LOCUS NZ_ACVX01000019 68847 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00020, whole genome shotgun sequence. ACCESSION NZ_ACVX01000019 NZ_ACVX00000000 VERSION NZ_ACVX01000019.1 GI:256004829 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 68847) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 68847) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000019. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..68847 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene 116..2389 /locus_tag="ClothDRAFT_1665" CDS 116..2389 /locus_tag="ClothDRAFT_1665" /EC_number="3.1.13.1" /inference="protein motif:TFAM:TIGR02063" /note="KEGG: gsu:GSU1485 ribonuclease R, putative; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonuclease; PFAM: ribonuclease II; Ribonuclease B OB region domain; RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; Cold shock protein" /codon_start=1 /transl_table=11 /product="ribonuclease R" /protein_id="ZP_05429804.1" /db_xref="GI:256004830" /db_xref="InterPro:IPR001900" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR004476" /db_xref="InterPro:IPR011129" /db_xref="InterPro:IPR011805" /db_xref="InterPro:IPR013223" /translation="MMDRKERILAFMREDAYKPLLFSELVTVLDVPKSDIGLFENLLK ELEEEGLIFKNRKNRYGVPERMNLVCGYLQGNEHGYGFLIPDDENMKDIFIPSGGLNG AMHKDRVIARINKKGIGDKRAEGEIIKIVKRANKTVVGTFESSKYFGFVVPDDPRISG DIFIPKDEINGAKSGQKVVAEIVVWPEKRRNAEGRIIEIIGDKDEPGSDILSIIKAYN LREDFPEEVIREAKSISQTVTEDMIKGRRDLRDLTMVTIDGEDAKDLDDAVSIERLPN GNYRLGVHIADVSYYVKEGSPLDKEALKRGTSVYLVDRVIPMLPKELSNGICSLNPKV DRLAFTVMMEIDKSGRVVDHEIFESVINVNERMTYTDVYKILEENDEGLIERYKYLCD TFHTMKELALILRKKRMDRGAIDFNFDEAKIVLDEKGVPIEVKRYEMTIANNIIEEFM LVCNETVAEHFFWTNTPFVYRIHEDPDPDKIEAFSEFVHNLGYTLKGINKIHPKALQD VLEKARGTKEETIISTVMLRSLQKARYSHINSGHFGLAAKYYCHFTSPIRRYPDLIIH RIMKEYLKGTVNPEREDLLNSRLPEIAKLCSERERAAEEAERETEELKKVEFMKKHEG QVFEGIISNVTSFGMFVELENTIEGLVRISSLEDDYYVYNDKSYSLIGERSRKVYRIG DVVNVMLIKADVAARRIEFTIVDKNNGENDEKALESDGKENGKPKRKRRRKTPDEAVL LHVQGKKKKKKTKKAKV" misc_feature 119..2227 /locus_tag="ClothDRAFT_1665" /note="ribonuclease R; Region: RNase_R; TIGR02063" /db_xref="CDD:162678" misc_feature 326..505 /locus_tag="ClothDRAFT_1665" /note="S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain...; Region: S1_like; cl09927" /db_xref="CDD:186872" misc_feature 533..712 /locus_tag="ClothDRAFT_1665" /note="S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain...; Region: S1_like; cl09927" /db_xref="CDD:186872" misc_feature 851..1834 /locus_tag="ClothDRAFT_1665" /note="RNB domain; Region: RNB; pfam00773" /db_xref="CDD:144391" misc_feature 1985..2227 /locus_tag="ClothDRAFT_1665" /note="S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase play an...; Region: S1_RNase_R; cd04471" /db_xref="CDD:88436" misc_feature order(2009..2011,2033..2035,2063..2065,2069..2071) /locus_tag="ClothDRAFT_1665" /note="RNA binding site; other site" /db_xref="CDD:88436" gene 2464..2865 /locus_tag="ClothDRAFT_1666" CDS 2464..2865 /locus_tag="ClothDRAFT_1666" /inference="protein motif:PFAM:PF04463" /note="PFAM: protein of unknown function DUF523; KEGG: cvi:CV_4097 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF523" /protein_id="ZP_05429805.1" /db_xref="GI:256004831" /db_xref="InterPro:IPR007553" /translation="MNKKVMKLCSEETLIPVCPEQLGGCPTPRVPSEIADGDGADVLD GKSRVMNKNGEDVTEYFIKGAQEVLKIAKTMGIKKAILKARSPSCGFGSIYDGTFSGK TKRGNGVTSEILVRNGVSVLTEEDILTKEDI" misc_feature 2467..2847 /locus_tag="ClothDRAFT_1666" /note="Protein of unknown function (DUF523); Region: DUF523; cl00733" /db_xref="CDD:153961" gene complement(2995..3252) /locus_tag="ClothDRAFT_1667" CDS complement(2995..3252) /locus_tag="ClothDRAFT_1667" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429806.1" /db_xref="GI:256004832" /translation="MPKEHKGGNYMKSFNISLKSITDVKDFVNIVNKYDFDIDLTSGR YVVDAKSIMGIFSLDLSKPIRVDVHTDNCDEFCEEIKNFLV" misc_feature complement(3001..>3174) /locus_tag="ClothDRAFT_1667" /note="Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367" /db_xref="CDD:29444" misc_feature complement(order(3082..3087,3094..3105,3157..3159, 3166..3168)) /locus_tag="ClothDRAFT_1667" /note="regulatory protein interface; other site" /db_xref="CDD:29444" misc_feature complement(3100..3102) /locus_tag="ClothDRAFT_1667" /note="regulatory phosphorylation site; other site" /db_xref="CDD:29444" gene 3381..4685 /locus_tag="ClothDRAFT_1668" CDS 3381..4685 /locus_tag="ClothDRAFT_1668" /inference="protein motif:TFAM:TIGR00089" /note="KEGG: sat:SYN_00797 tRNA 2-methylthioadenosine synthase -like protein; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Protein of unknown function UPF0004 ; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB" /codon_start=1 /transl_table=11 /product="RNA modification enzyme, MiaB family" /protein_id="ZP_05429807.1" /db_xref="GI:256004833" /db_xref="InterPro:IPR002792" /db_xref="InterPro:IPR005839" /db_xref="InterPro:IPR006467" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013848" /translation="MKRAAFYTLGCKVNQYETEAISEMFEKAGYKIVDFEDEADVYVI NTCTVTNLSDRKSRQMIRRAKRNNENSIVIVIGCYAQTAPEEVSKIEGVNLVVGTKDR SRILEYLKELETSGGRRNYVGDIMKTREFEELGVNVYKERTRAFIKIQEGCNQFCTYC IIPYARGPVRSRSEENILKEVSGLAHSGYKEVVLTGIHVASYGKDIKNTSLIDIIRKV HEIEGIERIRLGSIEPTTVTEEFVRAIKGMEKLCPQFHISLQSGCDSTLKRMNRKYTT KEYLRSVELLRENLKDVAVTTDVMVGFPGETDEEFNETCRFVEKVLFARMHVFKYSRR KGTPAASYPDQVAPQKKEERSRILIELASRMTLEYNKSFTGRVLPVLFEQEVKGKEGF MEGLTPNYIRVECKGDKDIEGQILNVLLREAKDDYIVGEIVN" misc_feature 3387..4670 /locus_tag="ClothDRAFT_1668" /note="RNA modification enzyme, MiaB family; Region: TIGR00089" /db_xref="CDD:161701" misc_feature 3387..3674 /locus_tag="ClothDRAFT_1668" /note="Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919" /db_xref="CDD:144496" misc_feature 3819..4430 /locus_tag="ClothDRAFT_1668" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(3837..3839,3843..3845,3849..3851,3855..3863, 3963..3965,3987..3992,4068..4073,4077..4079,4146..4148, 4278..4280,4368..4373) /locus_tag="ClothDRAFT_1668" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene 4900..5172 /locus_tag="ClothDRAFT_1669" CDS 4900..5172 /locus_tag="ClothDRAFT_1669" /inference="protein motif:PFAM:PF06135" /note="PFAM: protein of unknown function DUF965" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF965" /protein_id="ZP_05429808.1" /db_xref="GI:256004834" /db_xref="InterPro:IPR009309" /translation="MSNNETMMFNVEKEKVNEARELLVSVYKALKEKGYNPINQIVGY ILSGDPTYITNHLDARSSIRKVERDELLEEILRCYLEECIGKEGSV" misc_feature 4900..5145 /locus_tag="ClothDRAFT_1669" /note="Bacterial protein of unknown function (DUF965); Region: DUF965; cl01857" /db_xref="CDD:186481" gene 5250..6197 /locus_tag="ClothDRAFT_1670" CDS 5250..6197 /locus_tag="ClothDRAFT_1670" /inference="protein motif:PFAM:PF00248" /note="PFAM: aldo/keto reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_2501 aldo/keto reductase" /codon_start=1 /transl_table=11 /product="aldo/keto reductase" /protein_id="ZP_05429809.1" /db_xref="GI:256004835" /db_xref="InterPro:IPR001395" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR017900" /translation="MKYCKLGNTGLEVSKLCFGGLIIGPLQANLPPETGAEIILKSFE LGVNFIDTAELYGTYSHIGKALKKTNKNIVVATKSYAYSAEGAKESLEKARKEMDIDV IDIFMLHEQESRLTLKGHREALEYYISMKEKGIIKAVGVSTHNVEVVEACCEMPEVDV IHPIVNKAGIGIGDGTIDDMLKAVEKAYSVGKGIYSMKPLGGGNLIKSYKEAMDFVLN IPYIHSIAVGMQSIEEVVMNVCIFEGKEVPQDVQKSLENKKRHLHIDWWCEGCGKCVE RCKQKALKLVDGKAKVEEEKCVLCSYCASVCPVFAIKVS" misc_feature 5256..6020 /locus_tag="ClothDRAFT_1670" /note="Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and...; Region: Aldo_ket_red; cd06660" /db_xref="CDD:119408" misc_feature order(5304..5312,5400..5402,5415..5417,5481..5483, 5574..5579,5673..5678,5733..5735,5838..5855,5925..5936, 5949..5951,5958..5963) /locus_tag="ClothDRAFT_1670" /note="active site" /db_xref="CDD:119408" misc_feature order(5400..5402,5415..5417,5481..5483,5574..5576) /locus_tag="ClothDRAFT_1670" /note="catalytic tetrad; other site" /db_xref="CDD:119408" misc_feature <6036..6194 /locus_tag="ClothDRAFT_1670" /note="RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409" /db_xref="CDD:187025" gene 6319..6744 /locus_tag="ClothDRAFT_1671" CDS 6319..6744 /locus_tag="ClothDRAFT_1671" /inference="protein motif:PFAM:PF03652" /note="PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; KEGG: sat:SYN_01734 4-amino-4-deoxychorismate lyase" /codon_start=1 /transl_table=11 /product="Holliday junction resolvase YqgF" /protein_id="ZP_05429810.1" /db_xref="GI:256004836" /db_xref="InterPro:IPR005227" /db_xref="InterPro:IPR006641" /translation="MRVLGIDYGDSRIGIAISDPLGWTAQALETITWRSDVEVPLKRI SELVEEYGVKTVIVGFPKNMDGTVGARGEKTIEFIDLLQQRIKDIEVIKWDERLTTVA ANRTMYEMGIKKSKKKLVVDQIAAVYILQGYLDSKGKVL" misc_feature 6319..6729 /locus_tag="ClothDRAFT_1671" /note="Uncharacterized protein family (UPF0081); Region: UPF0081; cl00525" /db_xref="CDD:186059" gene 6847..7137 /locus_tag="ClothDRAFT_1672" CDS 6847..7137 /locus_tag="ClothDRAFT_1672" /inference="protein motif:PFAM:PF06949" /note="PFAM: protein of unknown function DUF1292; KEGG: mature-parasite-infected erythrocyte surface antigen" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1292" /protein_id="ZP_05429811.1" /db_xref="GI:256004837" /db_xref="InterPro:IPR009711" /translation="MSEERDDLVVLIDENGEETEFEHLDTIEYNGNEYVVLLPVEQTE EENDAEEVVILRIEQGEDGEDSFVTVEDDEELDAVFEEFKMRMEEEFEFEEE" misc_feature 6886..7083 /locus_tag="ClothDRAFT_1672" /note="Protein of unknown function (DUF1292); Region: DUF1292; cl01608" /db_xref="CDD:141269" gene 7307..8368 /locus_tag="ClothDRAFT_1673" CDS 7307..8368 /locus_tag="ClothDRAFT_1673" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429812.1" /db_xref="GI:256004838" /translation="MYHNFSIKKAVLLLGILALVMFSVSCGRSDNTENNPDASPEPTE ENVNFDYVEQPSPEPEQEVNFVFPEKGVRPYAVMIDNQGEKCLPQGGLSQAQVIYEVI VEGGITRFMPVFWGQKTELIGPVRSARHYFLDYALEHDAIYVHIGWSPMAMADIPKLG VNNINGAYGVFWDITNDKSNWQDTYTSMEKLEEYAKKVNYRTTTDKEMVFKYHNRDQE LEGGKKAEKINLSYSGEYKSYYEYDADKKLYLRFRNGKPHIERQTGEQLTTKNIIIQK VRNYDIKGDQYGRQNLDTVGSGEGYYITNGKCIEIKWSKASRTEKTKYLDGDGKEIVL NPGQTWVQIFPVSGKIEIE" sig_peptide 7307..7390 /locus_tag="ClothDRAFT_1673" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.544 at residue 28" misc_feature 7523..8329 /locus_tag="ClothDRAFT_1673" /note="Protein of unknown function (DUF3048); Region: DUF3048; pfam11258" /db_xref="CDD:151699" gene 8607..10448 /locus_tag="ClothDRAFT_1674" CDS 8607..10448 /locus_tag="ClothDRAFT_1674" /inference="protein motif:PFAM:PF04055" /note="PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gur:Gura_0300 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="Radical SAM domain protein" /protein_id="ZP_05429813.1" /db_xref="GI:256004839" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /translation="MGIRVSDRILQSVEKPSRYTGNEWNSVKKDLKGIDIRFAFCFPD VYEVGMSHLGMKILYHLLNEREDTYCERVFAPWVDMEAKMREHNIPLFALETHDPIRE FDFIGFTLQYEMSYTNIINMLDLAGVPVLSGERTKEHPFVCAGGPCAYNPEPLADFID FFMMGEGEEIINEVMDVYVQWKKKNLPREEFLRCISSIEGVYVPQFYDVKYNDDGTIS SFLPIRDEYPKKIRKRIIKDLDKVFFPEKIVVPFTGIVHDRIMVELFRGCIRGCRFCQ AGFIYRPVRERSADRLLEISRKLEESTGYEEISLTSLSTSDYTALKELTDGLICEMEP KKVNLSLPSLRVDSFSLELMEKAQKVRKSGLTFAPEAGTQRLRNVINKGVTEEDLIKS VSLAFEGGWSGVKLYFMLGLPTESYEDIEGIAELGHKVVEAYKNTPKDKKGKGLSVTI STSSFVPKPFTPFQWEPQDSIETLREKQIFLKSKIKSKSIKYNWHDPELSFLEAIFAR GDRKLGKVLLKAFEKGCKFDSWGEHFKFDKWMEAFRECGIDPSFYANRKRSYGEILPW DHIDVGVSKKFLEREHEKALKEEVTPNCRANCSGCGATVFEGGICVE" misc_feature 8712..10259 /locus_tag="ClothDRAFT_1674" /note="Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032" /db_xref="CDD:31235" misc_feature 9390..9896 /locus_tag="ClothDRAFT_1674" /note="Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster...; Region: Radical_SAM; cd01335" /db_xref="CDD:100105" misc_feature order(9408..9410,9414..9416,9420..9422,9426..9434, 9537..9539,9543..9548,9624..9629,9708..9710,9831..9833) /locus_tag="ClothDRAFT_1674" /note="FeS/SAM binding site; other site" /db_xref="CDD:100105" gene 10438..11277 /locus_tag="ClothDRAFT_1675" CDS 10438..11277 /locus_tag="ClothDRAFT_1675" /inference="protein motif:COG:COG5011" /note="KEGG: gur:Gura_0300 radical SAM domain-containing protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429814.1" /db_xref="GI:256004840" /translation="MLSSIRVKFVRGEEVKYISHLDLMKMFERAVRRSNIPIAYSQGF NPHPHIVFGLPLSVGVTSDSEYADFELEKDMKPEEFAQRLNQNLPEGVKIVEAKKNNT NSNIMAQVAGALYEVLVLADGKVEIEDLKSKLSKFLENKEIFTEKESKGKIKSVDIRP MIYNVAVTTVKNTEAGVLESTKTDFTEDGCKNLWILKYVEKLKAEDDLFKQTDESAVF CFTMLLAAGSMANLKPEFVIAAFGRYSGINFEILKIHRSGLFTKNKDNLTDPLGGRVL LSV" misc_feature 10450..10956 /locus_tag="ClothDRAFT_1675" /note="Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; cl02090" /db_xref="CDD:154738" gene 11309..12781 /locus_tag="ClothDRAFT_1676" CDS 11309..12781 /locus_tag="ClothDRAFT_1676" /inference="protein motif:TFAM:TIGR00757" /note="KEGG: gbm:Gbem_0159 ribonuclease, Rne/Rng family; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein" /codon_start=1 /transl_table=11 /product="ribonuclease, Rne/Rng family" /protein_id="ZP_05429815.1" /db_xref="GI:256004841" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR004659" /translation="MWGLMKKEWLLLEDRELVELFIERNDCERLVGNIYRGRVESVLP GMQAAFIDIGYEKNAFLYVGDAIPQKEFSEDDEEIYSDVKSYNIEEILRPGQEITVQV TKEPIGTKGPRVTTHITLPGRQMVLLPNADYIGISRRIEDEEERAKLRKIAEKIKPKN MGIIVRTVSEGKREEDFKNDLNFLVKLWAKIKQREQSGPVPRCLHKDLSVIYRAVRDI FTWNIDRFVINDRQEYNKVLELVEMISPALKMRVEYFNKNIDLFEYYQIDSMIQKALA KKVWLKCGGYIVIERTEALTVIDVNTGKYVGVNNLEDTVLRTNLDAVKEIGKQLRLRD IGGIIIIDFIDMHDPEHQKQVLEALKQVLKKDRTKTTVVGMTGLGLIEMTRKKVREGL ESMMLQDCPYCEGRGKILSPESVARNVEKEISKYFTKTIANAIMVEVHPTVAEVLRGE DNDNLARIQNLFNKKVIIKPSAEVGHEEVKIKEVDIDTLV" misc_feature 11339..12571 /locus_tag="ClothDRAFT_1676" /note="ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757" /db_xref="CDD:162024" misc_feature 11390..11677 /locus_tag="ClothDRAFT_1676" /note="S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453" /db_xref="CDD:88419" misc_feature order(11414..11416,11585..11587,11597..11599) /locus_tag="ClothDRAFT_1676" /note="homodimer interface; other site" /db_xref="CDD:88419" misc_feature order(11486..11488,11618..11620,11627..11629,11636..11641, 11669..11671) /locus_tag="ClothDRAFT_1676" /note="oligonucleotide binding site; other site" /db_xref="CDD:88419" gene 12888..13199 /locus_tag="ClothDRAFT_1677" CDS 12888..13199 /locus_tag="ClothDRAFT_1677" /inference="protein motif:TFAM:TIGR00061" /note="TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: mfa:Mfla_2219 50S ribosomal protein L21P" /codon_start=1 /transl_table=11 /product="ribosomal protein L21" /protein_id="ZP_05429816.1" /db_xref="GI:256004842" /db_xref="InterPro:IPR001787" /translation="MYAVIETGGKQYKVQEGDVLFIEKLANEEGSTVTFDKVVAVSKD DKVSFGTPFVSNASVTAKVLCHGKGKKIIVFKYKPKKGYRRKQGHRQPYTKIQIEKIN A" misc_feature 12888..13196 /locus_tag="ClothDRAFT_1677" /note="Ribosomal prokaryotic L21 protein; Region: Ribosomal_L21p; cl00382" /db_xref="CDD:185955" gene 13212..13553 /locus_tag="ClothDRAFT_1678" CDS 13212..13553 /locus_tag="ClothDRAFT_1678" /inference="protein motif:PFAM:PF04327" /note="PFAM: protein of unknown function DUF464" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF464" /protein_id="ZP_05429817.1" /db_xref="GI:256004843" /db_xref="InterPro:IPR007422" /translation="MIKVEVIRDSERFIRELKIKGHAGYGRSGKDIVCAAVSALAYTA AGALEELAGIKGYNERNGYMRCTVPKDIPEDKKEMVRTILETVVIGLKQVELGYGKYV SVLDKEVLTDD" misc_feature 13212..13538 /locus_tag="ClothDRAFT_1678" /note="Protein of unknown function (DUF464); Region: DUF464; cl01080" /db_xref="CDD:186323" gene 13546..13824 /locus_tag="ClothDRAFT_1679" CDS 13546..13824 /locus_tag="ClothDRAFT_1679" /inference="protein motif:TFAM:TIGR00062" /note="TIGRFAM: ribosomal protein L27; PFAM: ribosomal protein L27; KEGG: gsu:GSU3235 50S ribosomal protein L27" /codon_start=1 /transl_table=11 /product="ribosomal protein L27" /protein_id="ZP_05429818.1" /db_xref="GI:256004844" /db_xref="InterPro:IPR001684" /translation="MIKANLQLFAHKKGVGSTRNGRDSESKRLGVKRGDGQFVKAGNI LVRQRGTKIHPGLNVGKGKDDTLFALVDGRVKFSRLGKDRKQVSIIPA" misc_feature 13570..13815 /locus_tag="ClothDRAFT_1679" /note="Ribosomal L27 protein; Region: Ribosomal_L27; cl00359" /db_xref="CDD:185938" gene 13933..15207 /locus_tag="ClothDRAFT_1680" CDS 13933..15207 /locus_tag="ClothDRAFT_1680" /inference="protein motif:TFAM:TIGR02729" /note="TIGRFAM: GTP-binding protein Obg/CgtA; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; GTP1/OBG domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="GTP-binding protein Obg/CgtA" /protein_id="ZP_05429819.1" /db_xref="GI:256004845" /db_xref="InterPro:IPR002917" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR006074" /db_xref="InterPro:IPR006169" /db_xref="InterPro:IPR014100" /db_xref="InterPro:IPR015349" /translation="MFVDRARIYIKAGDGGDGAISFHREKYISKGGPDGGDGGKGGDV IFVVDEGLRTLQDFRYKTRYRAEDGQNGGSSNCSGRSGEDLIIKVPPGTLVKDEQTGR ILADLVKPGKKVVIAKGGKGGAGNQHFATPTRQVPSFAKPGEPGEELWVILELKLLAD VGLIGFPNVGKSTILSMVTAAQPKIANYHFTTINPNLGVVNIDAENAFVMADIPGLIE GAHQGVGLGHEFLKHIERTKLLIHVVDISGSEGRDPVQDFEVINEELKKYNPVLCERP QIIAANKMDVTGAEENLEKFRKVIEPRGYKIFPVSAASNKGLKELIYYAAQKLKELPD TVLVNDQDNEVVYTAVEEEPFNIRKENGVFVVEGSWVQRLVRSVNFDNYESLQYFQRA IRRKGIVDALESMGINEGDTVRMYDLEFEYFR" misc_feature 13933..15201 /locus_tag="ClothDRAFT_1680" /note="GTPase CgtA; Reviewed; Region: obgE; PRK12297" /db_xref="CDD:183415" misc_feature 13936..14403 /locus_tag="ClothDRAFT_1680" /note="GTP1/OBG; Region: GTP1_OBG; pfam01018" /db_xref="CDD:110047" misc_feature 14407..14919 /locus_tag="ClothDRAFT_1680" /note="Obg subfamily. The Obg nucleotide binding protein subfamily has been implicated in stress response, chromosome partitioning, replication initiation, mycelium development, and sporulation. Obg proteins are among a large group of GTP binding proteins...; Region: Obg; cd01898" /db_xref="CDD:133298" misc_feature 14425..14448 /locus_tag="ClothDRAFT_1680" /note="G1 box; other site" /db_xref="CDD:133298" misc_feature order(14434..14451,14776..14781,14785..14787,14863..14868) /locus_tag="ClothDRAFT_1680" /note="GTP/Mg2+ binding site; other site" /db_xref="CDD:133298" misc_feature 14470..14517 /locus_tag="ClothDRAFT_1680" /note="Switch I region; other site" /db_xref="CDD:133298" misc_feature 14506..14508 /locus_tag="ClothDRAFT_1680" /note="G2 box; other site" /db_xref="CDD:133298" misc_feature 14566..14577 /locus_tag="ClothDRAFT_1680" /note="G3 box; other site" /db_xref="CDD:133298" misc_feature order(14575..14598,14605..14643) /locus_tag="ClothDRAFT_1680" /note="Switch II region; other site" /db_xref="CDD:133298" misc_feature 14776..14787 /locus_tag="ClothDRAFT_1680" /note="G4 box; other site" /db_xref="CDD:133298" misc_feature 14863..14871 /locus_tag="ClothDRAFT_1680" /note="G5 box; other site" /db_xref="CDD:133298" misc_feature 15001..15198 /locus_tag="ClothDRAFT_1680" /note="Domain of unknown function (DUF1967); Region: DUF1967; cl07779" /db_xref="CDD:164101" gene 15639..15929 /locus_tag="ClothDRAFT_1681" CDS 15639..15929 /locus_tag="ClothDRAFT_1681" /inference="protein motif:PFAM:PF01985" /note="PFAM: protein of unknown function UPF0044; KEGG: gsu:GSU1263 hypothetical protein" /codon_start=1 /transl_table=11 /product="protein of unknown function UPF0044" /protein_id="ZP_05429820.1" /db_xref="GI:256004846" /db_xref="InterPro:IPR001890" /db_xref="InterPro:IPR017924" /translation="MLTGKQRSYLRSLANSIEPIFQIGKGGINDNMIKQFNEALEARE LIKVAVLKNAMVDTKEVCHEVASLVGAEVVQVIGNKFVLYKESKENKVIELP" misc_feature 15639..15926 /locus_tag="ClothDRAFT_1681" /note="CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663" /db_xref="CDD:186133" gene complement(16015..16572) /locus_tag="ClothDRAFT_1682" CDS complement(16015..16572) /locus_tag="ClothDRAFT_1682" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: conserved hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429821.1" /db_xref="GI:256004847" /translation="MSIVSNKELAENKLILLYIIDKVNIPISNLQITKIILENKFMNY FMLQQLLNELCTSNYLLYKNIDNKAFYTITPLGKQTLSYFTGHIPQGIKSLIDNSISN IRNNIRNETFISAEYTLSGENEFTVSCQVREDNFNLIDLKVTVGTKNDARRICENWKK HSQEIYSEIIESLIKDRIKNTGENS" gene 16880..17560 /locus_tag="ClothDRAFT_1683" CDS 16880..17560 /locus_tag="ClothDRAFT_1683" /inference="protein motif:PFAM:PF00037" /note="PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvm:DvMF_1046 4Fe-4S ferredoxin iron-sulfur binding domain protein" /codon_start=1 /transl_table=11 /product="4Fe-4S ferredoxin iron-sulfur binding domain protein" /protein_id="ZP_05429822.1" /db_xref="GI:256004848" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR017900" /translation="MNNFTKIQDKLMEMGASFVGCSDVEAYLPENLKKVKYAITVGVR LSDFIIDQISDKPTYTYFHHYRAVNTLIDQITLRGQIEIQNMGYSAMAVPASQTVNDL EDRYSGVFQHKTAAVKAGLGWIGKNGLFISTKYGPRVRLGTILTDMELPIGSHVVRDG CGSCRICVDSCPAMALTGNSWFAGCDRSHIVDAQACSEYMNRNFKHIGRGSVCGICIR VCPKGFSK" misc_feature 16883..