Mg2+ binding site; other site" /db_xref="CDD:28956" misc_feature order(68945..68947,68951..68953,69035..69037,69041..69043) /locus_tag="ClothDRAFT_1664" /note="G-X-G motif; other site" /db_xref="CDD:28956" gene complement(69305..69380) /locus_tag="ClothDRAFT_R0033" /note="tRNA-Lys2" tRNA complement(69305..69380) /locus_tag="ClothDRAFT_R0033" /product="tRNA-Lys" gene 69579..69665 /locus_tag="ClothDRAFT_R0032" /note="tRNA-Leu2" tRNA 69579..69665 /locus_tag="ClothDRAFT_R0032" /product="tRNA-Leu" ORIGIN 1 agatgaggaa aatactattt atttggactt tgtgcaatac tttttgtctg tacaattgta 61 tttttcatat ataataaagt aaatacaata aagataacat ttaatccgga tgaagtttat 121 cttatttcta ttggtatacc ggaagcgagt gtatatacga aagatagagg caaaataaac 181 aaaataatta aatatttaaa ttcgtttagt tattctgatg gttctgacct aaaattgcct 241 aatgatagcc ccgatatatt tgtgtttatg tatgatgaaa atgaaaaagt aattgaccga 301 cttatgatat atggaaaggt aatagtatat aaagacaata aatacaaagc tcctttcctt 361 tttgattata ggtttgagag gttttgcaag agattaaatg aagacaataa tgaaagcaat 421 taagtaaaac taaattttac tacacaactg agagtcttgg agattgcttg ttgtaaaatg 481 tatactatta ccatcagtaa agttaaaaat atgcaaactg tttcaattga aaattgggca 541 agtgaatgga tacataaaaa ataaaaccca atatgaatat atattatata aaatctattt 601 aagccacgca gttgataaaa gaaaagataa aaaggtgacc ttgttactct gccaaggtca 661 ccccattatt cttttaatcg ttgtatcatg ggccaggttt tcaaattcat cgtcaatacc 721 agataacgac acaaaatcct tgtatttctg ttttaaggcg acagaaataa gatggtcggc 781 caaggccggg tttttgggaa gcagacttcc gtgggaataa gagcagtaaa catttttgta 841 aatggctcct tcaaaaccgt cttctccgtt gtttccatag ccttttataa tcttgccgag 901 aggctttact ccaggaccta aataggttct tccggaatga ttttcaaagc ctacgatttt 961 tccatcataa tggtcattct ttaaaaaatc gcattcaaac acaaagtttc cgatcattct 1021 ttccttgccg cctatggtcc ataagtccag agcgttcaga aagtgaattt ccttaccgtc 1081 ccacgtttta taataactgc ctaaaagctg atatccgccg caaattgcca gaaacacttt 1141 gtcatttttt acggcgttcc tgatttcctc tcctttttgg tttaggaggt catcttggat 1201 tatttcctgt tcataatcct gaccgccgcc caaaaatata atgtcgtagg cttcggcgtc 1261 aaacttgtcc ccgatggata tgtttgaaac gtttacgttt attccgcgcc atacgcagcg 1321 cattttcaaa gccattatat ttcctctgtc accatacaaa ttcaaaaggt cagggtataa 1381 atgacaaata ttcagctcat acatattatt tccaaaactc ctttaaaccg aattttttct 1441 ccagaaggct tcttacttca agcattgcgg tataggtggg cagtatataa agattctgcc 1501 cttctgaagt agtggctaaa gctttattga gaagctcttc atagtctttt tcaatctgaa 1561 tcttatcgat gtttattcct gcatatttaa gccttacagc catatcctcc gcacggattc 1621 ctgaagcata aaagctggat actttgtcct gcatttgctg aagctgctca aaatcaacat 1681 cccacagcca cgaaatatcg gtgccgtctg caaggcggtc atttataaca aaggctattt 1741 gagtattttg cttttccgta agaagataac ttaaaacctg attaaagccg gttgggtttt 1801 taaccagaat aacctttatg gttttaccgt cggtttcgat ggtttccatt cgtccaaaac 1861 cgcattcgaa actttccatg gcttttacaa ggctttccgg cgaaaagcct gaaagatgtc 1921 ccagggacgc cgcagccagt gcgttatata tgttataaag tccgggaaga ttaattctgg 1981 cgttgtatga aaccggctcg tcattgccct ttattggact taatgaaaat atgatatcgg 2041 aatacgaagt gttaagctcg ttaattttta cgcatgttac cttggaatca ggtcgcatat 2101 atccgcagtt tggacaggaa aatcccccaa gatggccata tacattgtag gagtactcat 2161 atttgctttt gcagtaaagg caaatgcttg catcactgtt tacaactgtg ctgctgttgt 2221 tgtacgcttc ctcagaaaaa ccgtagtata tggcctctct gtccatattg tgacctaatg 2281 atgcacaaag agagtcgtct gcatttaaaa ccagcttgac attcggtgac ttttcgatgc 2341 ctgatctgac attgcttaca gtggtgtaga gctcaccata tcggtccaac tggtccctga 2401 aaaagtttgt taccaccaaa acatccggct gaacgtagtc ggttaccaca ttgaaggcag 2461 cctcgtcaac ttccagcaat gctgtggaag ttttgctttt tccgaaaata tttacagatt 2521 caataaaagt ggtaataata ccgcttacca gattggcacc ggatttgttg gtaatgtact 2581 ctatattgtt ttcctcaagt acttttccga ttatacgggt agtggtggtc ttgccgtttg 2641 ttcccgtaac cattattatt ttaaaatctt ttgaaattac cttaattatg tccgggtaaa 2701 ttttatacgc gacttttccc ggaagagaag ttcctcccct ttttaaaatt cttaatgcaa 2761 gaataaggag ttttgtaaca attattgtga aaataagtct tatattcatc tgtatccctg 2821 ctttttcttt tgtatttttc gcttaatttc tttaaaatta taacataaag agttttactt 2881 atgaacaaat atttttctta gggaagtatt tcccgaaata attagttgat atacccacta 2941 aaatctcccc cattaaaaaa catttgatac atatttttta aaatgataaa ataatgaata 3001 aagattgttt aatgcattaa aagctgaatt ataatcttca tttatggtac aataagatta 3061 gccacccggg tgggtgtgaa ataggtccgc ggccgattga ccttcatatc aaggctctga 3121 aacggatggg ggtcaaggtg cacgatgcac atcacggatt tttatactgt gaagttgata 3181 aaattaaagg atgcgagatt caactggatt ttcccagtgt gggagccaca gagaatataa 3241 tgctggctgc ggtttttgcc gagggcgaga ctgttatacg gcatgcagcc aaggagcctg 3301 aaatcgtaga ccttcagaat tttcttgtag gaatgggtgc ggatgtgtca ggagcgggaa 3361 ccagtaccat aacgatacga ggtacgaaca ggaaacttaa taatgttgag cacactgtta 3421 tacccgacag gatagttgca ggtacatatt tggtggcggc agggattacc ggaggagaat 3481 tgaatctaaa gaatgttatg ccggagcata taacgtccgt ggtgtcatat cttcgggaaa 3541 gcggatgcag gatcaacata aaacggaaca atatacatat ttcaggtccc agcaggccga 3601 aggctattga cataatcagg actctgccat atccgggttt tcccaccgat atgcagtcgc 3661 agtttgtttc tctgctttcg gttgccagag gaaccagcat tatagttgag accatatttg 3721 agaaccggta caaacatgtt gaggaactat tgagaatggg agccgacata aagcttgaag 3781 gaaggctggc ggtaataaaa ggagtaaaaa ggcttaccgg ggcaactgtt acagccaggg 3841 acttaagagg aggagctgct ttggttcttg cggcgctggc agctgaaggt accagcataa 3901 taagcggaat aaaacatatc gacagaggtt atgaaaatat tgaaggaaag ctttccatgg 3961 tcggagctat aattaaaaga gaagaataaa ggggtaagtc cgttgaagat acatgagata 4021 acaaccgttg cagagtatca gccgcaaaga aaacacaaaa gaaaaaaaag aaaaaaatac 4081 tttcattttt taaatttata ttgataagtg ggatttttgc ggctatttta gtatgcgttg 4141 gtttgtctcc attattttct gtaaatagga ttgaagttta tggcaataag cattataata 4201 gcaatgaagt gattgaagct tcaggtttgg taataggcaa taactggttt aaatccaaca 4261 gtgtgaatct gaaaggaata cttactttca gatcaattga tgcggaaaac cttttgctta 4321 acagatgtcc gtatttaaaa agtgcgatag tgaaaataga ctttacgggt gtggttcgta 4381 ttgaagtaac tgaaagggat cctgttgctt tggtgcccta tatgggtgcg aatcttgtga 4441 ttgacaatga gtgttttgtg cttgctctaa gcagcaatgc tgaggacgaa aaactgcctg 4501 tgataaaagg agtagattgc gaaggttata ctttgggaca ggctttaccg acgcataacc 4561 caaaatgttt ggaagctttt cgcagggtaa tgaaggttat tgagtccgct gattccaatt 4621 ccggggaaag gggcaaagaa tacggtataa aaggtataat aaactatatt gatgtatctg 4681 atcttgacaa tattaaactc taccttgact ccaggatatt ggttaatctt ggaaactata 4741 aagatataag tgaatataga atcaatttct taagagagat attttacttc cagttaacaa 4801 aggaagacaa gggtttgctg gattttgcat cgggtgaata tccgagtttt ataccagatt 4861 agagagggag gagcggaatg attcctttat ttggtttgat tattggaatt ttgattggaa 4921 tatttattcc atacagtatt cctgagcagt attcaagcta tgtggcagta gctattcttg 4981 cggcactgga ttctgttttt ggaggtattg tttccaccat ccagaagaag tttgatatgg 5041 gaatttttct gtcaggcttt ttcggaaatg ctcttttggc tgccgcactt acttatatag 5101 gggacaagct tggaatacaa atttatttcg ctgcgatatt tgcttttgga aacagactgt 5161 ttttaaattt tgctgttatt cgaagatttc tattgaataa gttaaccaaa aaggataata 5221 ttaaagataa tatgatggaa actaaagaag cttaaaatct tttacataaa tgttaatggc 5281 ataatggtgt tcaggcaaga cttttgattt tcaaaagtaa aatttttact atgtcaaggt 5341 caacaagaat aaaaactgct gataatgtat ggcgattgat aagtattcgt actttggcat 5401 acaggaggtt tacataagtg gatgatataa tcagttgtat tgatataggt actacaaaag 5461 tatgtgccat tgtagcgaaa cttgatgaga acggcaatgt tgaaatattg ggcagggcga 5521 ctgaaccgtg cagcggtgtg aaaaaaggtg taattgttga tatagacagt gtttccaatg 5581 ccttaaaaag ttgtgctcaa aagataaggg ctttgcttaa tattgacatt gagaatgttt 5641 atgtaaacgt catggggtca catgttgatg ttttttttaa caaagctgcg gttgatattt 5701 taaggccgga ccgtcaaatt acatccgaag atgttgagag aacgctgaaa aaggttgagg 5761 atgtaaagct tcctgataat gttcagatta ttgatgttat tccaagacag tatattgtgg 5821 acggttgtga tgaaatagtt gaccctgtcg gaatggcggg agtgaagctt gaacttgaag 5881 cggatgttgt agttggaaaa atcactacct tcaacaatat tataaaaagc ctcgacaacg 5941 ccaatatcaa agtaaatggc tttattgcgg aagcattggc ggtgggtgat ttggttttaa 6001 gtccggagga aaaagatata ggcgcaattc ttattgacgt cggcggagga gttacaaaca 6061 tatccgtgtt caaaaacaag tgtctcgccc tgtatgattc catacctgtc ggaggagacc 6121 atataacaaa cgatatatcc attggactta aagtatcatt gaatgatgct gaaaaactaa 6181 aacgggatta tggtttggct cttacttcac ttattgacaa cgaccatgac ataacaataa 6241 atgagtttag cgagaacacc aaaagaacga taaaggtttc cgaagttgtt gaaataatcg 6301 aggcaagagt tcaggaaata ttttcgctgt gcaaagaaag gcttgagcaa gagggaatct 6361 taaatggttt caatggggga attgtactgg ccgggggcgg catttcatat attgacggtt 6421 ctgttcagtc tgcaaaggaa atctttggct tgcctgtcag gattgtgtct tacaaagccc 6481 tggaaataaa aaatgccgaa catgtgacgg caatggccac ggtaaagtat gttgcaaaca 6541 gaatcaagtc tgaggcaaaa ggcggcggta ctaaaaacaa caagcccggc aaacagaagc 6601 aaaaaaagga atatggtttt ctgaaaaaaa tagccagttt ttttcacgga ttattttgac 6661 atgctggtta taattttcaa atatacattt taattgattt ggaatataat tatttttaac 6721 tagttttaaa tcttatataa aattttttcg atttttaccg attaatatat caaattaaat 6781 cctgaatgta tatcttaagt ttataaatat tggatgggat acttaaaata caatcttgcg 6841 caatctccaa tattaatata ttattaaata ttgagggaat aaatgttacc caattaatga 6901 atttagaatg atatctttgt aaattggcat agaaatttta atgaaggttt ggttattacg 6961 aatgaaaaag aagggggact taagttgctg gagtttgata ttgatatgga acaatttgcc 7021 cagataagag ttgtaggtgt tggcggcgga ggaaataatg ctgttaatag aatgatagat 7081 gcaggattgc gtggagtgga atttattgca ataaatactg ataaacaggc tttgtattta 7141 tcaaaggcaa atacgaaaat tcagattgga gataagttga caaaaggtct tggagccgga 7201 gcgaatcctg aaatcgggga aaaagcggcc aatgagagca gagatgaaat tgctcaggca 7261 ataaaaggtg cggacatggt ttttgtaact gcaggcatgg gcggaggaac aggaaccgga 7321 gctgctcccg tagttgctga aattgcaaag gaaatgggaa ttctgactgt cggagtggta 7381 acaaagcctt ttatgtttga gggaagaaag agaatgcagc atgccgaaag aggtatagag 7441 aaccttaaaa acactgttga tactctggtt accataccga atgacagact gctccaggtg 7501 gctgaaaaga aaacttccat tgtagatgcc ttcaggatag cggatgatgt gttaagacag 7561 ggtgtacagg gtatatctga tcttattgct gtacccggtt tggtgaattt ggactttgca 7621 gacgttaaaa ccattatgca aaatacaggg cttgcccata tgggtattgg acgggcatcc 7681 ggcgacaaca gagctgaaga agctgcaaga caggctattc agagtcccct tttggagaca 7741 tccattgaag gagcgagagg ggttcttctt aatattaccg gcggggctga tttgggatta 7801 tttgaagtta atactgcggc agagctggtg caaaaatcgg ctgatcctga tgcgaatatt 7861 attttcggtg cggttattga tgaaaatttg aaggatgaga ttttaattac cgtaattgct 7921 acagggtttg acaaagttcc ttcaatcagg aaatctgaca agtctgctgt ggctgataaa 7981 gcgccttcgg caacttccgg cgaaaaagct tctgcaagcc agtttggggc ggatgaactc 8041 gaaataccga ctttcctcag gagaaacaga tttaaataaa cacttttcaa caataaagca 8101 caggagtata tcgaaaagga tatactcctg tgtttttttg tcataagatt tttttattct 8161 atgcttcagt tttacaaaat aaatataaat ttatctgtat aatcaataat aaaaatacat 8221 gcttttgcat atatgttatt taggacagtg ctttatgtaa ggtactgtaa gaataatttt 8281 ctctatgatt ttgccggatt cgggggtcga gggaatgaag gtatacatcg atgtgctggt 8341 aatggaaaac atcgttatga attatcttat tttactgctt actgccaagt ttatgagaca 8401 caagccgtct catttgcgtt tgtttctggg ggctttggca ggggcggcat atgtggttgt 