LOCUS NZ_ACVX01000025 55541 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00070, whole genome shotgun sequence. ACCESSION NZ_ACVX01000025 NZ_ACVX00000000 VERSION NZ_ACVX01000025.1 GI:256005164 DBLINK Project: 55637 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. REFERENCE 1 (bases 1 to 55541) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE The draft genome of Clostridium thermocellum DSM 2360 JOURNAL Unpublished REFERENCE 2 (bases 1 to 55541) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Larimer,F., Land,M.L., Hauser,L. and Hemme,C.L. CONSRTM US DOE Joint Genome Institute (JGI-PGF) TITLE Direct Submission JOURNAL Submitted (17-JUL-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000025. URL -- http://www.jgi.doe.gov JGI Project ID: 4085028 Source DNA and Bacteria available from Christopher L. Hemme (hemmecl@ou.edu) Contacts: Christopher L. Hemme (hemmecl@ou.edu) David Bruce (microbe@cuba.jgi-psf.org) Whole genome sequencing and draft assembly at JGI-PGF Annotation by JGI-ORNL The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##Metadata-START## Organism Display Name :: Clostridium thermocellum DSM 2360 Culture Collection ID :: DSM 2360 GOLD Stamp ID :: Gi02594 Isolation Site :: contaminant of Clostridium thermocellum strain LQ8 Isolation Country :: USA Oxygen Requirement :: Anaerobe Cell Shape :: Rod-shaped Motility :: Motile Sporulation :: Sporulating Temperature Range :: Thermophile Temperature Optimum :: 60 C Gram Staining :: gram+ Biotic Relationship :: Free living Diseases :: None Phenotypes :: Cellulose degrader, Ethanogenic, Ethanol production Energy Source :: Chemoorganotroph ##Metadata-END## FEATURES Location/Qualifiers source 1..55541 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene <1..199 /locus_tag="ClothDRAFT_1994" CDS <1..199 /locus_tag="ClothDRAFT_1994" /inference="similar to AA sequence:KEGG:HCH_02073" /note="KEGG: hch:HCH_02073 rhs family protein" /codon_start=2 /transl_table=11 /product="rhs family protein" /protein_id="ZP_05430133.1" /db_xref="GI:256005165" /db_xref="InterPro:IPR006141" /translation="DFVEAGKLQVGDKLLDSKGNVLVVEDKKLEITDEPVKVYNFKVD DFHTYHVGNNGILVHNANNLS" misc_feature <5..184 /locus_tag="ClothDRAFT_1994" /note="Protein of unknown function (DUF1557); Region: DUF1557; pfam07591" /db_xref="CDD:148935" gene 180..425 /locus_tag="ClothDRAFT_1995" CDS 180..425 /locus_tag="ClothDRAFT_1995" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430134.1" /db_xref="GI:256005166" /translation="MQIIYLKDPNKLLENGWEDVTPECIRKNTNSRILYYDPKTGTKV RFDLKAEEVPGYNGKDHYHIYNPDFTLVNMIITLTLT" gene 484..822 /locus_tag="ClothDRAFT_1996" CDS 484..822 /locus_tag="ClothDRAFT_1996" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430135.1" /db_xref="GI:256005167" /translation="MLKYNFHDSLIEDVNYIPNEAKLEIKIKLCNWMQSDYKDSDPEM LTMHMIFDGVEKFEMSTENYVFNSNEILDVIELDDRTVKIIFLTENDVKTIIVTAERV DYAIYENEQS" gene 1340..1903 /locus_tag="ClothDRAFT_1997" CDS 1340..1903 /locus_tag="ClothDRAFT_1997" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: viral A-type inclusion protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430136.1" /db_xref="GI:256005168" /translation="MDYSYLYQRAKSRYYEACAEITSCQNKIDDLKKQQQQKINLINQ LKTDIKNHEEALDKVKEIIKSEGNFENKISDISNKTNEAAINYSSMVSCSNVVNKNLN EVYGDEMRNTKKTINDIFTNFKTRKNELETKIADLKRQLQQAENDLDEIKRNITLTEN RLQDWKRAKTQASYDMEYYRRKMNQAV" gene 2065..3588 /locus_tag="ClothDRAFT_1998" CDS 2065..3588 /locus_tag="ClothDRAFT_1998" /inference="protein motif:PFAM:PF07719" /note="PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="Tetratricopeptide TPR_2 repeat protein" /protein_id="ZP_05430137.1" /db_xref="GI:256005169" /db_xref="InterPro:IPR001440" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR013105" /translation="MNINVKDIIADSHLAFLNQENETALRLARQAISLAPDNPDAYRC AGNACMSLDRYDEAIEYYRTAVKYDPDNGNRYYDLGFALASAERFSDALKNLAKAEEL GCTPENLVQLYNLLGILCFDIGRYDDALVNLNKAEKLIGIDVDILKRKAVIYGIKNDI KNGLMTANQIKLVTPSEYTGYQIAFKLLVQAKRLDEAEKELERARKYASPTMDFYFDY MTLELEKYKTDNDKEHFKTALGMIEKALKTVKPTVKEVVESYINAAEIYLQLEDADRA IECLNAAQNPIWAYNNGFDVVVRNYEPVTLTEYDIEDMIEADRKKIEEQFGDYGFEEM VESIEPDEEGNRDYLTVIEDEVKSDAKEDSEVYKLDESEKVEYSSDNIDQINRLYVGA YTVKKDFEKVIEYSRKLQASENTYSVYLGKYTEANAMKELGLPDFAAKYEEIIKFFRN AMIKDPTDLTAVTFRVQCYIDIGQYDEAEQLCSLLTKEVRNSFMEKIKKAKSGGEQH" misc_feature <2101..>2676 /locus_tag="ClothDRAFT_1998" /note="putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917" /db_xref="CDD:163072" misc_feature 2101..2370 /locus_tag="ClothDRAFT_1998" /note="Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi...; Region: TPR; cd00189" /db_xref="CDD:29151" misc_feature order(2101..2106,2191..2196,2200..2205,2212..2217, 2293..2298,2305..2310,2317..2322) /locus_tag="ClothDRAFT_1998" /note="binding surface" /db_xref="CDD:29151" misc_feature order(2134..2136,2146..2148,2155..2157,2200..2202, 2236..2238,2248..2250,2257..2259,2302..2304,2338..2340, 2350..2352,2359..2361) /locus_tag="ClothDRAFT_1998" /note="TPR motif; other site" /db_xref="CDD:29151" gene 3585..3905 /locus_tag="ClothDRAFT_1999" CDS 3585..3905 /locus_tag="ClothDRAFT_1999" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430138.1" /db_xref="GI:256005170" /translation="MKLKQDIVLDDMAFHTASAEMKALKERTEALRTKLEEMYKDLTT ALDTPAGRQVKITAEEVLLKPIDDFLLVIQHVSDTLAEIIGTGYYKDIFIKFEQLNES IKFD" gene 3930..4259 /locus_tag="ClothDRAFT_2000" CDS 3930..4259 /locus_tag="ClothDRAFT_2000" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430139.1" /db_xref="GI:256005171" /translation="MAMGSTGTIHMTPEMLQNAMQAIEDYKATTDNLKTQLDNTINTL LSSSFSGNAAEGFKFFYDNTIRPAIEEGLSSLLTTLNDIMDGILKAIPGENGLDDQLG EQNRQQG" misc_feature 3975..>4217 /locus_tag="ClothDRAFT_2000" /note="Uncharacterized conserved protein [Function unknown]; Region: COG5444" /db_xref="CDD:35003" gene 4277..4582 /locus_tag="ClothDRAFT_2001" CDS 4277..4582 /locus_tag="ClothDRAFT_2001" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430140.1" /db_xref="GI:256005172" /translation="MAGCRIVNQGMLDAISEIQRIAGEYETVADEFISSLNNAISEME GETKDALYELINSKVKTFVYQDLPAALRGMAELLEANRQNFENTDKQLAGSISSSEG" misc_feature 4364..>4579 /locus_tag="ClothDRAFT_2001" /note="COG (conserved oligomeric Golgi) complex component, COG2; Region: COG2; pfam06148" /db_xref="CDD:148010" gene 4698..6077 /locus_tag="ClothDRAFT_2002" CDS 4698..6077 /locus_tag="ClothDRAFT_2002" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: similar to Titin (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430141.1" /db_xref="GI:256005173" /translation="MAFRILSEEEVSLLDEEQRKQYEKELRIYRQRAAFVEQIEAYEK VRIPPYEPDLKPITVMKKFEVKPYTRPEYTVAEYKPVEKPELPIKPFKPAETGNPVLP EISKPVSTDISPVKKVENVETELQTVDKPVIPKLRFEKLEGEYPDLPVIPKINVVNKS YKGTREVKVNLPEVVKPEIQAGFSFKTPGFDSSGIKASIPEISVSGVSLKPFVTPEKS LSDLPQVKVCHAQVKAFRNPEQTGTVLPQVTRPYIDVNYVKNEKSVRLSLPELRNISK VSMVFKKPEKSEAGIPSFVKPKVRIAAFRKTELNRVDLPEKYRIDIKRTVFSKPEIQF SALPQVAKLEYKVQSFKRAELQVPVLSPVSKVGSDIRTFKKPEYKNFVLPVIPKISIV TENFKQVKVTQPHVALGPDTVVSPSIKLKPFEKVENKAVGLPEGITVNIPDVSEELEQ LLQSKKNDK" gene 6101..9301 /locus_tag="ClothDRAFT_2003" CDS 6101..9301 /locus_tag="ClothDRAFT_2003" /inference="protein motif:PFAM:PF01580" /note="PFAM: cell divisionFtsK/SpoIIIE; KEGG: gsu:GSU3112 cell division protein FtsK, putative" /codon_start=1 /transl_table=11 /product="cell divisionFtsK/SpoIIIE" /protein_id="ZP_05430142.1" /db_xref="GI:256005174" /db_xref="InterPro:IPR002543" /translation="MKNNEIMISVKFESDDFSDELSFLVIKDISLKALIEAIYYGLKK AKGYEKHFNLVDKYLKTRKELQVLYNAKGDFNVIDFTEEVDGTKIFNKKLDELGFVTS SCILFTTDTKVAPKPLFQKNERSYILKSGNSLEYNISTRRLNVIEPSVIEIIPPGEMP KKDKSSYLDIIIPTVLSTGGMLMARYLIILFAPKAASLGNTMLLMSGAMGVVALVTST YNFMKQRNNYKKDVQVWKENYENYIHRIIKRIKEWQKSDIKYLNSVYPNMDTLFKNTA EIHSSIFSRSQNDKDFMVISLGMSDEVKPLFEIKSEKKDHIFYDIYYKKIGDRIEIIL PSKKEKRRKKLSPAERAEEDKNRFLLTDLAYNFANKDGDIGFKYLRSDDGSKPPLLLD LKSCGTLGVISEDIQTSRNFIQHVVFELAYYHSPEDLQFVFFFEPEDDPTKQNEILQN YKYLPHANELFDGVSQFVFDKESAGIVFGQLLGIMNERVKSSGDKNEGVNQNQKLTQI VCIVFYDYNIKETGFSKFLPEVPKEGEPYVNSNGLTFIFIQPVKDKLPKYCGNIVEIH KDNPNARRCSLRYNILSRETLNVLSEGDDDTSKASDTDKLIEYKHFQNNYIFNAEKYR EKFALAFKQLSAIYYTRIAENGKVPSMVTLFELYGFDSEKVQKGEIKKIILDNWKDIE KNDVTRSLGVPIGKNEHGPIYLDLHEKADGPHMLVAGMTGSGKSETIITLLIGLCMKF SPMDLNLMLVDMKGGGFSDRLGDLPHCVGVVTDTTGEEEGTSAAYMLKRFLESLNAEI KRRKLLLSSLGVDNIDAYIRALRIIRQIKELEGKPGTEETIEKLKKKLNDKQLKALNK DLKEFSYLSHLILVVDEFTELKRFSSESSDTDFIAEITTIARVGRTLGFHIILISQNI EGAITDDIRLNSKARICLRVATKQASKEMIDSPAAAAPTMPLNGRAYLLVGTGTRFEY FQSAYTGANKNLNIEPPVVVTQVPNSGRFNTDFYSSKKDNEREKKKNENVNEHDTQLR YINNTIIEMSREMEKPRQIFLPPLSEKIFDETKWRY" misc_feature 8105..8836 /locus_tag="ClothDRAFT_2003" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" misc_feature <8690..>9094 /locus_tag="ClothDRAFT_2003" /note="DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674" /db_xref="CDD:31860" gene 9304..11040 /locus_tag="ClothDRAFT_2004" CDS 9304..11040 /locus_tag="ClothDRAFT_2004" /inference="protein motif:COG:COG1674" /note="KEGG: bpt:Bpet4245 hypothetical protein" /codon_start=1 /transl_table=11 /product="DNA segregation ATPase FtsK/SpoIIIE-like protein" /protein_id="ZP_05430143.1" /db_xref="GI:256005175" /db_xref="InterPro:IPR002543" /translation="MAFEKMLCTLGKFDIPIIQLQPPFVVDLLDSNIAVFGAAMSGKT TFIRTLVNVLHKQYNEKEEQIFILDFGGALFDCRDLPLVSAYFDNSNEEYVKRVFKIM DNILKDNIRELNGKNFRDADVQPLHTTFIIDNVNAFIDEPRYMAYHEKLAKLCREGLS KGITIVITALDTKGVTSYLGNFKQKIAFELPVEKYADIFTGKVGLIKNTPGRGFANVT VKPEGVTGTFRMNLPYEVQCALPYRTEDAEESGDTKESFYEKLRQKFSFSEGRYRKCV KKYWTFPKELTWEEYEKLKQQPKNEQKEYRLPVSVGLDYVNFYPVTVDLEQSRVIAIY GKKGFGKTNLLYLLLSGVVQQRPEAEIVFFDDGRNQLEPVYNSFKDKVNCKLINKFEE MELCLTDGTKKMRKLSPLQQFYLYLNEKHISLDKPNYMADIYGVSKVSSKEYLMIPDC YVERAPFTVFVIQSKLVYLNAVENKRFINVLLPQLVSVAEERGYLFIFSDVQKISDAE QNSFFNNMITGAFLLDNIAEFAGERGQRTIFGNMDVKSLKEDYARCEIGDGYFYDVEA DNLLKLKFIKYC" misc_feature 9328..9810 /locus_tag="ClothDRAFT_2004" /note="P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop NTPase; cl09099" /db_xref="CDD:158411" gene 11055..11381 /locus_tag="ClothDRAFT_2005" CDS 11055..11381 /locus_tag="ClothDRAFT_2005" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430144.1" /db_xref="GI:256005176" /translation="MTDSGFVLADIDKLVQFEKKSEEAIEEFDAIKKEFERINETLLS KWKGEGADAYRQETDNILANIGGIRDVLDAINNGAVKAIKESYLKLDEELGKFNRNPH VDREDG" gene 11417..11557 /locus_tag="ClothDRAFT_2006" CDS 11417..11557 /locus_tag="ClothDRAFT_2006" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430145.1" /db_xref="GI:256005177" /translation="MPKPSIGTAQIPVPEKEEKPVIQELTVLEEGSKESIYNLIFSEE EK" gene 11767..12330 /locus_tag="ClothDRAFT_2007" CDS 11767..12330 /locus_tag="ClothDRAFT_2007" /EC_number="1.11.1.15" /inference="protein motif:TFAM:TIGR03137" /note="KEGG: aci:ACIAD2103 alkyl hydroperoxide reductase, C22 subunit, thioredoxin-like (detoxification of hydroperoxides); TIGRFAM: peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein" /codon_start=1 /transl_table=11 /product="peroxiredoxin" /protein_id="ZP_05430146.1" /db_xref="GI:256005178" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013740" /db_xref="InterPro:IPR017559" /translation="MSLIGTEVKPFTAEAYHNGKFITVTEQDFKGKWSIVVFYPADFT FVCPTELEDLQNNYEKFKALGAEVYSVSTDTHYTHKAWHDTSEAIKKITYVMIGDPSH TLSRNFDVLNEATGLADRGTFIIDPDGVIQYVEVSAENVGRNAEALIDKIKAAQYVRN HPGEVCPAKWKEGGATLKPSIDLVGKI" misc_feature 11767..12327 /locus_tag="ClothDRAFT_2007" /note="peroxiredoxin; Region: AhpC; TIGR03137" /db_xref="CDD:163149" misc_feature 11776..12285 /locus_tag="ClothDRAFT_2007" /note="Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic...; Region: PRX_Typ2cys; cd03015" /db_xref="CDD:48564" misc_feature order(11776..11778,11899..11904,11911..11913,12091..12093, 12121..12123,12160..12168,12172..12180,12190..12195, 12214..12216,12262..12273) /locus_tag="ClothDRAFT_2007" /note="dimer interface; other site" /db_xref="CDD:48564" misc_feature order(11893..11895,11995..12000,12064..12066,12070..12072, 12106..12108) /locus_tag="ClothDRAFT_2007" /note="decamer (pentamer of dimers) interface; other site" /db_xref="CDD:48564" misc_feature order(11896..11898,11905..11907,12124..12126) /locus_tag="ClothDRAFT_2007" /note="catalytic triad; other site" /db_xref="CDD:48564" misc_feature order(11905..11907,12262..12264) /locus_tag="ClothDRAFT_2007" /note="peroxidatic and resolving cysteines; other site" /db_xref="CDD:48564" gene 12344..13873 /locus_tag="ClothDRAFT_2008" CDS 12344..13873 /locus_tag="ClothDRAFT_2008" /inference="protein motif:TFAM:TIGR03140" /note="TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: dia:Dtpsy_2368 alkyl hydroperoxide reductase, F subunit" /codon_start=1 /transl_table=11 /product="alkyl hydroperoxide reductase, F subunit" /protein_id="ZP_05430147.1" /db_xref="GI:256005179" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR000759" /db_xref="InterPro:IPR001327" /db_xref="InterPro:IPR003042" /db_xref="InterPro:IPR004792" /db_xref="InterPro:IPR008255" /db_xref="InterPro:IPR012081" /db_xref="InterPro:IPR013027" /translation="MFLDAEIMQQLEQYLTLLENDIVIKVNAGNDKVSVDMVRLIDEI AKLTPKIHVEKAELDRTPSFSVNRPNEDTGIVFAGIPLGHEFNSLVLALLQVGGRAPK VDEALINQIKGIKGEYHFETYVSLSCHNCPDVVQALNIMSVLNPNITHTMIDGAVFRE EVESKGIMAVPTIYLNGNFFESGRLTLEEILAKLGQATESPSINEKEPFDVLVIGGGP AGVSSAIYAARKGLRTGIIAERFGGQILDTLGIENFISVPYTEGPKLAENFKEHVKRY DIDVMERQRAKSIRRNELLEVELEKGAVVKSKTVIIATGARWRNVNVPGEKEFKNKGV AYCPHCDGPLFAGKDVAVIGGGNSGIEAAIDLAGIVRHVTVLEFLPQLKADKVLQERL YRLPNVTVLTNVQTKEFTGKEKLDGITYIERDTNQEKHIEVQGVFVQIGLVPNTEWLE GTIERNAMGEIIVNEKNETSMPGVFAAGDCTNSPYKQIVIAMGSGATAALSAFDYLIR N" misc_feature 12347..12625 /locus_tag="ClothDRAFT_2008" /note="Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the...; Region: AhpF_NTD_N; cd02974" /db_xref="CDD:48523" misc_feature 12350..13870 /locus_tag="ClothDRAFT_2008" /note="alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317" /db_xref="CDD:185217" misc_feature 12596..12598 /locus_tag="ClothDRAFT_2008" /note="catalytic residue; other site" /db_xref="CDD:48523" misc_feature 12656..12922 /locus_tag="ClothDRAFT_2008" /note="TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026" /db_xref="CDD:48575" misc_feature order(12725..12727,12734..12736) /locus_tag="ClothDRAFT_2008" /note="catalytic residues; other site" /db_xref="CDD:48575" misc_feature 12968..>13057 /locus_tag="ClothDRAFT_2008" /note="Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl10040" /db_xref="CDD:186896" misc_feature 13391..13600 /locus_tag="ClothDRAFT_2008" /note="Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; cl14644" /db_xref="CDD:187400" gene 14469..16982 /locus_tag="ClothDRAFT_2009" CDS 14469..16982 /locus_tag="ClothDRAFT_2009" /inference="protein motif:PFAM:PF00331" /note="PFAM: glycoside hydrolase family 10; Carbohydrate binding family 6; putative esterase; cellulosome protein dockerin type I; SMART: glycoside hydrolase family 10; cellulose binding type IV; KEGG: endo-1,4-beta-xylanase, putative" /codon_start=1 /transl_table=11 /product="glycoside hydrolase family 10" /protein_id="ZP_05430148.1" /db_xref="GI:256005180" /db_xref="InterPro:IPR000801" /db_xref="InterPro:IPR001000" /db_xref="InterPro:IPR002048" /db_xref="InterPro:IPR002105" /db_xref="InterPro:IPR005084" /db_xref="InterPro:IPR006584" /translation="MSRKLFSVLLVGLMLMTSLLVTISSTSAASLPTMPPSGYDQVRN GVPRGQVVNISYFSTATNTTRPARVYLPPGYSKDKKYSVLYLLHGIGGSENDWFEGGG RANVIADNLIAEGKIKPLIIVTPNTNAAGPGIADGYENFTKDLLNSLIPYIESNYSVY TDREHRAIAGLSMGGGQSFNIGLTNLDKFAYIGPISAAPNTYPNERLFPDGGKAAREK LKLLFIACGTNDSLIGFGQRVHEYCVANNINHVYWLIQGGGHDFNVWKPGLWNFLQMA DEAGLTRDGNTPVPTPSPKPANTRIEAEDYDGINSSSIEIIGVPPEGGRGIGYITSGD YLVYKSIDFGNGATSFKAKVANANTSNIELRLNGPNGTLIGTLSVKSTGDWNTYEEQT CSISKVTGINDLYLVFKGPVNIDWFTFGVESSSTGLGDLNGDGNINSSDLQALKRHLL GISPLTGEALLRADVNRSGKVDSTDYSVLKRYILRIITEFPGQGDVQTPNPSVTPTQT PIPTISGNALRDYAEARGIKIGTCVNYPFYNNSDPTYNSILQREFSMVVCENEMKFDA LQPRQNVFDFSKGDQLLAFAERNGMQMRGHTLIWHNQNPSWLTNGNWNRDSLLAVMKN HITTVMTHYKGKIVEWDVANECMDDSGNGLRSSIWRNVIGQDYLDYAFRYAREADPDA LLFYNDYNIEDLGPKSNAVFNMIKSMKERGVPIDGVGFQCHFINGMSPEYLASIDQNI KRYAEIGVIVSFTEIDIRIPQSENPATAFQVQANNYKELMKICLANPNCNTFVMWGFT DKYTWIPGTFPGYGNPLIYDSNYNPKPAYNAIKEALMGY" sig_peptide 14469..14555 /locus_tag="ClothDRAFT_2009" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.604 at residue 29" misc_feature 14607..