>17548 /locus_tag="ClothDRAFT_1683" /note="Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600" /db_xref="CDD:31788" gene 17598..17966 /locus_tag="ClothDRAFT_1684" CDS 17598..17966 /locus_tag="ClothDRAFT_1684" /inference="protein motif:PFAM:PF00072" /note="PFAM: response regulator receiver; KEGG: vvy:VV0056 response regulator" /codon_start=1 /transl_table=11 /product="response regulator receiver protein" /protein_id="ZP_05429823.1" /db_xref="GI:256004849" /db_xref="InterPro:IPR001789" /translation="MKKVLLVNDSKFESMILKDMLVSIGYIAGIADEYDAIEKVQDMR PDYIIINRVMKEIYGDELASKIKARFPEIKCILSSCDSISIDDYKNSGIDAVIRTPVD QYRLKAVLKNVEYLKNDIRK" misc_feature 17607..>17813 /locus_tag="ClothDRAFT_1684" /note="Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems...; Region: REC; cl09944" /db_xref="CDD:175054" gene 18019..18489 /locus_tag="ClothDRAFT_1685" CDS 18019..18489 /locus_tag="ClothDRAFT_1685" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429824.1" /db_xref="GI:256004850" /translation="MGYVFFYLSLFGVLISLIICLYFKPLDFRKAVIGIMTVAYSMIY ETVLSGYLSLYYYLNPRDSVIYIVMSAILLYPSLNIMYTMFLPKDKKAVLGYTIAWMA AMMIFEYFSVMFGTVVFTGWTPFPWSVVTYVVTYLWVYLTYRYLSKKRLTGKLL" gene complement(18501..19583) /locus_tag="ClothDRAFT_1686" CDS complement(18501..19583) /locus_tag="ClothDRAFT_1686" /inference="protein motif:COG:COG0644" /note="KEGG: kpe:KPK_1335 AegA protein" /codon_start=1 /transl_table=11 /product="Dehydrogenase (flavoprotein)-like protein" /protein_id="ZP_05429825.1" /db_xref="GI:256004851" /db_xref="InterPro:IPR003042" /translation="MKVAIIGGGLSGLSCAHELERHGISPVIFHRNGYIGDQYSHISV LLEIQHRPIKDAIKYIKKNFDISITPVNTVNTLTHYSPNRKTVIKGNFGFFLKRGRDK DSLPMQLFSHLKTSKINFNTYGDIDPLAKEFDYVVVANGNTVFTNQLGCWYPTIKTYI RGAVLLGDFDPNNLIMWINKDYCKNGYAYLSPFNSKKASVILVVTDVNEKEIDHYWKA FLDYENINYTIVEEFKQAHDTGFAYPHKVDNIYFVGNAGGAIDPFLGFGQLNSIEMGV MAARSIANGDDYERLLKRVTKHNQQLYQMRKAFNTADNDTYDSLLASIGFPGIRHLLY NTRFDVVKNFARIYRLKEKLENRKKQ" misc_feature complement(18531..19583) /locus_tag="ClothDRAFT_1686" /note="Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644" /db_xref="CDD:30989" misc_feature complement(<19476..19580) /locus_tag="ClothDRAFT_1686" /note="Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; cl14644" /db_xref="CDD:187400" gene complement(19585..19677) /locus_tag="ClothDRAFT_1687" CDS complement(19585..19677) /locus_tag="ClothDRAFT_1687" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429826.1" /db_xref="GI:256004852" /translation="MNIFLYTVLTFANGLLVSAWLIFLKRFGGI" gene complement(19674..20126) /locus_tag="ClothDRAFT_1688" CDS complement(19674..20126) /locus_tag="ClothDRAFT_1688" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429827.1" /db_xref="GI:256004853" /translation="MEWVILFVMSWIIFFVFIDFRQLKRNIWGGILAAVLQLVTDTQA INQGLYTVNEPVISIMGSSLFFTAGPVFTVGTLFSQLHPKKRWLRIVNIFAISALFFL QEILLILSGNLAYTNWHFTSSLFINVCVMIVLSWFSIVVLDKKEDVAR" gene complement(20173..20412) /locus_tag="ClothDRAFT_1689" CDS complement(20173..20412) /locus_tag="ClothDRAFT_1689" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429828.1" /db_xref="GI:256004854" /translation="MVIYLEQSAILQDLLQSKIANEMFYNECLIYIKNPEARQVFTQL RDDEMRDIVNLQQKIDRIQSSEGIISKLFPLKPRI" gene complement(20439..20654) /locus_tag="ClothDRAFT_1690" CDS complement(20439..20654) /locus_tag="ClothDRAFT_1690" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429829.1" /db_xref="GI:256004855" /translation="MERQSQQYILNIAFTGAINREELLLKKYEHYYQITKDKELKNIL RDFSQTSRDHIKMINDKMILLSIDKSQ" gene 20822..21916 /locus_tag="ClothDRAFT_1691" CDS 20822..21916 /locus_tag="ClothDRAFT_1691" /inference="protein motif:COG:COG0644" /note="KEGG: pcr:Pcryo_2164 glutamate synthase subunit beta" /codon_start=1 /transl_table=11 /product="Dehydrogenase (flavoprotein)-like protein" /protein_id="ZP_05429830.1" /db_xref="GI:256004856" /db_xref="InterPro:IPR003042" /db_xref="InterPro:IPR013027" /translation="MKIAIIGAGLAGLSCAFELERNGITPVIFEKRSFIGENYMFPST TLRLFDRGFNNPVKYLKKKYDLSLIPFSPLREITMKGPTKEGTVSGKLGYVFMRGDEK ESLENQIAKHIRTPMHFDTYINLEDVKNDFDYIIVATGDETVANRLGVWHTTTTVYTR VALVLGNFKVGCAKMWVNRDYDKACYAFLSPHSKKSARLLLSVNDISPHEFDYYWNNF VRLEEVKYKINETRDIVTRLGYVSTAKVGNVYLTGNAAGLIDDFLGFGAINAIESGIL AAKAIIKGKDYNEMVKSIKNHVAGIHELRKMINEFDNDDYDRLIKILTMPVIKRIIYN NPLAKVQSITSAAKEFNNMKHKRQRRFSKS" misc_feature 20822..21817 /locus_tag="ClothDRAFT_1691" /note="Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644" /db_xref="CDD:30989" sig_peptide 20822..20872 /locus_tag="ClothDRAFT_1691" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.606) with cleavage site probability 0.478 at residue 17" misc_feature 20825..>20929 /locus_tag="ClothDRAFT_1691" /note="Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; cl14644" /db_xref="CDD:187400" gene 22098..23990 /locus_tag="ClothDRAFT_1692" CDS 22098..23990 /locus_tag="ClothDRAFT_1692" /inference="protein motif:PFAM:PF00884" /note="PFAM: sulfatase; KEGG: afw:Anae109_1028 sulfatase" /codon_start=1 /transl_table=11 /product="sulfatase" /protein_id="ZP_05429831.1" /db_xref="GI:256004857" /db_xref="InterPro:IPR000917" /translation="MKISIERARSNIFTNTRPQLDVFGIIYTVLFVCSIVFKGVFLQF QNQINFKPLFSTTNIFMFVASMSFTLVLAALLTVFHTKRRVLFFISNILMSVLLLSDA LYLRYYNTIITIPVIYNARYLGPVRESIMSLFRFSDIFYFLDIPVFAVMSFIFSKRAE QNKLPLLKRCVVAAVLMVVAFGSFKIAYSKNDMSEYDNNYIVKNFGIGYFHYYDVKKY LKENYLRDKKLRTEEKNELTSFFEEKNKEKAALSNRFKGIAKGKNLIIVQMEALQHFV INSKMNGREITPNLNKLVKESLYFDNIYVQVAGGNTSDAEFMTNTSLYPAKEGAAYFR FATNEYNTIPKELKKEGYNSYALHAYGPAFWNRTEMYKAIGFDTFISSNDYVMDEYIG WGGWALSDDSFFRQSLEKIDVTKPFYSFFITLSGHHPYSYFEDKQTFDVGKYDRTYFG NYIKAQNYADAALGRFIERLKEMGLYENSLIVIYGDHTGLPKTQAKELLEFLGVDDNK VDWIKLQKIPLLIHCPGVKGETISTTGGQVDIFPMIANMMGFENYYALGKDLLNTEKG YAVLRNGSVLTDDYYYCSEDDTVYDLRSGEVLDKKDYEDEIQKYQKELQISDIILEKD ALRKLK" misc_feature 22155..23978 /locus_tag="ClothDRAFT_1692" /note="Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368" /db_xref="CDD:31559" misc_feature 22881..23795 /locus_tag="ClothDRAFT_1692" /note="Sulfatase; Region: Sulfatase; cl10460" /db_xref="CDD:186998" gene 24174..25310 /locus_tag="ClothDRAFT_1693" CDS 24174..25310 /locus_tag="ClothDRAFT_1693" /inference="protein motif:PFAM:PF01522" /note="PFAM: polysaccharide deacetylase; KEGG: mno:Mnod_3023 polysaccharide deacetylase" /codon_start=1 /transl_table=11 /product="polysaccharide deacetylase" /protein_id="ZP_05429832.1" /db_xref="GI:256004858" /db_xref="InterPro:IPR002509" /translation="MASFFKSRVARILPLIALSLSLLFAGCNTSPKLNGDLKSPVPNT AGQDAGQEGGSLATPTPTPTPEPTPTIDLQSVKPNEAGKIMVVMFHNFVESFTPKSYD KGEYTTTFSEFEKLLQDLYDRGYRLISMSDYLNNNISVPAGCIPIIFTFDDGTSGQFN LVEENGTLKVNKKSAVGIMEEFYEKHPDFGLKGTFYVNLGNSTFEGAGTLQQRLQYLV DKGFEIGNHTYTHINLKDTTSAQKIQEEIAKNQRTIAELIPGYKMTTFSLPYGLPSVE GLHSYVIKGSYEGVEYEHAAIMEVGWDPAHSPVSKDFNPLSTHRVRASGINPVDCDLA WWLKNLSREEQYISDGDPNTVTVPKKNEDKVDKDKLKDKKLVIY" sig_peptide 24174..24263 /locus_tag="ClothDRAFT_1693" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.935) with cleavage site probability 0.641 at residue 30" misc_feature 24612..24986 /locus_tag="ClothDRAFT_1693" /note="Polysaccharide deacetylase; Region: Polysacc_deac_1; cl12061" /db_xref="CDD:164326" gene 25591..25941 /locus_tag="ClothDRAFT_1694" CDS 25591..25941 /locus_tag="ClothDRAFT_1694" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: KIF3C; kinesin family member 3C ; K10394 kinesin family member 3/17" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429833.1" /db_xref="GI:256004859" /translation="MEKVQSNANSKKEGTKKEGRKVQTDADVKKKAVKLVISHLKKKI AKEFSGSELVRQWVEEMEKLLEKEEFELAEYMRMRRELNDIIERIMDEEMRFKLRDSW YSFGRALDKKVKKY" gene 26112..26309 /locus_tag="ClothDRAFT_1695" CDS 26112..26309 /locus_tag="ClothDRAFT_1695" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429834.1" /db_xref="GI:256004860" /translation="MFTLLKRKFDESYNSRQIGKIRKDLIESLKKMGVEVSNIQIDLE ENNVSLRLSIPRKKYGSVPNE" gene complement(26435..27811) /locus_tag="ClothDRAFT_1696" CDS complement(26435..27811) /locus_tag="ClothDRAFT_1696" /inference="protein motif:TFAM:TIGR00838" /note="TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: gur:Gura_0231 argininosuccinate lyase" /codon_start=1 /transl_table=11 /product="argininosuccinate lyase" /protein_id="ZP_05429835.1" /db_xref="GI:256004861" /db_xref="InterPro:IPR000362" /db_xref="InterPro:IPR003031" /db_xref="InterPro:IPR009049" /translation="MKLWGGRFEKNTDKSVDDFNSSIRFDCRMYKQDILGSIAHAKML GKCKIISEEDSILIQNTLREILKDIEEGKVQFEIDAEDIHMNVEKILISRIGDVGKKL HTGRSRNDQVALDIRMYLRDEVVEIRKLLVNLERTLIEIAKNNIDTILPGYTHLQRAQ PITFAHHMMAYFQMFKRDIERLNDCYKRINVMPLGSGALASTTYPLDRYMVAKELGFD SITENSLDAVSDRDFVIELSACLSILMMHLSRFSEEIILWASHEFGFIELDDAYSTGS SIMPQKKNPDVAELVRGKTGRVYGDLMALLSVMKSLPLAYNKDMQEDKEAIFDAVDTV KMCLPVFTKMIETMKIKKENMLRAAQGGFTNATDMADYLVKKGIPFRNAHEIIGKMVL YCIENNKAIEELDMSEFKSFSELIEEDVYEEISLSKCVSGRNLPGGPAKESVMASIEN GLKFLSTQ" misc_feature complement(26444..27811) /locus_tag="ClothDRAFT_1696" /note="argininosuccinate lyase; Provisional; Region: PRK00855" /db_xref="CDD:179143" misc_feature complement(26447..27748) /locus_tag="ClothDRAFT_1696" /note="Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359" /db_xref="CDD:176463" misc_feature complement(order(26840..26845,26849..26851,26858..26860, 26864..26866,26945..26947,26954..26956,26960..26962, 26984..26986,26990..26992,27119..27121,27347..27352, 27476..27478,27485..27493,27560..27562,27566..27568, 27734..27736,27746..27748)) /locus_tag="ClothDRAFT_1696" /note="active sites" /db_xref="CDD:176463" misc_feature complement(order(26471..26473,26495..26509,26513..26515, 26651..26653,26660..26662,26669..26674,26687..26689, 26699..26701,26714..26716,26795..26797,26804..26806, 26837..26839,26846..26848,26855..26866,26888..26896, 26900..26902,26909..26917,26921..26938,26942..26947, 26954..26956,26960..26968,26972..26983,26999..27001, 27023..27025,27032..27037,27050..27055,27062..27067, 27071..27076,27083..27085,27095..27097,27104..27106, 27116..27118,27122..27127,27134..27148,27188..27190, 27197..27199,27203..27217,27248..27250,27260..27262, 27269..27274,27281..27283,27299..27304,27314..27316, 27332..27355,27500..27505,27512..27514,27521..27523)) /locus_tag="ClothDRAFT_1696" /note="tetramer interface; other site" /db_xref="CDD:176463" gene complement(27821..29038) /locus_tag="ClothDRAFT_1697" CDS complement(27821..29038) /locus_tag="ClothDRAFT_1697" /EC_number="6.3.4.5" /inference="protein motif:TFAM:TIGR00032" /note="KEGG: argininosuccinate synthase; K01940 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase" /codon_start=1 /transl_table=11 /product="argininosuccinate synthase" /protein_id="ZP_05429836.1" /db_xref="GI:256004862" /db_xref="InterPro:IPR001518" /translation="MSQKEKVILAYSGGLDTSIIIPWLKENYDYEVIAMAADVGQGEE LEPLREKAIKTGASKIYIEDLKEEFVTDFIFPTLKAGAVYEGKYLLGTSFARPLIAKR MVEIALKEGATAVAHGATGKGNDQVRFELTVKALAPHLKIIAPWRIWDIKSREDEIEY AQARNIPIPVSKEDNYSMDRNLWHLSHEGLDLEDPWNEPQYDKILKLMVPPEKAPDKP TYVEIYFEKGIPKKVNGVEYGPVELIEVLNKIGGENGIGIVDIVENRLVGMKSRGVYE TPGGTILYAAHRELELLCLDRDTLHYKDLVAQRFAELVYYGQWYTPLREAISAFVDVT QETVTGTVRLKLYKGNIISAGAKSDYSLYSEELSTFGEDNVYNQKDAEGFINLFGLPM KVQALMKEKNKGK" misc_feature complement(27836..29038) /locus_tag="ClothDRAFT_1697" /note="argininosuccinate synthase; Provisional; Region: PLN00200" /db_xref="CDD:177791" misc_feature complement(27866..29020) /locus_tag="ClothDRAFT_1697" /note="Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate . In...; Region: Argininosuccinate_Synthase; cd01999" /db_xref="CDD:30186" misc_feature complement(order(28505..28510,28652..28654,28685..28687, 28751..28753,28916..28918,28928..28930,28934..28936, 28988..28990,29009..29011)) /locus_tag="ClothDRAFT_1697" /note="ANP binding site; other site" /db_xref="CDD:30186" misc_feature complement(order(28094..28096,28214..28216,28250..28252, 28475..28477,28481..28483,28502..28510,28655..28657, 28667..28669,28760..28765,28775..28777)) /locus_tag="ClothDRAFT_1697" /note="Substrate Binding Site II; other site" /db_xref="CDD:30186" misc_feature complement(order(28664..28672,28679..28684)) /locus_tag="ClothDRAFT_1697" /note="Substrate Binding Site I; other site" /db_xref="CDD:30186" gene 29274..29762 /locus_tag="ClothDRAFT_1698" CDS 29274..29762 /locus_tag="ClothDRAFT_1698" /EC_number="3.1.22.4" /inference="protein motif:TFAM:TIGR00228" /note="KEGG: geo:Geob_2325 crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC" /codon_start=1 /transl_table=11 /product="crossover junction endodeoxyribonuclease RuvC" /protein_id="ZP_05429837.1" /db_xref="GI:256004863" /db_xref="InterPro:IPR002176" /translation="MIIMGIDPGFAIAGYGIVKYEGNKFTSVDYGAITTESSMELPKR LLVLYNGLKEIIEKYRPEAIAVEELFFNKNIKTALAVGHGRGVAVLAAAQSGIDVFEY TPIQVKQSIVGYGRAEKTQVQQMVKAILNLPAIPKPDDVADALAVAVCHAHSYKMISY GL" misc_feature 29277..29732 /locus_tag="ClothDRAFT_1698" /note="Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD includes...; Region: RuvC_resolvase; cd00529" /db_xref="CDD:29627" misc_feature order(29292..29294,29472..29474,29691..29693,29700..29702) /locus_tag="ClothDRAFT_1698" /note="active site" /db_xref="CDD:29627" misc_feature order(29304..29306,29373..29375,29490..29492,29511..29513, 29586..29588,29595..29597,29628..29630) /locus_tag="ClothDRAFT_1698" /note="putative DNA-binding cleft; other site" /db_xref="CDD:29627" misc_feature order(29409..29411,29418..29420,29481..29483,29496..29498, 29505..29510,29517..29522,29526..29531,29538..29540, 29550..29555) /locus_tag="ClothDRAFT_1698" /note="dimer interface; other site" /db_xref="CDD:29627" gene 29808..30416 /locus_tag="ClothDRAFT_1699" CDS 29808..30416 /locus_tag="ClothDRAFT_1699" /inference="protein motif:TFAM:TIGR00084" /note="KEGG: slo:Shew_2076 Holliday junction DNA helicase RuvA; TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; RuvA domain protein; SMART: Helix-hairpin-helix DNA-binding class 1" /codon_start=1 /transl_table=11 /product="Holliday junction DNA helicase RuvA" /protein_id="ZP_05429838.1" /db_xref="GI:256004864" /db_xref="InterPro:IPR000085" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR011114" /db_xref="InterPro:IPR013849" /translation="MFAYIRGRLEYKNNDFLIVESNGVGYRIFTSLSTISGIGEIGQE VKVYTYLYVREDVISLYGFLTQEELNVFELLISVSGVGPKAAVSVLSAISPSRFSLAV ITDDVKTLTKAQGIGKKIAQRIILELKDKIKKEQLTEYAQSEEGGKVLDTDSSKMAEA VSALMVLGYSPAEANKAVSAVYREDMDIETIIKNALKGLARP" misc_feature 29808..30407 /locus_tag="ClothDRAFT_1699" /note="Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116" /db_xref="CDD:178876" misc_feature 29808..29993 /locus_tag="ClothDRAFT_1699" /note="RuvA N terminal domain; Region: RuvA_N; pfam01330" /db_xref="CDD:110340" misc_feature 30270..30407 /locus_tag="ClothDRAFT_1699" /note="RuvA, C-terminal domain; Region: RuvA_C; pfam07499" /db_xref="CDD:148866" gene 30515..31507 /locus_tag="ClothDRAFT_1700" CDS 30515..31507 /locus_tag="ClothDRAFT_1700" /inference="protein motif:TFAM:TIGR00635" /note="KEGG: gme:Gmet_0746 Holliday junction DNA helicase B; TIGRFAM: Holliday junction DNA helicase RuvB; PFAM: AAA ATPase central domain protein; Holliday junction DNA helicase RuvB domain; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase" /codon_start=1 /transl_table=11 /product="Holliday junction DNA helicase RuvB" /protein_id="ZP_05429839.1" /db_xref="GI:256004865" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR004605" /db_xref="InterPro:IPR008823" /db_xref="InterPro:IPR008824" /db_xref="InterPro:IPR011704" /translation="MEDRLVGCRLSEEDVDEVSLRPRKFGEYIGQTKVKENLMVFIEA AKKRNEALDHVLLYGPPGLGKTTLAGIIASELGVNLRITSGPAIEKPGDLAAILTNLG NFDVLFIDEIHRLNRSVEEILYPAMEDYALDIIIGKGPSARSIRLDLPKFTLIGATTR AGLLTSPLRDRFGVINKLELYSVEELGQIVKRSARILNVGIEDEAAEEIARRARGTPR VANRILKRIRDFAQVKSDGFITKEIARTGLEALEVDEIGLDAVDRNLLMSIIEKFGGG PVGLDTLAATIGEEPDTIEDVYEPYLLQLGFINKTPRGRMATKLAYEHFGLKYE" misc_feature 30548..31501 /locus_tag="ClothDRAFT_1700" /note="Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080" /db_xref="CDD:178847" misc_feature 30599..31039 /locus_tag="ClothDRAFT_1700" /note="The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes...; Region: AAA; cd00009" /db_xref="CDD:99707" misc_feature 30689..30712 /locus_tag="ClothDRAFT_1700" /note="Walker A motif; other site" /db_xref="CDD:99707" misc_feature order(30692..30715,30842..30844,30989..30991) /locus_tag="ClothDRAFT_1700" /note="ATP binding site; other site" /db_xref="CDD:99707" misc_feature 30830..30847 /locus_tag="ClothDRAFT_1700" /note="Walker B motif; other site" /db_xref="CDD:99707" misc_feature 31025..31027 /locus_tag="ClothDRAFT_1700" /note="arginine finger; other site" /db_xref="CDD:99707" misc_feature 31274..31498 /locus_tag="ClothDRAFT_1700" /note="Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491" /db_xref="CDD:147589" gene 31576..32121 /locus_tag="ClothDRAFT_1701" CDS 31576..32121 /locus_tag="ClothDRAFT_1701" /inference="protein motif:PFAM:PF02677" /note="PFAM: protein of unknown function DUF208; KEGG: glo:Glov_1752 protein of unknown function DUF208" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF208" /protein_id="ZP_05429840.1" /db_xref="GI:256004866" /db_xref="InterPro:IPR003828" /translation="MKLLLHICCGPCAVYPVNVLREEGIYFEGLFYNPNIHPYDEFIR RKENVKKLSEIKNVPVKYMDDFSQEIWEKLGEDNEKRCNMCYALRIDKVAGYAKENGF DAFTTTLLVSPYQKHELIVELSKRAGEKYGIEFFYKDFRPGFRQGQQEAKELGLYRQK YCGCIISYREAEKLKSERKSK" misc_feature 31582..32085 /locus_tag="ClothDRAFT_1701" /note="Uncharacterized BCR, COG1636; Region: DUF208; cl00708" /db_xref="CDD:153948" gene 32262..33365 /locus_tag="ClothDRAFT_1702" CDS 32262..33365 /locus_tag="ClothDRAFT_1702" /inference="protein motif:TFAM:TIGR01175" /note="TIGRFAM: type IV pilus assembly protein PilM; KEGG: mxa:MXAN_5776 type IV pilus biogenesis protein PilM" /codon_start=1 /transl_table=11 /product="type IV pilus assembly protein PilM" /protein_id="ZP_05429841.1" /db_xref="GI:256004867" /db_xref="InterPro:IPR005883" /translation="MLLPFLRNNYLSIDIGFRNIKVVEVAVNRNNEVYINNFGIAPTP LNCIKNGVIKNVDAVSSEISRIIRENKMKVKKSKIVMSGTSIISRVFMIEKVPGKSID ELVQEAIMSNLPINPDEHKIDYKILQELKEDNVEKVKVFVTAVRKSIINSYIDVLFEL GLKPVSVDIPANSTAKFFNRDIKVSIDNVKFVNPNRSQLNKDAFAVIDFGSETTIINI LRNKILEFNKVILSGSSNLDEAIAKNMRKSIIEAERLKKLYGISVPPHHSTNEEHMKV YRILKEVVDKLLNQIYMCLTFYEARCYGVKVGKIFIIGGGSLLKGLADYMEQVLQVPV YPVGLLDIDGIDINKNLNSDKLNFLVNAVGITL" misc_feature 32280..33362 /locus_tag="ClothDRAFT_1702" /note="type IV pilus assembly protein PilM; Region: pilM; TIGR01175" /db_xref="CDD:162237" misc_feature 32385..32801 /locus_tag="ClothDRAFT_1702" /note="Cell division protein FtsA; Region: FtsA; cl11496" /db_xref="CDD:159497" misc_feature 32871..33257 /locus_tag="ClothDRAFT_1702" /note="Cell division protein FtsA; Region: FtsA; cl11496" /db_xref="CDD:159497" gene 33675..36521 /locus_tag="ClothDRAFT_1703" CDS 33675..36521 /locus_tag="ClothDRAFT_1703" /inference="protein motif:PFAM:PF01520" /note="PFAM: cell wall hydrolase/autolysin; copper amine oxidase domain protein; SMART: cell wall hydrolase/autolysin; KEGG: ecm:EcSMS35_3140 