avedups {limma}R Documentation

Average Over Duplicate Spots

Description

Condense a microarray data object so that values for within-array replicate spots are replaced with their average.

Usage

## Default S3 method:
avedups(x, ndups=2, spacing=1, weights=NULL)
## S3 method for class 'MAList':
avedups(x, ndups=x$printer$ndups, spacing=x$printer$spacing, weights=x$weights)

Arguments

x a matrix-like object, usually a matrix or an MAList object.
ndups number of within-array replicates for each probe.
spacing number of spots to step from a probe to its duplicate.
weights numeric matrix of spot weights.

Details

A new data object is computed in which each probe is represented by the (weighted) average of its duplicate spots. For a MAList object, the components M and A are both averaged in this way.

If x is of mode "character", then the duplicate values are assumed to be equal and the first is taken as the average.

Value

A data object of the same class as x with 1/ndups as many rows.

Author(s)

Gordon Smyth

See Also

dimnames in the base package.

02.Classes gives an overview of data classes used in LIMMA.


[Package limma version 2.18.2 Index]