LOCUS NZ_ACVX01000039 30211 bp DNA linear CON 10-NOV-2010 DEFINITION Clostridium thermocellum DSM 2360 ctg00042, whole genome shotgun sequence. ACCESSION NZ_ACVX01000039 NZ_ACVX00000000 VERSION NZ_ACVX01000039.1 GI:256005746 KEYWORDS WGS. SOURCE Clostridium thermocellum DSM 2360 ORGANISM Clostridium thermocellum DSM 2360 Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium. COMMENT PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from ACVX01000039. FEATURES Location/Qualifiers source 1..30211 /organism="Clostridium thermocellum DSM 2360" /mol_type="genomic DNA" /strain="DSM 2360" /isolation_source="contaminant of Clostridium thermocellum strain LQ8" /db_xref="taxon:572545" gene complement(32..1939) /locus_tag="ClothDRAFT_2562" CDS complement(32..1939) /locus_tag="ClothDRAFT_2562" /EC_number="6.1.1.3" /inference="protein motif:TFAM:TIGR00418" /note="KEGG: gme:Gmet_1411 threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase; TIGRFAM: threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); TGS domain protein; Anticodon-binding domain protein; Threonyl/alanyl tRNA synthetase SAD" /codon_start=1 /transl_table=11 /product="threonyl-tRNA synthetase" /protein_id="ZP_05430701.1" /db_xref="GI:256005747" /db_xref="InterPro:IPR002314" /db_xref="InterPro:IPR002320" /db_xref="InterPro:IPR004095" /db_xref="InterPro:IPR004154" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR012947" /translation="MIKITLKDGSVREYNEGITIKEVAESISAGLARVALAGEVNGEV KDLSYPLENDCTLNLLTFDDEGGRDAYRHTTSHILAQAVKRLYPDAKLAIGPAIENGF YYDFDVEKPFSVEDLEKIEEEMKKIIKEDYKLERFTLPREEAIKFMEERNEPYKVELI RDLPEGETISFYKQGDFVDLCAGPHIESTGKVKAFKLMSVAGAYWRGNEKNKMLQRIY GTSFTKKSDLDAYITRIEEAKKRDHRKLGRELDLFDIYEEGPGFPFFMPKGMVLRNVL EEYWREEHRKAGYQEIKTPIILNEELWHRSGHWDHYKENMYFTKIDEADFAIKPMNCP GGMLVYKRKLHSYRDLPQRLAELGLVHRHELSGVLHGLMRVRCFTQDDAHIFMTPDQI ESEILGVISLIDDFYKVFGFKYHVELSTRPENSMGSDEDWERATNALKNALEKKGIDY KINEGDGAFYGPKIDFHLEDSIGRTWQCGTIQLDFQMPERFDLTYIGPDGEKHRPVMI HRVVFGSIERFIAILTEHYAGAFPVWLSPVQVKILPILEKQHDYVAEVKKALEEKGVR VEADLRNEKIGYKIREAQLEKVPYMLVIGDKEMENRTVAVRSRKDGDLGPMRLEDFVN RIVEAIKNKEN" misc_feature complement(35..1939) /locus_tag="ClothDRAFT_2562" /note="threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413" /db_xref="CDD:179011" misc_feature complement(1754..1936) /locus_tag="ClothDRAFT_2562" /note="TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase...; Region: TGS_ThrRS_N; cd01667" /db_xref="CDD:133437" misc_feature complement(1286..1435) /locus_tag="ClothDRAFT_2562" /note="Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469" /db_xref="CDD:158351" misc_feature complement(329..1216) /locus_tag="ClothDRAFT_2562" /note="Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771" /db_xref="CDD:29816" misc_feature complement(order(386..388,395..400,494..496,506..511, 518..520,800..802,806..808,815..823,836..844,848..850, 854..856,950..952,992..997,1004..1006,1016..1018, 1166..1168,1205..1207)) /locus_tag="ClothDRAFT_2562" /note="active site" /db_xref="CDD:29816" misc_feature complement(order(446..448,452..454,599..607,728..730, 809..814,842..844,851..853,857..859,896..904,908..916, 923..928,962..964,968..979,983..991,1043..1045,1049..1057, 1061..1063,1067..1072,1082..1087,1130..1132,1139..1141, 1145..1150,1154..1156,1160..1162,1166..1171,1175..1177, 1193..1195)) /locus_tag="ClothDRAFT_2562" /note="dimer interface; other site" /db_xref="CDD:29816" misc_feature complement(1049..1072) /locus_tag="ClothDRAFT_2562" /note="motif 1; other site" /db_xref="CDD:29816" misc_feature complement(848..859) /locus_tag="ClothDRAFT_2562" /note="motif 2; other site" /db_xref="CDD:29816" misc_feature complement(386..400) /locus_tag="ClothDRAFT_2562" /note="motif 3; other site" /db_xref="CDD:29816" misc_feature complement(59..331) /locus_tag="ClothDRAFT_2562" /note="ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860" /db_xref="CDD:29800" misc_feature complement(order(119..121,125..127,155..157,179..181, 197..199,302..307)) /locus_tag="ClothDRAFT_2562" /note="anticodon binding site; other site" /db_xref="CDD:29800" gene complement(2746..3363) /locus_tag="ClothDRAFT_2563" CDS complement(2746..3363) /locus_tag="ClothDRAFT_2563" /inference="protein motif:COG:COG5401" /note="KEGG: dal:Dalk_3055 hypothetical protein" /codon_start=1 /transl_table=11 /product="Spore germination protein-like protein" /protein_id="ZP_05430702.1" /db_xref="GI:256005748" /translation="MKRILTLIAALTILVFAAGCSLSGGTGTGQAGNEQQQQSDEGNG SEIQEPDLEKESEKGSEEEPEEEETLTVMVYFGDFQSEKVAPETRTVKVKAGDSIEKV VFEELAKGPETEGLDPVIPEGTKLLSVRTENGICTVNLSKEFVENHIGGSTAELMTIN SIVASLTELPGIDKVQFLIEGNVREVFIHEALDTPIKRNESFIKK" sig_peptide complement(3268..3363) /locus_tag="ClothDRAFT_2563" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.578 at residue 32" misc_feature complement(2803..3150) /locus_tag="ClothDRAFT_2563" /note="Sporulation and spore germination; Region: Germane; pfam10646" /db_xref="CDD:151159" gene complement(3522..4412) /locus_tag="ClothDRAFT_2564" CDS complement(3522..4412) /locus_tag="ClothDRAFT_2564" /inference="protein motif:TFAM:TIGR00426" /note="KEGG: pat:Patl_3198 helix-hairpin-helix repeat-containing competence protein ComEA; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1" /codon_start=1 /transl_table=11 /product="competence protein ComEA helix-hairpin-helix repeat protein" /protein_id="ZP_05430703.1" /db_xref="GI:256005749" /db_xref="InterPro:IPR000445" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR004509" /translation="MLRDFFNQEVSMKKGIVGLMILGLIVTTSVTGFLLANDGEDIII SKAKAGQYTVEAENGEEKTTEKLVQEKEEAADEIKVYVVGEVNKPGVVTLKKGQIIQD AIELAGGPTEDADIENINLAYELRENVMIRVMSKSETTGQDIGEEGDMQVAAGNTENK STAAGSNSTKNSQSKNVSGGTSKNSSGSNDAKSNSGKSTNNGGVSGIAVTKDSGGAVV GENASSSENSKTANSKININTATVEELDSLPGIGPAIAAKIVAYREQNGKFKSIEDIM NVSGIGQSKFNNIKDFITVN" sig_peptide complement(4302..4412) /locus_tag="ClothDRAFT_2564" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.863) with cleavage site probability 0.842 at residue 37" misc_feature complement(<4071..4178) /locus_tag="ClothDRAFT_2564" /note="endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl11430" /db_xref="CDD:187036" misc_feature complement(3528..>3773) /locus_tag="ClothDRAFT_2564" /note="endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl11430" /db_xref="CDD:187036" gene 4691..5989 /locus_tag="ClothDRAFT_2565" CDS 4691..5989 /locus_tag="ClothDRAFT_2565" /inference="protein motif:PFAM:PF00768" /note="PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: ppg:PputGB1_4856 serine-type D-Ala-D-Ala carboxypeptidase" /codon_start=1 /transl_table=11 /product="peptidase S11 D-alanyl-D-alanine carboxypeptidase 1" /protein_id="ZP_05430704.1" /db_xref="GI:256005750" /db_xref="InterPro:IPR001967" /db_xref="InterPro:IPR012907" /translation="MKRLLLLLIMTIILFSNIVTLKAQPLDINAQAYILIDSKTGQVL AEHNPDLRTYPASTTKIMTAILALELGDLNQIMTVSQSAIDDIGPGGMHIGLLPGEQL ELRYLLDALLVRSANETAYVIAENLCSSREEFYRLMNEKARELGATNTNFVNPCGIDN GEKGKNHLTTARDLAKIAQYAMTIPEFREIVQKTIIKIPPTNKHAEEVIVGTTNKLLL YSNSKYKSEHYTKITGIKTGYTDRALNNLVSSAVNDEGTELIAVVLGVENYDMVFEYS KMLLEYGFKNYSVQPVIAPNSYITSVPVLKAAGNHNLDILASPEGLKCLLPNNSTKND YEIEQHILENIEAPVKKGDVLGYIEVKKDGVTIGKIDAVASRDVEKLEPPVEPQNIII KTANDPILKKVTTGALIFLLMFLMLRFTLRRISRSLHSKR" sig_peptide 4691..4762 /locus_tag="ClothDRAFT_2565" /note="Signal predicted by SignalP 3.