>15152 /locus_tag="ClothDRAFT_2009" /note="Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031" /db_xref="CDD:187168" misc_feature 14640..15275 /locus_tag="ClothDRAFT_2009" /note="Putative esterase; Region: Esterase; pfam00756" /db_xref="CDD:144380" misc_feature 15348..15725 /locus_tag="ClothDRAFT_2009" /note="Carbohydrate binding module (family 6); Region: CBM_6; cl02697" /db_xref="CDD:155061" misc_feature 15858..15920 /locus_tag="ClothDRAFT_2009" /note="Dockerin type I repeat; Region: Dockerin_1; pfam00404" /db_xref="CDD:144118" misc_feature 16020..16970 /locus_tag="ClothDRAFT_2009" /note="Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495" /db_xref="CDD:154432" gene complement(17081..18043) /locus_tag="ClothDRAFT_2010" CDS complement(17081..18043) /locus_tag="ClothDRAFT_2010" /inference="protein motif:TFAM:TIGR00005" /note="KEGG: ank:AnaeK_0061 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein" /codon_start=1 /transl_table=11 /product="pseudouridine synthase, RluA family" /protein_id="ZP_05430149.1" /db_xref="GI:256005181" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR006225" /translation="MRTITITEDKANKRIDKVLRETFPRLPNGALFKAFRKKDIKVNG VRVKEDHIVKLNDRVDIYIIDEILDGVPKAGELNYETAFSVAYEDSNLLIVNKKQGIP VHPDRTQTENTLIDFVKEYLKLKGEFEENSGFTPSLCHRLDRNTGGLVMIAKNSSTLH MVLKKMKSGEISKYYQCLVKGKMEKKEDILKAYLEKDEKKSRVFIKDTKSKNAVEIIT GYKVLSYKELPDIGEGISNLEVTLYTGRTHQIRAHLAHIGHPVVGDGKYGINTFNRLL GAKYQALWAYKLKFDFKSDAGILNYLRGKVIQVQPEYKLSKSWK" misc_feature complement(17174..18043) /locus_tag="ClothDRAFT_2010" /note="Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564" /db_xref="CDD:30910" misc_feature complement(17174..17770) /locus_tag="ClothDRAFT_2010" /note="PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF...; Region: PseudoU_synth_RluCD_like; cd02869" /db_xref="CDD:30029" misc_feature complement(order(17291..17293,17615..17626)) /locus_tag="ClothDRAFT_2010" /note="active site" /db_xref="CDD:30029" gene complement(18080..20530) /locus_tag="ClothDRAFT_2011" CDS complement(18080..20530) /locus_tag="ClothDRAFT_2011" /inference="protein motif:PFAM:PF00483" /note="PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; KEGG: gur:Gura_0855 nucleotidyl transferase" /codon_start=1 /transl_table=11 /product="Nucleotidyl transferase" /protein_id="ZP_05430150.1" /db_xref="GI:256005182" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR005844" /translation="MKAIIMAGGEGSRLRPLTCDLPKPMVPIMNIPIMEHIINLLKKH GITEIGVTLMYLPQKIKDYFGNGSNFGVNITYFTEDTPLGTAGSVKNAEDFLDETFIV ISGDSLTNMNITKAIEFHRMKNSKATLVLTRVDVPLEYGVVITDKSGAITGFLEKPSW GEVFSDTVNTGTYILEPEILKYLEKGKKVDFSQDLFPYLLLKKEPMYGYVMDDYWCDI GDLQAYLQAHYDVLEGKIQLDINGTEIQKGVWVGSGAIIEPGAILNPPCVIGDNCRIE SGAVIDSLSVIGNNNVIERDSSVKRSVIWDGNYIEYGSEIRGAILCSKTNLKRYVHIF ENAIVGDNCLINERVVIKPNIKIWPQKTVEPFAIVDRNIIWGSKHSKSIFGENGLSGI INVDISPEFATRLGAAYGSIFKKGSKVVVSSTTANSARMFKHAFISGILSVGVEVFNL SSLLTPLARHAINFLSVEGGIHIKLSEDNPNKLKVDFMDSKGASISRVTERKIENSFA REDFKRCSGDEVSRLNNITDFKNYYVRSILNEVNVEAIKNNPPKLCIVSPSDFVISIV VPMLTDLGCKVASFSSTNVSEVDTIVDEIKDNNASFAAFIDSNGETLVLIDKNGNVVK DDLFLCLTSLITFKSVPNSKVVVPITAPSIIETLAERYNGKVVRTKTSPQAVMEQMLN HNLFKNRENMYQFLLNFDAIAGLVKIIEFLCLQNTTLTETIKEIPDFYVSKKKIFCPW ELKGRVMRTLITEKDQEKVELLDGVKFILENGWALVLPDADMPLCRVYSEGVTPEVAE TISDKYIDKIKAIINDKK" misc_feature complement(19421..20530) /locus_tag="ClothDRAFT_2011" /note="Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208" /db_xref="CDD:31401" misc_feature complement(19874..20524) /locus_tag="ClothDRAFT_2011" /note="NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181" /db_xref="CDD:133024" misc_feature complement(order(20024..20026,20210..20215,20219..20221, 20294..20296,20459..20464,20504..20515)) /locus_tag="ClothDRAFT_2011" /note="active site" /db_xref="CDD:133024" misc_feature complement(order(20213..20215,20219..20221,20375..20377, 20507..20515)) /locus_tag="ClothDRAFT_2011" /note="Substrate binding site; other site" /db_xref="CDD:133024" misc_feature complement(order(19874..19876,19880..19882,20213..20215)) /locus_tag="ClothDRAFT_2011" /note="Mg++ binding site; other site" /db_xref="CDD:133024" misc_feature complement(19421..19843) /locus_tag="ClothDRAFT_2011" /note="Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160" /db_xref="CDD:107413" misc_feature complement(order(19421..19423,19427..19429,19433..19435, 19445..19447,19475..19477,19481..19486,19499..19501, 19553..19555,19580..19582,19586..19588,19598..19600, 19604..19606)) /locus_tag="ClothDRAFT_2011" /note="putative trimer interface; other site" /db_xref="CDD:100038" misc_feature complement(order(19421..19423,19439..19441,19475..19477, 19490..19495,19499..19501)) /locus_tag="ClothDRAFT_2011" /note="putative CoA binding site; other site" /db_xref="CDD:100038" misc_feature complement(18137..19393) /locus_tag="ClothDRAFT_2011" /note="Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109" /db_xref="CDD:31306" misc_feature complement(18137..19384) /locus_tag="ClothDRAFT_2011" /note="GTP-mannose-1-phosphate guanyltransferase (MPG1 transferase), also known as GDP-mannose pyrophosphorylase, is a bifunctional enzyme with both phosphomannose isomerase (PMI) activity and GDP-mannose phosphorylase (GMP) activity. The protein contains an...; Region: MPG1_transferase; cd05805" /db_xref="CDD:100097" gene 20947..22029 /locus_tag="ClothDRAFT_2012" CDS 20947..22029 /locus_tag="ClothDRAFT_2012" /inference="protein motif:PFAM:PF01471" /note="PFAM: Peptidoglycan-binding domain 1 protein; KEGG: mxa:MXAN_0560 penicillin-resistant dd-carboxypeptidase" /codon_start=1 /transl_table=11 /product="Peptidoglycan-binding domain 1 protein" /protein_id="ZP_05430151.1" /db_xref="GI:256005183" /db_xref="InterPro:IPR002477" /translation="MQKKKPALFAVILPLLIACIMINSSMVFASSGILKEGMSGSQVT SLQRDLNTLGYLDVTPTGYYGSLTTAAVKKLQRNYGLKEDGIAGPDTLSLIKRLINER TASRSSGGTTLKEGMSGSSVTALQKDLKALGYLSVDPTGYYGSLTKEAVKKLQAKHGL EQDGIAGPKTLALIDRLMGRSGSSASQSAATASRGGLDKTNYLYSWFGNAENIFKIGD TAQVYDIRTGRTFNIKRTYGYNHADCETLTAKDTEIMLSIYGGSWSWERRPIIVIVNG RKMAASMAGMPHAGVDSAPANTYVKSRSGGYGAGDNLDSVKNNNMNGVFDVHFLNSKT HGTNRVDENHQKAVREAAEWAAKNKF" sig_peptide 20947..21036 /locus_tag="ClothDRAFT_2012" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.991 at residue 30" misc_feature 21061..21231 /locus_tag="ClothDRAFT_2012" /note="Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471" /db_xref="CDD:144895" misc_feature 21298..21468 /locus_tag="ClothDRAFT_2012" /note="Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471" /db_xref="CDD:144895" gene 22397..23131 /locus_tag="ClothDRAFT_2013" CDS 22397..23131 /locus_tag="ClothDRAFT_2013" /inference="protein motif:PFAM:PF08241" /note="PFAM: Methyltransferase type 11; methyltransferase small; Tellurite resistance methyltransferase, TehB, core; Methyltransferase type 12; KEGG: scl:sce9032 methyltransferase" /codon_start=1 /transl_table=11 /product="Methyltransferase type 11" /protein_id="ZP_05430152.1" /db_xref="GI:256005184" /db_xref="InterPro:IPR007848" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR013217" /db_xref="InterPro:IPR015985" /translation="MSFYREISKYYDYIFPVGENQLNFIKNCAGKPGGKILDVACGSG GYSVELAKEGYLVTAVDIEEEMVEKVKKKASENGLSINAFKCDMRELEKKIGERFDTI FCIGNSLVHLTSLKEITDVLGQMRRLLAEGGFLVLQIVNYDRIIKYNLDGLPTITNDE IGLEFTRKYRYKKESNIIEFNTSLKIKNGDCETEYNNSVELLPLKSGELAAALRNAGF SAFDFYGDFKYSDYTEDSHLLVVKAR" misc_feature 22499..22816 /locus_tag="ClothDRAFT_2013" /note="S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)...; Region: AdoMet_MTases; cd02440" /db_xref="CDD:100107" misc_feature order(22511..22531,22577..22582,22652..22660,22709..22711) /locus_tag="ClothDRAFT_2013" /note="S-adenosylmethionine binding site; other site" /db_xref="CDD:100107" gene 23214..24179 /locus_tag="ClothDRAFT_2014" CDS 23214..24179 /locus_tag="ClothDRAFT_2014" /inference="protein motif:TFAM:TIGR00629" /note="TIGRFAM: UV-endonuclease UvdE; PFAM: UV-endonuclease UvdE; KEGG: UV-endonuclease UVE-1" /codon_start=1 /transl_table=11 /product="UV-endonuclease UvdE" /protein_id="ZP_05430153.1" /db_xref="GI:256005185" /db_xref="InterPro:IPR004601" /translation="MLVRLGYVAMTMNLKDSSPSGTVTVKTLAGLNEDETRLNKLRKV TAANLHNTLRILRYNKAYNISVYRFTSKLVPLATHPMVSHWDYVGEFRNEFKSLGDFV KENNFRVSAHPDHYTLLNSPSKEVFEASVRDLDYHVKLFEAMGLEDYKYKLVMHIGGL YKNKQTSVERFKENYAILPDRIRKRLIFENDDKIYTARDVLDICKELKVPMVLDVHHH NCVNNGERLEDMLKEIFDTWKDEYFPPKIHFSTPKSKENFRSHADEIDVNEFYRFLQI AKKLKKDFDVMIEAKNKDNALFKLSRELKTFDDIRWIDEGHFEIR" misc_feature 23214..24173 /locus_tag="ClothDRAFT_2014" /note="UV-endonuclease UvdE; Region: UvdE; cl10036" /db_xref="CDD:186895" gene 24264..24461 /locus_tag="ClothDRAFT_2015" CDS 24264..24461 /locus_tag="ClothDRAFT_2015" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430154.1" /db_xref="GI:256005186" /translation="MGTPDTGKIKHSDMLIETIRNASSQMSFDEYAKVTGLDKEFIFA ILNGEIEEVDRETWNRLSLKN" gene 24723..26063 /locus_tag="ClothDRAFT_2016" CDS 24723..26063 /locus_tag="ClothDRAFT_2016" /inference="protein motif:PFAM:PF01547" /note="PFAM: extracellular solute-binding protein family 1; KEGG: hch:HCH_06910 ABC-type sugar transport system, periplasmic component" /codon_start=1 /transl_table=11 /product="extracellular solute-binding protein family 1" /protein_id="ZP_05430155.1" /db_xref="GI:256005187" /db_xref="InterPro:IPR006059" /translation="MRRSKYSLVLSFLCFLAILTVTGCSLGGKVQAPNEYTRVQAAEI EEPAEDVEIEFWTYNDGWKAPINHFQLIHPKIKIKLVKFDFNDMGNVYKKALAAGEGP DILFFDSAYYSQFTTGEYLEDLLKEPYYAGRYEKDFPKDIWESNKSLDGKRLLAMTFL TSPVVTFYRADVMEENGFPSEPEELAKFIEKSENLMAIAKKLKSKGQYIFQMPVDIIN LAGLYSGIFDENLRFVRNSDLFVQALDMAREIKRLDLSIGANIVEEAAKEAVRNGELV MVLGIGSWGTSTIQSYAPDQAGKWRVTAPPLGLKVWYSDTKLAINAQSKYKKWAWLFV EYVATQQEGGENIDMISGYCPARRNLKVMLRENEYFGNQHIQPLIEDLAEEMVQYRQT PLDDRALQIFNEEIFRAIENNVDSQKTIKDIANKVEYELKKDREALLKGKKRVK" misc_feature 24723..26033 /locus_tag="ClothDRAFT_2016" /note="Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182" /db_xref="CDD:32365" sig_peptide 24723..24806 /locus_tag="ClothDRAFT_2016" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.519 at residue 28" misc_feature 24903..25739 /locus_tag="ClothDRAFT_2016" /note="The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398" /db_xref="CDD:187020" gene 26100..27032 /locus_tag="ClothDRAFT_2017" CDS 26100..27032 /locus_tag="ClothDRAFT_2017" /inference="protein motif:TFAM:TIGR03168" /note="TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: avn:Avin_12200 1-phosphofructokinase" /codon_start=1 /transl_table=11 /product="1-phosphofructokinase" /protein_id="ZP_05430156.1" /db_xref="GI:256005188" /db_xref="InterPro:IPR002173" /db_xref="InterPro:IPR011611" /db_xref="InterPro:IPR017583" /translation="MITSVALNPAVDKIYFVDNFEPGRMYRVRQMVKTAGGKGVNVAR VARMLGENVRLTGFKGGETGNWLESQLKKLGVVTRFVEVSGETRTNNNIIDRVRDSET EVLEPGPFISGEDMEKFMEVYKEALSDSKVVVLSGGLPQGVPACCYKALIEEAKNFNI PVILDSGGDALKEGIKAKPNVIKPNLRELGSLIQKELRDMDEIVEALKEINADGIDIS MVSMGDKGAVLCTKDLCLRVKVPHVETVNTIGSGDAMVAGFAAGLARDKTMEECLRLA AACGVSNARFLEIGVVDKNEVEIQKNRVEIERIS" misc_feature 26100..27026 /locus_tag="ClothDRAFT_2017" /note="Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105" /db_xref="CDD:31302" misc_feature 26100..26969 /locus_tag="ClothDRAFT_2017" /note="1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164" /db_xref="CDD:29349" misc_feature order(26226..26228,26238..26240,26256..26258,26262..26264, 26505..26507) /locus_tag="ClothDRAFT_2017" /note="putative substrate binding site; other site" /db_xref="CDD:29349" misc_feature order(26592..26594,26646..26648,26652..26654,26760..26762, 26778..26780,26850..26852,26856..26858) /locus_tag="ClothDRAFT_2017" /note="putative ATP binding site; other site" /db_xref="CDD:29349" gene 27313..29469 /locus_tag="ClothDRAFT_2018" CDS 27313..29469 /locus_tag="ClothDRAFT_2018" /inference="protein motif:PFAM:PF00575" /note="PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; RNA binding S1 domain protein; KEGG: geo:Geob_3018 RNA binding S1 domain protein" /codon_start=1 /transl_table=11 /product="RNA binding S1 domain protein" /protein_id="ZP_05430157.1" /db_xref="GI:256005189" /db_xref="InterPro:IPR000110" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR006641" /translation="MSDIISTLVKEFNLKPFQVENTVKLIDSGNTIPFIARYRKEITG ELNDQVLRQLHERLIYLRNLEARKEEVRRLIDEQGKLTAEITASLEKATTLREVEDIY RPFRPKRRTRATVAKEKGLEPLAEIIMAQELKTGSIEDIAKPFINPEKEVNTVEDALN GAMDIIAEDISDNPHIRSIVRDVFMKQGMIVSKKKKDEDSVYRMYYDFSEPVAKIAGH RVLAINRGEKEEFLQVKIEVPEETLMEQLKAKLVKRPPSITSEYVEKALADSYERLIF PSVEREVRNELTENAEEQAIKVFATNLKNLLLQPPVKGKTVLGLDPAYRTGCKIAVVD ETGKVLDTAVIYPTPPQNKVEEAKEIMKRLIEKHGVDIISIGNGTASRESEIFVAELL KEIDRKVYYMVVSEAGASVYSASKLGAEEFPDFDVALRSAVSIARRLQDPLAELVKID PKSIGVGQYQHDMNQKRLSETLQGVVEDCVNSVGVDLNTASPSLLSYISGINSVIAKN IVEYRETNGKFKRREELKKVKKLGDKTFEQCAGFLRIPDGDNVLDNTSVHPESYEAAK KLLDIMGYSLEDVKNRKLDGLVEKVEKMGIEKVAREIGVGVPTLKDIIKELLKPGRDP RDELPKPMLLTDVLHLEDLRPGMILTGTVRNVADFGAFVDVGVHQDGLVHISELSDKY VKSPMDVVSVGDIVKVRILDVDVERKRISMSMKGVN" misc_feature 27313..29457 /locus_tag="ClothDRAFT_2018" /note="Transcriptional accessory protein [Transcription]; Region: Tex; COG2183" /db_xref="CDD:32366" misc_feature 27334..27906 /locus_tag="ClothDRAFT_2018" /note="Tex-like protein N-terminal domain; Region: Tex_N; pfam09371" /db_xref="CDD:150144" misc_feature 28255..28551 /locus_tag="ClothDRAFT_2018" /note="Uncharacterized protein family (UPF0081); Region: UPF0081; cl00525" /db_xref="CDD:186059" misc_feature <28723..28947 /locus_tag="ClothDRAFT_2018" /note="endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl11430" /db_xref="CDD:187036" misc_feature 29248..29451 /locus_tag="ClothDRAFT_2018" /note="S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin...; Region: S1_Tex; cd05685" /db_xref="CDD:88440" misc_feature order(29272..29274,29296..29298,29326..29328,29332..29334) /locus_tag="ClothDRAFT_2018" /note="RNA binding site; other site" /db_xref="CDD:88440" gene 29554..29937 /locus_tag="ClothDRAFT_2019" CDS 29554..29937 /locus_tag="ClothDRAFT_2019" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430158.1" /db_xref="GI:256005190" /translation="MSNITVNIKKLAKRRDIIIAFAAVTFFYCFIEYNLIFPVILGVT TIGGGNFLDSILHTIQLILGLLSNVKYILYGLAAVTVAALVCGFVLSGCFYKINNFLS NRKRIKTEFFKGVQKHFFEDFCDIL" gene 29924..30418 /locus_tag="ClothDRAFT_2020" CDS 29924..30418 /locus_tag="ClothDRAFT_2020" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430159.1" /db_xref="GI:256005191" /translation="MISFEVILFSILFTIFMLIVTVPAVAITRSFLGGKTELLALTVL FDLITLMVLFFGFMFFRIYMAFWYPAVFNFKDSYFSIGKYAADTYFWKIVVMFLKFDV AFILFEFVLIFLNSVLPVSGALAFLRIFLLMFVNWAVKTLFFIVVTISVFSVFLDFKK KVTE" sig_peptide 29924..30004 /locus_tag="ClothDRAFT_2020" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.797) with cleavage site probability 0.774 at residue 27" gene complement(30473..31177) /locus_tag="ClothDRAFT_2021" CDS complement(30473..31177) /locus_tag="ClothDRAFT_2021" /inference="protein motif:TFAM:TIGR02869" /note="TIGRFAM: spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein; KEGG: pzu:PHZ_c2605 hypothetical protein" /codon_start=1 /transl_table=11 /product="spore cortex-lytic