Cellular Energetics I - Cellular Respiration & Fermentation

 

Introduction

In order to survive, grow and reproduce, all organisms require an energy source. The ultimate source of the majority of energy available to living systems is sunlight, which photosynthetic autotrophs (green Plants, some Monera, some Protista) can transform through the process of photosynthesis into chemical energy in the bonds of the hexose sugar, glucose.
Glucose, once synthesized, may in turn be stored as polysaccharide, converted into other complex organic molecules such as proteins, lipids or other carbohydrates. On the other hand, it may also be broken down releasing some of the stored energy to fuel the autotrophs own energy requiring processes.

Other organisms, the heterotrophs (most Monera, some Protista, all Fungi and all Animals), cannot use sunlight directly as an energy source, but must have in their diet complex organic molecules such as carbohydrates, lipids and proteins which serves to supply their energy needs.

Whether autotroph or heterotroph, all organisms chemically breakdown substrates releasing energy, some of which is transformed into the bonds of ATP. The energy in ATP may in turn be used to power the energy requiring functions of the organism.

The incredible number of enzyme-catalyzed reactions which occur in living cells are collectively referred to as metabolism. Some metabolic activities, such as photosynthesis are synthetic in nature and are referred to as anabolism, while break-down processes come under the heading catabolism. Cells are able to transform energy from food materials into ATP through catabolic reactions.

To the right is a diagram of the main energy yielding reactions in eukaryotes.

Notice on the diagram that glycolysis is the initial series of steps in the breakdown of glucose, a common and important energy containing molecule. The glycolytic pathway does not utilize oxygen and is found in all groups of organisms. For a summary of Glycolysis click here.

During glycolysis the six carbon glucose molecule is split into the two three carbon fragments of a substance known as pyruvic acid. The pyruvic acid may be further broken down in the absence of oxygen to substances such as ethyl alcohol or lactic acid. This process, including the glycolysis pathway, is known as fermentation. For an overview of alchohol fermentation click here.

In those organisms which perform cellular respiration the pyruvic acid generated through glycolysis is oxidized in the Krebs (Citric Acid) Cycle to CO2 and H2O. To see an overview of the Krebs Cycle, click here.

Oxygen is essential in cellular respiration as the final electron acceptor. Cellular respiration leads to a more complete breakdown of glucose and yields significantly more ATP than fermentation.


First published Sept 95: Modified June 2020
Copyright © Michael Shaw 2019 (Images and Text)

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