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.652 at residue 24" misc_feature 4745..>5434 /locus_tag="ClothDRAFT_2565" /note="Beta-lactamase; Region: Beta-lactamase; cl01009" /db_xref="CDD:186300" misc_feature 4757..5494 /locus_tag="ClothDRAFT_2565" /note="D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768" /db_xref="CDD:144388" misc_feature 5549..5830 /locus_tag="ClothDRAFT_2565" /note="Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943" /db_xref="CDD:149169" gene 6255..7985 /locus_tag="ClothDRAFT_2566" CDS 6255..7985 /locus_tag="ClothDRAFT_2566" /inference="protein motif:PFAM:PF00501" /note="PFAM: AMP-dependent synthetase and ligase; KEGG: ppd:Ppro_3483 AMP-dependent synthetase and ligase" /codon_start=1 /transl_table=11 /product="AMP-dependent synthetase and ligase" /protein_id="ZP_05430705.1" /db_xref="GI:256005751" /db_xref="InterPro:IPR000873" /translation="MKTSPVFEVRTIKNLRDMIEQSSKLFANKDAFRVKTKDNSYRGI TFAEFKNDIDAFGTALLDLLGTEKGFVAVIGENRYEWCVTYLATINGVGVVIPLDKEL PLPELENLLKQSNANAIVYSGKFHDAIKEMSSRLSNIKYFINMNTNEHEDDKFLSFWV LLEKGKKLLESGKKDYLNAPIDENAMSAMIFTSGTTGQAKAVMLSHKNICSNMMAVSA SVYMDSTDSVLSILPLHHTYECTAGFLTMIYNGATITFNEGLKYIGKNLKEAQPTILI LVPLILESMYNKIWEQASKDKSLKFKLKAGLFISNLLYKVFKIDIRRKLFKSVIDNVG GKLRLVISGAAALDPEVAKGFEAMGIKVLQGYGLTEASPIVAVNRDKSYRHDSVGLPL PGLDVEIINPDKEGFGEIIVKGDSVMLGYYNNDDATKAVLKDGWLYTGDLGRMDEKGF IYITGRKKNIIVTKTGKNIFPEEVEAYLNKSPYIKESLVSGRENDKNDETIVVAQIVP DMDAIKAKLKTDTDPSPEEVYKLIKAEIRAINKNMPVYKRVVDITIRENEFAKTSSKK IKRYLEKTNV" misc_feature 6255..7970 /locus_tag="ClothDRAFT_2566" /note="Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022" /db_xref="CDD:31225" misc_feature <6777..7652 /locus_tag="ClothDRAFT_2566" /note="Acyl-protein synthetase, LuxE; Region: LuxE; cl10450" /db_xref="CDD:186997" gene 8400..8843 /locus_tag="ClothDRAFT_2567" CDS 8400..8843 /locus_tag="ClothDRAFT_2567" /inference="ab initio prediction:Prodigal:1.4" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="ZP_05430706.1" /db_xref="GI:256005752" /translation="MNSKDIIAKSRTESDIFALKCMKFCFIFAIIDFFIVELNKQWKA DAGDWLIAVSGIAALIPIFYYKFSKEKQNFVAVLLISAELISIGLYISSWVYAAPALI FPFVIGALHYDSKIFKKLMLIKIPALIVMSLFCTSCTTEHLCWMT" gene 8938..9708 /locus_tag="ClothDRAFT_2568" CDS 8938..9708 /locus_tag="ClothDRAFT_2568" /inference="protein motif:PFAM:PF00015" /note="PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: cff:CFF8240_1223 methyl-accepting chemotaxis protein" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis sensory transducer" /protein_id="ZP_05430707.1" /db_xref="GI:256005753" /db_xref="InterPro:IPR004089" /translation="MAGKAEGSQDYIREIETHIDKTLEHSDIITKLTESMSEITEKNQ NNIECIVENVNKINTSNQQTIEEFEYIRQNNELINEALQVINSVSEQTNLLALNASIE AARAGEAGKRFPVVAMEIRKLADQSNASAQNITDILNKMGEGTNQSLKAINLTQTNIF DTLELLENTEKDFSQMYNCQNSVINEIIQSEKLIKKLEDDIQAIKSVMGQTLSEFEAT SSEISDISNVLEELNKSFQAISDFAEDVQTSSNRLIEK" misc_feature 8938..9669 /locus_tag="ClothDRAFT_2568" /note="Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283" /db_xref="CDD:128579" misc_feature 9046..9615 /locus_tag="ClothDRAFT_2568" /note="Taxis toward Aspartate and Related amino acids and Homologs (TarH). The Tar chemoreceptor of Escherichia coli mediates attractant responses to aspartate, maltose, and phenol, repellent responses to Ni2+ and Co2+, and thermoresponses. These...; Region: TarH; cl00144" /db_xref="CDD:153541" gene complement(9790..>30211) /locus_tag="ClothDRAFT_2569" CDS complement(9790..>30211) /locus_tag="ClothDRAFT_2569" /inference="protein motif:PFAM:PF00801" /note="PFAM: PKD domain containing protein; Hyalin; S-layer domain protein; Fibronectin type III domain protein; Cna B domain protein; APHP domain protein; SMART: PKD domain containing protein; Fibronectin type III domain protein; KEGG: afw:Anae109_4253 fibronectin type III domain-containing protein" /codon_start=2 /transl_table=11 /product="PKD domain containing protein" /protein_id="ZP_05430708.1" /db_xref="GI:256005754" /db_xref="InterPro:IPR000601" /db_xref="InterPro:IPR001119" /db_xref="InterPro:IPR003410" /db_xref="InterPro:IPR003961" /db_xref="InterPro:IPR008454" /db_xref="InterPro:IPR011635" /translation="EDGVEFNQPLNANTFIDNGCVIKFPGEQKRGWKLSADEEYTGNL YIGAGVLDLNGFNLTVNGDLIQSGGVIDLNGGCLTVKGDYRIQTEIPSSNGQTINMYS NGYLKMTKPTDYLKVEGDFLIYSQHSHANYLTDGTLEVKGNFTQKRYNSYDNFKATGN HRVVLSGEELQIVTFESSSGSGSCINILEITNSSDKGVRFTSKVFVNGALKYTSTPVA GGEYLCIGTNTAINWDTWDYDLCIDGNRTLVRDINIKGSLFLNDGILNLNGYKLSVGG NLIQSGGTMYINKGQLLVEGSYRIQSRNYQADGTFEYGRCYGYLRMNNEEDYVRVGRD FVTQSYYSHASYLTAGILEVKGDFTQKGDSSSSSNFRATGTHKTILSGESLQRVTFTH PGDSGFNELIITKPLESGYIFSHSPLWNIIKEEVIDSEPPSVPTNLQVVSKTLTTVTL QWDTSEDNVNVEGYEIYRNGIRVGNSRTLSYIDHGLVPNTEYTYTVRAYDAVRNLSDF SEAVKVRTDVDNEPPTAPKNLGISSRTDTSVTLTWSASTDNAAVTGYKIYRNGVNIAD TVNTRYTDYDLEPGTYSYYVKAFDASGNVSDVSNTVVFDNQPPTAPENVFVTSVTTTS VSLEWTESTDNIGVAGYRIYRNGVHIRNVTGNKFTDTGLTPDETYIYIIRAYDNAGNV SPESESITVVAASDAEPPSAPSNLRVVSKSESSITLTWDKSTDNVKVAGYKIYRDGIE VGTSDTNLFIDKKVTKDHSYTYSVKAYDMAGNYSAESQPLTVTLVLPAAPVQIEAVAG EGKIDVVWSKVDDSDIVKYRLYRSENGHDYELIYESALMSYTDSNVLYGNTYIYMVKA VDIYGNESSGSTSQAVEPLPDITPPVIVGMVPADGSRVNGETRLSVLASDNVKIKAME FLFTSNKEEGTWESIGATTTGSVNWNTKELVDGLYYVKVVVSDTSDNISEFISEYTVD NTPPAAPVLKASSSELRVLLEWELSVKAEDFDHFRVYRSTEGGAEDTFELIENTMDFS YADTAAPLDVDSFYKVTAVDMLGNESEASNIVSARPGSDTTPPQIIKFTPEDGSSIRS GVTLTAYAKDNLEVNMYSFQFRPLDENGNPIGDGEWTPIADVQNPGKNEVQVKWDTLA TGPEGEELYPDGYYQVRVMVSDAAGNFSQKIHTYLLANDPPSPPEHLYVQAGEWQLVV SWSPVLRPDFRYYVLYRKEGREGTWEKIVSNTTSNVYIDTMRDPQKEYFYAVSVVNDL GRESERTYDYSKDENISEGIDIRALHQTSSPLIFSMKPAELSRTNSTLEIETVISDAV GVSVIYEYAYLGDSPSSGVDGDETWHLIGEDSSPVPGKVYDLEDFLERILKGEELPEI GVGENYFVSNCIWNVSSLASGTYAVRATAVNKGNKEASLIKKYIVDREAPQTPSGLKV VDPKVGGELQLSWERSKSDDVDHYVVYRATESGGNFKAVTRTKSLVYTDKGLEDGKIY YYVVTAVDSAGNESGKSNQVSSVPSALSDLTIVSVEANPQVPAYDRQAEIICTVKNLG YAKAEGRVDFYIENQGEWSKIGSSTIEVKSMDNSKASITWIPDSHLDNIVTVMAVVNT MDGSEDINEDNNSLTAELRLNIPPEAHIQTKEWIYSGDVFTLDGSLSKDSDGRIVSYK WDLENGVEKKGAHITHTYQIPGIYNITLTVTDNNGANSTATVSIHVYDNRPDLIVSDI QWDPEEPQEGDIVNIVAKIANVGKGPNRQGFLTGFYIDNKYMGYVRVDESINPGESID VPFTWKAEPGVHVLKVAANDILDNLKEISVENNTKTVALTTQQVNFPDVVADEITWTC GDNVKIDSESPFGYKVKISNIGTKKAEKFFVSLYVDGEWTAKQHINVLEAGETRELTF IVKPKSGKHEVTVKVDDPVPVLVELNNDNNVISVTTPEFNVTYPKIELSPVTWLPEES ILTEGTSLTFETKVKNTGTVDIRNKFDIDFVVDNVKIKTVTVEGLNAGEEKTVWARWM AQPGTHNVSVVADASGTVTDSVYGVQVSAVVPYIKILYPDLNISDVQWSPLSVKYGQP VTFIARVSNQSVTSIFKEFSVGLYINGKLSDEKKIKGLRGHSTAVVDLTCTPEVLGNA DVKIVVDPYNQIKQEPASDKVIRIWEGNLNIADALVAEIRPSPQEQNDEFMAHIYCTT DNFIPLEVKAKRASDLSKLIGPNEGIRAYYILRKDDTTLLNGEIGFDYASSVFKGQIP LMRLASGNYILTIEVGDGIESITSTSNIMIVEETVATVETDKKEYQHGETVHISGYFR YRDGTPLANQRIVLDLCLEPRLPDPIISYINGKMIIKAWHAETLRFVNTDENGYFEYD FLPTTLGAGKWRVNAFAYEKGVGSAAVSEFTVWGMTASPSTLSVVSSKNSSFSAFVSV NNMAKAEQSLTGVSAVLVDLTPDSGVRAVMDTSTLSSVIGPNGKSGVMLNFNAPLNAA DTAEYQVIFSSSEGAVATANVKVYLRPAIPNPVTDPKGVKVGVNPGKIVTKRVTVTNK GLGEMENIKLLPPANLPWVKAINLEKTFLAPGESTSFDIVVNPPEGTPLGQYQDSITV TDGKYKALVTVGVEISSANIGSLTFLVKDDMGQRVENAEVTIVGKEPYVQIIKGQKTT YYQNFYGRTDSNGIVTFEDVPIGEYTYTIRAKAKKHVTGTANVMPMHESAMVEVTMET EPVQIEWSVVPTTIEDKYDIQLDLTFETNIPSPKFGFVPPWLTVPKQVTEPIIIEATV INTGLVAVTDVTASVLRENNEDTGISIVGGGYIGEIPAHGSVRVSIMVKPGYYNLKYG INDKTGLPYNAIVLRGKYVSFDSDTGLPVFHANQVTGMLPLQNPGDKNAVLKVKTGEG