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Refereed Publications:


Journal of Experimental Biology, February 2023

Joyce, W., K. He, D. Bogomolny, J. Xie, M.S. Springer, A.V. Signore and K.L. Campbell. 2023. Parallel genetic excisions of the cardiac troponin I N-terminal extension in tachycardic mammals. [In revision] [bioRxiv preprint]

Signore, A.V., P.R. Morrison, C.J. Brauner, A. Fago, R.E. Weber and K.L. Campbell. 2023. Evolution of an extreme hemoglobin phenotype contributed to the sub-Arctic specialization of extinct Steller's sea cows. eLife, 12:e85414. [PDF] [eLife digest]

Tattersall, G.J. and K.L. Campbell. 2023. Thermoconforming rays of the star-nosed mole. Journal of Experimental Biology, 226(3):jeb245127. [PDF] [bioRxiv preprint]


Gusztak, R.W., R.A. MacArthur and K.L. Campbell. 2022. Dive performance and aquatic thermoregulation of the world's smallest mammalian diver, the American water shrew (Sorex palustris). Physiological and Biochemical Zoology, 95(5):438-463. [PDF]

Physiological and Biochemical Zoology September/October 2022


Devereaux, M.E.M., K.L. Campbell, D. Munro, P.U. Blier and M.E. Pamenter. 2021. Burrowing star-nosed moles (Condylura cristata) are not hypoxia-tolerant. Journal of Experimental Biology, 224(19):jeb242772. [PDF] [Inside JEB]

He, K., T.G. Eastman, H. Czolacz, S. Li, A. Shinohara, S.-I. Kawada, M.S. Springer, M. Berenbrink† and K.L. Campbell†. 2021. Myoglobin primary structure reveals multiple convergent transitions to semi-aquatic life in the world's smallest mammalian divers. eLife, 10:e66797. [PDF] [eLife digest]


Hill, R.W., G.J. Tattersall, K.L. Campbell, B. Reinfort, A.M. Breit, R.R. Riewe and M.M. Humphries 2020. Thermal imaging and physiological analysis of cold-climate caribou-skin clothing. Arctic, 73(1):40-52. [PDF]


Choy, E.S., K.L. Campbell, M. Berenbrink, J.D. Roth and L.L. Loseto. 2019. Body condition impacts blood and muscle oxygen storage capacity of free-living beluga whales (Delphinapterus leucas). Journal of Experimental Biology, 222(11):jeb.191916. [PDF]

Signore, A.V., J.L.A. Paijmans, M. Hofreiter, A. Fago, R.E. Weber, M.S. Springer and K.L. Campbell. 2019. Emergence of a chimeric globin pseudogene and increased hemoglobin oxygen affinity underlie the evolution of aquatic specializations in Sirenia. Molecular Biology and Evolution, 36(6):1134-1147. [Link]

Gaudry, M.J., K.L. Campbell and M. Jastroch. 2019. Evolution of UCP1. In Handbook of Experimental Pharmacology. Springer, Berlin, Heidelberg. Pp. 1-15. [PDF]


He, K., X. Chen, P. Chen, S.-W. He, F. Cheng, X.-L. Jiang and K.L. Campbell. 2018. A new genus of Asiatic short-tailed shrew (Soricidae, Eulipotyphla) based on molecular and morphological comparisons. Zoological Research, 39(5):321-334. [PDF]

Campbell, K.L. and A.A. Dicke. 2018. Sarcolipin makes heat, but is it adaptive thermogenesis? Frontiers in Physiology, 9:714. [PDF]

Campbell, K.L., M.J. Gaudry, K. He, H. Suzuki, Y.-P. Zhang, X.-L. Jiang and R.E. Weber. 2018. Altered hemoglobin co-factor sensitivity does not underlie the evolution of derived fossorial specializations in the family Talpidae. Comparative Biochemistry and Physiology B: Biochemistry and Molecular Biology, 224(10):150-155. [PDF]

Buck, L.T., G. Burness, K.L. Campbell, C.-A. Darveau, W. Driedzic, H. Guderley, G.B. McClelland, T.W. Moon, C.D. Moyes and P.M. Schulte. 2018. 50 Years of comparative biochemistry: The legacy of Peter Hochachka. Comparative Biochemistry and Physiology B: Biochemistry and Molecular Biology, 224(10):1-11. [PDF]


Gaudry, M.J. and K.L. Campbell. 2017. Evolution of UCP1 transcriptional regulatory elements across the mammalian phylogeny. Frontiers in Physiology, 8:670. [PDF]

Gaudry, M.J., M. Jastroch, J.R. Treberg, M. Hofreiter, J.L.A. Paijmans, J. Starrett, N. Wales, A.V. Signore, M.S. Springer, and K.L. Campbell. 2017. Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades. Science Advances, 3(7):E1602878. [PDF][supporting information]