enzyme" /protein_id="ZP_05430160.1" /db_xref="GI:256005192" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR011105" /db_xref="InterPro:IPR014224" /translation="MRKRVLSIIVIITILSILSSAVVFWEEIYSLYGYSKAALSYYGS TGQEVKNIQYKLAIWKYYNGKIDGIYGYKTYMAVRKFQAKNGLKVDGIAGPETLAALG LPTGQAAKATSAQPSSNRNLDLLAHLVYGEARGEPYIGQVAVAAVVINRTRDSRFPNT IAGVIYQPGAFDAVSDGQINLAPNETAYKAAKDALNGWDPTGGALYYYNPRTATSKWI WSRKIVKVIGKHNFAI" sig_peptide complement(31112..31177) /locus_tag="ClothDRAFT_2021" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.860 at residue 22" misc_feature complement(30479..31057) /locus_tag="ClothDRAFT_2021" /note="spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869" /db_xref="CDD:131916" misc_feature complement(30875..31045) /locus_tag="ClothDRAFT_2021" /note="Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471" /db_xref="CDD:144895" misc_feature complement(30479..30778) /locus_tag="ClothDRAFT_2021" /note="Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486" /db_xref="CDD:148857" gene complement(31467..31841) /locus_tag="ClothDRAFT_2022" CDS complement(31467..31841) /locus_tag="ClothDRAFT_2022" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430161.1" /db_xref="GI:256005193" /translation="MIYKRDPRFRRYGPAAAQNISYMPDSSFASGNAVNPTGDTLREV EKIPLPNEKDETAFDAMPAAGSRSPSMFFRKLHSDEIILLFLIFILIAEGIDDDFLLI VLIYLLVSEIFEEYFRLQNKSV" gene complement(31855..32316) /locus_tag="ClothDRAFT_2023" CDS complement(31855..32316) /locus_tag="ClothDRAFT_2023" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: viral A-type inclusion protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430162.1" /db_xref="GI:256005194" /translation="MSDDLNNKLKQLADMLNGNEKMSENLSSLISMLAKSSGNDKPAQ TSSEEKSPKEEPSMKIKAQDSIKAENLPLQSDTKENERNIDELQDNAEMMRRIKDVMD AMRNINDPRINLLTAIKPFLSSGRQKKLSNCIRLFQVTQITKLMSDPEKTI" gene complement(32391..32714) /locus_tag="ClothDRAFT_2024" CDS complement(32391..32714) /locus_tag="ClothDRAFT_2024" /inference="similar to AA sequence:KEGG:TVAG_420820" /note="KEGG: Beige/BEACH domain containing protein" /codon_start=1 /transl_table=11 /product="Beige/BEACH domain containing protein" /protein_id="ZP_05430163.1" /db_xref="GI:256005195" /translation="MVDINKKLSELFGKMDQKMLEKRINTAIEMLKNGDVDELSKKIN KIDKNELLEKINEFDESKLKEFNINKDEIRQKITDADLSKLSQLLGEHGDEIVEKLKG ILEKP" gene complement(32935..33105) /locus_tag="ClothDRAFT_2025" CDS complement(32935..33105) /locus_tag="ClothDRAFT_2025" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430164.1" /db_xref="GI:256005196" /translation="MSDIKKRTNNSELLFFILIFLLLFYDSSAIGGIKHDVKDDDTIL FFILVFLKLFYC" gene 33357..34025 /locus_tag="ClothDRAFT_2026" CDS 33357..34025 /locus_tag="ClothDRAFT_2026" /inference="protein motif:PFAM:PF02683" /note="PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: glo:Glov_2275 cytochrome c biogenesis protein transmembrane region" /codon_start=1 /transl_table=11 /product="cytochrome c biogenesis protein transmembrane region" /protein_id="ZP_05430165.1" /db_xref="GI:256005197" /db_xref="InterPro:IPR003834" /translation="MDSSVYVTAFAEGILTFVSPCIFPMLPAYFSYLAGFSDKEDKDG KNKRRLLINSLGFVLGFTIVFTLLGAAATSLGAFLKEHRDVLKIISGIVIIIFGLNFI GILNIGFLNREKRFEYKADSLKFVGSVIFGFCFAFGWTPCISYFLASILALAANSSTM PEGLMLLVVYSLGLGIPFIVSAMIFESIREAFNFIKSNMRIINIISGILLILLGAAML FNII" misc_feature 33381..33920 /locus_tag="ClothDRAFT_2026" /note="Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl00515" /db_xref="CDD:153822" gene 34087..34683 /locus_tag="ClothDRAFT_2027" CDS 34087..34683 /locus_tag="ClothDRAFT_2027" /inference="protein motif:PFAM:PF00578" /note="PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thioredoxin domain; Redoxin domain protein; KEGG: gur:Gura_3739 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen" /codon_start=1 /transl_table=11 /product="alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen" /protein_id="ZP_05430166.1" /db_xref="GI:256005198" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR006662" /db_xref="InterPro:IPR013740" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR017937" /translation="MKKTVNIVIWTAVLVFLIIGAYFVYSRNNSAEYIEDKIAEDTNN DKAAGDNGGTKEENKIMAPDFSLKDLDGNTVKLSDYRGKIVFLNFWASWCGPCTSEMP EFEKVHRQFSKEDDAVILAVNLTDGFRETEEKARKFIADNGYTMKVLLDTTGSAAKDY GIYSIPTTYVINRDGSIVTYMEGARPGKVLLDIYEKLK" misc_feature 34276..34635 /locus_tag="ClothDRAFT_2027" /note="TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing...; Region: TlpA_like_family; cd02966" /db_xref="CDD:48515" misc_feature order(34366..34368,34375..34377) /locus_tag="ClothDRAFT_2027" /note="catalytic residues; other site" /db_xref="CDD:48515" gene 34720..36003 /locus_tag="ClothDRAFT_2028" CDS 34720..36003 /locus_tag="ClothDRAFT_2028" /inference="protein motif:PFAM:PF00070" /note="PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Thioredoxin domain; KEGG: pca:Pcar_0114 thioredoxin reductase" /codon_start=1 /transl_table=11 /product="FAD-dependent pyridine nucleotide-disulphide oxidoreductase" /protein_id="ZP_05430167.1" /db_xref="GI:256005199" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR001327" /db_xref="InterPro:IPR013027" /db_xref="InterPro:IPR013766" /translation="MNDAIVKSTMENFDKDVLKSDIPVAVLFYTESCPVCDAFMPIFE RTAQKYGKYMKFVKIYRQQNRQLVEDLKIKSSPTVLFYKEGNEVCTRLNGYISNAEFV EAIERVIGDVCKGEKREKVHCDFLILGGGPAGLTAAIYAARAKLHTVVVDEGLIGGQV ATTFQVANYPGTNGVVRGIDLMENMKKQALDFGAYIDDLKEISDVNLEGKEKLVTAKD TDYYAKAVLIATGATPRRLPAEGEKEFRGRGVHYCATCDGAMYFDANILVVGGGESAA EEAVFLTRYAKHVTIINRHDYLKASKTAQDEVFRNPNISVVWNSEVRKINGDSFVKSV TIENLKTGKIEEIETDGLFVYIGTQPKTELFAGKVGMNEEGYILTNEDMATNIPGVFA AGDVRAKKVRQIATAVGDGAVAGIMAERYINGKFY" misc_feature 34750..35037 /locus_tag="ClothDRAFT_2028" /note="TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947" /db_xref="CDD:48496" misc_feature order(34816..34818,34825..34827) /locus_tag="ClothDRAFT_2028" /note="catalytic residues; other site" /db_xref="CDD:48496" misc_feature 35086..>35235 /locus_tag="ClothDRAFT_2028" /note="Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; cl14644" /db_xref="CDD:187400" misc_feature 35089..35985 /locus_tag="ClothDRAFT_2028" /note="thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292" /db_xref="CDD:162288" misc_feature 35512..35733 /locus_tag="ClothDRAFT_2028" /note="Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; cl14644" /db_xref="CDD:187400" gene 36057..36950 /locus_tag="ClothDRAFT_2029" CDS 36057..36950 /locus_tag="ClothDRAFT_2029" /inference="protein motif:PFAM:PF07992" /note="PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: dde:Dde_2151 thioredoxin reductase, putative" /codon_start=1 /transl_table=11 /product="FAD-dependent pyridine nucleotide-disulphide oxidoreductase" /protein_id="ZP_05430168.1" /db_xref="GI:256005200" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR004792" /db_xref="InterPro:IPR013027" /translation="MYDVIIIGKGPAGISASLYTVRANLKTLVIGKGDSALKKAERIE NYYGFSEAISGERLLAEGEKQAARLGVEIIESEVISIEKNEFFEVLTSDDRYMAKAVL IATGQPQKKLRIENLEAFEGRGVSYCTTCDGFFYNNLKVGVVGAGDYVVHEAMELLAF TKDITIYTNGNELQVSEKFVEAAKRFRISKKPIYKIDGSEFLQKIFFKDGTSEDIDGL FIAYESPSSVDFARKLGIIVEGNAIVVDKNQQTNLEGLFAAGDCTGGFKQIATAVGQG ALAGRKMIEYVRSLETANSPV" misc_feature 36060..36917 /locus_tag="ClothDRAFT_2029" /note="thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292" /db_xref="CDD:162288" misc_feature 36060..>36167 /locus_tag="ClothDRAFT_2029" /note="Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl10040" /db_xref="CDD:186896" gene 37221..37769 /locus_tag="ClothDRAFT_2030" CDS 37221..37769 /locus_tag="ClothDRAFT_2030" /inference="protein motif:PFAM:PF04308" /note="PFAM: protein of unknown function DUF458" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF458" /protein_id="ZP_05430169.1" /db_xref="GI:256005201" /db_xref="InterPro:IPR007405" /translation="MLPNVAVEFDENSIFRSLGKGNLTFREAFEEIIKFIEADTNSSY RISIGTDSHVGNGTLFVTCIHVHRIGKGAIGFLHKSLMSRPIRNLREKIYMETCMSLQ LAYLFDEEKIDRIYKALGKNGKSPTKGVTFEFHIDIGKRGETKALINEMVGMVSGLNF IPKIKPDSYCASCFADRYTKAI" misc_feature 37335..37760 /locus_tag="ClothDRAFT_2030" /note="Protein of unknown function (DUF458); Region: DUF458; cl00861" /db_xref="CDD:120183" gene 38064..38747 /locus_tag="ClothDRAFT_2031" CDS 38064..38747 /locus_tag="ClothDRAFT_2031" /EC_number="4.1.2.4" /inference="protein motif:TFAM:TIGR00126" /note="KEGG: bba:Bd3854 hypothetical protein; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase" /codon_start=1 /transl_table=11 /product="deoxyribose-phosphate aldolase" /protein_id="ZP_05430170.1" /db_xref="GI:256005202" /db_xref="InterPro:IPR002915" /db_xref="InterPro:IPR011343" /translation="MRKDESILDKNTVISMIDHAVLKPEATDNDVLRECEIAARYGVA SVCVKPCHVALAREALKDSKVKVSTVIGFPHGSTTTACKVFEAVEAMENGAEELDMVI NIGKLLTGDYDYVREDIKRVVSVAHERGVIVKVIIETALLDLNHKVQACKLAEEAGAD FVKTSTGFAGKGATLEDICIMRGAVGPNMKLKASGGIKTFEQAAEFVNAGCERLGTSS TAAIAEEIG" misc_feature 38100..38714 /locus_tag="ClothDRAFT_2031" /note="2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family. DERA belongs to the class I aldolases and catalyzes a reversible aldol reaction between acetaldehyde and glyceraldehyde 3-phosphate to generate 2-deoxyribose 5-phosphate. DERA is unique in...; Region: DeoC; cd00959" /db_xref="CDD:29952" misc_feature order(38127..38129,38133..38135,38139..38141,38211..38219, 38280..38282,38304..38306,38319..38321,38334..38345, 38370..38372,38376..38378,38433..38438,38484..38486) /locus_tag="ClothDRAFT_2031" /note="intersubunit interface; other site" /db_xref="CDD:29952" misc_feature order(38550..38552,38559..38561,38643..38651,38706..38714) /locus_tag="ClothDRAFT_2031" /note="active site" /db_xref="CDD:29952" misc_feature 38550..38552 /locus_tag="ClothDRAFT_2031" /note="catalytic residue; other site" /db_xref="CDD:29952" gene 38838..39737 /locus_tag="ClothDRAFT_2032" CDS 38838..39737 /locus_tag="ClothDRAFT_2032" /inference="ab initio prediction:Prodigal:1.4" /note="KEGG: gsu:GSU2922 hypothetical protein" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430171.1" /db_xref="GI:256005203" /translation="MRRLLCVITVCIMILSFCAGCLDNDRFGLGDNEEASVASSIVLS EADARQIADKSPIRLYFANEDNSKLKLEIRYIPVSETTKSVNHLAEIIVNELIKGPKV AGLKPTIPEGTKLRSAIKIEGDVAIVDFTKEFRDNHPGGKAEERMTIYSVVNSLTELK EINKVKFLIEGKSSPDFKGNFRFNTEFPRSTQLISNKAEPVGTVNSKDAADKKDDSAS GDKDTADVSNETENESVETGAQTSDDEEVFVDDSLDGEAQETYQETNDDEKWQETYDE ASDEEARQTFSDEFEETYIEYLE" sig_peptide 38838..38900 /locus_tag="ClothDRAFT_2032" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.628) with cleavage site probability 0.468 at residue 21" misc_feature 39012..39368 /locus_tag="ClothDRAFT_2032" /note="Sporulation and spore germination; Region: Germane; pfam10646" /db_xref="CDD:151159" gene complement(39776..39991) /locus_tag="ClothDRAFT_2033" CDS complement(39776..39991) /locus_tag="ClothDRAFT_2033" /inference="protein motif:TFAM:TIGR02605" /note="TIGRFAM: regulatory protein, FmdB family; KEGG: dat:HRM2_02720 hypothetical protein" /codon_start=1 /transl_table=11 /product="regulatory protein, FmdB family" /protein_id="ZP_05430172.1" /db_xref="GI:256005204" /db_xref="InterPro:IPR013429" /translation="MPFYDLKCSKCGHEFNVMAKMSERTEKLIKCPECGSNELDAVFK SVNIIQSRKSEGGECPNIHKCGGCCSH" misc_feature complement(39863..39991) /locus_tag="ClothDRAFT_2033" /note="Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993" /db_xref="CDD:163941" gene 40173..40913 /locus_tag="ClothDRAFT_2034" CDS 40173..40913 /locus_tag="ClothDRAFT_2034" /inference="protein motif:PFAM:PF06271" /note="PFAM: RDD domain containing protein; KEGG: tcx:Tcr_1706 RDD" /codon_start=1 /transl_table=11 /product="RDD domain containing protein" /protein_id="ZP_05430173.1" /db_xref="GI:256005205" /db_xref="InterPro:IPR010432" /translation="MTVSGVLRRYFAWLIDSIILAGLTFGLTMFLEALGVGVPLNELV QAMIRKTEQSLEVINSFQLEVWAIYAVLFFIYEIVFVASSLSATPGKIILGIEIVSDR KSSIDKVIIRALVKFIGEMFPFSLVNFIIVLVSGKKQSLHDKAARTYVVYKKVENNYS KKIDPKELFEEMKRRGLRTYSEQLALAEELYGKNRKKARTSASYGWISLVLLIVGLVL FGVFFSRYLSIYREIYTDAFIRDYIHYN" misc_feature 40179..40613 /locus_tag="ClothDRAFT_2034" /note="RDD family; Region: RDD; cl00746" /db_xref="CDD:153968" gene 40977..41114 /locus_tag="ClothDRAFT_2035" CDS 40977..41114 /locus_tag="ClothDRAFT_2035" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430174.1" /db_xref="GI:256005206" /translation="MDSGPLPCCGNKKYHNMFGAIATVGVVCGSVKGGLHNERNDSGA H" gene 41086..42420 /locus_tag="ClothDRAFT_2036" CDS 41086..42420 /locus_tag="ClothDRAFT_2036" /inference="protein motif:TFAM:TIGR00400" /note="KEGG: tdn:Suden_1342 divalent cation transporter; TIGRFAM: magnesium transporter; PFAM: MgtE integral membrane region; MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein" /codon_start=1 /transl_table=11 /product="magnesium transporter" /protein_id="ZP_05430175.1" /db_xref="GI:256005207" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR006667" /db_xref="InterPro:IPR006668" /db_xref="InterPro:IPR006669" /translation="MKEMILELIEQGKYAEVRNKITEMNEVDIAQLLEETDKHKLLVI FRILPKDVAAGVFSYISYELQRYIVESITDSEIKNILDELFLDDTIDFLEEMPSNIVK RVLKNADETTRKLINQFLNYPENSAGSIMTIEYVDLKKEMTVKQALQHIKETGIDKET IDTCYILDDSRKLEGVISIRKLILSDESVVIKDIMDADVIYVNTHDKQEEIAALFKKY DFLSMPVVDNERRLVGIVTIDDIVDVIEQENTEDFQKMAAIQPSEKEYLKTNALVLAK HRITWLLVLMLSATFTGNIIKKFDEVLQSIVILASFIPMLMNTGGNAGSQSSALIIRG LSLGEIRARDFLKVLWKEIQVSCIVGVVLAAVNFVRIYYFEKAGFLVSATVCLTLFFT IMLAKVIGGLLPIMAKKLKLDPAIMAGPLITTVVDAVTLTIYFTIATWLLDI" misc_feature 41098..42417 /locus_tag="ClothDRAFT_2036" /note="Mg2+ transporter (mgtE); Region: mgtE; TIGR00400" /db_xref="CDD:129495" misc_feature 41155..41460 /locus_tag="ClothDRAFT_2036" /note="MgtE intracellular N domain; Region: MgtE_N; pfam03448" /db_xref="CDD:146204" misc_feature 41497..41781 /locus_tag="ClothDRAFT_2036" /note="This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE. MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606" /db_xref="CDD:73106" misc_feature 42019..42399 /locus_tag="ClothDRAFT_2036" /note="Divalent cation transporter; Region: MgtE; cl00786" /db_xref="CDD:120115" gene 42945..44075 /locus_tag="ClothDRAFT_2037" CDS 42945..44075 /locus_tag="ClothDRAFT_2037" /EC_number="6.3.2.4" /inference="protein motif:TFAM:TIGR01205" /note="KEGG: cvi:CV_2472 D-alanyl-alanine synthetase A; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; RimK domain protein ATP-grasp" /codon_start=1 /transl_table=11 /product="D-alanine/D-alanine ligase" /protein_id="ZP_05430176.1" /db_xref="GI:256005208" /db_xref="InterPro:IPR000115" /db_xref="InterPro:IPR000291" /db_xref="InterPro:IPR003135" /db_xref="InterPro:IPR003806" /db_xref="InterPro:IPR005905" /db_xref="InterPro:IPR011095" /db_xref="InterPro:IPR011127" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013651" /translation="MGDKKRVLVIFGGQSSEHEVSRISATSILKNINLDKFDVSMIGI TKDGKWLYYDGPIDKIPSGEWEEIALKDGTRSIADRVSLFDNIISCKNNACGLEKASE NEKSKKIDVVFPVLHGCNGEDGTIQGLFELAGIPYVGCGVLASAVGMDKIYAKIIFEK AGIPQADYLYFTRKEIYGDVEGVVDKIEEKFSYPVFVKPSNAGSSVGVSKAHDKNELK EALIYAARYDRKVLIEEFINGREVECAVLGNDDPVASTVGEIIPGNEFYDYKAKYIDN TSKIKIPADLPEETVEQIRNYAVKAFKALDCSGLARVDFFVHKETGKVYINEINTMPG FTSISMYPMLWEESGISYPELIEKLIDLAVQRYNDNLKEYDE" misc_feature 42954..44033 /locus_tag="ClothDRAFT_2037" /note="D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966" /db_xref="CDD:179356" misc_feature 42957..43364 /locus_tag="ClothDRAFT_2037" /note="D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820" /db_xref="CDD:145141" misc_feature 43413..44027 /locus_tag="ClothDRAFT_2037" /note="Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; cl03087" /db_xref="CDD:164032" gene 44140..44946 /locus_tag="ClothDRAFT_2038" CDS 44140..44946 /locus_tag="ClothDRAFT_2038" /EC_number="5.1.1.3" /inference="protein