EEKMEVNLANEQLVEFDYFVPIEDDNIDYGDGAAGNTQIASFKLSQTATLERQAFDAT LKIENGYIKDALQNLEVRILITDTEGNNITGQNFIILTSLNGISALDGSASLSAGEQV TATWQLIPGDGLGGEDPEGQTYLARAIVSYYVNGRYVETETEPQEITIKPQPKIKLTY YVPGKILSGQPFRLGVVAENVGYGTAKNLVIESGQLEIKTNQSGLLTQFEIVDTSFGS KTGNSFRLNLGDIEPQGRVSGYWLVRWIMYEEEERAKPFEGEFRDFKATLTHRDYNGV QLNPLIVSVDTEIIGKDNIYGDKSGTDGVLSLIDVGNTGFPNYLINLDTGMKFPIYVP ETLNVERQPDDENKILKFTVPAIEENPDAPEMPKYQVLMLKDPMPDTPISSVTREMDA EGTEPVALGKNNVWKNNGNIYIVDEIPVLSIKPRDYNNEQSRYYHPSTYTIDFTSGAV ISAVEYARIYYDVNPKTLEVEEKYAYYDIGVYPNEGQMTRVRAAVYNEGRSVEGGIVE FFATKLDFKGEVEEEIKIGEGRFNNLEPMNSTYVYVNWLPEKGGEYVLKAKIAGNGSP QAVSEAKARVNFKPFADAGADFSVDVLKPTKFDASRSFDKDGYIQSFIWDFGDGESAF GVAPVHTYLNSGTYKVKLTVIDDNYVEATTEMQVTVNETRADLRVTDISLSNDNPKEG ERVKVTATIFNGGYAATDNSFLVGFYVNNMFKDYVRVTESINPGESKDVTFEWLNIAG NHMITVVANDMGRLVDEADFDNNQLSRAVNTENAFFPNLKVTEFTWNGPEDGILDWNQ EITLSAVIENDGMANAEKFNVSFMVNDKLIEAKVIDGLPYSKGRNTVKVSAVWKVNTE GVQTFKVVADGPIPHIVEIERGDNEAVMQSPNIRLRYPDLTVQNVSIEPADMVIQPGQ PLVIDVSVANVGYADANKPFNVSVFADDVYIGTKEINEILKGTTSSAIFVWNRPVGGT KSIKVYVDENNSIREYNEGNNRFVYDLNIPLNVKLPKLSVEEIKTIPDDGTSKFGDTV VTQVRLKNIGDAAINKPFTTSLYVNNVLAGSFSTSTVLEPGAVVTGEIEWTADYLPTA PYYELVVFADAYSDIPMADREAAIKTAYYKVNDELRLELEETREVYTVKEDIEYFLKV TSTDELWRPLGTEDGISAELKLFKGQSAENDNPAGSPVFASLMEYDKVKGLFKTRIDR GLEAGDYIVQIIVNDGVERRNTVYSAFKLVPDYTVTVESEKQTYSVNEAIRINGKVTM GDGVTPIENAEVTIIIVGEEEWRTDTKTDKNGCYTGEFDLPEGFGGSYSLRAEAKVNG AVKSSSTKVFYVEGLYVSLPQKLEITAGYEQSAKITLVNVGTIPLTAINIDKIWEESS DYVIAEFEGHLPETVEPGESVDLNMVVKAGEEAVTGIYTLKLVVGCNEGYTYTSGIEV RVVEAKPEYYIEITGLKPSVTKSNVSSGAIEGAVRPGEMITQIISVYNVGTGSIKDLH VTPPEKLPWITLTTSGTDLILPMGKGLSIRDENARAIIAVNILPNEYVRPGIYEDVIT LTSNAGTKTIPVKINVGAAHVGTITLEAVDSNYAPVEDAKITLIGPHTSDWEQPMDEK VYQGVVTGKGVFRFENIPAGIYTLKVSASGYESVEESIIVPAVINEIPQKVVIEKKKI NLGWSSSSIMNSIRKGLRSTEEIVLEQQINTVPGKPQLVANFPGDEVTVRDTDLINGS VGGEFRIKNYSSEREIYWVEAEINYDNLDLPAYSVNLSYGKITNNSVALGDFGPGESK NIRWSFDLSCLYYEADVIPTDTPDQYKVIAPKEVTPENFDAWLKGLSWLYYGNRVVKK ISWDEETNTYIIGVPQNEDGSYTMPKGYIQRLFGKSYALDLTISISGTGLGLNGEEIE VSLNLPVRITYYPSDIIANPIPENDLKKFGVKEVSGNDEDGEVRKYSRNFLKERCNMD VSDLPEPAGNAAASFGFSQDVAMVDEAFNAEFVFYNPYEDKKIDDVRFKIIITDKPLD TMGNIADGGRSVTERFIIEADDIGNAMSNGEWMIVDKIGPDSNYSFRYNIKSRAGLGD ISGDYYAYVVYYYVLDGKVYQGYIGPKKFTIEPPPKLYISYKLNKIGESHYEIEAIVT NTGDGTARNVTVGLPVIPGAGKIEVIRIVSGDGFFQRDLSVLNIGNVYAGETKSGTFE IVANGLEDWMNLPSLAVHSTQVNDNIVVSPMAIQKVWRGDFELLIQEVERLEYNLQNL MNKTVHDLATVVVDVAEYVGEADEAERFSRAIDGMSAVISYVDFMVNLFDIFKVAFGL DNEIPLNPFPSKLYYTPEEQKLLQQIGAQLREIKKEIEEAKRKLEAGDMTEEEKLALE EKIKDLEAEYEYNVERMQAIIGWPTSAGEIILERFGLNGVVELISWTDDLMQYKVNQE ETRKMMGELVRFAYDLLAEGISREEAIDKVIERINAKAFRLVDRKKVEDFYVNSPELD DGQMDAMIQELIDKAEQLTIKELKSRVALELMEAKQLLDSYSYGRTNVPSYYPLDPLL EYLKGLNKELEGMWSIGDGEMAQGVGMYKNVWVYHPYYGDLIPYQVKIGEYKEPLVES LKIQSRGYSNLAARWEVNGIKAMLPAYDYFNLVIGFLPLSPYFGLMSSLFIDSMLMAS LKSQISLREIDLRYEQRKIFEDMISNTISTTAMAGTTLSRELSVANSVNGMFVAIDEW RKIDPPLPVEVMSMVVPDIAVGPANEVGVGKAVLKIKNLYTGALTISPSLEVYSSAGL VAVPDTNSVTVAPGETVTVEIPFSIPRSTMMDAGGYVAVAFFGVAEPGTMSIGDVKGP YTSYFFVGTQEQIEARRAYYKPSQPLGRDIEPGEQDEMFIESDGNLGEIRLFMAAKWG TTLEFAVYDPEGNVAGNVEGVVRNEIQGAEINGLINSVDYIRIVNPVKGKYRVVVKAP DGEESESYSLNMLELPDLGAVPDVSYPYVVVSTTKEVGFEFDVFESSMRYDIDKVSFS VGELRNEDGYVVPSGIFKFTGYDGKTLVETVEAGMGVTAIATAELPEDTPDGTYVGLF TVTVEGRNLNPALVRQTGTMSVSDSVYGWSEGFVSDIEGLEGYTYNVPIIIVLNTSIP QTPVLYPVSEPTEEAPYTVKIEGEAESESGIMIWVDGTLQGMLKANSEGLFSTSLGLN AGSHEIYVTAFNKYGTQSEPSEEYTVKIKGRYTQTPTAPTDLEAVYVGKERIELKWTP STGSLRGYKVYRDGKQIGEVTTPAFIDTDITEGEIYIYAVTAVDIFGEESGQSNLVTV TVEKKEKPVLIVPTDIVAEATGQRTKVDIGTAYVENMPDADVSNNAPEDYPLGVTTVV WTVKDKEGNVIVSGEQKVTVVDTTPPELMVPMDTTVETTEEKVSVVLGEASAYDLVDG VVDVTNDAPDLYPVGTTIVTFTAVDSQGNKVSKTVKVTVIKVEKPTEPPVEPPVNPPI EPPVNPPVNPPADNPSAGPVISEPVEVIPGPGGDKESDDEEKVQMDKEGNITVVPQTE GNAAISTVAARDLENAFEKFGSDPAGRKKVSIEIKKADGVEVYEQKLPSSIFTDTESG RKIEIKTPVATVEIPLDMFEEKDIEKAESISVRVSKVEASDLSMEQKAQIGDRPVIQL EVLVDGRLINWRSNKTSIKISVDYTPKGDELKKTDRIFVWYVGDSGKLSAIPMAVYKE DAGKVIFSVQQSGKYAVAYRYKSFDDLKGYDWAKEQIEILASKGIINGTSSTKYSPGL NITRADAVILIVKALGLEAEFTENFDDVSADKYYYEAVGIARSFGIVTGVGNNKFNPE TPITRQELMVIVNRALKVVGINLDTGDVSELEAFKDFSEISPYAVESVAALVKAGIIK GDDNKLIAPLRNITRAETAVIIYKLFEKMTELLQ" misc_feature complement(28663..28917) /locus_tag="ClothDRAFT_2569" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:28945" misc_feature complement(order(28699..28701,28747..28749,28915..28917)) /locus_tag="ClothDRAFT_2569" /note="Interdomain contacts; other site" /db_xref="CDD:28945" misc_feature complement(order(28684..28689,28693..28698)) /locus_tag="ClothDRAFT_2569" /note="Cytokine receptor motif; other site" /db_xref="CDD:28945" misc_feature complement(28429..28638) /locus_tag="ClothDRAFT_2569" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065" /db_xref="CDD:153489" misc_feature complement(27619..>28299) /locus_tag="ClothDRAFT_2569" /note="Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401" /db_xref="CDD:33208" misc_feature complement(27019..>27696) /locus_tag="ClothDRAFT_2569" /note="Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401" /db_xref="CDD:33208" misc_feature complement(25696..25929) /locus_tag="ClothDRAFT_2569" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065" /db_xref="CDD:153489" misc_feature complement(25069..25278) /locus_tag="ClothDRAFT_2569" /note="polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146" /db_xref="CDD:29065" misc_feature complement(24748..25056) /locus_tag="ClothDRAFT_2569" /note="CARDB; Region: CARDB; pfam07705" /db_xref="CDD:149004" misc_feature complement(24409..>24645) /locus_tag="ClothDRAFT_2569" /note="CARDB; Region: CARDB; pfam07705" /db_xref="CDD:149004" misc_feature complement(24100..24360) /locus_tag="ClothDRAFT_2569" /note="CARDB; Region: CARDB; pfam07705" /db_xref="CDD:149004" misc_feature complement(23776..24048) /locus_tag="ClothDRAFT_2569" /note="CARDB; Region: CARDB; pfam07705" /db_xref="CDD:149004" misc_feature complement(19531..19773) /locus_tag="ClothDRAFT_2569" /note="polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146" /db_xref="CDD:29065" misc_feature complement(19210..19518) /locus_tag="ClothDRAFT_2569" /note="CARDB; Region: CARDB; pfam07705" /db_xref="CDD:149004" misc_feature complement(18868..19185) /locus_tag="ClothDRAFT_2569" /note="CARDB; Region: CARDB; pfam07705" /db_xref="CDD:149004" misc_feature complement(18523..18831) /locus_tag="ClothDRAFT_2569" /note="CARDB; Region: CARDB; pfam07705" /db_xref="CDD:149004" misc_feature complement(17263..