He, K., A. Shinohara, K.M. Helgen, M.S. Springer, J. Xue-Long and K.L. Campbell. 2017. Talpid mole phylogeny unites shrew moles and illuminates overlooked cryptic species diversity. Molecular Biology and Evolution, 34(1):78-87. [PDF]


Springer, M.S., A.V. Signore, J.L.A. Paijmans, D.P. Domning, J. Velez-Juarbe, C. Bauer, K. He, L. Crerar, P.F. Campos, W.J. Murphy, R.M. Meredith, J. Gatesy, E. Willerslev, R.D.E. MacPhee, M. Hofreiter and K.L. Campbell. 2015. Interordinal gene capture, the phylogenetic position of Steller's sea cow based on molecular and morphological data, and the macroevolutionary history of Sirenia. Molecular Phylogenetics and Evolution, 91(10):178-193. [PDF]

Campbell, K.L. and M. Hofreiter. 2015. Resurrecting phenotypes from ancient DNA sequences: promises and perspectives. Canadian Journal of Zoology, 93(9):701-710. [PDF]


Weber, R.E., A. Fago and K.L. Campbell. 2014. Enthalpic partitioning of the reduced temperature sensitivity of O2 binding in bovine hemoglobin. Comparative Biochemistry and Physiology - Part A, 176(10):20-25. [PDF]

Schwarze, K., K.L. Campbell, T. Hankeln, J.F. Storz, F.G. Hoffmann and T. Burmester. 2014. The globin gene repertoire of the lamprey: Convergent evolution of hemoglobin and myoglobin in jawed and jawless vertebrates. Molecular Biology and Evolution, 31(10):2708-2721. [PDF]

Gaudry, M.J., J.F. Storz, G.T. Butts, K.L. Campbell and F.G. Hoffmann. 2014. Repeated evolution of chimeric fusion genes in the β-globin gene family of laurasiatherian mammals. Genome Biology and Evolution, 6(5):1219-1233. [PDF]

Hare, J.F., K.L. Campbell and R.W. Senkiw. 2014. Catch the wave: Prairie dogs assess neighbours' awareness using contagious displays. Proceedings of the Royal Society B: Biological Sciences, 281(1777):20132153. [PDF]

He, K., A. Shinohara, J. Xue-Long and K.L. Campbell. 2014. Multilocus phylogeny of Talpine moles (Talpini, Talpidae, Eulipotyphla) and its implications for systematics. Molecular Phylogenetics and Evolution, 70(1):513-521. [PDF]


Mirceta, S., A.V. Signore, J.M. Burns, A.R. Cossins, K.L. Campbell and M. Berenbrink. 2013. Evolution of mammalian diving capacity traced by myoglobin net charge. Science, 340(6138): 1234192. [PDF] [supporting information]


Noguchi, H., K. L. Campbell, C. Ho., S. Unzai, S.-Y. Park and J.R.H. Tame. 2012. Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallographica Section D: Biological Crystallography, 68(11):1441-1449. [PDF]

Campbell, K.L., A.V. Signore, M. Harada and R.E. Weber. 2012. Molecular and physicochemical characterization of hemoglobin from the high-altitude Taiwanese brown-toothed shrew (Episoriculus fumidus). Journal of Comparative Physiology B, 182(6):821-829. [PDF] Scientific American August 2012

Campbell, K.L. and M. Hofreiter. 2012. New life for ancient DNA. Scientific American, 307(2):46-51. [PDF]

Sato, J.J., M. Wolsan, F.J. Prevosti, G. D'Elia, C. Begg, K. Begg, T. Hosoda, K.L. Campbell and H. Suzuki. 2012. Evolutionary and biogeographical history of weasel-like carnivorans (Musteloidea). Molecular Phylogenetics and Evolution, 63(3):745-757. [PDF]

Signore, A.V., J. Stetefeld, R.E. Weber and K.L. Campbell. 2012. Origin and mechanism of thermal insensitivity in mole hemoglobins: a test of the 'additional' chloride binding site hypothesis. Journal of Experimental Biology, 215(3):518-525. [PDF]


Yuan, Y., T-J. Shen, P. Gupta, N.T. Ho, V. Simplaceanu, T.C.S. Tam, M. Hofreiter, A. Cooper, K.L. Campbell and C. Ho. 2011. A biochemical-biophysical study of hemoglobins from woolly mammoth, Asian elephant, and humans. Biochemistry, 50(34):7350-7360. [PDF]

Weber, R.E. and K.L. Campbell. 2011. Temperature dependence of haemoglobin-oxygen affinity in heterothermic vertebrates: mechanisms and biological significance. Acta Physiologica, 202(3):549-562. [PDF]

Campbell, K.L. and N.T. Price. 2011. Star-nosed mole in McGraw-Hill Yearbook of Science & Technology. McGraw-Hill Publishing, New York, NY, pp. 317-320.