N-acetylmuramoyl-L-alanine amidase AmiC" /codon_start=1 /transl_table=11 /product="cell wall hydrolase/autolysin" /protein_id="ZP_05429842.1" /db_xref="GI:256004868" /db_xref="InterPro:IPR002508" /db_xref="InterPro:IPR012854" /translation="MKRGLFVLFVAMVLVFNSFTMCAEALKLTYDGKVHEYTGNIYTL KVDGEVVNSDLPPIIINGRSLVPVRAIFEKLGAKVGWDAASKKVTISYDSNTIELKIN DVNALVNGTKVAMEVPAKIINDRTVVPVRFVGEQLGMEVGWNAEKGEITLDSGKSVVA SINDINYKIDGNLHQVKIELDKCREYKIMRVANPDRIVVDFPNTKLSNANTNISVGSE LISSIRCGNPDTKTARVVLDVVGQPQYIVKEEGSNVVLNLQKPNTGRPSGTVGSNKLD VEHVSKTDHDEVYIKCGTAPEYNSFTLSDPERIVIDVSGAYIEGEIKNIETKGNLVKS VRCANQSGNVARVVVDLQQKLNHKIIKSGEYLIVYISRAPISENPAVSLPSRGGTGKD EGSRDNILYVAYEPDGQKDKVVLSLDSYENYNIVKNVEKNKIIIDIPNAIGPSEAKTI SVDSDMVSSVKYVGFDKSYAQVEIGLKSKIQYEVIEKEGRLELVLSKAAEVSPSPSPT PTPTPTPTQTPTSTPTPTQSPTPTPTPTPVQVVKDGSLSIAYNVASTYSKVILGIQNY KNYNVNRISDPDRIVIDITGANVEKTANTVEIKKGFIEAIRYSQYEVGVVRVVIDVKD NPKHDVKKSGDKLEIYLKDSVSGQNYKNIKYVNNMDRIHFILQGAKLTEGGADLKKFY TEKYDLGGKRYTITFPSNLADIGSGIMQINDGIVDYVKITQNPDTKQTSMEFNTKEAY SYLIITRGDVNNTTITLLKKASRDDKLVVIDPGHGGLETGAVYGDCYEKDFNLDIAKR LNALLKSKGVKTYMIREDDSYVGLYERAYIANTLNATLFLSIHNNAYNTKSHGTETLY YPTPAGATGFTSKRFAQIIQSRLVSKLKTKDRGIVERPNLVVLKATKMPAALAEVAFM DNSEELQKLKTEEFRQKAAEALCEAVIQALAEVE" sig_peptide 33675..33752 /locus_tag="ClothDRAFT_1703" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.973) with cleavage site probability 0.884 at residue 26" misc_feature <33753..33944 /locus_tag="ClothDRAFT_1703" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature 33852..34130 /locus_tag="ClothDRAFT_1703" /note="Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833" /db_xref="CDD:149091" misc_feature 34149..34448 /locus_tag="ClothDRAFT_1703" /note="Localisation of periplasmic protein complexes; Region: AMIN; pfam11741" /db_xref="CDD:152177" misc_feature 34500..34781 /locus_tag="ClothDRAFT_1703" /note="Localisation of periplasmic protein complexes; Region: AMIN; pfam11741" /db_xref="CDD:152177" misc_feature <35379..35594 /locus_tag="ClothDRAFT_1703" /note="Localisation of periplasmic protein complexes; Region: AMIN; pfam11741" /db_xref="CDD:152177" misc_feature 35976..36497 /locus_tag="ClothDRAFT_1703" /note="N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696" /db_xref="CDD:119407" misc_feature order(35994..35996,36036..36038,36195..36197,36402..36404) /locus_tag="ClothDRAFT_1703" /note="active site" /db_xref="CDD:119407" misc_feature order(35994..35996,36036..36038,36195..36197) /locus_tag="ClothDRAFT_1703" /note="metal-binding site" /db_xref="CDD:119407" gene 36661..37725 /locus_tag="ClothDRAFT_1704" CDS 36661..37725 /locus_tag="ClothDRAFT_1704" /inference="protein motif:TFAM:TIGR01179" /note="TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: dds:Ddes_1950 UDP-glucose 4-epimerase" /codon_start=1 /transl_table=11 /product="UDP-glucose 4-epimerase" /protein_id="ZP_05429843.1" /db_xref="GI:256004869" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR002198" /db_xref="InterPro:IPR002225" /db_xref="InterPro:IPR003869" /db_xref="InterPro:IPR005886" /db_xref="InterPro:IPR005913" /db_xref="InterPro:IPR013120" /translation="MQKQGAYGFVILGGIINNRGKVVFEVAVLVTGGAGYIGSHTVAE LVEKKEEVIVVDNLEKGHRDAVAGAKLIVGDLRDKEFVKKVFLENDIEAVIHFAAYIE VGESVQNPLKYYNNNVIATLNLLTAMEEAKVDKIVFSSTAATYGEPENIPILETDRTL PTNPYGETKLAVEKALKWCDRAYGIKYIALRYFNASGAHESGEIGEDHSPESHLIPLV IQAALGKRESIKIFGNDYNTPDGTCIRDYIHVSDLANAHYLALQRLREGKESAVYNLG NGKGFSVKEVIDVVRKVTGRPIKVEDAPRRPGDPAVLVASSEKIKKELNWQPRMADLE TIVSTAWKWHLSHPNGYNDK" misc_feature 36739..37713 /locus_tag="ClothDRAFT_1704" /note="UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087" /db_xref="CDD:31284" misc_feature 36742..>37125 /locus_tag="ClothDRAFT_1704" /note="Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931" /db_xref="CDD:186874" gene 37828..39000 /locus_tag="ClothDRAFT_1705" CDS 37828..39000 /locus_tag="ClothDRAFT_1705" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429844.1" /db_xref="GI:256004870" /translation="MKKLGCLVIALLVAFLFGCQVPTDKTTENENGVNSPDIDKEVMS LNDAIDEKENGERNEEGAAGESGKESSKSPEAWKESVLSTVEPSVENGESKEKSKEKT KIAVTVYYRDSDNCLIPITRDIYKEEGIAKAALRCMVDNDSNRSAVQSLGLYPVLPEG TEILGMNIKDGIATVDFNSRILDYKDKTAENNIVAGVVYCLTEFSTIDGVKILVEGME KEKLQYGADISGVLDRDNVLINSDKVNLQDKLKKADIYMFKYIKDKNEFIIPISMEYI GVPEEELPAQIIRMLAEKPANERIYSLIPSGVEVLGSRIEGNLLILDFNKEIKNYGGT AREEGILKQILYSMKQLKNIEKIRILIEGKKDHLPEGTDISGEMLLPVEINRQKDL" sig_peptide 37828..37884 /locus_tag="ClothDRAFT_1705" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.987) with cleavage site probability 0.931 at residue 19" misc_feature 38143..38493 /locus_tag="ClothDRAFT_1705" /note="Sporulation and spore germination; Region: Germane; pfam10646" /db_xref="CDD:151159" misc_feature 38605..38937 /locus_tag="ClothDRAFT_1705" /note="Sporulation and spore germination; Region: Germane; pfam10646" /db_xref="CDD:151159" gene 39068..39859 /locus_tag="ClothDRAFT_1706" CDS 39068..39859 /locus_tag="ClothDRAFT_1706" /EC_number="2.7.7.56" /inference="protein motif:TFAM:TIGR01966" /note="KEGG: geo:Geob_3021 ribonuclease PH; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2" /codon_start=1 /transl_table=11 /product="ribonuclease PH" /protein_id="ZP_05429845.1" /db_xref="GI:256004871" /db_xref="InterPro:IPR001247" /db_xref="InterPro:IPR002381" /db_xref="InterPro:IPR015847" /translation="MLRIDGRGQSDLRPVKITRNYIKHAEGSVLIEMGDTKVICTATV DDKVPPFKKNTGEGWVTAEYSMLPRATAARNPRDISKLKLSGRSQEIQRLIGRALRSV VNLNLLGEREIIIDCDVIQADGGTRTASITGGFVALVDACKKLVDDGIIEKIPVTDFL AAVSVGIVDGVEMLDLCYMEDSNAATDMNVVMTSKGEFIEIQATGEQLPFKKEQFDKL LSFAEKGISQLIEIQKDALGQVASEVGRVTKDEKICNCNEEQGQA" misc_feature 39074..39784 /locus_tag="ClothDRAFT_1706" /note="ribonuclease PH; Reviewed; Region: rph; PRK00173" /db_xref="CDD:178914" misc_feature 39098..39490 /locus_tag="ClothDRAFT_1706" /note="3' exoribonuclease family, domain 1; Region: RNase_PH; pfam01138" /db_xref="CDD:144653" misc_feature 39539..39742 /locus_tag="ClothDRAFT_1706" /note="3' exoribonuclease family, domain 2; Region: RNase_PH_C; pfam03725" /db_xref="CDD:146389" gene 39816..40415 /locus_tag="ClothDRAFT_1707" CDS 39816..40415 /locus_tag="ClothDRAFT_1707" /inference="protein motif:TFAM:TIGR00042" /note="TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein; KEGG: vcj:VCD_001151 nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific)" /codon_start=1 /transl_table=11 /product="non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family" /protein_id="ZP_05429846.1" /db_xref="GI:256004872" /db_xref="InterPro:IPR002637" /translation="MRKFVIATKNKGKLKEIQEILDGLDFEVVSMEEMGITKDIEESG STFEENALIKAREVYKACGEIVMADDSGLEVDYLNGAPGIYSSRFAGEGASDEDRNNK LLSLLKDVPFEQRKARFVCVIAVILSDEEYFTVRGTVEGYIGFEPKGDNGFGYDPLFF IPEYNMTAAQMKPSKKHEISHRGKAMRMMLEELKKRLDL" misc_feature 39828..40388 /locus_tag="ClothDRAFT_1707" /note="NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A Ham1-...; Region: HAM1; cd00515" /db_xref="CDD:29953" misc_feature order(39843..39845,39849..39854,39861..39863,40026..40034, 40071..40076,40170..40172,40272..40274,40278..40283, 40356..40361) /locus_tag="ClothDRAFT_1707" /note="active site" /db_xref="CDD:29953" misc_feature order(39939..39947,40047..40052,40059..40061,40068..40070, 40077..40079) /locus_tag="ClothDRAFT_1707" /note="dimerization interface; other site" /db_xref="CDD:29953" gene 40832..42634 /locus_tag="ClothDRAFT_1708" CDS 40832..42634 /locus_tag="ClothDRAFT_1708" /inference="protein motif:PFAM:PF00079" /note="PFAM: proteinase inhibitor I4 serpin; cellulosome protein dockerin type I; SMART: proteinase inhibitor I4 serpin; KEGG: similar to Serpin B6 (Placental thrombin inhibitor) (Cytoplasmic antiproteinase) (CAP) (Proteinase inhibitor 6) (PI-6)" /codon_start=1 /transl_table=11 /product="proteinase inhibitor I4 serpin" /protein_id="ZP_05429847.1" /db_xref="GI:256004873" /db_xref="InterPro:IPR000215" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MQKKLICFLVFALLSSFLFVGNSFADGNWKTYYELYPDPVVTDT SAVIRFKIIKVKIDDYITMPGYVYDVEYWKTDEPSNVMHSYNILWGESSKQISEGISE VVYRTELTGLEPNTEYTYKIYGQMPIRNKEGTPETITFKTLPKKLVYGELNGDGKINS SDLNMMKRYLLRLIDGLNDTACADLNGDGKINSSDYSILKRYLLRMIDKFPVEKEEKN EGVSENFIRGNSNFAFNIFKEINKDEQGKNVFISPFGISTALSMVYQGAKSDTREEMA KVLGYEGLDIEEVNKSYKYLLQYFNGLDNDTKIKSSNSIWMNSLHGNAIKEDFISTNK DVFDALAETRDFSDKGVVDEINDWISKATEGQIDKMLSEIDMDMLAYIISALYFKGTW TEEFDIEKTVSVPFASEDGGADHVMMMRKELCTIEFGEGDGYKAVRLPYGDGEMAMYC ILPDEDTSINDFIQKLDLSMWEKIKNSITKRENGTIYLPRFKMEYAKGESGSIMESLK ALGMKKAFEEDADLSGMTEADAFISDVLHKAVVEVNEKGTEASGVVVIPIAPTSIAPG PKFIANRPFAFVIADEKYDTILFMGKLCDGGLIN" sig_peptide 40832..40909 /locus_tag="ClothDRAFT_1708" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 26" misc_feature 40952..41206 /locus_tag="ClothDRAFT_1708" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065" /db_xref="CDD:153489" misc_feature 41285..41344 /locus_tag="ClothDRAFT_1708" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 41381..41443 /locus_tag="ClothDRAFT_1708" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 41492..42610 /locus_tag="ClothDRAFT_1708" /note="serpin-like protein; Provisional; Region: PHA02660" /db_xref="CDD:165039" misc_feature 41504..42610 /locus_tag="ClothDRAFT_1708" /note="SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which...; Region: SERPIN; cl00137" /db_xref="CDD:176415" misc_feature order(42470..42481,42536..42553) /locus_tag="ClothDRAFT_1708" /note="reactive center loop; other site" /db_xref="CDD:29117" gene 43065..44864 /locus_tag="ClothDRAFT_1709" CDS 43065..44864 /locus_tag="ClothDRAFT_1709" /inference="protein motif:PFAM:PF00079" /note="PFAM: proteinase inhibitor I4 serpin; cellulosome protein dockerin type I; SMART: proteinase inhibitor I4 serpin; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="proteinase inhibitor I4 serpin" /protein_id="ZP_05429848.1" /db_xref="GI:256004874" /db_xref="InterPro:IPR000215" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /translation="MLPGFALLSSFLLVGNSFAANWYTYYELYPDPVVTDTSAVIRFK LTTEKIDDYITMPGYIYEFRYWKVDEPSKVKSVSIGLYVNEVQTVELTDLEPNTEYEC KVWGQIYTSNKEGTPKTITFKTLPKKGDLNGDAKINSTDLNMMKRYLLQMIDRFGVDD ESCADLNGDGKITSSDYNLLKRYILHLIDKFPIGNDETDEGINDGFNDETDEDINDSF IEANSKFAFDIFKQISKDEQGKNVFISPFGISMALSMVYQGAESDTREEMAKVLGYEG LDIEEVNKSYKLLLKYFNELIGNVKLKNSNSIWKNSLKGDVIKEDFISVNKDVFNALV ETRDFSDESVVDKINNWISDATEGKVKKALNAVNPDELLYIISALYFNGAWKEEFEFD INDTTMSTFKSEDGSTDYVMMMRKSYNNWVGVMEFGKGDGYSAIRLPYGNGEMAMYCI LPDEDISINDFIQNLDVSLWNEIKNSIRKTLQGLICLPRFKIEYFKDGNGSIKESLKA LGLEKVFSLAEADLTGMSETNAYVSDVLHKAVVEVNEKGTEASSSVVVIPVPGFGTRS EFIADRPFVFIIADEKYDTILFMGKLAKGELIN" sig_peptide 43065..43124 /locus_tag="ClothDRAFT_1709" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 20" misc_feature 43164..43376 /locus_tag="ClothDRAFT_1709" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065" /db_xref="CDD:153489" misc_feature 43557..43619 /locus_tag="ClothDRAFT_1709" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 43704..44843 /locus_tag="ClothDRAFT_1709" /note="serpin-like protein; Provisional; Region: PHA02660" /db_xref="CDD:165039" misc_feature 43716..44840 /locus_tag="ClothDRAFT_1709" /note="SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which...; Region: SERPIN; cl00137" /db_xref="CDD:176415" misc_feature order(44703..44714,44766..44783) /locus_tag="ClothDRAFT_1709" /note="reactive center loop; other site" /db_xref="CDD:29117" gene 45063..45136 /locus_tag="ClothDRAFT_R0034" /note="tRNA-Gly4" tRNA 45063..45136 /locus_tag="ClothDRAFT_R0034" /product="tRNA-Gly" gene 45151..45227 /locus_tag="ClothDRAFT_R0035" /note="tRNA-Arg1" tRNA 45151..45227 /locus_tag="ClothDRAFT_R0035" /product="tRNA-Arg" gene 45415..46599 /locus_tag="ClothDRAFT_1710" CDS 45415..46599 /locus_tag="ClothDRAFT_1710" /inference="protein motif:PFAM:PF00999" /note="PFAM: sodium/hydrogen exchanger; KEGG: sfu:Sfum_1529 sodium/hydrogen exchanger" /codon_start=1 /transl_table=11 /product="sodium/hydrogen exchanger" /protein_id="ZP_05429849.1" /db_xref="GI:256004875" /db_xref="InterPro:IPR006153" /translation="MAASLAIILLLGLPAKRIFEKLRLPGLLGMLILGILIGPHVLNL LQTDMLQISSDLRSIALIIILLRAGLGLNKDELKSIGIPALKMSCIPGLFEGLFIALA SVYFLDFTFVQGGMLGFIIAAVSPAVVVPFMLKLNENKIGTKKGVPTLILAGASIDDV FAITVFSAFLGLYYGSEINIGIQLLNIPISILLGILSGILVGFLLINIFKKYNIPDTK KVLLILGFSILLNQLESVLKTKLRIASLLGVMAIGFILTEYLPDTGKKLSDKFNKVWV FAEILLFVLVGAEVNVNVALKAGGIGIILILTGLIGRSVGVAISLLGTDFNWKERVFC IIAYIPKATVQAAMGAVPLSLGVESGDIILAIAVLAILITAPLGAIGIHYSAEKLLIE KQ" misc_feature 45631..46497 /locus_tag="ClothDRAFT_1710" /note="Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999" /db_xref="CDD:144551" gene 46687..47070 /locus_tag="ClothDRAFT_1711" CDS 46687..47070 /locus_tag="ClothDRAFT_1711" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429850.1" /db_xref="GI:256004876" /translation="MSKKGISCALISLILVIFLSATVFAEETITAKLKSYTAYEYPYL MLEHVMGPERTVYYAICYNSEGQVEYGEIIREIDDFVLSRVYLDGTSEDFEPPQLTIQ QIREFAEKYPKYEYDICDWPLSYIL" sig_peptide 46687..46764 /locus_tag="ClothDRAFT_1711" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 26" gene 47290..47436 /locus_tag="ClothDRAFT_1712" CDS 47290..47436 /locus_tag="ClothDRAFT_1712" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429851.1" /db_xref="GI:256004877" /translation="MVNNDGILIERILKGDNTGFNRNKDFLPWVFKIAFNLYRNFYKK IKRS" misc_feature <47347..>47433 /locus_tag="ClothDRAFT_1712" /note="RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; Region: Sig-70_gvs1; TIGR02989" /db_xref="CDD:132034" gene 47493..47786 /locus_tag="ClothDRAFT_1713" CDS 47493..47786 /locus_tag="ClothDRAFT_1713" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="RNA polymerase, sigma-24 subunit, ECF subfamily" /protein_id="ZP_05429852.1" /db_xref="GI:256004878" /translation="MLLLEKAGSLKEILLFVDELKKDQKEIFILKYGKGFTFKTIAEI TGISEIEKSNAELKKSGWIEIPEIKSKEIVYVNKKGRTITHMRNKIRRYYYAS" misc_feature 47520..>47639 /locus_tag="ClothDRAFT_1713" /note="Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...; Region: Sigma70_r4; cl01055" /db_xref="CDD:186312" gene complement(47944..50037) /locus_tag="ClothDRAFT_1714" CDS complement(47944..50037) /locus_tag="ClothDRAFT_1714" /inference="protein motif:PFAM:PF00120" /note="PFAM: glutamine synthetase catalytic region; KEGG: ppd:Ppro_1682 glutamine synthetase, catalytic region" /codon_start=1 /transl_table=11 /product="glutamine synthetase catalytic region" /protein_id="ZP_05429853.1" /db_xref="GI:256004879" /db_xref="InterPro:IPR008146" /translation="MQDIPNVFGSMVFNDKVMKQRLPKDVYKALKRTMDEQKHLNLDV ANVVATAMKEWAIEKGATHFTHWFQPLTGVTAEKHDSFISPVGDGNVIMEFSGKELVR GEPDASSFPSGGIRSTFEARGYTAWDPTSYAFIKDNTLCIPTAFCSYSGEALDKKTPL LRSMEAIDKQAKRILKIFGNDNVKRVAATVGPEQEFFLIDKELYQKRPDLIYCGRTLF GARPPKGQELEDHYFASIKPRVSAFMKELDEELWKLGVLAKTKHNEVAPAQHEVAPIF TTVNIAADHNQLIMELMKTIANKHDLVCLLHEKPFAGVNGSGKHNNWSISTDTGINLL EPGETPYDNAQFLVFLCAVIKAVDEYQDLLRISIASAGNDHRLGANEAPPAIISVFLG EELTAILEAIENGTGYNKKEKVQMEIGASVLPHFPKDNTDRNRTSPFAFTGNKFEFRM LGSSASISDANTVLNTIVAEALCQFADRLENAGDFRAELNALIKETIKKHRRIIFNGN NYSEEWVKESEKRGLLNLKSVVEAAPYLISEKNIKLFTKHNIFSESEIHSRYNIMLEE YIKVLHIEALTILDMTKRGIIPAVVEYLKDLTEVVKNKKAISSEFNCKLEESLINTIS DLAACLYKNVEKLDNSILEAKNQDGLLNTAKYYREVVFINMQELRSVIDNLETKIGKK YWPFPTYGELLYSVY" misc_feature complement(47950..50037) /locus_tag="ClothDRAFT_1714" /note="Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968" /db_xref="CDD:33749" misc_feature complement(49549..50034) /locus_tag="ClothDRAFT_1714" /note="Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437" /db_xref="CDD:152871" misc_feature complement(48889..49482) /locus_tag="ClothDRAFT_1714" /note="Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120" /db_xref="CDD:143894" gene 50629..51720 /locus_tag="ClothDRAFT_1715" CDS 50629..51720 /locus_tag="ClothDRAFT_1715" /inference="protein motif:PFAM:PF00310" /note="PFAM: glutamine amidotransferase class-II; KEGG: gur:Gura_2491 glutamine amidotransferase, class-II" /codon_start=1 /transl_table=11 /product="glutamine amidotransferase class-II" /protein_id="ZP_05429854.1" /db_xref="GI:256004880" /db_xref="InterPro:IPR000583" /translation="MLKEGQIRIPSGCAISGIFSKSGKRISGEAIIKSIATMRDRSNG LGGGFAGYGIYPEYKDFYAFHIFYDGDVAKEECEKFLERHFDIINLSKIPTKKTKGIT DAPLIWRYFVTPLPTKLDESQLDEREYTARCVMKINKKIDGAYVFSSGKNMGVFKAVG FPEDVGEFYKLYDYAGYCWTAHGRYPTNTPGWWGGAHPFALLDYSVVHNGEISSYDAN RRTIEMYGYKCTLLTDTEVITYIIDYLNRKVGLTLEEIAGVVAAPFWQVIDNMPEEQK EKYTYLRNVFSSMLITGPFSILAGFEGGIMALNDRLKLRSMVVGEKDDMFYAASEECA IRVLEENLDRVWAPKGGEPVIATLNRGVL" misc_feature 51049..51696 /locus_tag="ClothDRAFT_1715" /note="Glutamine amidotransferases class-II (Gn-AT)_GlxB-type. GlxB is a glutamine amidotransferase-like protein of unknown function found in bacteria and archaea. GlxB has a structural fold similar to that of other class II glutamine amidotransferases...; Region: GlxB; cd01907" /db_xref="CDD:73286" misc_feature order(51178..51183,51253..51258,51328..51330) /locus_tag="ClothDRAFT_1715" /note="putative active site; other site" /db_xref="CDD:73286" gene 51720..53225 /locus_tag="ClothDRAFT_1716" CDS 51720..53225 /locus_tag="ClothDRAFT_1716" /EC_number="1.4.1.13" /inference="protein motif:PRIAM:1.4.1.13" /note="PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvm:DvMF_0546 glutamate synthase (NADPH)" /codon_start=1 /transl_table=11 /product="Glutamate synthase (NADPH)" /protein_id="ZP_05429855.1" /db_xref="GI:256004881" /db_xref="InterPro:IPR001450" /db_xref="InterPro:IPR002932" /db_xref="InterPro:IPR017900" /translation="MGINFLYPEYEVVRNMDRCINCRVCERQCANEVHSYDQEKKIMC SDDSKCVNCHRCVALCPTRALKIVKTDHTFKENANWRGSIINEIYKQAESGAVLLSSM GNPNEYPVYFDKILLNASQVTNPSIDPLREPMETKVFLGSKPRSIQRDEKGKLVNNLS CGIELSVPIMFSAMSYGSISYNAHESLARAAKEAGILYNTGEGGLHRDLYQYGSNTIV QVASGRFGVHKDYLEAGAAIEIKMGQGAKPGIGGHLPGTKIVGDISRTRMVPEGSDAI SPAPHHDIYSIEDLRQLVYSLKEATNYTKPVIVKIAAVHNVAAIASGIARSGADIIAI DGFRGGTGAAPTRIRDNVGIPIELALASVDQRLREEGIRDNVSIVVGGSIRNSSDVVK AVALGADCVYIGTAALIALGCHLCRSCHTGKCNWGIATQEPELVKRLNPDMGYKRLVN LVNAWKHEIKEMMGGMGINSIESLRGNRLMLRGVGLNEKELQILGIKHAGE" misc_feature <51723..>51989 /locus_tag="ClothDRAFT_1716" /note="The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved alpha-; Region: HCP_like; cl14655" /db_xref="CDD:187409" misc_feature 52023..53159 /locus_tag="ClothDRAFT_1716" /note="Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant...; Region: GltS_FMN; cd02808" /db_xref="CDD:73370" misc_feature 52038..53126 /locus_tag="ClothDRAFT_1716" /note="Conserved region in glutamate synthase; Region: Glu_synthase; pfam01645" /db_xref="CDD:110632" misc_feature order(52233..52244,52323..52325,52374..52376,52440..52442, 52458..52460,52518..52520,52647..52649,52737..52745, 52860..52862,52866..52868,52929..52934,52956..52958, 52974..52976,52989..52991) /locus_tag="ClothDRAFT_1716" /note="active site" /db_xref="CDD:73370" misc_feature order(52233..52244,52323..52325,52374..52376,52440..52442, 52647..52649,52737..52742,52860..52862,52866..52868, 52929..52934) /locus_tag="ClothDRAFT_1716" /note="FMN binding site; other site" /db_xref="CDD:73370" misc_feature order(52458..52460,52518..52520,52740..52745) /locus_tag="ClothDRAFT_1716" /note="substrate binding site; other site" /db_xref="CDD:73370" misc_feature order(52956..52958,52974..52976,52989..52991) /locus_tag="ClothDRAFT_1716" /note="3Fe-4S cluster binding site; other site" /db_xref="CDD:73370" gene 53239..53667 /locus_tag="ClothDRAFT_1717" CDS 53239..53667 /locus_tag="ClothDRAFT_1717" /inference="protein motif:PFAM:PF00037" /note="PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gme:Gmet_1755 iron-sulfur cluster-binding protein" /codon_start=1 /transl_table=11 /product="4Fe-4S ferredoxin iron-sulfur binding domain protein" /protein_id="ZP_05429856.1" /db_xref="GI:256004882" /db_xref="InterPro:IPR001450" /translation="MKRVYVNEKWCLACHLCEYYCAFANSNEKDMVKALKDIVINPRI RVEQKDNISFAVSCRHCEEPLCVKGCITGALSVKDGVISVDQNKCVGCFTCILCCPYG AVSPGEKSVIQKCELCTNNIHGTPQCVKGCPNNAIVFEER" misc_feature 53239..