8461 actgcttttg atgcccaatt tgaaagtata ttgcaccacg ttggctaaat ttgccttgtc 8521 cctcctgatt gttgcaatag ctttttctcc ggccaaaccg gcacttttca ttaaaacact 8581 ggcggtattt tatgtttcga cttttatatt tgcgggagcg gcatttgcat ttctttattt 8641 gaatcaaacc ggcggttttg tcaggaacgg catagtgtac atatggaatt cgaaaggaac 8701 gaccctcttt tttgctgtgg caaccgtcgg cataattata agaattttct gggacatagt 8761 acagcaaaga atttcaaaag aaaagcttct catgcctcta aagattgctt ttggaaatgg 8821 aaccatagaa ttgtttgctt tggttgatac cggtaactct ctttgcgacc cgttgaccaa 8881 ctcccctgtt gtggttgtgg agtttaatgc cataaaaaac atattaccca tggaaattca 8941 gagaattttt gatgaatcaa aggaaaatga cctggacagt gtgaccaaaa tagtgtccga 9001 ctccaagtgg atgtccagat tcagacttat accttttacc tcattgggca aagagaacgg 9061 aatgctgatt gggttcagac cggactatat tgaagtgggg gaaaatgcgg agaaaaaagg 9121 aataacggat gtaattatcg gcatttataa cagagctctg tcaaagaata ataattacag 9181 tgcactactt agcccggaac tgatttaaat tgtaactttt caacaacgaa tataaatttt 9241 ttacgaaagg ggtatataat atgttttttt taaagaagct gaaactttct ttaatggttg 9301 ggtatattaa cttacttaac aaactgaagc tttacaacaa ttatcctgtt tactacattg 9361 ggggaagtga ggctcttccg ccgccgctta ccaacgatga ggaaaattat cttttaagca 9421 agcttgagaa aagggatttt ggggtaaagt caattttgat tgaaaggaat ttaagacttg 9481 tggtttatat tgcaagaaaa tttgagaata ccggagtggg ggttgaagac cttgtttcca 9541 ttggcaccat tggacttatc aaggcaatta acacatttga ccccaataaa aatataaaac 9601 ttgccacata tgcatcaagg tgtattgaaa atgagatact tatgtacctt aggagaaaca 9661 acagaatgaa gacggaaatc tcaatagatg agccgctgaa tgtggattgg gacgggaatg 9721 aattgcttct ttcagatatt cttggaacgg aaaatgacct tatccacagg agtattgagg 9781 acgagataga caaagagctt cttgccatgg caatgaaaaa gctgtctgtc agggaaaaga 9841 agataatgga gcttcgattt ggtcttacaa acggcggagt tgaaaaaacg cagaaggaag 9901 ttgccgatat gcttggtatt tcccagtcgt acatttccag actggaaaag aagattatca 9961 gtaggcttag aaaagagata agcagaatgg tttgattgta aaaaaataca agaaaaattg 10021 aatgttagaa ttcccaatta cttcgcggtt tgtcaaggtg tttttatgaa attttgtagt 10081 ctttttagca gtataaaaat gacctccgtg gcaataatga tactgacttt aaattattgc 10141 cgggaggttt tttctatgct agtcaataaa gtagaaatat gtggtgtgaa cacatcaaag 10201 ttgccagtac ttaccaatga acaaaagaaa gagctcttcg aaagaatgca taaaggagat 10261 acctcggcaa gagaggaatt tataaaggga aatttgaggc ttgtgttaag tgttatccag 10321 agatttaaca atagagggga atatgttgac gacctttttc aggtcggatg tataggtctt 10381 ataaaggcaa ttgacaattt tgacgttact cagaatgtta agttttccac atatgctgtt 10441 cccatgataa ttggagaaat ccgaagatat ttgagggaca acaatgcgat tcgtgtaagc 10501 agatctttga gagatattgc ctataaagcg cttcaggcaa aagaaaaact tacaaatcaa 10561 aattcaaaag agcctaccat agaggaaata gccaaagaac tgggccttcc aaaggaagaa 10621 gttgtgtttg ctttggatgc aatacaggat ccgatttctc tgtttgaatc cgtgtatcat 10681 gacggtggag atgcaattta tgtgatggac caggtaaaag acgagaaaaa taatgatgaa 10741 aactggcttg aaggtatagc tttaagtgaa gctatgagaa aactcaatga ccgggaaaag 10801 cttatactga atttgcgctt ttttgacggc agaacccaga tggaagttgc tgaagaaata 10861 ggaatatcgc aggcccaggt ttcaagactt gaaaaaactg cgcttatgca tatgagaaag 10921 tatatttgat gttttgatgt atatttgtgt aatagaaaat agtttccact gattatcaat 10981 taaaggatag aatttatcaa ttaaaggata caatggggat tggaaactat atttcgataa 11041 attttgaagg agtcagggag cggaaaacat tttgatgttc tctgactcct taattaatgg 11101 gacaaaagcc actgtaacat atcatttttc gtaaaatcat atattaaacg tagagattaa 11161 aaaagcctta ttcggtggtg gtattatgaa caggacgtct gattttaggg aaaaagaagt 11221 aattaatata aaagacggaa ggagacttgg atttgtcagc gatgtggaaa taaatctcca 11281 aagcggcaga attgaggcga ttgtaattcc aagcggggga agactccttg ggctcattgg 11341 cagagacaat gaatgtgtta taccttggga aaaaataaaa aagatagggg aagatattat 11401 tctggtggaa atggatgaca gatttatacg aaaacatttt gaatgagtgc tgaatcaata 11461 acggtattta ttaaaaacat tttatagtgt attatataaa aagatatgta tttttacata 11521 gcaaaagata gtatttgatg gaaatggatt tgcataaaaa gtatttcaaa aaaacagtcg 11581 gaggaggtat gaaatgaagt gcccatattg cggttatatt gaggataggg ttatcgattc 11641 aaggccaacg gatgaggggt cggcaatacg gagaagaaga gaatgttcca aatgcctgaa 11701 aagatttacc acctatgaaa aggttgaaag tcttcccatt atggtcataa aaaaagacaa 11761 gagcagacag gcttttgacc gggagaagct tttaaacgga attttgaggg catgtgaaaa 11821 aaggcctgta tccattgaac aactggaaaa actggttgat gacattgaga gtcaaattca 11881 taattccctg cagagggagg ttacttccaa agatatcgga gaaatggtaa tggcaaagct 11941 caaaaacttg gatgaagtgg cttatgttag gtttgcgtcg gtttacaggc agtttaagga 12001 tataaatacc tttatggacg agcttcgcaa gcttttaaac gagaagtagg aacattggga 12061 agcaagcagg agttaattta caaaagagga aagagtgatt aaccgtgaat gaagtattgg 12121 ctaaaaatct gtccctttta aaagagtatc agcctgaaac atacctgaag cttgacagat 12181 acataaaggg agagtatgtt ccaaaggaca attcagtgga aaaaatactt ttggcccgtc 12241 aggacgatct cataataaat attttggtaa aatgctctga caaagatttt ctgctttgtg 12301 accatgaaaa cccgattaat gaagcttatg cctggattga caaatatatt gacccttcca 12361 acaaggcgga cattgtcttt ggaatgggat tggcatttca ccttgaagtt cttcttacaa 12421 gttttcctaa caaaaaagta attgtaattg aacccaatat aaacttgttt tatcagattg 12481 cctgtataag aaatcttgag ccggtgatta aaaaggctga aataattgtg gatgaagact 12541 tggatgttat acttgagaga ataaattcct tgttctggga tacggaaaag ggcgggattc 12601 aggtacagcc tcttgaggtg tatggtgaaa tgtttcccga aatgtgggac aagcttcggg 12661 acagtttcat aaagcttgca aacaatttca ctgtcgatat tgcaaccaga aggaaatttg 12721 gagagctgtg ggtgcacaat aatataaaaa atctcaacaa aatttgtgaa gcctccaatg 12781 ccggtgttct ggtcggaaaa ttcaagggca ttcccggtat attggtatcg gccgggcctt 12841 cccttgaaaa aaacatccac cttttaaaag gtcttgagga taagtgtgtg attatggcag 12901 cgggaacggc agtacgaatt atggaggatt tcggtctggc accgcatttt atggtgggaa 12961 ttgacgcggg agctaaagaa ggggaaatac attccaacgt aaaaaacaaa gatatatatt 13021 ttatttattc aaaccaggtt tcaacatatt ctgtggatgg ctacaaaggc cccaaatttg 13081 ttatgaatta tcctattgac atgtatacgg caggcttttt tgagtatgcc ggtatcaagt 13141 cggatttttt cctaagcggg ccctcggttg ccaatacctg ctttgacatc ttgtttaaga 13201 tgggctgcga cccgattata attatcggtc aggacatggc gtttacatac ggaagcatgt 13261 atgcaggtga ggtgccggga acggttgtag acggtgccgg ggaagcaaaa agaaggggat 13321 atgttcttgc aaaagatatt tacggaaatg aagtttatac cacccggcca tttcttgcaa 13381 tgagaaactg gtttgaagga tattttgaaa aagtgcggga caaaacgaca ataataaatg 13441 ccaccgaagg aggactgaat atttcgtatg ccagaaatga aactcttgag gccgcactaa 13501 agagctgtaa tttatcagaa tcaggcatta aagatcatat caggtcgctg catgaggaag 13561 gaaaatttgc ggatacggta gcttcaaaaa tcgaggaata cagagcatac gttcaaaggg 13621 agataagacg gctggaacag ctttccaaaa ggcagcttga gacagcagag gatttaaaga 13681 gagatgttta tcatccgtca aaaagccgct caaggtttat taaggctgtc aattcaataa 13741 atgaaatgtc ggacagggtt cttcaatctc cgatatacaa ttcccttctt aaaaatcttg 13801 ttgaaattga cttttatatt ataaaagcgg aagtggacag gttagtaaag atattaacaa 13861 aatatgacga tataaagaat gtatatgtga atgccatatt gagtcagaat caaaaactca 13921 acgcaagcct tggcaaaatc aagaaattct ttgacgaatc ggatgttact gcttaattaa 13981 ggcggcatgt tacaatgact tgatttgtac aacatggtat aattatctga aaatacacaa 14041 taaatgaacg gggtgcatat gatgaaaaaa tggctgtgta ttttggtgat agtcgttttg 14101 gcaagtacat gtcttattgc ttatgctgct gaggcaaacc agtggacggc gttgagggca 14161 acgttcaagg tttttgtaaa aggtgaggag tttaagtccc aggatccgat agttgccatc 14221 aacggaagga cctatttacc gcttaaagca ataggtgacg tgctgggagt ggatgtggtc 14281 tggaatgaag gattgagacg tgtggaagtg gcaatgtcgg aaaatcagaa cggcgataag 14341 ccggatgttg cgccggttgt ggcaattcat gaagctgaaa ctgcggacta tatactggat 14401 gtgctggttg aaggggtaaa ggcaaaagcc ggtgatacag tggagatacc tttaaaattt 14461 gaaaacgtac cgtcccatgg aatacagtcc tttaacctga gtttgtatta tgacagcaaa 14521 gccatagaag ttttaaaagt ggaaccggga agcataatta cggatccggc gaacaatttt 14581 gattacaaca tcgtttacaa ggattctgaa atagtctttc tctttgatga tgacaagcaa 14641 aagggtgaag ggctgataaa gactgacggt gtttttgcaa aattgactgt aagaataaaa 14701 cctgacattt tcaaagacag cggagcaact aaaaaatata gtttaattac ttttggagaa 14761 agcaatttct gtgattttga tttgaaacct attcttgcag tgcttaaaga aggtaaagtg 14821 gaaattgaaa aataatttat aaacacatat acaaaaaaag taagggagac ttaaaaggtc 14881 tctcttttta tttggctaat ctcccgaggc tttacggctt ttatttttgt aacacattag 14941 ctgtggttaa cataagatat agaaggatga ctgtgcattc aaggagagag attgatgtca 15001 agagttggag gattgtcagc aaaaagcatt tctcaattac tgtcaaacta tattggtgaa 15061 actgttacta tatttacaaa aagcggcgga cagtcgggag caggttttac cggagtgatt 15121 ctttctgtca atgactgttt tgtgagactg ataacaagaa ttggtccgcc tccgggatgt 15181 gccttgggta atgcctgtac gggatttgac gttggaaata agtacggaaa aggcattgcg 15241 ccttcgggtg gtggatgcgg tataagcggt ggttatgccg caggatatgg aaaaggatac 15301 ggaccgatac ttcccgccaa tgaaaacggt gcaataaccg ccggtggttg gaatggttat 15361 cctgtatata ccgtcggttc ggtggctgac atacctgtag acagcatagt agcctttgtc 15421 cataatgcgg tctgatggac gccggctttg aatttgacat ttgggaacgc aaaatccgca 15481 aataaatatg tgattttgat tcagacaagg ttatgtacaa aggaagtaat tttgtccaca 15541 ggaattatgg cgagtgatcc cagagggctg aaatgagaat aagactgtcc caaaccgtat 15601 gaacagacag gatataaaat acagggattg ttcagggagc atgccggggg cagagctatg 15661 gaaataagaa gctcaatgta cacttcattt acaaataaaa gtatgcctgt aaagcctgcc 15721 ccggaaattc ctcccgattc aacgaatacg gttacggttt cgcctatgta atttgccata 15781 tgggctgaaa agcaggtatt atcgaataaa aaagactttg catcgaaaat tgttttacag 15841 tcaggctttt gcctgatttt ttctatttcc gtctgttttc ttcttcgcct tctcaggaaa 15901 aacatcaaac attcctcctt acacataatt ttaggagaat acggctatga tgcagtttgt 15961 gacgataagg taatacattt tgagtttcta taatatatca tagccttaaa ttgtaaaaat 16021 ggttactgtt gtagagtata ggagataaaa caacagaatt tttatataaa tggtttttat 16081 atagacaatt tagtgttgta aatttgcaaa atcactgcta taaattaaaa aataaataaa 16141 acagattttt aaaaaagatg tagaatttgt acaggttgtg gtataattat gtggcgatat 16201 ttggataaag ttttgaaagg ttgggggaag gatgctctca aaaataaaaa cgatgggctt 16261 gatgggtata gatgggtatg tcgtgatggt ggaaacggac ataagcaacg gaatcccgtc 16321 atttgacatg gtggggcttg gagatactgc tgtaaaggaa tcaaaagaac gggtgcgcgc 16381 ggctataaaa aatgccggtt ttgagtttcc gataaagagg attactgtaa atctcgcacc 16441 tgcagacaag aaaaaagaag gttctgcttt tgacctgcca atagccctgg gggtattgac 16501 agcaacggaa cagataaata acaaaaatct tgacaggtat gcttttgtag gagagctttc 16561 cctggacgga gaaataaaac ctgtaagggg cattcttccc atggtcttaa gtgtaaggga 16621 caacggtgtg gaaaacatag tcctgcccat tgaaaatgcg gatgaggcag cggttgtaaa 16681 agatattaat gtgcttccgg caaagaatat aagggatgtg gtaaatcatt taaacggagc 16741 actggaaatt aagaagcatg aagttgacat tcaatccatt tttaacggaa gtcttgattt 16801 tgatgtggat tttgctgatg taaaggggca ggaaaatgta aaaagagctc tcgaagttgc 16861 ggccagcggg ggacacaact gcctcatgat aggctctccc ggaagcggaa agacaatgat 16921 tgccaggagg cttccgacaa ttcttccttt aatgacgttt gaagaagctc tggaagtaac 16981 aaaaattcac agtattgccg gcactttgcc cgcaaatact tctcttatca cccaaagacc 17041 tttcagagcc ccgcaccata cgatatcaaa cgtcagcctg atcggaggag gaaaaatacc 17101 aaagcccggc gaaatgagtc ttgcccatta cggtgtgctg tttttggatg agctgccgga 17161 attcaataag gatgcattgg aggtgttaag gcagcctctt gaggacggtg tggtgactat 17221 