collapseTranscripts {ballgown} | R Documentation |
cluster a gene's transcripts and calculate cluster-level expression
collapseTranscripts(gene, gown, meas = "FPKM", method = c("hclust", "kmeans"), k = NULL)
gene |
which gene's transcripts should be clustered |
gown |
ballgown object |
meas |
which transcript-level expression measurement to use
( |
method |
which clustering method to use: |
k |
how many clusters to use. |
list with two elements:
tab
, a cluster-by-sample table of expression measurements
(meas
, either cov or FPKM), where the expression measurement for
each cluster is the mean (for 'cov'
) or aggregate (for
'FPKM'
, as in gexpr
) expression measurement for all
the transcripts in that cluster. This table can be used as the
gowntable
argument to stattest
, if differential
expression results for transcript *clusters* are desired.
cl
output from clusterTranscripts
that was run
to produce tab
, for reference. Cluster IDs in the cluster
component correspond to row names of tab
Alyssa Frazee
hclust
, kmeans
,
clusterTranscripts
, plotLatentTranscripts
data(bg) collapseTranscripts(bg, gene='XLOC_000454', meas='FPKM', method='kmeans')