>53649 /locus_tag="ClothDRAFT_1717" /note="putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769" /db_xref="CDD:183733" gene 53672..54907 /locus_tag="ClothDRAFT_1718" CDS 53672..54907 /locus_tag="ClothDRAFT_1718" /inference="protein motif:PFAM:PF00070" /note="PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gme:Gmet_1754 FAD-dependent pyridine nucleotide-disulphide oxidoreductase" /codon_start=1 /transl_table=11 /product="FAD-dependent pyridine nucleotide-disulphide oxidoreductase" /protein_id="ZP_05429857.1" /db_xref="GI:256004883" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR001327" /db_xref="InterPro:IPR013027" /translation="MKYVIIGNSIAAVGAVEGIRKIDTEGEITIIGKEPYHVYSRPLI SYLLYGKTDEERMKYRGSSFYDTMNCKVILGREAVKINDAKKEVVLDNGEVINYDKLL VATGSLPFVPPMKGLEGVEKRFSFLSLDDAKKLESAISPSSKVLIIGAGLIGLKCAEG ISKKVESITVVDLADRILSSILDKDGAEIVKSHIEKENIKFVLNAKVEEFINSNEALL DSGEKVEFDVLVVAVGVIPNTGLIKDINGKVNRGIVVDEFCQTSIPDIYAAGDCCESF DITSEQNRVLALLPNAYMQGECAGINMAGGKKEFGKAIPMNAISFFGLHIITAGSYVG EVFSKINGDNYKKLFVKDGLLKGYIMIGDVDKAGIYTSLIREKTPLSEIDFELIFERP GLMAFTRKERQRMLGGVVR" misc_feature 53672..>54838 /locus_tag="ClothDRAFT_1718" /note="NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251" /db_xref="CDD:31443" misc_feature 54101..54325 /locus_tag="ClothDRAFT_1718" /note="Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; cl14644" /db_xref="CDD:187400" gene 54904..55626 /locus_tag="ClothDRAFT_1719" CDS 54904..55626 /locus_tag="ClothDRAFT_1719" /inference="protein motif:PFAM:PF01493" /note="PFAM: glutamate synthase alpha subunit domain protein; KEGG: gsu:GSU1235 hypothetical protein" /codon_start=1 /transl_table=11 /product="glutamate synthase alpha subunit domain protein" /protein_id="ZP_05429858.1" /db_xref="GI:256004884" /db_xref="InterPro:IPR002489" /translation="MIINAQNLYYKELNQKIREASDKDIVIENCLGQRYIGDGQGNKN ITIYGTPGNDLGAYLDGCTIRVMGNAQDATGDTMNDGTIYIHGNSGDVCGYAMRGGKI FIRDNAGYRTGIHMKQYKEKKPVIVIGGTAGSFLGEYLAGGIIIVLGLNSEDTVPVGD FCGTGMHGGKIYLRCSRLPQDLPKQVIAREANEEDMEEIKGYIEEFCREFGKDKEQIL NSKFFCLVPNTKNPYKQLYTHN" misc_feature 54904..55590 /locus_tag="ClothDRAFT_1719" /note="Archaeal-type gltB domain. This domain shares sequence similarity with a region of unknown function found in the large subunit of glutamate synthase, which is encoded by gltB and found in most bacteria and eukaryotes. It is predicted to be homologous...; Region: arch_gltB; cd00981" /db_xref="CDD:29610" misc_feature order(54991..54996,55051..55053,55060..55065,55075..55077, 55108..55116,55129..55131,55138..55140,55165..55170, 55177..55179,55186..55188,55195..55197,55222..55236, 55243..55248,55252..55254,55294..55305,55315..55320, 55324..55326,55384..55386,55393..55395,55402..55404) /locus_tag="ClothDRAFT_1719" /note="putative subunit interface; other site" /db_xref="CDD:29610" gene 55659..56981 /locus_tag="ClothDRAFT_1720" CDS 55659..56981 /locus_tag="ClothDRAFT_1720" /inference="protein motif:TFAM:TIGR00653" /note="TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: dat:HRM2_45740 GlnA2" /codon_start=1 /transl_table=11 /product="glutamine synthetase, type I" /protein_id="ZP_05429859.1" /db_xref="GI:256004885" /db_xref="InterPro:IPR004809" /db_xref="InterPro:IPR008146" /db_xref="InterPro:IPR008147" /translation="MSYNIKIKEVLEFVEENDVKFIRLAFCDILGIPKNISIMPQELE RAFEQGISFDASSILGFMNVEKSDLFLHPDPSTLSILPWRPQQGRVIRFFCDIKHPDG SAFEGDSRNILKKAVERAEKMGYACRIGSECEFYLFETDEKGRPTYIPHDEGGYLDMA PLDKGENVRREICLSLEQMGIQPESSHHEQGPGQHEIDFKYSDALTAADDLMTFKTVV KAVASRNGLFASFMPKPILTESGSGLHINISLSKDGFNIFKERNYDSSAAKSFIAGVI DKILDITAFANPITNSYARLGSFRAPKYVSWSHQNRSQLIRIPAETGEYSRMELRSPD PACNPYITFALILHAGLDGIERKLELPGPINQNLYNAGADELQNIKALPQNLKEALDV ASKSSFVRNILGEEMLSKYLEIKLKEWNMYFESEDRESVEKQMYFKII" misc_feature 55680..56924 /locus_tag="ClothDRAFT_1720" /note="glutamine synthetase, type I; Region: GlnA; TIGR00653" /db_xref="CDD:161979" misc_feature 55710..55958 /locus_tag="ClothDRAFT_1720" /note="Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951" /db_xref="CDD:146534" misc_feature 55974..56708 /locus_tag="ClothDRAFT_1720" /note="Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120" /db_xref="CDD:143894" gene 57009..57581 /locus_tag="ClothDRAFT_1721" CDS 57009..57581 /locus_tag="ClothDRAFT_1721" /inference="protein motif:PFAM:PF03861" /note="PFAM: ANTAR domain protein; KEGG: ppd:Ppro_3459 response regulator receiver/ANTAR domain-containing protein" /codon_start=1 /transl_table=11 /product="response regulator receiver and ANTAR domain protein" /protein_id="ZP_05429860.1" /db_xref="GI:256004886" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR005561" /translation="MDSILIVSSSLKVSSTLEELLKFNSSYNEIVMARNAGEAKRILL DRDFDLCIINTPLTDEFGTNLAINIANRETSQVMLIVKSELEDEISDKVEDYGIFVVA KPVNRQLFWSALKLISASHNRMKGLKKQNEQLQKKIEDIKFVDRAKCVLIEYLKMSEA EAHRFIEKQAMDLRVTKREIASRILKTYEK" misc_feature 57396..57563 /locus_tag="ClothDRAFT_1721" /note="ANTAR domain; Region: ANTAR; pfam03861" /db_xref="CDD:146474" gene 57861..58148 /locus_tag="ClothDRAFT_1722" CDS 57861..58148 /locus_tag="ClothDRAFT_1722" /inference="protein motif:PFAM:PF06961" /note="PFAM: protein of unknown function DUF1294; KEGG: tau:Tola_0691 protein of unknown function DUF1294" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1294" /protein_id="ZP_05429861.1" /db_xref="GI:256004887" /db_xref="InterPro:IPR010718" /translation="MPNNPYTYVFLLFAIINLVGFVITGIDKYKASRSLWRIHERTFF WLVLMGGAPGVYLGLLVFRHKTRRMSFMIGIPLIFAFQILGIILLYVLSET" misc_feature 57909..58073 /locus_tag="ClothDRAFT_1722" /note="Protein of unknown function (DUF1294); Region: DUF1294; cl01311" /db_xref="CDD:154327" gene 58439..60397 /locus_tag="ClothDRAFT_1723" CDS 58439..60397 /locus_tag="ClothDRAFT_1723" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429862.1" /db_xref="GI:256004888" /translation="MLLERYKYMVDTLKVPSEKILILLLNRTQSLEWRTKTFLEGSGA ILRTSYFGFIQEEIRTYYPLIVKNCSEIVNKNVKPVFLTFEASQFLVSIVLDWRRQKK GAFAGVTSFSDRLAIDMTSNLVKAAISDIPYDEIGKRLYNALEKKEEIRKRVYDEADE IIRDYRKKCMELGIFDFGMAVELYNKCLLPDETYQNQLFRRIEHLIVDNIEECVPSEV DFINFLLPKLKTCLLGYNHEGGYGQAFGSNHEYVKQQLIDKMEIVELNKSYTCKDFMY EFSDMLFDFIENSAPCKFKARPEIERVPPLELRSDMLEKAGDRIIELIEDEGYNPSDI VVISNYADPVTEFVIGRILERHGYEIKNLARMNKIIDNPFSQALITLAQLCHPNYGSV PTRDDVRALIRMVLKIDPVRSSILAGEILAQKPFAQFPDIEFPGLVERVGYYNIEKYE YIRNWIKEYREREKPLQIHEFFQKVFLEILLSNEVSEKDVIEAKKLIDSAESFVNVVS RFNRNASKDFLDVAKKGIKSAESIFELEEKLNGNFVLMSTPVAYLSSPLKSKVMILLS ISSNSWTPRSIKEITNIHVLTKTWNENDIYTEEMEEKNQKHYLAVLIRSLLKRCEDKL ITFESMLNANGYENNGILAEYFDEILTQ" misc_feature 58442..60082 /locus_tag="ClothDRAFT_1723" /note="Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210" /db_xref="CDD:30559" gene 60420..62651 /locus_tag="ClothDRAFT_1724" CDS 60420..62651 /locus_tag="ClothDRAFT_1724" /inference="protein motif:PFAM:PF00580" /note="PFAM: UvrD/REP helicase; KEGG: bas:BUsg574 ATP-dependent DNA helicase Rep" /codon_start=1 /transl_table=11 /product="UvrD/REP helicase" /protein_id="ZP_05429863.1" /db_xref="GI:256004889" /db_xref="InterPro:IPR000212" /db_xref="InterPro:IPR014016" /translation="MGLRKGQKELVERYRGGKCAIAAIPGGGKTHCLSLWAVEMITHG YHKPGKILIVTYMNSAVNNFKQRISAELQKRGINGSKDYFVSTIHGLCLQIIKEKPDL IIANEEFEVIDEVSKIHLISSAIDEWKRYNEREFQLYLDMENLSVSKMGDVYKSWHEK LCRIMLSAISDFKVKGITPSEAKERCKSLGRDSILAWASDIYEIYDRRLKIGGYLDFD DMLYNAKKMLETDEHLLEKYRKKYTFVCEDEAQDSNYIQNEILTLIANGNLLRVGDSN QAICGSFSSSDFTLFKNFCEAPDTTVYSITQSSRNTREIIDLANFFVKYVRESHPVHE CRDSLLPQYIEPVPEDDPRPNPVIDEYGIKAAVFESWEDEARGVVTQTIHMIKNHPDK TIAILVPTAWKMSLVVNILEARKVPFELLDNTSGERNKTLKKLGRIIDFLAVPEDGEK FSNMINECILTGDYDGPVFVDSEDETRTMGQRELLSEFIKKYPVEKILYPVGGIIETS DVPKELLKTKIWRDFTDSLDTVRQLLEFPNTVVEKLILFIAEKLRFDREERAIAQKVA GDVRYLMNQNPRWRLSDLAFELLSPKNMFNYFAGVVWDLKGFEPKPGVVTVATYHKSK GLEWDIVFLTGLNNADFPVLLDDRFMGEFWFLKEQYKNPQALIKSEMAKVFEGKIVKD SVLESKLETISERARLLYVGITRAKEYLFLSSYEQNKGKRVELPSKYFFELRRYIEEA GKT" misc_feature 60420..62621 /locus_tag="ClothDRAFT_1724" /note="Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210" /db_xref="CDD:30559" misc_feature 60465..>61694 /locus_tag="ClothDRAFT_1724" /note="UvrD/REP helicase; Region: UvrD-helicase; cl14126" /db_xref="CDD:187234" gene 62648..63481 /locus_tag="ClothDRAFT_1725" CDS 62648..63481 /locus_tag="ClothDRAFT_1725" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05429864.1" /db_xref="GI:256004890" /translation="MNNDLRFFNYFLFTQQSISTFEKCPLKFKKRYLEGLKWKNVISE EAKRRLEMGENFHLMARRYFLGIDTGLTKGIEGYEELSKWMEALESYFPKTDDALYLP EYKLRMAKGTLRLEANFDLLVIKKDGIEIWDWKTHGKKNPDKAENERLKSERLKGSLQ TMVYLFVLKEQAERVVQREVDCSNIRMFYWQPDPVRVLAEINYSDEMHEQFGQALRSK IDGILHYDYEDFDKELYKKNCPYCEFNWFCNNERVDFEAMEDDEDFLDQLDWDSIEEL R" gene 63482..64438 /locus_tag="ClothDRAFT_1726" CDS 63482..64438 /locus_tag="ClothDRAFT_1726" /inference="protein motif:PFAM:PF01368" /note="PFAM: phosphoesterase RecJ domain protein; KEGG: mxa:MXAN_4688 single-stranded-DNA-specific exonuclease RecJ" /codon_start=1 /transl_table=11 /product="phosphoesterase RecJ domain protein" /protein_id="ZP_05429865.1" /db_xref="GI:256004891" /db_xref="InterPro:IPR001667" /translation="MKVRVNILNKGVSIPQEVLDACGGDELVARIFYNRGYKNPETIR QMLNPELYVPTKPDEFPDMPRAVDRILRAADNEEKICVYGDYDVDGVTSTVTLVECLN FFTSKVVYHVPDRFTEGYGMNEEIVRKLAQDGVSLIITCDCGISNVREITLAKELGMD VVLTDHHTVPDELPPADAILNPKLLEEGHRARNISGCGMVYFLCLALLEKKGFPDRAE RFLDMLALSLIADVVSLNGENRYLLQKALPALFNTRRIGLRQLLEVAERNGKLENEED VAFQIAPRINAAGRMDTARLPVELFYVRTWKKHALWLRKLTH" misc_feature 63713..64168 /locus_tag="ClothDRAFT_1726" /note="DHH family; Region: DHH; pfam01368" /db_xref="CDD:144819" gene 64414..65751 /locus_tag="ClothDRAFT_1727" CDS 64414..65751 /locus_tag="ClothDRAFT_1727" /inference="protein motif:PFAM:PF02272" /note="PFAM: phosphoesterase DHHA1; KEGG: sat:SYN_02529 single-stranded DNA-specific exonuclease" /codon_start=1 /transl_table=11 /product="phosphoesterase DHHA1" /protein_id="ZP_05429866.1" /db_xref="GI:256004892" /db_xref="InterPro:IPR003156" /translation="MAEKIDSLNTERKRVQQSIVDEAVEMVETRKKNKTILVLYKEYW HHGIIGIAAGRICELYRKPAILFSLKEDGITAVGSARSIEEVNIYELIKECSGKLLKF GGHSQAAGLSIRKDDIEEFISQIEMEAENRYFIKDMVNVNADMELGIEDINEELYDRI QSAGPYGEGFEAPCFCIRNVIVLSDRMTEKKHHIMVLEDQKGNRIPAVKWFGEDESFE GRCFDVTCRIGRNNYSKDAGIQLTLEYMVESFGKFKKLFEGEIIDERKTTVENLLRKY PNAQIFYEGLQTACPVENTIDRFSVKNCKELVFLSTPANTEIFKEVIALANPEKVIIN FAVLSNYTFKGFVLNLLGLIKHIIKRRDGRAYIDELSLKLCVEENIVKAGLKYLGSSG MLNYTLSDDEQKVYLSEGKGVADRNAFMAKKNLFRRFGGKECLSAVYFKDGDR" misc_feature <64417..65136 /locus_tag="ClothDRAFT_1727" /note="single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644" /db_xref="CDD:161976" misc_feature 64597..64791 /locus_tag="ClothDRAFT_1727" /note="DHHA1 domain; Region: DHHA1; pfam02272" /db_xref="CDD:145431" gene 65870..66178 /locus_tag="ClothDRAFT_1728" CDS 65870..66178 /locus_tag="ClothDRAFT_1728" /inference="similar to AA sequence:KEGG:Spea_1412" /note="KEGG: spl:Spea_1412 glycosyl transferase family protein" /codon_start=1 /transl_table=11 /product="glycosyl transferase family protein" /protein_id="ZP_05429867.1" /db_xref="GI:256004893" /translation="MYDKPLVSVIIPTFNREKLLPKTIDSVINQTYENWELLIVDDKS TDDTKKVVMDYAKKDNRIKYLLNNGNKGPGAARNFGINNCNGKYIAFLDSDDQWLKNH " misc_feature 65894..>66175 /locus_tag="ClothDRAFT_1728" /note="Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761" /db_xref="CDD:132997" misc_feature order(65903..65905,65909..65911,65987..65989,66146..66148, 66152..66154) /locus_tag="ClothDRAFT_1728" /note="active site" /db_xref="CDD:132997" gene complement(66350..67411) /locus_tag="ClothDRAFT_1729" CDS complement(66350..67411) /locus_tag="ClothDRAFT_1729" /inference="protein motif:PFAM:PF00532" /note="PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: hso:HS_1032 DNA-binding transcriptional repressor PurR" /codon_start=1 /transl_table=11 /product="transcriptional regulator, LacI family" /protein_id="ZP_05429868.1" /db_xref="GI:256004894" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR001761" /translation="MNSKDIAKIVGVSRSTVSRVINNYPDIPQATREKVLKAIKEYNY YPNASARRLAGMKSSTLGIFIIDIKDNEKPHHVIENNEDLLYGNSYFSPFINAFIDQS NKAQYHVLVSTIYSSDELWKIQSAFYEKRIDGAVIIGSSSIDYSKIFEIMDKDSITVA VDLDMEKENTGTVMSVNINNYGGVSDAIDYLVELGHKDIAVITGDLNKLSGKIRFESF KDALLRHGLPLNNDFIAYGDFTENSGYEGMKKILASGKKPTAVFTSNDTMAIGAYRAI KEYGLKIPEDISVMGFDNSYISQYMSPPLTTVNVSLPEIAKCSIELLLDSINNKEIKN RQKTVNVQIVKRNSCKKIV" misc_feature complement(66356..67402) /locus_tag="ClothDRAFT_1729" /note="Transcriptional regulators [Transcription]; Region: PurR; COG1609" /db_xref="CDD:31797" misc_feature complement(67247..67402) /locus_tag="ClothDRAFT_1729" /note="Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392" /db_xref="CDD:143331" misc_feature complement(order(67250..67255,67259..67264,67271..67273, 67280..67282,67319..67321,67328..67333,67346..67348, 67355..67360,67364..67378,67400..67402)) /locus_tag="ClothDRAFT_1729" /note="DNA binding site" /db_xref="CDD:143331" misc_feature complement(67253..67282) /locus_tag="ClothDRAFT_1729" /note="domain linker motif; other site" /db_xref="CDD:143331" misc_feature complement(66380..67150) /locus_tag="ClothDRAFT_1729" /note="Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267" /db_xref="CDD:107262" misc_feature complement(order(66482..66484,66533..66535,66695..66697, 66770..66772,66878..66880,66926..66928,66995..66997, 67130..67132,67139..67144)) /locus_tag="ClothDRAFT_1729" /note="ligand binding site; other site" /db_xref="CDD:107262" misc_feature complement(order(66578..66583,66590..66592,66602..66604, 66686..66688,67019..67027,67034..67036,67043..67045, 67076..67078,67079..67093,67112..67117,67121..67126, 67133..67141)) /locus_tag="ClothDRAFT_1729" /note="dimerization interface; other site" /db_xref="CDD:107262" gene 67774..68778 /locus_tag="ClothDRAFT_1730" CDS 67774..68778 /locus_tag="ClothDRAFT_1730" /inference="protein motif:PFAM:PF00722" /note="PFAM: glycoside hydrolase family 16; cellulosome protein dockerin type I; KEGG: rhi:NGR_b18340 endo-1,3-1,4-beta-glycanase ExoK precursor" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 16" /protein_id="ZP_05429869.1" /db_xref="GI:256004895" /db_xref="InterPro:IPR000757" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR008263" /db_xref="InterPro:IPR008264" /translation="MKNRVISLLMASLLLVLSVIVAPFYKAEAATVVNTPFVAVFSNF DSSQWEKADWANGSVFNCVWKPSQVTFSNGKMILTLDREYGGSYPYKSGEYRTKSFFG YGYYEVRMKAAKNVGIVSSFFTYTGPSDNNPWDEIDIEFLGKDTTKVQFNWYKNGVGG NEYLHNLGFDASQDFHTYGFEWRPDYIDFYVDGKKVYRGTRNIPVTPGKIMMNLWPGI GVDEWLGRYDGRTPLQAEYEYVKYYPNGVPQDNPTPTPTIAPSTPTNPNLPLKGDVNG DGHVNSSDYSLFKRYLLRVIDRFPVGDQSVADVNRDGRIDSTDLTMLKRYLIRAIPSL " sig_peptide 67774..67857 /locus_tag="ClothDRAFT_1730" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.538 at residue 28" misc_feature 67882..68505 /locus_tag="ClothDRAFT_1730" /note="lichenase, member of glycosyl hydrolase family 16; Region: GH16_lichenase; cd02175" /db_xref="CDD:185684" misc_feature order(67933..67935,67939..67941,67951..67953,68053..68055, 68059..68061,68128..68130,68134..68136,68140..68142, 68146..68148,68173..68175,68179..68181,68185..68187, 68191..68193,68404..68406,68410..68412,68416..68418) /locus_tag="ClothDRAFT_1730" /note="active site" /db_xref="CDD:185684" misc_feature order(68044..68046,68128..68130,68134..68136,68140..68142, 68179..68181,68185..68187,68191..68193,68221..68223, 68227..68229,68263..68265,68410..68412,68416..68418) /locus_tag="ClothDRAFT_1730" /note="active site" /db_xref="CDD:185684" misc_feature order(68179..68181,68185..68187,68191..68193) /locus_tag="ClothDRAFT_1730" /note="catalytic residues; other site" /db_xref="CDD:185684" misc_feature 68590..68652 /locus_tag="ClothDRAFT_1730" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 68695..68754 /locus_tag="ClothDRAFT_1730" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" ORIGIN 1 aaatcaaaaa aaatatatta aagtgtgtgc tttttgggaa aaatagtaca atcagaccaa 61 ttactaatag aagaaggagg gaacacgctg tataaaaata cagctttgta aaaatatgat 121 ggatagaaaa gaaagaatac tggcgtttat gagggaggat gcatacaaac ctcttttatt 181 cagtgaattg gttactgtac tggacgtccc aaaaagcgac atcgggttgt ttgaaaacct 241 gctaaaggag ctggaggaag aagggctcat atttaagaac cgaaaaaaca ggtatggagt 301 tcctgaaaga atgaatcttg tatgcggata cctccaggga aatgagcatg gttatggatt 361 tttaattccc gatgacgaaa acatgaagga tatattcatt ccttccggcg gtctgaacgg 421 cgccatgcac aaagacaggg ttatagcaag gatcaataaa aaaggtatcg gagacaaaag 481 agccgagggt gaaataataa agattgtaaa aagggccaac aagaccgttg tcggcacgtt 541 tgaaagcagc aagtattttg gatttgtagt accggatgac ccgagaatat ccggggacat 601 ttttattccg aaggacgaga taaatggtgc aaaatcaggt cagaaagttg tggccgaaat 661 tgttgtatgg ccggaaaaaa gaagaaatgc cgagggaagg ataattgaaa taattggtga 721 caaagatgag ccgggttcgg acattctctc tattataaaa gcttacaact taagagagga 781 cttccctgag gaggtaataa gagaggcaaa atcaatcagc cagaccgtaa ccgaggatat 841 gataaaggga aggcgcgacc ttagggattt gaccatggtc accattgacg gcgaagatgc 901 caaggacctg gatgatgccg tttccattga aaggcttcct aacggaaact accgtttggg 961 ggttcatatt gccgatgtaa gctactatgt caaagagggc tcccctttgg ataaagaggc 1021 tttgaaaagg ggtaccagtg tttatctggt ggacagggtt attcccatgc ttccaaaaga 1081 actttcaaac ggtatttgca gccttaatcc caaagttgac aggcttgctt tcaccgtcat 1141 gatggagatt gacaaatccg gcagggttgt ggatcatgaa atatttgaaa gcgtaataaa 1201 tgttaatgag agaatgactt ataccgacgt ttacaagatt ctcgaggaga acgacgaagg 1261 gcttattgag cgctacaaat acctctgcga caccttccac acaatgaagg aactggctct 1321 tatattaaga aaaaagagga tggacagagg agccattgat tttaattttg acgaggcgaa 1381 aatagtgctt gacgaaaaag gtgtgccgat tgaggttaaa agatatgaga tgaccattgc 1441 caacaatata attgaagaat ttatgctggt gtgcaatgag acggtcgcag aacacttttt 1501 ctggacaaac acaccttttg tttacagaat ccatgaagat cccgatccgg ataaaattga 1561 ggccttcagt gagtttgtac acaacctggg atatacgctc aaaggtataa acaaaattca 1621 tcccaaggct ttgcaggatg ttctggagaa ggccagaggc acaaaagagg agaccataat 1681 aagcacggtt atgctgaggt ctttgcaaaa ggccaggtac agccacatca acagcggaca 1741 ttttggactt gccgcgaaat actactgcca ctttacatca cctatcagaa gatatccgga 1801 ccttattatt cacagaatta tgaaggaata tctgaaaggt actgtaaatc cggaaagaga 1861 agatttatta aacagcagac ttcctgaaat tgcaaagctt tgttctgaaa gggaacgggc 1921 tgcggaagag gccgaaaggg agaccgaaga gctgaagaaa gttgagttta tgaaaaagca 1981 tgaaggacaa gtgtttgaag gtataatatc aaatgtgacg tccttcggca tgtttgtgga 2041 attggaaaac actattgagg gcctggtaag gataagcagc ctggaggatg actattatgt 2101 gtataatgac aaaagttaca gcctgatagg tgaaagaagc agaaaggttt atcggatagg 2161 cgatgtggta aatgtcatgt tgattaaagc tgatgtggcc gcccgcagga ttgaatttac 2221 cattgttgac aaaaacaatg gtgaaaatga tgagaaggct ttagagtcag atggaaagga 2281 gaatggcaaa cctaaaagaa agcgcaggag aaaaacacct gatgaagccg tgcttcttca 2341 tgtgcagggt aaaaagaaaa agaagaaaac taaaaaagct aaagtataaa gggagagatt 2401 tgtattttac ttgtaagtgc atgcctaatt ggagtgaatt gtaaatataa tggaaaaaat 2461 aatttgaata aaaaggtaat gaagctttgt tcagaagaga ctctgatacc tgtatgtccc 2521 gagcagttgg ggggatgtcc cacgcctaga gttccttctg agatagcaga cggtgacggg 2581 gcggatgttt tggatggcaa aagcagggta atgaacaaaa acggggaaga tgtgacagaa 2641 tattttataa aaggggcgca agaggtacta aagattgcaa aaaccatggg cataaagaaa 2701 gcgatactga aagcaagaag cccgtcctgc ggatttggca gtatttatga cggtacgttt 2761 tcgggaaaaa ccaaaagagg caacggtgta acttcggaaa ttcttgtaag aaacggtgtt 2821 tcagttttga cggaggaaga tatattaacg aaagaagata tatgatgtgc ggcagtatga 2881 ttataaaaaa ctataaaaat gcaaagagaa tgaaaaaaag aaaatgaaaa agaggtataa 2941 aatacaggat gacgattatg aggaggtaaa atgcttttac ctcctcatta aagactatac 3001 caaaaagttt ttaatttctt cacagaattc atcacaattg tcagtgtgga cgtccactct 3061 gataggtttg cttaaatcaa ggctgaaaat acccattata gattttgcgt ccaccacata 3121 acgtcccgat gttaaatcaa tatcaaaatc gtatttattt actatattga caaaatcttt 3181 aacatcagtg atggacttaa gtgaaatatt aaatgatttc atataatttc cccctttgtg 3241 ttctttaggc attatttgct ccatggtaat atattaactt gtttgaagtt gcaagtcaat 3301 tgttatattg ctaaaattta cttagtattt tgtaactatt ttttcatatc aaaataaagt 3361 agaggagttt tacgcaaaca atgaaaaggg ctgcattcta tacgttaggc tgcaaagtaa 3421 atcagtatga gactgaggca atttccgaaa tgtttgaaaa agcgggctac aagatagtag 3481 actttgaaga