motif:TFAM:TIGR00067" /note="KEGG: geo:Geob_1363 glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/hydantoin racemase" /codon_start=1 /transl_table=11 /product="glutamate racemase" /protein_id="ZP_05430177.1" /db_xref="GI:256005209" /db_xref="InterPro:IPR001920" /db_xref="InterPro:IPR004391" /db_xref="InterPro:IPR015942" /translation="MDNRPIGVFDSGLGGLTVLKEIKNLLPRESIVYFGDSGRAPYGS KSKETVVKYTFQDIRFLLNQDIKMIVIACNTASACSLDQVKNSFDIPIVEVVGPGAAT AVRETVNKKVGVIGTVATVSSGVYEKAILKLDPEIEIYQKACPLFVPLVEEGWWENDI ALRIAEEYLLPLKEKNIDTLVLGCTHYPLLYNTISKVMGDGVKLVSSALEVAKVVKEM IEKSNLNRDEKLNPVYRYYTSDSVYKFESLGNSILNHEICSAEKVDIERY" misc_feature 44140..44901 /locus_tag="ClothDRAFT_2038" /note="Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518" /db_xref="CDD:186052" gene 45005..45472 /locus_tag="ClothDRAFT_2039" CDS 45005..45472 /locus_tag="ClothDRAFT_2039" /inference="protein motif:PFAM:PF09148" /note="PFAM: Domain of unknown function DUF1934" /codon_start=1 /transl_table=11 /product="protein of unknown function DUF1934" /protein_id="ZP_05430178.1" /db_xref="GI:256005210" /db_xref="InterPro:IPR015231" /translation="MNKNVIISVKGVQTSENNDKNVLELVTEGKYYKKGNAYYVTYKE SEVTGMEGTTTTLKISDGVVTLMRFGTVNAQFIFEEGQKHVSYYDTQYGTFTMKVTAR SVLINVDDSGGEIKVDYKLEIDDNKSGENDFHMFIREVGQLDDECSGDYKKTN" misc_feature 45023..45409 /locus_tag="ClothDRAFT_2039" /note="Domain of unknown function (DUF1934); Region: DUF1934; cl01870" /db_xref="CDD:154634" gene 45435..47129 /locus_tag="ClothDRAFT_2040" CDS 45435..47129 /locus_tag="ClothDRAFT_2040" /EC_number="6.1.1.19" /inference="protein motif:TFAM:TIGR00456" /note="KEGG: pca:Pcar_0742 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase" /codon_start=1 /transl_table=11 /product="arginyl-tRNA synthetase" /protein_id="ZP_05430179.1" /db_xref="GI:256005211" /db_xref="InterPro:IPR001278" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR005148" /db_xref="InterPro:IPR008909" /db_xref="InterPro:IPR015945" /translation="MTNVVETIKKQINEVVKNSISKAVQNGELPQFTVDELFIEIPKE KGHGDFSTNIAMQAAKTVRKAPRQVAEIIIKNMDLSNTYIDRVEAAGPGFINFFLTNA WLYDVLKVIQKEKENYGNLDIGRGQKVMVEFVSANPTGPLHMGNARGGALGDCIASVL EKAGYDVTREFYINDAGNQIEKFGISLEARYIQLLKGEDAVEFPEDGYHGEDIIDHMK AYIEENGDNLLYVDSEERRKTLVEYALPKNIERIRKSLENYGVVFDVWFSEQSLYDNG EVRETLDILKEKGYTFEKDGAVWFKASALGAEKDEVIVRNNGIPTYFAADIAYHRNKF LKRKFDRVINLLGADHHGHAARMKCALKAFDIDPDKLDIVIFQLVRLYRNGEIARMSK RTGRAISLDDLLEEVGRDAARFFFNTKASGSHLDFDLDLAVKKSNENPVYYVQYAYAR SCSMLRLLESEGFKVPDVDSVDLTVLKAPEEIELMKKLSEYPEEIRISAQTLEPSRLT RYVLDVASNFHSFYNACRVKGEEENLMYARMILVDSTRLVIKNVLDVLSITAPEKM" misc_feature 45456..47126 /locus_tag="ClothDRAFT_2040" /note="arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611" /db_xref="CDD:179308" misc_feature 45462..45731 /locus_tag="ClothDRAFT_2040" /note="Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485" /db_xref="CDD:146238" misc_feature 45816..46619 /locus_tag="ClothDRAFT_2040" /note="catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671" /db_xref="CDD:185675" misc_feature order(45828..45830,45837..45839,45843..45845,45861..45863, 45870..45872,46398..46400,46410..46412,46482..46484, 46491..46493) /locus_tag="ClothDRAFT_2040" /note="active site" /db_xref="CDD:185675" misc_feature 45861..45872 /locus_tag="ClothDRAFT_2040" /note="HIGH motif; other site" /db_xref="CDD:185675" misc_feature 46602..46613 /locus_tag="ClothDRAFT_2040" /note="KMSK motif region; other site" /db_xref="CDD:185675" misc_feature 46647..47126 /locus_tag="ClothDRAFT_2040" /note="Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020" /db_xref="CDD:159680" misc_feature order(46722..46724,46734..46736,46743..46745,46770..46772, 46782..46787,46791..46796,46959..46961,46980..46982, 46989..46991,46998..47000) /locus_tag="ClothDRAFT_2040" /note="tRNA binding surface; other site" /db_xref="CDD:153408" misc_feature order(46770..46772,46779..46784,46791..46796,46998..47000) /locus_tag="ClothDRAFT_2040" /note="anticodon binding site; other site" /db_xref="CDD:153408" gene 47311..47988 /locus_tag="ClothDRAFT_2041" CDS 47311..47988 /locus_tag="ClothDRAFT_2041" /inference="protein motif:PFAM:PF02517" /note="PFAM: Abortive infection protein; KEGG: saz:Sama_2782 hypothetical protein" /codon_start=1 /transl_table=11 /product="Abortive infection protein" /protein_id="ZP_05430180.1" /db_xref="GI:256005212" /db_xref="InterPro:IPR003675" /translation="MVDSKNKKYIIKVLIPYLIVFYFFWSVYTIFLEPFIEKGPYLLN LLLVNFVKLCFWTVPALVVLKYVFREKPLSYIKLSKDKLRGFAYGSLYGVVIVIYISV TRFLFSGEFNFNPFFGLESWIGGVLLIGFTEEIVFRGFLLQKFEEIMDSKYANLLTAV LFLLIHFPKWYMQGNLFVAEFMVNSVLFMLLFSVLMAVLLKKTNSLWTCILIHSANNF AMFALGE" misc_feature 47674..47982 /locus_tag="ClothDRAFT_2041" /note="CAAX amino terminal protease family; Region: Abi; cl00558" /db_xref="CDD:163875" gene 48076..48711 /locus_tag="ClothDRAFT_2042" CDS 48076..48711 /locus_tag="ClothDRAFT_2042" /inference="protein motif:COG:COG2220" /note="KEGG: xau:Xaut_0496 hypothetical protein" /codon_start=1 /transl_table=11 /product="Zn-dependent hydrolase of the beta-lactamase fold-like protein" /protein_id="ZP_05430181.1" /db_xref="GI:256005213" /translation="MKIKWLGHACFLLTSDNGIRVVTDPYDNTVGYKVEKIDAEIVST SHDHYDHNYVDMVSENAKHVKSEGKTNIDGIEITGVTSFHDDCKGAKRGKNVIFKFKI DGIDVCHLGDLGHVLSDSQVREIGNVDVLLVPVGGVYTIDYKGAVEVMKLVNPKITIP MHYKTPALSFDVDGVENFLSATGGKHIGKQEIELKKDEIENWPKVVALDYQ" misc_feature 48076..48630 /locus_tag="ClothDRAFT_2042" /note="Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446" /db_xref="CDD:186000" gene 48913..51918 /locus_tag="ClothDRAFT_2043" CDS 48913..51918 /locus_tag="ClothDRAFT_2043" /inference="protein motif:PFAM:PF00395" /note="PFAM: S-layer domain protein" /codon_start=1 /transl_table=11 /product="S-layer domain protein" /protein_id="ZP_05430182.1" /db_xref="GI:256005214" /db_xref="InterPro:IPR001119" /translation="MEKKFSNKPGIRICFVMVFSFVLSFALNIPVHADEEPEKIYYGL KNASTILNNINFTDVRNSATWSKEAICEAAALDIVKGYGNRVFGRTNNVTKEEAIAII YRAAGREKDAQLAAEALETARNAEDRSSYAPSMWSDGYLQLAAGEGLISSQDLQDAFT ADQSSLGTGAFLRRAPAQRQEVAYWISKVFDIEPVYGQQKIFNSFRDWSSADPLKIPY IEAVLVENIMNGEGNGYFRPTGFVTREQIAQIIKNADKRVLPLLGYEKKMGTVEDIRK EYDFTGNTHVYTNTFHIRSSNGKLHKIVTEFYDSSRSGYRNEQGGSSIKPSDTDLIVY RDGWIGTSSLLKVGDRVEYITAADGTVRYVRVISATSDTEYIVAKIKEVNYDTSTIKA AIGFYLEYPDIDMDSISFDFRNSDGTVDATLVYSNIVKVFIEGRIAGIRDIEPGTDAI LTVKDNIITTITTLDLRLKEQGVISGIVEENNPHLGYISLYSDNGLRVDDSLNKIKIY NYSNPEEVTVYKNHVPAKLEDVESGDSVYIKLDQNGAIEMISAVDNYVVKYGKIISVR PGLINVAYDDGTQQILSVDENVPIVQDNKLMDFDALKDGDRVKLLLNITDKATTLKKL TVEGDEHFIANIYRGIVASVDDISKKLLLQHLEVFNNGEWERTEQKGFTSLKMSEDNK FVYNDDIVDMRRAKELIAGSTAYIAVEKDYGGIEKAVFVSVKNSKDSEAPVLNDSIMS ATFGNKGEFTLKKEYLNISYGNGTIIVKDNRLVTGNSINSEDRAYVVASRSYDDGKYY AFIVKIDDKTDSNFFTIYRGRIANINENKDFTLESYSELKGVEWNYYNTPRTFRITYD TQILGDDGVVGQRDFTDYGDSSYKSRTVYVLSHGADAVLISTAPYGNINVKGKIYELI SENADGSEAQEGQQEPVGFKLQNSKVYDLQSHMWVDGKDMDINLLKNSIILKDNKIIK PSELKKGDSVRLIKKDDEQAGDAYIIFVE" sig_peptide 48913..49014 /locus_tag="ClothDRAFT_2043" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 34" misc_feature 49075..49209 /locus_tag="ClothDRAFT_2043" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature 49522..49656 /locus_tag="ClothDRAFT_2043" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" gene 51946..53511 /locus_tag="ClothDRAFT_2044" CDS 51946..53511 /locus_tag="ClothDRAFT_2044" /inference="protein motif:PFAM:PF00395" /note="PFAM: S-layer domain protein; KEGG: hypothetical protein" /codon_start=1 /transl_table=11 /product="S-layer domain protein" /protein_id="ZP_05430183.1" /db_xref="GI:256005215" /db_xref="InterPro:IPR001119" /translation="MIKRKLSLKRGLAFITATFIIVLVTGVFRVYAREGDSGYEGGIS SGEAPGKTSFEYKEVCFITGEPIVFEGTLTIRKTLRQDKTTGKNVITANYTYNLRNLE KDATLTRVLSYTTTLTEKENGQVIEETGFGGRCTEVVRIGSTTYTLENYDFTKTNIKD KKPAVDYFAGNLWGKKTYRTGTGANSGEVTVEISGDYYGYNQIWGTVEAQVLNYVIES QKRSGEVLDRWGGTATVSISSTTTKKIDYVENKPDVISFEGGFVESQYNNSILQYTAK LPEFDHQGVSTDRMVETKGSLMIESFPTSRRLLVPELSHLRGHWAENDIKALYSLEIF KENPSGFNPQEVMTRAEFTEAIVLAAGEVPKDPLLVESRTTKKTSNTKEEITSPFIDV PTGSKYFESINNAYKRGMISGRGDGTFAPDDYLTTADAITILVKALGLEGLAPSNGAV TVFRDSDDIPRYAKGPVYVAHRIGLVMGDDKGYLRPNEYLTKARAAVIINNFIDYMRN DLRKDYRERIVNY" sig_peptide 51946..52044 /locus_tag="ClothDRAFT_2044" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.993 at residue 33" misc_feature 52897..53001 /locus_tag="ClothDRAFT_2044" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature 53107..53238 /locus_tag="ClothDRAFT_2044" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" gene 53585..55102 /locus_tag="ClothDRAFT_2045" CDS 53585..55102 /locus_tag="ClothDRAFT_2045" /EC_number="3.4.21.102" /inference="protein motif:TFAM:TIGR00225" /note="KEGG: sfu:Sfum_3063 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; Peptidoglycan-binding domain 1 protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein" /codon_start=1 /transl_table=11 /product="carboxyl-terminal protease" /protein_id="ZP_05430184.1" /db_xref="GI:256005216" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR004447" /db_xref="InterPro:IPR005151" /translation="MDVTGKSLKRILLSLAVFCILITGPGIACAEEATTQEKEILFSD YFKSMMDMAQDKYKGEITEKQMLEGALKGIFSTMDSYTVYYTVEESQDFFTDINGSYT GIGVVMSEVDGKIVIDKVYPSSPAEEAGIKKGDVIAQVDGKSVENLSLEEVAGLIKGP SGTKVVIGVLRNGTDGVIELEVTRRQIIINPVTHKIEGDIGYIKLESFNSNASKAMEE ALKQMDKNNIKKIILDLRDNPGGDVGQAVSIARKFVKKGLITKLDFKSESQKDEEYYS YLEELKYKLVVLVNENSASASEILAGAIQDTGSGILVGTTTFGKGKVQNLYPILTPEA VEKYRKETGETFVNGYDLLEKHGIYPSDEEIIGWVKITTGEYYTPNGRMIDGVGLEPD VYVENEPEGKYKILEGVEKLRKVTKPSLNAQSEDVLNAEKILSALGYDVDTPDNLMDE KTVKAVAEFQRDCGLYSYGVLDFATQQALNDKLDELLLVKNRDKQYEKAVELLEN" sig_peptide 53585..53677 /locus_tag="ClothDRAFT_2045" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 at residue 31" misc_feature 53714..>53842 /locus_tag="ClothDRAFT_2045" /note="C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526" /db_xref="CDD:154960" misc_feature 53744..54772 /locus_tag="ClothDRAFT_2045" /note="C-terminal peptidase (prc); Region: prc; TIGR00225" /db_xref="CDD:161775" misc_feature 53885..54142 /locus_tag="ClothDRAFT_2045" /note="PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988" /db_xref="CDD:29045" misc_feature order(53891..53902,53906..53908,54041..54046,54053..54058) /locus_tag="ClothDRAFT_2045" /note="protein binding site; other site" /db_xref="CDD:29045" misc_feature <54182..54772 /locus_tag="ClothDRAFT_2045" /note="C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560" /db_xref="CDD:143476" misc_feature order(54467..54469,54542..54544) /locus_tag="ClothDRAFT_2045" /note="Catalytic dyad; other site" /db_xref="CDD:143476" misc_feature 54851..55021 /locus_tag="ClothDRAFT_2045" /note="Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471" /db_xref="CDD:144895" ORIGIN 1 ggactttgtt gaagcgggaa aactgcaggt aggagataag ctgcttgatt caaaaggcaa 61 tgttttggtg gtggaggata aaaagcttga gattacagat gagcctgtca aggtttataa 121 cttcaaggta gatgattttc atacttatca tgttggcaat aatggaatat tggtgcataa 181 tgcaaataat ttatcttaaa gatccaaata agttgttaga gaatggatgg gaagatgtga 241 ctcctgaatg cataagaaaa aatacaaatt caagaatatt atattatgat ccgaaaacag 301 ggacaaaagt aagatttgat ctgaaagcag aagaggtccc cggatacaat ggaaaggatc 361 attatcatat ttataatccc gattttactc tggtaaacat gattattacc ttgacattga 421 cgtgaatccg gttccaaaag gttctaaagc gtctcatata ttaccacagg aagggtggaa 481 ataatgttaa aatataattt tcacgatagt ttgattgaag atgtgaatta tatacctaat 541 gaagccaaat tggaaataaa aattaaattg tgcaactgga tgcaaagtga ttataaagat 601 tccgatccag aaatgcttac tatgcacatg atatttgatg gggttgaaaa attcgaaatg 661 agtactgaaa actatgtgtt taacagtaat gaaattcttg acgttattga attagatgat 721 cggactgtaa aaattatttt tttaacggaa aatgatgtta aaacaattat cgttacagcc 781 gaaagagtgg actatgcaat atacgaaaat gaacaaagtt gaaacatatg tgatgctttt 841 gttttctttg gacgacggtt tgccgagtac accgacttca tcagaatagg gataaacgga 901 aaacttctaa aatacagtaa ataaaaatat atttggtatg tgcgaaggaa aatattataa 961 aacttttaat attatgccag taaaatttaa aagacaaata gaaatacgat ttttatattt 1021 tgaaaatgtt gaaaattaat ctgcttatca ttttttattt attataccct aaattatacc 1081 ctaaattata ccctgcctga tataaatggt gtattaaata atttaaacat ttcaggaaat 1141 ttttaaataa aaatattttt ttggaatgga gtttactatt tttaggaggg aaagttcttg 1201 atttgttgtc ataaaatata atataatatt ggtaagtata ggcaaagtaa gattttaatg 1261 aattgcttta taatattttg tttttatgaa ttgtttgttg aatggagaaa gattttttat 1321 gttttaggga gggatagcgg tggactacag ctatctttat cagagagcga aaagcagata 1381 ttacgaggct tgtgcggaaa ttaccagttg tcagaataaa atagatgatt taaaaaagca 1441 acaacagcaa aaaatcaatc ttatcaatca gttgaaaact gatattaaaa accatgagga 1501 agcgcttgat aaagtaaagg agataattaa aagcgaaggc aattttgaga ataaaatttc 1561 agatatttcc aacaaaacca atgaggcggc aattaattac agcagtatgg ttagttgcag 1621 taatgtagtg aacaaaaatt taaatgaagt ttacggcgat gaaatgagaa atacaaagaa 1681 gacaataaat gacatattta caaattttaa aacaagaaaa aatgagttgg aaactaaaat 1741 tgcagatttg aaaaggcaat tgcagcaagc tgaaaacgat ttggacgaga taaaaaggaa 1801 tataacttta acagaaaacc gtctgcagga ttggaagagg gctaaaacgc aagcttcata 1861 tgatatggaa tattacagac ggaaaatgaa tcaggcagtt taactcataa aaaaatatgc 1921 caagatggca gccgtagcat tatagaggac aaaattgatt gaatatctgg tggttaaaaa 1981 aatattaaaa aatctgtaaa aaaaccatca caattcattt aatgagttta aacgtgcaag 2041 ggaagaacct tatggaggta acttatgaat ataaatgtaa aagatataat agctgattcg 2101 catctggctt ttctaaacca ggaaaacgaa acggctttaa ggctggccag acaggcaata 2161 tccctggcgc cggacaatcc tgacgcatac agatgcgccg gaaacgcttg catgtcattg 2221 gaccgttatg atgaggccat tgagtattac aggacagctg tcaaatatga tcctgacaac 2281 ggcaacaggt attatgacct tggatttgcg ttagcttccg ctgaaagatt ttccgatgcc 2341 ctgaaaaatc ttgcgaaggc agaagagtta ggatgtactc cggaaaatct tgttcagctt 2401 tacaacttgc ttggaatcct ttgctttgat attggaaggt acgatgatgc tcttgtaaat 2461 ttaaacaaag cggaaaagct tatcggtatc gatgttgaca ttcttaagcg caaagctgtt 2521 atatacggta tcaaaaacga tattaagaat ggactgatga cggcaaatca aatcaaactg 2581 gttactccat ctgaatatac cggctatcag attgcattta agttgttggt tcaggcaaag 2641 cgtctggatg aagctgagaa agagttggaa agagccagaa aatatgcatc accgacgatg 2701 gatttctatt ttgactacat gactcttgag cttgaaaagt ataagacaga caatgacaaa 2761 gaacatttta aaactgccct tggaatgatt gaaaaggctt taaaaacggt gaaacctacg 2821 gtgaaagaag tggttgaaag ttacataaac gcagctgaga tatatcttca gcttgaagac 2881 gccgacagag ccattgagtg ccttaatgct gcccaaaatc ccatctgggc ttataacaac 2941 gggtttgacg tggttgtaag gaactatgag cctgttactt tgacggaata tgacatcgaa 3001 gatatgattg aggctgacag gaaaaagata gaggaacagt ttggagatta tggatttgag 3061 gaaatggttg agagtatcga acctgatgag gaaggcaaca gggattattt aactgtaatc 3121 gaagatgaag tgaaaagtga tgcaaaggaa gactcagaag tatataaact tgatgagtcc 3181 gaaaaggttg aatattcttc tgataatata gatcagataa acaggcttta tgtaggagcg 3241 tacacagtaa agaaagattt tgaaaaagtt attgaatatt ccagaaaatt acaagcaagt 3301 gaaaacacat atagtgttta cctgggcaaa tatactgaag cgaatgctat gaaggaactt 3361 ggtttaccgg actttgcggc aaaatatgaa gaaataatca aatttttcag aaatgctatg 3421 attaaagacc ctacggatct gactgctgtt actttcagag tccagtgcta cattgacatt 3481 gggcagtatg atgaggccga acagctttgc agccttttga cgaaggaagt gagaaattca 3541 tttatggaaa agattaaaaa agcgaagtcc ggaggtgagc agcattgaag ttaaagcaag 3601 atatagtcct tgatgatatg gctttccata ctgcatcagc tgagatgaaa gctctaaaag 3661 aaaggactga ggcactcaga actaagcttg aggagatgta caaagatctg acgacagcat 3721 tggacactcc cgccggcagg caagttaaaa taacggcgga agaagttttg ctcaaaccaa 3781 ttgatgattt tttgcttgta attcagcatg tttccgatac tctcgctgag ataatcggaa 3841 caggctatta taaagatatt tttatcaagt ttgaacagct taatgaaagc ataaaatttg 3901 attaatttta atttaaggag gggtatttta tggcaatggg aagtacaggt actatacata 3961 tgacaccgga aatgttgcaa aatgccatgc aggctattga agattacaaa gctaccacag 4021 acaaccttaa gacacagttg gataatacaa ttaacacgtt gctttcctca agtttcagcg 4081 gtaatgcggc ggaaggtttc aaatttttct atgataatac catcagacct gctattgaag 