ttcaagaatt aacgccacat taacctatcc tgcaagaact acattgattt gtgccgccaa 17281 tccgtgcaaa tgcggcaatt accttgacaa tacaaaagaa tgcacatgta cgccaaaaca 17341 gattcagcag tatttaggaa aaatctcggg ccctcttttg gaccgaattg atatacacat 17401 agaagttgca tcggtaaaat acaatgactt agaaaacgag gaggaagggg aaaagtcaag 17461 cgttataagg gaaagggtga acagaacgag aaaaatacag caggaaagat acaaaggact 17521 tggcattttt tccaacgcgg agcttacacc ggcgttaatc aggagattct gcaaactgga 17581 tgacaagtgc aaagaaattt tgcgaaatgc atttgaaaag cttggattaa gcgcaagggc 17641 gcataacagg atactcaaag ttgcccgtac tatagccgat atggaggaaa gtgagagtat 17701 aaaagcgaat catttgttgg aggctataca gtacagaagt cttgacagaa aaaaatattt 17761 gaatatttag aacaggagga aacaaaatga aatcttacag aaaggaactt gtatttaata 17821 ttccgtcaag gagggcatat gtgaatatta cgccccaggt gcaggagtgt attgatgaaa 17881 gcggtataaa agaaggactt gtattggtta atgccatgca tattaccgca agtgtttttg 17941 taaatgacga tgagcctggg cttcatcaag actttgaaaa atggcttgaa accttggcac 18001 cggaaaaacc gtacagtcag tataagcaca acggatacga agacaatgcc gacgcccatc 18061 tgaaacgcca aataatggga cgtgaagtgg tggcggccat taccaacgga aaactggatt 18121 ttgggccgtg ggaacagata ttttacggag agtttgacgg taaacggccg aaaagagttt 18181 tggtgaaaat aattggtgaa taagcaaagt taaatggatg ggggttaaaa cagtgaggat 18241 tattggaaat attatatggc tgttgtttgg aggaattgtt ttggctttgg gctggatgct 18301 cgcagggttg attttatgca taacgattat tggaatacct ttcggtgttc aatgctttaa 18361 aattggtgcg cttgtgttat ggcctttcgg cagggaagtg cagattggaa attttggagt 18421 cggtggattg cttctcaata tcatctggat tatctttttc ggatgggaac ttgctttatc 18481 ccattttatt acgggattgc tgttttgcat aacaattgtc ggaataccct tcggccttca 18541 gcatttcaag cttgcgaaac ttggacttgt gccttttgga gcaagaataa attaaaacaa 18601 atcagtttta atgatataat tgcataaaac gtggtatttg taatataccg gatgcttaat 18661 tggagaatat gattgattga caagttgttg gtgtaaagat tactatattt atattatcat 18721 tgaaatgaat gttattgaaa tggatgttta tattgaaaaa ggcttatttg ttgaaaagta 18781 ctgcttttga ggagaaaggt catgacgaaa ttaatatcat ggaatgtcaa tggtctgagg 18841 gcctgtataa acaagggatt tttagattat ttcaaaaaag ccgatgcaga tatattttgc 18901 atacaggaaa gcaaggttca gcccgggcaa attgagcttg aacttgacgg gtatcatcaa 18961 tactggaatt atgctgagag gaaaggatat tccggtactg cggtgtttac ccgtataaag 19021 cctctttgtg ttcagaatgg tattggaatt gacgaacatg acagggaagg cagggtaata 19081 accctggaat ttgacaatta ttatttggtc aacgtgtata ctcccaacgc gaagaaagag 19141 ctggaaaggc ttgattacag aatgaaatgg gaggatgact tcagaaatta tcttgtcggg 19201 cttaaggcca aaaagccggt gattgtctgt ggagacatga atgtggccca taaggagatt 19261 gaccttaaga atccggaatc caacagaaga agcgccggtt ttaccgatga agagcgcgca 19321 aaatttacgg agcttcttaa tgctggtttt attgatactt tcagattttt ctatcctgat 19381 aaaacgggtg cgtatacatg gtggtcatac atgtttaatg cccgtgccag gaatgcaggg 19441 tggagaattg attatttttg tgtgtcggag gaactaaaag accgtcttgt aagtgcctcc 19501 atacatgatg atgtgatggg ctcggaccat tgtccggtag agcttcaaat aaaatagcga 19561 caatcagaaa tgttgcagct gggacattgc caatgattgt atccggaaaa ccttgattca 19621 gtgaacaata cgtgataaat tattttgtga aaatgtgagt agtgccgctt aaaatttgaa 19681 aaatcatttg gtttgcctat ggcatcactt aagctcgttt atgaagggga atattaatgg 19741 aaagtaattt gaaagagtgg gtatggctaa gttccattcc cggaattgga gcagtcaagt 19801 ccagaaaact tctggagcat tttggggata tacataatgt ttggagtgcc actgcggctg 19861 aattggctgt gcttcctttt ttaaacagga aagatatttt aaatttaacc aatgtaaaat 19921 tcaagcaaga cgttgagcgg catcttgaaa atatccacaa aaatgatatc aaggttatta 19981 cattggaaga tgaattgtat cctgcgtacc ttaaaaacat atatgatcct cctttggttc 20041 tttatatgaa gggaaccatt caagaggagg aaaaatatct ggctgtggtt ggttcaagaa 20101 gagcgacgtc ctatggactg gatatggcga agaaaatatc ccgagagctt gctgaatgcg 20161 gtattaccgt tgtaagcggc atggcgaggg gagttgattc ttttgcccat atgggagctc 20221 ttgaagtaaa aggaaggacc atagccgttt tagggtgcgg tcttgatata gtatatccat 20281 acgaaaataa aaaacttatg gaaaatataa ttgaaagcgg tgcctgcctg tccgagtacc 20341 ttccgggtac tacgccggtg ccgggcaatt ttcccgcgcg caacaggatt atcagtggta 20401 tttcactggg agttgttgta atagaggcgg gagagcgcag cggttccttg attacggcaa 20461 attttgcttt ggagcaggga agagaagttt ttgcgcttcc gggaaatgtc aacagtatta 20521 aaagtaccgg aaccaataaa ttaataaaag aaggggcaaa aatagtaaca ggaattgacg 20581 atatattaga agaattaaat atttatttca tcgaagaaaa tacaaaagtc tcctttaaca 20641 aaaatcttca ggatgaaaga attttaagag gccttgacaa tgatgaaaag aaagttgtgg 20701 aatgtttgaa acttgagtca atgcatattg acaatattgc aagaaaaacc ggatttggca 20761 tacagcttgt taattcaata cttgtaatgc tcgaattaaa gggagttgtt gagcagcttc 20821 caggaaagat attcaagtta aagttgtaag taataaataa taattgaaat atgacaatat 20881 tataataaat attataatat actattaaaa aaataacaga taaatataac tggaggaaaa 20941 agatggctga caaattgatt attgttgagt ctcccgcaaa ggcacatact attgggaaat 21001 tcttgggaaa agactataag atagttgctt ctgtcggaca tgtgagagac cttcccaaaa 21061 gtcagatggg ggtcgatata gagaatgatt ttactcccaa gtacattaca ataagaggta 21121 agggtgaaat aatttcaaaa cttaaaaaag aagcaaagaa cgcaagcact atctatcttg 21181 caaccgaccc tgaccgtgag ggtgaggcta tttcgtggca tttggctact ttgcttaaca 21241 tagataaaaa tgagaaatgc aggataactt ttaatgagat aaccaaaaat gctgttaaaa 21301 acgccataaa atcacccagg gaaatcaaca tggacctggt tgatgcccaa caggcaagaa 21361 gggtattgga caggattgtg ggatacaaga taagtcccct gctttggaaa aaagttaaaa 21421 aaggattgag tgcaggaagg gttcagtcgg ttgcgacaag gcttatctgc gacagggaag 21481 aagaaattga aaagtttgta cctgaggaat actggaccat aactgcaaaa ctcttaaaag 21541 gtggagtaaa ggctcctttt gaggccaaat tttacggtct ggacaataaa aagactgaac 21601 ttaaaagcga ggaagaagta aataaagttc tggatgagat aaaagacgcc gtgtttgtgg 21661 ttcagaaagt gaaaaaaggg gagaaaaaga aaaatcctaa cgcaccgttt accaccagta 21721 cgatgcagca ggaagcttcc aggaaactgg gattttccac aaaaaagaca atgatggtgg 21781 cacagcagct ctatgaagga attgaagtaa aaggtgtcgg ggctgtgggt cttgtcactt 21841 atattcgtac cgattccacg agaatttccg aggaggcgca aaatcaagct gcaaagtata 21901 ttaaagaaaa gtttggtgaa agttatcttc ccaaagaaaa aaatgtttat aaaaacaaat 21961 ctgcctctca ggatgcccat gagtgtataa gaccgacatc ggttgaaatg gatcctgagt 22021 ctgttaagga ttcacttacc aaggagcagt accgtctgta taagcttata tgggataggt 22081 tcgtggccag tcagatggcg ccggccgtat acgacactat aaatgcggat attgaagccg 22141 gaaaatatct tttcaaggca agcggctcca ctgtaaagtt tcctggattt acggtcctgt 22201 atcaggaaga caaggacgat gaaacggaag aaggagaggt cattgttccg gagcttgcgg 22261 aaggggaaag cttaaagctt aaaaagcttg aacccagaca acatttcacc cagccgccgc 22321 caaggtatac ggaagcaagc ctggttaagg ctttggaaga aaaaggcata ggaagaccga 22381 gtacttacgc ccccatcatt acaaccattt tggcccgggg ttatgtggtg aaggaaggca 22441 agacattggt tccgaccgag ctcgggaaaa tcgttacgga tattatgaaa aactattttc 22501 aggatatcgt ggatgtagag tttacggctc aaatggagaa aacgcttgat gaagtggaag 22561 agggcgaaaa aagatgggta gatgtcatga gaagctttta ctcccaattt gttgatgttc 22621 tgaaaaatgc ggaggaaaag ataggcaata ttgaagttcc cgaggaagta accgatgaga 22681 tttgtgaaaa gtgcggaaga aacatggtaa ttaaagttgg aaagaaagga agatttttgg 22741 cgtgtcccgg ttttccggag tgcagaaacg ccaagcctat tttggaggat gcgggtgtaa 22801 cctgtcctaa atgcggcggt aaagtgtaca ttaaaaagac gcggaaaggc aggaaatatc 22861 ttggttgtga gaataacaac agcgatccca aatgcgattt tatgacttgg gatatgccgt 22921 caaaagaaaa ctgcccgaaa tgcggaagtt ttttgcttaa aaagtattcc ggcaggaagg 22981 tacagctaaa atgcagcaat gaaaactgtg attatgtaaa aacggggaaa gaaaaaaagg 23041 aagatgaata atatgatcga ttatataaat gtgataggcg ccggacttgc cggctgtgag 23101 gcggcatggc agattgccaa aagaggaata aaagttaagc tttttgaaat gaaaccgaaa 23161 aaattttcac cggcacatca tatggaaact ttcgcagagc ttgtttgcag caattccttg 23221 cgttcaaacc agctggaaaa tgcagtcgga ctcttaaaag aggaaatgag acttttgaac 23281 tccataatta tgaaatgtgc cgatgctgcc caggttcctg ccggaggagc tctggcagtg 23341 gacagaacaa agttttctca aatggtgacg gagcttataa aacaaaatga aaatatagaa 23401 gtgataaatg aagaggtacg ggagctgccg aaggaaggaa ttacaattgt tgccacaggg 23461 cctcttacat ccggggatct gtcaaaacat ttggcggatt ttgtaggtga aggctatctt 23521 catttcttcg atgctgcggc tcctattgtt actttcgagt caatagacat gaacaaggca 23581 tttaaggccg cacgttatgg aaggggaacg gatgattaca taaactgtcc catgaacaaa 23641 gaagagtacg agattttctg gaatgaactg gtgaatgcag aacttgcgga agtaaaggac 23701 tttgaccgcg aagtggtttt tgaagggtgt atgcctgttg aaaccatggc caaaagagga 23761 aaggatactc taaggttcgg tcctttaaaa ccggtaggtc ttgttgaccc caataccgga 23821 aaggaacctt atgcggttgt tcagttaaga caggacaaca gtgagggaac catgtataat 23881 atggtaggtt ttcaaacaag gcttaagtgg ccggagcaaa aaagagtgtt tcgattaata 23941 ccgggacttg aaaatgctga atttgtaagg tatggtgtaa tgcacagaaa tactttcata 24001 aattcgccgg tacttttgga tgccacatac tgccttaaaa aatctcccaa tatttatttt 24061 gcggggcaga ttaccggagt tgaaggatat gtggaatcag cctcttcagg catggttgcg 24121 ggaattaatg ctgccatgga ttttctggga aaggataggg ttgtatttcc gaaaagtaca 24181 gccatcggtg ctttgagtca ttatgtttcc gacagcagta taaaaaattt tcagcccatg 24241 aatgttaatt ttggcataat ggagagcttt cctctcaaaa tacgggataa aagaaaaaga 24301 aattatgaga cggcaatgcg ggctcttaag attttaaaag agtatgtttc aaagtattcg 24361 taaataaata aacaaggctt tttgaatata aattttttaa ttatagaatg attgttgttt 24421 tatttttgtt taaattatga aaaaatataa aattattatc ataattttgt gcaaaaacag 24481 ttgtattttt tcacaagttg tgataatatc atttataagt aatggtattt tatgtattag 24541 ccagatttca tgcagttctt ttttgatttt tttcacttgt ctttaaaaag tcgggagtat 24601 tatttgtact ttttggttta atttttccat aaaagactga gaaaagtaaa tagaggtata 24661 ttcctgtgcg agtgtcaagg ttaataatac cattgcaact caaaaaaata atgcaggaaa 24721 atatgtttat ttgtcgaaat atattgagaa gcattacatt cttaattgat ggcaaagtca 24781 aaatacacag gaggtgtatc caatgctggg cagaattctt gcaggaaccg atgtgcttga 24841 aaaatcgttg gatgcagcat tgctacggaa tgaagctatt tcacagaaca tagcgaatgt 24901 cgacactccg ggttataaaa gaaagacggt tgctttcgag gaatatttga atgatgcaag 24961 agcaaaaatt aaaggtataa ggacgaggcc tgaacacatc ccggtgggtg ccagagacgt 25021 gatggacatt gatataaagg tttctgagga tagaagttca ctttcaatga gacttgatga 25081 aaataatgtc gatattgaag aagaaatggc ccagatggct aaaaacacca tcaaatatta 25141 tctgcttacg cagaaaatca gcggtgactt caataaaatc aagtccgtta ttaaagaagg 25201 gagataataa atcatgggat acttcacttc tcttgatata agcgcatctg ctcttacagc 25261 ccaaaggttg agaatggata caatttcaca gaatattgcg aatgcaaata ccacaagaac 25321 tgaaaacgga cagccctata gaagaaaaac ggtgctgttt gaagaaaaat cttcaaccgg 25381 ttcattttcc gaatatctag aaaacagcat cagaggaaaa actgcgggag cgggagtcag 25441 agtaacggga atagtggaag acagatctcc ttttaaaaga gtgtatgatc ccggacatcc 25501 ggatgcggac gaggaaggat atgttttaat gccaaatgtt gacgtaatta cggaaatggt 25561 gaatatgatt tcggcaacga gggcgtatga ggcaaatata acagctataa acactacaaa 25621 aggtttggca atgaaggcgc tggagatcgg aaggtaatcc gacggtctgt ctttaaatat 25681 gaaaaattca atgacgttgt tcaaggagga tatttatggc tgtaaacggt attaatttag 25741 taactccttc ggtatcagga attgatttta cggtagggaa tacgataagt aataaaaatg 25801 aaaatgttgt tcagtctttc agtgattatt tgaaaaacgc cataaaacag gtggatgagc 25861 ttgaaaaaca gtcaaaggct gttgcggagg attttgcggc aggcaaaacc gacaatatcc 25921 atgaggttat gattgccgcc caaaaggcag atatagctat tcaatttaca