tgaagccgat gtttatgtaa taaatacatg caccgttaca aatttgagtg 3541 accgaaagtc acggcaaatg ataaggagag caaaaagaaa caacgaaaat tccatagtta 3601 ttgtgatagg ctgttatgcc caaaccgctc ctgaggaagt aagcaaaatc gaaggagtaa 3661 acttggtcgt ggggaccaag gaccgaagca ggattttgga gtatcttaag gaattggaga 3721 cttccggcgg ccggcgaaat tacgtcgggg acataatgaa aacccgggaa tttgaggaat 3781 tgggtgttaa tgtatacaag gagcgtacaa gggctttcat taagatacag gaaggttgca 3841 atcagttttg cacatactgc attattccct atgcaagagg gcctgtaaga agccgctcgg 3901 aggagaatat actgaaggaa gtgtcaggac ttgcacacag tgggtataaa gaagtggtgc 3961 ttaccggaat acatgttgca tcttatggaa aagatataaa gaatacttct ttgattgata 4021 ttataagaaa agtacatgaa atagaaggaa tagaaagaat aaggcttggt tccatcgaac 4081 ctacgacggt gacggaagaa tttgtcagag cgataaaggg aatggaaaaa ttatgtccgc 4141 agtttcatat ttctcttcaa agcgggtgtg acagtacttt aaaaagaatg aaccgaaaat 4201 ataccactaa agagtattta aggtctgtgg agcttttgag ggaaaatttg aaggatgtgg 4261 ccgtgacaac tgatgttatg gttggctttc ccggggagac tgacgaggag ttcaatgaaa 4321 catgcaggtt tgtcgaaaaa gttctttttg caaggatgca tgtattcaaa tattcccgca 4381 ggaaaggcac gccggcggca tcttatcctg accaggttgc gccgcagaaa aaagaagaaa 4441 gaagccgcat attgattgag cttgcttccc gaatgacttt ggaatacaac aaaagtttca 4501 caggcagggt tttgccggtg ttgtttgaac aggaagtaaa aggaaaagaa ggatttatgg 4561 aagggcttac accgaattat ataagggttg aatgcaaagg tgataaagat attgagggtc 4621 aaattttaaa tgtgctttta agagaggcaa aagatgatta tattgtcgga gagattgtaa 4681 attgattttt tatattgctt gcaagttttt taaattttaa gtagactgcg agaataaaag 4741 atacaacata ataaaacaag gcgaattaat gtgaattgcg cttaaaaata ttgcataatt 4801 tatcctgttg tattactata tatatatacg cgttgtgtta cgatgttggg ttggtgctat 4861 ttatgattag tcctcatttg gacaggagag tggtcagtta tgtcaaacaa tgaaactatg 4921 atgtttaatg tcgaaaaaga aaaggttaat gaagccaggg agttgcttgt gtctgtatac 4981 aaagctttga aggaaaaggg ttacaatcct ataaaccaga ttgtaggtta tattctgtcg 5041 ggagatccaa cctacataac taatcatctg gatgccagaa gctctatcag aaaagtggaa 5101 agggacgagc ttttagagga aatattaagg tgctatcttg aagagtgtat cggcaaagaa 5161 ggctccgtat aattattata cggagttttt tataatattt caatttattt caattattag 5221 atataaaagt tgttaggctg gtgtagtaat tgaaatattg caaattgggt aatacgggtt 5281 tggaagtttc gaaactttgc tttggcggac ttataatcgg gcctcttcag gcaaatctcc 5341 ccccggagac tggagccgaa ataattttaa agtcttttga gcttggcgta aattttatcg 5401 atacggcaga gctttacggc acttattccc atatcggaaa ggcacttaaa aagacaaata 5461 aaaatatcgt ggttgcaacc aaatcctatg cctattctgc cgaaggagca aaagaaagtc 5521 tggaaaaagc cagaaaagaa atggatattg atgtgataga catttttatg cttcacgaac 5581 aggaaagcag gcttacctta aaaggacaca gagaggcttt ggaatattat atttccatga 5641 aagaaaaggg aataataaaa gcggttggag tatcaaccca caatgttgag gttgtggaag 5701 cctgttgtga gatgccggag gttgacgtaa tacatcccat agtaaacaag gcgggtattg 5761 gaataggaga cggtacaata gacgacatgt taaaggccgt tgaaaaggct tattcggtgg 5821 gaaaaggaat atacagcatg aagcctttgg gaggaggcaa cctgattaaa tcctataaag 5881 aagccatgga ttttgtactt aatattccgt atatacattc catagcggta ggtatgcagt 5941 caatagaaga ggttgttatg aatgtatgca tatttgaggg caaagaagta cctcaagatg 6001 tccaaaaaag ccttgagaac aaaaaaagac atcttcatat tgactggtgg tgcgaaggct 6061 gcggaaaatg cgtggaaaga tgcaagcaga aggctttgaa gttagttgac ggaaaagcaa 6121 aagtcgagga ggaaaaatgt gtgttgtgca gctactgtgc gtcggtatgt cctgtgtttg 6181 ccatcaaagt atcgtaaatt ataaaattat aaattttata aacttaaaac tgtaaaaatt 6241 tacagggtaa atttacgtgg cactgaacca aaaggattgc tgtgaaaatg actactataa 6301 aaagcggcgg aggtggctat gagggtactg gggattgatt acggagacag cagaatcggg 6361 attgctatta gcgacccgtt gggatggacg gctcaagcac ttgaaaccat aacctggagg 6421 tcggatgtcg aagttccgct aaaaaggata tctgaattgg tcgaagaata tggagtaaaa 6481 acggtcattg tcggctttcc caaaaacatg gacggcacag tgggggccag gggagaaaag 6541 acaatagagt ttattgacct gcttcagcaa agaataaaag atattgaagt gataaaatgg 6601 gatgagaggc tgactacggt tgccgccaac agaaccatgt atgaaatggg aataaaaaaa 6661 tcaaagaaaa agctggtagt ggatcaaatt gctgcagtat atattttaca aggatatctc 6721 gacagcaagg gaaaggtttt gtaattataa atattgaaaa attgaaaata atagttatat 6781 gtactggaat ttatagaata ttgtgatata atctatactt gataattaaa ataggaggaa 6841 tattttatga gtgaagaaag agacgatctt gtggtattaa ttgacgagaa tggcgaggaa 6901 actgagttcg aacatctgga tacaattgag tataacggaa acgaatatgt ggttcttttg 6961 ccggttgagc agactgaaga agaaaacgac gcggaggaag tggttatttt aagaattgaa 7021 caaggagagg acggagaaga cagttttgtg accgttgagg atgacgaaga actggacgct 7081 gtttttgaag aatttaagat gaggatggaa gaagagttcg aatttgaaga agaataaaaa 7141 aaggaggaca tccccgaatc tggtgttgaa aattcaggtt cggggatttg cttgtatgaa 7201 aaagaaaaat aaaattgttt tttgctatga tggaaattaa aaggattttg ctattttatg 7261 tagaaaataa accttgcaga tttactaaag ataatggggg attaaaatgt atcacaactt 7321 ttcaattaaa aaggcggtat tattgttggg aatattggcg cttgtaatgt tctctgtttc 7381 ctgcgggcgg agcgacaata cggaaaataa cccggatgca agcccggaac ccacggagga 7441 aaatgtgaat tttgattatg tggagcagcc aagtccggaa cccgaacaag aggtaaactt 7501 tgtttttccc gaaaaaggag taagacctta tgccgtaatg attgacaacc agggagaaaa 7561 atgtcttccg cagggaggat tgagccaggc ccaagttatt tatgaggtaa ttgttgaggg 7621 tggcataaca aggttcatgc ctgtgttctg gggtcagaaa acggaactca tagggcctgt 7681 gagaagtgcg cgccactatt tccttgacta tgcattggaa catgacgcaa tttatgtaca 7741 tatcggatgg agtcctatgg caatggcgga tatacccaag cttggggtaa acaatataaa 7801 cggtgcttac ggagttttct gggacattac aaacgacaaa tcaaactggc aggatactta 7861 cacgtcaatg gaaaaactgg aggaatacgc aaaaaaggtt aattacagaa ctactacgga 7921 caaagaaatg gtgtttaaat atcataacag ggaccaggag cttgaaggag gcaaaaaggc 7981 tgagaagata aacctctcat attctggcga gtacaaatcc tattatgaat atgatgccga 8041 caaaaagctc tatctgagat tcagaaacgg aaagccccat attgaaaggc agactggaga 8101 gcagctcacc acaaagaaca ttattataca gaaagtcaga aattatgaca taaaaggtga 8161 ccagtacggc aggcaaaatc ttgatacagt tggcagcgga gaaggctatt atatcacaaa 8221 cggaaagtgc attgaaatta agtggtcgaa agcttccaga acggaaaaga caaaatattt 8281 ggacggcgac ggcaaagaaa tagttttaaa tcccggtcag acatgggttc agatattccc 8341 tgtatcgggt aaaattgaaa tagaataagt cttaaatata agcaagcagc tgttatgccc 8401 ataatgctcc tatagattga tgttgataaa aaagagcata ttggttatta ttaatatata 8461 tgtgtgttta ataaaattat gtctgcagtg tttaaaattt tgaatagggt ataaaagttg 8521 aagcagattt tattttgttt tgacgttgta tatacaaaat acatatttgg aattatatat 8581 ttattcgttt gtttttggag gttaagttgg gtattagagt aagtgacaga atattacaga 8641 gtgtggaaaa accatcaaga tatacgggca atgaatggaa cagcgtaaaa aaagatttaa 8701 agggaataga tataagattt gctttctgtt tccctgatgt ttatgaagtt gggatgtctc 8761 atcttggcat gaagattttg tatcaccttc tcaacgagag ggaggatact tactgtgaaa 8821 gagtttttgc tccatgggtt gacatggaag caaagatgag agagcacaac atacctcttt 8881 ttgcccttga gacccatgac cccataaggg aatttgattt tataggtttt actcttcagt 8941 atgagatgag ttatacaaac ataataaata tgcttgacct tgcgggggtg cctgttttaa 9001 gcggtgagag gacgaaagag catccctttg tctgtgccgg cggtccttgt gcatacaatc 9061 cggagccttt ggcagacttt atagactttt ttatgatggg tgaaggcgag gaaataatca 9121 acgaagtgat ggatgtgtat gtacaatgga agaagaaaaa tttgccaagg gaagagtttt 9181 tgcgctgcat atcgtcaatt gagggagtgt atgtccctca attctatgat gtaaaataca 9241 acgacgatgg caccataagc tcttttttgc cgataaggga tgagtatccc aaaaaaataa 9301 gaaaaaggat tataaaggac ctggacaagg tctttttccc tgaaaaaata gtagttccct 9361 ttacgggaat cgttcatgac aggataatgg ttgagttgtt ccggggctgt atcaggggat 9421 gcagattctg tcaggcaggt tttatttaca ggcctgtaag ggaaagatcg gcggacaggc 9481 ttttggagat atcccgaaag cttgaggaaa gcacgggtta tgaggagatt tcacttactt 9541 ccttaagtac cagtgactat acggcgctga aagaactaac cgacggactg atttgtgaga 9601 tggagccgaa aaaagtgaat ctttcgcttc cgtctctgag ggtggattcc ttttctcttg 9661 aacttatgga aaaggcccag aaagttcgaa aaagcggtct tacttttgca ccggaagcgg 9721 gtacccagag gcttcgcaat gttataaaca agggtgtaac cgaagaagac ctcataaaat 9781 ctgtttctct ggcttttgaa ggcggctgga gcggagtaaa gctttacttt atgctggggc 9841 ttccgacgga aagctatgaa gatattgagg gtatagcgga acttggacat aaagttgttg 9901 aagcatataa aaatacgcca aaagacaaaa agggcaaagg acttagtgtc actatcagca 9961 catcgtcctt tgttccaaag ccttttacgc cttttcagtg ggagccgcag gacagtatcg 10021 agactttgag ggaaaaacag attttcctga aaagcaaaat aaaaagcaag agcatcaagt 10081 acaactggca tgaccctgaa ttgagctttt tggaggcaat ttttgcccgc ggagacagaa 10141 aactgggtaa agtgctgctt aaggcttttg agaaaggctg caagtttgac agttggggag 10201 agcacttcaa atttgacaaa tggatggagg ctttccgtga atgcggaatt gacccttcat 10261 tctatgccaa caggaaaagg tcatatggtg agattttgcc ttgggatcat attgatgtgg 10321 gagtgtcgaa gaaatttttg gaaagagaac atgaaaaggc attaaaagaa gaagttactc 10381 caaattgcag agcaaactgt tccggatgcg gagccaccgt gtttgagggg ggaatttgtg 10441 ttgagtagta tcagagtgaa attcgttcgg ggggaagaag tcaaatacat ttcccatttg 10501 gatttgatga agatgtttga aagagcggta aggcgttcaa atattcccat agcgtattcc 10561 cagggattta atcctcaccc tcatatagtg tttgggcttc cgctttcggt gggagtgacc 10621 agcgactccg agtatgctga ttttgagctt gaaaaggata tgaagcccga agagtttgca 10681 caaagactta accagaatct tcctgaaggc gtaaaaattg ttgaggcaaa aaagaacaat 10741 acaaattcca atatcatggc tcaagtggcg ggagcattat atgaagtatt ggttttggcg 10801 gacggaaaag ttgaaataga ggatttgaaa agcaaacttt cgaagtttct cgagaataag 10861 gaaatattta cagaaaaaga atctaaagga aaaataaagt ccgtagacat acgtcccatg 10921 atatataatg ttgctgtaac tactgtcaag aatacggaag ctggagtttt ggagagtacc 10981 aaaactgatt ttaccgaaga cggatgtaaa aatttgtgga ttttaaaata tgttgaaaaa 11041 cttaaggctg aagacgattt gtttaaacaa acggacgaat cggctgtttt ctgttttaca 11101 atgctgcttg ccgcaggaag tatggcaaat ttgaaaccgg agtttgtaat tgcggctttt 11161 ggcagatatt caggcattaa ttttgagata ttaaaaattc atcgttccgg tctttttacg 11221 aaaaacaaag acaacctgac tgatcctttg gggggtcgtg tattattatc tgtatgaggt 11281 ggtagaatgg ttagtgagat tgtggtagat gtggggatta atgaaaaaag agtggctcct 11341 gttggaagac agggaactgg ttgaattatt tatagagaga aatgattgtg aaagacttgt 11401 gggcaatatt tacagaggca gagtggaaag tgtcctgcct ggaatgcagg cggcttttat 11461 agatatcgga tatgaaaaga atgctttttt gtatgtaggt gatgccatac ctcagaaaga 11521 attttccgaa gatgatgaag aaatctatag cgatgttaag agttacaata tcgaagagat 11581 attaagaccc ggtcaggaaa taacggtaca ggtaaccaaa gaacccatag gaacaaaagg 11641 cccaagggta actacccata taacgttgcc gggaaggcag atggtgcttc ttcccaacgc 11701 cgattacatt ggcatttcta ggagaattga ggatgaggag gaacgggcaa agctaagaaa 11761 aatagccgaa aagatcaaac caaagaatat gggaattatt gtaaggactg tttcggaagg 11821 caaacgggaa gaagatttta aaaatgattt gaattttttg gtcaaacttt gggcaaaaat 11881 aaaacaaaga gaacagagcg gaccggttcc caggtgtttg cacaaagatt tgagtgtaat 11941 ttacagagca gtcagggaca tctttacatg gaacattgac aggtttgtta ttaatgaccg 12001 gcaggagtac aataaggttc ttgagcttgt tgaaatgatt tcgccggctt tgaaaatgag 12061 agtggagtat ttcaacaaaa atattgattt gtttgagtac taccagattg acagcatgat 12121 acagaaggca ttggccaaaa aggtctggtt aaaatgcgga ggatatattg taatcgagag 12181 aacggaagct cttacggtta ttgatgtgaa caccgggaag tatgtggggg taaacaatct 12241 cgaagacacc gttttaagga ccaatcttga tgcggtcaaa gaaatcggga aacaattgag 12301 gctaagagac atcggaggaa taattattat tgattttatc gacatgcatg atccggaaca 12361 tcaaaaacag gtactggaag ctttaaagca ggtattgaaa aaggatcgca ccaaaaccac 12421 tgttgtcggc atgaccggtc ttggccttat tgagatgacg aggaaaaagg ttagggaagg 12481 cttggagtca atgatgcttc aggattgtcc ttattgtgaa ggaaggggga aaatactttc 12541 gcccgagtct gtggcaagaa atgttgagaa agagataagc aaatacttta caaaaacaat 12601 agcaaatgct atcatggttg aggttcatcc tactgtggcc gaggtgttga gaggagaaga 12661 caacgacaac cttgcaagaa ttcagaatct gtttaacaaa aaagtcataa taaaaccctc 12721 ggcggaagtg ggacatgagg aagtgaaaat aaaagaagtt gacatagata cacttgtatg 12781 atacaatatt tcggtggccg ctcggctcag gtttggtaaa tgcaagcaac agtttgcttt 12841 gttgctgcta ccttttgccg gcgagactgg gtagggaggt gttttggatg tacgctgtga 12901 ttgaaacagg cggaaaacag tacaaggttc aggaaggtga cgtgctcttt attgagaagc 12961 ttgcaaatga agaaggttcc acagtcactt tcgacaaagt tgtggccgtt tcaaaggatg 13021 acaaggtaag ctttggcact ccttttgtaa gcaatgcgtc tgttactgca aaagtgttgt 13081 gccatggcaa gggcaaaaag attattgttt tcaagtataa gcccaagaag ggttacagaa 13141 ggaaacaggg ccacagacag ccttatacga agatacagat tgaaaagata aatgcataag 13201 gtaatagttc aatgattaaa gttgaagtaa tcagggatag tgagcgtttc atacgtgaac 13261 ttaaaatcaa ggggcatgca ggctacggca ggagcggaaa agacatagtg tgcgcggctg 13321 tgtcggctct tgcatacact gcggcaggag ctcttgaaga gctggccggt ataaaggggt 13381 acaacgaaag gaacggatat atgagatgta ccgttccgaa ggatataccg gaagacaaaa 13441 aagaaatggt gagaactatc cttgaaactg tggtaatagg cttaaaacag gttgaacttg 13501 gatatggaaa atatgtatcg gttttggata aggaggtgtt gaccgatgat taaggcaaat 13561 ttgcaattgt ttgcccacaa aaaaggagtg ggtagtacaa gaaacggtcg tgacagtgag 13621 tcgaaaagac ttggtgtaaa aagaggcgac ggtcagtttg ttaaggccgg gaacattttg 13681 gttaggcaga gaggtacaaa aatacatccc ggtttgaatg tcggaaaagg caaggacgat 13741 accctctttg ctttggtaga cggaagagtg aagttctcaa gattgggtaa agacagaaaa 13801 caggtaagta ttattcctgc ataaaaaata aaattataaa tcccggtttt accgggattt 13861 aattttatga tttgtgcaat actaaggaat agaaacacat ttattatacg tatgccatgg 13921 agttgaaaca caatgtttgt tgacagagcg aggatatata taaaagccgg ggacggcgga 13981 gacggcgcga tatcctttca cagggaaaag tacataagca agggcggccc ggacggcgga 14041 gacggcggaa aaggcgggga tgtaatcttt gttgtggatg aaggattaag aacgcttcag 14101 gacttcagat ataaaacccg ctacagagcc gaagacgggc aaaacggcgg cagctccaac 14161 tgttcaggca gaagcgggga agatttgata ataaaggtcc ctccgggaac tttggtaaag 14221 gatgagcaaa caggcaggat tctcgccgac cttgtaaagc ccggtaagaa agttgtaatt 14281 gcaaaaggcg gcaagggtgg agccggaaat cagcattttg cgactccgac aaggcaggtg 14341 ccaagttttg caaaaccggg ggagccggga gaagagctgt gggtgatatt ggagcttaaa 14401 ctcctggcag acgtgggact gataggtttt cccaatgtgg gcaaatccac aattctttca 14461 atggttacgg ctgcccagcc caagattgca aattaccatt ttacaacaat aaaccccaat 14521 ttgggtgttg taaacattga cgccgagaac gcctttgtaa tggcagacat accgggactt 14581 attgaaggtg cgcatcaagg cgtgggattg ggtcatgaat ttttaaaaca tatagaaaga 14641 acaaagcttc ttattcatgt ggtggatatt tcaggatccg agggaagaga ccctgtccag 14701 gattttgaag taataaatga agaacttaaa aaatataacc ctgtactttg tgaaaggccc 14761 cagattattg cagcaaacaa gatggatgtc acgggagcgg aggaaaatct tgaaaaattc 14821 aggaaggtta tcgaaccaag aggatacaaa attttccctg tatccgcggc atccaacaaa 14881 ggacttaagg aattgatata ttatgccgca caaaaactta aggagctgcc cgataccgtt 14941 cttgtaaatg accaggacaa tgaagttgta tatacggcgg ttgaagagga accctttaat 15001 atcaggaagg aaaatggtgt ttttgtggtt gaaggaagct gggtacaaag gctggtaaga 15061 tcagtgaact ttgacaatta tgaatctctg cagtatttcc aaagagccat aaggaggaaa 15121 ggaattgttg acgccctgga aagtatggga attaatgaag gggataccgt aagaatgtat 15181 gacctggaat ttgaatattt tagataaaat ttattcaaat atcctgtaat tgtttgcctt 15241 aacaatgtat acaaaaagat ttgctggaca gatatgcact atatgttgta aaatataata 15301 tataataact taatacaagc atgataaaaa acggaggggc attagtaagt tttatggagt 15361 gttttaattg tggaaactgt aaaaccggca gtgcggcata ttattgcttg atgaaggatg 15421 actttgtgct aaaccaggaa gcaacatccc aggttattga aaaaacgagg gctgggtgga 15481 agaaaggaca tccgaaatat gaagttcaaa gaagaaaaag ccggaaagaa gtcgaagcat 15541 actaagacat gaatggggat agggtcaact atccccatta ttttaaattt tagtttttaa 15601 attagttttc agaaaaacat tgggcaagga gagttgatat gcttacaggt aagcaaagaa 15661 gctatttaag aagtttggca aacagcatcg aacccatctt tcagattggc aaaggcggaa 15721 taaatgacaa tatgataaag cagtttaacg aagctttgga ggcaagggag cttataaaag 15781 ttgcggtgct taaaaacgcc atggttgata caaaggaagt gtgtcatgaa gtggcaagtc 15841 ttgtgggagc cgaagtggtc caggtgatag gcaataaatt tgttttgtac aaagaatcaa 15901 aagagaacaa ggtaatagag cttccgtaat atttcccata aaattttagg tgtttttggt 15961 atgaaaaagt tatgtaaaaa gagcccggtt aaagggctca acataccaac aaagtcatga 16021 attttctccg gtgtttttaa ttctgtcttt tataaggctt tcaataattt cactgtatat 16081 ttcctgggaa tgttttttcc agttttcaca aatccttcgg gcatcatttt tcgttcccac 16141 tgtaaccttt aaatcgataa ggttgaaatt gtcctcccgg acctgacacg agacggtgaa 16201 ttcgttttct ccgcttaagg tatattcagc tgaaataaag gtttcgtttc tgatgttgtt 16261 ccttatgttg gatatactgt tgtcaataag gctttttata ccctgcggta tatggccggt 16321 aaagtagctt aaggtttgtt tccccaaagg agtaatggtg taaaacgctt tattgtcaat 16381 atttttatac aatagatagt tgctggtgca aagttcattg agaagctgct gaagcataaa 16441 ataattcata aatttatttt ccagaatgat ttttgttatc tgcagattgc tgatgggtat 16501 gtttacttta tcaataatat aaagcagaat cagtttgttc tctgcaagtt ctttattgct 16561 gacgatactc atggcaataa tcattccttt cgctcagctt aatttggctc tcaagttaaa 16621 aatcaaatca taaatttatc acgtttctta gtatgtagtt ttgagtgtat tataacatag 16681 tgaaggggaa ttgtgccata ttgcccgaag acaaatcaaa ttttgattat atttggctta 16741 tataaacttg ccgataaata cgtatatata aacatatatg gatggaataa ttgttatgta 16801 tgttttataa tattctaatg tgtgttgttc ttataaaata ttattatttt taaaaaatgg 16861 gtgtgaggag ttttttgaaa tgaataattt tactaaaatt caagataaat taatggaaat 16921 gggtgcatcc tttgtaggct gttccgatgt tgaggcatac cttccggaaa atcttaaaaa 16981 ggttaaatat gctataactg tcggagtaag actgtccgat tttattattg accaaataag 17041 cgacaagcct acctatactt attttcacca ttacagggcg gttaatacgt tgatagacca 17101 gataacttta aggggtcaga tagagattca gaatatggga tatagtgcca tggcggtacc 17161 tgcctcccag actgtcaacg atctggaaga cagatattca ggcgttttcc agcacaagac 17221 cgccgccgta aaagcgggtc tgggctggat agggaaaaac ggtttgttta tcagcactaa 17281 atatggtcca agagtaaggt tgggaacaat acttacggac atggaacttc cgattggttc 17341 ccacgttgtc cgggacggct gtggcagctg cagaatttgc gttgacagct gtccggcaat 17401 ggctttgacg ggtaacagct ggtttgccgg ctgtgacagg agccatattg ttgatgccca 17461 ggcgtgcagt gaatatatga acaggaattt caagcacata ggcaggggct ctgtatgtgg 17521 tatttgtatc agagtgtgtc ctaaaggatt ttcaaaataa gagtatttga tttttacgag 17581 gacaggagat ataaaaaatg aaaaaagtgc ttcttgttaa cgacagtaag ttcgaaagca 17641 tgattttgaa agatatgttg gtaagtatag gatatattgc cggtattgcg gatgaatatg 17701 atgcaattga aaaggtacag gacatgcgtc ctgattatat tattataaac cgcgtgatga 17761 aagaaatata tggtgacgaa ttagcttcaa aaataaaagc ccgttttccg gagataaaat 17821 gtattttgtc atcttgtgac tcaataagta tagatgatta caagaacagc ggaattgacg 17881 cggtaataag aacacctgtt gaccaataca ggcttaaggc tgtattgaaa aatgtggaat 17941 atcttaaaaa tgacataaga aaataatgta tgtttattgt ttttgccctg tgagaataat 18001 aaacgcaggg tgataattat gggttacgtc tttttttatc tttcactgtt cggagtattg 18061 atcagtctga ttatatgtct ttattttaaa cctttggatt tcagaaaagc cgttataggt 18121 attatgaccg ttgcatattc gatgatttat gaaacggttt taagcggtta tttaagtctt 18181 tattattatc ttaatccccg ggattctgtt atttatattg tgatgtcggc aattttgctg 18241 tatccgtctt tgaatattat gtatacaatg tttttaccaa aagataagaa ggctgtactg 18301 ggatacacga ttgcatggat ggcagctatg atgatttttg agtatttcag tgtcatgttt 18361 ggaacggtgg tgtttacagg atggaccccc tttccttggt ctgtggttac ttatgtggta 18421 acctatcttt gggtgtatct gacataccgg tatttaagca aaaagagact tacgggaaaa 18481 cttctgtaag tgtttgaagt ttattgtttt ttacgattct ccaatttttc ttttaaccgg 18541 tatatccggg caaagttttt tactacgtca aaccttgtgt tgtataaaag atgacgaatt 18601 cccggaaacc ctatggaagc cagcagagaa tcataagtat cgttgtcggc ggtattaaag 18661 gctttcctca tttgataaag ctgttggttg tgctttgtca cacgtttaag aagcctttca 18721 taatcatctc cgtttgcaat ggaccgggcg gccatgactc ccatttctat ggagtttaac 18781 tggccaaagc ctaaaaacgg atctattgca ccgccggcat ttccgacaaa atatatgttg 18841 tccactttgt gaggataggc aaaccctgtg tcatgagcct gcttgaattc ttccacaatg 18901 gtgtaattta tattttcgta gtccaaaaag gccttccaat aatggtcaat ttctttttca 18961 tttacgtcgg ttactaccaa tatgactgaa gcctttttac tgttaaaagg tgaaagataa 19021 gcatatccgt ttttgcaata atctttgttg atccacatga taagattgtt tggatcgaaa 19081 tctcccaata aaaccgcacc tcttatgtat gttttgattg taggatacca acatcccaat 19141 tgattggtaa acacggtgtt tccgtttgca acaaccacgt agtcaaattc ctttgccaaa 19201 ggatcaatgt ctccgtaagt attaaagttt attttggagg ttttaagatg ggaaaaaagc 19261 tgcatgggca gtgaatcttt atcccgtcct cttttcagga aaaaaccaaa attaccctta 19321 atcactgttt tcctgtttgg agaatagtgt gtaagggtgt taacggtgtt gacgggggtt 19381 atgcttatgt caaaattttt cttaatgtat tttattgcat cctttattgg cctgtgctga 19441 atttccagaa ggaccgaaat atggctgtat tgatccccta tatatccgtt tctgtggaat 19501 attaccgggc tgataccgtg cctttccagt tcgtgagcgc aagaaaggcc ggacagtcct 19561 ccgccgatta ttgcgacttt cacgtcaaat acctccgaat ctttttaaaa atatcagcca 19621 cgcggatacc agcaagccgt ttgcaaaagt caggacggtg tacagaaaaa tattcacctg 19681 gcaacatcct cctttttgtc cagcacaact attgaaaacc agcttagtac tatcattaca 19741 catacattaa taaaaagact gctggtaaag tgccagttgg tgtaagcaag attgccgctt 19801 aaaatcagta aaatttcctg taggaaaaaa agtgccgaaa ttgcaaatat atttactatt 19861 ctaagccatc tcttttttgg atggagctgg gaaaaaaggg