>17703) /locus_tag="ClothDRAFT_2569" /note="Predicted membrane protein [Function unknown]; Region: COG1470" /db_xref="CDD:31659" misc_feature complement(10219..10350) /locus_tag="ClothDRAFT_2569" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature complement(10042..10173) /locus_tag="ClothDRAFT_2569" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" misc_feature complement(9838..9972) /locus_tag="ClothDRAFT_2569" /note="S-layer homology domain; Region: SLH; pfam00395" /db_xref="CDD:144111" ORIGIN 1 ttgttttgcc tttatttctt tgatattctt gttaattttc tttattcttg attgcttcaa 61 caattctgtt tacaaaatct tcaagacgca tgggccccaa atctccgtct tttcttgatc 121 ttaccgcaac agttctgttc tccatctctt tgtcaccaat tacaagcatg taaggcactt 181 tttcaagttg cgcctccctg attttgtagc caatcttttc attcctcaaa tcagcttcca 241 ctctgacgcc tttctcttcc agcgcttttt taacttcagc aacatagtca tgctgttttt 301 caagtatggg cagtatcttt acctgcaccg gtgaaagcca tacagggaaa gctcccgcat 361 aatgctcggt caaaatggcg atgaaccttt ctatgctgcc gaacacaacc ctatgaatca 421 taacaggtct gtgcttttct ccgtcaggac ctatatacgt caagtcaaat ctctccggca 481 tctggaaatc gagctgtatt gttccgcact gccaggtacg tccaatggag tcttcaaggt 541 ggaaatctat cttaggtccg tagaatgctc cgtctccttc atttatctta taatctattc 601 ctttcttttc aagagcgttc ttcagtgcat ttgtagccct ttcccagtct tcatccgaac 661 ccatggaatt ttccggtctc gtggacagtt ccacatgata tttgaaaccg aaaactttat 721 agaagtcatc aatcagactt ataacaccaa gaatttcgct ttcaatttga tccggagtca 781 taaatatgtg ggcatcgtcc tgggtaaagc atctaaccct cattaagccg tgcaaaactc 841 cggaaagctc gtgcctgtgc accagaccaa gctccgccag cctctgaggc aaatccctgt 901 aggaatgaag ctttctcttg tataccagca tgcctccggg acagttcatc ggcttgatgg 961 caaagtcggc ctcatctatt ttcgtaaaat acatattctc cttgtaatga tcccagtgcc 1021 cggagcggtg ccacagttct tcgttcaaaa ttatcggagt ctttatttcc tgatatccgg 1081 cttttctgtg ttcttctctc caatactcct ccaaaacgtt tcttaaaacc attccctttg 1141 gcataaagaa cggaaaaccg ggaccttctt cataaatatc aaagagatcc agctcccttc 1201 caagctttct gtgatctctc ttctttgctt cctcaattct tgtaatatac gcatccaggt 1261 cactcttctt ggtaaaggaa gtaccgtaaa ttctctggag catcttattc ttttcgttgc 1321 ctctccagta tgctccggca accgacatca gcttaaaagc ctttaccttt cctgtggatt 1381 ctatgtgtgg tccggcacac aaatcaacaa aatcaccctg tttgtaaaaa gatattgttt 1441 caccttccgg caaatcccga atcaattcca ctttgtacgg ttcgtttctt tcttccataa 1501 attttatggc ttcttccctt ggaagagtaa atctttcaag cttgtagtcc tcttttatga 1561 ttttcttcat ttcctcttcg atcttttcca gatcttccac cgaaaaaggc ttttccacat 1621 caaagtcata ataaaaaccg ttctctattg caggccctat tgccagcttt gcatcgggat 1681 acagcctctt gacggcctgt gccagtatat gggatgtggt atgcctgtag gcgtctcttc 1741 cgccttcatc atcaaaagtc aacaagttaa gagtgcaatc attttcaagc gggtaactca 1801 aatcttttac ctcaccgttc acctcgcctg caagggcaac cctcgcaagc cccgcactta 1861 tactttccgc cacttctttg attgtaatcc cttcattgta ttctctaaca cttccatcct 1921 taagtgttat tttaatcata aaatacctcc tttatactaa atagaaaact ctcatccctt 1981 aaaaagcaag ggacgagagt tgtctcccgt ggttccaccc taattgttac tcattgtgac 2041 tataacgtaa tcaccgtttc aactccgagg tggtcttcga ctgagattcc ttaaaggtac 2101 tcgcagccaa tgataccttc tctcttaaag gaatgattca gtctactctt ctcttcatcg 2161 ttgacatacc atatcaattt ttaacgcact atatcaattg tcaaagatat caatttgtta 2221 aagataatta tatattttta catcttcaat gtcaactata aaaaatacat agacttttct 2281 atatatgagt ttagttccat ttttttgttt ttattcctgt agttatattc tgtaattctg 2341 ttattcactt tttaagttta cactgatttc ataaaatttc ttccaagacc agtccttgtc 2401 tttaaacatg tctacaattt tttctcgttt tcggtcgcag tttgtttgtc atttttgatt 2461 tcccggaaat aataaaacaa tccgtttcgt ggtataatgt ggattagcat taattggagg 2521 gagtatatat gcgaacaacc agagtggaaa gattcaaaaa actcagacgt aaaaaaatta 2581 aaaaatttat catatatacc ttcatcctgc caaccacttt tattctactg ggctacttgt 2641 ttacaaccat tatcattata cccataatga cggggaataa ctagaaaagc tggcatatct 2701 gccagcccat ctttttttca ttcattttca ttcataacaa tgctttcatt tctttataaa 2761 actttcattt cttttgattg gagtatccag ggcttcatgg ataaaaacct ccctgacatt 2821 gccctctatt aaaaactgaa ccttgtctat gcccggaagt tccgtaagcg aagcaacaat 2881 cgagttaatg gtcataagct cggcagtgga acctcctata tgattttcaa caaactcttt 2941 cgacaaatta accgtgcaaa ttccgttttc ggtcctgacc gacaataact ttgtgccctc 3001 gggaataaca ggatccaatc cttctgtttc gggacctttt gcaagttcct caaaaactac 3061 cttttcaatg ctgtccccag cctttacttt cactgtcctt gtctcgggag ccaccttttc 3121 tgattgaaag tcaccgaaat ataccattac agtcaatgtt tcctcttcct caggttcctc 3181 ctcggatcct ttctcagatt ctttctccaa atccggttcc tgaatttcac taccgttacc 3241 ttcatcgctt tgctgctgtt gttcattgcc ggcctgtccc gtacctgttc ctccggaaag 3301 gctgcaccct gccgcaaaca caagaatggt caaagctgca attaatgtta aaattctttt 3361 cattaactct cttatcagac tttaaaaata ctcaagtctg acaattgacc cccctttgct 3421 ttttttgttg taaagcaagc ctcataacat acgcttaaaa caattatact tcaaaattaa 3481 gctttatgta ataccatttc aaatatttcc acaaatgcca ctcagtttac cgtaataaag 3541 tccttgatat tgttgaattt actctggcct attcctgaga cattcattat gtcttctatt 3601 gatttaaatt tgccgttctg ctcgcgataa gccactattt tggccgcaat ggccggcccg 3661 attcccggga gagaatcaag ttcctccaca gttgcagtat ttatattgat ttttgaattt 3721 gcagtcttgc tgttttcact actacttgca ttttctccga ctaccgcccc gccgctgtcc 3781 tttgtaacgg ctattcctga aacaccccca ttgttggtgc tttttcccga attgcttttt 3841 gcatcatttg agcctgaact gtttttgctt gttccgccgg aaacattctt cgactgacta 3901 ttcttggttg aattgcttcc tgcagccgta cttttatttt cagtattgcc cgcagcaacc 3961 tgcatatcgc cttcttcacc aatatcctgc cctgtagtct cacttttgga cattaccctt 4021 atcataacat tctcccggag ctcataagcc aaatttatat tctcaatatc cgcatcctct 4081 gtgggacctc cggcaagttc aatggcatct tgtattatct gacctttttt cagtgtaacc 4141 acaccgggtt tgttaacctc accgacaaca tacaccttta tttcatctgc agcttcttct 4201 ttctcctgaa ccaatttttc cgttgtcttt tcctcaccgt tttccgcttc cacggtatat 4261 tgaccggctt tcgccttgct tataattata tcctcaccgt catttgcaag aagaaatccc 4321 gtaaccgaag tagttacaat caatcccaat atcatgagcc caactattcc ttttttcata 4381 cttacttcct gattaaaaaa atccctcagc aaaaatatcc cccctcaaaa caaattcaat 4441 tacaaattct tagacagcga cttccgattc caagctacat acaatgtcgt aatatgtaaa 4501 aaatttatta aactgtttat atattataat aattgttgtg cataaaaatg taaatactca 4561 ttcctttatt tacctgcaga ttttttcaca tatctctatt tttttcaaca tttttttgtt 4621 atactttaaa taatgttggt ttcttatttt tcactgataa taaaaacatc atgattgact 4681 ggaggaaata atgaaaaggc tattgttact tttaatcatg acaatcattc tgttttcaaa 4741 tattgtgact ttaaaagcac aaccattgga tattaatgca caagcataca ttttgataga 4801 ttccaaaact ggtcaggttc ttgctgaaca caatccggat cttagaactt atcctgccag 4861 caccactaaa ataatgacag caatactggc actcgaactt ggagatctca atcaaataat 4921 gactgtcagc cagtctgcca tagatgacat aggtcctggc ggcatgcata tcggtttgct 4981 gccgggcgaa caactggagc tcagatactt actggatgct ctcctggtga gatcagccaa 5041 tgagactgct tatgttattg ccgaaaacct ctgctcctcc cgcgaggaat tttacagact 5101 tatgaacgaa aaggcaaggg agcttggggc taccaataca aattttgtaa atccctgcgg 5161 tattgacaat ggagaaaagg gaaaaaatca tcttaccacg gcaagagatc tcgccaaaat 5221 agcgcagtat gcaatgacga taccggaatt tagggaaatc gttcaaaaaa ctattatcaa 5281 aatacctcct acaaacaagc atgctgaaga ggttattgtc ggtactacca ataaattgct 5341 gctctacagc aactcaaaat acaaatcgga acactataca aaaataaccg gtataaaaac 5401 gggttatacc gacagggccc ttaacaactt ggtttcttcc gccgtcaacg atgaaggaac 5461 ggaattgatt gctgtggttc tcggcgttga gaattatgac atggtgttcg aatattccaa 5521 aatgctgttg gaatacggtt tcaaaaacta ctccgttcag cctgttattg caccgaactc 5581 gtatataacc tctgtacccg ttttaaaagc agcgggaaat cacaacttgg atattctggc 5641 atcgccggag ggactcaaat gcctgctgcc caacaattca actaaaaatg attatgaaat 5701 tgaacaacat attttagaaa acatagaagc tccggtaaaa aaaggggatg ttctcggata 5761 catcgaggtt aaaaaagacg gtgtcaccat cggaaaaata gatgcagtcg cttcaaggga 5821 tgttgaaaaa cttgagccgc cggttgaacc tcaaaacata attattaaaa cagcaaacga 5881 tccgattttg aaaaaagtta caacaggagc attgatcttc ctgttaatgt tccttatgtt 5941 aagatttact ttgcgcagaa tttcacgaag ccttcattca aaaagataaa aacaaaaaga 6001 taaagaattt catccacaaa taatataatt ataatataaa ctataatcca aactataata 6061 taaactattt atttgaacta tttatttaaa ctgtttgttt tttaaactgt ttttatggat 6121 taacataact ttttgcaatt tgctttgtaa aatatcgtta caaagcttct gttttaatgt 6181 tataatttat atgttaaatt tgaaggaacc atttatttgt tcctttattt gcctaaagga 6241 gtgagtggta cattatgaaa acttcaccgg ttttcgaagt aagaacgatt aaaaacttaa 6301 gagacatgat tgagcaaagc agcaaactgt ttgccaacaa agatgctttt