4141 aaggattgag cagtttgctg actacgttga atgatattat ggatggaata ttaaaagcaa 4201 tacccggtga aaacggtttg gacgatcaac ttggagagca aaacagacaa caaggataaa 4261 aaaggaggaa tgaataatgg ccggttgcag gatagtaaac caaggcatgc ttgatgcgat 4321 aagtgaaatt caaagaattg cgggtgaata cgaaacggtg gctgatgagt ttatttcaag 4381 tttaaataat gccattagcg agatggaagg tgaaacaaaa gacgcacttt atgaattaat 4441 taattcgaag gtaaaaacat ttgtatatca ggatttaccg gctgcgctca gaggtatggc 4501 cgagttgctt gaagccaaca gacaaaactt tgaaaacact gataaacaat tggcgggaag 4561 cataagcagc agcgagggct gattatgcgc agttaaattt gattgtacag cgtggaaatt 4621 ggattggccc taaccatcac tgagagtgtg gttagggcta taatgggatt tttttatatg 4681 aagggagacg gttcgttatg gcgttcagaa tacttagcga agaggaagta tccttgcttg 4741 acgaggagca gagaaaacag tatgaaaaag aacttagaat ataccgacaa agagctgctt 4801 ttgttgagca aatcgaggct tatgaaaagg tccgtatccc gccatatgaa cctgacttaa 4861 aaccaattac agtgatgaaa aaatttgaag ttaaacctta tacaagacca gaatatacag 4921 tagcagaata taagccagta gaaaagccgg aattgccaat taagccgttt aaaccggcag 4981 aaacgggaaa ccctgtgttg cctgagattt caaagccggt gagtaccgat atcagccctg 5041 taaaaaaagt ggagaatgtt gaaactgaac tacagactgt tgataaaccg gttattccca 5101 agttacggtt tgaaaagttg gaaggggaat atcctgattt gcctgtgatt ccgaagataa 5161 acgtggtgaa caaatcctat aaaggtacac gggaagtcaa ggtgaattta ccggaagttg 5221 tcaaaccgga aattcaggca ggtttttcgt ttaaaacacc aggttttgat tcttctggca 5281 taaaagcaag cataccggag atttctgtgt ctggtgtaag tttaaagcct tttgttacgc 5341 cggaaaaatc tttgtctgat ttgccgcagg taaaggtttg tcatgcacag gtaaaggctt 5401 tcagaaatcc cgaacagacc ggtactgtgt tgccgcaggt aaccagaccc tatattgatg 5461 ttaattatgt taaaaatgaa aagtctgttc ggctgagttt gcctgaactg cgcaatatat 5521 caaaagtcag tatggtattt aaaaaacctg aaaaatcaga agcaggaata ccatcgtttg 5581 taaagccgaa agtcagaatt gccgcattca gaaaaacaga attaaacagg gtggatttgc 5641 ctgagaaata cagaattgat atcaaaagga cagtattttc aaaacctgaa attcagtttt 5701 cagctttacc tcaggttgca aaattggaat acaaagtaca aagctttaaa agagcggaac 5761 ttcaggttcc ggttttatcg ccggtttcaa aagttggcag tgacataaga accttcaaaa 5821 aaccagagta taagaatttt gttttgcctg tgattccaaa aataagtatt gtaacagaga 5881 atttcaagca agtgaaggta acgcagccac atgttgctct tggcccagat actgtggtgt 5941 caccaagtat taaactcaaa ccgtttgaaa aagttgaaaa caaggctgtc ggtctgcccg 6001 agggaattac cgtaaatatt cctgacgtgt cagaggaatt ggaacaattg ttgcagtcaa 6061 aaaagaatga taagtaagga gctctgaaag gaatagacct atgaaaaaca atgagattat 6121 gatttctgta aagtttgaga gtgacgattt ttccgatgag ttgtctttcc ttgttataaa 6181 agatatttct cttaaagcgc ttattgaagc aatatattat ggattaaaaa aagcaaaggg 6241 ttatgagaaa cattttaatc tggttgacaa atatttaaaa acccgtaaag aattgcaagt 6301 attgtacaat gcaaaaggag attttaacgt tattgatttt acggaagagg ttgacggaac 6361 taaaatattt aataaaaaat tggatgaatt aggctttgta acatcaagct gtattttatt 6421 tacaactgat acgaaagttg caccaaaacc attattccag aaaaatgaaa gaagttatat 6481 attaaaatcc ggaaattccc tggaatacaa tataagtaca agacgtttaa atgtcattga 6541 gccatcggtg attgagatta ttccaccggg tgaaatgccg aagaaagata agtcttctta 6601 tctcgatata attatcccca cagttttatc taccggtgga atgttaatgg cccgctatct 6661 tattattttg tttgcaccga aagctgcaag cttgggaaat actatgcttt tgatgtccgg 6721 ggccatggga gtggtcgctc ttgtaacttc cacatataac tttatgaagc aaagaaacaa 6781 ttataaaaag gatgtacaag tgtggaagga aaattatgaa aattacattc atagaataat 6841 taaaagaata aaagaatggc aaaaaagtga cataaaatat ctgaacagtg tatatccaaa 6901 catggatact ttgtttaaga atactgctga gattcacagc agcatttttt cgcgttcgca 6961 gaatgataaa gattttatgg ttatctctct tggaatgtcg gatgaagtta aacctttgtt 7021 tgagataaag agcgagaaaa aagatcatat cttttatgat atatactaca aaaaaattgg 7081 agacagaata gaaataatcc ttccatcaaa aaaggagaaa agacgtaaaa agttgtcacc 7141 cgcggaaagg gcggaagaag acaaaaacag atttttgctt acggatttgg catataattt 7201 tgccaataag gacggtgata ttgggtttaa atatttaagg agtgatgacg gaagtaaacc 7261 gcctttactg ctggatttga aatcttgcgg tactttgggg gtaatttctg aagatattca 7321 aacttcaagg aattttattc agcatgtggt gtttgaactt gcatattacc attcaccgga 7381 ggatttacag tttgtgtttt tcttcgaacc ggaagatgat cctacaaaac aaaatgaaat 7441 tttgcaaaat tacaaatatt tgcctcatgc aaacgaactt tttgatgggg tttcccagtt 7501 tgtgtttgac aaggaaagtg ccggtattgt tttcggtcag cttcttggca taatgaatga 7561 gcgtgtcaaa tcaagcggtg acaaaaatga gggtgtgaat caaaatcaaa agctgactca 7621 aattgtttgc attgtctttt atgactacaa cattaaagaa accggttttt caaaattttt 7681 accggaggtg cccaaggagg gggaacccta tgttaattcc aacgggctca cttttatttt 7741 catacagccg gtgaaagaca agctacccaa atattgcggc aatattgttg aaattcacaa 7801 ggacaatccg aatgccagaa gatgcagctt gcgttataat attttaagca gagaaaccct 7861 taacgtttta agtgaagggg atgatgatac atccaaagcc agtgatacag acaagttgat 7921 tgaatataag cattttcaga acaactatat attcaatgcg gaaaaatata gagaaaaatt 7981 tgctcttgca ttcaaacagt taagcgcaat ttattacaca agaattgctg aaaacggtaa 8041 agtgccgtca atggttactt tgtttgaact ttatggtttc gattcggaaa aagtacaaaa 8101 aggggaaata aagaaaatta tactggacaa ctggaaagac atagaaaaaa atgatgttac 8161 ccgaagcctt ggcgtaccga ttggtaaaaa cgagcatgga ccgatatatc ttgatttgca 8221 tgaaaaagct gacggaccgc acatgcttgt tgccgggatg acaggttcgg gaaaatcaga 8281 gacaataata actttgttga taggtctgtg tatgaagttt tcacccatgg atttgaattt 8341 gatgcttgtt gacatgaaag gaggaggttt ctctgaccgg ttgggggatt tgccccattg 8401 cgtcggagtt gtaacagaca ctactggaga ggaagaagga acttccgcgg cgtatatgct 8461 caaacgcttt cttgaatcac ttaatgcgga aataaagaga cgcaaattgc tgctttcaag 8521 tttgggtgtt gataatattg atgcatacat tcgtgcactc cgtattatca ggcagataaa 8581 ggaattggaa ggcaagcccg gcacggagga gacaattgaa aaattgaaaa agaagctgaa 8641 tgacaagcaa cttaaggcat taaacaaaga tttgaaagaa ttttcctatc tttcccacct 8701 tattctggtg gttgatgaat ttaccgaact taagcggttt tcaagtgaaa gcagcgatac 8761 agactttatt gctgaaatta ctacgattgc gcgtgtcgga cgaactttgg gattccatat 8821 tattcttatt tcgcagaata ttgaaggtgc aattacagat gatatcaggt tgaactccaa 8881 agcaagaata tgccttagag ttgcaactaa acaggcgtcg aaagagatga tagacagtcc 8941 ggctgcagcc gcaccgacga tgcctcttaa tggccgtgcg tatttgcttg ttggtacagg 9001 tacaagattt gaatacttcc agtcagccta tacaggtgcc aataaaaacc tcaatattga 9061 gcctccggtg gtagttacgc aggttccgaa ttcaggcaga ttcaatacag atttttattc 9121 ctcgaaaaaa gataatgaaa gagaaaagaa aaaaaatgag aacgttaatg aacatgatac 9181 ccagctcaga tatataaaca atacaataat tgaaatgagc agagagatgg aaaagccgcg 9241 tcaaatattt ttaccgccgc tctctgagaa aatttttgat gagactaaat ggaggtatta 9301 aaattggctt ttgaaaagat gctgtgtaca ttgggcaaat ttgatatccc cattattcag 9361 ttgcagccac catttgttgt tgacttgctg gattccaaca tagctgtgtt cggagctgcc 9421 atgagcggaa aaacgacctt cattagaaca ttggttaatg ttcttcacaa acaatacaac 9481 gaaaaagagg agcaaatatt tattcttgat tttggcggtg ctttgtttga ctgcagagat 9541 ttgcctttgg tctccgctta tttcgataat tcgaatgaag aatatgtaaa acgtgttttc 9601 aagattatgg ataacatact aaaagacaac atcagggaac ttaacggtaa aaattttcgc 9661 gatgcggatg ttcagccttt gcataccact tttataattg ataacgtcaa tgcttttata 9721 gatgaaccac gatatatggc atatcatgaa aaacttgcaa agttatgccg tgaaggattg 9781 tcaaaaggaa ttacaattgt tattacggca cttgatacaa aaggtgtaac ttcttatctt 9841 gggaatttta agcagaaaat tgcttttgaa ttgcctgtgg aaaaatatgc ggacattttt 9901 acgggaaaag taggtttgat caaaaatact cccggtcgtg gttttgcaaa tgttacggtt 9961 aaaccggaag gcgttacggg cacattccgg atgaatttgc cctatgaggt ccaatgtgcc 10021 cttccctaca gaacggaaga cgcagaggaa agcggcgaca caaaagaaag tttttacgaa 10081 aaactcagac agaaatttag tttttcggaa ggcaggtacc ggaaatgtgt aaaaaaatac 10141 tggacattcc caaaagagtt gacctgggag gaatacgaaa aactgaaaca gcagcctaaa 10201 aatgaacaaa aagagtacag gcttcctgta agtgtcggat tggattatgt taatttttat 10261 cctgtaactg ttgatttgga gcaatctcgt gtaattgcta tttacgggaa aaagggattt 10321 ggaaaaacca acttgcttta tctgctgctt agcggggttg tccagcaaag accggaagct 10381 gaaatcgtgt tttttgacga cggacgaaat caacttgaac ctgtttataa cagcttcaaa 10441 gacaaagtaa attgcaagtt gataaataaa tttgaagaaa tggaattgtg tttgaccgat 10501 ggaacaaaaa aaatgaggaa actgtcgccg cttcagcaat tttatttata cctgaatgag 10561 aaacatataa gtttggataa acccaattat atggcagata tttatggagt cagcaaagta 10621 tcatccaagg aataccttat gataccggac tgttacgttg agcgggcgcc gtttacggta 10681 tttgtgatac aaagcaaatt ggtttatttg aatgcagttg aaaacaagcg ttttattaat 10741 gttcttctgc cacagcttgt atccgttgct gaagaaaggg gatatttgtt tatattttca 10801 gatgtgcaaa agataagtga tgcagaacag aattcatttt ttaataatat gattaccgga 10861 gcgtttttgc ttgataatat tgccgaattt gccggagaac gcggtcagag gactatattt 10921 ggcaatatgg atgttaagtc tttgaaagag gattatgcaa ggtgcgaaat aggtgatgga 10981 tatttctatg atgtcgaggc ggataattta ttgaagttaa aatttattaa atattgctga 11041 aaggaggagt atttgtgact gactctggct ttgtattggc cgatattgac aaacttgtac 11101 aatttgaaaa gaaaagtgag gaagcaattg aagaatttga tgccattaaa aaggaatttg 11161 aaagaattaa tgaaacattg cttagcaaat ggaaaggtga aggcgccgac gcgtaccggc 11221 aggaaacaga caacatactt gccaatattg gtggtatcag agatgttctg gatgcaataa 11281 acaacggagc cgttaaggct ataaaagaaa gctatttgaa acttgatgaa gaacttggca 11341 aatttaacag aaacccccac gtggacaggg aagatggtta atgtgatttt gagcaagggg 11401 agggaaaggg tattgtatgc ctaagccatc aatcggaact gctcaaattc cagtgccgga 11461 gaaagaggaa aagccggtaa tccaggagct taccgtactt gaagaaggct caaaggaatc 11521 aatatataat ctgatttttt ctgaagaaga aaaataagat aaacaaagga cggttcaggg 11581 cttctgctca tcctactctg cattgtaaaa aggtaggatg aatttttatt tttaatctta 11641 ttgaaaaaaa tttttgaaaa tcggttttat taaaaaaaag tgggtatatt tataatagtc 11701 aattgattgg ttaaaaaaat ttaaataagc aaacagaata ataacaaaag taaggaggaa 11761 tttgttatgt cactgattgg aactgaagta aaaccattta ctgctgaggc ttatcacaac 11821 ggaaaattta taacggtaac ggagcaggat tttaagggca aatggagcat agtagttttc 11881 tatcccgcag attttacttt tgtttgcccg accgagcttg aagaccttca gaataattat 11941 gaaaaattta aagcattagg agcagaagtt tattctgttt ccaccgatac ccattatact 12001 cacaaagcat ggcatgacac atccgaagct ataaagaaaa ttacttatgt aatgattggc 12061 gatccgtccc atactctttc cagaaacttt gatgttctca atgaagcaac aggattggca 12121 gacagaggta cctttattat agaccctgac ggtgttattc aatatgttga agtatcagct 12181 gaaaatgtcg gacgtaatgc cgaggctctt attgataaaa taaaggctgc acaatacgtc 12241 agaaatcatc ccggtgaagt ttgcccggca aaatggaaag aaggcggagc aacgcttaaa 12301 ccaagcattg atttggtagg aaagatataa gaggtaagcg gatatgtttt tggacgcgga 12361 aatcatgcag caactggaac agtatttgac gttgctggaa aatgatattg ttatcaaggt 12421 taacgccgga aacgataaag tatccgttga tatggtcagg ctaatagatg aaattgcaaa 12481 acttacgcca aagattcacg ttgaaaaagc agaactcgac agaacaccaa gctttagcgt 12541 taaccgtccg aatgaggata cgggtattgt ctttgccggt attccgttgg gtcatgaatt 12601 caactcctta gttttggctc tcctccaggt aggaggaaga gcccctaagg tggatgaggc 12661 tctcatcaat cagattaagg gaattaaagg agaatatcat tttgaaactt acgtcagcct 12721 aagctgccat aattgccctg atgttgtcca ggcacttaac ataatgagcg tactcaatcc 12781 taatatcacc cataccatga tcgacggagc agtcttcaga gaagaggttg aaagcaaggg 12841 cataatggcg gtgcctacga tatacttaaa tggaaatttc ttcgaaagcg gccgattgac 12901 gctggaagaa attcttgcaa aactggggca ggcgacggaa agtccatcca ttaatgaaaa 12961 agagcctttt gacgttcttg tcataggcgg aggacctgcc ggcgtaagtt ctgccatcta 13021 tgctgcccgg aaaggacttc gtaccggtat tatagctgaa agatttggag ggcagatttt 13081 agataccttg ggaattgaga attttatctc agttccatac accgaaggtc ccaagcttgc 13141 cgaaaatttc aaggagcatg ttaaaaggta tgacatagat gtaatggagc gtcaaagggc 13201 aaaaagtata agacgcaatg aacttttgga agtagagctg gaaaagggag ctgttgttaa 13261 aagtaagacg gttattattg caacgggggc gagatggcgc aatgtgaacg ttcccggaga 13321 gaaagagttt aaaaacaaag gcgtggctta ttgcccccac tgcgacggac cgctgtttgc 13381 agggaaggat gtggccgtaa ttggcggagg caattccggt atagaagctg ccattgattt 13441 ggcgggcatt gtaagacacg taacggtact ggaatttctg ccgcagctga aagctgacaa 13501 agtgcttcag gaacgtttgt acaggcttcc caatgtaact gtgcttacaa atgtccagac 13561 aaaagagttt accgggaagg aaaagctcga cgggattact tacattgagc gtgacactaa 13621 tcaagaaaag cacattgagg ttcagggagt gtttgttcag attggccttg tcccaaatac 13681 cgaatggctg gaaggaacca ttgaacgcaa tgccatgggt gaaattattg tcaatgaaaa 13741 aaatgaaacc tcaatgcccg gggtatttgc agcaggtgac tgtaccaaca gcccctataa 13801 acagattgtt atagccatgg gttccggtgc gacggccgca ctcagcgctt tcgattacct 13861 aatcaggaat taagaaatta acagaggacg gttctttgtt tgatatcaaa cagggaaccg 13921 tccaaactat tggtgaaagt ataatagata gatttttacc ttgaaaaatc atagtatttg 13981 tctgtacgat accaattcca aaaattttgt ccttgtgtca tgagaagctg gtctaaaaat 14041 acttcaaaat tatgtccaag acatttaaac tcatcgcgca aaatatttgg tccgacatac 14101 aaataattgt tggtattggc ttctttgctg ttgattacta tataaatttc cgttttggat 14161 tcttttgatt gcggagatta tatcttgcat gctcaagtaa atcaactccc acataataat 14221 ttttttatta tttactcctg ctttaggcaa aagaacaaaa tttaacatcg acaaattaac 14281 atagttgttt atttgtatca agcagaaaaa aatatgtata tgatgccggc cgaccgacac 14341 aaaaatgtga gcgttcacga aacaataaat atataaataa gggtattaat tctgcaaaaa 14401 gaaaagtgtt tgctacatga ggtccattaa tttttatttt atatcataaa tcaaaaagga 14461 ggagaaacat gtcaagaaaa cttttcagtg tattacttgt tggcttgatg cttatgacat 14521 cgttgcttgt cacaataagc agtacatcag cggcatcctt gccaaccatg ccgccttcgg 14581 gatatgacca ggtaaggaac ggcgttccga gagggcaggt cgtaaatatt tcttatttct 14641 ccacggccac caacactacc aggccggcaa gagtttattt gccgccggga tattcaaagg 14701 acaaaaaata cagtgttttg tatctcttac acggcatagg cggtagtgaa aacgactggt 14761 tcgaaggggg aggcagagcc aatgttattg ccgacaatct gattgccgag ggaaaaatca 14821 agcccctgat aattgtaaca ccgaatacta acgccgccgg tccgggaata gcggacggtt 14881 atgaaaattt cacaaaagat ttgctcaaca gtcttattcc ctatatcgaa tctaactatt 14941 cagtctacac cgaccgcgaa catcgggcga ttgcaggact ttcaatgggt ggaggacaat 15001 cgtttaatat tggattgacc aatctcgata aatttgccta tattggcccg atttcagcgg 15061 ctccaaacac ttatccaaat gagaggcttt ttcctgacgg aggaaaagct gcaagggaga 15121 aattgaaact gctctttatt gcctgcggaa ccaatgacag tctgataggt tttggacaga 15181 gagtacatga atattgcgtt gccaacaaca ttaaccatgt ctattggctt attcagggcg 15241 gaggacacga ttttaatgtg tggaagcccg gattgtggaa tttccttcaa atggcagatg 15301 aagccggatt gacgagggat ggaaacactc cggttccgac acccagtcca aagccggcta 15361 acacacgtat tgaagcggaa gattatgacg gtattaattc ttcaagtatt gagataatag 15421 gtgttccacc tgaaggaggc agaggaatag gttatattac cagtggtgat tatctggtat 15481 acaagagtat agactttgga aacggagcaa cgtcgtttaa ggccaaggtt gcaaatgcaa 15541 atacttccaa tattgaactt agattaaacg gtccgaatgg tactctcata ggcacactct 15601 cggtaaaatc cacaggagat tggaatacat atgaggagca aacttgcagc attagcaaag 15661 tcaccggaat aaatgatttg tacttggtat tcaaaggccc tgtaaacata gactggttca 15721 cttttggcgt tgaaagcagt tccacaggtc tgggggattt aaatggtgac ggaaatatta 15781 actcgtcgga ccttcaggcg ttaaagaggc atttgctcgg tatatcaccg cttacgggag 15841 aggctctttt aagagcggat gtaaatagga gcggcaaagt ggattctact gactattcag 15901 tgctgaaaag atatatactc cgcattatta cagagttccc cggacaaggt gatgtacaga 15961 cacccaatcc gtctgttact ccgacacaaa ctcctatccc cacgatttcg ggaaatgctc 16021 ttagggatta tgcggaggca aggggaataa aaatcggaac atgtgtcaac tatccgtttt 16081 acaacaattc agatccaacc tacaacagca ttttgcaaag agaattttca atggttgtat 16141 gtgaaaatga aatgaagttt gatgctttgc agccgagaca aaacgttttt gatttttcga 16201 aaggagacca gttgcttgct tttgcagaaa gaaacggtat gcagatgagg ggacatacgt 16261 tgatttggca caatcaaaac ccgtcatggc ttacaaacgg taactggaac cgggattcgc 16321 tgcttgcggt aatgaaaaat cacattacca ctgttatgac ccattacaaa ggtaaaattg 16381 ttgagtggga tgtggcaaac gaatgtatgg atgattccgg caacggctta agaagcagca 16441 tatggagaaa tgtaatcggt caggactacc ttgactatgc tttcaggtat gcaagagaag 16501 cagatcccga tgcacttctt ttctacaatg attataatat tgaagacttg ggtccaaagt 16561 ccaatgcggt atttaacatg attaaaagta tgaaggaaag aggtgtgccg attgacggag 16621 taggattcca atgccacttt atcaatggaa tgagccccga gtaccttgcc agcattgatc 16681 aaaatattaa gagatatgcg gaaataggcg ttatagtatc ctttaccgaa atagatatac 16741 gcatacctca gtcggaaaac ccggcaactg cattccaggt acaggcaaac aactataagg 16801 aacttatgaa aatttgtctg gcaaacccca attgcaatac ctttgtaatg tggggattca 16861 cagataaata cacatggatt ccgggaactt tcccaggata tggcaatcca ttgatttatg 16921 acagcaatta caatccgaaa ccggcataca atgcaataaa ggaagctctt atgggctatt 16981 gataattccg aaaagctgag cagataatga tgccgtaaag ccggcttctg aattaagagc 17041 cggctttacg