Credit
hours: 5
Class
contact hours:
-
Lectures:
two 75 minute lectures and one 50 minute pre-lab lecture per week
-
laboratory
(one 3 hour laboratory) per week
Course
instructors:
M.
B. Thadani, M.Sc.(Pharm.)
Room
202B, Faculty of Pharmacy
Telephone:
474-6901
Purpose
of the course:
This
course will introduce the student to the techniques used to compound medicinal
products. The physical chemical basis of product formulation and practical
aspects of choosing and preparing the appropriate dosage form will be described
and demonstrated in weekly laboratories. The pharmacist's technical and
dispensing knowledge and its impact on patient care will be covered.
Course
objectives:
After
completing the course, the student should be able to:
-
Read and
interpret the written prescription.
-
Determine
if more information is needed before the prescription can be filled.
-
Document
and annotate any additions or changes to the prescription.
-
Explain
the medicinal and pharmaceutical function of each ingredient.
-
Identify
the use of the product for the patient.
-
Locate
the source of the formula(e) through knowledge of standard reference sources.
-
Refer
to standard reference sources to determine whether there are any physical
or chemical incompatibilities.
-
Calculate
the required quantities of all ingredients.
-
Verify
the dosage and calculation for each ingredient and patient condition.
-
Develop
a procedure to compound the prescription given the above information.
-
Use the
appropriate equipment and technique(s) to compound the prescription.
-
Label
the prescription according to the requirements stated in the Manitoba Pharmaceutical
Act.
-
Counsel
the patient on the appropriate use of the compounded prescription.
Assumed
background:
The
student should have covered a first year level course in chemistry and
currently enrolled in the organic chemistry and medicinal chemistry courses
required by the Faculty of Pharmacy for the first year as stated in the
General Calendar.
Teaching
and learning methods:
An
interactive lecturing style with some material presented in didactic form
will be used Problems will be assigned for homework. Students will be expected
to work independently on their assignments and in the laboratory.
Assessment
program:
There
will be one mid-term test (1 hour) covering lecture and laboratory material
before the mid-term break worth 20% of the term mark.
Each
laboratory will be marked on a weekly basis. Each preparation will be graded
according to the scheme provided in the laboratory manual. Laboratories
will constitute 20% of the term mark.
There
will be a final practical laboratory exam at 15% of the term mark.
The
final exam (3 hour) scheduled by Student Records during examination period
will account for the remaining 45% of the term mark.
The
total of the above evaluations will be translated into the following letter
grades:
Total
Percentage (%), Achieved Letter Grade, Grade Point, Description
90
- 100, A+, 4.5, Exceptional
80
- 89, A, 4.0, Excellent
75
- 79, B+, 3.5, Very Good
70
- 74, B, 3.0, Good
65
- 69, C+, 2.5, Satisfactory
60
- 64, C, 2.0, Adequate
50
- 59, D, 1, Marginal
49
- 0, F, 0, Failure |
Recommended
texts and references:
-
Gennaro,
A. R., editor, Remington's Pharmaceutical Sciences, 2000 edition.
-
Judith
E. Thompson, A Practical Guide to Contemporary Pharmacy Practice, Williams
& Wilkins, Baltimore, 1999.
-
Rees,
J. A., Smith, I., Smith, B., Introduction to Pharmaceutical Calculations,
Pharmaceutical Press, London, 2001.
-
Thadani,
M. B., Basic Pharmaceutical Compounding, Cantext Publications, Winnipeg,
2001.
-
Thadani,
M. B., Fundamentals of Pharmaceutics Laboratory Manual, 46.119, 2003.
Topics
covered will include:
-
Prescription
balances and dilution techniques
-
Trituration
and levigation procedures
-
Solutions
-
Suspensions
-
Emulsions
-
Orientation
to hospital pharmacy
-
Ointments
-
Pastes
-
Colloids/Keratolytics
-
Dermatologicals
-
Extemporaneous
Preparations
-
Lab Exam
-
Laboratory
Check out
Late
Submissions:
Late
submissions will be given a grade of zero (0).
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24
June 2002 |