ttgcaaatca 25981 ggaacaaaat tttggatgct tataatgaaa taatgagaat gcagatctaa ttggttgcat 26041 gttttacata tcacttcttt actgggtgca tagatctcac gaaagatgat aaccgttgac 26101 taaggtggtg gattcatgcc tgaggtacta tcaaaaatgc agcagcaggt cacagatttc 26161 tggaaaaacc tggacaagtc ccaaaaaacg aggattcttg tgacttccgg tattttggta 26221 gttgtactta caatagccat agtaatgctt acaaggacta catatgttcc tttgattaca 26281 gttgaagatc ctgatagcat ttctgctatt gaggaggctc tgaaggaaag aaacataaaa 26341 tataagcacg gcgagggaag gcgtattctt gtcgactcaa aggacaagaa tgaggctgaa 26401 tttgctcttg catccgcagg attgactgag ccgggaatga catttgagga tgcatggagc 26461 cttcttaaag taagttcttc tgagagtgac aaaaagcagt tgtggcagaa tttcaagaaa 26521 aacagtctta ttgcgaaact taaaatgttt gacaatgtaa aagacgccga cattgagctt 26581 acaataccgg aagataccat gtttttcacc gattcaaaga gtgaagccaa agcagctgtc 26641 agaataactc ccaagggaga attaactccc gagcaggttg aaggaatagt tatggtagtt 26701 gcctcgtcta tagaaggact ggatcctaaa aacgtaacgg ttgtagacaa taactttaat 26761 atattgaatc aggatttgtc agacggcatg aatataccct cgagccatta caagcttaaa 26821 cttcgtataa aggaagagct tgaaaagaat ataaaaaacc tgtattccgg tcgttcggac 26881 agctatgact ttataagtgt tgccgtaaat ccggttttgg atctggacaa agttacaaag 26941 aacagaaaag aaattgaaaa gcctaccgga ttggatgagg ctgtagtcag tgaggaaaga 27001 aaaaccgaag agctgataaa cggaaatcaa ggcggcgctc cgggaatgga tgcaaatccg 27061 ggaaccgggg atgttccgac ttatcctata gatgcaggac aaaactcttc ttatgaaagc 27121 aaatcggaga taataaacag aatatttacc gagacattga cagcggaaga aaaagccata 27181 gggacaatga attttcaaga atcctcaatg acggttgccc tgtggtatgg gaatagagtg 27241 cctgatgaca gcaaactgac agatgaattt atagaagagt ttaaacaggg gttgagcaat 27301 gctacaggaa ttcctgttgg aaaaataact gttaacaagc agaaattggc acctcaggag 27361 gaagagatag tgccaatgtc cgaaaggata aaacaattta tagatgatta tggtttcttt 27421 gcactgttga ttatattgat aattgcgtta atgctttcag taatgccgag gaagaaaaaa 27481 tcaccgcagc tggcgcctga acttgcaacg gcgggaggtc ctaatgttga tgaagctgaa 27541 gaagaattgc ctcctataaa ctttgaagaa cactctgaaa tcaagaaaca gattgaaaac 27601 tttgtaaaac aaaagccgga gtcagttgcg cagcttctta gaaattggtt gtccgaagac 27661 tgggattaat tgattttggc agtttattac aaaagaacaa caggtgtagg gggtattatt 27721 gtggctcgag gtggctccac aaaatcagaa ctgtccggaa aagaaaaagc agcaatgttg 27781 ttaattgctc ttgggcctga aagatcggca gaaatcttca agcacttgaa ggaagatgaa 27841 attgagcagt tgactcttga aattgcaaat atcagaaccg taagtcctga ggacaaggaa 27901 agagttttgg aagaatttta tcagatatgt cttgcacaga actacattgc cgagggtgga 27961 ataaattatg caaaagagat actcgagaaa gctttgggta ctcaaaaggc actggatgtt 28021 ttaaacaagc tgacagtgtc gctgcaagtc agaccgtttg actttgtaag gaaggcagat 28081 ccgtcgcagc ttataaactt tattcaaaac gagcatcctc agacgatagc gttgattctg 28141 tcgtatttga agcctcagca ggcttcaatt gtcctgtctg cacttcccca ggacaaacag 28201 gctgatgttg caagaagaat agcaacgatg gaccgaacat ctcccgaagt aataaaagag 28261 gttgaaagag tgctggagaa aaagctttcc gcgattgtta ccgaagactt taccgctgcc 28321 ggtggtgtgc aggcgatagt tgatattttg aataacgttg acagaggaac cgaaaaatac 28381 attatggaaa ctttggaagt tgaagatacc gatctggcag aagagataaa gaaaagaatg 28441 tttgtattcg aagatatact tactctggac aatcgctcca ttcaaagatt cctgcgtgaa 28501 gttgacaaca atcagctggc cattgccctt aaaggaacca atgacgaagt taagaacaag 28561 atttttgcca atatgtccaa acgtatggct gaaatggtca aagaggacat ggaattcatg 28621 ggtcctgtaa ggcttaagga tgttgaagag gctcagcaga agattgtaaa tgtcataaga 28681 aaacttgaag acgccggaga gatagtaatc tcaagaggtg ggggagatga tatagttgta 28741 tagcaacaaa gtttttaaaa gcagtcagat taatatcgga attcccgttc agatcaaagt 28801 tcctattact ccagctaatt atcagaatgt taaaaaagtt aaagagcctg aaattgactt 28861 tgattcctgt ataaatgaaa agtccgagct cctcagtaaa aaagttgaaa atgaaaagga 28921 tgttttggag aaagcccgaa agcaggcaga tgaaataatc aggcaagccg agcttgaggc 28981 ggctaaaata ttggaggaag ccaaggaaaa gggacttttg ttgatggcgg aaatagagga 29041 agacagcagg caaaagggat ttgaaaaggg atatgaagaa gccaaaagcc agtatgagga 29101 tttgattcag gaggctgagc taatcaggga aaatgcatta aaggaatacc aggagacact 29161 tcaaagtatt gaaaaagatg cgttaaatat tattttagat atttccagaa aagttatcgg 29221 cacagaaatc agcatgaaca aagaaaaact tctggaaatg attgcacagg cttttgaacg 29281 gtgttcaaac agggaaaaca taacgctgaa agtttcttcg gcggattatg attttataat 29341 tgaaaacaaa gacagaattc tttcaatggt ggaaggtata gggcaacttg aaatcgtaaa 29401 ggatcaagct ttaaagcttg gtgcactgat tcttgaaaca ccctatggaa gtgtggatgc 29461 aggaatggat acaaaactta aaaagattga agaggcattt ttcaaggtat tggcaagtcg 29521 aaaataattt cacatttcta ataaataaag aatccgggat gggaaagctt tatggcgacc 29581 attgattttt caaaatatta tgatgtcttg gataacaggg actttatcga gtataccgga 29641 aaggtttcca aagttgtggg acttacaatc gaatccaacg gtcccgaggt taacattggt 29701 gaaatctgca agataaacgc cttaagggaa aacaaggtta tatctgcgga agcagtgggg 29761 tttcgggaca ataaagtgtt acttatgcct ttaggtgaca tgaacggaat aggtcccgga 29821 agcaaagtgg tggcaaccag ggattatctg tccgttggtg tcggcaatgc acttatagga 29881 agagtaattg acggaatggg aaggcccatt gacggcaaag gtgagattgt taccgagact 29941 acatatcccg ttgaaaataa acctccgcat cctttaaaaa ggaacagaat caaggaacca 30001 ttgcctttgg gagtgaagac tatagacggt cttttgactg tgggcaaggg acaaagagta 30061 ggtatttttg cgggaagcgg cgtgggaaag agtactttaa tcggaatgat tgcccgaaat 30121 acaaaggctg atgtcaacgt aatcgccctt attggtgaaa gaggtaggga agtaagagaa 30181 tttattgaaa aagacctgaa agaggaagga ttgaaaagat ctgttgtggt ggttgcaact 30241 tccgaccagc ctgcacttat cagacttaaa ggcgcgctta tggcaacggc catagcagag 30301 tatttcagag atcagggaaa agacgtactt ttgcttatgg attctcttac gaggtttgcc 30361 atggcccaga gggaaattgg gctgtcaatt ggcgaaccac cggtttcaag aggttacacc 30421 ccttcagtgt tttcgataat gccaaagctg ctggaacggg ccggaaattc tcaatcaggg 30481 tcgattaccg gactgtatac ggtgttggtt gacggtgacg acctgactga acccgtgacc 30541 gatactgcca ggggaattct tgacggacat attgttttgt ccagaaacct ggcaaataaa 30601 aaccagtacc ctgccattga cgttctggcg agtgtgagca gggttatgcc ggatatagtg 30661 gacgatgaac atcaaaagat tgcaaacgat atcaaaaaga ccatggcgat atacagagaa 30721 gctgaggatt tgattaatgt cggtgcttat gcaaaaggaa gcaatgaaaa aattgactat 30781 gccattgagg taattgacaa gatacaagaa tttattaaac agggtgtcca tgaacgatac 30841 tcttatgaag agactataaa tctgatgaaa aatgttttga tttgacagtg tgggtaagca 30901 gggcaggtga taattgtggg aaaatttgtt tttagaatgc agtctctgct gaacctgaaa 30961 attcaaatgg aaaacagcct taaaaatgaa ctgggaaaag cggtccggga attggaaagg 31021 caaaaggata tattaaacag gctcaataga gaaatgaatg aatgtatcga aaacataaac 31081 ggtaaatttg gtgaaggaat atcggtggga gagcttcgca aatacaatac ctacatatct 31141 tatcttagtg acagggtaaa gcttcaaaaa gaaaatatta agaaagcgca attagttgtc 31201 gataaatata gagataagct gattaaagcc atgcaggagc gaaaagtgct tgaaaagcta 31261 agggaaaaaa agtatgaaga gtatgtaaga gagcagctta aggaagaaca aaagctcaac 31321 gacgaaattg taagctttaa cataagcaat tcggaagaag agtaaaactt ccaaaaaata 31381 tattttaaat aataaataca ataaataatg ctgttgggag agagacatgg caaaagaaaa 31441 gataaaagaa actgttaaaa accctgaagc gcaaggaagc ggaactgaaa aaaagaaagc 31501 tgaaaaaaat ggttttctgt ttgggctgct tgtgctgttg ataacactga ttgtcatagt 31561 cagtgttgtc ggaggggttt ttttcattgt cattaaaaac aatgtaaacg ggctggcgga 31621 aaaatacaga aacaacctga aaaatattcc tgttttaaga atggctttgc ctcctccgcc 31681 ggcggattac gaccctcttg atccaaaaaa tctcaaattg gatgagctta tcgaaaagta 31741 caaccagttc cggaaagaaa acggcgagct tgcaaagaaa cttgaggaaa ctgaaaaagc 31801 tttaaatgag cttcagagct ctcaagctga tattgaggcg ttgaggaagg aaaatgatca 31861 gataaaagcg gaaatggaag ctcaaaaaac aagatataaa gaggaactga aaaaagcaga 31921 ggagcttttg gtacaagctg ataaagaagg atttaaggaa ttttatgaaa agatgaacga 31981 gaaactggca cagagccttt atgaagagat actcaaggaa gagaaagcca atgaaaaggc 32041 gaaggaattt gcccagatat acgaaaaaat ggacaccaag gctgctgcaa aaatatttga 32101 agaactgggc gattcgcaat tggacttggt tgttgagacg ctgagaaaca tgaagaaaga 32161 tgtggctgcc gaaattatat cggaaatgag ccaaagctat gcggcaaaag ttaccgagaa 32221 gctttcaaaa gtgtatggaa ttgagtttga aaaataaaaa gttttcaaga tatttggaca 32281 atttcgaaag gaggtgaaaa aatgataact caacatttaa ttcccgattt tattgcaaaa 32341 atgaccggtt ctaccgaagt gcaaaagtcg gcgggcatga aaaaaagctc ttcatcgcag 32401 tttaaagata cccttgacct ggctgtcgaa aagtcgtatg catggcagag cggcactaaa 32461 tcctatgaat atgcaatgga tatcaaagac aggccttatc agcgtttgca aaacaaaaac 32521 atactggact cagccgaaac aaaggaaaga agaccggaca gaaccaagcc ttttaacaaa 32581 gcatcaaacc agataacatc cagggcatca gataaggcag aacgcacagc ttctccggaa 32641 gaagaaaaca tcgaaggcga aaatgacaga aagctgaaag ggaaagctat ggagaaagct 32701 ctggcagaag ttcttggaat tagtgtggaa gagctggaaa agctcatggc tcagctgggc 32761 ataaattttg agaatgctga cggtgaaacg ggtattcagg aagctgccga taaaatttca 32821 gcatatctgg gtttaaacca ggatgagaaa atggctctgg cagagatgat gtcccttgtt 32881 caaaagcaag ttgaacaggc cttcaaggat gttcagtctg cgtatgatgc tacaagatac 32941 gacatgaagg atgagaatga agcttatggg gtcgagcttt tccatgctga aactgagacg 33001 gcggtggaag atacttcggc gctgagaaat gatttggatg tttccaaagt ttctcaggaa 33061 gtaaaaaata agctcgatga agaaacggac ggtttcttaa agcagattgc cgctaaagtt 33121 gtggaagtgg tacaaaagga tgaaagtaca gccggattga aaacagtgag tgtgaatggt 33181 gaaaacattg aagagattgg gttgaaaact gatgtggaag acatcggcaa tgtcagggag 33241 gcaaaatatt cttcggatga aaaagacagc gccgacaaca gcggaaacgc cggcagcgag 33301 acatcatcca tggcatcaag aggcgttgaa gcggaatctg cagcaaaaaa cagtaacaac 33361 atacaatttg aagcagtttc aaacttaact gttcaaagag caacaggcca ggcagaaccg 33421 gacaaaaccc gaaatattat tccggttaca aataaggaaa tagtcgagca ggttgttgaa 33481 aaagcaaagg tggtattaag cggtgacaaa agtgaaatgg tcattgactt aaagccggag 33541 caccttggga agttggaact caaaattgtt accgaaagag gaatggttgt tgccaaattt 33601 gttgcagaaa atgagcaggt aaaggcagct ttggaatcaa acatgaacat gctcaaggaa 33661 tctttggaaa agcagggctt tttggtggaa gggtttagtg tcacggtcgg agacaacaaa 33721 agacgcgaga acagcagaga caaaacgaat cagggcactg cgaaccaaag aatatccggt 33781 gaaaaactgc aggtgtcgga tatgaccgga gttgaaagaa tgcaaagaat tcatgaaaac 33841 atcgatcctt acagctatgg gagcagcagt attgatttaa ctgcataaca aggaggagtc 33901 ataatggcag tagatgctgt aggccgtcaa aagaccattc aggaaatcat tgacaatacc 33961 acaaacaagt cgactcaaag aaataccggg gaactgggaa aagatgagtt tttaaacctt 34021 ctcattacac agcttcaata tcaggaccct ctaaatcctg tggatgacaa ggaatttatc 34081 agccagatgg cacagttcag cgccctggaa caaatgcaga acctcaataa aagcttttca 34141 gccacaaagg cctttggcat gataggaaaa tatattaccg gtactaccag taacggcagt 34201 gattcaggag ccggttttgt agagggtatt gtacgcagtg tgaaaatgga aaacggaaaa 34261 attcttttgg aagtcaatgg cttggatgtt ccggtggata atgtgctcag tgtttcagaa 34321 gaaagcaatt attattacaa gtacaatagt tcaaatatat cccaatacac cggaattatc 34381 ggctatgaag taagcggaag tgtatatgat ccttccaccg gggacattgt cggcgtgagt 34441 ggaattgtaa gggaaatcca gaaaggtatt tatgaagatt atgctgtaat ggacggtgta 34501 gaggtaataa tttccggaat agacactgaa tttaattcgg cagatccgaa ctttagaaag 34561 gattacctta cagaaaacgt aggccagaga gtttctctta taatcaccga cgcatacggt 34621 tatggattta aggttcctgt tacaggggtt cttaaagatt tcaagatagc accgaacggt 34681 aagattatcg gaattttgga tggggtatat gtgcctgtgg