ttcctacggt gaatacaggt 19921 cctgcggtaa agaaaaggga agaacccatt atactgatta caggttcgtt cactgtatat 19981 aatccctgat taatggcctg ggtgtctgtt acaagttgca ggactgcagc cagaattccg 20041 ccccatatgt tccttttcag ttgacgaaaa tcaataaaga caaagaatat tatccaactc 20101 attacaaaca atataaccca ttccataacg aaattatctc cttgcaagta attattgatt 20161 aaagtttgtg cgctaaattc tgggttttaa agggaacagt ttggagataa ttccctctga 20221 tgattgaatc ctgtctattt tttgctggag atttactata tctctcattt catcgtccct 20281 aagctgggtg aaaacctgtc ttgcttcagg atttttaata taaatcaggc attcgttgta 20341 aaacatctca tttgcaattt tagattgcag taaatcttgt aaaatagcac tctgctccaa 20401 ataaatcacc atgctttctt tttagtatca gtgaccgatt attgcgattt atcgattgac 20461 aacaaaatca ttttgtcgtt tatcattttt atatgatcac gggaagtctg tgaaaagtcc 20521 ctcaggatat tttttaattc tttatctttt gtaatttggt aataatgttc atattttttt 20581 aacaaaagct cttctctgtt tattgcaccg gtgaatgcta tatttaaaat gtattgttga 20641 gactgtcttt ccataaactc ctccgaaaga gcgaaattca attaatctat aaatattttt 20701 gtcttttttg caaatattat tcttatgaat taataaggaa gcaatgtaaa agtaatacgg 20761 attatgaaac aatagtaatc tgcaaagatt aacataaatt ttatgccgag gtggagattt 20821 tatgaagatt gccataattg gtgcaggact ggccgggctg tcctgtgctt ttgaattgga 20881 gagaaacggc ataacgccgg ttatttttga gaaaagatct tttataggag aaaactacat 20941 gtttcccagt acaactctaa gactgtttga caggggtttt aataatcccg taaaatatct 21001 caaaaaaaaa tacgacctga gtcttatacc tttttcccct ttaagagaaa taacaatgaa 21061 gggacccaca aaagaaggaa ccgtaagcgg aaaattggga tatgtattca tgagaggaga 21121 cgaaaaagaa tccctggaaa atcagattgc aaagcatatc aggactccca tgcattttga 21181 cacatatata aatcttgagg atgtaaaaaa tgattttgat tatattattg tcgcgaccgg 21241 cgatgaaacc gttgcgaacc ggcttggagt atggcacaca acgacaactg tttatacaag 21301 ggttgctctt gtattgggaa atttcaaagt gggttgtgca aaaatgtggg tcaaccggga 21361 ttatgacaaa gcgtgctacg catttttgtc tccccatagt aaaaaaagtg cgagattgct 21421 tttatctgtc aatgatatat caccccatga atttgactat tactggaata attttgtaag 21481 gcttgaggaa gtgaaatata aaataaatga aaccagggac attgtaacaa gacttggata 21541 cgtatccact gcaaaagtgg gaaatgttta tttgaccgga aatgccgcag ggcttattga 21601 tgattttttg ggttttggcg ccattaacgc cattgaaagc ggaattcttg cggcaaaggc 21661 aatcataaaa ggaaaagact acaatgaaat ggtaaaatct ataaaaaatc atgtagccgg 21721 cattcatgaa cttagaaaaa tgataaacga atttgacaat gatgattatg accggcttat 21781 aaaaattttg accatgcctg ttataaaacg gattatttac aacaatcctc tggcaaaggt 21841 ccaaagtatt acgtctgcgg caaaagagtt caacaacatg aagcataaaa ggcagcggcg 21901 tttttccaaa agctagccgc tgtatgtatg gtcagggagg tttgagaaat ttgcaggcaa 21961 taactaatac ttgatttttt gctttggatg ttttagtcta tatatgttta aagttgtttt 22021 tcaatattga ataaattaaa aacggggata ttttttgatg aaataacgta atatgatgta 22081 taagtgaggt tatttatatg aagatcagta tagaaagagc aagaagcaat atttttacca 22141 atacaagacc gcagctggat gtgtttggaa taatttatac tgtgcttttt gtatgttcca 22201 ttgtatttaa aggggtgttt ctccaatttc agaaccaaat taatttcaaa cctctttttt 22261 caaccacaaa tattttcatg tttgttgctt caatgtcttt tacattggta ctggcggctt 22321 tgttgaccgt ttttcacaca aagagaagag tgttgttttt catatccaac attttaatgt 22381 cggttttgct tctttctgat gctctgtatt tgcgctatta caacacgata ataacaatac 22441 cggtaattta taatgcccga tatttggggc cggtcagaga gagtatcatg agtcttttca 22501 ggtttagcga catattctat tttttggata ttcctgtttt tgcagtaatg tcgtttatat 22561 tttccaaacg ggctgaacag aacaagcttc cgttgctgaa aagatgcgta gtggccgcag 22621 tgctgatggt agtagctttt ggctctttta aaatagcata cagcaaaaat gacatgtccg 22681 agtacgacaa caattatatt gtgaagaact ttggcatagg ttatttccac tattatgatg 22741 tgaaaaaata tttaaaggaa aattatctta gggataaaaa acttagaact gaggagaaaa 22801 atgaactgac atccttcttt gaagaaaaaa acaaggaaaa agccgcactt tccaatagat 22861 ttaagggaat agcaaaaggg aaaaacctta ttattgttca gatggaggct cttcagcatt 22921 ttgttatcaa cagcaaaatg aacggcaggg aaataactcc caacttaaac aagcttgtaa 22981 aggaaagtct gtattttgac aatatctatg tgcaggtggc agggggtaat acgtcggatg 23041 ccgagtttat gaccaatact tcattgtacc ctgcaaaaga aggtgctgcc tattttagat 23101 ttgcaacaaa cgagtataac accattccca aggaattaaa gaaagaaggc tataattcct 23161 acgctttgca tgcatacgga cctgcattct ggaacagaac cgaaatgtac aaagctatag 23221 gatttgatac ttttataagc tctaacgact atgttatgga cgaatatata ggctggggag 23281 gctgggcgtt aagtgacgat tcgtttttca gacagtctct ggagaaaatt gatgtcacca 23341 aaccgttcta ttcatttttc ataactcttt ccggtcatca tccttattcc tattttgagg 23401 ataaacaaac ctttgatgtc ggaaaatatg acaggactta tttcggcaac tatattaagg 23461 ctcagaacta tgctgatgcc gctcttggcc gttttataga aaggcttaaa gaaatgggtc 23521 tttatgagaa cagccttatt gtcatctacg gcgaccatac aggtcttccc aagactcagg 23581 caaaagaact tctggaattt ttgggagtgg acgacaacaa ggttgactgg ataaagcttc 23641 aaaagatacc tttgctgata cattgtccgg gggtgaaagg agaaaccatt agcaccaccg 23701 gcggacaggt ggatatattc ccgatgattg ccaatatgat gggatttgaa aactattatg 23761 cgttgggcaa agacctgctg aacaccgaaa aaggttatgc ggtgctgaga aacggttcag 23821 tgctcacgga tgactattac tactgcagtg aggatgatac cgtttatgat ttgagaagcg 23881 gtgaggttct tgacaagaag gactatgaag atgagataca aaaatatcaa aaagaacttc 23941 aaatatccga cataattctg gaaaaagatg cactgcggaa gttgaaataa agtgaaaaaa 24001 atatgaaaat gcaagaaaag tgaaattcag gtgtaatttg tgtttgaatt gtgtcgtata 24061 tgtttatata attaaagtat attatttaat gtattgttta aaatatattg tttaaataat 24121 aagcataaaa atatgaaagc ccaatgcata aacaacgaag gagagtattt aaaatggcat 24181 ctttctttaa gtcaagagtt gcaagaattc ttcccttaat agctttgtct ctttctctgc 24241 tgtttgcagg atgtaacacc agtcccaaat tgaatggcga tttgaagtca ccggttccca 24301 ataccgccgg acaggatgcg ggacaggaag gtggttcttt ggcaacaccg actccaacac 24361 cgacacctga gccaacgcct acaattgatc ttcaaagtgt caagcctaat gaggctggca 24421 aaataatggt tgttatgttc cataattttg ttgagtcttt tactcctaag agttatgata 24481 agggtgaata caccactact ttcagtgagt ttgaaaagct gcttcaagac ttgtatgaca 24541 gaggttacag gcttatcagc atgagtgatt atttaaataa caatatttca gtgcctgcag 24601 gatgcatacc gataatattt acatttgacg acggaacatc gggacagttt aatttggttg 24661 aagaaaacgg aactctcaaa gtaaataaaa aatctgccgt aggaattatg gaagagtttt 24721 atgagaagca tcctgatttc gggcttaaag gcactttcta tgtgaacctt ggcaacagca 24781 cttttgaggg tgcgggaact ttgcaacaga ggcttcaata tttggttgac aaaggatttg 24841 aaattgggaa ccatacttat acccatataa atctgaaaga taccacaagt gctcaaaaaa 24901 tacaggaaga gattgctaaa aaccaaagga ctattgctga gcttataccc ggatataaaa 24961 tgactacttt ttctcttccg tacggacttc catctgtaga aggcctgcat agctatgtta 25021 taaaaggtag ttatgaaggg gtggaatacg aacatgcggc aattatggag gtaggctggg 25081 atccggccca ttctccggta tcaaaagatt ttaaccccct ctcgacccac agggttagag 25141 cttcgggaat taatcctgta gattgcgacc tggcatggtg gcttaaaaat ttatccaggg 25201 aagagcagta tataagtgac ggagatccca ataccgttac agttcctaag aaaaatgaag 25261 acaaagtaga caaggataag ctaaaggaca aaaagctcgt tatatattaa gctttgaaat 25321 acgattttaa tgaatatgga gcaaaaggga cttggcggtc ccttttgtat tattttttct 25381 tattaagtat tcaattacta tttttatgat ttgcattaaa agtaatactg tattataatt 25441 aatgtgtata atattagata tgtaacatag aatttcccat aacaagttag ccctacaaaa 25501 aattaataat tttataaaga aataattttt gtttttgcag caataactgc attattttgt 25561 actattatta tttaacaggg agtgtttcaa atggagaagg ttcaatccaa tgctaattcc 25621 aaaaaagaag gaaccaaaaa agagggaagg aaagttcaga cggatgcgga cgtaaagaaa 25681 aaggctgtaa aacttgttat ttctcattta aagaaaaaaa tagccaaaga gttttccggt 25741 tctgagcttg tccgtcaatg ggttgaagag atggaaaaac tattggaaaa agaagaattt 25801 gagttggcgg agtacatgcg tatgagaagg gaattaaacg atattataga gaggataatg 25861 gatgaagaaa tgaggtttaa gctaagagac tcatggtata gttttggtag ggctcttgat 25921 aaaaaagtaa agaaatatta aaaatagtcc ggtattgccc ggactatttt attttgcaaa 25981 ttttttttca aattcttctt agagctaaat atcggtataa aattattctg cctcatgtgg 26041 aaatattatg cagcgcaagg gaaatggtat atcatattaa tcgataaaac aattcaaacg 26101 aggtgggact tatgtttacg cttttaaaga ggaaatttga tgaatcgtat aacagcaggc 26161 agattggcaa aataagaaag gatttgattg agagtctgaa aaaaatgggc gtggaggttt 26221 cgaacattca aatagatttg gaagaaaaca atgtgtcttt gaggctttca attccgcgga 26281 aaaaatacgg ttccgtccca aatgagtagg atttttcgtt aaagattata aaaagcatga 26341 aaaataaaaa ggagctacgg caagaaaata cttgattttg ccggagcccg ctttaatatt 26401 atttagcttt aatattatct acaaataaag atttttattg tgtggacaaa aacttaagcc 26461 cgttttcaat agaagccatg acactttcct ttgccggtcc tccgggaaga tttctgccgg 26521 aaacacattt tgacaggctt atttcttcat acacatcttc ttctataagc tctgagaagc 26581 ttttaaactc actcatgtca agttcctcaa tagccttgtt gttttcgatg cagtacagaa 26641 ccattttccc gataatttca tgggcgtttc tgaaaggaat acctttttta acaaggtaat 26701 ctgccatgtc ggtggcattt gtaaatccgc cttgagccgc ccggagcatg ttttcttttt 26761 ttattttcat ggtttcaatc attttggtga acaccggcag acacattttt acagtatcca 26821 cagcgtcaaa aatggcttcc ttgtcttcct gcatatcctt gttgtaagct agaggaagcg 26881 atttcataac tgacaaaagt gccataaggt cgccgtaaac ccttccggtt ttgcccctta 26941 ccagctctgc cacatccgga tttttctttt gaggcattat actgcttccg gtactgtatg 27001 catcatccaa ttcaataaaa ccaaactcat gggaggccca taaaatgatt tcttcactga 27061 accggctaag atgcatcata aggattgaaa gacaggcgga aagctcaatg acaaaatccc 27121 tgtcgcttac cgcatcaagg ctgttttcgg taatagagtc aaatcccagt tcttttgcca 27181 ccatgtatct gtcaagagga taggttgtgg aggccagggc gccggaaccc aggggcatta 27241 catttattct tttatagcaa tcgttaagcc tttcaatgtc ccgtttgaac atctgaaaat 27301 atgccatcat gtgatgggcg aaagttatgg gttgagccct ctgcaggtgt gtatatcccg 27361 gaagtatggt gtcaatattg ttttttgcta tttctataag cgtcctttcg aggttcacca 27421 gcaatttcct gatttcaaca acctcatccc taagatacat ccttatatcg agggcaacct 27481 ggtcattgcg gctccttccg gtgtgaagct tctttcccac atccccgatt ctcgatatga 27541 ggattttttc aacgttcata tgaatatctt cggcatcaat ttcaaactgt acttttcctt 27601 cttcaatgtc ttttaatatt tcccttaaag tattttgaat aagaatggag tcttcctcgg 27661 aaataatttt acattttcca agcattttgg catgggcaat gcttcctaat atatcttgtt 27721 tgtacatacg acagtcaaat cttatggatg aattaaaatc atccaccgat ttgtcggtat 27781 ttttttcaaa tctaccgccc caaagtttca tcttatcacc ttatttgcct ttattctttt 27841 ctttcataag agcctgaacc ttcatcggaa gaccaaagag atttataaat ccttcggcat 27901 ccttttgatt gtatacattg tcttctccga acgtggaaag ttcttcactg tagagggaat 27961 aatcggattt ggctcccgcg cttattatat ttcctttgta aagttttaat cttactgtac 28021 cggtaaccgt ctcctgagta acatcaacaa aggctgaaat agcctcacgc agaggagtat 28081 accactgtcc gtaataaaca agctctgcaa atctttgagc cacaagatct ttgtaatgga 28141 gagtgtcacg gtcaagacac aaaagctcaa gctctctgtg agccgcataa agaatggttc 28201 cacccggagt ttcataaacg cctctggatt tcattccgac caatctgttt tccactatgt 28261 caacgattcc tataccgttt tcaccgccga ttttgttaag aacttcaata agctccacag 28321 gtccgtattc cacaccgtta acttttttag gtataccctt ttcaaaatat atttcaacat 28381 aggtgggttt gtccggagct ttttccggcg gaaccatgag ctttaatatt ttgtcatact 28441 gcggttcgtt ccatgggtct tccaaatcca agccttcatg gctgaggtgc cagaggtttc 28501 tgtccatgct gtagttgtct tcttttgata caggaatggg gatgtttctt gcctgggcgt 28561 attcgatttc atcttctctg gatttaatgt cccatattct ccacggagca atgattttaa 28621 gatggggagc aagagctttg acggtcagct cgaaacggac ctggtcgttt ccttttcccg 28681 ttgctccgtg agcgactgct gtagcgcctt cttttaaggc aatttcaacc attctctttg 28741 ctataagagg tcttgcaaag gatgtaccca aaagatattt tccttcatat acggcacctg 28801 cttttaatgt ggggaaaata aagtctgtca caaattcttc tttcaagtct tcaatatata 28861 ttttgcttgc cccggttttt atagctttct ctcttaaggg ttcaagctct tcgccctgtc 28921 caacgtcagc tgccattgca atgacttcat agtcataatt ttctttaagc cagggaatga 28981 ttattgaagt atccagaccg ccggaatagg caaggattac tttttctttt tgactcatac 29041 aaatacctcc ttaaatatgt tagaatatat tattagtgaa ttaaattatg ctcataaatt 29101 atgcttaaat attttaaaac ctcagaaact taaaacctca aagcagtatt taaaaaaccg 29161 ttacgggcaa agttaaagct accgatataa tgagatatat tatacaataa aatgtataaa 29221 tatgcaatga aggatataat tattcacgaa tattttcaga aaggataaaa acaatgatta 29281 taatgggaat tgaccccgga tttgcaattg ccgggtatgg tatagtaaaa tatgaaggaa 29341 acaagtttac ttccgtagat tatggcgcaa ttaccactga aagctcaatg gagcttccaa 29401 aaaggctttt ggttttatac aacggtttga aggaaattat tgagaagtac agacctgagg 29461 caatagctgt agaagagctt tttttcaata aaaatataaa aacggctctt gccgtggggc 29521 atggaagagg tgttgcggtt ttggcggccg ctcaatcggg aattgatgtt tttgaataca 29581 ctcccattca ggtaaaacag tcaatagtgg gatacggaag ggcggaaaaa acacaggtac 29641 agcagatggt aaaagcaata cttaatcttc cggctatccc taagccggat gatgtggcgg 29701 acgcactggc tgtggcggta tgtcatgccc attcctataa aatgataagc tatggactgt 29761 gatataaacc cagaaaacag gaaaaaattg aaccggagga aattaaattg tttgcatata 29821 tcagaggaag acttgaatac aaaaacaatg attttttgat tgttgaatca aacggagtgg 29881 gatacaggat ttttacgtcc ctttccacca tttcgggcat tggcgagata ggacaggaag 29941 taaaggtcta cacatatctt tatgttcggg aagacgttat aagcttgtat ggatttttaa 30001 ctcaggaaga gctcaatgtg tttgaactct taatcagtgt ttccggtgtg ggaccgaagg 30061 cggcggtatc ggttttgtcg gcaatatcgc cctccaggtt cagccttgcg gttataaccg 30121 atgatgtaaa gacattgaca aaagctcagg gtataggaaa gaaaattgcc caaaggataa 30181 tacttgaact taaggacaag ataaagaaag aacagctgac agaatatgcc caaagtgaag 30241 aaggcggcaa agttttggac acggacagtt caaaaatggc ggaggcggta agcgccctta 30301 tggttttggg atattctccg gctgaagcaa ataaagcggt atcggcggtt tacagggagg 30361 atatggacat cgaaacgata attaaaaatg ctcttaaagg actggcaaga ccttaaatga 30421 gcattaagca gcggtcaaag ctaaattgtg atttgatgcg gaacctgtaa agttaacggt 30481 gaagactatt tatacagatt tggaggttgt ggcaatggaa gacaggcttg tcggttgcag 30541 gcttagtgaa gaagatgttg atgaggtaag tttgagaccc agaaagttcg gagaatatat 30601 cggtcagaca aaggtcaaag agaaccttat ggtttttatt gaggctgcaa agaagagaaa 30661 tgaagcattg gatcatgtgc ttctttatgg acctcccgga ctggggaaaa cgacccttgc 30721 cggaataata gcatccgagt tgggagttaa tttgcgtatt acttccggtc cggccataga 30781 aaagccggga gatttggctg ccatacttac caatctcggc aatttcgatg tcctttttat 30841 agatgagatt cacaggctga acaggagtgt cgaggaaata ttgtatcctg ccatggagga 30901 ttatgctttg gatataatta tcggaaaagg ccccagtgcc aggtcaatca ggcttgacct 30961 tccgaaattc accctgatag gtgccaccac cagggcaggg cttctgacat ctcccttaag 31021 ggacagattt ggagtaataa acaagctgga attgtatagt gtggaagaac ttggacagat 31081 tgtgaagaga tctgccagga ttttaaatgt cggcattgaa gatgaggcgg ccgaagagat 31141 agccaggcgc gccagaggta cgccaagggt tgccaacagg atattaaaaa gaattaggga 31201 ttttgcccag gtaaaatccg acgggtttat aacaaaagag attgccagaa cagggcttga 31261 ggctttggaa gttgatgaaa tcggtcttga cgcggtggac agaaatcttc ttatgagtat 31321 tattgagaaa tttggaggcg ggccggtggg acttgacaca ctggcggcca caataggaga 31381 agagccggat acgatagagg atgtatatga accttatctt ttacagcttg gatttataaa 31441 caagactccc cggggaagaa tggctacaaa acttgcctat gagcatttcg ggcttaaata 31501 tgaataatgt tgcttagctt aaatttctga ctgatttaga atttgtaaat aacgataaat 31561 aagcggagga gaaaaatgaa actgttgctg cacatatgct gcggaccgtg tgccgtatat 31621 cctgtaaatg tgcttaggga agaaggaatt tattttgaag ggctttttta caatcccaat 31681 attcatccct atgatgaatt tataagaaga aaggaaaatg tgaaaaaact ttcggaaatt 31741 aaaaacgttc ctgtaaaata tatggatgat ttttcgcagg aaatatggga aaaacttggt 31801 gaggacaatg aaaaacgatg caatatgtgt tatgcgttaa gaatcgacaa agttgcaggc 31861 tacgcaaaag agaacggttt tgacgctttt accacgactt tgctggtaag tccgtatcaa 31921 aagcatgagc ttattgttga actttcaaaa agagctgggg aaaagtacgg catagagttt 31981 ttttacaagg atttcaggcc cggtttcagg cagggacagc aggaagccaa agagttagga 32041 ctctacagac agaagtattg tggatgtata atatcttata gggaggcaga aaaattaaaa 32101 agcgaaagaa agagcaaata ataaaagttt tgatataaaa attggagatt tcatgcagaa 32161 ttattgattt tttttcaata ttgtgctaat gtataattgg aaagaaagtt ttagaaaatg 32221 ataactcaat tctattatgg ggttaaggga gttaataatg tatgttgtta ccatttttga 32281 gaaataatta tctaagcatt gatattggtt ttaggaatat caaagttgtt gaagtggcag 32341 ttaacaggaa caacgaagtc tacatcaaca attttggaat agctcctact ccgttaaatt 32401 gcataaaaaa cggcgttatc aaaaatgtgg atgcggtatc cagcgagatt agcaggataa 32461 tccgggagaa caagatgaag gtaaagaagt ccaagattgt tatgtccggt accagcataa 32521 tttcgagagt gtttatgatt gaaaaagtac cgggcaagag tattgatgag cttgttcagg 32581 aagcgataat gtccaacttg cctatcaacc cggatgaaca caaaattgac tacaagattt 32641 tgcaggagtt gaaagaagat aacgtcgaaa aggttaaagt ttttgtaact gcagtaagaa 32701 aaagcataat aaacagttac attgatgttc tgtttgaact tggtttaaaa cctgtttcag 32761 ttgatatacc ggcaaacagt acggcaaaat ttttcaacag agatataaag gtcagcattg 32821 acaatgttaa gtttgtaaac cccaatagaa gtcagttgaa caaagatgct tttgcagtta 32881 tagattttgg ttcggaaacc acgattataa atattctgag aaacaaaata ctggagttta 32941 acaaagtaat attaagcgga agcagcaatc tggacgaggc aatagctaaa aatatgcgca 33001 agtccataat tgaagctgaa aggcttaaga aattgtatgg catttcggtt ccgccgcacc 33061 attccaccaa cgaggagcat atgaaggttt acaggatttt aaaggaagtg gttgataagc 33121 ttttgaacca gatttacatg tgccttactt tttatgaagc tcgttgctat ggtgtaaaag 33181 tcggaaagat atttataata ggcgggggtt cactcttaaa aggtttggcc gactatatgg 33241 aacaagtgct gcaggtacct gtttatcctg tgggactttt ggatatagac ggtattgata 33301 taaacaaaaa tctaaacagc gacaagctga atttccttgt gaatgccgta ggaataacgc 33361 tgtaatttga tttcggtttt aacggttgtg tccgatactt gaaaggaagc cttacacagg 33421 cttcctttgt tattgttgca aaagtgttgt tgcggtaagt tgcgctgttt aaatttatcc 33481 aaaaaagcca tgggcttctt gttacaattt agttacaaat ggtctataaa gcctttttac 33541 gacaggaatt attttaaaca tgtcgaatat catataacgt gactgtcgat tttctggact 33601 tgcaaatatt agcaaaccta tatgataaca taaaattgat tgccaaagat aaattatttt 33661 taagaggtgt tcatatgaag aggggtcttt tcgttctgtt tgttgcaatg gttcttgtat 33721 tcaattcttt cactatgtgt gcagaagcgc tgaagcttac ttatgacggc aaagtgcatg 33781 agtatacggg aaatatttac acattgaaag tcgacggtga agttgtcaat tccgatttgc 33841 ctccaattat aattaacgga cgttctttag tccctgtcag agcgattttt gaaaagctcg 33901 gtgcaaaggt cggatgggat gcggcgagta aaaaagtgac aatatcatat gacagcaaca 33961 caatagagct caaaataaat gatgtaaatg ccctggtaaa cggaaccaaa gtagcgatgg 34021 aagttccggc aaagattata aatgacagga ctgtggttcc tgtgcgcttt gtcggagagc 34081 agctgggcat ggaagtcgga tggaatgcgg aaaaaggcga gattactttg gacagcggaa 34141 aaagcgttgt tgccagcata aatgatatca attataaaat tgacggaaac ttgcatcagg 34201 taaaaataga gctcgataaa tgcagggaat acaaaataat gagagttgcc aatcccgaca 34261 gaattgttgt ggattttccc aatacgaagc tttcaaatgc caacacaaac attagtgtgg 34321 gcagtgagct tataagttcg atacgctgcg gaaatcccga tacaaaaacc gcaagagtgg 34381 tgctcgatgt ggttggccag ccccagtaca tagtaaaaga agagggaagc aatgttgtat 34441 tgaaccttca aaagccaaat acgggtagac catccggaac tgtgggcagc aataaacttg 34501 atgttgaaca tgtcagtaaa accgaccatg acgaagtata tataaaatgc gggactgctc 34561 ctgaatacaa ttcttttact ctttccgatc ctgaaagaat tgtgattgac gtatcaggag 34621 cgtatattga gggcgaaatt aaaaatattg aaacaaaagg caacctggta aagtccgtaa 34681 gatgtgcaaa ccagagcggt aatgtggcaa gagtggtggt tgatcttcag caaaaattga 34741 accataaaat cataaaatcg ggagaatatc ttattgtata catatccaga gcacctattt 34801 cggaaaatcc tgcagtttct ttgcccagcc gcggaggcac cggcaaagat gaagggtcaa 34861 gggacaatat tctttatgtt gcctatgaac ctgacggtca aaaggacaag gttgttttaa 34921 gccttgacag ttacgagaat tacaatattg taaagaatgt tgaaaaaaat aaaattatta 34981 tcgacatacc caacgccata ggtccttctg aggcaaaaac aatcagcgtt gacagtgata 35041 tggtcagcag cgtcaaatat gtcggctttg acaagtcgta tgcacaggtg gagattgggc 35101 ttaaaagcaa aattcaatac gaagtaattg aaaaagaagg cagacttgaa ctggttcttt 35161 ccaaagctgc cgaagtttcg ccgtcgccat ctccaacacc tacgcctaca ccgactccga 35221 cacagacacc tacctctacg ccgacaccga cgcagtcgcc gactccaact ccgactccga 35281 ccccggtgca ggtggtgaag gatggttctc tttcaatagc ttataacgtt gcatccactt 35341 acagcaaagt catacttggg atacagaatt ataagaatta taatgtaaac cgtatttcag 35401 accctgatcg tattgtgatt gacataacgg gggcaaatgt tgagaaaact gcgaataccg 35461 ttgagataaa gaagggattt atagaggcaa taaggtattc gcaatatgaa gtgggagttg 35521 tcagggttgt tattgatgtc aaagacaatc cgaagcacga tgtgaaaaaa tcgggagaca 35581 aattggagat ataccttaaa gattcagttt caggtcaaaa ttataaaaat ataaagtatg 35641 tcaacaacat ggacagaata cacttcatct tgcaaggagc aaagcttacg gagggcggag 35701 ccgaccttaa gaagttttat actgaaaagt atgacctcgg cggaaaaaga tatacaataa 35761 cattcccttc aaaccttgct gatattggca gcggcataat gcagataaac gacggaatag 35821 tagattatgt caagattact caaaatcctg acacaaaaca aacaagcatg gaatttaaca 35881 caaaagaagc ctatagttat ttgataatta cccggggtga cgtgaacaat acaaccatca 35941 cactgctgaa gaaagcatcc agggacgaca agcttgtggt cattgacccc ggacacggag 36001 gtttggaaac cggtgcggtg tacggagact gctatgaaaa ggatttcaac ctcgatattg 36061 caaagagact gaacgcactt ttaaagagta aaggtgtcaa aacttatatg attcgtgagg 36121 atgacagtta tgtgggcttg tatgagagag catatattgc aaatactctc aacgccacac 36181 tgtttttaag catacacaat aatgcatata