Campbell, K.L., J.F. Storz, A.V. Signore, H. Moriyama, K.C. Catania, A. Payson, J. Bonaventura, J. Stetefeld and R.E. Weber. 2010. Molecular basis of a novel adaptation to hypoxic-hypercapnia in a strictly fossorial mole. BMC Evolutionary Biology, 10:214. [PDF] Nature Genetics May 2010

Campbell, K.L., J.E.E. Roberts, L.N. Watson, J. Stetefeld, A.M. Sloan, A.V. Signore, J.W. Howatt, J.R.H. Tame, N. Rohland, T-J. Shen, J.J. Austin, M. Hofreiter, C. Ho, R.E. Weber† and A. Cooper†. 2010. Substitutions in woolly mammoth hemoglobin confer biochemical properties adaptive for cold tolerance. Nature Genetics, 42(6):536-540. [PDF][supporting information]

Matheson, A.L., K.L. Campbell and C.K.R. Willis. 2010. Feasting, fasting and freezing: energetic effects of meal size and temperature on torpor expression by little brown bats (Myotis lucifugus). Journal of Experimental Biology, 213(12):2165-2173. [PDF][supporting information]

Weber, R.E., K.L. Campbell, A. Fago, H. Malte and F.B. Jensen. 2010. ATP-induced temperature independence of hemoglobin-O2 affinity in heterothermic billfish. Journal of Experimental Biology, 213(9):1579-1585. [PDF]

Elliott, K.H., A. Shoji, K.L. Campbell and A.J. Gaston. 2010. Oxygen stores and foraging behavior of two sympatric, planktivorous auks. Aquatic Biology, 8(3):221-235. [PDF]

Hindle, A.G, J.M. Lawler, K.L. Campbell and M. Horning. 2010. Muscle aging and oxidative stress in wild-caught shrews. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology, 155(4):427-434. [PDF]


Opazo, J.C, A.M. Sloan, K.L. Campbell† and J.F. Storz†. 2009. Origin and ascendency of a chimeric fusion gene: the β/δ-globin gene of paenungulate mammals. Molecular Biology and Evolution, 26(7):1469-1478. [PDF]

Hindle, A.G, J.M. Lawler, K.L. Campbell and M. Horning. 2009. Muscle senescence in short-lived wild mammals, the soricine shrews Blarina brevicauda and Sorex palustris. Journal of Experimental Zoology - Part A: Ecological Genetics and Physiology, 311A(5):358-367. [PDF]

2008 and earlier

Kawada, S., S. Li, Y. Wang, O. Mock, S. Oda and K.L. Campbell. 2008. Karyotype evolution of shrew moles (Insectivora: Talpidae). Journal of Mammalogy, 89(6):1428-1434. [PDF]

Catania, K.C., J.F. Hare and K.L. Campbell. 2008. Water shrews detect movement, shape, and smell to find prey underwater. Proceedings of the National Academy of Sciences, 105(2):571-576. [PDF][supporting information]

Shinohara, A., K.L. Campbell and H. Suzuki. 2005. An evolutionary view on the Japanese talpids based on nucleotide sequences. Mammal Study, 30:S19-S24. [PDF]

Hosoda, T., J.J. Sato, T. Shimada, K.L. Campbell and H. Suzuki. 2005. Independent non-frameshift deletions in the MC1R gene are not associated with melanistic coat coloration in three mustelid lineages. Journal of Heredity, 96(5):607-613. [PDF]

Gusztak, R.W., R.A. MacArthur and K.L. Campbell. 2005. Bioenergetics and thermal physiology of the American water shrew (Sorex palustris). Journal of Comparative Physiology B, 175(2):87-95. [PDF]

Shinohara, A., H. Suzuki, K. Tsuchiya, Y. Zhang, J. Luo, X. Jiang, Y. Wang and K.L. Campbell. 2004. Evolution and biogeography of talpid moles from Continental East Asia and the Japanese Islands inferred from mitochondrial and nuclear gene sequences. Zoological Science, 21(12):1177-1185. [PDF]

Gusztak, R.W. and K.L. Campbell. 2004. Growth, development and maintenance of American water shrews (Sorex palustris) in captivity. Mammal Study, 29(1):65-72. [PDF]

Lou, J., D. Yang, H. Suzuki, Y. Wang, W-J. Chen, K.L. Campbell and Y. Zhang. 2004. Molecular phylogeny and biogeography of Oriental voles: Genus Eothenomys. Molecular Phylogenetics and Evolution, 33(2):349-362. [PDF]