gcagaatatc tttttacggc agaatacctg ttatttccat gactttgaga 17101 gcttgtactc cggctgtacc tgtattacct ttccccttaa gtaattcaaa atcccggcat 17161 cgcttttaaa atcgaacttt agcttgtacg cccataaagc ctgatatttg gcacctaaaa 17221 gacggttgaa ggtgttgatt ccgtatttgc cgtcgcccac aacaggatgt ccgatatggg 17281 caaggtgggc ccggatttga tgggtgcggc cggtgtaaag cgtaacctca aggttgctga 17341 taccttcacc gatatccgga agttccttgt aagaaagcac tttatatcct gtaattatct 17401 caactgcgtt ttttgacttt gtgtccttga tgaaaactct gcttttcttc tcgtcttttt 17461 caaggtatgc ttttaaaata tcctcttttt tttccatttt ccctttgaca aggcactggt 17521 agtacttgct gatttctccg cttttcatct ttttgagcac catatgaaga gtggagctgt 17581 tttttgctat cataacaaga ccgcctgtgt tgcggtcaag cctgtgacaa agggaagggg 17641 taaatccgga attttcttca aattcaccct ttagcttaag gtactctttt acaaaatcga 17701 taagcgtatt ctccgtctgt gtcctgtcgg gatgcacggg tatgccctgt tttttgttta 17761 cgattaaaag attgctgtct tcataggcga ccgaaaatgc cgtttcataa ttaagttctc 17821 ccgctttggg cacgccgtcc aaaatttcat caatgatata tatgtcaacc ctgtcattga 17881 gctttacaat gtggtcctct ttaacccgca cgccatttac ctttatgtcc tttttgcgaa 17941 aggctttaaa caaggctccg ttggggagcc ttggaaaagt ttctcttaaa actttgtcaa 18001 ttcttttgtt tgccttgtct tccgtaattg ttatcgtacg cataaatctc ctttaccgat 18061 aatgaagaat atttttatac tacttcttat catttattat tgcttttatt ttgtcaatat 18121 atttgtctga aatggtttcc gccacttcag gtgtcacccc ttcggagtaa accctgcaaa 18181 ggggcatatc cgcgtcgggc aggacaaggg cccaaccgtt ctccaggata aatttcacgc 18241 cgtccaaaag ttccactttt tcctggtctt tttcggttat aagggttctc attacccggc 18301 ctttcaactc ccacggacag aaaatcttct ttttgctgac gtagaaatca ggtatttcct 18361 tgatggtttc tgtcaacgtc gtattttgga ggcataagaa ttcaattatt tttaccaggc 18421 ctgcaattgc atcgaaattg agcagaaatt gatacatgtt ttcacgattt ttgaaaaggt 18481 tgtggtttaa catttgctcc attactgcct ggggtgaggt tttggtcctc acaaccttgc 18541 cgttgtagcg ctcggccaat gtttcaataa tggatggtgc cgttatgggc acaaccacct 18601 ttgaatttgg aaccgactta aaagtaataa gggatgtcag acagaggaac aaatcatcct 18661 ttaccacatt gccgtttttg tctatcagca ccagtgtttc accgttgctg tcaatgaaag 18721 ccgcaaagct ggcattattg tcttttatct cgtcaacaat ggtgtcaact tcactcacgt 18781 tggtggagga gaaactggca accttgcagc ctaaatccgt gagcatcggt actacaatgg 18841 atattacaaa atctgacggt gaaactatgc ataactttgg cggattgttt tttatggctt 18901 caacatttac ttcattcaat atggaacgta cataatagtt cttgaagtcc gtaatattgt 18961 taagtctgct gacttcgtct ccggagcagc gtttaaagtc ctcgcgggca aaagagtttt 19021 ctattttcct ttctgtaacc ctgctgatgc ttgccccttt ggagtccata aaatcaacct 19081 tgagcttgtt tggattgtcc tcactgagct tgatgtgaat tcctccctca acggaaagga 19141 aattgattgc atggcgggcc aaaggggtga gaaggctgct taagttgaat acttccacac 19201 cgaccgaaag aatacctgat ataaaggcat gtttgaacat tctggcggag ttggcggtgg 19261 tggaacttac aacaaccttg gaaccctttt tgaatatgga accgtatgcc gcgccaagcc 19321 ttgttgcaaa ctcaggggat atgtcaacgt tgataattcc ggaaagaccg ttttcaccaa 19381 agatactttt tgagtgcttt gatccccaga taatgtttct gtccactatg gcgaagggtt 19441 caacggtttt ttgcggccat atttttatat tgggtttgat aacgaccctt tcgttaatca 19501 aacaattgtc tcccacaatg gcattttcaa atatatgtac atagcgcttg aggtttgtct 19561 tgctgcacaa aatggcacca cgaatttccg agccatactc aatgtagttg ccgtcccaaa 19621 taacactgcg ttttacggaa ctgtcccttt caatcacatt attatttccg atgacactca 19681 agctgtcgat taccgcaccg ctttctatgc ggcagttgtc tccgataaca cagggggggt 19741 tgagtatcgc accgggctcg atgattgcac ccgaaccgac ccaaacacct ttttgaattt 19801 cagttccgtt tatatcaagc tggattttgc cttcaaggac atcataatgg gcctgaagat 19861 aagcctgaag gtcgccgatg tcacaccaat agtcgtccat gacgtaacca tacatgggtt 19921 ccttcttcaa aaggagatag ggaaagaggt cctggctgaa atccactttt ttgccctttt 19981 ccaggtattt taatatttca ggctccaaaa tataggttcc ggtgtttacg gtgtcactga 20041 aaacttctcc ccagctaggt ttttccaaaa agccggttat ggcaccggac ttgtccgtga 20101 taactacacc gtattcaagg ggaacgtcaa ccctcgtcaa aaccagagtg gcttttgagt 20161 ttttcatcct gtgaaactcg attgctttgg taatattcat attggtaagg gaatccccgc 20221 ttattactat aaaggtttca tcaaggaaat cttcggcgtt ttttacactt cccgccgtac 20281 ctaaaggagt atcttcggta aagtaggtta tgttgactcc aaaattggaa ccattcccaa 20341 aataatcctt aatcttttgg ggaaggtaca tgagcgtaac gccgatctct gtaattccat 20401 gttttttcag taggttgatt atgtgttcca ttattggaat gttcattatt gggaccatag 20461 gcttgggcaa gtcgcatgta agaggccgaa gccttgagcc ttccccgccg gccattataa 20521 tagctttcat ctaaggatca tcctttcact ttactgatgc tagtaaaact cggtttgcac 20581 caactgttgg taaaaaaacg gaagtcacaa atcaaacatg taaaactgca atttaatgtg 20641 tgttacctaa tataaattat agcaggatat agcaacaaac ataatatatt tatttatatt 20701 caatataacc taaaaaaatc ctttattaat tggctgaaaa ataaactgtc ggtctatata 20761 aaattatatt gctcaaaagg gtttacttgt aacagttttt tttatataat ttccaatatg 20821 gaaggttgcc tttttataac agtcacccta cataagttaa tttgtaaagg catttatttt 20881 gactttataa tcgagacgta aaatgttaca atgtaggagt gtcaattaag agtaggaggg 20941 aattaaatgc aaaagaagaa acctgctttg tttgcggtca ttctgcctct cttaatcgcc 21001 tgtataatga ttaattcttc aatggtattt gcatcttcag ggattttgaa ggagggaatg 21061 agcggaagcc aggttacatc actgcagagg gatcttaaca cgctggggta tcttgatgta 21121 actcctacag gttattatgg cagtcttaca acagcagcag ttaagaagct tcagagaaat 21181 tacggactta aagaggacgg cattgcgggg cctgacactc tctcgcttat caaaaggctg 21241 ataaacgaaa ggactgcttc aaggtcttcc ggcggcacaa cgttgaaaga gggtatgagc 21301 gggagcagtg tgacagcttt gcagaaggac ttgaaagctt tgggctatct gagcgtggat 21361 ccaacgggtt actatggaag ccttacaaaa gaagcggtaa agaaacttca ggcaaagcac 21421 ggtcttgagc aggacggaat tgcaggaccg aagaccttgg cattgattga caggcttatg 21481 ggaagaagcg gtagttctgc ttcacaatcc gcagctacgg catccagggg agggctcgat 21541 aagaccaatt acctttattc ctggttcggt aatgcggaaa acattttcaa gataggcgat 21601 acagcacagg tatatgacat taggactggg cgcacattta atataaagag gacttatggc 21661 tataaccatg cagactgtga gactttaacc gctaaagaca cggaaataat gctcagtatc 21721 tacggcggaa gctggagttg ggaaagaaga ccgataattg ttattgtcaa cgggagaaaa 21781 atggcggctt cgatggcggg aatgcctcat gcaggagttg acagtgcgcc ggctaataca 21841 tatgtaaaat cgagaagcgg aggatatggc gcaggagaca atctcgactc cgttaaaaac 21901 aacaacatga acggagtgtt tgacgttcac tttttaaaca gcaagactca tggaaccaac 21961 agagtggatg aaaatcatca gaaggcggta agggaagcgg cagagtgggc tgcaaagaat 22021 aagttttagg cgtgtataat aatttatgtg tataataatt tagactttgt aaaacgggag 22081 ataccacttg gaggtatctc ttttttcatg tttgttaatt tgaattttgc ttgtgacaaa 22141 atacagtaaa ttattacata aaagccgatg tatataatga ggtgtcgcaa aaggataata 22201 aaggtgaaga gcggttttta ccggaagatg aaaataagtg ggtattggaa aattaaatga 22261 aatagtaaag gtaaaataat aacggtaaaa gctaaatagt attggcaagt tagatacaag 22321 tcagataaaa ttttaaaaaa tgttggaaag tactaaacgg cacttgaaaa ctaattttga 22381 aaggaacggt ggttttatga gtttttacag agaaataagc aaatactatg attatatttt 22441 ccccgtcgga gaaaatcaat tgaattttat aaaaaattgc gcaggaaagc ccggtgggaa 22501 aatccttgac gtggcctgtg gttcgggagg atattcggtg gaactggcaa aagagggcta 22561 tttggtaaca gctgttgata ttgaggaaga aatggtggaa aaagtaaaaa agaaagcatc 22621 ggaaaacggc ctttccataa acgcctttaa atgtgacatg agggagcttg aaaaaaagat 22681 tggggaacgg tttgatacta tattttgtat aggcaactct ctggtgcatc ttacaagcct 22741 gaaagagata accgatgtcc tcgggcaaat gaggcgcttg ctggcagagg gcggttttct 22801 tgtgcttcag atagtaaact atgacagaat aataaagtac aatctggacg gtcttccgac 22861 aataacgaat gatgaaatag ggctggaatt tacaagaaaa tacaggtaca aaaaagaaag 22921 caacattata gagttcaata cctccctgaa aatcaaaaat ggagattgtg aaaccgaata 22981 taacaattct gtggagctgt tgccgttaaa aagcggtgaa cttgccgcag cgcttcgaaa 23041 tgcgggtttt tcagcctttg atttttacgg ggattttaaa tactcggatt atacggaaga 23101 ttcccacttg ttggtggtga aagcccggta gaatgcaaaa aatatggaat gcaaaaaata 23161 aatggggaca aaataaataa agacaataca aaaatataat cacaggggaa agtatgctgg 23221 taagacttgg ctatgttgca atgactatga acttaaaaga cagttcgcct tccgggaccg 23281 taaccgtaaa aacccttgca ggattgaacg aggatgaaac aaggcttaac aaattacgga 23341 aggttaccgc ggcaaatctg cacaacacac taaggatact aaggtataac aaagcataca 23401 acatcagtgt gtaccgtttt acatcaaaac ttgtgccttt ggccacacat cccatggtat 23461 cacactggga ctatgtcggg gagtttagaa atgagtttaa gagtctcggt gactttgtaa 23521 aggaaaacaa tttcagggta agcgcccatc cggaccacta cacattgctc aactcacctt 23581 caaaagaggt ttttgaagct tcggtgcggg accttgatta tcacgtaaaa ctgtttgaag 23641 ccatgggtct tgaagattac aaatacaagc tggtaatgca cataggcggg ctttacaaaa 23701 acaaacaaac gtctgttgaa aggtttaaag aaaactatgc catcctccct gacagaatca 23761 gaaaaaggct gatctttgag aatgacgaca agatatatac tgccagggat gtgcttgaca 23821 tctgcaagga gctgaaggtt ccaatggtgc tggatgtgca tcatcacaac tgtgtaaaca 23881 atggagaaag acttgaagat atgcttaagg aaatatttga cacatggaaa gatgagtatt 23941 ttccgcctaa aatacacttt tcaacgccaa aaagcaaaga aaacttcaga agccatgccg 24001 atgaaataga tgtaaatgag ttttaccggt ttttacagat tgcaaaaaag ttaaaaaagg 24061 attttgatgt tatgattgag gcaaagaaca aggataatgc attatttaaa ctttccaggg 24121 aattgaaaac ctttgatgac ataagatgga tagatgaagg acattttgaa atccggtaaa 24181 ttttgcaatg tcgctgttta taagaagaca taataaattc cgcaaattcc gatatgacaa 24241 aaaattccgg aggtgtaaaa caaatgggaa cgcccgatac cgggaaaata aagcactcag 24301 atatgcttat agaaacaatc aggaatgcca gcagccaaat gagctttgat gagtacgcaa 24361 aagttaccgg attggacaag gaatttattt ttgccatatt aaacggagaa attgaagagg 24421 tggacaggga aacctggaac agactgtctt tgaaaaactg acctgaattg aattgcaaac 24481 gaaaaaattt tctttgactt aagtgctata aaaaccttga aataaagagg attatattca 24541 tatttgtcga attattatca atgtataaaa gtttgtcaaa atggcttgtc caggggcaat 24601 atccgatgaa attcagggaa tgaccgtaga acaggctttg atatatattt cacattttac 24661 acaatatgga aataaataga gataaacagt tggtattatt tgaaaaagtg gaggtatatt 24721 gtatgaggag gtcaaaatat tctctcgtgt tgtcattcct ttgtttctta gcaattctga 24781 cagtgacggg gtgtagtctg gggggaaaag tgcaggcgcc gaacgaatat actcgcgtgc 24841 aggctgctga aatagaagag cctgccgagg atgtggaaat agaattttgg acgtataatg 24901 acggctggaa agctcctata aaccattttc aattgattca tcccaaaata aaaataaaac 24961 ttgtcaaatt tgattttaac gatatgggca atgtatataa aaaagcgttg gcagcgggag 25021 aagggcctga catattgttt tttgacagcg cttattacag tcagtttacc acgggagaat 25081 atcttgaaga tttgctcaaa gagccttatt atgcaggaag gtacgaaaaa gattttccga 25141 aggatatatg ggaaagcaat aaatcacttg acggaaagcg tcttttggca atgactttcc 25201 tgacatcacc cgttgtgact ttttaccggg cggatgtaat ggaggaaaac ggttttccgt 25261 cggaacctga agaacttgcc aaatttattg aaaaaagcga aaatcttatg gctatagcga 25321 aaaagctgaa atccaagggt cagtacattt ttcagatgcc tgtggatatc ataaatcttg 25381 ccggtctgta ttcgggaata tttgatgaaa acctgagatt tgtaagaaac tcagacttgt 25441 ttgtgcaagc gctggatatg gcaagggaaa ttaaaaggct ggatttgtca attggtgcaa 25501 atattgtgga ggaagcggca aaggaggctg tccggaacgg agaactggta atggtgctgg 25561 gcatcgggtc gtgggggacc agtaccatac agagctatgc tcccgaccag gcaggtaagt 25621 ggagggtcac tgcgccgccc ctggggctta aggtatggta ttcggatacc aagcttgcga 25681 ttaatgccca aagcaaatac aagaaatggg catggctgtt tgttgaatat gtggcaaccc 25741 agcaggaggg cggggagaac attgacatga tttccggcta ttgtcctgca agaagaaatc 25801 ttaaagttat gctgagagaa aacgagtatt tcggtaatca gcatattcag ccgcttattg 25861 aagatttggc agaggaaatg gttcagtaca ggcagactcc tttggatgac agggcacttc 25921 aaatatttaa tgaggaaata ttcagagcca tcgaaaacaa tgttgattcc cagaaaacga 25981 taaaggatat tgcaaataaa gtggaatatg agctgaaaaa ggatcgggaa gctttactta 26041 aggggaaaaa gcgggtaaaa tagacatatc actacataaa aggcaaggag aaagacacta 26101 tgataacatc tgtggctctc aaccccgcag tggacaaaat ttattttgtt gacaacttcg 26161 aaccgggaag aatgtaccgg gtgcggcaaa tggtaaaaac ggccggggga aaaggtgtaa 26221 atgttgcgcg ggttgcccgt atgttgggag aaaatgtccg gctgacaggc tttaaaggcg 26281 gagagacagg taactggctg gaatcgcagc ttaagaaact gggggtcgtt acaagatttg 26341 ttgaagtatc cggtgagaca agaacaaaca acaatattat agacagagta agagacagtg 26401 agacggaagt actggagccg gggcctttta tatccggcga agacatggaa aaattcatgg 26461 aggtttataa agaggctctt tccgattcca aggtcgttgt gctgtcaggc gggcttcccc 26521 agggagtgcc tgcatgctgt tataaggctc ttattgaaga ggcaaaaaac tttaatattc 26581 ctgttatact tgacagcggc ggagatgctt taaaagaagg cataaaggca aagccaaatg 26641 ttataaaacc gaatttgagg gaattgggaa gtctcattca aaaagaatta agggatatgg 26701 acgaaattgt tgaggcgctg aaagaaatta atgcagacgg aatagatatt tcaatggttt 26761 ccatgggcga caagggagct gttctgtgca cgaaagattt gtgccttaga gtaaaagtgc 26821 cgcatgtgga gacggtaaac accataggct ccggagatgc catggtggca gggtttgcag 26881 cgggacttgc aagagacaaa acaatggaag agtgcctaag gcttgcggca gcctgcggcg 26941 tgagcaatgc gcgctttttg gaaatcggtg ttgtggataa gaatgaagtc gaaatccaaa 27001 agaacagagt ggaaattgag agaatatctt gattccgctt tttttattgt ccgacacata 27061 tatttctttt caaaccggtt taaatttaaa tccggttttt aatttttatg aaggaatttt 27121 gccgttgcaa ccggcctgat tttaaattta catcaggctt gattacttta ttgctttatt 27181 tatataataa atgagggaaa aagaaatata tttttaatat acttgcaaaa atacggttat 27241 ggggccggac aataaagtat attaaaaaat agaggtattt acattctata aaataacgca 27301 tggaggatag agatgtcaga tattatttcc acacttgtaa aagagtttaa tctcaagcct 27361 ttccaggtgg aaaacaccgt aaaacttatt gacagcggca ataccattcc ctttattgca 27421 aggtacagga aagaaataac gggagaattg aacgatcagg tgctaaggca gcttcatgaa 27481 agactgattt acctgaggaa ccttgaggca agaaaagaag aagttcgacg cctgattgac 27541 gagcagggaa agcttaccgc ggaaattacg gcatctcttg aaaaagcgac caccctccgg 27601 gaggttgaag atatatacag gcctttcagg ccaaaaagaa gaaccagggc gactgttgca 27661 aaggaaaaag gacttgaacc tttggccgaa attattatgg cccaggaact taaaaccggc 27721 agtattgaag acatagccaa gccttttata aatcctgaga aggaagtcaa taccgtcgag 27781 gatgccttaa acggagcaat ggacataata gccgaagaca tttcggacaa tccgcatatc 27841 agaagtattg tgcgggacgt gtttatgaaa caaggaatga ttgtgtccaa aaagaagaag 27901 gatgaagatt cggtatacag aatgtactat gatttctcgg aaccggtggc aaaaatagcc 27961 ggtcacaggg ttcttgcgat aaacagggga gaaaaggaag agtttttgca agtcaaaatt 28021 gaagttcctg aagaaacgct tatggagcag cttaaggcga aacttgtaaa gaggcctcct 28081 tccataacgt cggaatatgt agaaaaggcg ttggcggact cttatgagcg ccttattttt 28141 ccttcggttg agagggaagt aaggaatgaa cttacggaga atgccgagga acaggcgata 28201 aaggtctttg cgaccaatct taaaaatctt ttgctccagc ctcctgtgaa aggaaaaacc 28261 gttttggggc ttgaccctgc atacaggacg ggctgcaaaa ttgcagtggt ggatgagacg 28321 ggaaaagtac ttgacactgc cgtaatatat ccgacacctc cccagaacaa ggttgaggaa 28381 gcaaaagaga ttatgaagcg gcttattgag aaacacggtg ttgatataat atcaataggc 28441 aacgggactg cttcgaggga gtctgaaata tttgtcgccg agcttttgaa ggagatagac 28501 agaaaagttt actatatggt ggtaagcgaa gcgggagctt cggtttattc cgcttcgaag 28561 cttggggcgg aggaatttcc cgactttgac gtggctttaa gaagtgctgt gtccatagcc 28621 agaaggcttc aggacccatt ggcggagctg gttaaaatag atcccaaatc cataggcgtg 28681 ggccagtacc agcacgacat gaatcaaaag cggctgagtg agactttgca gggcgtggtt 28741 gaagattgtg taaacagcgt gggcgttgac ctgaatacgg cctcaccgtc tcttttgtct 28801 tacatctcgg gaataaactc cgtaattgca aaaaatattg tggaatacag ggaaaccaac 28861 ggaaagttta aaagaagaga agaactcaaa aaagttaaga aactaggtga caaaactttc 28921 gagcaatgtg ccggctttct taggatacct gacggagaca atgttcttga caatacttcc 28981 gtacatccgg agtcttatga ggcggccaaa aagcttcttg atattatggg atacagcctt 29041 gaagatgtga agaacagaaa acttgatgga cttgtggaaa aagtggagaa aatgggtata 29101 gaaaaagttg ccagggagat tggtgtcgga gtgccgactt tgaaagatat tataaaagag 29161 cttttaaagc ctggacgcga ccccagggat gagcttccga aaccgatgct tcttaccgac 29221 gtgctgcatt tggaggattt gaggccgggc atgatattga ccggaaccgt aaggaatgtt 29281 gccgactttg gtgcctttgt ggatgtggga gtgcaccagg acgggctggt tcacatatcc 29341 gagcttagcg acaagtatgt aaaaagtccc atggatgtgg tgtcggtggg ggatatagtg 29401 aaggtcagaa ttttggatgt tgatgttgaa agaaaaagaa tatccatgag catgaagggt 29461 gtcaattaag gttgtttttc aatagaatta attgattctt aataaaaata aaataaataa 29521 aaaatagaaa aagattggaa gaaggtttaa aacatgagca atatcactgt aaatattaaa 29581 aagcttgcga aaagacggga tataattatt gcctttgcag ctgtgacatt tttctattgc 29641 tttattgaat ataatttaat atttcctgta attttgggtg tgacaaccat aggcggagga 29701 aattttctgg acagcatatt gcatactatt cagcttattt taggactttt gtccaatgta 29761 aaatacatac tttacggttt ggcggccgta acggttgccg ctttggtgtg cggatttgtt 29821 ttatcaggct gtttttacaa aataaacaat tttctgtcaa acaggaaaag aataaagaca 29881 