cgcgtgaaaa 6361 caaaagataa ttcatataga ggaattactt tcgccgaatt caagaatgat attgatgctt 6421 tcggaacagc cctgcttgat ttgttgggaa cagaaaaagg atttgtcgct gttataggtg 6481 aaaacaggta tgaatggtgt gttacctatc ttgcaactat aaacggcgtc ggagtagtta 6541 taccactgga caaagaacta ccccttcccg aactggaaaa cttgttaaaa cagtccaatg 6601 ccaatgccat tgtctactcg ggaaaatttc atgatgcaat taaagaaatg tcttcccgtt 6661 taagcaatat caaatatttc attaatatga acaccaatga gcatgaggat gataaatttt 6721 tatccttttg ggttctcctt gaaaaaggaa aaaaactttt ggaatcagga aaaaaggact 6781 atcttaatgc tcccatagat gaaaacgcaa tgagtgcaat gatttttact tcgggtacaa 6841 cgggccaggc taaagccgtt atgttgtccc acaaaaatat ttgctcaaat atgatggccg 6901 tttcagcttc tgtttatatg gacagcacag attccgtgct ttcaatcctt cccttgcacc 6961 atacctatga atgcaccgca ggtttcctca ctatgatata taacggtgca acaataactt 7021 tcaatgaggg actaaaatac atcggcaaaa atctcaaaga ggcacaaccg acaatcctta 7081 ttctcgtacc tcttattctg gaaagcatgt acaataaaat atgggaacag gcttcaaaag 7141 acaaaagcct taaatttaag ctgaaagccg gactttttat tagtaatttg ctatataagg 7201 tttttaaaat tgacatacga agaaagttgt ttaaatccgt aattgacaat gttggcggta 7261 aattaaggct ggtcatttca ggtgctgcgg cccttgaccc tgaagtggca aaaggatttg 7321 aggccatggg tataaaagtc cttcagggat atggtcttac cgaagcttct ccaatagttg 7381 cagtgaatcg cgacaagtcg tacagacacg attcagtagg acttcctctt cccgggcttg 7441 acgtcgaaat catcaacccc gacaaagagg gatttggaga aataatagtc aaaggtgata 7501 gtgtaatgct tggctattac aataatgatg acgccaccaa agcagttctt aaagacggat 7561 ggctctatac cggagacctt ggccgcatgg atgaaaaggg ctttatatac attaccggac 7621 gcaagaaaaa cattatagta accaaaacag gaaagaatat tttccctgaa gaagttgaag 7681 cctatcttaa caaaagccca tatattaaag aatctctggt ttcgggaaga gaaaacgata 7741 aaaacgatga aacaatagta gtagctcaaa ttgtacccga tatggatgca atcaaagcca 7801 agcttaaaac ggacacagat ccgtcacccg aagaggttta caaattgatt aaggcagaaa 7861 ttagggctat aaacaaaaac atgccggtct ataaaagagt tgttgatata accattcgtg 7921 aaaacgaatt tgccaaaaca tcttccaaga agattaaacg atatcttgag aaaactaatg 7981 tataagaaag atgtaataag taaaagatca aaagcctcag ctttataata ctattccggc 8041 tgaggctttt atttatgctc ttttaatatg ttcttttaac gcgcttttaa cgcgcacagt 8101 gtaaaacttc aaatctatac tcctgccaaa ttgctgccta ttaattccat ccgacttttt 8161 taatttatat gccggatata gaatataaat taatttttat cgaattgttc cgataattaa 8221 taaagaggta atgcacgtct accacttctt ataagtagca ggtaataaat agaagtaccg 8281 gtttgctttt aatgagggga accatcttgt gcctcgttga aacatcactg agttgcctat 8341 ttttaattgt gtttaattgc caatttattt aaactgattt aataattgga gaccgttata 8401 tgaattcgaa agatattatt gccaaaagcc gtacggaatc agatattttc gcattaaaat 8461 gtatgaagtt ctgctttatt tttgcgataa ttgatttttt cattgttgaa ttaaacaaac 8521 aatggaaagc cgatgccgga gattggttga ttgctgtatc cgggatagca gcactaatcc 8581 caatttttta ctataaattt tcaaaagaaa agcaaaattt tgttgctgtt ttgctgattt 8641 cagcagaact tatttccatt ggattatata taagctcatg ggtttatgcc gcacccgcgc 8701 ttatatttcc ttttgttatc ggagcattgc attacgactc aaaaattttt aaaaaattaa 8761 tgcttatcaa aattcccgct ttaatagtca tgtcgctttt ttgtacttct tgtacaacgg 8821 aacatttatg ctggatgacg taatatttac aaaaaagctg gccatcggct cagcagaata 8881 ttatttgata cagctattgc aaagtcggca tcttccattt catccaaatc agaagtaatg 8941 gcaggcaaag ctgagggaag ccaggattat atacgtgaga ttgaaactca cattgataaa 9001 actcttgaac attctgatat aattacaaaa ctgacagaat ctatgagtga aatcaccgaa 9061 aaaaatcaaa acaatattga atgtattgtt gaaaacgtaa ataaaatcaa tacttccaat 9121 caacaaacca ttgaggaatt tgagtatatc aggcaaaata atgaattaat aaacgaagca 9181 ttacaagtca ttaacagtgt atctgagcaa accaatctgt tggctctaaa cgcttctatc 9241 gaagccgcca gagcgggaga agcaggaaaa agatttccgg ttgtagccat ggaaatcagg 9301 aaacttgcag atcaatccaa cgcatctgct caaaatatta ctgacatcct gaataaaatg 9361 ggtgaaggaa ccaatcaatc cttaaaagca attaatctga cacagacaaa tatatttgat 9421 actctcgaac ttttggaaaa cactgaaaag gatttttcac aaatgtacaa ctgccaaaat 9481 tctgttataa atgaaataat tcaatctgaa aaacttatca aaaaattgga agacgatatc 9541 caagccatta aatctgttat gggacaaacc ctttccgaat tcgaagcaac ttcatcggaa 9601 atatcagata tttccaatgt tttagaagaa ctcaacaaat ctttccaagc catttctgat 9661 tttgcagaag atgttcagac aagttcaaac agattgatag aaaaatagaa caaaattgcc 9721 actccaggca gaaaatattg caacacgttt tctgtctgga atggcaactc ctaaccgaca 9781 actcatagtt tactgaagca attctgtcat tttctcaaac aacttataaa taattacggc 9841 cgtctccgct cttgttatat ttcttaaagg agcaataagc ttgttatcat cccctttaat 9901 tattcccgcc ttcaccaaag cagcaacgct ttccacagcg taaggcgata tctcggagaa 9961 atctttaaat gcttcaagtt ctgaaacatc tcctgtatca aggtttatac cgactacttt 10021 aagtgccctg tttacaataa ccatcaattc ctgtcttgtt atcggagttt cagggttaaa 10081 tttattgttt ccgactccgg ttacaattcc aaagcttctt gctattccta cagcttcgta 10141 atagtattta tctgcagata catcatcaaa gttctctgta aactctgcct caagacccaa 10201 ggctttcaca atcagtataa ctgcatcagc ccttgttata tttaatcccg gactgtattt 10261 tgtacttgaa gttccgttta ttatgccttt tgaagcaagt atttctatct gttcttttgc 10321 ccagtcatat ccttttaaat catcaaagga cttgtatcta taggctactg catattttcc 10381 ggactgctgc acgctaaata tgactttccc ggcatcctcc ttgtatacag ccattggaat 10441 tgcggacaac ttaccgctgt ctccaacgta ccatacaaag attctatcgg ttttcttaag 10501 ttcatctccc ttcggagtat aatccacaga tattttaatc gatgtcttat tgctcctcca 10561 atttatcagt ctaccgtcaa ccaaaacttc cagttgtatc accggcctgt cgcctatttg 10621 agctttttgc tccatgctca aatctgatgc ttcaactttt gacactctta ccgatatact 10681 ttccgctttt tctatgtctt tctcttcaaa catgtcaagc ggtatttcca cggttgcaac 10741 cggtgtctta atctctatct tcctgccact ctccgtatcg gtaaatatac ttgaaggaag 10801 cttctgttcg tatacttcca caccgtctgc cttcttaatt tcaatactta ctttttttct 10861 tcccgccgga tcgcttccaa atttctcgaa ggcattttcc aaatccctgg ctgctacagt 10921 tgaaattgcc gcgtttcctt ctgtttgcgg taccacagtt atgttgcctt ccttatccat 10981 ctgaaccttt tcttcatcat ccgattcctt gtctccaccc ggccccggaa tcacttccac 11041 cggttcagat ataaccggac ctgcagatgg attgtcggcc ggtggattaa ccggtggatt 11101 aaccggtggt tcaatcggtg gattaaccgg tggttcaacc ggaggctcgg ttggcttctc 11161 cacctttatc actgtaactt ttacagtttt tgatacttta tttccctggc tgtcaacagc 11221 agtaaacgta acaattgttg tgccgacagg gtataaatca ggagcatcgt ttgtcacatc 11281 aacaactccg tcgaccaagt cataagctga tgcctcacca agtaccacag aaactttttc 11341 ttccgttgtt tcaacagtcg tatccatagg taccataagt tcaggaggtg tagtatcaac 11401 aaccgttact ttttgttctc cagaaacaat aacattgcct tctttgtctt ttactgtcca 11461 aacaaccgtc gtaacaccca aaggatagtc ttcgggagca ttgttgctta catcagcatc 11521 cggcatattt tctacatatg cagtacctat gtctactttt gtgcgctgtc cggttgcttc 11581 cgctactata tccgtaggca ctatcaacac aggtttctct ttcttctcca cagttacagt 11641 cactaaattg ctttgtccgg actcttctcc aaaaatatct actgccgtta ctgcatatat 11701 ataaatttct ccctctgtaa tgtcggtatc gataaacgcc ggagttgtaa cttctccaat 11761 ctgctttccg tcacgatata ctttatagcc tctcaggctg cctgtggacg gtgtccattt 11821 aagttcaatc ctttctttgc ccacatatac agcctcaagg tctgtcggcg ccgtcggagt 11881 ctgcgtgtat ctgcctttaa ttttcacagt atactcctca gacggttcac tttgcgtacc 11941 gtacttgttg aatgcagtca cataaatctc gtggcttccg gcatttaacc ccagtgaagt 12001 actgaacaat ccttcgctgt tcgctttaag cataccctgt aacgttccat ccacccatat 12061 cattattcct gattcagatt ccgcttcacc ttctatctta actgtataag gagcttcctc 12121 tgtcggctca cttaccgggt aaagcacagg cgtttgaggt atggaggtat tcagcactat 12181 tattatcgga acattgtacg tataaccttc cagcccttca atatctgata caaagccttc 12241 actccaacca tataccgagt ctgatacaga cattgtgcct gtttgcctta ccaaagccgg 12301 atttaaattc ctgccttcca cagtcaccgt aaacagtccg acatatgttc cgtccggagt 