Publications (since 2007) 1. Hayes K, Buist R, Vincent TJ, Thiessen JD, Zhang Y, Zhang H, Wang J, Summers AR, Kong J, Li XM, Martin M. (2013) Comparison of manual and semi-automated segmentation methods to evaluate hippocampus volume in APP and PS1 transgenic mice obtained via in vivo magnetic resonance imaging. J Neurosci Methods. Oct 1;221C:103- 111. doi: 10.1016/j.jneumeth.2013.09.014. 2. He J, Qiao JP , Zhu SH, Xue MZ, Chen WW , Wang  XC, Tempier A , Huang QJ, Kong J and Li XM. (2013) Serum -amyloid peptide levels spike in the early stage of Alzheimer’s disease phenotype in an APP/PS1 double transgenic mouse model. Current Alzheimer Research, 10, 979-986.  PMID24117120 3. Guan T, Liu Q, Qian Y, Yang H, Kong J, Kou J, Yu B. Ruscogenin reduces cerebral ischemic injury via NF-κB-mediated inflammatory pathway in the mouse model of experimental stroke. Eur J Pharmacol.  Jul 30. pii: S0014-2999(13)00558-X. doi: 10.1016/j.ejphar.2013.07.036. [Epub ahead of print]  PMID23911884 4. Thiessen JD, Zhang Y, Zhang H, Wang L, Buist R, Del Bigio MR, Kong J, Li XM and Martin M. (2013) Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination. NMR in Biomedicine Aug 13. doi: 10.1002/nbm.2992. [Epub ahead of print] 5. Li C, Guan T, Chen X, Li W, Cai Q, Niu J, Xiao L, Kong J. (2013) BNIP3 mediates pre-myelinating oligodendrocyte cell death in hypoxia and ischemia. Journal of Neurochemistry   2013 May 20. doi: 10.1111/jnc.12314. [Epub ahead of print] PMID: 23692407 6. Yu D, Li M, Ni B, Kong J and Zhang Z. (2013) Induction of neuronal mitophagy in acute spinal cord injury in rats. Neurotoxicity Research 2013 Apr 30. [Epub ahead of print]. PMID: 23637053 7. Chen J,  Ouyang J,  Kong J,  Zhong W and Xing, M. (2013) Photo-crosslinked and pH sensitive biodegradable micelles  for doxorubicin delivery. Applied Materials & Interfaces 5(8):3108-17. Epub 2013 Apr 15. PMID: 23530535 8. Zhang GH, Zhao YN, Li XM and Kong J. (2013) Fetal cell microchimerism in the maternal mouse spinal cord. Neurosci Bull (In press). 9. Zhang H, Zhang Y, Xu H, Huang Q, Wang L, Zhao J, Wang J, Zhang Z, Tan Q, Kong J, Li X-M. (2013) Locomotor activity and anxiety status, but not spatial working memory, are affected in short-term cuprizone-exposed mice. Neurosci Bull  29(5):633-641 10. Chen X, Guan T, Zhang X, Li C, Shang H, Cui L, Li XM and Kong J. (2013) S- Nitrosylated Protein Disulphide Isomerase contributes to Mutant SOD1 aggregates in Amyotrophic Lateral Sclerosis. Journal of Neurochemistry  124(1):45-58. doi: 10.1111/jnc.12046. 11. Tempier A, He J, Zhu S, Zhang R, Kong L, Tan Q, Luo H, Kong J, Li XM. (2013) Quetiapine modulates conditioned anxiety and alternation behavior in Alzheimer's transgenic mice. Current Alzheimer research 10:199-206, PMID: 22950914 12. Chen X, Guan T, Li C, Shang H, Cui L, Li XM and Kong J. (2012) SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S- nitrosylation of protein disulfide isomerase (PDI). Journal of Neuroinflammation 12;9:237. doi: 10.1186/1742-2094-9-237. PMID: 23061969 13. Mei F, Guo S, He Y, Wang L, Wang H, Niu J, Kong J, Li X, Wu Y, Xiao L. (2012) Quetiapine, an Atypical Antipsychotic, Is Protective against Autoimmune-Mediated Demyelination by Inhibiting Effector T Cell Proliferation. PLoS One. 7(8):e42746. doi: 10.1371/journal.pone.0042746. 14. Chen X, Guo C, Kong J. (2012) Oxidative stress in neurodegenerative diseases. Neural Regeneration Research, 7(5): 376-385. 15. Lu Y, Wang L, He M, Huang W, Li H, Wang Y, Kong J, Qi S, Ouyang J, Qiu X. (2012) Nix protein positively regulates NF-κB activation in gliomas. PLoS One. 7(9):e44559. doi: 10.1371/journal.pone.0044559. 16. Zhu, S., He, J., Zhang, R., Kong, L., Tempier, L., Kong, J. & Li, X. M. (2012). Therapeutic effects of quetiapine on memory deficit and brain beta-amyloid plaque pathology in a transgenic mouse model of Alzheimer's disease. Current Alzheimer research (2012 Aug 30. Epub ahead of print) 17. Shi R; Weng J; Zhao L, Li, XM; Gao TM and Kong J. (2012) Excessive autophagy contributes to neuron death in cerebral ischemia. CNS Neuroscience and Therapeutics 18 (3): 250–260. 