ataccaagtc tcatggaact gagacactgt 36241 attatccgac accggcagga gctaccggat ttaccagcaa gaggtttgcg cagattattc 36301 aaagccgcct tgtcagcaag ctgaagacaa aggacagggg aattgtggaa agaccgaatt 36361 tggtagttct taaagcgact aaaatgccgg cggctttggc ggaagttgcg tttatggaca 36421 atagcgaaga actgcaaaag cttaaaacgg aagaattcag gcaaaaagcg gcggaagcac 36481 tgtgtgaagc cgtaattcag gctttggcgg aagtagaata gaaataggat agtggggatg 36541 aaacaaagaa aagaaggtgg tgtaaaaaac tgccttcttt tttattatcc cttgttttaa 36601 ataaacagac tttgtgttat tataaaatat ggataaagaa tgcaaaggtt ctaaagctgt 36661 atgcaaaaac aaggtgcata tggctttgtc atcttgggtg gcataataaa caatagagga 36721 aaggttgtgt ttgaagtggc agtattggtt acaggaggag caggttatat tggaagccac 36781 acagtggcgg aacttgtaga aaagaaggaa gaggtaatag ttgtcgataa ccttgaaaaa 36841 ggccacaggg atgctgtggc aggagcgaaa cttattgtag gtgatttaag ggataaagaa 36901 tttgtgaaaa aagtattttt ggaaaacgat attgaagcgg ttatccattt tgcggcttat 36961 attgaagtag gcgaaagcgt ccaaaatccc ttaaaatatt ataacaacaa tgttatcgca 37021 actttaaacc ttcttacggc aatggaagag gcaaaagtcg acaaaattgt attttcttcc 37081 acggcggcaa cctatggtga gccggaaaac ataccgatct tggagactga cagaaccctt 37141 cccaccaatc cgtacggtga aaccaagctg gctgttgaaa aggctcttaa gtggtgtgac 37201 agagcttatg gtattaaata cattgccttg aggtatttta atgccagcgg tgcccatgaa 37261 agcggagaaa taggcgagga ccattctccc gaaagccatt tgattcccct tgttatccag 37321 gcagccctgg gtaaaaggga atccataaag atattcggaa atgattataa tactccggac 37381 ggaacatgta taagggatta catacacgtt tccgaccttg caaacgccca ctatcttgcg 37441 ttgcaaaggc tcagagaagg caaggaaagc gcggtttaca atcttggaaa cggaaaaggt 37501 ttttccgtaa aagaggttat tgatgtggta cgaaaagtca cgggaagacc gataaaagtt 37561 gaagacgctc cgagaagacc cggagacccg gcagtactgg ttgcttcatc ggaaaaaatc 37621 aaaaaggagc tgaactggca gccacgcatg gctgatctcg agacaattgt aagcactgcg 37681 tggaaatggc acttatccca tccgaacggc tataatgaca aataataagc aaaaaagata 37741 ataaaacttg ataaatagat tatattattc ccggcttctg tctataatta cagtaatact 37801 aatattttac tgtaaggagt aggtaatatg aagaagctgg gatgtcttgt tattgcttta 37861 ctggttgcat ttttgttcgg atgtcaggta ccgacggata aaacaactga aaatgaaaac 37921 ggtgtgaaca gcccggatat tgataaagaa gttatgagct tgaatgacgc aatagatgag 37981 aaagaaaatg gggaaagaaa tgaggaaggt gctgcaggtg agagcggcaa agaatcaagt 38041 aaatctccgg aggcttggaa ggaaagtgta ttaagcactg tggagccgtc ggtggaaaat 38101 ggtgaaagta aggaaaaaag caaggaaaaa acgaaaattg ctgtgaccgt gtattacagg 38161 gacagcgaca actgcctcat tcccataacg agagatattt ataaagaaga gggcattgcc 38221 aaagccgctt taagatgcat ggtagacaat gattcaaatc gcagtgcggt gcaatctctg 38281 ggactttatc ctgttttgcc ggaaggtacc gaaatattgg gaatgaacat aaaagacggt 38341 atcgcaacgg ttgactttaa tagccgtatt ttggactaca aagacaaaac agctgagaat 38401 aatatagtgg cgggtgttgt atactgtctt actgagttta gcacaattga cggcgtaaaa 38461 atattggttg aaggcatgga aaaggaaaaa ctgcaatatg gcgccgatat atccggtgtt 38521 cttgacagag acaatgtgct tataaattcg gataaggtaa accttcagga caaactgaaa 38581 aaagcggaca tttacatgtt taagtacata aaagacaaaa atgagtttat tattccgatt 38641 tcaatggaat atatcggtgt tccggaggaa gaacttccgg cgcagataat aagaatgctg 38701 gctgaaaagc ctgccaacga gagaatttat tctttgattc cgtcgggagt cgaggtgctt 38761 ggcagcagga ttgagggaaa ccttcttata ttggatttta acaaagaaat aaaaaactac 38821 gggggcacgg ccagggaaga aggtattttg aagcagatac tgtatagtat gaagcagctt 38881 aaaaatattg agaaaatacg aattcttatt gagggcaaaa aagaccatct tcccgaaggt 38941 accgacatat ccggcgagat gttgcttcct gtggaaatta acagacaaaa agacttgtaa 39001 tttgttttaa attataggaa aattaaaaat attacaggaa ttataatgac ggcagaaagg 39061 tgtgaacatg ttgagaattg atggaagagg ccagtctgat ttaagaccgg taaaaataac 39121 gcgaaactat atcaagcacg ccgagggctc ggttttgatt gagatggggg atacaaaggt 39181 aatttgtacg gccactgtgg acgacaaagt gcctcctttt aagaaaaaca ccggtgaagg 39241 atgggttacc gcggaatatt caatgctgcc gagggctact gcggcccgta atccaagaga 39301 tataagcaaa ctgaagctca gcggaagaag ccaggaaata caaaggctta taggaagagc 39361 acttcgctcg gtggtgaatt tgaacctttt gggagagagg gaaattataa tagactgtga 39421 cgttattcag gcggacggcg gcacaagaac cgcctcgatt accggcggtt ttgtcgcttt 39481 ggtggatgcc tgcaagaaac ttgtggatga cggcataatt gaaaaaatac cggtgaccga 39541 ctttttggca gcggtaagtg tcggtattgt agacggcgtg gaaatgcttg atttgtgcta 39601 catggaggat tcgaatgctg ccactgacat gaatgtcgtg atgacatcaa aaggcgaatt 39661 tattgagatt caggctaccg gtgagcaatt acctttcaaa aaagagcagt ttgacaaact 39721 tttaagtttt gcggaaaaag gtataagtca gttgattgaa atacaaaaag atgctttggg 39781 tcaggtagca agtgaggttg ggagagttac gaaagatgag aaaatttgta attgcaacga 39841 agaacaaggg caagcttaag gaaatacagg aaatattgga cggacttgat tttgaagttg 39901 tatcaatgga ggaaatgggc ataaccaagg atattgaaga gtccggaagc actttcgagg 39961 aaaatgccct tatcaaagcg agggaagttt ataaagcttg cggcgagata gtgatggccg 40021 atgattcggg cctggaagtg gactatttaa acggtgctcc cggtatttat tcttcaagat 40081 ttgcaggaga aggggcaagt gacgaggaca ggaacaacaa gcttctctcg cttttaaaag 40141 atgtgccctt cgagcaaaga aaagcaaggt ttgtgtgcgt tattgcggtg atactttccg 40201 atgaagaata ttttacggta aggggaaccg ttgaaggtta cataggcttt gaacctaaag 40261 gcgacaatgg ctttgggtat gaccctttgt tttttattcc ggaatataat atgacggcgg 40321 cacaaatgaa gccgtccaaa aagcatgaaa taagccatcg gggaaaagcc atgagaatga 40381 tgcttgaaga gcttaaaaag aggttggacc tgtaaaggga aaatcgttgg gaaaattgtt 40441 ttgtaaacag cggttcgaat ttggataaaa attttatatg aaattttaga attatggatt 40501 atatttataa taatagaaag gctgttgcaa aaagcaatag ccttttgttt gattcttgat 40561 atttacataa aatgtacggc acggaaatta aagcttgtat tttgttcagt ttattgatat 40621 aattttattg taataatgtg ttaacaataa acgttttaat aattgattgt tcgttgttga 40681 ttgcacgagt gattttagca tgccatcttc caattcattt ctgttatttt catcgctgct 40741 gttaaaataa acgattaagt tgtgtttttg taggcaatta gggttatttt atataaacct 40801 taataatata ttaatattag ggggatttgt tatgcaaaag aaattaattt gtttcctggt 40861 ttttgcattg ctgtcttctt ttttgtttgt cggcaactca tttgcggacg gaaactggaa 40921 aacttattac gagttatatc ctgatccggt tgtgacggat accagtgctg tcattagatt 40981 taagattatc aaagtaaaaa ttgacgacta tataacaatg ccgggatatg tgtacgatgt 41041 tgaatactgg aaaactgatg aaccttcaaa cgttatgcat agctacaaca tcttatgggg 41101 ggaatccagc aagcagatct cagaagggat tagtgaagta gtgtatagga ctgagctaac 41161 cggtttggag ccgaacacag agtatacata taagatttat ggacaaatgc ctattcggaa 41221 taaagaaggt actcctgaaa ctatcacatt taagaccctt cctaaaaaac ttgtttatgg 41281 tgagttgaat ggagacggaa aaataaacag ctcggatctt aacatgatga aacgttattt 41341 actccgtttg atagacggat taaatgacac tgcttgtgcg gatttgaacg gagatgggaa 41401 aataaacagt tctgactata gtattttaaa aaggtatctt cttcgtatga ttgacaaatt 41461 tcctgtagaa aaggaagaaa aaaatgaagg tgtaagtgaa aactttatta gaggaaacag 41521 caattttgca tttaacattt tcaaagaaat taataaagat gaacagggca aaaatgtgtt 41581 catttctcct tttggcattt caactgcact ttccatggta tatcaggggg caaaatccga 41641 taccagggaa gaaatggcga aggttttggg ctatgaagga cttgatattg aagaggttaa 41701 caaaagctac aagtatttat tgcaatattt taatggtctt gataatgata caaaaattaa 41761 aagcagcaat tcaatttgga tgaattcttt acacggcaat gctattaaag aagatttcat 41821 atccacaaac aaggatgtgt ttgatgcgtt ggctgagacc cgcgactttt ctgataaagg 41881 tgttgtggat gagataaatg attggatcag caaggctaca gaaggtcaaa tagacaagat 41941 gctcagcgaa attgatatgg atatgctggc gtatattata tctgcattgt attttaaagg 42001 tacatggacg gaagagtttg atattgagaa aacggttagt gtgccttttg catctgagga 42061 cggcggcgct gaccatgtta tgatgatgag aaaggaactc tgcactatag aattcggtga 42121 aggtgatgga tacaaggctg taagattgcc atatggtgat ggtgaaatgg ccatgtattg 42181 tattcttccc gatgaagata catcgataaa tgattttatt cagaagttgg atttgtccat 42241 gtgggagaaa attaaaaaca gtataactaa aagagaaaac ggaacgattt atttacctcg 42301 ctttaaaatg gagtatgcca agggcgaaag cggcagtata atggaaagtt tgaaggcttt 42361 aggtatgaaa aaggcgtttg aggaagacgc tgacttgtcc ggtatgactg aagccgacgc 42421 atttattagt gatgttttgc ataaggcagt agtggaagta aatgaaaaag gaacggaagc 42481 ttccggagtg gttgtaatac ctatagctcc gacgagtata gcacccggac ccaagtttat 42541 tgcaaacaga ccgtttgcat tcgtaattgc ggatgaaaaa tatgacacaa tactctttat 42601 gggtaaatta tgtgacggcg ggttgattaa ttaatagttg gaagttgtat gcaatataaa 42661 atgggctgtt tcaaaataga tttttgaaat agcccattgt tgttgttctg aaaatacaaa 42721 aagcaggctt ttaaacctgc ttttttgctt gcatacttaa tatttacata aaatgaactg 42781 gatgagaatt aaagattgaa ttttgttcag tttattgata taattttaat gtaataatat 42841 gtagcaatgt gtaacaataa acgttttaac aattaattgt tccagtgtta cctgtgcgtg 42901 ggattttagc atgccatttg ccaattcatt tctgttattt tcaccgctgc cgttaaaata 42961 aacaattgag ttttttccac aggcaattaa gggctatgtt atataagcct taaattatta 43021 atattaaata ttagggggga atctgttatg cgaaaaaaat taatttgctt cctggttttg 43081 cattgctgtc ttcttttttg cttgtcggca actcatttgc cgcaaattgg tacacttatt 43141 acgagttata tcctgatccg gttgtgacgg ataccagtgc tgtcattaga tttaagctta 43201 ccacggaaaa aattgacgat tatataacaa tgccgggata tatttatgag tttaggtatt 43261 ggaaggttga tgaaccttca aaagtcaaga gtgtaagtat aggattgtat gttaatgaag 43321 ttcaaacagt agagctcact gatttggagc cgaacacaga gtatgaatgt aaggtttggg 43381 gacaaattta tacttcgaat aaagaaggta ctcctaaaac tatcacattt aagacccttc 43441 ctaaaaaagg tgacctgaac ggagacgcaa aaataaacag cacagacctt aacatgatga 43501 aacgttatct gcttcaaatg atagatagat ttggtgtaga tgacgagtct tgtgcagatt 43561 tgaatggcga tggaaaaata accagctcag actataactt gttaaaaaga tatattcttc 43621 atttgataga caaatttcca ataggaaatg atgaaacaga tgaaggtata aatgatggct 43681 ttaatgatga aacagatgaa gatataaatg atagctttat tgaagcaaac agcaaatttg 43741 catttgatat tttcaaacag ataagtaaag acgagcaggg taaaaatgtg ttcatttcac 43801 ctttcggaat ttcaatggcg ttgtctatgg tttatcaggg agcggaatct gataccaggg 43861 aagaaatggc aaaggttttg ggctatgaag gacttgatat tgaagaggtt aacaagagtt 43921 ataagttatt attgaaatat ttcaatgaac ttattgggaa tgttaagctt aaaaacagca 43981 attcaatttg gaaaaattct ttaaagggcg atgttattaa agaagatttt atatccgtta 44041 ataaggatgt ttttaatgca ttggttgaga caagggattt ttccgatgaa agtgttgtag 44101 ataaaataaa caactggatt tctgatgcca cagaagggaa agtaaagaaa gcgctcaatg 44161 ctgttaatcc ggatgaatta ttatacatta tatctgcatt atattttaat ggagcgtgga 44221 aagaagagtt tgagtttgat attaacgaca caaccatgag tacttttaaa tccgaagacg 44281 gaagcactga ctatgttatg atgatgagaa aaagctataa taattgggtg ggagtgatgg 44341 aatttggtaa gggtgatgga tacagcgcca tcagattgcc ctatggtaat ggtgaaatgg 44401 ctatgtactg tattcttcct gacgaagata tatcaataaa tgattttatt cagaatctgg 44461 atgtatctct gtggaatgaa attaaaaaca gcataaggaa aacactacag ggattgattt 44521 gtttacctcg ttttaaaatt gaatatttca aggatggaaa cggcagcata aaggaaagct 44581 tgaaagcttt gggtttggag aaggtattca gcctggctga agctgacttg accggtatgt 44641 ctgaaactaa tgcttatgtt tctgatgttt tgcataaggc ggtagtggaa gtaaatgaaa 44701 agggaacaga ggcatcctcc tcagtagttg taataccggt tccgggtttt ggaacgagat 44761 cggagtttat tgcagacagg ccatttgtat tcataattgc ggatgaaaaa tatgatacca 44821 tactctttat gggtaaatta gcaaaaggtg agttgattaa ttaatatttg atatcaggat 44881 ttctataata aagaacaaag aatccccact ttgttttccc tctacgtggg gatttttctt 44941 tgaattttaa ctaaatagcg aaaaaaattt ttaaattttt ataaaatagt attgacaaat 45001 aaaaaagttg tttgtataat gaatgagtca gttggaggtt ttcagattat gttatacgaa 45061 ctgcgggtgt agttcaatgg tagaacatca gccttccaag ctgattgcga gggttcgatt 45121 cccttcaccc gctccaaaaa tcttctatat ctgcccgtag ctcagctgga tagagcaacg 45181 gacttctaat ccgtcggtcg gacgttcgaa tcgtctcggg caggccaaga aaccctagag 45241 gcgagagcct tctagggttt tttcttgaaa aagattagag aatgaaaaat tgacttaaaa 45301 ttgaataaaa ggtgatggag ttcacctgaa atgcgtaatg ctgatgactc ctacaggaat 45361 aataatactg tttctgtagg agttttttgt tacttgggaa gggagtagtg ttttatggct 45421 gcgagtttag caattatttt attattggga ttaccggcaa aacgaatatt tgaaaaatta 45481 agattacctg gtttgttggg aatgttgata ttaggcattc ttataggacc tcatgttctt 45541 aatctgcttc aaacggatat gcttcaaata tcttctgatt taagaagtat tgcattaata 45601 attattttat taagagcagg actcggactt aacaaggatg aattgaaaag tattggaatc 45661 cctgcattaa agatgagctg tattcctgga ttatttgaag gtttatttat tgcactggct 45721 tctgtatatt ttcttgattt tacatttgtt cagggaggaa tgttagggtt tattattgct 45781 gctgtttctc ctgctgttgt agttcctttt atgcttaagt taaatgaaaa taaaattggt 45841 acaaaaaaag gagtaccaac tttgatattg gcaggtgcat ctattgatga tgtctttgcc 45901 attacggttt ttagcgcctt tttgggttta tattatggtt ctgaaataaa tataggcatt 45961 caattattaa atattccaat ctcgatttta ttgggaattt tgtctggaat tcttgtaggg 46021 tttttactga taaatatttt taaaaaatat aatatcccgg atacaaaaaa ggtgttatta 46081 atacttggat tttcaatatt actcaatcag ttggaaagtg tattgaaaac taaattacgg 46141 atagcatccc tgcttggagt tatggctatt ggctttatat tgactgaata tcttcctgat 46201 acaggcaaaa aactttctga taaatttaat aaggtgtggg tatttgcaga aatattgctg 46261 tttgtattag taggagcaga ggtaaatgta aatgtggcat taaaagcagg tggaatagga 46321 attatattga tattgacagg tttaattggg agaagcgtag gtgttgctat ttctttacta 46381 ggcacagatt ttaattggaa agaaagggtg ttttgtatta ttgcttatat cccaaaggca 46441 acagtgcagg ctgcaatggg tgcagtgccg ctgtcattgg gagtggaatc aggagacata 46501 atcttggcga ttgcagtatt agccatatta attactgcac cgttaggagc aatcgggatt 46561 cattattcgg cagaaaagtt actaatagag aaacaatagt gtaagtccca aaaaaaaaac 46621 aatataaaaa attacgaaaa tgtagtacaa tattaacatg aaataagaag gaggataata 46681 aaagcaatga gtaaaaaggg aatatcgtgt gcattaattt cattgatttt ggtaatattt 46741 ctttcagcaa cggtgtttgc agaggagaca attacagcaa aattaaaaag ctatacagct 46801 tatgagtatc cttatcttat gctggaacat gttatgggac cggaaagaac agtttactat 46861 gcaatatgtt ataattctga aggacaagtg gaatatggcg aaataattag agaaatagat 46921 gatttcgtgt tatcaagagt atatctcgac ggtacaagtg aagattttga gccaccgcaa 46981 ttaacgatac agcaaatccg ggagtttgca gaaaaatatc ctaaatatga atatgatatt 47041 tgcgattggc ctttaagtta catactgtaa tgaatagaac ttttagagag tacaattaat 47101 aatctaattt tgattttaag ctatctatat agataggctt ttttgcccaa aatacaattt 47161 gtatgttgtt atttattata aaacacgtta cattgcagtt aaaaaattgt attctattga 47221 tagaaagtac aaattaggag actaaaatta gttaactgtt taatcaataa aataacatga 47281 ggaagtgaaa tggtgaataa tgacggtatt ttgatagaga ggattttaaa aggcgacaat 47341 acaggattta atagaaacaa agatttttta ccctgggtct ttaaaatcgc tttcaattta 47401 tatagaaact tctacaaaaa aataaaaaga agttaagaga attgcgtttt gaagatttgc 47461 aagagcaact tcatagaagc tctgaggata gcttgttgtt actggaaaag gctggaagcc 47521 taaaagaaat tctgctgttt gtggatgaac taaaaaaaga tcaaaaggag atttttattt 47581 taaaatacgg caaagggttt acgtttaaaa caattgctga aattaccgga atatctgaaa 47641 ttgaaaagag caatgcggaa ttgaagaaaa gcggatggat tgaaataccg gagataaaat 47701 ccaaagaaat agtatacgta aataaaaagg ggagaactat tacccatatg agaaataaaa 47761 tacgacggta ttactatgca agttgatttt ataagaaatg accactctgc aatggcagag 47821 tggttataat atacagagtg gatatatata gaaggtctac tggataccta agcttataaa 47881 tatagctaaa aggcgtgcaa tctattttta acgatagact acacgccttt gtgaggctta 47941 atattaataa acactgtaga gaagctctcc gtaagtgggg aacggccagt attttttgcc 48001 gatttttgtc tcaagattgt caattacgct tcttaattcc tgcatattaa tgaaaactac 48061 ttctctataa tattttgccg tatttaaaag accatcctga tttttagcct cgagaatgga 48121 gttatccaat ttctcaacgt ttttataaag acaagcggct aaatcagata tagtattaat 48181 caaactttcc tcgagtttgc agttgaattc actgcttatg gcctttttgt ttttgacaac 48241 ctccgtcaaa tctttaaggt actcaacaac cgcaggtata atacctcttt tcgtcatgtc 48301 gagtatcgtg agggcttcaa tgtgcagtac tttgatatat tcttcaagca ttatattata 48361 tcttgaatga atctcagact ctgaaaagat gttgtgtttt gtaaacagtt ttatattttt 48421 ttcagatatt aaatacggcg cggcttcaac aactgattta agatttaaaa gccctctttt 48481 ttcagattct tttacccact cctcagagta gttgttgccg ttaaatataa ttctcctgtg 48541 cttcttaatc gtttctttaa tcaatgcgtt caattctgct ctgaagtcac cggcgttttc 48601 aagtctgtcg gcaaactggc acagagcttc ggcaacaata gtattcagga cagtgtttgc 48661 atcggatata gatgcgctgg aacccaacat tctgaactca aatttattgc cggtaaaggc 48721 aaagggggaa gttctgtttc tgtcagtgtt gtccttgggg aagtgaggaa gtacgcttgc 48781 accgatttcc atctgaactt tttctttttt attataacct gtaccgttct caatggcttc 48841 gagaatggct gtaagctctt ctccaaggaa tacggaaatt attgcaggag gtgcttcgtt 48901 tgctccaagt ctgtggtcgt ttccggcact tgcaatggat attctgagca agtcctgata 48961 ttcatccact gcttttatga cagcacacaa aaacactaag aactgtgcat tgtcataagg 49021 agtttcaccg ggttccaaaa gatttatgcc ggtatctgtc gagatagacc agttgttgtg 49081 tttaccgctg ccgttgactc ctgcaaaagg cttttcgtgc agcaggcaaa caaggtcatg 49141 tttgtttgcg atggttttca taagttccat aatcaattgg ttgtggtcag cggcaatatt 49201 aaccgttgta aatatcggag ccacttcatg ctgggcggga gcaacttcat tgtgttttgt 49261 ttttgccaaa acaccaagct tccagagttc ttcgtccagc tctttcataa aggcggaaac 49321 tcttggcttt attgatgcaa agtagtggtc ttccaactcc tggccttttg gaggccttgc 49381 accgaacagt gttcttccgc agtatatcaa atccggacgt ttttggtata attccttgtc 49441 tatcaggaaa aattcctgct cgggacctac agttgcagca acccttttta cattatcatt 49501 tccgaaaatc tttaaaattc tcttggcttg tttgtctatt gcttccatgg aacgaagaag 49561 cggggtcttt ttgtcaagtg cttctccgct gtatgagcag aatgctgtcg gaatgcacag 49621 ggtgttgtct ttaataaatg cataggaagt agggtcccac gcagtataac ctctggcttc 49681 aaaggtagat ctgattcctc cgctgggaaa gcttgaagca tcaggctctc cgcggacgag 49741 ttcttttcct gagaattcca tgattacgtt tccgtcaccg accggagata taaagctgtc 49801 atgcttttct gctgttactc cggtaagggg ctggaaccaa tgggtaaaat gggttgctcc 49861 tttttctatg gcccattctt tcatggctgt tgcaacgacg ttggcaacat ccagatttaa 49921 gtgtttctgc tcgtccattg ttctttttag agctttatat acatctttag gtagtctctg 49981 tttcatgact ttatcgttaa aaaccatact tccgaataca ttggggatat cttgcatttt 50041 aattcctcct taaaattata ataaactgac tcctttttcc cggcatacgg cgattgtttc 50101 atagtcccaa acgaatactt tcgcttctcc tctatgagct ttagcaggaa aaagcatgca 50161 aattctggac ttgccgattc ctcttactgt attaaaggaa actcaccgtt tttattttgt 50221 catccctttc aaaaaaaatt aagacgccaa tgagcttttt aagcccatag cgcctttgct 50281 ttatatgtgt agtataacat caaaataatt aaatgtaaat acttttttta aaaaattgca 50341 agattatttt attaaagttg caaaaaaatg aagagaaaca ttttaaaaga tggtatttta 50401 tgcggcctgt ctaatgtgac atgaaattta aaataataaa tccttcaatt taatattgac 50461 agaattgttt ttttaacgta ttataatagt acagtgaaca aaggcgttca ccaaacagca 50521 aaagtatgta cgtgcttttg ccgttggtga gcgctttttt acattataga taataaaaaa 50581 tgtattttgc agaatacatg agatttattt attacagagg tgggtgttat gttgaaagaa 50641 ggtcaaataa ggataccgtc gggttgcgcc atatcgggta tattttcaaa gtccggaaaa 50701 aggataagcg gagaggcaat catcaaatcc attgcaacaa tgcgtgatcg ctcaaacggc 50761 ttgggcggag gatttgcagg ttatggaatc tatcctgaat acaaagattt ctatgctttc 50821 catatatttt atgacggtga tgtggctaaa gaagagtgtg aaaagttttt ggaacgtcat 50881 ttcgatatca taaatctttc caaaatacca acgaaaaaga ccaagggaat aacagatgct 50941 ccattgattt ggagatattt tgtcactcct ttaccgacaa aactcgatga aagccagctt 51001 gacgaaagag agtatacagc aagatgtgta atgaagataa acaaaaagat agacggagcg 51061 tatgtgtttt ccagcggcaa aaacatgggc gtattcaagg cggtaggttt tccggaggat 51121 gtcggagagt tttacaagct ttatgattac gcaggttatt gctggaccgc tcacggaaga 51181 tatccaacca acactcccgg atggtggggc ggtgcccatc cttttgcact tttggattat 51241 tcggtggttc acaacggtga aatatcttct tatgatgcca acagaagaac tattgaaatg 51301 tatggttaca agtgcacgct gctgacagat acggaagtaa ttacttatat tatcgactat 51361 ttaaaccgca aagtaggttt aactcttgaa gagatagcag gagttgttgc agcacctttc 51421 tggcaggtta ttgacaacat gcccgaagaa caaaaggaaa aatacactta tcttagaaac 51481 gttttttcat caatgctgat aacggggcct ttttccatcc tggcgggttt tgagggagga 51541 attatggctc ttaatgacag gttgaagctt cgctccatgg ttgtcggaga aaaagacgac 51601 atgttttatg cggccagcga agaatgtgca attcgcgttt tggaagaaaa tttggacagg 51661 gtatgggctc cgaaaggcgg agaaccggtt atcgctacat tgaatagagg tgttttataa 51721 tgggaatcaa ttttttgtat ccggaatatg aagttgtaag aaatatggac agatgcatta 51781 actgcagggt ttgcgaaaga cagtgcgcca atgaggttca cagctacgac caggagaaaa 51841 aaataatgtg cagtgatgat tccaaatgcg tcaactgcca tagatgtgtg gctctttgtc 51901 ctacaagggc tctcaagata gtaaaaacgg atcatacgtt taaagaaaat gctaactgga 51961 gaggttcaat aattaatgaa atatacaagc aggctgaaag cggcgctgta cttttgtcca 52021 gcatgggaaa tcccaatgag tatcctgtgt attttgacaa aattctgtta aatgcctccc 52081 aggttacaaa tccttctatc gacccgttga gagagcctat ggaaacaaaa gtgtttttgg 52141 gcagcaaacc gaggagtata caaagagatg aaaaaggaaa gcttgttaac aatttgtcct 52201 gcggtattga actttccgta cccattatgt tctcggccat gagttatggc tccatcagct 52261 acaatgccca tgaatctttg gcaagagcgg caaaagaagc gggaatcctg tacaacacgg 52321 gagaaggtgg acttcacaga gacttatatc aatacggtag caatactatt gtacaagtgg 52381 cttcaggaag atttggagtg cataaagact atcttgaagc gggagctgct atagaaataa 52441 aaatgggtca gggtgcaaag cccggaatag gaggacatct tccgggaaca aagatagtag 52501 gggacatatc cagaaccaga atggttcctg