acagcatcag caatataaag 34741 aaaccatctg cgaatacggg cgcggctgac ggcacaaacg aaaacccgca ggttgaacag 34801 tcccagactg aggagtctca agtggaggaa cctcaggtcg gagaaccccg ggacgaagaa 34861 tctgacagtg tatagttgtt taagatattc ggtaaatcac gggatgggca ggtgaggtga 34921 tagtgtgatt gttaataata attattatgt aaatatcagc aggattaacg gaagccagag 34981 agcaatacca tcgggcaaac ctgacggaaa agtacaggga agctttgagg agattttaga 35041 gagcaaggta aacgaaaatc gcggactgaa attttcaaag catgctgaga tgaggcttca 35101 actgagaaat atcaagctta cggatgaaca aaaggaaaag atatcgaaag cagtccagaa 35161 agcggaagaa aagggagtaa aggattccct tgtacttatc gatgatattg cttttgttgt 35221 aaatgtacga aacaggacgg ttatcaccgc cgtaaacagc aatgagctga aagaaaacgt 35281 gtttacaaac atcgacggag cagtgtttgc atgatttttc aatcaaaagt aagaaacttg 35341 cgatatagta ttctatgctg aatttgtggc cggacccctt ccgggaggcc atctctattc 35401 cggactgaca gaaggaatag aaccgatgca ccaacagttg atggttatga ttgaccgtaa 35461 aagaaggagg tcgtttatta tgatgagatc catgttttcc ggagtttcag gacttcaggc 35521 ccatcagaca aaaatggacg ttataggaaa caatgtggca aacgttaaca ccgtaggttt 35581 taaatcaagc agggtgacgt tccaggaagt tttcagccag actttaaaag gagccagctc 35641 tcctgatcca actaccggga gaggaggaac taatcccatg caggtgggat tgggtctggg 35701 agttgcaacc attgacacac tcatgactcg cggaagtgtt caaagaaccg ataatcctac 35761 cgaccttgca attgaaggag acggattctt tattgtaaaa ggcggaagca gtgacacatt 35821 caaattcaca agagccggaa acttcggaat agacagactg ggaaaccttg taaccggaag 35881 cggactgaat gtttatggct ggcagtccta tacgaaactg cctgacggaa cctataaatt 35941 tgacactgaa agtcaaattg aacctataaa tctttattcc gacgatgtga ataaaaataa 36001 aagaatgata gcagcaaaag caactactta tgcaatcttt gaaggaaatc tggatgcatc 36061 ctattcaatt tacagcagcg cagcatccgg cacatccagc aacaatagat tcactatgcc 36121 tgttacggta tatgattctt tgggaaacag ctacaaaata aatataagtt tctggaaaac 36181 cgacgttaca ggcggtgtta ccacatggac atggcaggtt gattcgggaa atggggtaac 36241 agcatcggga gctaccggaa ctatactgtt tgacgatcag ggacaggtaa ttgaaagttc 36301 cgcggttaca cccagtataa caattatacc tgacagcagc gttggaagcc agaatatcaa 36361 tgtgaagctg gacttttcca gacttacaat gtatgcggca gacagttccg caaaagctac 36421 aaatgtggac ggatatccgg caggttcgct tgtgaccttc agtattggtt ccgacggaat 36481 gattatgggt atatacagta atggtcagca gcagccgttg ggacttatag ccttggcaag 36541 ttttgacaac cctgcgggtc ttgaaaaggt aggagagaat atgtatattc cgacttccaa 36601 ctccggagag tttaaaaaag gtgtcaaggc aggcactgaa ggagtgggaa ctttaagccc 36661 cggtacgttg gaaatgtcca acgtggatct gtcaaaagag tttactgaaa tgattattac 36721 ccaaagagga tttcaggcaa acagcaggat aataacaact tccgacgaaa tgctccagga 36781 gcttgtcaac cttaagagat agtatatagg aggatgggga gtgtatggtg gcctgtccgg 36841 catacactct cctgtatata actaattaaa aatttgttaa cgtaatgttt caggttgtta 36901 acgtagtgtt tcaaggatgt aagaaaaatg tcgaataatg tgtttttgct acaaaaagcg 36961 taatattttc ataaaaaata ttaattttct attgagtttt cgaggtaaaa atattatgat 37021 taaattaacg aagttaaatg gcaaaccctt tattttaaac agtgatttaa tcgaattcat 37081 tgagcagact ccggacacaa ttatttcaac aactacagga aaaaaggtag ttgttgtcga 37141 aagtgttgag gaagtagtcg aaaaggtttt acagtataaa aggaaaatct atctttttaa 37201 agacgtgttt atcaatcaag accgttaaca tcctgatgct cttcatgtgt taatcataaa 37261 taccaatgcc tggatttaca tctattccaa agataagggg gcagagaatt tggagcgtaa 37321 aagtagcttt tttgttctca ttggcgtagt tgcatttcta tcattagccc ttgcattgtt 37381 ggcaggatat atcttctttg tacagggagg aagggcagaa ggtccaaatt catcagtcaa 37441 agtggttgtt acgcctaaag acaaagattt gctgaagatg aaactttttg atgaaaagac 37501 acctttcaac cttaaaagtg cggactcaaa gaagatatct gtgatagttg tcaatgttga 37561 actttcctat tttgccaagg ttaagggcat ctctgacact acagccaaaa tagagtcaaa 37621 taaaagcaaa ctgcaggaaa ttgtcggtac atattttcag tcgttgactt tggaagaggt 37681 tatgaagtcc gatgcaaagg aaaaagccag ggcggatctc acaaagatga tgaacgagca 37741 gttactggca aatgaaaata taaattccga cattatatat accgttgtgt tcgatcagtg 37801 gttctaccag tagggggtgc ttggcttggg agatattctg tctcaaaatg aaatagacga 37861 tttactaaag gccctgaata caggtgaact ggatgtccag caaatcagtt ccaaaatcga 37921 ggaaaggaag ataaaaaccc acgatttcag aaggcccagt aaatttgcaa aagatcatgt 37981 aaggacttta aatgttatcc acgacaacta tgcaagaatt atcacaaact tcctttcagg 38041 atatttgagg actctggttc aggtagaagt tatttccgtt gagccgatag cttattatga 38101 attcaacaat tcaatatcaa atcctgcggt gcttgcagtt attgattttg ctccgctgac 38161 aggatcaatt atccttgaaa tggcaccacc tgttgcttat gcactgattg acaggattct 38221 cggcggaaaa ggcttgccaa ttgaaagagt aagggagttt acggaagttg agattgccat 38281 tatcgaaaga attatcatac agcttgtaaa ccttatgaga gagccgtggg aaaacgtggt 38341 ggaacttaaa cccaggcttg agaaaattga aaccaacgcc cagtttgcac agatagtctc 38401 ggccaatgag acggtggctt tgattacttt gggagcaaaa atcggcgaag ttgaaggaat 38461 gattaatctt tgcattcctc atatagtagt agaaccaata gtttcaaaac tgaatacgaa 38521 gttttggttt tccagtgttg aaaaagaagc aacaaaagaa gacaaagaaa ccattcagaa 38581 aaaaattgag tatacaaaag tacctgtcag agcaatactg ggaagagcaa ccattcaagt 38641 ggctgatttt cttgaattac aaccggggga tgtaataact ctggattcaa acgtcaacgg 38701 aaatcttgat gtattggtgg gtgacttgct gaaattccgt ggttctcccg gggttaagaa 38761 aaacaggaat gcgatcaaaa taaccgaagt aataagaagg gaggatgagt agcatggagg 38821 atatgttgtc tcaggctgaa atagatgctt tgctaaatgg tagctcatcg gaagggaatg 38881 aagaaaacag cgcaaatgag gagcttacgt cacaggaaat tgatgcattg ggtgaaatag 38941 gcaacataag tatgggaacc tctgctacta ctcttaactc gttgttggga caaagggtag 39001 tgataacaac tcccaaagta tcagtatgta catgggaaga attagcgaaa gaatatcaca 39061 gttcttatgt ggctgtaaaa gtcgaatata ctgaaggact tgacggtatg aatcttcttc 39121 ttttaaaaga ggacgatgcc aaggtgatta ccgatttgat gatgggcgga gacggcagta 39181 ataaagaggg agaattgacg gatttgcact taagtgcaat cagtgaggca atgaatcaaa 39241 tgattggttc tgcagccact tcaatgtctt cgatgtttaa caagagaata gatatttcgc 39301 ctccgaaagc gtttcccatg acattggacg ctgccgttcc tgaagcggaa tttccaaggg 39361 gcgacaagat agtaaaagtt gcatttaaaa tggttatcgg agaattgatt gacagtcaaa 39421 ttatgcagct tttgcctatc gattttgcca aaaaaatggt tagtaatatt atgaattcca 39481 aacccgagga caatcaggta atagaagagg ttgctgcatc agctgttcag gaacctgttg 39541 ccggacagca taatgagcag tattatcatg ctcaaccgtc tcagcagccg tatcaacagc 39601 cgcctcagca gccgtatcaa caaccgtatc aacaaccata ccatcaaccg tatcagcaac 39661 aatatcagca gtattaccag ccgtatgagc agccacccag acaaaatgat ggataccgca 39721 atcctataaa tgtgcaacct gcacagtttg aagcttttga tgacggttcg aaaatctcaa 39781 ttgacaagaa aaacatcggg cttatcatgg atgtgccgct tcaggttaca gttgagcttg 39841 gacgaaccaa taaacttatt aaagatattt tggaattcgg acctggttca ataattgagc 39901 ttgacaagct tgcaggtgaa cccgtggata ttctggtaaa cgggaaagta attgccatag 39961 gtgaagttgt ggttatagat gaaagttttg gtgtcaggat tacagacata cttcatccgt 40021 cgaaaaggct ttaagctttc atcataaact gtcaatgtcc gggtaaagca aagctaagtt 40081 actgtttaag ttactgtttt gtatttatca gtttgacaat agtatagaca ataattttaa 40141 ggagagggta tcaatgggaa aaaggattct tatagttgat gatgcagcgt ttatgagaat 40201 gatgataaaa gatattttaa cgaaaaacgg ttatgaagtg gcaggagaag cggaaaacgg 40261 agcacgggca attgacaagt acaaagagct taatccggat ttggtaatta tggatattac 40321 catgccggaa gtggacggta tagcggctgt aagagaaatc aagaaaatca atgccgattc 40381 caaaattata atgtgctccg ccatgggtca gcaggccatg gttattgagt caattcaggc 40441 gggagcaagg gactttattg taaagccttt ccaggccgaa agagtggttg aagcggtaaa 40501 aaaagttctg ggctagtttt gcaaaataac agtttactga ttaatagagt gtacagatgg 40561 tcaacggtgg gaaaggaagt ataaaatgga gacttttatc agtgccgtta tgtttaccgt 40621 tgtttttggt tctgtgctct ttttggcata tgtcaccacg aaatttatcg gaaccagaac 40681 aaacaaaatt gttaaaggca aatatataaa aataatcgaa acggtcaatt tgggatttga 40741 cagcaggctt catcttgtaa aggccggaga agagtttgtg ctgatatcaa cttgcgggaa 40801 aaatgtccag atgttggcca aggtgaaatt ggaaggctat tattccgatg aagccgaaga 40861 aactgaaaac gattttaaat tcagggaaat ttttagtaaa tatgcacagg gcttttcaaa 40921 gaagatggaa ggtatgtctt ttttcaaagc ggaaagcggt gagaaagaac aaaccggaag 40981 tgtaccggta tttaatacaa atttgaaccg gcttaaaaaa attacggcaa gtatcgcaag 41041 ttacaagaca gaagatggag aggaatatac caatgaaaac taggctaaaa tatcttggga 41101 ttattttatt aacaataaca gtatttatgt taataacgtc aaatgtttat gcagagcctg 41161 actcaatagc tttgccaaaa ctaggcttta cggtggaacc ttccgacaat ccccaggatg 41221 tttcgaccac tattcagata attgtgcttt taacgattct gtcattggct ccatctatat 41281 taattatgat gacaagtttt gtcagaataa tcatcgtgct ttcctttttc aggaacgcga 41341 ttggaaccca acaaatgccg ccgaatcaag ttttgattgg gctagctttg tttttaaccc 41401 tgtttatcat gaggcctgta ttaacggaga taaatgaaac tgcttttaag ccttacacaa 41461 atcaggaaat tactcaggaa gttgctttgg aaaggtcttc ggatattatc aaaaggttca 41521 tgctaaagca aacatccaaa aatgatctcg gtcttttcgt atcgctttcc ggcatggaaa 41581 cacccataaa agaagaagac attccaaaac ttccgttaac catagttatt ccggcgttta 41641 taataagtga gctgacaata gcttttaaaa taggtttttt aatatatata ccgtttctgg 41701 taattgacat ggtggtttca agtactctta tgtccatggg tatgatgatg cttcctcctg 41761 taatgatatc tcttcctttc aagatattgc tgttcatcat ggtgggagga tggaatctta 41821 tgacgcagat gatagtaaac agttttgtta catagagtgg ttgtgcatta ttttacaaaa 41881 ataaaactat gagaaaggga gagtgttatg gagcagggat tggtaatgga attggcgcaa 41941 aaggcaatta tgacggtttt atatgtggct gcaccaatgc tcgggcttag cttgcttgta 42001 ggtcttgcgg taagtatttt tcaggccacg acccagattc aggagcaaac tcttactttt 42061 atacctaaaa tattgtctgt gctcggagca atagcaattt ttggcccgtg gatgctgaga 42121 gtgttgattg aattcaccca ggcaatttac atgaacataa atcactacat cagataactt 42181 aaatttataa accggaggac aataaattgt ttgttttgga aggaattttg catgttgata 42241 tagaagtatt tatgttaata ttcgttagaa tgacaggtct gttcgtaata gctcccattt 42301 ttggctcaag gaatattccg acatattgca aaatagggtt ttcattcatg acggcattga 42361 tacttgtaaa taccataaaa gttcaggagc tttattttag caatatttac gaatatttta 42421 tccttgtttt gaaagagttt ttggtgggaa ttaccttagg ttatgtggca tatatgattt 42481 tcacggctat ttatgttgcg gggcagttta tagacatgca gattgggttt ggagtggtaa 42541 atgtaattga ccccttgaac agtacacagg tatctattac gtcaaacttt tatttcctgc 42601 tgtgcatgct ggttttcctg atttgcaggg gccattatat attgataaga gcattgtttg 42661 ccagttacaa ttatataccc gtgggaaccg gtgtgtttgg agaggatatg gtaaatgata 42721 tagtaagggt ttttggaaac atatttctga ttgctttcaa aatcagtgca cctattacca 42781 tatcaataat gataagcgag gtggcactgg gaattgtttc aaaaacagta ccgcagctta 42841 atgtatttat ggtgggaatg cctcttaaga ttattctggg attggctgtg atggttatta 42901 caataccgat gtttttaaac cttgttgaaa acctgataac gggtatagac aatgaaatgc 42961 acatttttct caaggatatg gcaccaaaat gaaactgaaa tattttctga aagaagtttt 43021 atcgaagttt ggaaaaaata aagaatttaa aatccatcaa acaagtaccg gaagaataaa 43081 ggcaaactta cagctttttg cggataacgg cgagaaaact gaaaaagcca ctccgagaaa 43141 aagatcaaag gcaagagaag aaggtcaggt acttcagagc agggaactga attcggcaat 43201 agtgcttcta agtgcatttg taacactaag gattttcgga caatacatgt atgaagaaat 43261 tttaaaatgc ctgaaagttg ctataaccgt ttatccttta aatgacggct tgtttacaat 43321 tgatggtttg ttcgaacttt atggtgaaac agtgataact tttttgaaaa ttgccactcc 43381 ggtgcttatg gtggtgctga ttgcaggcat tggttctgca tatgcccagg ttggattttt 43441 gttcactacc aagacactgg gaataaagct