gagtttttca aaggtgtcca aaagcatttt tttgaggatt tctgtgatat cctttgaagt 29941 aattcttttt tcgatattgt ttactatatt tatgcttata gtgactgtgc cggccgtcgc 30001 gatcacaagg tcatttcttg ggggaaagac ggaacttttg gctcttacgg ttttgtttga 30061 tttaattact ttgatggtgt tgttttttgg atttatgttc tttaggattt atatggcttt 30121 ttggtatcct gcggtgttta atttcaaaga cagttatttt tcaatcggta aatatgccgc 30181 ggatacatat ttttggaaaa ttgttgtcat gtttttaaaa tttgacgtgg catttattct 30241 ttttgagttt gttctgatat tccttaattc tgtactgcct gtaagtggag ctttggcgtt 30301 cttgcgtata tttcttttaa tgtttgtcaa ttgggcggta aaaactttgt ttttcattgt 30361 ggttacgata tccgttttct cggtgtttct ggattttaag aaaaaagtaa ccgaataaaa 30421 atagtttggg gaagtatgag agggattgct ccgtcaaact tccccgacat tgttagattg 30481 caaaattgtg tttcccgatt acctttacga tttttcttga ccatatccat ttgctggtgg 30541 cggttctggg gttgtagtaa tacaacgctc ctccagtggg gtcccagccg tttaacgcgt 30601 cttttgcagc tttgtacgca gtttcattgg gtgcaaggtt tatctgtccg tcgcttacag 30661 cgtcaaatgc gccgggttga taaataacac cggctattgt gttgggaaat ctgctgtccc 30721 ttgtcctgtt gatgacaact gctgcaactg ccacttgtcc gatataaggc tctccccgcg 30781 cttcgccgta aacgaggtgg gcaagaagat ccagattcct gttgcttgac ggctgggcgg 30841 atgttgcttt ggcagcttgt ccggtaggga gtcccaaagc cgccaatgtt tccggacccg 30901 ctattccgtc caccttcagg ccgtttttgg cctggaattt gcggaccgcc atgtaagtct 30961 tgtaaccgta aattccgtct attttgccat tgtaatactt ccaaattgca agcttgtact 31021 gaatgttttt aacttcctgc ccggttgagc cgtaatatga cagtgcagcc ttgctgtaac 31081 cgtataaact gtatatttcc tcccaaaaaa cgacggctga acttaaaatt gacagtattg 31141 ttattattac aatgattgat aatacccttt ttcgcaaagc cattctcctt tgtcaaaaaa 31201 tattttttta ttaataagta ttgttgattt gagaatgaaa tatttatata ttcttatttt 31261 gtctatttct gatttaaatt attatatgtg aaaaaatata acaaaaggaa aatgtctttt 31321 tgaaggaaaa cagagtaaaa gcgaggaaac ttgttgtaac ctcgctgtat agtttatgct 31381 ttatttagga caattatatt accaattata ttaatattta aaaaagaata catgaaggaa 31441 actgttaaat atgacgtaac aatttcctag acggatttgt tctgtaaacg aaaatactct 31501 tcaaatattt cagacactaa aagatagata agtactatca gcaaaaagtc gtcatcaatt 31561 ccctccgcga ttagaataaa tattaagaaa agaaggatta tttcatcgga atgcagcttt 31621 cggaaaaaca tggacggtga acgtgaacct gctgccggca ttgcatcaaa agcggtttca 31681 tccttctcgt tgggaagagg aatcttttca acttctctta aggtatcacc ggtgggatta 31741 accgcatttc ctgaagcaaa gctgctgtcg ggcatgtatg atatgttttg tgccgcggcc 31801 ggaccatatc ttctgaacct tggatccctc ttgtatatca ttatggtgcc cctttcatat 31861 agttttttca ggatcgctca taagctttgt tatctgtgtt acttgaaaca gccttataca 31921 gttggaaagc tttttttgtc ttccactgct taaaaacggc tttatggcgg taagcagatt 31981 tattcttggg tcgttaatgt ttctcatggc gtccatgaca tcctttattc tacgcatcat 32041 ttccgcatta tcctgaagtt cgtcaatgtt tctttcattc tctttggtat ccgactgcaa 32101 tggtaagttt tcagctttta ttgaatcctg ggcttttatt ttcattgaag gttcttcttt 32161 tggagatttc tcctccgatg aggtttgggc gggcttgtca ttgcccgaag attttgcgag 32221 catggaaatc aggctcgaaa gattttcgga cattttttcg ttgccgttca gcatgtctgc 32281 gagctgcttt agtttattgt taagatcatc actcattacc ctgtcacctc catggatatc 32341 cgacttgcct ccgggcttgg actgcggtac agtgcttgtt gtccggtttt tcagggtttt 32401 tccaggattc ctttcagttt ttctacaatt tcgtcgccgt gttcgccaag taactgtgag 32461 agcttgctaa gatctgcatc ggtgattttt tgacgtattt cgtctttgtt gatgttaaac 32521 tcctttagct tcgactcgtc aaattcattt attttttcga ggagctcgtt tttatctatt 32581 ttgttgattt tttttgaaag ttcgtccacg tcaccgtttt ttagcatttc tattgccgta 32641 tttattctct tctcaagcat tttttggtcc atttttccaa acagttcgga cagctttttg 32701 ttgatatcaa ccatcttaac ccaatccttt caatcgttat ttttaaattg aatgcctaaa 32761 tgaatacaag tattgataaa ttatttatct aataatttat atttggggaa tggcaaagat 32821 agaacttttt taaaaaaaga atcccttccg tacagggtat ttcgaaacca tgatatgaaa 32881 gacaacttta attttatcaa aaatcaaaca aaggaggagg gaagggaaat tttttcagca 32941 ataaaaaagc ttgaggaata ccaggataaa gaacaatatt gtgtcgtcat ctttaacatc 33001 atgtttaatg ccgcctattg cgctgctgtc ataaaagagc aggagaaata ttaaaataaa 33061 gaacaaaagc tcggaattat ttgtgcgctt ttttatatct gacatggttt tccacctccc 33121 atttattatt cctgctgatg tttacataaa cacggacggt gttttgacaa cagcatgcta 33181 ctatattata tgagccgggg aaaagaagtg ttaattgata tgttgtgttt tggacggcgt 33241 tactttaaga tataaaagag tactgttttt gaaattatat tttgtgtatt aaatttttgt 33301 ttgggtggta aataaaatag aaaaacggcg cttttttata agaggggtgc atatgtttgg 33361 atagttctgt ttatgtgacg gcttttgcag aaggtatact gacttttgtt tcgccttgta 33421 tttttccgat gcttccggca tacttttcat acttggccgg atttagcgat aaagaagata 33481 aagatgggaa gaataaaagg agacttttga taaattccct tggatttgta ctgggattta 33541 caatagtgtt tacgctgttg ggagctgcag ctacttcttt gggagcattt cttaaagaac 33601 acagagatgt tttgaaaatc ataagtggta ttgtgataat catttttggg cttaatttta 33661 tcggcatact caacataggc tttttaaaca gggaaaaacg gtttgagtac aaggcagaca 33721 gtttgaaatt cgttggttcg gttattttcg ggttttgttt tgcgtttggg tggacgccct 33781 gtataagcta ttttttagct tcgattctgg ctttggcggc caattcttcc accatgccgg 33841 agggattgat gctgcttgtg gtgtattccc ttgggcttgg gatacctttt attgtttcgg 33901 ccatgatttt tgaaagtatc agggaggctt tcaattttat aaagtcaaat atgagaataa 33961 ttaatattat ttccggaatt ttactgatac ttttgggagc tgcaatgctt tttaacataa 34021 tataattttt agcataaata ttatttgaaa tttgcaatta tttaaaaatt tgaaagggag 34081 atgaatatga agaaaactgt aaatatcgta atctggacgg cggtgctggt attcctcata 34141 atcggggcat atttcgtata cagcaggaac aattcggcag aatatataga agataaaatt 34201 gcggaagaca caaataatga caaagctgca ggtgataacg gcgggaccaa agaggaaaac 34261 aagataatgg caccggattt ctccctgaaa gaccttgacg gcaacacggt aaagctgtcg 34321 gattacagag gaaagattgt gtttttgaac ttctgggcat cctggtgcgg tccgtgtaca 34381 tcggaaatgc ctgagtttga aaaagtccac aggcagtttt caaaagaaga tgatgcggta 34441 attttggcgg taaatcttac cgacggcttc agagaaactg aggaaaaggc aagaaaattc 34501 atagccgata acggatatac catgaaagtg ctcctggata cgacgggaag tgctgcgaag 34561 gactatggca tatacagcat tcccacgacg tatgtcataa acagggatgg aagtatagtc 34621 acctatatgg aaggagcaag accgggaaag gtgcttttgg atatatatga aaagctaaaa 34681 tagcgctaaa tgcaaaaata aagaacagga ggctttgcca tgaatgacgc aatagttaaa 34741 tcaacgatgg agaactttga caaagatgtg ttaaaaagtg acattcctgt ggctgttttg 34801 ttttatactg aaagctgtcc tgtttgtgac gcttttatgc ccatatttga gaggacggct 34861 caaaaatacg gcaaatacat gaaatttgtt aagatttacc ggcagcagaa ccgtcaactg 34921 gtggaagacc ttaagataaa gagcagtccg acggtactct tttataaaga aggcaatgag 34981 gtttgcaccc ggttgaacgg ttacataagc aacgcagagt ttgtggaagc catagagagg 35041 gttattggag atgtttgtaa aggagagaag agggaaaagg tacattgtga ttttctgata 35101 ttgggcggtg gcccggccgg cttgactgct gcgatttacg cggccagggc aaagcttcat 35161 acagtggttg tggatgaagg actcattgga gggcaggtgg ctacaacctt ccaggtcgca 35221 aactaccccg gtacaaatgg tgttgtaagg ggtattgacc tgatggaaaa catgaaaaag 35281 caggcgctgg acttcggtgc atatattgac gacctcaaag agatttccga tgtaaatctg 35341 gagggaaagg aaaaacttgt aaccgcaaag gataccgact attatgcaaa agccgtgctg 35401 atagcaaccg gagcaactcc aagaaggctt ccggccgaag gtgaaaaaga gtttagagga 35461 agaggtgtgc attattgtgc cacatgcgac ggtgccatgt actttgatgc caacatcctt 35521 gtggtgggag gaggagagtc cgcggcggaa gaagctgttt ttttgactag atatgcaaag 35581 catgttacaa taataaacag gcatgattat ttgaaagctt caaaaactgc ccaggatgag 35641 gtgttcagga acccgaacat cagtgttgta tggaattctg aagtacgaaa gattaacggt 35701 gacagtttcg taaaaagtgt tacaatagaa aaccttaaaa cagggaaaat tgaggaaata 35761 gagactgacg ggctgtttgt ctatattggc acgcagccaa aaacggagct ttttgccggc 35821 aaggtcggta tgaatgaaga gggatatatt ctgacgaacg aggatatggc gacgaacatt 35881 ccgggagttt ttgccgccgg agacgtccgg gccaaaaaag tccggcagat tgccactgct 35941 gtcggagacg gcgcagtagc aggaataatg gcagaaagat atattaacgg aaaattctat 36001 taaaattgcg taatgaaaat tacgataatg ttatatgaaa ttggaggaaa atttgtatgt 36061 atgacgtgat aataatagga aagggacctg cagggatttc cgcatcattg tacacagtga 36121 gggctaacct taaaacattg gtcataggaa agggagacag tgcccttaaa aaagccgaga 36181 gaatcgagaa ttactatggt ttttcagagg ccataagcgg agagcggctt ttggcagaag 36241 gtgagaaaca ggcagcaaga ctgggagtag agataattga aagtgaagta atcagtattg 36301 aaaaaaatga attttttgaa gttttgacct ccgacgaccg ttatatggca aaggctgtgc 36361 ttatagccac cggacaacct cagaaaaagc tgagaataga aaaccttgaa gcttttgagg 36421 gaagaggggt aagctattgc actacctgtg acggcttttt ctacaacaac ctcaaggtgg 36481 gagttgtggg cgccggagac tatgtggtgc atgaggccat ggaacttctc gcttttacga 36541 aagatataac aatatacacc aacggtaatg aactgcaagt atccgaaaaa tttgttgagg 36601 cggcaaaaag attcagaatc agcaaaaaac ccatatacaa gattgacgga agcgagtttc 36661 tccaaaaaat ctttttcaaa gacggtacca gcgaggatat tgacggtttg tttatagcgt 36721 atgagagtcc ttccagtgtt gattttgcca gaaagcttgg cataattgtt gaaggaaatg 36781 ccattgtggt tgacaaaaat caacagacaa atcttgaagg gctgtttgcg gccggtgact 36841 gcaccggcgg tttcaagcag atagcaacag ccgtggggca gggagctttg gccggcagga 36901 aaatgattga atatgtgaga agcctggaga cggcaaacag tcccgtttga gtctgaaacc 36961 aaagtggaat aatatgggcg gttgattttg aattttacat atgttaatat aatagttaag 37021 gtattttatg tgaaaggatg atgaagctat gggtgttcga aggatacaaa agcatatttt 37081 cagacggcac ctgtatgccg atttccttga gcatagtacc gtaagtaata ctatgtctgt 37141 gaccctgtga ctttgtcacc gggtttttta ttttatcaaa aagcttgctg tttaagcttt 37201 gcagggatgg aggagaaaaa atgctgccga acgttgccgt agaattcgat gaaaacagta 37261 ttttccgaag tttgggcaag ggcaacctta ctttcaggga ggcttttgaa gaaattataa 37321 agtttatcga ggcagacacc aacagttctt atagaatttc cataggaact gattcccatg 37381 tgggcaacgg tactcttttt gtcacatgca ttcatgttca caggattgga aaaggggcta 37441 tcggatttct tcacaaaagt ctgatgtcaa ggcctataag gaatttacgg gagaaaattt 37501 acatggaaac atgtatgagc ctccagctgg catatttgtt tgacgaggaa aagattgacc 37561 gtatatacaa agctttgggg aaaaacggga aatctcccac caaaggtgtg acttttgaat 37621 ttcatattga cataggaaaa agaggagaga caaaagcact tataaacgaa atggtgggca 37681 tggtaagcgg acttaacttc atccctaaaa taaagccgga cagctattgt gccagttgct 37741 ttgcggacag gtacaccaaa gccatataat tgccgcaaaa agccagagcg aatgttattt 37801 tttgatgaaa agcgaatttc aaatattatc ttgattttaa atattatgtt aataaaataa 37861 aaacaaagag catgggaaga taagcatatg ttggtaaaat attggcattg tagctttata 37921 taatgtcaat ttttttgtat tctcaagatt gaaagctttt tgagaagatg atagagtgga 37981 tataaaaaaa ttttattttc aaaatatttg ggaaaatatt attaacggga caaaaaaacg 38041 tattacgttt ataattaatc taaatgagaa aggatgaaag tattttggat aaaaatacag 38101 taatttcgat gattgatcat gctgttttaa agccggaagc cacggacaac gatgttttaa 38161 gagaatgtga aattgcggca agatacggtg ttgcttcagt ctgtgtaaaa ccatgccatg 38221 tggcgttggc ccgggaggca ttaaaagact caaaggtaaa agtaagtacc gtcataggtt 38281 ttccccacgg ttcaactaca actgcctgca aagtgtttga ggcggtggaa gccatggaaa 38341 acggagcgga agaactggat atggtgataa atatcggaaa acttctgaca ggggattatg 38401 actatgtaag agaggatata aaaagggttg tgtctgttgc ccatgagaga ggtgttattg 38461 taaaggttat tattgagacg gctcttcttg accttaacca caaggtgcag gcatgcaaac 38521 ttgccgagga ggccggtgct gattttgtga agacttccac cggatttgcc ggcaaagggg 38581 caacccttga agacatatgt attatgagag gcgctgtggg accgaacatg aagcttaagg 38641 catcgggtgg aataaaaact tttgaacagg cggcggagtt tgtaaatgcg ggatgtgaaa 38701 gacttgggac cagctctact gccgctattg cagaagaaat tgggtaagat ttttttggga 38761 taagaatact ggatgcctca ccggcataaa aatatcctat aaagatataa agaatttata 38821 gtgaggtgtc cggttaaatg cgaagacttt tgtgtgttat tactgtatgc atcatgatat 38881 tatccttttg tgcaggttgt ttagataacg acaggtttgg attgggagac aacgaagaag 38941 caagtgttgc aagcagcatt gtgctaagtg aggctgatgc ccggcagatt gccgacaaat 39001 cgccgatacg tctttatttt gcaaatgagg ataattccaa actaaagctg gagataagat 39061 atataccggt tagtgaaacc accaaaagtg taaaccacct tgccgaaata attgtcaacg 39121 aattgatcaa aggtcccaaa gttgcaggat taaagcctac aataccggaa ggtaccaaac 39181 tacgctcagc gataaagatt gagggagacg ttgccattgt cgattttacg aaggagttca 39241 gggataatca tccgggagga aaagcggaag aaagaatgac aatttactcg gttgtaaact 39301 cgttgacgga gctgaaggag ataaacaagg tgaaattttt gatagaagga aagtcgtctc 39361 ctgacttcaa gggaaatttc agatttaata ccgaatttcc aagaagtacc cagctgataa 39421 gcaataaggc ggaaccggtg gggactgtga acagcaagga tgcggcggac aaaaaagatg 39481 attcggcttc cggagacaaa gataccgctg atgtcagcaa tgagacggaa aacgagagtg 39541 tcgaaacggg agcccaaaca tcggatgatg aagaagtttt tgttgatgat tccttagacg 39601 gcgaagcaca ggaaacttac caggaaacca acgacgatga aaagtggcag gaaacttacg 39661 acgaggcttc cgatgaagag gcccggcaga catttagtga tgaatttgaa gaaacataca 39721 tagaatacct tgaataatca aaatttatat aatgccgatg tgaaagggtg ctgcattaat 39781 gactgcagca tcctccgcat ttatgaatat tggggcattc cccgccttcg gattttctgg 39841 attgtataat attcacgctt ttaaatacag catcaagttc gttgctgccg cattcgggac 39901 atttgatcag tttttcggtc cgttcgctca tttttgccat tacattaaac tcatgcccgc 39961 actttgaaca tttcaaatca taaaaaggca ttataatctc ctccgtttgt tgttttgttg 40021 acaaataata ttatactata aaattcaaat aacaaagtat agcatttcta ttggcctttt 40081 gttataataa tgaagtcgaa aaaataaaag gtaatgcttt attttaaagg attttcacca 40141 gtttatttta tttttttcag ggggaataaa agatgactgt tagtggggtg ttaagaagat 40201 attttgcctg gcttattgat agtattatac ttgccggatt aactttcgga ctgacaatgt 40261 ttttggaagc tttgggtgtg ggagtgcctc ttaatgaatt ggttcaggca atgatcagaa 40321 aaactgaaca gtcacttgag gtaattaaca gttttcaatt ggaagtttgg gccatatacg 40381 cggtattgtt ttttatatac gaaatcgttt ttgtggcttc cagtttatcc gccactccgg 40441 ggaaaataat ccttggcatt gaaattgtaa gcgacaggaa aagcagcatt gacaaggtta 40501 ttataagggc actggttaag tttataggtg aaatgtttcc tttttccctt gttaatttta 40561 ttatagtatt agtcagtgga aaaaaacagt cattgcatga caaagctgca agaacgtacg 40621 tggtttacaa aaaggttgag aataattatt caaaaaaaat agatcccaaa gagctgtttg 40681 aggaaatgaa aagaagggga cttagaactt acagtgagca attggcgttg gctgaagaac 40741 tgtatggcaa aaacagaaag aaggccagga cgtcagcttc ctatggatgg ataagtttgg 40801 tgttgcttat tgttggattg gttttgtttg gtgtgttttt ctcaagatat ctttcaatat 40861 acagagaaat atatacagat gcatttataa gagattatat acactataat taagagatta 40921 tatacactat aatattgtga ggtagtagtt taaacggata actggaggtg gtagttatgg 40981 attctggacc tttaccttgt tgtggtaaca aaaaatatca caatatgttt ggagccatag 41041 ctaccgttgg ggtggtgtgt ggctctgtca agggagggct gcacaatgaa agaaatgatt 41101 ctggagctca ttgaacaagg caaatatgcc gaagtgagaa acaaaattac tgaaatgaat 41161 gaagttgaca ttgcccaact tttggaagag acggacaagc ataagctgct ggtgatattc 41221 aggatattgc caaaggatgt tgctgccggg gtcttttcgt atatatcata tgaattacag 41281 agatatattg ttgaatccat taccgacagc gaaataaaga acattttgga tgaattgttc 41341 ctggacgata caattgactt tttggaggaa atgccttcaa acattgtaaa aagggttctt 41401 aagaacgcgg atgaaacaac gagaaagctt ataaaccagt ttttgaacta tcctgaaaac 41461 tcggccggga gcataatgac catagagtat gtcgacttga aaaaggaaat gacggtaaaa 41521 caggctttgc agcatatcaa ggagacaggg atagacaaag agacgattga tacttgctat 41581 attttggatg actccagaaa acttgaaggt gtaatatcaa tcagaaagct gatattaagt 41641 gacgagtccg tggtaattaa agacatcatg gatgcagatg taatatatgt aaacacacat 41701 gacaagcagg aagaaattgc agcattgttt aaaaaatatg attttctttc catgcctgtg 41761 gttgataatg aacgaagact ggtcggtata gtgacaatag atgatattgt ggatgttatt 41821 gagcaggaaa atactgaaga tttccagaaa atggcggcca ttcagccttc cgaaaaagag 41881 tatttgaaga caaacgcgtt ggtattggcc aagcacagaa tcacatggct tttggtattg 41941 atgctttctg caacttttac gggcaatatt ataaaaaaat ttgatgaagt attgcaatca 42001 attgttatac tggcttcttt catcccgatg ctcatgaata ccggtggaaa tgccggttcc 42061 cagtcatcgg cacttataat caggggcctg tccttgggag aaataagagc gagggatttt 42121 ttaaaggttt tatggaaaga aattcaggta agctgcattg taggagtagt tttagctgct 42181 gtgaattttg taagaatata ttattttgaa aaagcaggtt ttctagtgtc cgcaaccgta 42241 tgtctaacct tgttttttac gattatgttg gcgaaagtca tcggagggct gcttcccatc 42301 atggcaaaga aacttaaact tgaccctgcg attatggcag gtccgctgat aacaaccgtg 42361 gttgatgcgg taactcttac catatatttt accatagcaa cgtggttgtt ggacatataa 42421 aaagtgaagg atatattggt ctgacggcaa atttacataa aaaggagttg cctgttttgt 42481 aaggtcttcc tgaatctaaa agcaggaagg ccttataata taccggcgtt ttaataaaaa 42541 acactttatt atcctaaaat atggtatatg gacacggaat acaggctgtg atataataaa 42601 attgaaacgt atatttatta tatacattat atacgttcac ttcgaatatt gcatgtttgt 42661 ttgtcttgca tcatgtttgt aggcagtctg catgttaggt ttattctttg