Hindle, A.G., I.W. McIntyre, K.L. Campbell and R.A. MacArthur. 2003. The heat increment of feeding and its thermoregulatory implications in the short-tailed shrew (Blarina brevicauda). Canadian Journal of Zoology, 81(8):1445-1453. [PDF]

Rubenstein, N.M., G.R. Cunha, Y.Z. Wang, K.L. Campbell, A.J. Conley, K.C. Catania, S.E. Glickman and N.J. Place. 2003. Variation in ovarian morphology in four species of New World moles with a peniform clitoris. Reproduction, 126(6):713-719. [PDF]

Shinohara, A., K.L. Campbell and H. Suzuki. 2003. Molecular phylogenetic relationships of moles, shrew-moles and desmans from the New and Old Worlds. Molecular Phylogenetics and Evolution, 27(2):247-258. [PDF]

MacArthur, R.A., G.L. Weseen and K.L. Campbell. 2003. Diving experience and the aerobic dive capacity of muskrats: does training produce a better diver? Journal of Experimental Biology, 206(7):1153-1161. [PDF]

McIntyre, I.W., K.L. Campbell and R.A. MacArthur. 2002. Body oxygen stores, aerobic dive limits and diving behaviour of the star-nosed mole (Condylura cristata) and comparisons with non-aquatic talpids. Journal of Experimental Biology, 205(1):45-54. [PDF]

MacArthur, R.A., M.M. Humphries, G.A. Fines and K.L. Campbell. 2001. Body oxygen stores, aerobic dive limits, and the diving abilities of juvenile and adult muskrats (Ondatra zibethicus). Physiological and Biochemical Zoology, 74(2):178-190. [PDF]

Campbell, K.L. and P.W. Hochachka. 2000. Thermal biology and metabolism of the American shrew-mole, Neurotrichus gibbsii. Journal of Mammalogy, 81(2):578-585. [PDF]

Campbell, K.L., I.W. McIntyre and R.A. MacArthur. 2000. Postprandial heat increment does not substitute for active thermogenesis in cold-challenged star-nosed moles (Condylura cristata). Journal of Experimental Biology, 203(2):301-310. [PDF]

Campbell, K.L., I.W. McIntyre and R.A. MacArthur. 1999. Fasting metabolism and thermoregulatory competence of the star-nosed mole, Condylura cristata (Talpidae: Condylurinae). Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 123(3):293-298. [PDF]

Campbell, K.L. and R.A. MacArthur. 1998. Nutrition and the energetic tactics of muskrats (Ondatra zibethicus): morphological and metabolic adjustments to seasonal changes in diet quality. Canadian Journal of Zoology, 76(1):163-174. [PDF]

Campbell, K.L., G.L. Weseen and R.A. MacArthur. 1998. Seasonal changes in water flux, forage intake, and assimilated energy of free-ranging muskrats. Journal of Wildlife Management, 62(1):292-299. [PDF]

Campbell, K.L. and R.A. MacArthur. 1997. Urea recycling in muskrats (Ondatra zibethicus): a potential nitrogen-conserving tactic? Physiological Zoology, 70(2):222-229. [PDF]

Campbell, K.L. and R.A. MacArthur. 1996. Digestibility of animal tissue by muskrats. Journal of Mammalogy, 77(3):755-760. [PDF]

Campbell, K.L. and R.A. MacArthur. 1996. Seasonal changes in gut mass, forage digestibility and nutrient selection of wild muskrats (Ondatra zibethicus). Physiological Zoology, 69(5):1215-1231. [PDF]

Campbell, K.L. and R.A. MacArthur. 1994. Digestibility and assimilation of natural forage by muskrat. Journal of Wildlife Management, 58(4):633-641. [PDF]

MacArthur, R.A. and K.L. Campbell. 1994. Heat increment of feeding and its thermoregulatory benefit in the muskrat (Ondatra zibethicus) Journal of Comparative Physiology B, 164(2):141-146. [PDF]

authors contributed equally

Manuscripts in Preparation:
(i.e., experiments finished, data analyzed, and paper being written):

Campbell, K.L., S.G. Reid, W.K. Milsom and Y. Dzal. Metabolic and respiratory responses of true moles to thermal and ventilatory challenges.

Munro, D., D.W. Hart, R. Sebaa, N.C. Bennett, E. Van dermeeren, B. van Jaarvsveld, M.E.M. Devereaux, K.L. Campbell, P.U. Blier, M.-E. Harper and M.E. Pamenter (2023) Cardiac mitochondrial succinate dehydrogenase activity predicts whole-animal hypoxia-tolerance in rodents.

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