aagcaggatt aatcctttaa aaggatttaa 43501 aaggattttt tcactaaaat ctttagttga gcttttaaag tcgattataa aaattgcact 43561 agttggttat ataggctatg gatacatcaa aggtgaaatg acaaatgtat tgggcatgat 43621 ggacgtggat gtggtaagtt ctgcatcgtt tcttggttct acaattttaa acgcggcgat 43681 aagaatgtgt attgcctttg ttgttatagg tgttgccgat tacggttacc agtggtggga 43741 atatgagaag agtcttagaa tgtcaaaaca ggaaatcaag gaagaaaata aagaagttga 43801 aggaaatccg gagataaaat caagaataag gcagaagcaa agacagatgt caatgaggag 43861 aatgcttcag gatatcccga aagcagatgt ggttataaca aacccgacgc attatgcggt 43921 agctattaaa tatgacccta aggaagcaga tgctcctgtt gttgttgcaa agggacagga 43981 ttatatggcc ttgagaataa aggaaatagc aaaagagcat aaagtggaaa ttgtagaaaa 44041 caaacctctt gcacaaacac tttacaaaac cgtggaaata ggcggcaaaa tacctcctga 44101 gctataccag gcggtagccg aggttcttgc ctttgtatat agcttaaaag aaaaaatgaa 44161 gaaatagcat cattggtaac taatgttgca cataaggggt gaaacgagtg aaggccaaaa 44221 ttggagatat ttccgtagca gttatgtttg ttgcaattgt actgataatt atcctgcctg 44281 tcccaagtgg agttttggat attcttcttg cacttaatat atcgttggct gttgtgattc 44341 tcttaaatgt cgtttactca aaagagccgc ttcaattgtc ggtattccct tccttgctgc 44401 tttttactac gctgtatcgc ttggcgctga acattaagtc gacaacattg atacttgcgc 44461 agggagaggc aggagaggtt atccggggat tcggaaactt tgttgcccag ggaaatcttg 44521 tggtgggtgc cataatcttc ttaatcatta ccattgttca attccttgta atcacaaagg 44581 gtaccgagag agtttccgaa gttgctgcaa gatttaccct tgacgcaatg ccgggtaagc 44641 aaatggcgat agatgccgat ttgaatgccg gccttataac tgaagccgaa gccaaagaaa 44701 gaagaaagaa gatacagaga gaatccgatt tttacggggc catggacggt gccaccaagt 44761 ttgtaaaagg ggatgccatt gccggcctca taataaccat aataaatgtt gttggtggaa 44821 ttataattgg tgtgataatg agaaatgaag aaattggcga ggctttacaa aattatgcaa 44881 tacttaccat aggagacgga ctggtaagcc aggtgccggc gcttttgata tcggtggcaa 44941 ccggacttat agttacaaag tccacttccg atgagggtat aagcaatgat ttgagaaggc 45001 agatagttta caatcccaaa gtattcttta tagccgcagg tttttgtata ttgctgtcaa 45061 tacctttggc gacattgcct ttcctggcac tggcggcttt atttataata gtcggcctgc 45121 agcttaagaa acaaagtgtt gaggttgaaa aacaggaaga aatacagatc gagaagaatg 45181 aggttgagga gataaggaaa ccggaaaatg ttgtaaattt gcttcaggtt gaccctatag 45241 agcttgaatt tggctatggt atcatacctc tggcggatgt caaccaaggc ggggaccttt 45301 tggacagggt ggttatgatc agaaggcagc ttgctctgga acttggaatg atagtgccta 45361 taataaggct tagagacaat atacaattaa atcccaatga atatgtgata aaaataaaag 45421 gagttgaggt ggccggtggc gaattaatgc ttgaccacta tcttgcaatg agtccgggat 45481 ttgtggaaga ggagatagag gggatcaaga caacggaacc ggcatttggt ttgccagccg 45541 tgtggataac cgaagcacaa agagacaagg ctgaaatgct gggatatact gtggttgatc 45601 cgccatccat aattgcaact catttgactg aagtaattaa agcccatgcc catgaactga 45661 caggaagaca ggaagttcag acaattattg acaaggtgaa agaaaattat cctgccatag 45721 tggaagagct tgttccgaaa gtaatgacaa tcggagaaat tcagaaagta attgcaaact 45781 tgttaaaaga aggtgtatcg gtaagggata ttgtaacaat actggaaact ttggcagatt 45841 atgcgccgat tacccatgac accgacatgt tgacggaata tgtaagacaa gctcttggaa 45901 gggcaatttc caaaaagttt atcagggata aaaaatctac ggttatcact ttggatccaa 45961 aacttgagca aatgattatg gattctgttc aaaaaacgga gcatggttct tatattaatt 46021 tggaaccaag tgttataaat aaaattttaa acaatttgtc aaagcaagtt cagaaactgg 46081 tgcagctggg ccagcagcct atagttcttg cttcaccttt tgtaagactg tattttagga 46141 gactgtcgga acagtccata ccgggactgg tggtactgtc atacaatgag cttgacccaa 46201 gtattgagat tcagtcaata gggacggtga gcatctgaaa tgaaaatcag aagatacatt 46261 ggaaaagata ctcaggaagc tttgttaaaa gtaaaaatgg atcttggcag tgacgccata 46321 atattaaaca ccagaaagat aaggcagaaa ggttttttca aaatgttttc aaaacctttg 46381 gttgaggttc tggcttccgt ggatgacaat tatggtacaa attccagaag aacagcttat 46441 gaaagcagag gaaaaaatga cagaggatat gatgtcgtat caggtggtaa tttgagttat 46501 aatgaaaatt taagaagtaa atttgacgaa aaagaggaaa aaatacatct tttagagaat 46561 aaaataattg gcatggagga gaaaatcaat aagatttatg agcaaatcca aaaaccttct 46621 gaaaagctga ttgctgcgac aaatgatgat aatgagcagc cgcagtccaa agttcttgat 46681 ctgttttaca acaatctgtt gaaaaatgaa gtggatactg agatagtaaa acagcttatc 46741 agtgttgtga gaggaaaggt aaaagaaaat gtaagtgtca gtgaaactgc atcaatactc 46801 tacaacctta tttcggaaat gatgggcaaa ccttcggata taaagctgag gaatgacggc 46861 aagccgacgg tagtgatgct ggtagggccg accggtgtgg gtaaaaccac cactttggcg 46921 aagattgccg caaattattc attgaatctc aacaaaaatg tcggattgat tactgccgac 46981 acatatcgta tcgcagccgt ggagcagctt aaaacttacg cagatatact gggaatgcct 47041 cttaaagtta tatattcggc caatgaaatt caagatgcaa taaaagaata cagtgataaa 47101 gatttgatac ttattgacac tgcgggaaga agttataaaa acaaagaaca ttttgacgag 47161 cttaagacac tggtcgaggt aaccaatgcc gatgaaattt atctggtgtt aagtactacg 47221 acaggtatga gaaactgcag ggaaatcatt gaacactata gctttttgga aaactacaaa 47281 cttatcttta caaaactgga tgaaagttca gcgttagggc ttatacttaa ttcaagacgc 47341 ctgaccaata gggatttatc atttgtcaca accggacaga gtgtgccgga tgatattgag 47401 cttgcgaatg ttgacatgat aacaaaaaat ttgttgggga gcatttcgta gatgatagat 47461 caagcagaaa aactcagaca aattatagac gatttgaaat tcagaaatgc tgtgacttta 47521 gataatccct caggcgtcag ggaaaaaacc gccaaagtca tcactgtaac cagtggaaaa 47581 ggcggtgtgg gcaagaccaa tatcacaata aatcttgcca tagccttaag tgaacttggc 47641 aagcgagtta caattttgga tgcggatttt ggattggcaa atatcgatat ccttttaggg 47701 attgtgccca aatatacact ggtggatgtt ttgtatgaca agaaaaatat acttgaggtt 47761 ttgaccgacg gacctaaaaa cataaagttc atgtccggag gttcaggtgt tgaagaactg 47821 gtaaagcttg acagcacgca gcttgagaag tttgtcagca atatttctct tttggacaaa 47881 ctgtcggacg ttatactgat tgacacggga gcaggacttt cggaaagtgt gatgagcttt 47941 gtgatggcgg ccgatgaggt gtttcttgta acaactcccg agccgacttc cattacagat 48001 gcttatgcac ttataaaaat gatatcaaac agggaaaata acaaaataat aagggtggtt 48061 gtcaacagag ctgaaaatgc aaatgaagca aaagacatac tgaacaggct ttcaatggtg 48121 acggaaaagt ttcttgcaat gaagctttat ccgctgggat ttatccccca ggacgaatcg 48181 gtaataaaag cggtaaaaat gcagcagccg ttttctttga gcttccctaa atgtgatgcc 48241 acaaagcata taaaagagat ttcaaaaaga cttatagaag gaagtaccgg cctgtccaat 48301 cggcaggaag gtggaataaa gggctttgtg cgaagactgg taaaccttat gaatgcttga 48361 cggcaaaaaa tcgtatcagg agtatttata cggaggtaaa atatgaggtt taatgaattg 48421 ggcgtagggt tgaagctcga attaaaactt gaaggttcgg atgaaaaaaa cggcgattct 48481 gtctttgtca gcgaatttga atgggctgaa aatgacagga taatatatat tgcagctccg 48541 ataaaggggg gaaaaattta ccctgtcagt gtcggtgaag aacttgccat agtgtttata 48601 aaaagcgaca acctttatga atttaaagga aaggttattg gcagagaggt aagacataat 48661 ataagtcttt tgcgggttga aaccttgtct gagataagaa agatacaaag acgggatttc 48721 ttcagatttg attgttcaat tccgataagc tacagggtag tggaaaagga tagaatcaat 48781 atattacaaa gaagatttat aaagtcatat accagagata taagcggcgg aggggtgtgt 48841 ataaggctta aagaaagaat cgagaccgga gagcttctgg aatgtgaatt gttcttgaat 48901 gattttaata aagtaagttt tttgggaaga gtggtaaggc ttacagaata cgacagcaaa 48961 aatgatgttt ataaatatga gataggagtt aaatttgaaa agattgagga aagagacaga 49021 gaaagaatta taggatatat atttcaggaa caaagaagac ttataaaaaa gggttgatat 49081 tgcgatatga tttggaatct gaagcaaaaa atcactgtgt tggtagttga cgattcagcc 49141 tttatgagaa aagtaatatc ggatattcta aacagcgatg aagaaatcaa ggttattgat 49201 acagcaaaaa acggtcttga ggctattgaa aaggcgcaaa agctaaaacc ggacgttatt 49261 accctggact tgaagatgcc tgttatggac ggcctcgagt gcttaagaaa actgaatgaa 49321 accatgcgca ttccggttat tatgttaagc agcattacca aggagggagc ggaggcaacc 49381 attcaggctt tggccgaagg agcaatggac tttgttgcaa aacctgaaaa catatttgat 49441 atgaaagaag aaagaataaa gaatgagata attgaaaaag taaaaattgc aaaaaactac 49501 aaatatttta aaagcgacaa aaagagcacg ggtactgtaa taaaagccaa tacaacccaa 49561 agcaggattc gcaatatcgt agttattggt acttccaccg gcggaccgag ggcacttcag 49621 gatgttttgc cgctttttcc ggcaaatgtg gacgcagctt ttttgatagt acagcacatg 49681 cccggaggat tcacaaaatc tttggctgaa agacttgatt ccatgtgcaa tgtaaaggta 49741 aaagaagctg aagatgatga gattattgaa aattcccatg tatacattgc tcccggagac 49801 ttccatatgc ttcttgagaa gaatggcaat gatacattta aaataaagct ttccaaagat 49861 cccccgttgg gaggtcacag accgtctgtt gatgtaatga tggaatcggt gtccaataca 49921 ggatttaaaa atgttgttgc ggtcataatg acagggatgg gacgggacgg aagtgaaggc 49981 atcaaaaagc tcaagagtgt aaacaatgca tatataattg cacaggatga aagctcatgc 50041 gttgtatttg gtatgccaag ggtcgcaatt agcaccggag tagtggatgt tgttgtaccg 50101 ctgaaagaaa tagcgaatga gattatgaaa atagtggggg tgcatgaata atggacatga 50161 gtcaatacct cgagattttt atcgacgaaa caaaagagca cttgcaaagt ttgaaccaat 50221 cactgcttga attggagcaa aatccggatg atacatcggt tctgaatgaa atattcagag 50281 ttgcccatac attaaaaggc atgtccggta caatgggttt tactaaaatg gcaaagctga 50341 cccatgatat ggagaatgtt ttacaggcac tgagaaacaa tcaaataaaa gcaacttcaa 50401 aacttgtgga tttgctgttt aaatgccttg atgctcttga aaactatact gataatattg 50461 taaacaccgg aaatgaaggc agcaatgaat ataacgatat cattaaggaa cttaatgata 50521 tcgttcaaac gaaatcatct gacggaggac agcaaaaatc gtctttatcc gggaaaaaag 50581 tttcggacct ggatggaact tcaaaagagg aaaatcaaca tccgactgcc gcaatcaagc 50641 ttaatcagta cgaactgaat gttgcagcca aagcaagaga aatgaatatg aatgtcttta 50701 aaattacagt cgtactgaat aaaggctgtg ttttgaagtc ggccagggca ttcattatat 50761 ttcagacatt ggaaagacat ggggagatta tcaggtccga accgaaagtt gaagacattg 50821 aagatgaaaa gtttgatttt gaatttaccg tagtatgcgt gacaaaagaa aacgaagagg 50881 tatttataaa ggatattaac ggaattgccg aggttgacga agtaattgta gttccgatag 50941 atattcctga gctgaaaacc tcaacagttc agaatgatga caattatgag cgggaaaatg 51001 ttcaaacagg cggagaagaa gtgcatgtcc aggaagagaa aagtgaatcg aatacttcat 51061 ctcaggtcca taaaaccaaa accggaaaaa ctgtcagggt tgacattgac agactggatg 51121 tattgatgaa tcttgtaagt gagcttatta tcattaaaac cagacttgcc ggccttagcg 51181 gaagtgataa tgctcaaact tataatgaga cgattgagta cctggatcga ataacaacaa 51241 gtctcaatga cgcagttatg aaggttagaa tggtaccggt tgagatggtg ttcaacagat 51301 ttccgagaat gataagggac attgccagag agcttggaaa agagattcag cttaatatgt 51361 ccggtgtgga aaccgaactt gaccgaacgg ttattgacga gataggagat ccccttatcc 51421 atttgcttag aaactcggca gaccacggga tcgaaccaaa agagaaaaga cttgcgatgg 51481 gcaagcctgc cgtcggacat attaatttgc gggcttatca ggatggagac aatgttgtaa 51541 ttgaagtaga ggacgacgga cagggaatag atgtggaaaa ggtaaagaaa aaagctgttg 51601 aaaaagggct tgtaaagaaa gaaatagtca ataccctgtc acagaaggat attattgatt 51661 tcctgtttaa accgtccttc agcacttccg acaacattac aaacatatcc ggaagaggtg 51721 tggggcttga tgtggtaaaa accaaaatcg agcagcttgg aggtgttgtt gaagttgaaa 51781 cggaggcggg aaaaggaagc aagtttataa taagacttcc tcttaccctt gcaataatac 51841 aggcgctttt ggtaatggtc ggtaatgaaa aatatgcaat acctcttagc agtaccaagg 51901 aaataataaa ggtaactccg gaacagataa agacggttca aaagcaggag gtaattttgc 51961 taagaaacat ggtggttccg atagtaaggc ttgataaaat tttggaagtt cctccggtgg 52021 aaagaaaaaa gaaagacatg actgtggtta ttgtaaaaaa aggagaaaaa ctttccggct 52081 ttttggtaga ttcgctgata gggcagcagg aaattgttat aaaatcactg ggcaagctcc 52141 tttcaaacat taagggaatt gccggtgcca ctatattggg agacggaaat gttgcattga 52201 tactggatgt