12361 atcttccggt aattctgccg tcgcaattgc agttacgccc attcccgctt ccactgtttc 12421 cacaagtgtc tttccgtcat aacctgtaaa cttgaagatt cctgacggta ctacataccc 12481 gtcttcattt cgaagctctc cgacactaaa gcttacttta tcaatatcat atctcataga 12541 agactcaaaa acatcaaact caaatcctac ttcttttgta gtacttacaa caacataagg 12601 ataacttaca tccggcacag ctcccaaatc cggcagttcc aacatattca gcgaataact 12661 ttcgctttcc tcaccgtcag gagcttttac cactacacgg tatttgcctt ttacagggtt 12721 tacaattctt atataatcca cactatttat taatccattt atttccgcac cctgtatttc 12781 gtttctgaca actccttcaa catttccggc aacgtttcct tccggatcat aaacggcaaa 12841 ttcaagtgtc gttccccatt ttgcagccat aaacaatctt atctcaccta aattgccgtc 12901 cgactctata aacatctcat cctgttctcc gggctcaata tctcttccaa gcggctgact 12961 aggcttataa tatgcacgtc ttgcttcaat ctgctcctga gttcctacaa agaagtatga 13021 tgtgtacggt ccttttacat cacctattga catcgtgccg ggctctgcga caccaaagaa 13081 agcaacggct acatatccac cggcatccat catcgtggac cttggtatac tgaaaggtat 13141 ttccacagtc acagtttcgc ccggtgcaac agttacagaa ttcgtatcgg gtacagccac 13201 aagaccggca ctgctgtata cctccagaga tggagatatt gtcaaagctc cggtataaag 13261 attcttgatt ttaagtacag ctttaccaac tcctacttca tttgcaggtc caacggcaat 13321 atccggcaca accatgctca ttacttccac aggaagtggc gggtcaattt tcctccactc 13381 atcaatcgct acaaacattc cgttaacaga atttgcaacc gacagttccc tggaaagtgt 13441 tgtacctgcc attgctgtag tgctgatggt attgcttatc atgtcttcaa atatctttcg 13501 ctgttcatac cttaagtcta tctctctcaa acttatctga gatttcaagc ttgccatcag 13561 catagaatca ataaacaagg aactcatcaa tccgaagtaa ggactaagag gcaaaaatcc 13621 aataacaagg ttaaagtaat cataggcagg cagcattgct tttattccat tgacttccca 13681 tcttgccgcc agatttgaat aacctctgct ctgtatcttt aaggattcaa ccaatggttc 13741 tttgtattct ccgattttca cttgatatgg aatcagatcc ccgtaatatg gatgatatac 13801 ccaaacattt ttgtacatgc ctacaccttg agccatttct ccatcgccta tgctccacat 13861 gccttccagt tccttgttta accccttcaa atattcaaga agaggatcca aaggatagta 13921 agatggtacg tttgtccgtc catagctgta ggaatcaagc agttgcttgg cttccatcaa 13981 ctcaagggct accctggact tcaattcctt aatggttaac tgttcggctt tatcaattaa 14041 ttcctgaatc atagcatcca tctgaccgtc atccaattca ggcgaattca cataaaagtc 14101 ctctaccttc tttctatcca caagtctaaa tgctttagca ttaatcctct caataacttt 14161 atcaattgct tcttctcgag aaatcccttc cgcaagaagg tcataagcaa atcttacgag 14221 ctcgcccatc attttacggg tttcctcttg gtttacttta tactgcatta aatcatccgt 14281 ccagcttata agttctacaa ctccattcaa tccaaatcgc tcaagaatta tttcaccggc 14341 actggtaggc catccaatta ttgcttgcat tctttcaaca ttgtactcat actcagcctc 14401 aaggtcctta atcttctcct ccaatgccaa tttttcttcc tcagtcatat ctccagcttc 14461 aagtttccgt tttgcttctt caatctcctt ctttatttcc ctaagttgtg caccaatctg 14521 ttgcagtaat ttttgctcct caggtgtata gtacagtttc gatggaaatg gattcagcgg 14581 aatttcgtta tccaatccaa atgcaacttt aaatatgtca aataaattca ccataaaatc 14641 aacgtaagat attacagcag acataccatc gattgccctt gagaatcttt cagcctcatc 14701 agcctcaccg acatattctg caacatcaac tacaaccgtt gcaaggtcat gtactgtttt 14761 gttcatgagg ttctggagat tgtattcaag tctctcaacc tcctggataa gcagttcaaa 14821 atcacctcgc catactttct gaatagccat tggcgaaact acaatgttat catttacctg 14881 tgtactatgt acagcaagac tcggaagatt catccaatcc tcaagcccgt tcgctacaat 14941 ttcaaacgtt cctgacttcg tttctcccgc ataaacgttt ccaatattaa gaacacttaa 15001 atccctttgg aagaatccat cacctgatac tattctgata acctcgattt ttcccgcacc 15061 gggtatgaca ggcagcccaa cggtaacatt acgggctgta ccgtcaccgg tattcgttac 15121 aatggcttcg atttcataat gactttctcc tattttgtta agcttatagc tgatatacaa 15181 ttttggaggc ggttcaattg taaacttttt cggtcctata tatccctgat acactttgcc 15241 gtcaagtaca tagtaataca caacataagc ataataatct ccgcttatat ctccaaggcc 15301 tgcccggctt ttgatattgt acctgaatga gtaattactg tcaggtccaa ttttatctac 15361 tatcatccat tcgccattgg acatagcatt accaatatca tccgcctcta ttatgaatct 15421 ttctgtaacc gatcttcctc catcagcaat gttgcccatt gtatccaagg gtttgtctgt 15481 aattataatc ttaaatctga cgtcatcaat ttttttgtcc tcgtaaggat tgtagaagac 15541 aaactccgca ttaaacgcct catccaccat tgcaacatcc tgtgaaaaac cgaaggatgc 15601 agctgcattt ccggcaggtt cgggaagatc actgacatcc atattgcatc tttctttcag 15661 gaagtttctg ctgtactttc ttacttctcc atcctcatcg ttcccgctta cttcttttac 15721 tccaaacttt ttaaggtcat tttcaggtat aggattggca ataatgtccg acggatagta 15781 tgttattcta acaggcaaat tcagcgaaac ctcaatttcc tcaccattta agcctaatcc 15841 tgtaccgctt atggatattg tcaaatctaa ggcataactc ttgccaaaca atctctggat 15901 atagcctttt ggcatcgtat agcttccgtc ttcattctgc ggaacaccga taatataagt 15961 atttgtctcc tcatcccatg atattttttt gacaaccctg tttccgtaat acagccacga 16021 caatcctttc aaccaggcat caaaattctc aggtgtcact tcttttggtg caatcacctt 16081 gtactggtcc ggagtgtccg taggtataac atccgcttcg taatacaagc aagataagtc 16141 aaagctccat cttatgttct ttgattctcc cggaccaaaa tcccctaatg caacagaatt 16201 gttcgttatc tttccatagc tgagattgac cgaatatgcc ggaaggtcaa gattatcata 16261 attaatttca gcttctaccc aataaatctc tctttcgctt gaataattct taattctaaa 16321 ctctcctcca acacttccgt taatcaagtc agtatctctg accgtaacct catctcctgg 16381 gaagtttgcc accagctgag gctttccggg aactgtattt atctgctgct caagaactat 16441 ttcttcagta ctccgcaatc cttttcttat ggaattcatt atactgctgg aactccagcc 16501 aagatttatt tttttctttt ctataactac tttctgtgga atttcattta taaccgcagg 16561 tacaattatg ctctcttcaa cactctcata cccggaagca cttactttca gggtgtatat 16621 acccgcaggg atattttcaa atctgaatac tcctttgcct gtaaccactc cctgatacac 16681 tttttcatcc atcggctgct cccaatcaga tgtgtgaggc ccgataagag taatttttgc 16741 atcttccaca ggagcataat tgctgtctac ggcttcaaga gttattgtac ctacatgcgc 16801 tgctccaacg tttatcttta caggaatggt ttttgtaccg gcattggacg tcaaagttat 16861 aacatcctca tatatgcccg gtcttacata ttcattaggt aaaatgttta ctgcaataat 16921 cgcacgagcg ttttcgtctc ttatggacaa tcctttaccc atcggcagaa tcaaatccgt 16981 tcctgaggta gtcagggtta tccacgggag tttttccggt ggcgttacat gaaggtcttt 17041 aatggaaccg gtacccacat tgtatacaga aataatttga gttatcattt ctccaggtct 17101 cactgcgcct tcaattgccc cggaactaac attacttttt gtcacagaag gtttcaatcc 17161 tgttatttct atataatact ccggttttgc ttcaacaacc cgtacctcaa tgccggaagt 17221 atatgtatat ccttcattgc agccaacaac aagtttcaat gtataaatac ccgttaccgc 17281 ttcttcgccg gcctttacaa ccatgttcaa atcaacggat tctcccggtt cgacagtctc 17341 aggcaagtgg ccttcaaatt ctgcaataac gtaatctgac gattcctccc aaattttatc 17401 gatattgatt gcagtaagag gtattgttcc cacgtttacc aaagtaatct ttgcactttg 17461 ctcatatcct gccgtaatct ccaatttctg cggtaaggaa acgtaaagtc cttcaacata 17521 gaacactttg gtactgctgg atttcaccgc tccgtttact tttgcctcgg ctcttaacga 17581 ataagaacct ccaaatcctt ccggtaaatc aaactctccg gtataacaac cgtttttatc 17641 tgttttagtg tctgtgcgcc actcttcttc accaactatt attatggtta cttcggcatt 17701 ttctattgga gtaacgccat cgcccatggt gactttaccg ttaatcctta ttgcttcgtt 17761 taccgaataa gtctgctttt cagattccac cgttactgta tagtcaggta ctaatttaaa 17821 tgcactgtaa acggtatttc gccgttcaac accgtcatta actataatct gcacaatgta 17881 gtctccagcc tcaagtcctc tgtcaattct tgttttgaac agacctttta ccttgtcata 17941 ttccattaaa cttgcaaata ccggacttcc tgccggatta tcattctcag cagactgtcc 18001 tttaaataat ttcaactctg cagaaattcc gtcctccgtt cctaaaggcc gccacaattc 18061 gtccgttgac gttactttca ggaagtattc aatatcttcc ttcaccgtgt acacttctct 18121 tgtttcctca agttccaacc taagctcatc gtttaccttg taataagccg tctttatggc 18181 cgcttccctg tcagccatag gtatatcact gtaagcatca gcaaacacca caagctcata 18241 ataaggagca gtaggtagat agtccgccgt ccattcaatt tcaccggtaa caacagctcc 18301 cggctccaat