18. Zhang R, He J, Zhu S, Zhang H, Wang H, Adilijiang A, Kong L, Wang J, Kong J, Tan Q, XM Li. (2012) Myelination deficit in a phencyclidine-induced neurodevelopmental model of schizophrenia. Brain Res 1469: 136–143 19. Zhang L; Wu Y; Schroedter I; Kong J; Vrontakis M. (2012) Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model. PLoS ONE 7(3): e33901. doi:10.1371/journal.pone.0033901. 20. Bi X, Zhang Y, Yan B, Fang S, He J, Zhang D, Kong J, Tan Q and Li XM. (2102) Quetiapine prevents oligodendrocyte and myelin losses and promotes maturation of oligodendrocyte progenitors in the hippocampus of global cerebral ischemia mice. Journal of Neurochemistry 123:14-20. 21. Zhang Y, Zhang H, Wang L, Jiang W, Xu H, Xiao L, Bi X, Wang J, Zhu S, Zhang R, He J, Tan Q, Zhang D, Kong J, Li XM. (2012) Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination. Schizophrenia Research. 2012 Jun;138(1):8-17. 22. Chen X, Shang H, Qiu X, Fujiwara N, Cui L, Li XM, Gao TM and Kong J. (2012) Oxidative modification of cysteine 111 promotes disulfide bond-independent aggregation of SOD1. Neurochemical Research 37(4): 835-845. 23. Niu J, Wang L, Liu S, Li C, Kong J, Shen HY, Xiao L. (2012) An efficient and economical culture approach for the enrichment of purified oligodendrocyte progenitor cells. J Neurosci Methods. Jul 30;209(1):241-9. doi: 10.1016/j.jneumeth. 24. Zou ZY, Wang XN, Liu MS, Sun Q, Li XG, Cui LY, Kong J. (2012) Identification of a novel missense mutation in angiogenin in a Chinese amyotrophic lateral sclerosis cohort. Amyotrophic Lateral Sclerosis. 13(3):270-5 25. Chen WW, Yu HL, Fan HB, Zhang CC, Zhang M, Zhang CY, Cheng YB, Kong J, Liu CF, Geng D, Xu XS. (2012) RIP1 mediates the protection of geldanamycin on neuronal necroptosis induced by oxygen-glucose deprivation combined with zVAD in primary cortical neurons. Journal of Neurochemistry 120 (1): 70–77 26. Chen J, Zehtabi F, Ouyang J, Kong J, Zhong W and Xing MQ.  (2012) Reducible self-assembled micelles for enhanced intracellular delivery of doxorubicin. Journal of Materials Chemistry 22 (15): 7121-7129. DOI: 10.1039/C2JM15277K 27. Chen J, Qiu X, Ouyang J, Kong J, Zhong W, and Xing MQ. (2011) pH and Reduction Dual-Sensitive Copolymeric Micelles for Intracellular Doxorubicin Delivery Biomacromolecules, 2011, 12 (10), 3601–3611 28. Chen J, Zhou B, Li Q, Ouyang J, Kong J, Zhong W and Xing MQ. (2011) PLLA- PEG-TCH-labeled bioactive molecule nanofibers for tissue engineering. International Journal of Nanomedicine 2011: 1–10. 29. Wang Y, Zhang Y, He J, Zhang H, Xiao L, Kong J and Li MX. (2011) Hyperforin promotes mitochondrial function and development of oligodendrocytes. Journal of Neurochemistry 119(3):555-568. 30. Zhang Z, Shi R, Weng J, Xu X, Li XM, Gao TM and Kong J. (2011) The proapoptotic member of the Bcl-2 family BNIP3 is a mediator of caspase-independent neuronal death in excitotoxicity. FEBS Journal 278 134–142. 31. Shao WH, Li C, Chen L, Qiu X, Zhang W, Huang CX, Xia L, Kong J, Tang Y. (2010) Stereological investigation of age-related changes of the capillaries in white matter. The Anatomical Record 293:1400–1407. 32. Niu JQ, Mei F, Li N,, Wang HZ, Li XM, Kong J and Xiao L. (2010) Haloperidol promotes proliferation but inhibits differentiation in rat oligodendrocyte progenitor cell cultures. Biochemistry and Cell Biology 88:611-620. 33. Wang H, Xu H, Niu J, Li XM, Kong J, Cai W and Xiao L. (2010) Haloperidol activates quiescent oligodendroglia precursor cells in the white matter of adult mouse brain. Schizophrenia Research 119:164-174. 