taatttactt gccgtgtaga agggagttga aggatgtgga agaaagagcc 52261 aacatggaaa gcaaacaata tgttgttttc aaactgggaa aggaagacta tggactggac 52321 attcaaaagg tgacgacaat tgaaagaatg atgccggctg caagggtacc gaaaactccc 52381 gattatataa agggtgtaat aaacctaaga ggagaaataa tcccagtaat ggatcttaga 52441 aaaaaattcg gcttgcctcc ggttgaggag actgatgaaa cgaggatcat tattctgaag 52501 tttgatgata ttacttttgg aataattgtg gatgaagttg atgaagtact ggatttgaca 52561 gaggaatcca tagaaaatgt atcaagtttt tccaatgatg tttcgatgga ctatatatac 52621 ggagtcggca aagtagggga caggattgtt actcttttaa accttgaaaa gcttacggat 52681 attgatgaag aagacaaaca aggggattag gaaaatgagt gtaaattttg ataatcttga 52741 caatatacaa attgatgttt tgcgggagat aggaaatatt ggctcgggga atgcagctac 52801 tgctttggcg aagatgttga ataaaagagt taacatggac gttccccaag taaaagtgct 52861 tcagtttcaa gaagtgagcg atattttagg tggtgccgaa attccggtgg ttggcctttt 52921 gcttagggtt accggtgaca taagcggcag tataatgttt attcttgaaa aaaaggctgc 52981 cggtgttctg gttaacatcc tgatggggaa acctttggat gaaattgttg tcttcgatga 53041 gattgcgatt tcagctctga aggaagtagg caatattctt gcgggttcgt acctttcggc 53101 tttatctact ttgacgaact taaacatact gccgtcggtg cctgaacttg caattgacat 53161 ggcgggagcg ataataagtg ttccggcaat cgaattcgga aaacttggag attcggttct 53221 gttcattgaa actgaattct ctgaaggcag tacaaaagtt gtgggaaatt tcttccttgt 53281 tcctgatatt gattcttatg aagtattatt aaaagcatta ggagtcgcta attaatggga 53341 aatattataa gaattgggat ggctgatttg aaagcatcgc atcatcctgc gatattaact 53401 actctgggac ttgggtcatg cgtgggaata gcactttatg acagaactac aaaaatagtg 53461 gggctggctc atgcaatgct tcctgacagt tcccaggtaa aaaataaaac taacgccgca 53521 aaatttgtag ataccgctat tgaactcctt gtgaaagaaa tgctgagtct tggcgcgtca 53581 aagaaaagaa ttgtcgcaaa gctggccgga ggagcgcaga tgtttacttt tacacaagga 53641 gccgaattaa tgcgtatcgg tcaaagaaat gtggcggcgg caaaaagcaa actggagagt 53701 ctcgacattc ccgtagtctc cgaggatacc ggaggtaatt acgggcgtac tgttgagctt 53761 gattcggaga gcggcatgct cctgattaga accataggat atggaactaa acaaatatga 53821 gagaggattg acaaatggac tacatgcgca aaatgccgtt tataatgggt gcttctgctg 53881 cgattgtaat aggaataatc agttataaca atggctatga cctaaaggca atttgtgtca 53941 gaatgacagc cggtatgatt ctcttctttg ctgccggtgt gttgctaaga aaggttataa 54001 acagtattta tgaagaagta aaggaaaaaa gtgagcttca aatccacaat accaatgaat 54061 ctcagaatac cggtaaaaaa gaacatgaaa aaaatcatgg aattgattat agagtaggcg 54121 acgaaacacc gaacttgaaa aataatgaaa aaattgaaga caacgtgctt tatgatgaag 54181 agttcagacc gcttgaagca agccgtgtta cagttaagga cgacaaacaa taagtttcaa 54241 atttatatat atatataaat aaaaaatggg taatggggga ttaatatggc atccgcgagc 54301 aacaaacaac tggaattatg gaaacagtat gctgatacta aaaatcctgc gataaaagaa 54361 caactgatta ttgaatactc aaatattgtc aagtacattg caggcagact cagcatatac 54421 tttggttcca atgttgaata tgatgatttg atcggatatg gaatatttgg cctcattgac 54481 gcaattgaga agtttgacat caacaaggga gtcaagtttg aaacttatgc gtcgttaagg 54541 atcaggggct caattattga cagtataagg gagctggatt gggttccaag atctttgagg 54601 cagaagaata aagaactgga aaaggtctat gccgaaatag agaatgaact tggacgttcc 54661 gcttcggaca aagaggtggc ggacaagctt ggaataaccg tcgatgaatt gaacaaacta 54721 ttaaatgaag taaatctttc atcgatgata tctttggaag agtttttgga gcaaaactat 54781 gagataggtg ttacgacagc tccggaaagc agggatgaaa aacccgaagg ttatatagaa 54841 atggcggagc tcagagaaat actggcagat gctataagca aactcccgga gaaagaaaaa 54901 atggttatta ctttatatta ttttgaagat ttgacattga aagaaattag tgcgataatg 54961 aaagtgtcgg agtctcgaat ttctcaattg cacaccaaag cgattctgcg tcttagaggt 55021 aagcttgcac gtcacaaaag tattttaagt gattgacaaa gtttataatc aagcaaaaaa 55081 aggggggata cccgcatgag agatgttacg aaaggctcat tcaatgacag tccgaataac 55141 ggtttttttg agatccagta taaggaagac ggagtatatc ttacagtgca tccgccaata 55201 ggaaaaggca aggcggttga agtaaacgat gtaataagca ggcttacgca gaagaaaatt 55261 gtctatgata aagaaatggt tgaattggct gttcagagag cgtcaaacgt acctgtgaaa 55321 attggcgaac ctcaggagga acttaaactt gatgcgacaa tagatgttaa catttccccg 55381 gacaaaatga aagcaacaat ggtaataaga ccccctgacg gtggaagaat gcttactaaa 55441 gacgagatga tggagatttt gaaaaacagc ggggtaagat acggaataaa cgagtcaatg 55501 cttgagaatg tttcaaaata tcctgtctat aatgagatta tagtaattgc cgaaggtacg 55561 cctcccataa acggacagaa tggaaaagtg gaattccatt ttgatttgaa aaaagaaaga 55621 aaacctacta tccttgagga tggaagggtg gatttcagag aactgaatct tattgaaagt 55681 gtaaaaaaag gacaggttct ctgtacactg gttcctccgc ttccgggtac accgggcaga 55741 acggtggagg atatcgaggt tccggctttg gacggaaaac ctgccgtgct tccaaaaggg 55801 aaaaatgttg aaataagtga agacggacaa agtcttattg ccggcataga cggacaggta 55861 aattatatag acggcaaggt aagtgttttt gccaattatg aagttcctgc agacgttgac 55921 aactccaccg gaaacataag ttttgtaggc aatgttatca ttagaggaaa tgttttgtcc 55981 ggttttaccg ttgaagccgg aggcagtgtt gaggtaatgg gagtggtgga agctgccgtt 56041 ataaaggccg atggtgacat tattctaaga aggggaatgc aggggcttgg aagaggaata 56101 ttaaaaagcg gcggtgacat aattgcaaaa tatatagaaa acagcattat tgaagccaaa 56161 ggtgacataa aagccgaggc aataatgcac agcaacgtaa aatgcggaaa caagctggag 56221 ctttccggca agaaaggtct tttgataggc ggaaaatgca aagtgggaaa agaaatagta 56281 gcgaaggtta tcggttcgta tcttgccact cacaccgata ttgaggtggg tgttgatccg 56341 cagattaaag agcgctacaa ggagcttcgg gatgagattc ggaaaataga agaggatttg 56401 gttaaagcgg aacaggccat aacaatatta aagaagcttg aggccgcagg aaagcttact 56461 ccggagaagc aggaactgat ggccagaagc attagaacaa agatttatta ttcgaacagg 56521 cttggtgaat taaaagaaga attgataata acagagcaaa ggcttcagaa ggaggctgac 56581 ggaaaaatca gggtatttga tcatatatat ccgggaacaa aagttacaat agggacgagc 56641 atgatgtatg tcaaagagga cctgcaatat tgtacattat acagggacgg ggctgatata 56701 agagttgggc ctattgacaa ataaaattat atttatggaa gtgatggcgg atgtcgatta 56761 aacccattga ttttcagatg atgattccaa aaacagccga gatatcaaaa atacaaaatg 56821 atcaacagca gaaaagtgtc gttgttaatg agcagcaaac caatataaca cggcagaagt 56881 tcgaggaaaa cgttaatacc gtgcatgcaa gggaaaatgc tgaaaaagtg cgaatagaca 56941 gtgaacagaa aaagaaaaag gaagaaagag gccggaaaaa aaatccaaac cgagccaagt 57001 acggaacaaa aggagaaaaa gagccggaag aacaaacaag tgtgatagac ataagattat 57061 aaatttaata ccagacaaag gataaaggag tgatgaaatg acgggttttt atgcaagtat 57121 gatgtttata gggatcttat tgataattgt gtccctggtt ttaatttttc tggataagtg 57181 gaaatcgagc gaaactgaga agagaattga tcaaaaaagg gaggaacttg caaaaattat 57241 tgcagatgca gatcttatgg ttcaggagct gaacaaattt tccgattata tcatttccca 57301 agtggagcaa aagaataaag aaacgctcga tttgattaaa aatgccgagg agaggctgga 57361 aaagttaaca aaagagtatg ccagtgcatc aatggattcg ggcaatgaaa agtttgttac 57421 caatacggaa gattcctatg caggcggtaa gtctgatctt gtcattgaaa acctgaagtt 57481 tgaagaagat gcgcctgtaa gtgctgcaaa accttatcag ataaaacttc agggcgtaaa 57541 ggatgagaaa gtcataccca taaacagcaa gcataaggaa gttttagcat tggctcaaaa 57601 aggtcttaat gaaactgaga tagcgaaaaa gctgagcatg ggcaagggtg agatacagct 57661 tattcttggt gtaaacaaat aaaagaactt tatttttgtt tgcgggggat tgtatgggaa 57721 ggtttcacat taaaaacata ctgttgggta ttggaatggg tttggtgctt acggcattga 57781 caggtattat ttattctgcc ggaagggaac ctcaaatgag caaagaggaa ataatggcaa 57841 aggcaaggca gtatggcatg gttccaagca acgagataat tgaagaatct gaaaacgaac 57901 tggttgatga ggaagaagcg gaggtggagc cggccggaaa acaggtggat aatgaaaata 57961 tacaggttca tgcgagtgat ggcctggaaa acaacgaaga aatgaaatca caaccgactc 58021 aaaatccgga agttaccaaa gatgtgccgg ttcaaccaac cgcaaatccg gataatgctg 58081 aaaatgtaca gatccagcct gcatcaactc cggagaacgt tgaaaaaaga caggttaaaa 58141 taaagatagc tccgggggat aattcgtatg ttatttccaa aaagcttgtt gaagaagggt 58201 tgatagataa tgccaattcc tttataaatg aaatcagagc aatgaagctt cagacatcta 58261 tacaggtggg agaatacact attgaggaag gaactgatat taaaaccatt ataagaataa 58321 tttgcaaaag aaaaaaaata taaaggaagg cttaattatt caaggctgat tatcaaaaac 58381 agggattaaa aaagagcttg ataaatttaa gctctttttt attttgtgca aatttattat 58441 gtgcaaaaat tcaaagggta aaattattgt tttgcggcaa taatcgataa tgggaaatat 58501 ttgtaatgct ttcagttgat gtgttattat gtatcaaaat taaaagtttc aggaaagagg 58561 tggatggttt gagaagcaaa attattgtac ttgcagcctt gattcagctt attttatttt 58621 caggatgcat gtcttcagaa cttgttttag gaccaaaaaa ggaagtaagt ttgtacagtg 58681 aaaagattgt agaggccgga gggcctttag ttttggacat tttctgtgat tcaggcaaca 58741 ttgaaatgta cacttgggat aaagatggag taaagtttga aatgacaaaa agggtaagag 58801 gaactgaaag tgaagagatt ttgtctcaaa aaactcaata atttcaatat tgacataaac 58861 gagaacgaaa ataaaattat tttcaagtcg gagtacaaag gcaaagataa aaatcccatt 58921 gacaaaagca ttgatttaaa aatatatgtt ccgaaagctg aaaaaacctt aaacttaaaa 58981 ctggatatcg gaaatataaa attctacgac gatatcaagg gagttttaaa cgctgatata 59041 aacatggcaa atatggagat taacaggttt gtcggtgtgg tgaatatcga aggggatgtg 59101 ggaaacgtaa aaatatccag cggcaaaata tccggaaaat ccagtatagt caagaacata 59161 ggaaacataa gcgtaaaggc tgaatttgaa gaaggaggag attatacttt taaaaccggg 59221 acaggaaata ttgatttaat gcttccttac ggctcaaaag tttcttttga aagtgtggga 59281 gagctggagg taaatgaatt taatgacttt aatcactcta caaaagcaaa ggtggaaact 59341 tcgatgggca aaattgcaat cacgggatat tagataaatt tttatttatt cctaagatat 59401 ttatgatatt tatatttatg atatactttt gttgaggatt gaaatatgaa atgggttata 59461 tgtgattaaa tcccttgtgt tatgaattga cggttgttcg cgaaataacg gcaggaggac 59521 aattatgaga acttttgtag cggttgattt taatacggaa ttgaaaaaag aaatattaaa 59581 acttcagaca caacttagaa atttggctgt ttcgggaaga tggaaatata ttgacaattt 59641 tcaccttacc ctgaaatttc tgggtgaaat agaaaaatcc aaggttcaag atattaaaaa 59701 agggcttgat gaggtatgtg gcaaaaccca aaaattttgt cttaatatag acggacttga 59761 tttttttccg ggaaacggct gccttagggt gctgtggttg aagcttgccg gtgagcttga 59821 aagccttcac agccttcagt cggaaataga cataatgttg gagaaactgg ggtttgaaaa 59881 ggaaaaaaga cgctatgtgc cgcatgtaac catagcacag gatgtggtgt tcaacaagga 59941 ttttgaagaa attaaaggtc ttgttggaaa ctatcggttt gcaacaattg aagttcagag 60001 cgttaatctt tttaaaagcg agcaaatagg tggcaaacgg gtttacactc cgttgacgga 60061 gcacaagctt gtttagttga caagatatgc agagtggagt aaaattagcc gcggatgcta 60121 ctttagtttt ttctaatctg attatggtta attttaatat aaaaaaggag atttaacatg 60181 agaaaaaaat atgtagcatt ggcggtaatt gtttttctta taggaatttc agctcttggt 60241 ggctgtaatt tcagatctga cagtgttgcc gttgtaaatg agaaaaatac cggcacttat 60301 gaaaatgatt tggatcaaaa gaaagtagcg gatgctgcaa aagacggcac agttggtact 60361 gtaagtgaaa ctgtttacag caccgtccaa cccacggcaa ctcccgaaaa agagttaaag 60421 attgttgcgg tgggagacat tcttttgggc cggggtgtgg gcatgaggct taaaaacggc 60481 aataaagact ttacatatcc ttttcttgag gtcaggtaca tcctaaggaa aggggacgtt 60541 gtgtttggca atctggaaga gcccattaca tcaagcactc attcccttac aggcataaaa 60601 gaaggcggaa aatatgtgct caaaaatgat gttgaggcga tagaggggat taagtatgcc 60661 ggatttaatt tgatgaacct tgcgaacaac cacatacttg attattatga gcgcgggctg 60721 tttgatacga tggatatttt ggataaaaac ggtatcaagt atgccggagc gggaagaaat 60781 ttggaagaag ccagaaagcc cgcaataatg gaagtaaaga gcatgaaagt gggaatgctg 60841 gcttacaccg atatggcgga aattgtgtac aagggcaatc cgaactacaa gtttgcggcc 60901 ggagaggaca agccgggggt tgcaccaaga cctttgaaat ttgacgattc cataaaaaaa 