actgtagatg tgctgaagct tcctgccaaa acattattta cgtacaatga 18361 agtggtaaaa ggcttgttaa ttgccgcatc gccaatattc ttcaatctta cctgggtaac 18421 cacagtgtct ccgaactttg aagtaccgtc atccggaatt gtttttattt cctcaaccga 18481 caacttcgga agtttcacat taagcggtat attcaagtca tatacaaacc gattattgcc 18541 ttcattatac tcccgtatac tgttattctc atctacataa acttttattg atttagttcc 18601 tcctacaggt ctgttccata caaatattgc ggaactggtg gtgcccttca gtatttcatt 18661 aatctccttt gtacctatat atacgtcatc agcaaataca gaaacattga aaggtttatt 18721 agcatcagca taaccgacat tggcaaccga tacatctatt accaaaggct gtcccggctg 18781 tataaccata tcagcaggtt caattgaaac attttgaact gtcaagtccg gatatctaag 18841 tcttatgttg ggtgactgca ttactgcctc attatcccca cgttctattt ctacaatatg 18901 aggaatcggt ccgtccgcaa caactttaaa ggtttgcacc ccttcagtat ttactttcca 18961 aactgccgaa accttgaccg tgtttcgtcc ttttgaatag ggtaaaccat ctattacttt 19021 tgcttctatc agcttatcat ttaccataaa cgatacgtta aacttttccg catttgccat 19081 tccatcgttc tcgataacgg cagacagtgt tatttcctga ttccagtcaa gtattccgtc 19141 ttccggtccg ttccatgtaa attctgtgac cttcagattc gggaaaaatg cattttccgt 19201 attgacggca cggctcaact gattattgtc aaaatcagct tcgtcaacga gtcttcccat 19261 atcgtttgca acaactgtta tcatatgatt tcctgcaata ttcagccatt cgaaggttac 19321 atcctttgac tcgcccggat ttatgctttc cgttactctt acatagtctt taaacatgtt 19381 attgacatag aatcccacaa ggaaagaatt atcagtcgca gcataacctc cgttaaagat 19441 cgttgccgtg actttaactc tttccccttc ttttggatta tcgttgctca aacttatatc 19501 agtaactctt aaatccgctc tcgtctcatt aaccgtaact tgcatttcgg ttgtcgcttc 19561 aacataattg tcatcaataa cagtaagttt taccttataa gtacctgaat taagataagt 19621 atgtaccgga gccacaccaa aagctgactc accgtctccg aaatcccata taaagctttg 19681 gatgtagcca tctttgtcaa atgagcgcga agcgtcaaac tttgtgggtt tcaacacatc 19741 aaccgagaag tccgcacccg cgtctgcaaa aggtttaaag ttcactcggg cttttgcctc 19801 agaaactgcc tgtggagagc catttccggc aattttagct ttaagtacgt attctcctcc 19861 cttctccgga agccaattaa catacacata ggttgaattc atcggttcaa ggttattaaa 19921 tcgtccttca cctattttta tttcctcttc cacttcacct ttaaaatcaa gtttcgttgc 19981 aaaaaattcc acaatgccac cttcaacact acggccctca ttataaacag cagctcttac 20041 tctggtcatt tgaccctcgt ttgggtacac tccgatatca taataagcat atttttcttc 20101 aacttctaaa gttttaggat ttacatcata gtatattctt gcatattcaa ctgcacttat 20161 tacagcacct gaagtgaaat ctatcgtata agttgaagga tgataatatc tactttgctc 20221 attattgtaa tctctaggtt ttatacttaa tacaggaatc tcatccacta tatatatgtt 20281 tccgttgttt ttccaaacat tgttttttcc aagtgctacc ggttccgtac cctctgcatc 20341 catttctctt gtcacactgc ttatcggagt gtcaggcatt ggatccttca gcataagtac 20401 ttgatatttc ggcatttcag gagcatcagg attctcttct attgctggca ccgtaaattt 20461 aagaatcttg ttttcatcat ccggctgtct ctcaacattt aaagtctccg gaacatatat 20521 tgggaacttc attcctgtgt caagatttat taaataattg gggaatcctg tgttgccaac 20581 atcaataagg ctcagtacac catctgtacc gcttttatct ccgtaaatgt tgtcttttcc 20641 tattatttcc gtatcaacac ttactattaa cgggttcagc tgcacaccat tgtaatctcg 20701 atgagttagt gtcgctttaa agtcacggaa ttcaccctca aaaggttttg ctctttcctc 20761 ttcctcatac ataatccatc ttaccagcca gtagccgcta actcttccct gaggttctat 20821 atctcctaaa ttcaacctga aactgttgcc tgtcttactt ccaaaagatg tatccactat 20881 ttcaaactga gtcaacaaac cggattggtt ggtttttatt tcaagttgtc cggattctat 20941 caccaaattc ttagccgttc cataacctac attttctgca actaccccga gtctgaaagg 21001 ctgtcctgaa agtatcttgc ccggtacata ataagttagc ttaatcttcg gctgtggctt 21061 tattgttatt tcctgaggtt ctgtctcggt ctcaacataa cgtccattta cgtaatacga 21121 gactatcgcc cgtgcaagat atgtttggcc ttccgggtcc tctcctccca atccgtcacc 21181 agggataagc tgccatgtag cagttacttg ttctcccgca gacaaagaag cagaaccgtc 21241 aagagcggaa attccattca gacttgtcag tattataaag ttttgcccag taatattatt 21301 accttcagtg tctgttatca aaatccttac ttccaagttt tgcaaagcat ctttaatata 21361 tccgttttct atcttcaggg ttgcatcaaa agcttgtctc tccaaggtgg ccgtttggct 21421 aagtttaaaa cttgctattt gagtgtttcc tgctgcacca tcaccgtaat caatattatc 21481 atcttctatc ggaacaaaat aatcgaattc caccaattgt tcattggcaa gattaacttc 21541 catcttttct tcgccttcgc cggttttgac ttttaataca gcattcttgt ctcccggatt 21601 ttgtaaaggc agcattcctg tcacttgatt tgcatggaat acaggtaatc ctgtatcact 21661 gtcaaagctt acatatttgc cccggagtac aattgcatta tatggtaaac cggttttatc 21721 gttaatgccg tatttcaggt tataataacc cggcttaacc ataatgctta cacgtacact 21781 tccatgggca ggaatttcac caatataacc tcctccaaca atgcttattc cagtatcttc 21841 attattttcg cgaagcactg aagcagtaac gtcagtaacc gcgacaagtc cggtatttat 21901 tactgtagct tcaataatta ttggttcggt cacttgcttt ggtaccgtaa gccacggcgg 21961 aacaaatcca aatttcgggc ttggtatatt tgtttcaaaa gttaaatcaa gctgtatgtc 22021 atatttgtct tcaattgtag taggtactac actccactct atctgcaccg gctcagtttc 22081 catggttact tccaccatgg ccgattcatg catgggcatt acattggccg tgcccgtcac 22141 atgcttttta gccttagctc ttatcgtata agtgtactca cctatcggaa catcttcaaa 22201 ggtcacaatt ccattgctgt ccgttcttcc gtaaaagttt tgataatatg ttgttttctg 22261 cccttttata atctgaacat acggctcttt cccaactata gttacttcag cattttcaac 22321 ccgctggccc atgtcatcct ttacaaggaa cgtaagtgaa cctatgttgg cacttgatat 22381 ttccactccg acagtaacca aagctttata cttaccgtca gtaaccgtaa tgctgtcctg 22441 atactgtccc aaaggagtac cttcaggcgg attaacaaca atatcaaagc ttgttgattc 22501 tcccggagcc aggaaagtct tttccagatt aattgctttc acccatggca gatttgcagg 22561 tggcaacagt tttatattct ccatttcacc aagacccttg ttggtaacag tcactcgttt 22621 ggtaacaatt ttcccaggat tcacaccgac ttttacacct tttgggtctg ttacaggatt 22681 gggtattgcc ggtctcagat acacttttac atttgctgtg gcaaccgctc cttcagaact 22741 gctgaatatt acctggtatt ccgctgtatc tgcagcattc aacggagcat tgaaatttag 22801 cataacaccg cttttgccgt taggtccaat tacagatgaa agggtggaag tatccattac 22861 cgctctgacc ccactgtcgg gtgtgagatc tacaagcacc gcacttaccc cggtaagact 22921 ctgttcagct ttcgccatat tattcactga tacaaaagct gaaaagcttg agtttttcga 22981 agataccacc gaaagggttg acggtgatgc tgtcattccc catacggtaa attctgaaac 23041 cgcagcactt ccaacgccct tttcataagc aaaagcattt actctccatt taccggcccc 23101 aagagtagta ggcaagaaat catattcaaa atatccattt tcatcggtat ttacaaaacg 23161 taacgtttct gcatgccatg cttttattat catttttccg ttgatataac ttattatagg 23221 gtcgggaagc cttggctcaa gacataaatc caacacgatc ctttgatttg ccaaaggagt 23281 tccgtctctg tatctgaagt agccggatat atgaaccgtc tccccgtgct ggtattcttt 23341 tttgtccgtt tcaactgtgg caacggtctc ttcaacaatc ataatattac ttgttgaagt 23401 tatgctttca attccgtccc ccacctcaat tgtcagtata taattgcccg aagcaagtct 23461 cataagaggt atttgaccct tgaatacaga tgaagcataa tcaaatccta tctctccgtt 23521 caacaaagtg gtatcgtctt ttctcaggat atagtacgcc cttatacctt cattaggtcc 23581 tatcagcttt gaaagatcgc tggctctttt tgccttaact tcaaggggta taaagttgtc 23641 tgtagtgcag taaatatgcg ccatgaactc gtcattctgt tcctgcgggc tcggtctgat 23701 ttcagcaacc agcgcatcag ctatattaag atttccttcc caaatacgta ttaccttgtc 23761 acttgcaggc tcctgtttta tctggttgta tggatcaact acaattttta catccgcatt 23821 tcccaagact tcaggagtgc atgtcaaatc aacaacagcc gtactatgac ctctcaagcc 23881 ttttattttc ttctcatctg acagctttcc attaatatac aatcctacac tgaattcttt 23941 aaatatcgac gtaacacttt ggttgcttac ccttgcaata aaggttaccg gctggccata 24001 ctttacggat aacggtgacc actgaacatc cgaaatattc aaatccggat acagaatttt 24061 tatataaggt acaacagcac tcacctggac tccgtaaaca ctgtcagtaa cggttcctga 24121 agcgtccgca accacactca cattatgagt tcccggttgc gccatccagc gtgcccatac 24181 cgtcttttcc tcgccggcgt taagtccttc cactgttaca gtcttgattt ttacattatc 24241 caccacaaaa tctatatcaa