34. Fang S, Yan B, Wang D, Bi X, Zhang Y, He J, Yang Y, Xu H, Kong J, Wu J, and Li XM. (2010) Chronic effects of venlafaxine on synaptophysin and neuronal cell adhesion molecule in the hippocampus of cerebral ischemic mice. Biochemistry and Cell Biology 88:655-683. 35. Bi X, Yan B, Fang S, He J, Li XM and Kong J.  (2009) Quetiapine regulates neurogenesis in ischemic mice by inhibiting NF-kB p65/p50 expression. Neurological Research 31:159-166. 36. Zhao ST, Chen M, Li SJ, Zhang MH, Li BX, Das M, Bean J, Kong J, Zhu XH, Gao TM. (2009) Mitochondrial BNIP3 upregulation precedes endonuclease G translocation in hippocampal neuronal death following oxygen-glucose deprivation. BMC Neuroscience 10:113 37. He J, Kong J, Tan QR and Li XM. (2009) Neuroprotective effect of atypical antipsychotics in cognitive and non-cognitive behavioral impairment in animal models. Cell Adhesion and Migration 3: 129-137. 38. Chen M, Sun HY, Li SJ, Das M, Kong J, Gao TM. (2009) Nitric oxide as an upstream signal of p38 mediates hypoxia/reoxygenation-induced neuronal death. Neurosignals 17:162-168. 39. Yu Y, He J,  Zhang Y, Luo H, Zhu S, Yang Y, Zhao T, Wu J, Huang Y, Kong J, Tan Q, Li XM. (2009) Increased hippocampal neurogenesis in the progressive stage of Alzheimer’s disease phenotype in an APP/PS1 double transgenic mouse model. Hippocampus 19:1247–1253. 40. Zhang Y, Xu H, Jiang W, Xiao L, Yan B, He J, Wang Ya, Bi X, Li X, Kong J and Li XM. (2008) Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse. Schizophrenia Research 106:182-191. 41. Xu HY, Wang H, Zhuang L, Yan B, Yu Y, Wei Z, Zhang Y, Dyck LE, Richardson SJ, He J, Li X, Kong J and Li XM. (2008) Demonstration of an anti-oxidative stress mechanism of quetiapine: Implications for the treatment of Alzheimer’s disease. FEBS Journal, 275(14):3718-3728. 42. Chen Y, McMillan-Ward E, Kong J, Israels SJ and Gibson SB. (2008) Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death and Differentiation, 15:171-182. 43. Zhang Z, Yang X, Zhang S, Ma X and Kong J. (2007) BNIP3 upregulation and EndoG translocaiton in delayed neuronal death in stroke and in hypoxia. Stroke 38 (5), 1606-1613 44. Zhang S, Zhang Z, Sandhu G, Ma X, Yang X, Geiger JD and Kong J. (2007) Evidence of oxidative stress-induced BNIP3 expression in amyloid beta neurotoxicity. Brain Research 1138:221-230. 45. Chen Y, McMillian-Ward E, Kong J, Isreals SJ and Gibson S. (2007) Mitochondrial electron transport chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. Journal of Cell Science 120: 4155-4166. 46. Yan B, Bi X, He J, Zhang Y, Thakur S, Xu H, Gendron A, Kong J, Li XM. (2007) Quetiapine attenuates spatial memory impairment and hippocampal neurodegeneration induced by bilateral common carotid artery occlusion in mice. Life Science 81(5):353-361. 47. Xu X,  Chua CC, Kong J , Kostrzewa RM, Kumaraguru U, Hamdy RC and Chua BHL. (2007) Necrostatin-1 protects against glutamate-induced GSH depletion and caspase-independent cell death in HT-22 cells. Journal of Neurochemistry, 103:2004- 2014. 48. Yan B, He J, Xu H, Zhang Y, Bi X, Thakur S, Gendron A, Kong J and Li XM. (2007) Quetiapine attenuates the depressive and anxiolytic-like behavioural changes induced by global cerebral ischemia in mice. Behavioural Brain Research 182:36-41

Book chapters

1. Li V, Bi X, Szelemej P and Kong J. (2012) Delayed Neuronal Death in Ischemic Stroke: Molecular Pathways. In “Advances in the preclinical study of ischemic stroke", ISBN 978-953-308-71-8, InTech Open Science, Rijeka, Croatia. PP 1-42. 2. Shi R, Weng J, Szelemej P and Kong J. (2012) Caspase-Independent Stroke Targets. In:  Springer Series in Translational Stroke Research: From target selection to clinical trials. Eds: Lapchak PA. and Zhang JH. ISBN 978-1-4419-9529-2. Springer Publishing, New York. PP 60-102. 3. Weng J and Kong J. (2008) Delayed neuronal death in stroke: molecular pathways. In: John H Zhang. Advancements in Neurological Research, ISBN: 978-81-308-0225-1. Research Signpost, Kerala, India. 1-38.