aaggttcgga cgccatttct ccggccccgc 52561 accatgatat ttattcgatt gaggacttaa ggcagctggt ttattcgctc aaggaagcaa 52621 caaattacac aaaacccgtt atagtcaaaa tagcggccgt ccacaatgtg gcagccattg 52681 ccagcggaat tgcaagaagc ggagcggaca ttatcgccat cgacggattc cgcggaggta 52741 ccggagctgc tcccacaaga atcagagaca atgtgggaat tcctattgaa cttgctctgg 52801 caagtgttga ccaaagactt agagaagaag gtataagaga caatgtatcc attgttgtgg 52861 gcggaagtat cagaaacagc agtgatgttg taaaagcagt tgcattggga gccgactgtg 52921 tttatatcgg aacggctgcg ttgattgctt tagggtgcca tctttgcaga agctgtcata 52981 caggaaagtg caactggggt attgcaaccc aggagcctga gttggtaaag cgccttaacc 53041 ccgacatggg ctataagaga ctggttaatc ttgtgaatgc ctggaagcat gaaataaaag 53101 aaatgatggg cggaatggga attaattcta tagaaagcct tagaggaaac aggctgatgc 53161 taagaggagt aggacttaat gaaaaagagc ttcaaatatt aggaattaaa catgcggggg 53221 aataggaggt gctttgggtt gaagagggtg tatgtaaacg agaaatggtg cctggcgtgt 53281 catttatgtg aatattactg tgcttttgcc aattccaatg aaaaggacat ggtcaaagct 53341 ttaaaagaca tagtaataaa tccaagaatc cgggtggaac aaaaggataa tataagcttt 53401 gccgtgtcct gcaggcattg tgaagagcct ttgtgtgtga agggctgcat tacaggggcg 53461 ctttcagtta aagacggagt gatatccgtt gaccaaaaca aatgtgtcgg atgctttacc 53521 tgtattttat gctgtcctta cggggcagta agcccgggtg aaaaatcagt cattcaaaaa 53581 tgcgagctgt gcaccaataa catacatgga actccccagt gcgtgaaagg ttgtccgaac 53641 aacgccattg tttttgaaga gaggtgaaaa aatgaaatat gttataatag gaaattccat 53701 tgccgccgtg ggagctgtgg aaggaataag aaaaattgat actgaaggcg aaataacgat 53761 aattggcaaa gagccttacc atgtatattc aagacctctt atatcgtatt tgctgtatgg 53821 caaaaccgat gaggaaagaa tgaaataccg cggtagtagc ttttatgaca ctatgaactg 53881 caaggtaatt ttgggaaggg aagccgtaaa gataaatgat gccaaaaaag aagttgtact 53941 cgataacggg gaagtcataa attacgacaa attgcttgtg gccaccggtt cgcttccttt 54001 tgttccacct atgaaaggtt tggaaggggt tgaaaaacga ttttcattct tgtctttgga 54061 tgatgccaaa aaacttgaaa gcgcaatttc tccatcaagc aaagttttga taatcggggc 54121 ggggcttatc ggattaaaat gtgccgaggg tatttcaaag aaagtggaaa gcattacggt 54181 agtggatttg gccgacagaa ttctgtcaag catattggac aaagacggag ccgaaatagt 54241 caaatcccac atagaaaaag aaaatataaa atttgtttta aatgcaaaag ttgaggaatt 54301 tataaatagt aatgaggctt tactcgatag cggagaaaaa gttgaatttg atgttttggt 54361 agttgccgtt ggtgtcatac ctaatacagg tttgataaaa gatataaacg gcaaggtaaa 54421 tcggggtatt gttgtggatg agttctgtca gacttccata ccggatatat atgcagcagg 54481 agactgctgt gagtcctttg atataacttc agagcaaaac agggttcttg cattgctgcc 54541 gaatgcttat atgcagggag aatgtgcggg catcaacatg gcggggggta aaaaagaatt 54601 cggaaaggca attcccatga atgcaatatc cttctttggc cttcatatta taacggcggg 54661 aagttacgtc ggggaagttt tcagcaaaat caacggggac aattataaaa aattgtttgt 54721 aaaggacgga cttttaaaag gctatattat gatcggagat gtggataagg caggaattta 54781 tacaagtttg ataagagaaa aaacgcccct ttccgagatt gattttgaat taattttcga 54841 aagacccggt ttgatggctt ttacaaggaa agagcgccag agaatgcttg gaggtgttgt 54901 tagatgatta ttaatgctca aaacttatat tataaagaat taaatcaaaa aataagagaa 54961 gcatccgata aagatattgt catagaaaat tgtctgggac aaagatatat tggagacgga 55021 cagggcaata aaaacattac gatatacggc acaccgggaa atgaccttgg ggcgtatctg 55081 gacggatgca ctataagggt aatgggaaat gcccaggatg ccacgggaga tacaatgaat 55141 gacggaacaa tttatattca cggaaacagt ggagatgtct gcggatatgc aatgagaggc 55201 ggaaaaatat ttataaggga caatgcggga tacagaacgg gtattcatat gaagcaatat 55261 aaagaaaaaa agcccgtcat agtcatcggc ggcactgcgg gaagttttct tggagagtat 55321 cttgcaggcg gaataataat agtattggga ttaaacagcg aagacaccgt tcctgtggga 55381 gacttttgcg gaacaggcat gcatggtggt aaaatatatt taaggtgcag caggcttcca 55441 caggatttgc ccaaacaggt tatcgcaagg gaagcaaatg aggaggatat ggaggaaata 55501 aaggggtata tagaggaatt ctgccgggag tttggcaaag acaaagaaca aattttaaac 55561 tccaaattct tctgtctggt tcccaatacg aaaaacccct acaagcagct gtacacgcat 55621 aattagccga gaatatggcc aaaggaggtt ttttgaggat gagttataat ataaaaataa 55681 aagaggtgct ggagtttgtc gaagaaaatg acgtgaaatt tatccgactc gccttttgtg 55741 atattctggg gattccaaag aatatttcca tcatgcccca ggaacttgaa agagcgtttg 55801 aacaaggtat atcctttgat gcgtcttcaa ttttgggatt tatgaatgtt gaaaaatccg 55861 atttgttttt acatcctgac ccatcgactt taagcatttt gccctggaga ccccagcagg 55921 gaagggtaat acgttttttc tgcgacataa agcatccgga tggaagtgcg tttgagggag 55981 attcaagaaa tattcttaaa aaagcggtgg aacgggcgga aaaaatgggg tatgcgtgca 56041 gaataggttc ggagtgcgaa ttttatttgt ttgaaaccga tgaaaaagga agacccacat 56101 atattcccca tgatgagggg ggatatttgg atatggcgcc ccttgacaaa ggggagaacg 56161 taagaaggga gatttgcctg tcgcttgaac aaatgggaat tcagccggaa agttcccatc 56221 atgaacaggg gcccgggcaa catgaaatag actttaaata cagtgacgct cttacagctg 56281 cagatgattt gatgactttc aagacggtgg tcaaggctgt tgcatcaaga aacggacttt 56341 ttgcctcctt tatgccgaaa cccattttga ctgaaagcgg cagcggactt catattaata 56401 tatctctttc aaaggacgga tttaatattt tcaaagagag gaattatgat tcttcggccg 56461 ctaaaagctt tattgccggg gttattgata aaatattgga tattaccgca tttgcaaatc 56521 cgataacgaa ttcttatgcc cggcttggaa gtttcagggc gccgaaatac gtatcctggt 56581 ctcatcaaaa tcgttcccag cttataagaa tccctgctga aacaggggaa tacagcagaa 56641 tggaacttcg ttctccggat ccggcctgca atccttacat tactttcgct cttattttgc 56701 atgcgggact tgacgggata gagagaaaat tggagcttcc cgggccgatt aatcagaatt 56761 tgtacaatgc cggcgctgat gagttgcaaa atatcaaagc tcttccgcag aatttgaaag 56821 aggctttgga tgttgcatca aaaagtagtt ttgtaagaaa cattttaggc gaggaaatgt 56881 taagcaagta tttggagata aagctaaaag agtggaacat gtattttgaa agtgaagaca 56941 gggaaagcgt ggaaaaacag atgtatttta aaattattta agattttcta agataagtcg 57001 gtggttttat ggacagtatt ttgattgtat ccagttcctt aaaagtaagt tctaccttgg 57061 aggagctgct taagtttaat tcttcttaca acgaaatcgt tatggctaga aatgccggcg 57121 aagccaaaag aatattgctt gacagagatt ttgacttatg cataatcaat acaccgctta 57181 cagacgagtt cggaaccaat ctggctataa atattgcaaa cagggaaacg tcacaggtta 57241 tgctgattgt caaaagcgaa ctggaagatg aaatatcgga caaagttgaa gattacggga 57301 tatttgtcgt agcaaagccc gttaatcgtc agcttttttg gagcgcttta aaactcatct 57361 ctgcctccca taatagaatg aaaggactta aaaagcaaaa tgagcagctt cagaaaaaga 57421 tagaagatat taagtttgtc gacagagcaa aatgtgtttt gattgagtat ttaaaaatgt 57481 cggaagccga ggcccacaga tttatagaaa aacaggcgat ggatttgagg gttaccaaga 57541 gagaaatagc gtcaagaatc ttaaaaacct atgaaaaata aatttgaaaa aataagtgaa 57601 atttttttaa aattattaaa aaatagatga ataataaatt gaaaaatggt caataactat 57661 taatgacctc acaatacatt taacccccta atagatgccc tggcgtaatg ccggggtttt 57721 aatatgttct gaaaaatttg ttataaaaca ataaaatttg atataatata tatgtaatcc 57781 tcttgttaac atatttaaag tctccgtaat tcttggcaat tatggaatcc caatatttga 57841 taacaatggg ggaaatgaat atgccgaaca acccgtatac gtatgttttt cttctgtttg 57901 caataataaa tcttgtcggt tttgttataa ccggaattga caaatacaaa gcgtcaagaa 57961 gcctgtggag gatacatgaa aggacatttt tctggcttgt tttaatgggc ggcgcaccgg 58021 gcgtatattt agggttgctt gttttcaggc acaagacaag gcgcatgagt tttatgatag 58081 gaattccttt gatttttgca tttcaaattt tgggaatcat tcttctttat gtgttgagcg 58141 agacatgaat tgagtttgtc caacccgatt ttgttgtatt gccggtgtct gttcttgatt 58201 ttttgcaaac gttcagttct gtttttggta atttgcaaat tgtcggttca atgtgtttcc 58261 tgccgaattt tttaggtgtt ttcattaatc ttccctcggt ggtataatat atgaagtaag 58321 aatttttgga gggataccta tcatattttt cgatgatgtt gcagggaaga ttattaaagc 58381 accaatagaa aagtccaaac tgatacttaa aggtcccacc ggaagcggga agtcaacttt 58441 gcttttggaa agatacaagt atatggttga cactctcaag gtacccagcg aaaaaatact 58501 gatacttctt ttaaacagga cccagtcttt ggagtggagg accaagacgt ttttggaggg 58561 ttccggcgca attctcagga cttcatattt tgggtttatt caggaagaaa taaggaccta 58621 ttatcccctt attgtaaaaa actgcagtga gattgtaaat aaaaacgtaa agcctgtttt 58681 tttgactttt gaggcttccc agtttcttgt gtccattgtt ttggactggc gcaggcagaa 58741 aaaaggagcc tttgcgggag ttacctcttt ttccgacagg cttgcaatcg atatgacatc 58801 gaaccttgtc aaggccgcta tctcagacat tccctacgac gagataggaa agcggcttta 58861 taatgctttg gagaaaaaag aggaaatcag aaaacgggtg tacgatgagg cggatgagat 58921 aatcagggac tacagaaaaa agtgcatgga gcttggaata tttgatttcg gcatggctgt 58981 ggaactgtac aacaagtgcc tccttcccga tgaaacatac cagaatcagt tgtttagaag 59041 gattgaacac ttaattgtag acaatatcga ggagtgcgtg ccctcagaag ttgattttat 59101 caatttcctg ctgccgaagt taaagacctg tcttttgggg tataatcatg aagggggata 59161 tggacaggct ttcggaagca atcatgaata tgtgaagcag cagttgattg acaaaatgga 59221 gatagtggag cttaataaat cttacacctg caaggatttt atgtatgaat tttcggacat 59281 gctttttgat tttatagaaa actctgcccc gtgcaaattc aaagcacggc ctgaaataga 59341 gagggttccg ccgctggagc ttagaagcga catgctggaa aaagcagggg acagaatcat 59401 tgagcttatt gaggatgaag ggtacaatcc ttcggacatt gtggtgatat ccaattatgc 59461 tgaccctgtc acagagtttg ttataggaag aattcttgaa agacacggat atgagataaa 59521 aaatttggca agaatgaaca agataataga caatcccttt tcccaggcac tgataacctt 59581 ggcccagttg tgccatccaa attacggctc ggtgccgaca agggatgatg tcagggcact 59641 tataaggatg gtgctgaaaa tagatccggt aagaagctcc atccttgcgg gggagattct 59701 tgcccaaaag ccctttgccc agtttcccga tatagagttt ccgggactgg tggagagggt 59761 cgggtactac aacattgaaa agtacgagta cataagaaac tggataaaag aatataggga 59821 gagggaaaaa cccctccaaa tacatgagtt tttccaaaag gtttttttag agatactctt 59881 gtctaatgaa gtttccgaaa aggatgttat tgaagccaaa aagcttattg acagtgcaga 59941 atcttttgtt aacgtggttt caaggtttaa caggaatgcc agcaaagatt ttcttgatgt 60001 tgccaagaaa gggataaagt cggcggagag catatttgag ctggaagaaa aacttaacgg 60061 caattttgtg ctgatgtcca ccccggtggc atacctgtca agcccgctaa aaagtaaagt 60121 aatgatactt ttgagtatta gcagcaacag ctggactcca agaagcatca aggagataac 60181 caatatccat gttttgacaa aaacgtggaa tgagaatgat atttataccg aggaaatgga 60241 agagaaaaat cagaaacatt acctggcggt tcttataagg tcgttgctca aaagatgtga 60301 agacaagctt ataacctttg aatccatgct taatgccaac ggttatgaaa ataacggtat 60361 tctggcggaa tattttgacg agatactgac acagtaaaat tatttgggag gcatgtttcg 60421 tggggcttag aaaagggcag aaagagctcg tggaaagata cagaggtgga aaatgcgcca 60481 ttgcggcaat acccggagga ggaaaaaccc attgtttgtc tttgtgggcg gtggagatga 60541 taacccatgg ataccacaaa ccgggtaaaa ttctaattgt tacatatatg aacagtgctg 60601 taaacaactt taagcagcgt atctccgcag agctgcaaaa aagaggaatc aacggaagca 60661 aggattactt tgtctccaca attcacggcc tgtgcctcca aattatcaag gaaaagcccg 60721 accttattat tgcaaacgag gaatttgaag taattgatga ggtgtccaag atacacctca 60781 tttccagtgc gattgatgag tggaagagat ataacgaaag agaatttcag ctgtatcttg 60841 atatggaaaa tttaagtgtg agcaagatgg gggacgtgta caaaagctgg catgaaaagc 60901 tttgcaggat aatgctttcg gcaataagcg attttaaggt aaaaggaatc actccttcgg 60961 aggcaaaaga gagatgtaaa agtctgggac gggattctat tctcgcatgg gcttccgaca 61021 tatatgagat atacgacagg aggcttaaaa tcggaggtta tctggatttt gacgacatgc 61081 tttacaatgc aaaaaaaatg ctggaaaccg atgagcacct tcttgagaaa taccgaaaga 61141 aatacacctt tgtgtgtgaa gacgaggccc aggattcaaa ctatattcaa aatgaaatac 61201 tgacactgat tgccaatgga aacctgctga gagtggggga cagcaaccag gcgatttgcg 61261 ggagcttcag cagcagcgat tttacccttt ttaaaaactt ttgcgaagct ccggacacaa 61321 cagtttacag tataactcag tccagcagaa acaccaggga aattattgac ctggcaaatt 61381 tctttgtaaa gtatgtaagg gaaagccatc cggtgcatga gtgccgtgac agcctgcttc 61441 cccagtatat cgagcctgtg cctgaggatg acccaaggcc caatccggtc atagatgaat 61501 acggtataaa agccgctgtg tttgaatcgt gggaggatga ggcaaggggt gttgtgaccc 61561 agacaataca catgataaaa aatcatcctg acaagactat tgccatactg gttcccacgg 61621 catggaaaat gtcacttgta gttaatattc tggaagcaag aaaagttccc ttcgaactgc 61681 ttgacaatac ttccggagag agaaacaaaa ctttgaaaaa gctcggaaga attattgatt 61741 ttcttgctgt accggaggac ggagaaaagt tttccaacat gataaatgag tgtattctga 61801 ccggcgatta tgacggcccg gtttttgtcg actctgagga cgaaaccagg acgatggggc 61861 agagggagct tttgagtgag tttataaaaa aatatcctgt ggaaaaaatt ctttatcctg 61921 tgggcgggat aattgaaact tctgatgtgc caaaagaact tcttaaaaca aaaatttgga 61981 gagactttac agacagcctt gacacggtca ggcagctttt ggaatttccc aacactgttg 62041 tggaaaagct tattttgttc atagcggaaa agcttagatt tgacagggaa gagagagcca 62101 tagcccagaa agttgccggg gatgtaagat accttatgaa ccagaatccc cgttggaggc 62161 tgagcgacct ggcatttgag cttctaagcc ctaaaaacat gttcaactat tttgccggcg 62221 tcgtttggga cttaaaggga tttgagccga aaccgggagt ggttacggtt gccacatacc 62281 acaagtccaa aggccttgaa tgggatattg tatttcttac cggacttaac aacgccgatt 62341 ttccggtttt gctggatgac aggtttatgg gggaattttg gtttttgaag gagcagtaca 62401 aaaatcccca ggctttgatt aaaagtgaga tggcaaaagt atttgaagga aaaattgtca 62461 aggattcggt tttggaatcg aaactggaaa caatttcaga gagggcaagg cttctttatg 62521 taggtattac ccgggcaaag gaatatctct ttttatcttc ttatgaacaa aacaagggta 62581 aaagggttga acttccgtca aagtattttt ttgaactgag acggtatatt gaggaggccg 62641 gaaaaacatg aacaatgact tgaggttttt taactatttt ttatttaccc agcagtccat 62701 atccaccttt gaaaaatgtc cattgaagtt taaaaagaga tatcttgaag gactcaagtg 62761 gaaaaacgtg attagtgaag aggcaaagag aaggcttgaa atgggcgaaa actttcattt 62821 gatggccaga agatattttt tgggaattga taccggtctc acaaaaggaa tagaaggata 62881 tgaggagctt tcaaaatgga tggaagctct ggaaagctat tttccgaaaa cggatgacgc 62941 attgtacctg cctgagtaca agctcagaat ggcaaaggga actttgagac ttgaagcaaa 63001 ctttgacctt cttgtgataa aaaaagacgg cattgaaata tgggactgga aaacccatgg 63061 caaaaagaat ccggacaagg cagaaaacga gaggttaaag agtgaaaggc ttaaaggaag 63121 ccttcagaca atggtatatc tttttgtgct caaagaacag gcggaaagag tggttcaaag 63181 ggaagttgac tgctcaaaca taaggatgtt ttactggcag ccggaccctg tccgggtttt 63241 ggctgagata aactacagtg acgaaatgca cgaacagttt ggacaagctc taagaagcaa 63301 aatagacggt attttgcatt atgattacga agactttgac aaggaacttt acaaaaagaa 63361 ctgcccctat tgtgaattta actggttttg caacaatgaa cgggttgatt ttgaggccat 63421 ggaagatgat gaagattttc tggatcagct ggattgggac agcattgagg agttgagata 63481 gttgaaagtc agggtgaata tattaaacaa gggagtttcc attccgcagg aagtgctgga 63541 tgcttgcggc ggtgacgagc ttgtggcaag gattttttac aaccggggat ataaaaatcc 63601 ggaaactata aggcagatgc tgaatccaga gctttatgtg ccgacaaagc cggatgaatt 63661 tccggatatg cccagggctg tagacaggat tcttcgtgct gctgacaacg aggaaaaaat 63721 atgtgtgtat ggggactatg atgttgacgg tgttaccagt accgttaccc ttgttgaatg 63781 cctgaatttt tttacatcaa aggtggtcta ccatgttccg gacaggttta cggaagggta 63841 cggcatgaat gaggaaatag tgagaaaact tgctcaggat ggcgtttcat taataattac 63901 ctgtgactgt ggaatttcga atgtcaggga aataactctt gccaaggagc tggggatgga 63961 tgtggtgctt accgaccatc ataccgttcc cgacgaactt cctcctgccg atgccatatt 64021 aaatcccaag cttttggaag aggggcacag ggcaaggaat atctccggct gtgggatggt 64081 gtatttttta tgccttgcct tgcttgagaa aaagggcttt cctgacaggg cggaaagatt 64141 tctggacatg cttgcgctat cccttatagc ggatgttgtg agccttaacg gagagaacag 64201 gtaccttctt caaaaagctc tgccggcttt gtttaatacc agaagaattg ggctcagaca 64261 gcttcttgag gtggcggaaa gaaacggaaa gcttgaaaat gaggaagatg ttgcatttca 64321 gatagcgccc agaataaatg cggcgggaag gatggacacg gcacggcttc ccgtggagct 64381 tttttatgtc aggacttgga aaaagcacgc attatggctg agaaaattga ctcactgaat 64441 acagaaagaa aaagggtgca gcagtcaatt gtggatgaag ccgtggagat ggtagaaaca 64501 aggaaaaaga acaagacaat tctggtgctg tataaagagt actggcatca tggtataatc 64561 ggaattgctg ccggaaggat ttgcgagctt tatcgaaagc cggcaattct gttttcctta 64621 aaagaagatg gaattacggc agtaggttct gccaggtcca ttgaggaggt aaacatttac 64681 gaactgatta aggaatgcag cggaaagctt ttaaagtttg gaggacactc ccaggctgcc 64741 ggactttcaa taagaaaaga tgatattgag gagtttataa gccagattga gatggaggcg 64801 gaaaacaggt attttataaa agacatggtg aatgtcaatg ccgatatgga acttggcata 64861 gaagatataa atgaagagct ctacgacaga attcaatcgg cgggacctta cggagaaggg 64921 tttgaggctc cttgtttttg cataagaaat gttattgttt taagtgacag aatgacggag 64981 aaaaaacatc atataatggt attggaagat caaaaaggaa acagaatacc tgcagtcaag 65041 tggtttggtg aggatgaatc ctttgagggc aggtgttttg atgtaacctg cagaataggc 65101 cggaacaatt acagcaagga cgcgggtatt caactgactt tggaatatat ggttgaaagt 65161 ttcgggaaat ttaaaaagct gtttgaaggt gaaataatag atgagagaaa aacaactgtt 65221 gaaaacctct taaggaaata tcccaatgcc caaatattct acgaagggct tcagacggca 65281 tgtcccgttg agaataccat tgacaggttt tcggtgaaaa actgtaagga gcttgttttt 65341 ttgtccaccc ctgcgaatac tgagattttc aaagaggtta ttgcccttgc caatccagaa 65401 aaggtgataa taaattttgc cgtcctttcg aactatacct ttaaaggctt tgtattaaac 65461 cttttggggc ttataaagca cataataaag agacgggacg gaagagctta tattgatgag 65521 ctttctttga agctttgcgt tgaggagaac attgtaaaag cgggattaaa atatcttggc 65581 tcttctggaa tgttaaacta tactttaagt gacgatgagc aaaaagttta tttgtctgaa 65641 ggaaaaggtg tggctgacag aaatgctttt atggcgaaaa aaaacctttt tcgacgcttt 65701 ggcggaaaag aatgcctatc agcagtttat tttaaagatg gagatagata aattcaggga 65761 atatcttaag taattcggtt aagtgatgca aaaatagcgt tcttccgtca tatccgcctt 65821 cttttattac ttttacaaca ccgtttaatt cctctttgat attttcaaaa tgtatgataa 65881 accgttagtt agtgttatca taccgacatt taacagggaa aagctgttac ctaaaaccat 65941 tgattcagtt ataaatcaga cctatgaaaa ctgggaattg ttgattgtgg atgacaagag 66001 tactgatgat acaaaaaaag tagttatgga ttatgcaaaa aaagataata ggatcaaata 66061 cttactaaat aacggaaata agggccccgg tgctgccaga aattttggaa tcaataattg 66121 taatggtaag tatattgcgt ttttagattc agatgatcaa tggttaaaaa atcattagag 66181 atcaatttca tggccttcat gttgaactgc ttaaacataa gtttggttat ttttgcaata 66241 aacggtaagt tataaaaagt ggcttgtatc ctttaaacgc cagattttat atttcaccgt 66301 aagaacaaac gaagctgttt ttgaaaaata caaagaaaac tgatttgtct cagacaattt 66361 ttttacatga attacgcttg actatctgaa cattcaccgt tttttgtctg ttttttatct 66421 ccttattatt aatagaatca agcaataatt caatcgagca ttttgctatc tcaggcaatg 66481 aaacattgac tgtggtaaga ggcggggaca tgtattggga tatatatgaa ttgtcgaatc 66541 ccataaccga aatatcctcc ggaattttaa gcccgtattc ttttattgcc ctgtatgctc 66601 cgatagccat ggtatcattg cttgtaaata cggctgttgg cttttttccg gatgccaata 66661 tttttttcat accctcatag ccgctatttt cagtaaaatc cccatatgca ataaaatcat 66721 tgtttaacgg aaggccgtgc cttaaaagcg catctttgaa gctttcaaat cttatcttac 66781 cagaaagctt gttcagatct cctgtaatta cggcaatgtc tttgtgccca agttcaacaa 66841 gataatctat tgcatcggat acaccgccat aattattgat atttacagac atgactgtgc 66901 ctgtattttc tttttccata tctaaatcaa ctgcgacagt aatagaatct ttatccatta 66961 tttcaaaaat tttactataa tcaatgctgc tgcttcctat tatcaccgca ccgtcaattc 67021 ttttctcata aaaagcgctt tgaatcttcc aaagctcatc cgaactgtat atagttgaca 67081 ccaaaacgtg gtactgggct ttgtttgact ggtcaataaa agcatttata aaaggtgaaa 67141 aatatgaatt gccgtataaa aggtcttcat tattttctat tacatggtgc ggtttttcat 67201 tgtcttttat gtctataata aaaattccca atgtggagct tttcattcct gcaagtcttc 67261 tggccgaagc attaggataa tagttgtatt cttttattgc ttttaatacc ttttcccggg 67321 ttgcctgagg aatgtcagga tagttgttta ttacccgtga gacggtactt cttgaaactc 67381 cgacgatttt tgctatatcc ttgctgttca tgccacacca ccttcatatc aaaaacttaa 67441 aatcagcctt ttaagtaaag aatagcactg atacgaaaat ttatcaagtg gttttactgt 67501 ttctggatat attgaaaata atttgaattt tttgcagatc aagaatttag aatgatattc 67561 ttttttatct aggcttggtt ttagttgaca atctgaagtt tataggatat aattaaatcg 67621 aattaacgcg tgttagtggc ttaaaataca gggtttgacg tttatatata tttctttgaa 67681 ttgttacagg agctttgctg aagtgttaat ttttaccgcc gctaaagtat aaaaatatat 67741 tttatttata ttattttacg ggaggtattt tttatgaaaa acagggtaat ttcattatta 67801 atggcttcct tgcttttggt tttgtcggta attgttgctc ctttttacaa agcggaagcc 67861 gcaactgtgg taaatacgcc ttttgttgca gtgttttcga actttgactc cagtcagtgg 67921 gaaaaagcgg attgggcgaa cggttcggtg ttcaactgtg tttggaagcc ttcacaggtg 67981 acattttcga acggtaaaat gattttgacc cttgacaggg aatatggcgg ttcatatccg 68041 tataaaagcg gtgaatatcg tacaaaatca tttttcggat acggttatta tgaagtaaga 68101 atgaaagctg ccaaaaacgt aggaattgtt tcatctttct tcacttatac aggaccttcg 68161 gacaacaatc catgggacga aatcgatatc gagtttttag gaaaggacac aactaaagtt 68221 cagttcaact ggtacaaaaa tggagtcggt ggaaacgagt atttgcacaa tcttggattc 68281 gatgcttccc aggattttca tacatatgga tttgaatgga ggccggatta tatagacttc 68341 tatgttgacg gcaaaaaagt ttatcgtgga accaggaaca tacctgttac tcccggcaaa 68401 attatgatga atttgtggcc aggaatagga gtggatgaat ggttgggacg ttacgacgga 68461 agaactcctt tgcaggcgga gtacgaatat gtaaaatact atcctaacgg tgttccgcaa 68521 gataatccta ctcctactcc tacgattgct ccttctactc cgactaaccc taatttacct 68581 cttaagggag acgtaaacgg cgacggtcat gttaactcat cagactattc attatttaaa 68641 agatatttgc tcagggttat tgatagattc cctgttggag atcagagtgt tgctgatgta 68701 aacagggacg gaaggattga ctccacagac cttacaatgt taaagagata tctgatacgg 68761 gcaattccgt cactttgaaa ttaattcttc tcaaaacccc ataaataaat caaaccccat 68821 tataaaaact ctgtaattta tgaaaat //