atttatttct gatatccacc gttccggtat ttttaacctt 24301 ggtttcaaat gtaagagatg ttccttctgt aaggattgat tcttccggaa gccatgttac 24361 aggtgagagc tcaattttcg ggtacgttac gttaaactcc ggcgtagtta cacttattac 24421 gttattgtca ttattcaatt ccacaagtac gggtacgggg tcatcaacct ttaccgttac 24481 ctcatgcttt ccggatttgg gttttacgat aaaagtaagc tcgcgagttt cccctgcttc 24541 aagaacattt atatgctgtt ttgctgtcca ctctccgtca acataaaggg atacaaagaa 24601 tttctccgct tttttcgtac caatattgga tatcttaacc ttatatccaa acggactttc 24661 gctgtctatt tttacattgt ctccacaagt ccatgtaatt tcatctgcca cgacatcagg 24721 gaaattcacc tgctgagttg tcaaggcaac agtctttgta ttattttcaa cacttatctc 24781 cttaagattg tccaatatat cattggctgc aaccttaagt acatgaacac ccggttccgc 24841 tttccatgta aaaggcacat caatactctc accgggattg atactttcat ccacccttac 24901 ataacccatg tatttgttat ctatataaaa tcctgttaaa aatccttgcc tgttcggacc 24961 tttacctaca tttgcaattt tggcgacaat gtttacaata tctccttcct gtggctcttc 25021 aggatcccat tgaatatctg aaacaatcaa atcaggacga ttgtcgtaaa catgtattga 25081 aaccgttgct gtagaatttg ctccgttgtt gtccgtcaca gtaagagtta tgttatagat 25141 tcccggaatc tgatatgtat gggtaatgtg agcccccttc ttttccactc cattttccag 25201 atcccatttg tatgacacaa ttcttccgtc gctgtctttt gaaagacttc catccagagt 25261 aaagacatcg ccagaataaa tccattcttt agtctggata tgagcttccg gaggtatatt 25321 aagccttaat tcagcagtca aagaattatt gtcttcgtta atatcctcac ttccgtccat 25381 agtatttact acagccataa cagtcacaat attatccaaa tgtgaatcag gaatccatgt 25441 aatggaagcc ttcgaattat ccatgctctt tacttcaata gtagagcttc caattttact 25501 ccattctccc tgattttcaa tatagaaatc aactcttccc tctgcttttg cataacccaa 25561 gtttttaact gtgcatatta tttcagcctg tctgtcatat gcgggcactt gcgggtttgc 25621 ctccacactt acgatggtaa ggtcacttaa tgctgaagga acagaggaaa cctggttgga 25681 ttttccactc tcattacccg cgctatccac cgcagtgact acataatagt atattttgcc 25741 atcttcaagt cctttatccg tatacacaag ggactttgtt ctggtcactg ctttaaagtt 25801 ccctccactt tccgtagctc tatatacaac ataatgatcc acgtcgtctg acttgcttct 25861 ttcccacgac aactggagct ctcctccaac tttaggatct acaaccttaa ggcctgaagg 25921 agtttgggga gcttctctat ccacaatgta tttcttaatt aatgatgcct ccttatttcc 25981 tttgtttact gctgttgccc gtacagcata tgttccggat gcaagacttg aaacattcca 26041 aatgcaattg gaaacaaagt agttttcccc tactcctatc tcaggaagtt cctctccctt 26101 caatattctc tccaggaagt cttccaaatc atatactttg cccggtacag gagaagaatc 26161 ttccccaatc aaatgccatg tctcatctcc gtccacaccg cttgacggcg agtctcccaa 26221 ataagcatat tcatatatga cactgacgcc caccgcatca cttattaccg tctcaatctc 26281 aagcgtactg ttggttcttg aaagttccgc cggtttcata ctgaatataa gcggactgga 26341 tgtctgatga agcgctctta tgtcaatgcc ctcacttata ttctcatctt ttgaataatc 26401 ataagttctt tcactttccc tgcccaaatc atttactacc gaaacggcat agaagtactc 26461 tttctgcgga tctctcattg tatctatata tacatttgat gttgtattgc tgactatctt 26521 ctcccaggtt ccttctcttc cctcttttct atacaaaaca tagtatctga agtcaggcct 26581 tagcaccggt gaccaactta caacaagctg ccactcccct gcctgtacat ataaatgctc 26641 cggcggtgaa ggcggatcgt ttgccaaaag atatgtatga atcttttgtg aaaagtttcc 26701 tgcagcatca cttaccataa cccttacttg ataatagccg tccggataaa gttcctctcc 26761 ttccgggcct gttgccaaag tatcccattt aacctgtact tcattctttc cgggattctg 26821 gacatctgcg ataggcgtcc attcaccatc tcctattgga ttaccgtttt catccaaagg 26881 cctgaattgg aaagaataca tatttacttc caaattatct ttcgcatatg ctgtaagcgt 26941 aactccactt cttatggaag agccgtcttc cggagtaaat ttgattatct gaggaggtgt 27001 tgtgtcactt cccggccttg cgcttactat attcgaagcc tcactttcat tcccaagcat 27061 gtcaactgct gtaactttgt agaaactatc cacatcaaga ggagccgcag tatctgcgta 27121 agagaaatcc atagtgtttt caatcagttc aaaggtgtct tcagcaccgc cttcagtact 27181 tctataaacc ctgaaatggt caaaatcctc agccttcaca gaaagttccc attccaacaa 27241 cactcgtaac tccgacgaac ttgctttaag cacaggtgca gccgggggag tattgtccac 27301 agtgtattct gaaataaatt cactaatgtt gtcggatgta tcacttacaa ctactttgac 27361 atagtacaaa ccgtcaacaa gctcttttgt attccaattt acagaacctg tggttgttgc 27421 accaatgctt tcccatgttc cttcttcctt attggaggta aacaagaatt ccatagcttt 27481 aatctttaca ttgtcagaag ctaaaacact caaccttgtt tcaccgttca cacggcttcc 27541 gtctgccgga accattccga caataacagg cggtgtaatg tcaggcaaag gttccactgc 27601 ctgacttgtt gaaccggaac tttcatttcc atatatatcc acagccttta ccatgtatat 27661 atatgtgtta ccatatagaa cattgctgtc agtatacgac attaacgcag attcatatat 27721 aagttcataa tcatgaccgt tttcacttct gtaaagcctg tatttcacaa tatcgctgtc 27781 atccaccttt gaccagacaa catctatctt tccttctccg gcaacagcct caatttgcac 27841 cggagccgcg ggcagtacca aggtaacagt caaaggttgg ctttctgcag aataatttcc 27901 tgccatatca taagctttta cagaatatgt atagctatga tccttggtaa ctttcttatc 27961 aataaacagg ttagtatcag acgtcccaac ctctatgcca tcccggtata ttttatatcc 28021 tgcaactttt acattatctg ttgatttgtc ccatgtgaga gtaatagagg attcagattt 28081 cgaaaccact ctcaagttgc taggtgcgga cggtggttct gcatctgaag ccgctaccac 28141 tgtgatactt tcactttcag gtgaaacgtt acctgcattg tcataagctc ttattatata 28201 tatgtaagtt tcatcaggag ttaaccctgt atccgtaaac ttatttcctg tgacgtttct 28261 tatatggaca ccgttacggt atattctgta tccggctact cctatattat ccgtagattc 28321 agtccattcg agagaaactg aggttgttgt tacagatgtc acaaaaacgt tttccggggc 28381 cgtaggcggc tgattgtcaa atacaacggt attactaaca tcagatacat ttcctgacgc 28441 gtcgaaagct ttcacgtaat aactgtaagt tccgggttcc aaatcgtaat cggtatacct 28501 tgtattaact gtatctgcaa tattaactcc atttctataa attttatagc ctgtaactgc 28561 agcattatct gttgaagctg accatgtcaa agtcacagaa gtgtcggttc tcgagcttat 28621 gccaagattt ttaggtgccg taggaggttc attatcaaca tcggttctga ctttgacagc 28681 ttcactaaag tccgacaaat tccggactgc atcataagct ctgacagtat acgtatactc 28741 agtattggga accaacccat ggtctatata gcttaaagtt ctggaatttc ctaccctgat 28801 accgtttctg tatatttcat acccttccac attcacatta tcttcagatg tatcccattg 28861 caacgtcaca gtggttaaag tttttgaaac cacctgcaaa ttcgttggaa cactcggagg 28921 ttcactgtct atgacttctt ctttaataat attccaaaga ggactatggc tgaaaatata 28981 tccactttcc aaaggcttgg ttataatcaa ttcattaaat cccgaatccc caggatgagt 29041 aaatgtaact ctttgcagac tttcaccgct taaaatcgtc ttatgagtac ctgttgccct 29101 gaaatttgag cttgaggaag aatcaccctt ttgtgtaaaa tcccctttaa cttcaagaat 29161 tcctgctgta agataagaag catggctgta ataactttga gttacaaagt ctctgccaac 29221 cctgacataa tcctcttcat tattcattct taaatatcca taacatctcc catactcaaa 29281 ggtaccatcc gcttgataat ttctgctctg tattctataa ctgccttcta caagaagctg 29341 acctttgttt atatacatgg tacctccgct ttgtatgaga tttcctccca ccgagagctt 29401 atatccgttc aggttaagta ttccatcgtt taaaaacagg cttcctttta tatttatatc 29461 tcttacaaga gtacggttgc catcaataca caggtcataa tcccaagtat cccagtttat 29521 tgccgtattt gtaccaatac ataaatattc tcctcctgct acaggcgtgg acgtatattt 29581 taacgctcca ttgacaaaaa cctttgatgt aaatctgaca cctttatctg aagagtttgt 29641 tatttcaagt atattaatac aggatcctga cccggaagaa ctttcgaaag ttactatttg 29701 taactcttca ccacttaaca caactctatg atttcctgta gctttaaagt tgtcatacga 29761 attatacctt ttttgtgtga aattgccttt cacttccaaa gtaccgtctg taaggtaatt 29821 ggcatgacta tgttgactat aaatcaaaaa gtctccctct accttcagat agtcagtagg 29881 ttttgtcatc ttcaagtatc cgttgctata catatttatt gtctgaccgt tacttgaagg 29941 aatttccgtt tgaatcctgt aatcgccttt tactgtcagg catccgccgt ttaaatctat 30001 aacgcctcct gattgtatta aatccccgtt aactgtaaga ttaaatccat ttaaatccag 30061 tactcctgca cctatataaa gatttcccgt atactcctcg tccgctgaca gcttccagcc 30121 tcttttctgc tctcccggaa attttatcac acatccatta tctatgaaag tattcgcgtt 30181 taaaggttga ttaaattcca ccccatcttc c //