Xie
Lab |
|
List of SS Matrices/Constraints | Ensembl (Genome) Release # |
Last updated |
3SS_5SS_Matrices_R43/R96 | R43/R96 | 6-07-2019 |
3SS_5SS_Matrices_R40/R93 | R40/R93 | 9-26-2018 |
3SS_5SS_Matrices_R38/R91 | R38/R91 | 5-09-2018 |
3SS_5SS_Matrices/ConstraintsR36/R90 | R36/R90 | 3-26-2018 |
What else could
these
matrices be used for in so many species? Here are some
examples:
To assess the effect of a mutation on a splice site in any of the species.
To assess the effect of a SNP on a splice site.
To assess the possibility for a cryptic splice site(s) in the genome to cause aberrant splicing of any of the species.
To help make mutations within a splice site for splicing reporter or other assays.
Questions or suggestions? E-mail.
Nguyen H, Das U, Xie J. Genome-wide evolution of wobble base-pairing nucleotides of branchpoint motifs with increasing organismal complexity. RNA Biology, Dec. 2019, http://dx.doi.org/10.1080/15476286.2019.1697548.
Research in this lab has been supported by CIHR , NCIC, CBCF, NSERC, MMSF, MHRC and CFI.