60961 gacatagaag agttacggag caaggtggat attttaattg tttcacttca ctggggagtg 61021 gaggaaagct ttgaagttct gcctgaacag agggaatttg cccacagtct tatagataac 61081 ggagtggatg taatattggg acaccatccc caccagttcc aaggtataga aatctacaag 61141 ggcaaacctg ttttctacag tctgggtaat tttatttttg atcagaacga tcccgaaaac 61201 caggagtcct ttattgtgac acttgattac aaaggcagca gactgacagg aatagaggct 61261 gtacccgtga gaacaatcgg aaaaatacag gtagttcctc aaaaaggaga tgaagcaaaa 61321 cctattttgg aaagagagaa aaatttatgt aataggcttg atacaaactg cattataaaa 61381 gatgacaaat tatattttga aattggaaaa taatgataat ataattaagt tggacgtatt 61441 ttgacaaaat aaaatcataa agtggttgca tttgtcgaga tttgtgatat cattggatag 61501 taaattatat tttaggttaa aaatggaaaa atagtttttt atttaaactt tatttttaaa 61561 ctttatttaa aatatcaaaa taattgcctt tgtattttac ttattgtaca atatatttgt 61621 acaatatatt aaggaaaaaa atacttttgt agcgacttaa aagtcaattg aatggaccaa 61681 taaaggacct tttcaaattt gtcaaggtat tttaggacaa ttttttttat tttggatatt 61741 gttcttgttt attgggtaaa tatatagtga cattttagat ttgaaaggga tgagaaggat 61801 ggatgcatgg cgcggattta ataaaggcaa ctggtgccag gaaattgacg ttcgtgattt 61861 tataattaga aattatactc cttatgaagg cgatgaaagc tttcttgtag gacctacgga 61921 tagaacgcgg aaactttggg agaaggtttc cgaactgtta aagaaagaac gggagaacgg 61981 cggggtattg gatgttgata cccatacaat ttcaacgatt acgtctcata aacctggata 62041 tatagataaa gaacttgaag ttattgtcgg gcttcagacg gatgagcctt taaaaagagc 62101 cataatgccg tttggcggta tacgtatggt gattaaggga gccgaagctt atggccacag 62161 tgtggaccct caggttgttg aaatattcac aaagtacaga aagactcata accagggagt 62221 ttatgatgta tatactcccg aaatgagaaa agccaaaaaa gccgggatta ttacaggact 62281 tcccgacgca tacggcagag gaagaataat tggcgattac agaagggttg cactttatgg 62341 cgttgacagg ctgattgctg aaaaagagaa agaaatggca agtcttgaaa gagattacat 62401 tgactatgag actgttcgag acagagaaga aataagcgag cagattaaat ctttaaaaca 62461 acttaaagaa atggctttaa gttacggttt tgacatatct tgtcctgcaa aggatgccag 62521 agaagccttt caatggttgt attttgcata tcttgcagca gtcaaggaac agaacggcgc 62581 ggcaatgagt attggaagaa tttcgacttt ccttgacata tacattgaaa gggatctcaa 62641 agaaggaaaa ctcacggagg agttggctca ggaactggtt gaccagctgg ttataaagct 62701 gagaattgtg agatttttga gaactcctga gtatgaaaag ctcttcagcg gagaccccac 62761 ttgggtaacc gaaagtatcg gaggtatggc gctggatgga agaacgctgg ttacaaaatc 62821 ttcgttcagg tttttgcaca ctcttttcaa cctgggacat gcaccggagc ccaaccttac 62881 agtactttgg tccgtcaatc ttcccgaagg ctttaaaaag tactgtgcaa aggtatcaat 62941 tcattcaagc tccatccagt atgaaagcga cgacataatg aggaaacact ggggagacga 63001 ttatggaata gcatgctgtg tttctgctat gagaattgga aaacagatgc agttcttcgg 63061 tgcaagatgc aatcttgcaa aagctcttct ttacgctatt aacggcggaa aggatgaaat 63121 gacgggagaa cagattgctc cgatgtttgc accggtggaa accgaatacc ttgattacga 63181 ggacgtaatg aagaggtttg acatggtgct tgactgggtg gcaaggcttt atatgaacac 63241 cctcaatata attcactaca tgcatgacaa atatgcctat gaggcgctgc agatggcatt 63301 gcatgacaaa gacgtgttca ggacgatggc atgcggaata gccggtttgt ctgtggtggc 63361 agactccctt agcgcgataa aatatgcaaa ggttaaaccg atacgcaatg aaaacaacct 63421 cgttgttgac tacgaagttg agggtgatta tcctaaattc ggaaataacg acgaacgtgt 63481 tgatgaaatt gcagtgcaag tagtaaaaat gttcatgaac aagcttagaa agcaaagggc 63541 ttacagaagt gccactccga ccctttccat acttaccata acttcaaacg tggtatatgg 63601 aaagaaaacc ggaaacactc ctgacggcag aaaagctgga gaacctttgg cgccgggagc 63661 aaatccgatg catggaaggg atataaacgg agcattggct gtactgaaca gtattgcgaa 63721 gcttccctat gaatatgccc aggacggcat ttcatatact ttctccataa ttccaaaagc 63781 tctgggaaga gacgaggaaa ccagaataaa caatcttaaa tcaatgcttg acggatattt 63841 caagcagggc ggccaccaca taaatgtaaa tgtgtttgaa aaagagacac tgttagatgc 63901 catggaacat ccggaaaaat atccacaact taccataaga gtgtccgggt atgcagtgaa 63961 ctttataaag cttacacggg agcaacagct ggatgttatt aacagaacga ttcacggaaa 64021 gatttaatta aaagtaatag aagggacggg gcaatgacat taaagggcag gatacactca 64081 tttgaatctt ttgggacact ggacggaccg ggtataagat ttgtggtttt catgcagggc 64141 tgtcccttgc gttgtatata ttgccacaac agggatacct gggatgttaa tgcggggagt 64201 gagtacactc cccggcaagt aattgatgaa atgatgaaat acatagacta tataaaggtc 64261 tccggaggcg gaataactgt taccggcggg gagcctgttc tccaggccga ttttgtggcc 64321 gaggtgttca gacttgcaaa agagcaggga gtgcatacgg cgctggatac caatggattt 64381 gctgacatag agaaggttga aaggcttata aaatacaccg atcttgtatt gctggatata 64441 aagcatgccc gggaggataa acataagata attaccggtg tgtccaacga aaaaatcaag 64501 cgttttgcgc tgtatctttc ggaccaggga gtgcctatct ggataagata tgtccttgtc 64561 cccggatata ccgacgatga agatgacctt aaaatggcgg ctgatttcat aaaaaagctt 64621 aaaacggtgg aaaaaatcga agttcttcct tatcacaaca tgggagcata caaatgggaa 64681 aaacttggtc agaaatacat gcttgaagga gtaaaggggc cgagtgcgca agaggtggaa 64741 aaagcaaaga ggattctgtc aggcaaataa taaaagcttt tttcttttat tatttgcttt 64801 tttctattac caatttgctt tgcttaagtt taggtttggt tttgatgagt tttttaatgt 64861 ttcttttata tttatctttt atatgaacag tgttgtaaac ttccaaatcc agtttgtcaa 64921 atattgattt aaaaatcttt gccgtatact gggcgtcagt taatgcccgg tgaagatttt 64981 cgtctatttc aactccaatc aaggccagag cattttcaag gctgtatctt tgacccgacg 65041 gcagatgata aattgctgaa aactgttttt gaatgtcaat gtttctttta agccagtcaa 65101 tttttattct gttgaattta cagttcaata tcagattgag tacatcgtcg tggccccaac 65161 tgattagaag atagtcgtct ccaatccatc gaataaattg ttttatgaca tttctgaaac 65221 tgtccgcact gttaatttgc tcctgagtaa ttttggtttt ttgcttaacc acggaaaaaa 65281 gttttttaaa gtattttggc ttgatgaaag agctaaacat gcctatttcc tgcaggtttt 65341 cattcagctt tattgcccca atctcaataa tttcattggg aatactgctt ttaaagggtt 65401 tactgttaag ttccaggtca tatactatgt aattcatgcg cttatctcta ctttcttttt 65461 agtttttaat ttgtttttaa ttaaatctgt cgatggtcat tgaaattatg ttcaaaacca 65521 ggtttattta taatctatta tgttatgaaa aaccgtgttt tataacttta gggacaatgg 65581 tattttaagc tatacagcat tatttgtcca tacctgggtt aacatattat cactgaaaaa 65641 gggagattat atatttgtaa tactttttat tattaaattt ggagtggtgt tcatgaagtt 65701 aaaatttggc gtaataattc ttgcagtttt tttacttgca ggctgcagct ccaatataaa 65761 ttatgatgac aaaaataatg ttgaatttac aaggcttaac caggagaata cacttgatgt 65821 gggttctgat caaatcagga tactgagtgc caatacaaca gtgggctatg aagaatatgc 65881 aagcatcagc ataatcggta aacccgagga aacatatacc ataacgtcaa gatacaaatg 65941 gggcggagaa gatgtcactg tcgttgagaa aaggaaggca aacagagacg gagttgcgac 66001 atgggtgtgg aaggtgcggt caaacacaat accgggaact tatccgatag taataaccgg 66061 gggaaatcag cggattgaaa catcctatac ggtccggccg tagataagaa aacagtagat 66121 aagaaaacaa taaaaaacta ttacacaatt aaaaattgtt gtaatagttt tttatttaaa 66181 ctaatataac ttaaatttac taattataaa caatttaaac attaaacgtt gtcaggattt 66241 gagttctctt tatcaaattt attgcaaaaa tatagcaaga gtttcgttat aatataaaat 66301 aatattaaaa cggtaaatac tccagcaagt cctaacaaag ctacattgat accactggag 66361 aatacttccc aatttatttt cattaaaaat catccccttt ttacataaat agtggaacca 66421 gtgcaaggat cataccaccg gcaactattg aacctaattg tccggaaaca tttgcactaa 66481 tggattgtgc tattatgaag tttgtaggat cctccttggt agccaactgc tgaacaaccc 66541 tagcagacat tggaaatgcg gaaattcctg cagcaccgat cattgggttt atttttttct 66601 ttaagaacaa attcaatatt tttgcaaaaa ttactccgcc ggcagtgtca aatatgaaag 66661 caaccagtcc caaaccgata attaacaatg tacgcttatt aaggaattgc tctcctacca 66721 ttgttgaacc tattgtaata cccaaaagta tggttacaat attggcaagt tcgttttgag 66781 cggatttgga tagtctctcc agcacaccac attccctgat aaggtttcca aacattaaga 66841 atcctacaag ggcgacactg gatggtgcaa taagtccggc cagcaatgta actattatgg 66901 gaaacaaaat tttgactgac tttggtactt tttcctcggt gtattccatc cttataagtc 66961 tttctttttt agtggtgagg agtttgataa ccggaggttg aattatcgga accagagaca 67021 tgtaagaata tgcggctacg gtaatgggac cgataagacc cggagcaagt ttttgggcaa 67081 cgactatgga agtaggaccg tcagcagcac caatgatacc gattgtagca gcttcagcta 67141 aatcaaaacc gagtaaagtt gcaaccagca ttgtagcaaa aataccgaac tgggcggctg 67201 caccgaagaa caacataaac ggatttttga gtaatggacc gaaatcaatc atcgcaccta 67261 cggcgataaa aattaatacc ggaaaaagtt cagtctttat tcctgcgttg tataagatgc 67321 ttaatacacc ctcttcacct aaagcatttg aaaaaggtat gtttgccaga attgtgccga 67381 atccgatagg aagtaaaaga gttggttcat attctttcgc tattgcaagg taaataagta 67441 tacctgcaat aataaacatg gcaatgtttt gccaactcat acaaagtata cctttaagaa 67501 gctcttgcac aatgagtccc ccttattata atttttattc ccattaaagt atatttgttt 67561 tatgtcctta tttcaagtgg aattattata aatttaaaaa cggcgaaaaa gacagaaagt 67621 taacataatt caattttatt aaaaaaatga aattttttga taaaaagttg tttattcaat 67681 aaagagtgtt ggtagtatta attaaatatg tatttaaaat ataattaata tgtatattta 67741 tttaattaaa ctggtataag aggagggata taatttggac ggaaacacgc tggagttgat 67801 attcagttgt gcaaacagaa acttatgtga cggcaaaatc gaaaaggatg aaaaagaggg 67861 taagccggga aaaataaaat gttttaattg caataagaag ctatgcaggt tcagtaattt 67921 aacaaatacg gcaataatca aagaaaaagt tccaactatg aatataaaga aagatttaaa 67981 aaagccatat ccacttaaat taaaaaaatc cggaagaaag ctgcttgctg aaagatatta 68041 ccaaattctt agaagaaaat ataattgcct ttatgagatt tttaacagta ttgaacttcc 68101 gatagtaagt atatcctatc cgagttttaa tataattgga attaataata aagccaagaa 68161 agatgtaaag cttttgcgta aatgtgttgc atttgtaaga gaggttaaaa aaggtaataa 68221 tatattaaat gctttatcaa aagtatattc ttgtcgaaac caaaaatatt tagctgaaat 68281 gctttttaca aagtcgccgg tatatcttcc taatgttgaa attgataata atggcagaaa 68341 aatttattat aaattaatgc accagccgat tttaaattct cgtaataaaa tagtaggttt 68401 tctgataatt cccattgata taacccagga gatagaacag aaaaaatata tagaaaatct 68461 ggccagattc aaagatgagt ttttgtacgg cataacccat gagttcaaaa ctcctctggt 68521 agttataagc tcggctttgc aggcaataga ggctctttgc agagatgagc ttaccgacag 68581 ggtaaaaaaa tacttaaaca ggattaagca aaataccttc aggcaaataa ggcttgtaaa 68641 taatttgctg gatatagcca gaattgaggc cggtcatatc aaaatattca agaggaatct 68701 ggatattgtt gctttgactc gtctgataac cgagtcagta tcaatgtttg ccgatttaaa 68761 aggtgtacag ctcttgtttt attccaatat tgataaaaag attattgcta ttgatgaaga 68821 aaaatatgaa cggattatgc ttaacctgct ctcaaatgca attaaattta cccccaaaga 68881 tagatcggta tatgtggaag tttcagctaa ggagggatgt gtggagataa aagtcaaaga 68941 cagtggaata gggataccca aagataaaat caagaccatt tttgaaaggt tcgggcaggt 69001 ggacagttca ttgtcaagaa atgccgaggg tacaggtata ggattgtccc tggttcgcat 69061 gtttgtaaat gctatgggcg gagaaattag tgtgacgagc gaagaaaaca ttggcagtac 69121 ttttacagtc actttgcctg atgccgtaac tgaatgcgga tatgaaaatg actgttttga 69181 cgatttgaga gatgagcgtt tgatacaagc tatcaaaata gagttttcgg atatatattt 69241 tgaggaaaag gaagacaaaa agaaaagcct tgaaacttaa aacttcaagg cttttctttt 69301 tgtttggtgc gccatcaggg actcgaaccc cgggcccact gattaagagt cagttgctct 69361 accaactgag ctaatggcgc atatcttatt ttgtccgccg aacaattata tattataagg 69421 gggatgcatc atattgtcaa caccaaattt aaaaattttt ataaaatttt tgtccgtata 69481 gaataagtga taaattgtca aaaaattttt taagaaatag attgacattg ttatagatgt 69541 tgttgtataa tacatcttgc gtgattgatg aataacttgc cgaagtggtg aaattggcag 69601 acgcactgga ctcaaaatcc agcggtagca ataccatgcc ggttcgaatc cggccttcgg 69661 caccagataa aagaaaccaa ggatttcgat aatggaatcc ttgttt //