attagttttt 42721 ctcatgttaa agtggaattt caattttgcg cccaacagat gccgcccggt ttttaaagtg 42781 cctcattgac aaaataaggc tggttatact gttggttttt agaagattct aataatgtac 42841 agtattttat cgtaaatctt gaagttgatg tacttaaata gtaaaatgag aaatatatat 42901 ttactagtgt tttgcattta aaaaacaagg ggagaaaaca tattatgggc gataaaaaaa 42961 gagtactggt tatttttggc ggacaatcgt cggaacacga agtttcaaga atatcggcaa 43021 catccatact gaagaacatt aatttggata aattcgatgt ttcaatgata ggaatcacaa 43081 aagacggaaa gtggctttat tatgacgggc ctattgataa aattccttcc ggagagtggg 43141 aggaaatcgc actgaaagat gggacaagaa gtattgccga cagagtgagc ctgttcgaca 43201 acataataag ttgcaaaaat aacgcatgcg gccttgaaaa ggcctcagag aacgaaaaaa 43261 gcaaaaagat agatgtggtt tttccggttc tgcacggctg caacggtgaa gacgggacca 43321 tccagggact ttttgaactg gcgggcattc cttatgtggg ctgcggtgtg ctggcttcag 43381 cagtcggaat ggataagatt tatgcaaaga taatttttga aaaagccgga ataccccagg 43441 cggattatct gtatttcaca agaaaagaaa tttacgggga tgttgagggt gtggttgaca 43501 aaatagagga gaaattttca tatcctgtat ttgtaaaacc gtccaatgcc ggttcttccg 43561 taggtgtgtc aaaggcgcat gataaaaatg agcttaaaga ggcattgatt tatgccgcca 43621 ggtatgatag aaaagtactg attgaggaat ttatcaacgg aagagaagtt gagtgtgccg 43681 tgctggggaa tgatgatcct gtggcatcaa cggtgggaga aatcattccg ggaaatgaat 43741 tttacgacta caaggcaaaa tacattgaca atacttccaa aataaaaatt cccgcggatc 43801 ttccagaaga gaccgtggaa caaataagaa attatgcagt aaaggcattc aaggctttgg 43861 attgttcggg acttgcaaga gttgactttt ttgtgcacaa ggaaaccgga aaagtttata 43921 taaatgaaat taatacaatg ccgggattta caagtataag catgtatccc atgctttggg 43981 aggaatccgg catttcctat ccggaactta ttgaaaagct gattgacttg gctgttcaaa 44041 gatacaatga caatctcaaa gaatatgatg agtagaaaat atgatgagta aaataagaag 44101 ctatgtagtt tagtcgtatt acagttgggg gaaaatgcta tggacaacag gccaataggt 44161 gtttttgatt cggggctggg cggtcttacc gtgctgaagg agataaaaaa tttgttgcct 44221 cgggaaagta tagtatattt cggagacagc ggaagagccc cctatggttc caaatcaaaa 44281 gaaactgtgg taaaatatac ttttcaggac atccggtttc ttctgaacca ggatataaaa 44341 atgattgtaa tcgcgtgcaa tacggcaagc gcatgcagcc tggaccaggt gaaaaacagt 44401 tttgacattc cgatagttga ggttgtcggg ccgggagccg caactgccgt cagggaaacg 44461 gtaaacaaaa aagtcggagt gataggtacc gtggcgacgg tgagcagcgg ggtttacgaa 44521 aaagccattt taaagctgga cccggaaatt gaaatctatc agaaggcttg tcctctgttt 44581 gtgccactgg ttgaggaagg ctggtgggaa aatgacattg cgctgagaat tgcagaggaa 44641 tatcttttgc cgttaaaaga aaaaaacatt gacacgctgg ttttgggatg cacccactat 44701 ccccttttgt acaataccat ttcaaaggtg atgggagacg gtgttaaact ggtaagttcg 44761 gcattggaag tggcaaaagt ggtaaaggag atgatagaga agagcaatct taacagggat 44821 gaaaaattaa atcctgtgta caggtattat accagtgaca gtgtttacaa gtttgaatct 44881 ctgggcaatt ctattttaaa tcatgaaata tgttctgctg aaaaggttga tattgaaaga 44941 tattagattc gcaaatttcc ggtgggacga aaagtcttgc cggcaagaac ggaggcggga 45001 aaccgtgaat aaaaatgtta ttatttctgt aaaaggggtt cagacttcgg aaaacaatga 45061 caaaaatgta ctagaacttg ttacggaagg caaatattat aaaaagggaa atgcctatta 45121 tgtgacatac aaggaaagtg aagtgacggg catggaaggg acaaccacca cccttaaaat 45181 ttccgacggt gttgtaacgt tgatgaggtt tggtacggtc aatgcccagt tcattttcga 45241 agaaggacaa aaacatgttt cctattatga cacacagtat ggtacgttta caatgaaagt 45301 taccgcccgt tcggttttaa taaatgttga cgattcgggc ggagaaatta aggttgatta 45361 taaacttgaa atagatgata ataaaagtgg agaaaatgat tttcatatgt ttattagaga 45421 ggtaggacag ttagatgacg aatgtagtgg agactataaa aaaacaaatt aatgaagtgg 45481 ttaaaaattc aatatcaaag gccgttcaaa acggagaact tccgcaattt acggtggacg 45541 agctgtttat agaaattccg aaggaaaagg gacatggcga tttttcaacc aatattgcca 45601 tgcaggcggc aaaaacggta agaaaagcac ccagacaggt ggctgaaata attataaaaa 45661 atatggactt aagcaataca tacattgacc gggttgaagc ggcaggaccg ggatttatca 45721 atttcttcct tacaaatgca tggctgtatg acgttctgaa ggttatccag aaagaaaaag 45781 aaaattacgg aaatctggat atcggacgtg gccagaaagt catggttgag ttcgtcagcg 45841 ccaaccccac cgggcctttg cacatgggca atgccagagg cggagcgttg ggagattgta 45901 ttgccagtgt tcttgagaaa gccggatatg atgtgaccag ggagttttat atcaatgatg 45961 ccggaaacca gattgaaaaa ttcggcattt cgcttgaagc aaggtatatt cagcttttga 46021 agggagagga tgccgtagag ttcccggaag atggctacca tggcgaggat attattgacc 46081 atatgaaggc gtatattgaa gaaaacgggg acaatctgct ttacgttgac agtgaagaaa 46141 ggcgcaaaac ccttgttgaa tatgctttgc cgaaaaatat tgaacggata agaaaatccc 46201 tggaaaacta cggcgtggtc tttgatgtct ggttttctga gcagtccctg tatgacaacg 46261 gcgaagtccg ggagacattg gatattctca aagaaaaggg atataccttt gaaaaggacg 46321 gagctgtctg gtttaaagct tccgccctgg gagcggaaaa agatgaggta attgtgagga 46381 acaacggaat cccgacatat tttgcggccg acatagccta tcaccgcaac aaatttttaa 46441 agcgcaagtt tgacagggtt ataaacttgc tgggtgcgga ccaccacgga catgcggcaa 46501 gaatgaaatg tgctttaaaa gcctttgaca ttgacccgga caagcttgat attgtaatat 46561 tccagctggt gcgcctttac agaaacggcg agatagccag aatgtccaaa aggacgggca 46621 gggcaatatc cctggacgat cttttggagg aagtcggaag agatgccgca agattcttct 46681 ttaacacgaa agcttcagga agccacctgg actttgattt ggaccttgca gttaaaaaat 46741 caaacgaaaa tccggtatat tatgttcagt atgcttacgc ccgaagctgc agcatgctga 46801 gacttttaga gagcgagggc tttaaagtgc cggatgttga ctcggtcgac cttacagttt 46861 tgaaggcacc tgaggaaatt gagctgatga aaaagctttc cgaataccct gaagagataa 46921 gaatttcggc ccagactttg gagcccagca ggcttacaag atatgttctt gatgttgcat 46981 caaatttcca cagcttttac aatgcctgca gggtaaaagg cgaggaagag aatttaatgt 47041 atgcaagaat gatacttgtg gacagtacaa gacttgttat aaaaaatgtg ctggatgtgc 47101 tcagcataac ggctcctgaa aaaatgtaga agcaagtatg gaattgtttt gcaaagctcc 47161 ggccggataa ttatgataat aatttggccg gagtttgttt ttttacaata attttttata 47221 catctcattt taatttatta catttgttat gtacatgtac gttatgatat aattttttta 47281 taaacatgcg ttgcaatgga gaagctttat atggttgatt ctaaaaataa aaagtatata 47341 atcaaagttt taatcccata tcttattgta ttttatttct tttggtccgt gtataccata 47401 tttctcgaac cgtttataga aaagggtccg tatcttttaa atctgctcct ggtaaacttc 47461 gtaaaactgt gcttttggac ggtacccgcc ctggttgttt taaaatacgt tttcagggaa 47521 aaacccttaa gttatataaa gctcagcaaa gacaaacttc gcggctttgc atacggttct 47581 ttgtacggag ttgtcattgt catatatata agcgtcacca gatttttgtt cagcggtgaa 47641 ttcaacttta atcctttttt cggtttggag tcgtggatag gcggagtatt gcttatcgga 47701 tttaccgagg aaattgtatt tcgcggattt ttactgcaga aatttgaaga aattatggac 47761 agcaaatacg ccaatttgct gaccgctgta ctgtttcttt tgattcattt cccgaagtgg 47821 tatatgcagg ggaatttgtt tgtggcggaa tttatggtga attcagtgtt gtttatgctc 47881 cttttcagcg tccttatggc ggttctttta aagaaaacga actctttgtg gacctgtata 47941 ctcattcatt ccgccaataa ctttgcaatg tttgcattgg gtgaataaat tttgatataa 48001 tatttgaggt aaaatattct aatattctat atttcttgat tgctcacaac aagtatgctg 48061 caaggaggaa cggttatgaa aataaaatgg cttggtcatg catgtttctt gctgacatcg 48121 gataacggga taagagtggt taccgacccg tatgataata ccgtgggata caaggtggag 48181 aaaattgatg cggaaatagt gtctacaagt catgatcatt atgaccacaa ttatgttgac 48241 atggtttcag aaaatgcaaa gcatgttaag tcagaaggga aaacaaacat agacgggatt 48301 gaaataactg gtgtgacttc tttccatgat gactgcaaag gagcgaaacg gggaaaaaat 48361 gttattttca aattcaagat agatggaatt gacgtttgcc atttgggaga tttgggacat 48421 gttttaagtg acagccaggt cagggaaatc ggaaatgtgg atgtgctgct ggtaccggtg 48481 ggaggagttt atacaattga ttacaaagga gccgttgagg ttatgaaact tgtaaatcca 48541 aaaataacca tacctatgca ttacaagact ccggctctta gctttgacgt tgacggtgtg 48601 gaaaactttc tttccgcaac aggaggaaaa catatcggaa agcaggagat agagcttaaa 48661 aaagatgaaa ttgaaaactg gccgaaagtt gttgccctgg attatcagta agaataatta 48721 ccggaaagta aaatatattt taaagtgaaa tacgcttcat aaacgggatt ggaagttatc 48781 caaaacagaa tatcctgtaa taatttatta ataataaatg tcctaaaatt agccgatata 48841 aagaacggct aattttttta atttttaatg tttataactc cttgtgaatt cgaagacggt 48901 ggagtggtga atatggaaaa aaagttttca aataaacctg gaatcagaat ttgttttgtg 48961 atggtatttt catttgtact gtcttttgcc ttgaatattc ccgtacatgc cgatgaagag 49021 ccggaaaaga tatattacgg attgaagaat gcttccacaa ttcttaacaa tataaatttt 49081 accgatgtca gaaactctgc aacatggtca aaggaggcaa tttgcgaggc tgcggctttg 49141 gatattgtta aaggctacgg caacagggtg tttgggcgca caaacaatgt gacaaaggaa 49201 gaggcaattg ccatcatata cagggcggca ggaagggaaa aggatgcaca attggcggcg 49261 gaggcccttg agactgctag aaatgccgaa gacagaagca gttatgcccc aagcatgtgg 49321 tccgacgggt atctgcagct tgcagccggt gagggcctga ttagcagcca ggatcttcag 49381 gatgctttca ccgcggatca aagcagcctt gggacaggag catttttaag aagggcgccg 49441 gcccaaaggc aggaagtggc ctattggatt tcaaaagttt tcgacattga acctgtctac 49501 ggtcagcaga aaatattcaa cagttttcgg gactggtcga gcgcggatcc tttgaaaatt 49561 ccgtacatag aagcagttct tgtggaaaac ataatgaacg gtgaggggaa tggttatttc 49621 agacccacgg gttttgtaac cagggaacag attgcgcaaa taataaaaaa tgcggataaa 49681 agagttcttc cgcttttagg ctatgaaaag aaaatgggta cggtggaaga catccgcaag 49741 gaatacgatt ttacgggaaa tactcatgta tataccaata ctttccatat aagaagcagc 49801 aacggcaaac ttcacaagat tgtgaccgag ttttacgaca gcagcaggag cggatataga 49861 aatgagcagg gcggaagcag cataaaaccg tccgacaccg atcttattgt ttacagggac 49921 ggatggatag gcacaagctc ccttttgaaa gtcggagaca gagtagagta tataacggca 49981 gcggacggca cagtcagata tgtgcgggtg atatccgcca cgtcggatac ggaatacatt 50041 gttgcaaaaa taaaagaagt aaattatgac acttccacca taaaggcggc aatagggttt 50101 taccttgagt acccggacat tgacatggac agtataagtt ttgattttag aaacagcgac 50161 gggacagttg acgcaacact tgtatacagc aatattgtaa aagtgtttat agagggaagg 50221 atagcaggta taagggatat tgaacccgga acagatgcaa ttcttactgt aaaggacaat 50281 attataacta caattacgac ccttgactta agactgaaag agcagggtgt gataagtggt 50341 attgttgagg aaaacaatcc ccacctgggc tatataagtt tatacagtga taacggttta 50401 cgggtggacg attcccttaa caaaataaaa atatataact attccaatcc ggaggaagta 50461 acggtatata aaaatcacgt ccctgcaaaa cttgaagatg tcgaaagcgg tgattcggta 50521 tacattaaac ttgaccaaaa cggagcaata gaaatgataa gtgccgtgga caactatgtg 50581 gtaaagtacg ggaaaataat atctgtaagg ccggggctta taaatgttgc ctatgatgac 50641 ggcacgcagc aaattcttag tgttgacgaa aacgttccga ttgtgcagga caacaaactt 50701 atggattttg atgccctgaa ggatggagac agggtgaaac tgcttttaaa tatcacagac 50761 aaggctacaa ccctgaaaaa gcttaccgta gaaggagacg agcattttat tgcaaatatc 50821 taccggggta tagtggcatc ggtggatgat atttcgaaaa agctgttgct tcagcacctt 50881 gaagtgttta acaacggaga atgggaaaga acggaacaga aaggttttac ctcattgaaa 50941 atgtctgagg ataataaatt tgtttacaat gacgatattg tggacatgcg ccgggcaaag 51001 gagctgattg cgggaagcac agcgtatatt gcagttgaga aagactacgg cggaattgaa 51061 aaggcggttt ttgtatccgt taaaaactcc aaagacagtg aggctccggt gcttaacgac 51121 agcatcatgt cagccacttt cggaaataaa ggggaattca cgctgaaaaa agaatatctg 51181 aacatttctt acggaaacgg gacaatcatt gtaaaggaca acaggctggt taccggaaac 51241 agcataaatt cggaggacag ggcatatgtt gttgcaagca gaagctatga cgacggaaaa 51301 tattatgctt ttatagtcaa gatagatgac aagacggatt cgaacttctt taccatatat 51361 cgcggaagga tagcaaacat aaatgagaac aaagacttta ctttggaatc ttattcagag 51421 cttaaaggag ttgaatggaa ctactacaac acccccagaa cctttagaat cacatatgac 51481 acgcaaattc taggtgatga cggagttgta ggacagaggg actttaccga ctatggtgat 51541 tcaagctata agagcaggac ggtatatgta ttgtcacacg gtgccgatgc tgtgttgatt 51601 agtactgctc cttacggtaa cattaacgta aaaggtaaaa tttatgaact tatatcagaa 51661 aatgccgatg gttcagaggc tcaggaagga cagcaagaac cggtgggatt taaactccag 51721 aactcaaaag tttacgattt gcaatcgcat atgtgggtgg acggtaaaga catggatatt 51781 aaccttctta aaaacagcat tatacttaag gacaacaaaa ttataaaacc gtccgaatta 51841 aagaaaggcg acagtgtaag gcttatcaaa aaagatgacg aacaggctgg agatgcctat 51901 attatattcg ttgaataata tttccggctt ttggaggcga aacatatgat aaaaagaaag 51961 ttgtcattaa aaaggggatt ggcatttatc acggcaacat ttataattgt tcttgtaaca 52021 ggtgttttcc gtgtatatgc aagagaaggg gacagcggat acgaaggagg catctccagc 52081 ggggaagcac cgggaaagac atcgttcgag tataaagagg tgtgctttat aaccggtgaa 52141 cccatagtat ttgaaggaac tctgaccata agaaaaacgt tgaggcagga caaaacaaca 52201 ggaaaaaatg tgattacggc aaattacaca tacaacctca ggaatcttga aaaagacgcc 52261 acactgacaa gagttctgtc atataccaca actcttaccg aaaaggaaaa cggccaggta 52321 attgaagaaa cgggatttgg cggaagatgc accgaagtgg tgagaatcgg ttccaccact 52381 tacaccctgg aaaattatga ttttacaaag accaatataa aagacaaaaa accggcggtg 52441 gattattttg ccgggaatct gtgggggaaa aagacatacc ggaccggcac cggtgcaaac 52501 agcggggaag ttaccgttga aatatcggga gattattatg gatacaatca gatttgggga 52561 accgttgaag cccaggtttt aaattatgta atagaaagtc agaaaagaag cggtgaagta 52621 ctggaccgct ggggcggaac tgcaactgta agcatttcgt ccacaacaac caaaaaaatt 52681 gactatgttg aaaacaaacc ggatgttata agctttgaag gaggttttgt agagagtcag 52741 tacaacaaca gcatacttca gtatacggca aaacttcccg agtttgacca tcagggagta 52801 tccaccgaca gaatggttga gacaaaagga agccttatga ttgaaagctt tcccaccagc 52861 cgaagacttt tggtgccgga actgagtcac ctgagaggac attgggctga aaatgatatc 52921 aaggcgctgt acagcctgga aatcttcaaa gaaaatccgt ccggtttcaa cccccaggaa 52981 gtcatgacga gagccgagtt taccgaagcc attgtgctgg ccgcgggcga agttccgaaa 53041 gatccgctgc ttgttgagtc aagaaccacg aaaaagactt ccaataccaa agaagagata 53101 acttcccctt ttatcgacgt gccaacagga agcaaatatt ttgaaagcat aaacaatgcg 53161 tataaaaggg gaatgataag cggaagaggg gacggaactt ttgcaccgga tgattatctt 53221 accacggcgg atgccattac catattggta aaagctttag gtcttgaagg acttgctcct 53281 tcaaacggag cggtaacggt gttcagggac agcgacgaca taccgagata tgcgaaaggt 53341 ccggtttatg ttgcccatag aatcggtctt gtgatgggtg acgacaaggg ttatctgaga 53401 cccaacgagt atcttaccaa ggccagggcg gcggtaatta tcaataattt tattgactat 53461 atgagaaatg atttaagaaa ggattacagg gagagaatag taaattatta ataagtatat 53521 ttattaaaat taattaatat taaaattaat taagtgcttg taaatagcat caaggaaaag 53581 gggaatggat gtgacgggta aatcattaaa acggatactg ttatctttgg ctgttttttg 53641 tattttaata acgggcccgg gaattgcctg tgccgaggaa gccacgacgc aagaaaagga 53701 aattttgttt tccgactatt tcaaaagcat gatggacatg gcgcaagaca aatacaaagg 53761 tgaaataacc gaaaagcaaa tgctggaagg cgcgctgaaa ggcatattca gcacaatgga 53821 ttcttacacc gtctattaca ctgtggaaga gtcgcaagac ttttttaccg atataaacgg 53881 ctcttacacg ggaataggtg tggtaatgtc ggaagttgac ggtaaaatag tgatagacaa 53941 ggtgtatccg tcctcaccgg cggaggaagc agggataaaa aaaggcgatg ttatagccca 54001 ggttgacggt aaaagcgttg agaacctttc tttggaagaa gtggccgggc tcataaaggg 54061 accgtcgggt acgaaagttg taatcggtgt gttaagaaac ggaacagacg gggtaataga 54121 gctggaagtt acaagaaggc agataattat aaatcctgtc acccataaga tagaaggcga 54181 tataggttat ataaagctgg aatcgttcaa ttccaatgca agcaaggcta tggaagaagc 54241 cttgaaacaa atggataaaa acaatataaa aaagataatt cttgatttac gggacaatcc 54301 gggcggagat gtgggccagg cggtttcaat tgccaggaag tttgtaaaaa aaggccttat 54361 tacaaagctg gattttaaat cggaatccca aaaggatgaa gagtattatt cctatttgga 54421 ggaattaaaa tataaacttg tggtattggt gaacgaaaac agcgcaagcg cttcggaaat 54481 attggcggga gcgatacagg atacaggttc gggtattttg gttggtacaa caacctttgg 54541 aaagggaaaa gtccagaatc tttatcccat actgactccg gaggcggtgg aaaaatatcg 54601 gaaagaaacc ggagaaacat ttgtgaacgg atacgattta ttggaaaaac acggcatcta 54661 tccttccgat gaagaaataa tcggatgggt gaaaataaca accggggaat attatacccc 54721 caacggaagg atgatagacg gagtaggtct tgagcccgac gtttatgttg aaaatgaacc 54781 ggagggaaaa tataaaatcc ttgaaggtgt ggaaaaactt cgcaaggtga caaaaccttc 54841 tttaaatgct caaagtgagg atgtcctgaa tgcggaaaaa attttatcgg cactggggta 54901 tgatgttgac actccggaca atttaatgga tgaaaagacc gtcaaggcgg tggcagagtt 54961 tcagagagac tgcggattgt attcttacgg agttttggac tttgccacac agcaggcgct 55021 gaatgacaaa ttggatgaat tgcttcttgt aaagaacaga gacaaacagt atgaaaaggc 55081 ggtggaactg cttgaaaatt agtatgaatg cggaactatc gcaactacct taaacgagat 55141 atacagtttt attaactgta tggcaccctt tttgacagtc aaagataata caagaggcct 55201 gaagactgtt gtgttgagcg tttcaggcct cttttttatt caactaaatc aaatacgaaa 55261 ttttattatt gttattttgt ttgatttacg aatttatttt gaaaagcgag tgaaatttgg 55321 atacgggtca atacttttat aactccaatc ttgatttttt tccaaggaga taatattata 55381 ttaacaataa aaggatttta tagaattgtt tatcgtgaaa aataatccca aaccgaaaaa 55441 tcccggtaat atctgtatag ttacccaaaa cggcaggcga taaaatggca actataacgt 55501 tatatgccgg gaaaatcaac caaatgcccg gattgataaa a //